the united states of america - this is very , very, very serious. you know, these days everyone expects an exchange of blows, but in fact , diplomacy has sharply intensified, not very visible, but very substantive in relation to the post-conflict settlement, which will include such a delicate question, who will pay for the restoration. of everything that the gases have done. the americans have already thought out a scheme by which they will pull saudi arabia as the main restorer. the very means of destruction, but they don't really want to invest. western europe and europe as a whole will also participate, but not as massively as it was on some previous conflict conflict phenomena. and here.

hamas. tony blinken, the secretary of state of the united states now needs to kill the current leader of the states, said: "we need to negotiate with him, and the negotiated end to the conflict will depend on him. this is a very important difference, ivanovich, which shows the unpreparedness of the current and the unwillingness of the current."

instructions, so israel will suffer the americans may well force him, but ultimately i am more inclined to believe that they will also save him, but as for these negotiations, i would not make such a big difference between blinken and katsam, because the americans now simply have one very important issue that they need to resolve, this is the release of hostages with dual citizenship, because there are hostages who... and israeli citizenship

is american, if a larger military clash begins in the region, then the fate of these hostages, well, becomes completely bleak, and the democrats need to free these hostages ahead of the elections, yes biden even tried to make a campaign during the exchange with us, and here it will of course be very convenient for him, well, the most important issue that the biden administration and blinken in particular need to resolve is the elections, and the policy of the united states, it is largely determined by the pre-election domestic situation. it was a big game, see you tomorrow, goodbye. hello, this is. the psyche podcast, and we

continue to analyze the most difficult situations , look for solutions where it would seem that they cannot be already and will not be. each of us probably experienced this unpleasant feeling. wasted time on social networks. our heroine today came to us with exactly this request. marina suffers from addiction to social networks. practicing clinical psychologist olga savkin will try to understand marina's situation and i hope to give such recommendations that will be useful to each of us. so, have you discovered that you are addicted? the thing is, i noticed that i wake up. i immediately pick up the phone, fall asleep with the phone, and for a long time i generally i didn't even think that it was somehow wrong, that it was something wrong, i'm not sure now that i can say clearly, i'm sure, i still can't diagnose myself, i can't call it an addiction, this should

be done by a specially trained person, but i can clearly say that the phone and social networks began to interfere with me in everyday life, so let's try... to figure out how this happens, can you describe to us your typical day, i wake up, pick up the phone, go to social networks, scroll through the feed and videos, just to make it faster, faster somehow, i don’t know why, it happens that i’m like this, i need to wash my face, well now, and i go down, sit down on the couch and i’m like, well now another 5 minutes, and again you take out your phone, that is, yes, i continue, i think, now just a little bit more, i wash my face. i sit down again like this now and again i want to sleep and it seems to you that you ’re a little bit relaxed when you scroll through your feed, and the moment is such that of course, when i go to the shower, i don’t scroll through my feed, thank god, but it’s imperative that i have it playing

music or some podcast was on, in general , in silence, it’s really hard for me to stay, that is, as if you envelop yourself with this information...

i really want to ask marina, do you suffer from this or is it a thrill after all, because when you get stuck in the morning, just a little bit now, and your eyes closed, and your body demonstrated this pleasure, what is suffering, actually, i was thinking about this, by the way, about whether i really suffer, and as if, well, in fact, no, it’s really pleasure, joy and so on, but when i understand that it interferes, that is, i can be more productive, i can enjoy myself in a different way, get. pleasure from life in some other ways, can you? in fact i can, but for some reason going to some exhibition or somewhere, it's like when i'm already there in the process i enjoy returning home, well, somehow

i even remember, again all the time thinking about the fact that damn, i took some pictures and filmed there, it would be cool to edit it like this now, that's how it is and it will gain so much of everything there. that is, it's always like this red line in my life is present, but i understand that the thrill from some of these deeper things than just clickable all these things, it is longer, and it really is somehow, well, i don't know, you can feel it, but it's the easiest and fastest, for me , if i'm stressed or there, well, i don't know, always, if i feel good, if i'm sad, if i'm happy, that is, it's always social networks, marin, please tell me, and the problem? which is interfering, if we imagine for a second that it is no longer there, just no longer there, and what will happen in life then? well, i don't know, the first thing that comes to my mind is that i am outside the information field, i will not be able to find out anything about my,

for example, the same acquaintances, i will somehow be outside the trends, i will not find out, i will not catch, and if we assume that everything remains as it is , we came to the program today, you had a great time, you got some new, and joyful hormonal reinforcement, i posted a lot of stories from here right away, naturally, of course, well that's it. all the needs of our modernity have been closed, and nothing happens further, and what will happen then if you don't solve this problem, what will happen to life further? most likely it will just be very monotonous always, that is, i - in general, if you remember, well there the past week, the past two or three weeks, morning evening definitely always begin and end the same, in fact, that 's exactly it. diversity and precisely this moment that you are wasting your life, it's very scary, it turns out that it seems

always, that it is endless for us, we probably don’t think about the fact that this can happen, well, that it is given to us as if for a limited period, and well, further, besides the fact that later you just regret that you didn’t do something or couldn’t remove some, well , some, as it would seem, nonsense, but which... takes up a huge amount of your daily life, takes up a huge amount of time, well, you don’t want to just sit, watch and think, god, can i ask you, marin, now, when you give your speech, could you to appropriate to yourself what you are talking about, this means i position, that is, i am letting something through not from the position of you, yes, as we are accustomed to the generally accepted forms of speech, through you, right when i begin, maybe it will become... from the third person, or we are talking about someone, this is some kind of disconnection from yourself,

life in general, because if we say i position always helps us to appropriate our own , which naturally does not cause an emotional reaction in us, which gives us that very decision that we need to make or that very one. that is, it is as if it is not about me, i sympathize with someone from a distance, maybe even as an intelligent educated person, but this is not with me. here, probably, is a short version of the answer to the question: what will happen to your life if everything remains the same, only from my position, i will screw it up, firstly, talentlessly, yes, everything will pass by, and absolutely, well, in fact, i will feel 100% unhappy. and 100% i will think about what the hell, why, well, sometimes, well, somehow, if you remember,

there are literally events there 3 years there in a row you spent on something, i spent, i spent on something, that now i 'm sitting here, thinking, why and i don't want, well, there are social networks, if i understand that i'm in about the same story as 3 years ago, why do i need this, if in the end i don't know in... how much, but i'll look back and say, well, how was it possible, when the weather is so beautiful until 2 o'clock in the afternoon on a weekend to scroll through the feed, if it were possible to go out for a walk, everything is fine with you, please go, have fun and all that, but everything i'm like, well, yeah, right now, right now just a little bit more, just this little bit more, just a little bit more and i just don't want the moment to come later when this little bit... has already ended, and i'm left like this in this

position, yeah, and what's the worst thing to miss? my own realization, really, oh, how so, and it 's happening right now, from morning till night, realization, i wake up in the morning, pick up the phone and think, i need to not miss something, but at the same time i'm afraid of the same thing at the end of my life, did i hear you right. maybe, but there's a nuance, when, well, my profession, yes, that is, i communicate with people and promote something through social networks for them, that is , either businesses or personal brands and so on, when i do this for them, i fully invest with great pleasure, tracking for them just all those trends that i am so afraid to miss, but there is a moment that i have such a desire to do this. with myself, yes, my own, just to realize myself through these very social networks and

the manifestation of something through them, but myself, that is every time i want something, i just go and say, that's it, from today on i'm not just scrolling through the feed, i'm working on creating content, that is, i'm giving it, not consuming it, as soon as i say this to myself, anything happens to me, i'm oh, it hurts a little bit, god, now we'll... time will pass, oh, i'm still there, that is, it's as if, i don't know how to explain it in reality, but as soon as i need to make the decision that i want, i just really, really strongly.

or something consciously, as if some deep biochemical processes rule us at this moment. thank you for the question, it basically contains the answer. of course, this is a very beautiful, tasty story with defamine. dopamine is a neurotransmitter and hormone, which actually helps us feel pleasure and helps to achieve the next neurotransmitter of the hormone serotonin. joy, defamine was once evolutionarily given to us so that we could focus, collect our body, show some kind of reaction and get ourselves, well, at least food or water, yes and enjoyed it, remember, when you're thirsty, when you drink, what are you, what are you doing at that moment, yeah, oh, how good, that's how good, that's

exactly what dopamine addiction is, in fact , because yeah. we very - quickly due to - if we 're talking about physiology, due to bright pictures, due to the rapid change of some information, very superficially, though, we need to mention this, because everything that you and i quickly flip through is stored only in short-term memory, in the long-term it's not nothing remains from the word zero, that is , after sitting in some feeds for 7 days in a row, we cannot remember what was there? we cannot remember 5 days ago, but at the same time we constantly maintain a certain level of joy in ourselves due to this neurotransmitter history, due to dopamine and naturally, receiving positive reinforcement, we need even more more more, because this is called tolerance, when we have

a certain set of such quality of good pleasure for ourselves for... fear of being left without a phone, is called addiction, by the way, now there is already a name nomophobia, it's a pity that this is not yet in absolutely yes, that is, this is a behavioral classification of diseases, and we cannot officially begin to treat it yet, but i assume that our forecasts in this sense are quite positive, soon we will have something to do. japanese green macha tea is wonderful, its beneficial properties, as well as other important and interesting things for your health, friends, in the program live, great, tomorrow on the first, in banana-lemon singapore on sunday on the first. this is

a psyche podcast, and today we are helping to understand the problem of addiction to social networks with psychologist olga savkin. look, what does this all remind me of? it reminds me of an eating disorder. well, tell me, it seems so, yes, how can it not, i know from my own experience, but i, like many girls, yes, especially during periods of stress, anxiety, of course, i start snacking, overeating and not sticking to any regime, yes, and you get it when you go to the refrigerator, hop, yeah.

half a day has flown by instead of a park or an exhibition, all the same this shameful pleasure not only remains, probably, gives more and more of that very dopamine release that olga tells us about, of course, this is in fact quite often such compulsive behavior, this is an obsessive idea to do something, for example, to eat deliciously, yes, or to get into social networks, but ... when it comes to eating behavior, i have some real fear, i will get up, let's say, a certain size, i will not be able to wear some beautiful things and so on further, there you can either fence off with diabetes, for example, it is very good to logically unwind from our examples with you, which we clearly see, well, that is, you mean that a person understands what it is leading to

, therefore he can, he can stop, because he understands what it is leading to, yes, but well, that is, moreover, what can be felt, of course, naturally, well, that is, i have a neighbor valentina petrovna, she ate a lot, this happened to her, here is a real example, and what will happen to us if we do not get out of social networks, or an alcoholic afraid of drinking himself to death? for example, afraid, yes, or freezing there in the snow, in a snowdrift, well, at least some horror stories, but here it turns out there are no horror stories, well, yes, it even turns out, here is the moment to screw up life, you still can’t do it, well, well, somewhere viktor frankol is crying, yes, who would be very useful now in this search for the meaning of life, yes, but in general this worries you very speculatively, yeah, but here i have already noticed in this conversation there is absolutely definitely a...

and now i am trying to compensate for it somehow in a very fast and convenient way, and this will be the illusion of recognition, i have some of my own goals, ambitions and this was in my childhood, when likes, comments and all the rest were not yet in my memory, now, when i understand why i need to do certain actions specifically for myself, and not for the client, i just lack regularity.

as a person completely different, how to say by the nature of dependence, that is, someone can really be the same as our heroine with childhood, here is looking for this recognition

of applause of the stage, yes, someone is simply filling the void, someone is fencing themselves off from something, but maybe there are some universal tips, we will try to derive some kind of formula for quick self-help for a person who, just like our heroine , realized. that something is going wrong, yes, something is too, i am too attached to this pastime, yeah, what could it be? any addiction is an altered consciousness, this means that i am not in this moment, not in reality, and i left reality, and the first, most basic technique is to return to awareness, this means asking yourself the question, what am i doing right now, what am i doing? yeah, i'm not washing the dishes again, this is what we are used to telling ourselves from the point of view of not what i'm not doing, but what am i doing at this moment, i'm looking at

social networks, yeah, what am i doing, what am i doing, and this question can be repeated to yourself so many times that we do not come to the final understanding, what am i doing now, this is a very interesting chain, in fact, it turns out to be very deep, and ... so in the end in at the end, when we got this answer, you can ask yourself the question, am i wasting my life right now or not, yeah, yeah, that's it, but she should want to ask herself this question already at this moment, when she is absorbed, for example, in short videos, of course, naturally, how to do this, write yourself i don't know, a piece of paper, that you woke up in the morning, and you saw this, of course, in fact, if we knew now the final target picture, yes i want to come, in fact, well or not i want to come, but marin, you want to come, yes, it would be easier to build the route, of course, is like a gps point that we set as the final one, or we get into a taxi,

we say, oh... please take me to such and such an address, if we don't tell the taxi driver the address, he'll drive us around in circles, making money off of us, yeah, in the end we 'll just waste a lot of time, we'll never get to the final point, because we didn't tell him, so if we know our gps point exactly, we can build a route there, how far away this point should be, this point should be on today, today, for example, i look at social networks not for work, there is nothing more...

go back, go back, and what do i want to get 10 years ago, and another 10 years ago, and another 10, so five times, yes, what do i want, where do i want to be, at what route, intermediate point do i want to stand, then , for example, you and i took 50 years, yes, we built several decades ago, then for every 10 years we build even smaller steps, yes, that is, for now... every year, what do i want to come to here, what do i want come here, and then we get to the day, and what do i want to come to this point to do today, and what do i want, i want to wake up in the morning and be without a phone for exactly 60 minutes, yeah, and if without a phone, then it's like with what do i want to be or with whom, i'm now a pain in the eyes. in fact, there is an answer,

because once i practiced these morning rituals of mine, it brought me great pleasure and resources, and i really left the house with the idea that i would now simply move mountains, the world and well again these were always fifteen-minute meditations, but when i set myself the goal of practicing these morning rituals, devoting morning hours specifically to myself... i made a screen recording, woke up, my phone was in sleep mode, i didn’t put it away until this happened, that is, in fact, i turned on the screen recording video, i play meditations, that is, these 15 minutes are just me, this voice and my well- space, then beauty rituals, these are some very basic exercises, very basic some kind of care, well, it seemed very much would, i'm even talking about this now, i

want to ask myself, but why... why aren't we doing this now, what happened? and who are we? oh, it was great just now, we, we, we, who are we? and we, i don't know, i always say that, yes-yes-yes, and how many of you, there are many of us, as we see, well, great, maybe it's just that some role, it's the leading one, who are we? i don't know, it's really difficult, i was discouraged, well, that is, i understand that there is marina, who is helplessly stuck in this endless stream of videos, yes, and there is successful, and this answer, by the way, today - and well, for now, excuse the background, but it's important, in general - while i was walking to the train in st. petersburg, i was talking to my dad, and i was explaining the situation to him, that i'm going to a shoot now, i'm really interested in it and i want to , but i need to skip work for 2 days, and i was so worried, how is this possible, how

can i afford it? although, well, in general, everyone has an adequate attitude to this, and i explain to him, i say, and i scolded myself for this and was so anxious, and then it was as if some other part of me took took me by the hand, said: calm down, and i calmed down, and he says to me: well, how much is this possible, we've already talked about this a hundred times, you can allow yourself to do whatever you want, well, something like that, what a great dad you have, yes, but we really had a situation there again connected with this super-dependent person, where we really united and... started to discuss all this, that is, they support me very much, and i say to him: you know, i just got a metaphor and this is the answer to your question, i say, you know, i have a feeling that there is an adult marina, and there is a little marina, and little marina is constantly doing this nonsense, sometimes the adult wakes up and says, well , calm down, that's enough, that is, roughly speaking , she takes her hand, she doesn't even give a slap on the back of the head , by the way, it's interesting , that is, she doesn't hit her, doesn't scold her, exactly like everything

is fine. let's go with this, if we are talking about we, then most likely this is the answer, yes, olga, do i understand correctly that this is usually what clients are taught, yes, yes, and marina herself?

here, please take the money, it's all my fault, i'm to blame for everything, you take the money, buy a new car or fix the old one, alyona, no, what are you saying, i beg you, just take the money, just don't call the police . this is a psyche podcast, please watch all the episodes of our podcast on the website of the first channel 1tv.ru. i really liked what you suggested to marina, i would like you and i, marina, to try to bring this to some kind of maximum. olga suggested that

you imagine yourself at some kind of peak point, here when you have achieved some kind of your maximum happiness, or some kind of success, or a mission accomplished. can you right now together with us fantasize and imagine what it will be like, for example, in 30 years, let me speak for you, well, for example, you have become a very successful producer, you have been invited to speak in front of a huge-huge audience, students, young leaders, yeah, you go out in front of them, they start applauding you, when you haven’t even really opened your mouth yet, there are huge screens behind you with your... photos, with your presentation, i 'm going to faint now, that's what i want, but not the producer, yeah, yeah, and you say, you know, friends, 30 years ago, on about the same morning i made a decision for myself that i

wouldn't look at the phone screen for more than 10 minutes an hour, that's how my success story began, i feel freedom, i don't know how to explain it, what you... just what comes to mind, i feel freedom, i feel some kind of moment, phew, yeah, hurray, i did it, i got there, yeah, well finally, wow, and it's not in in that sense, finally, i've been this way for so long, that 's exactly it, by the way, it's as if you even helped me find the answer to the question, why do i need a hut, that's what we started with, where did we start, why should i get rid of social networks? yeah, it's as if i have answers right now, i really like it, and can you describe it exactly what, here you are standing on this stage, i practically even saw the color of the clothes, i really want to check, do you know what fashion will be like in 30 years, or what? no, i can imagine imagine, just based on the expectations

that are broadcast to us on social networks, yeah, yeah, what kind of scene are you on? so, well, first of all, i have a healthy weight, and super, so, yeah, i have a different hair color. it's light and kind of closer to mine, but not exactly mine, but closer there, so, well, my hair is still long, about the clothes, by the way, i can't imagine the style and so on, it's definitely not red, yeah, that's for sure, what are you, i look expensive, tasteful, without any kind of conventional blackness, i feel, i feel very confidently. i want, i want, well, really, i want to enter into a dialogue with people who are there now and i want to share something useful, but i can’t say what, but i want to

enter into a dialogue with them, and so that it would be useful to them, i am proud of myself, i am grateful to myself for the fact that 30 years ago, yes, i am grateful to myself for the fact that 30 years ago i took myself... hands could mm, well, how can i say that i now control my life, control my presence in the social field, in social networks.

somehow you were able to turn some switch in your life, okay, we will be pleased in 30 years, very much, i would like to share a few recommendations that seemed universal to me, here , olga, i am interested in your opinion, what do our colleagues advise us, how can we help ourselves reduce our dependence on social networks, first, try to turn off notifications, well... when you know, such announcements come that a new message has arrived,

some channel has been updated, then you need to determine a time limit for yourself, for yourself, and strive for it, maybe it won't work right away, but nevertheless, a cruel measure, marin, to delete the application from social networks, that is, only on the computer, when you get to the computer and sit down, i understand that it hurts. but nevertheless, advice that i don't know how to follow, it sounds like this: keep yourself busy, well, that is, keep yourself busy with something else, grow flowers, chat on the phone, and i don't know, vacuum, probably, something like that, come up with your own reward system, well, for example, an exhibition or a ticket to a concert or a new dress, well, something like that, i think that each person can have their own reward system, you just need

to think about it. a few more pieces of advice: never carry a mobile phone, do not take a bathtub with you into the toilet room. psychologists advise this, they draw conclusions, apparently, based on some - in general, researched situations. find someone who will support you - a partner, a friend, a girlfriend, a sister, a brother, a husband. they said slyly, well, will your life change

tomorrow morning? well, i wanted to say, i hope, but i just have a feeling that i i'm sure that yes, oh, and is it possible without i have a feeling, just shorten the route? i'm sure that it will change, because i've now come to the realization that yes, it turns out that it's not difficult, and most importantly, and finally, we, well , first of all, i felt out, why do i need this. yes, what we actually started our dialogue with you with, with what and for what, is it necessary at all, i think that it is necessary. i have one question, it seems to me, it will be very appropriate. marin, how could you answer, and what will i do right today, in confirmation my intentions? i answered this question to myself literally a few minutes ago. i already thought about the fact that i 'm going home today, here. to the hotel, and usually, when i go, i do it like this, and today i realized that

i have my big bag, which i arrived with, i'll put my phone in there, get into a taxi and go like this, a great plan, friends, and i wish for all of us, let's at least start with this, that today, when or tomorrow morning, when we'll be getting ready for work or maybe during the day, well, in general, in the nearest trip we will hide the phone at the very bottom of our bags. or in the most secret pocket, jacket or blazer, we will try to live a few minutes of withdrawal at first, and then i am sure the pleasure of the fact that life is not ... and certainly not in the phone. this was the psyche podcast. hello, this is the baden baden podcast, and i am

its host konstantin severinov. today we will talk about genetic diseases, oncology, especially about genetic diseases of children. our guest is mikhail mashchan, doctor of medical sciences, professor, director institute of experimental and molecular medicine, dima rogachev children's hematology center. hello, mikhail. hello, konstantin. we have statistics, they are as follows. every year in russia , approximately 3,500, from 3,500 to 4,000 patients fall ill with oncological diseases. keep in mind that hematological and children's are all tumors, these are all tumors, all pediatric oncology is 3,500 patients, 3,700, to be precise, but our area of ​​interest also includes patients with hereditary blood diseases and hereditary diseases of the immune system, what is called hereditary

immunodeficiencies, yes, these are diseases in which the immune system stops working as a result of some kind of breakdown - at the level of the genome, yes, a breakdown, most often inherited, that is, in total, the number of patients annually who, well, are included, or something , in the area of ​​interest, the center, in the area of ​​our competence, this is about 5-600 people, at what age can the debut of such a disease occur, here the question is a little broken down, because when we talk childhood cancer or oncological diseases in children, we are talking about several dozen, at least... maybe several hundred different diseases, yes, and for each there are statistics, but if we talk about the most common tumor in children, this is acute lymphoblastic leukemia, this is a tumor of cells that were going to become cells of the immune system lymphocytes, but along the way there was a failure they turned into a tumor, so for

acute lymphoblastic leukemia, what is called, well, the peak, if you like, of the incidence occurs at the age of 4 years. but a child can get sick immediately after birth at 18 years old, and you said that it is hereditary, that is, these are children of parents who are already sick, why, why does this occur at all, why at 4 years old, why not right away, first is the cause of this tumor hereditary, and the answer, unfortunately, is not entirely clear, i would say, rather no, yes, that is, if we take all patients with acute leukemia, the proportion of patients with a hereditary predisposition.

but there are genes that seem to predispose to the development of a tumor, these genes are transmitted from generation to generation, that is , a separate gene, that is, you and i do not have such a gene, knock on wood, but someone else does, maybe you and i have such a gene, or rather, we are talking not about a gene, but about some kind of polymorphism, yes, that is, about a gene variant , some kind of amino acid replacement, which works a little differently, that is, it is a damaged version of the udorov gene. such a gene also exists, but in people with a predisposition or sick people, it is slightly changed, and you know what these changes are, you generally need to know, if a patient comes to you, what is the cause of his genetic disease? yes, of course, the answer is yes and yes, because, firstly, there are breakdowns that greatly affect the behavior of the tumor, yes,

there are mutations that make the tumor insensitive to conventional therapy, well, here is the simplest example, a very well-known oncology gene, not only in pediatric oncology, but in adults there is such a gene p-53, yes, which codes for a protein that controls cell death and the cell's response to genetic damage, so if such a damaged version of such a gene is inherited, then firstly, the patient has a much higher risk of developing various tumors, including because in this case, cell death

was born as a surgical specialty, but pediatric oncology is, of course, far from only surgical, because most tumors in children, or most of them, are tumors originating from blood cells and the immune system, and these tumors most often do not grow in one place, they cannot be removed surgically, they most often immediately, well, in some sense, we can say that this is the fourth stage, yes, if in simple language say, that is, they are widespread. throughout the body, and to cure them, surgery is not just not enough, surgery does not work here, and drug therapy is necessary,

now methods of immunotherapy are appearing, therefore, well, i am more of a hematologist by education, an oncologist, yes or there is such a field of medical oncology, where non-surgical methods are used, but drug drug treatment, but i must say that here there is such a ...

to look or check the state of the gene? well, historically, these were very simple, or rather, when these methods appeared, they did not seem so simple, somewhere everything...

any oncological disease is genetic in nature of the breakdown, and i still remember, sometimes there are some phrases that you do not need to read the whole book, sometimes it is enough to read the title there, so i still have in my head such a phrase from a book that you should be more familiar with there was such a book - alberts, molecular biology of cells. and there at the very end there was a subchapter dedicated to -