"maybe so, this is a cure for your own carelessness, lack of discipline, right? yes, even, even if, even if we assume that the loan is for treatment, this means that you did not foresee in advance the risk of the possible occurrence of some kind of -that is, some situation when expensive treatment is needed, this can be foreseen, this is not something that is possible, this must always be foreseen, that is, this is one of the expenses, this is the so-called airbag, yes, or plus high-quality medical insurance , those i don’t want to get into this anymore..." we won’t get into it now, but there are programs that for little money allow you to insure for risky diseases, serious diseases for normal amounts, i think this is a benefit for everyone, that is, everyone should do, let’s delve into this topic a little bit, let’s delve deeper into the airbag, are you a supporter or not of such savings, well, whatever you can call them, yes , of course, it’s obligatory without this, how much, how much does a family owe on average monthly expenses have it in your pillow? security, well, 3-6 months

of life is enough, of course, if an entrepreneur who has an unstable income, some self-employed person, well, maybe for a year, but in fact 3-6 months is enough, usually a person can get up and rise in 3-4 months and change something in your life, or it will be the amount that will be spent on those very unexpected extra illnesses, something else, no, no, that’s exactly if. we are talking about medicine, and this could involve spending tens of millions of rubles there, but here good insurance will help, it ’s inexpensive, you don’t need loans, you can plan everything in advance and just take it into account, think about it, think through the risks, well, in general, summarizing our conversation, the topic is actually endless, and we’ve now only covered the first layer, telling our audience , that the answer to the question of how to start managing a family budget, the answer is very simple: start, well

, really, no matter how funny and simple it sounds, just start writing down all your expenses and income, then the understanding will come on its own, well, if you reconsider once again ours podcast, how to work with it, what mistakes there are, and then having completed this task correctly, you will come to financial planning, where you can set long-term goals and objectives, including your own development and the development of your children, that is, going deeper to infinity. to any horizons, thank you very much, alexey, i think that we had a very good conversation, sorted out mistakes, recorded them, walked around somewhere, trampled around just enough to remember it, especially thank you for that wonderful advice about burning, if you missed this moment, be sure to review it, regarding burning money, yes, yes, yes, you heard right, there is a very useful exercise when you need to burn money, it was the easy money podcast, its

host is mikhail khanov, and we talked about family budget, all episodes of the easy money podcast can be found on the channel one website, hello, this is the deception of substances podcast, with you olesya nosova, editor-in-chief of komsomolskaya pravda, and with me zukhra pavel. famous doctor-endocrinologist and today we will talk about hormones of happiness, as it turns out, this is very controversial topic, because it turns out that our hormones, which bring us happiness, are very actively used in negative emotions, that’s right, everywhere, everything is two-faced, you and i say in almost every program that the same substance can give us positive properties, can give negative ones, and so everything in the body, and the most important thing in this body is balance, yes... every substance has

some, well, let’s say, priority or dominant property, but when interacting with something to others, this property is reduced, increases, changes, that’s also all feelings, you know, there is an expression that love is a chemical feeling, the meaning is that they say that if you introduce certain substances, a person will experience the same sensation that he experiences when he is in love, this is true, well, essentially yes, i really don’t know how this can be reproduced. because yes, of course, there are some active substances, well , there are several of these basic ones, but at this moment everything in the body changes, the balance of everything - active substances, and hormones, and there neurotransmitters, that is, those substances that act in the brain, there are a huge number of them, they all change, but it’s not just the substances themselves, but also their receptors, yeah, because if there are no receptors, what will the hormones act on?

let’s say there won’t be any action, yeah, okay, let’s still name what our most important hormones of happiness are, well, that’s what you are, you’re not a doctor, what hormones do you associate with... with endorphin, of course, endorphin, yeah, and you know the etymology of the word, something related to morphine, no, well done, yes, enda is always something internal, and morphine is from the greek god morpheus, who was considered such a ruler of dreams, yeah, and endorphins also act on the receptors that we have they are called apiate, associated with opium, yes, well, they were probably discovered - and so they were called, they are associated with nuciception, with pain, yeah, and that is, they prevent or block pain sensations, this is the historical reference: endorphin is first just what doctors associate, well, to me

it seems like this with pain relief, but with happiness, yes, well, in principle, yes, there it gives this feeling of such endorphin euphoria. so there is such a historical reference, there is such a story that when some ancient greek battles happened in ancient greece there were some battles, there were a lot of chopped people, chopped puncture wounds like that, and many of them did not die right away, they remained on this field to die or they could try to save someone, so giter had such a mission, they found themselves on... on this field, they specially arrived there, what should we call them, a landing party, yes, a rescue landing party, they, well, did something like a massage to these people who could not be saved, at that moment they received a release endorphins, yeah, they didn’t feel so much

pain, they died, well, without such pronounced torment, these women had such an effect to help the wounded go into another world with less... suffering, it turns out exactly what we were talking about at the very beginning, when the hormone of happiness endorphin is released in response to pain, yes yes, let's see, we have a wonderful sign, the first thing that stands here is endorphin, it gives this pleasant feeling of such bliss, when euphoria, here it is on the very bottom row, this is also only endorphin, pure endorphin and there's a lot of it, because if you pay attention. on these bubbles, the amount of this substance is also very important, any of these substances in excess can cause, now if you go to another picture, then there should have been such a bottle, it should have been blue color, when this blue color

is right up to the very top, then a person falls into mania or mania, and as psychotherapists say, when you talk about dopamine, yes, i’m talking about... when dopamine, well, let’s say, is a little more than half, then these are napoleons like this, these are people who are leaders, these are people who are capable of taking responsibility, these are people who are interested in everything, they are literally captivated by everything , they are capable of learning, remember vysotsky has few real brawlers, so there are no leaders , that is, there in that konachikov dacha there were... few people with dopamine, with a good level of dopamine, here we have dopamine written, and many pronounce it as dopamine, it’s the same thing, and this is a substance without which such leadership properties cannot exist, it’s a really good substance, but if

there is too little or too much of it, then there will be a completely negative connotation, and many medications, when a psychotherapist or psychiatrist encounters a person... well, let’s say, with such a suppressed emotional background, with such apathy, indifference and more with a number of such important things, then dopamine will play a big role here, products containing this substance that increase its level will help a person live well, what is the difference between dopamine and endorphin, how many happiness hormones are there, well, a lot of different things are written here important substances, and we don't associate it. testosterone with the hormone of happiness, but it brings happiness, but i have not seen happy people with low testosterone levels, this does not happen, moreover, by the way, here is a good example to we have developed testosterone, let's say we take men, yes, it is produced in the scrotum,

in the testicles, its main place, there are also adrenal glands, there will be a little testosterone there, but more of this is the main organ of the male testicle for the synthesis of testosterone, so that... it is produced there, it is necessary for the luteinizing hormone to be produced in the head, in the pituitary gland, it is called lh, so for lh to be produced, dopamine is needed. yeah, but in order for dopamine to be produced, you need thyroid hormone and so on, that is, they are all with each other each other are interconnected, well, there is like some kind of entrance to this labyrinth, what needs to be done in order for you to have a lot of happiness hormones, that’s how many of them you need, a little, a lot of mistakes, how much is needed, balance is needed, but they attribute the second to yakaterina, she she said that happiness is a good character and talent, we know talented people, they painted beautiful paintings there or sculptures

or played music there, but if they are quarrelsome, if they don’t have enough of that same oxytocin, now i’ll tell you about it, uh-huh, or serotonin, they are uncommunicative, they are so irritated, they communicate poorly with colleagues and - friends, let's say, so, if a person... has an imbalance, then - he will look either, well, figuratively speaking, bad, or irritable, he will not be happy with himself, and someone finds it a burden, well, for example, oxytocin, oxytocin is a hormone that is produced in our pituitary gland, we have such an organ, and this is a hormone that gives a feeling of kinship, closeness, and before childbirth and in general during pregnancy, and ...hormone levels change and, as mothers say, they feel instinct faster

motherhood, than the instinct of paternity, and dads later join in these parental feelings, dads also have oxytocin, yes, but not always and not like moms, now i’ll tell you about oxytocin, this feeling of unconditional love is that including oxytocin, but not only it, not only that... but it plays a very active role in childbirth, it literally pushes out the fetus, it increases such muscle contractility, the same contractility will then be in the mammary glands, so that milk, and lactation could come true, so oxytocin is when close people become family to each other, or when a person has a feeling of such kinship, and says: oh, it’s like i ’ve known you for 100 years, this means that it’s a throwaway. some more cunning speakers, yeah, there are sytocin that penetrates into these relationships, and

this opinion, oxytocin is sprayed into the air, in my opinion, this does not have a strong effect, but still has a certain grain of rationality at its core, and thus the audience becomes more inclined towards this, i think they themselves they sniff out this and a more receptive audience, it’s all very simple. there is another one like this, here’s a hint, when a person wants to achieve a more loyal attitude towards himself, he offers to drink coffee, the smell of coffee is coffee itself, it promotes the synthesis of oxytocin, and this inspires more trust, i studied the literature very carefully in search of any specifically oxytocin, because for me it was the most incomprehensible of these happiness hormones.

and so on, with oxytocin it’s a different story, there are several studies - quite convincing - that with age, not all, but many, begin to produce more oxytocin, and this, by the way, explains why old people in old age believe that they have lived a long, happy life there, for example, because this oxytocin, it slightly changes the perception of reality and so on, in general, this is what i think happens naturally.

in order for us to feel this happiness, we need serotonin, and it is produced mainly in the intestines, oddly enough, exactly there, and dopamine, on the contrary, is synthesized somewhere around 90% in... the brain, only 10% in the adrenal glands, they are very similar to each other, but still dopamine was considered a hormone that gives a feeling of maximum pleasure. this is the result, not so long ago scientists came to the conclusion that dopamine is a feeling

of lust, a feeling of some kind of approaching victory, this is languor, this. experience it again, experience it again, but it’s better, of course, looking at the athletes playing there. beauty back to work galloped up, are you slow today? am i old? no, why? can you come to me? your potapav, he doesn’t work as a builder or as a doctor, he catches murderers and bandits every day. our department is now in good standing, not without

help, ugly, i saw, there was a murder, i greet you, coleostro, i see people, those who are here, those who are far away, sometimes what was, sometimes what will be , do you want to live with me, at home at night, because i ’m not going to sit by the window like a fool and wait for you until midnight, that’s clear, that means i kozlevich, exactly, what a kozlevich, marinette, not me, of course, not you, which means you also love him very much, i love him, guesser. new episodes, tomorrow on the first, it was a time of big ideas, it was a time of very big and different dreams, soviet films that

were filmed at vdnkh gave an idea of ​​the power and beauty of this object. and we continue our podcast and today it is dedicated to hormones of happiness. with you is zukhra pavlova, an endocrinologist, and olesya nosova, editor-in-chief of komsomolskaya pravda. by the way, it’s interesting what can be done genetic analysis to find out your predisposition, what, what, what hormones do you naturally produce

more? well, it’s possible, but it’s possible if we know something. myself, well, or i look at patients, if i see a person with connective tissue dysplasia, this is such a large, so to speak, pool of disease conditions, these people, as a rule, or maybe, let’s say, have a balance between adrenaline, norepinephrine, adrenal hormones and cortisol in favor of adrenaline, norepinephrine, and serotonin in these people may also be less, they are prone to various depressions.

results on the sensitivity of receptors, their structure, this moment, i freeze, i really want to see this result, because i immediately begin to calculate, it will most

likely be this, this, this, yes, when i see that coincidentally, here i have serotonin and it’s just pleasure and happiness, by the way, when there is a lot of oxytocin, with some good level of serotonin, these people are so loving, indiscriminate, and they can even be stigmatized somehow, that... . they say, yes, they are not very guilty, their balance of hormones is such that they are not very much their own masters, well, what to do in this situation, only social norms, self-education, control, well, so that, as they say, they do not go into all sorts of troubles, well, it’s often true that it’s determined by some properties, that’s how i say sometimes, you’re walking down the street, three people beat one, what’s your reaction, he says, what a fool, maybe he’s even supposed to, i should add, i. .. he understands that a person with cortisol has everything in order, that’s adrenaline and his norepinephrine is under control, when a person says: i don’t know anything, when there are three against one, this is all injustice, i

went there and climbed in, i need to break it all apart, here the person doesn’t have time to think, especially he has little norepinephrine, and adrenaline is just enough for him to immediately get into the thick of things, and then he may even regret it, but a person is not always his own master, he often... acts on such impulses, on such basic ones, yes, on how he works. and then what to do? well, actually, life experience helps a lot. scars? yes, yes, yes, yes, because no one is able to learn from other people’s mistakes, this is this, this is a myth, another medical myth. moreover, one of the biggest tragedies in my life was the information that only 5% of people learn from their mistakes, everyone else regularly repeats them. so i really want to be there. that the chosen ones get there, this is another very important point,

that the excess or deficiency of hormones of these neurotransmitters, and biologically active substances that affect brain cells, well, in fact , they affect the entire body, various diseases arise, for example, autism is absolutely associated with... a deficiency of oxytocin, not only, there will be serotonin and dopamine, but this does not mean that there is not enough dopamine, dopamine , and they are very trainable, they are not able to give out this information in the form we are familiar with, let’s say parkinson’s disease has such a core, such a place in the brain, called the substantia nigra, substantia nigra, latin name, it is destroyed, the metabolism of that is disrupted dopamine itself. and parkinson’s disease develops, all over the world they are struggling with this complex disease, there were very interesting works on such, say, non-standard

use of testosterone replacement therapy, testosterone restoration therapy at the polish andropause institute, where they obtained good results in relation to parkinson’s disease, but basically, they restored the level of testosterone in parkinson's patients, they truly stimulated it. or the synthesis of this same testosterone, improving the clinical manifestations of parkinson's disease. that there are, roughly speaking, people have experienced less movement disorders , but still the main active medicine, the first line, as they say, are drugs based on and acting on dopamine receptors. you can even touch on one more such, i would say global topic, it is extremely interesting in relation to our today's hormones of happiness, this is obesity, which means... we have such a zone in the brain, arcuate nuclei, and not only in it, in there are a lot of serotonin receptors, it’s just a minefield there,

this means that if you act on one receptor , some h2s, then a person, this is a serotonin receptor, will immediately go to throw himself out of the window, serotonin is the hormone of happiness, and that’s not the point, if you act on a receptor there, some a1, then.. . a person will have a feeling of love, falling in love, happiness, if you influence any a2 receptor, then the person will lose his appetite, by the way, look, when a person is in love, remember, he doesn’t want to eat, he doesn’t notice fatigue, the world is beautiful, he in the same house the same people live around people, but everything becomes beautiful, good, kind, wonderful, and you don’t feel like eating, i mean, when once in... a drug was created for weight loss, it acted specifically on the serotonin receptor, it had that name fenfen, everyone happily rushed to lose weight on it,

but it was a very large one... a number of people began to die in suicides with cardiovascular complications, only then it turned out that the receptors for the same hormone have different modifications and completely different actions, so when you create a medicine, affecting some dopamine receptors, serotonin receptors, and you do not have subtle knowledge of this selectivity, that is, selectivity, you can get.

overweight, and the psychotherapist prescribed him medications, which, yes, are really effective against depression, there is more serotonin, the person lives a much better emotional life, but he is gaining weight, and i say: let’s go with your psychotherapist and try together, in agreement, to help patient, we will change one drug to another, if possible, so that achieve two effects: weight loss and depression. it’s called overcoming, moreover, if a person improves his appearance, but for him this is a priority, well, someone really realizes how harmful excess weight is to health, and he wants both, when he has also achieved this goal, then his emotional background will definitely improve. zukhra, i don’t understand a little, if there are antidepressants that have the same effect, but one has a side effect of excess weight, and the other

, on the contrary, has a beauty shot, why? are overweight? look when to see a psychotherapist a patient came with depression, he still thinks more in terms of depression, the doctor is more inclined to this, as, for example, in gynecology, two absolutely identical drugs from the class of progesterone hormones, one has long-term negative effects on the cardiovascular system , and the other does not, but... his practical activity has a place for these studies, he does not have time, yes, doctors, unlike very many other specialists, undergo permanent, five-year, advanced training there,

certifications and so on and so forth. and this is not right before receiving the certificate, for 5 years all the time there are conferences, conferences, seminars, training and so on, but this information still does not always reach you when you, well, that is, it depends on the knowledge of the qualification, well, not always colleagues they go to interact, this is such a multifactorial story, and hormones, hormones in general, they do not have one point of application, one system, is it gynecology, is it urology? our hormones have receptors in absolutely all organs and tissues, and amateurs who jump from trains, from high-rise buildings and so on, and people who stimulate the synthesis of adrenaline, we always say: oh, adrenaline junkie, yes, he drives fast there or takes some kind of risk, this is also about very strong sensations, which literally cause addiction, and a person takes risks and risks and cannot stop, a kind of mania.

this is a podcast deception of substances, we are talking about hormones of happiness, with you olesya nosova from ukhra pavlova. you said that there is a lot of dopamine, for example, this is mania. yes, maybe maybe serotonin is a safe hormone of happiness, can there be too much serotonin and what negative consequences can this have? well, they are extremely unpleasant, these are severe conditions, including hallucinations, sensations arise when a person. is lost in space, he experiences extremely negative sensations, they resemble such heavy sensations associated with fear, almost animal fear, so an excess of anything, the most wonderful substance, will be negative for a person, the basic principle of medicine is to do no harm quantumsatis, as much as necessary, then the person is happy, moreover, we

say very often. everything is fine, suddenly you directly, as they say, feel this pleasant state, but really everything is fine, why am i, that is, here, yes, this is all modifiable, that is, we can stimulate the synthesis of good substances, first, as it were, realizing, and then feeling, but we can eat something pleasant, but it’s very interesting what we can eat in order to become happy, is it really a cake, well, that’s how it works. human systems body, when we first of all have to want to eat, when we lose energy, when we may face incapacity, i don’t know, lose consciousness at a low sugar level, so in order to quickly replenish

this same energy when we lose energy, we reach for something - something that quickly compensates us, it’s sweet, we really experience this feeling of pleasure, but it’s like... well , it’s true, first you ate candy and so on, and then you sit and feel sad, why am i so weak-willed for seconds on my tongue life on hips, yes, there is a well-known saying, well, okay, but alcohol, alcohol, what hormone stimulates alcohol, that yes, everything that leads to addiction, yes, that is, they are all a little bit here, not only dopamine causes. addictions and serotonin leads to such needs and adrenaline is there, it will all be acetylcholine, by the way, it will all be a little bit, a little bit, but stimulate this dependence, directly create reflexes, and the person is like -

like a zombie will then reach for it because someone is abusing alcohol he says, my god, it’s a pipe, it’s such a disgusting smell, it’s a nasty taste, the one who loves to smoke says, well, you’re turning this into alcohol. it’s not clear why, it’s just an aristocratic habit, a beautiful appearance, and so on, but here we don’t approve of any servant, no matter how beautiful it looks and no matter how it’s described, it’s all definitely very harmful to health, according to about what else to eat, well, look, chocolate not only gives us pleasure, but it gives us an amino acid, tryptophan, from it, just like in bananas, for example, it is produced from it. and from serotonin then the wonderful hormone melaton, but if there is a lot of this melatonin, then very serious all sorts of unpleasant conditions develop, that’s because there is a deficiency, a person does not sleep, becomes angry, irritated, tired, incapacitated, that

when there is a lot of it, all sorts of terrible things are formed psychological nuances, melatonin is a hormone of the night, well, let’s call it the hormone of the night, it is also called the hormone of sleep, but not only, but the hormone of... everyone says no, it’s a dream does not cause, no, let’s say, it prepares for this event, but in most heads, and ours, it is still associated with sleep, yeah, but, in addition, with the correct functioning of not only melatonin itself, but also, let’s say , related melanocyte-stimulating hormone and its receptors, forgive such complex names, this also provides us with very ... oncological protection, so it is important that there is plenty of everything, by the way, when such work was done, when results were revealed showing, what when melanocyte stimulating hormone

goes away ahead of time, decreases, yes ahead of time, a person sits up faster, and this is one of these indirect signs that there may be a higher alertness for cancer than in people... this is not a death sentence, this, of course, is just alertness, you need to go for a medical examination once a year, go through the basic research methods that are required by age and gender, protect yourself from walking around with some formidable, unpleasant conditions, and wait for them to manifest themselves, which means already will late, uh-huh, okay, so what? can still make us happy? what about physical activity? you know, many athletes go to the gym, not because some kind of necessity drives them there, they enjoy it, and when i work out regularly without, say, long

breaks, this unfortunately happens in life, then i again begin to experience pleasure from physical activity, moreover, it even happened that it came to the point that you didn’t work out, went to bed and you were right. you feel how this body is for you, that is called, it knocks on the head because he didn’t have enough, this pleasure, it arises when a person has acquired training, there is such a... phenomenon, such a training effect is when inflammatory factors do not increase greatly due to physical activity, but line up in such a balance that a person receives a greater release of that same oxytocin, serotonin, dopamine after physical activity or during physical activity, he consolidates this as pleasure and the next time he goes to the gym with more with pleasure, because he will again get this pleasant feeling when...

such contradictions, there are no contradictions, but it’s very interesting, of course, very interesting, remember, i told you all the time, i give this example, you and i looked at one same sand, only i left it on one side, you on the other, you say, look how beautiful it is, green, and yellow, and marsh color, and brown, and so on, i looked carefully, took off my glasses, put on glasses, i saw only yellow color, i think i'm probably on the other side of the sun's rays he doesn’t look right, i walked around, stood in exactly the same place, i didn’t see anything from any direction. then she laughed and said there, i have 20,000 rods and cones,

like devices that help us form and perceive the spectrum of light, and you have 2 billion of them, so you see things that i will never see, and an artificial brain , unlike humans, have the ability to retain, analyze, and produce different options for all this information; if you look at an event 100 years ago, you can predict what will happen around now, because everything in this...

this is a podcast of burning with fire and i am its host denis gorelov with a story about the ninety-fifth anniversary of our great compatriot vasily makarovich shukshin. vasil makarovich was called the last genius of russian literature - that’s enough. bright writer vyacheslav alekseevich pietsukh, editor-in-chief of the magazine rural youth, which did not have too much popularity, but was a very good magazine, this is my answer, i am his... this is exactly how we will, in fact, evaluate and talk about this man, not as an outstanding one, not as a bright, in any way significant, but as the last genius of the russian word, quite comparable with the bas-reliefs of our great compatriots studied in school, first of all, frankly speaking, with anton

pavlovich chekhov, despite to the rather striking external difference between the long-spectacled... practicing doctor, shukhshin, an equally significant, important cinematographer, and at night, instead of resting, he sat down with a cigarette and wrote stories in a student notebook for 3 kopecks on 12 sheets, a ballpoint pen, his contemporaries

talked about this, both chekhov and shukshin knew enormous fame during their lifetime, and both were very popular because of... their literature and their side specialties. both were grandiose womanizers, biographers do not talk about this very seriously, but before they linked their fate with their wives, both vasily makarovich and anton pavlovich had a very large number of adventures. in various interviews, even such a women's favorite as nikolai yuremenko jr. said that before the race in width, vasil makar.

perfection of his literary reputation, but never wrote it, limited himself to plays, wrote lyubavina’s shukhshin novel, this novel did not add anything to him at all, the novel did not become great literature, unlike small stories written down to the last line, to the last letter, probably people , which work with the phrase to such a precise extent, and should not...

are caricatures, my son-in-law stole drov's car, they absolutely did not look good on the screen. the value of his literature was in the special construction of the phrase, which, of course, could not be transferred to the screen, therefore, by the way, even though his films were relatively successful, not a single one failed,

with mm -