hello and welcome to bbc news. i'm lukwesa burak. we start in the us, where five people have been charged over the drug—related death of the friends star matthew perry. the 54—year—old actor was found dead in a hot tub at his los angeles home last year. he had taken ketamine. those charged include the actor's former personal assistant — two doctors who are accused of supplying the star with the drug — and a woman known as the ketamine queen. court documents allege matthew perry's assistant injected him more than 20 times with ketamine in the days before he died. emma vardy reports from los angeles. hey, i got you a present. oh, my goodness, where did you hide it?! to fans, matthew perry, best known as chandler bing,

was the funny character from friends who'd made no secret of his flaws. he'd struggled with drugs and alcohol throughout his career. i'm in control of the first drink and so i do all these things to protect myself from not having the first drink. at the time of his death, he was said to have been undergoing therapy for depression, taking small doses of ketamine. but when he was found in the jacuzzi at his home, the levels of the drug in his body were much higher. the five people facing charges are alleged to be part of a criminal network supplying the drug, including two doctors, who used the actor, say law enforcement, as a way to make money. these defendants took advantage of mr perry's addiction issues to enrich themselves. they knew what they were doing was wrong. they knew what they were doing was risking great danger to mr perry, but they did it anyways. the desperation that led perry to these individuals was not met with help as it should have been from the doctors,

but instead it was met with exploitation. exploitation by those have should have guided him towards help. matthew perry was charged $2,000 for a dose of ketamine worth around $12. the doctors are accused of acquiring the drug and falsifying medical records. one of them, writing in a text, "i wonder how much this moron will pay?" and matthew perry's personal assistant has admitted injecting him on the day he died. investigators say while looking into the actor's death they uncovered a drug supply network involving a dealer known as the �*ketamine queen�* in hollywood and say other suspects in connection with the operation are continuing to be investigated. let's cross live to los angeles to speak to our north america correspondent peter bowes. hello. what sort of reaction has the latest development in the story received in the

united states?— the story received in the united states? ., ., united states? the word that i kee on united states? the word that i keep on hearing _ united states? the word that i keep on hearing is _ united states? the word that i keep on hearing is sad, - united states? the word that i keep on hearing is sad, how. keep on hearing is sad, how very sad this situation is. matthew perry, our beloved actor and notjust beloved actor and not just beloved because actor and notjust beloved because of his role in friends but beloved because the way that he dealt with his problems. he was very open about his addictions, he wrote about his addictions, he wrote about it, he wrote about in his book and a lot of people had really hoped and thought that chapter in his life was over. but clearly not as we heard from this news conference that he had fallen back into addiction, resulting in him getting involved with this group of, we heard of the five individuals including the two doctors and the sequence of events that essentially led these doctors, and alleged supplier of drugs, to enable matthew perry to continue to use kata mean in high and clearly dangerous volumes and

we know from the postmortem that it was high—volume of kata mean in his system that led to his death. the latest on this is that of the five individuals, three have pleaded all acknowledge that they will eventually plead guilty as part of plea deals leaving to, one of plea deals leaving to, one of the doctors, the woman known as ketamine queen to appear in court in the last few hours, they both appeared here in los angeles, by the pleaded not guilty and will be back in court for the next stage in the legal process at some point next month.— legal process at some point next month. ., ~ , next month. 0k, thank you very much for that. _ let's speak to alan schatzberg, professor of psychiatry and behavioral sciences at stanford university school of medicine. hello, there and welcome to the programme. ketamine, what is and how does it work in

treating humans because there's this understanding that it was so strong that it was purely for the veterinary profession? it was developed as a visionary medicine for but an airy and anaesthesia and developed and used as a common anaesthesia agent, in surgery. and also used for chronic and severe pain often due to cost sonoma. the drug was found, somewhat certain issues by serendipity to be an effective, are rabidly effective ingredient that has a number of ketamine clinics around that provide ketamine for patients, someone with pain patient, some of in depressed patients, there are guidelines with how to use it, there are guidelines about the doses, the

common doses to use. we've been involved in funded studies to help look at the proper dose of the academy and so it can be used —— ketamine, the issue really becomes into what it is used in none of the proper supervision is if the patient is given the ketamine to self administer and have somebody else administer them, the doses can be getting out of hand, individuals can become addicted and that seems to be the case here with this case where there was a history of addiction for which they were undergoing active treatment. i5 which they were undergoing active treatment.— which they were undergoing active treatment. is the issue then that _ active treatment. is the issue then that the _ active treatment. is the issue then that the access - active treatment. is the issue then that the access to - active treatment. is the issue then that the access to the i then that the access to the ketamine, it's been described access and use of ketamine in the united states described as the united states described as the wild, wild west. what is the wild, wild west. what is theissue the wild, wild west. what is the issue in terms of controlling it and ensuring

that we don't have a similar tragic death occur?- that we don't have a similar tragic death occur? well, the dru: is tragic death occur? well, the drug is approved _ tragic death occur? well, the drug is approved by - tragic death occur? well, the drug is approved by the - tragic death occur? well, the drug is approved by the fdal tragic death occur? well, the i drug is approved by the fda for anaesthesia and is commonly used for pain. the use for depression is what we would call off label so any drug in the us, pretty much that is approved for one indication can be used by a physician to treat another disorder. generally, under bark by, you know, some clinical trials, extensive case studies and etc. it becomes somewhat difficult to have some of these agents when the physician has access to prescribing them, there are other individuals who, in fact, prescribed ketamine to be compounded orally by a compound

pharmacy in the us and then, they are given to the patient and they have more and more problems with that because some patients will get into difficulty because of they have relatively free and open access to the drug. relatively free and open access to the drug-— to the drug. 0k, professor, thank you — to the drug. 0k, professor, thank you very _ to the drug. 0k, professor, thank you very much - to the drug. 0k, professor, l thank you very much indeed, thank you very much indeed, thank you. to the middle east, where israeli political leaders — including benjamin netanyahu and two far right ministers — have condemned a large group ofjewish settlers who went on the rampage in a village in the occupied west bank, setting houses and cars on fire. the settlers — some wearing masks — were armed with batons, rocks and molotov cocktails as they descended on the village ofjit. at least one palestinian was killed and others seriously injured. it comes as gaza ceasefire

talks are due to resume in qatar today, after what a us official has described as a constructive first day of discussions on thursday. israeli representatives are attending but hamas — which runs gaza — has stayed away accusing israel of changing its terms since previous rounds of talks. a hamas official also reiterated that, "any agreement must achieve a comprehensive "ceasefire, a complete israeli withdrawal from gaza "and the return of the displaced." on thursday, the hamas—run health ministry reported that the number of palestinians killed in gaza has passed 40,000 — although israel disputes the figure. later, the families of israeli hostages still held captive in gaza following hamas' october the 7th attacks, gathered to demand a deal to secure their release, with several thousand marching in tel aviv. mohamed taha, from bbc arabic, is with me in the studio.

i wonder if we could start of first, please, with doha, all eyes on doha and the ceasefire talks, what can you tell us about where we are with that? good morning. there is optimism in the talks in doha at the moment, there are statements from john kirby, the communication of the security adviser in the white house saying that they are not discussing the structure of the deal but they are discussing the details of implementing the deal so this is really advanced the stage because hamas was saying, we're not going to discuss a new deal, there are — there were already proposals from president biden before and those in security council in resolution and we shouldn't be discussing a new deal and the

statements from john kirby and resuming that negotiations from yesterday to today means that there is some hope and i think that american diplomacy succeeded to shift the attention from the expected iranian retaliation from their soil to this hope for the success that successful negotiations this time. and meanwhile, _ negotiations this time. and meanwhile, how— negotiations this time. and meanwhile, how are - negotiations this time. and meanwhile, how are things in gaza, israeli bombardment is continuing and the ——as the talks take place in doha? {iii talks take place in doha? of course this has never stopped. khan younis witnessed some bombardment and there is fighting there, evacuation decrees to israel to some areas and as you said in your introduction, this is the violence even expanded to the west bank and not in the hands of the israeli army but in the hands of the settlers and there are some palestinians dying and

the exchange of fire between hezbollah and israel and the north so all of these operations are happening and all eyes are on the talks in doha as the famines of 40,000 people died in gaza and the families of more than 100 hostages in israel are really looking for these talks to succeed, for the children to return to their schools, for the people to return back to their homes, for the people to have the opportunity to find medical care, for this water and and for the piece to come back to the middle east. qm. back to the middle east. 0k, thank you — back to the middle east. 0k, thank you very _ back to the middle east. 0k, thank you very much - back to the middle east. 0k, thank you very much indeed. here, the government has set out details of a compensation scheme for victims of an infected blood scandal dating back to the 1970s. some may receive up to 2.5 million pounds — or $3 million — after what's been described as the worst treatment disaster in the history of the nhs. more than 30,000 people in the uk were infected with hiv and hepatitis c after being given contaminated blood products. there's been a mixed response to the compensation plan from campaign groups

as our health editor, hugh pym, reports. they'd call for years for truth and justice and campaigners who gathered in may two the publication of the public enquiry report felt that had been delivered. it said the scale of this cancer was horrifying and that doctors of the nhs and government had repeatedly failed patients. today, more details of the final compensation package had been published, payments to those infected will start by the end of this year and to those affected including families, sometime next year. existing support schemes will continue as well as compensation. about 3000 people so far had been in touch with the official poly running the scheme but it's not clear how many will claim. it

scheme but it's not clear how many will claim.— many will claim. it is important _ many will claim. it is important that - many will claim. it is important that the i many will claim. it is - important that the support schemes to continue because that gives financial security to our community and it is in and poured in recognition of past loss, its separate compensation because compensation because compensation is a recognition of the damage that was inflicted on the whole community through treatment, even to them by the nhs. earlier plans from the government had been assessed by the head of a new compensation authority, sir robert francis, his back most of them and suggested changes. this include extra payments to those who are subject to scientific trials without consent. that was what happened to some peoples at the special cool smack school in hampshire which had a unit to care for haemophiliacs. they receive £15,000 extra as well as compensation. but they say thatis as compensation. but they say that is not nearly enough. i think the £15,000 is both the rogatory and not only to the

children but to others that died but also the families. i really — that — without really words, i cannot believe it. find words, i cannot believe it. and those infected _ words, i cannot believe it. and those infected with _ words, i cannot believe it. and those infected with hepatitis c or lost loved ones because of the virus are concerned and earlier consent — make suggestions that compensation will be a lot less than those infected with hiv. no update on that has yet been announced. minister said it was an important milestone for victims and campaigners and everything possible would be done to deliver compensation quickly. campaigners that will be anxious to see more of the detail. hugh pym, bbc news. around the world and across the uk, this is bbc news.

the world health organisation says more cases of a dangerous mpox variant are likely to be found in europe in the coming days, after sweden reported the first infection outside africa.

it says the person was infected while staying in an african country. a growing outbreak of the illness prompted the who to declare a global public health emergency on wednesday. simonjones reports. in the democratic republic of congo, the country hardest hit, public health campaigns are under way to warn people of the dangers of mpox. 0riginally known as monkeypox, it's transmitted through close contact such as a sex, skin to skin contact or breeding close to another person. it causes flulike symptoms and skin lesions. they often clear up within a couple of weeks but mpox can be fatal particular for people with weakened immune systems. for people with weakened immune s stems. �* ,, �* for people with weakened immune s stems. ~ ,, ~ ., systems. translation: three of my children _ systems. translation: three of my children and _ systems. translation: three of my children and i _ systems. translation: three of my children and i were _ my children and i were infected. 0ne my children and i were infected. one was treated here and the other taken to hospital. after two weeks, they

were discharged and a week later, my wife was infected. aha, later, my wife was infected. a case of the more dangerous strain of mpox has been recorded in sweden. the authorities say the person became infected during estate in an area of africa where there is currently a major outbreak. it there is currently a ma'or outbreak.�* there is currently a ma'or outbreak. , , , outbreak. it is very probable that we will _ outbreak. it is very probable that we will see _ outbreak. it is very probable that we will see more - outbreak. it is very probable that we will see more cases| outbreak. it is very probable i that we will see more cases in europe so it's important for all to be aware that this can happen. all to be aware that this can ha en. ., , all to be aware that this can ha en. . , :: happen. there had been 450 deaths in _ happen. there had been 450 deaths in the _ happen. there had been 450 deaths in the democratic - deaths in the democratic republic of congo following an outbreak of the new strain, it also be detected in neighbouring countries including the central african republic, uganda, can you, rwanda and burundi. the surge of m ox rwanda and burundi. the surge of mpox in _ rwanda and burundi. the surge of mpox in the _ rwanda and burundi. the surge of mpox in the democratic - of mpox in the democratic republic of the congo and a growing number of countries in africa, constitute a public health emergency of international concern. who is warning about the potential of this mpox virus to spread further across countries in africa and possibly outside the

continent. , ., ., continent. this doctor from the uk health _ continent. this doctor from the uk health security _ continent. this doctor from the uk health security agency - uk health security agency said... 0utbreaks 0utbrea ks can be 0utbreaks can be controlled by preventing infections with vaccines, the uk government says it had stopped piles as part of its preparedness plans, the world health organization says a co—ordinated international response is now vital. simon jones, bbc news. to japan, where hundreds of flights and bullet train services have been cancelled, as another typhoon approaches. typhoon ampil is expected to skirt the tokyo region, home to almost 40 million people, before heading up the pacific coast. it comes days after tropical storm maria dumped record rain. let's speak to journalist, james simms, whojoins us from tokyo.

how concerned how concerned are how concerned are people with typhoon ampil moving in? this how concerned are people with typhoon ampil moving in? as you mention, typhoon ampil moving in? as you mention. it's _ typhoon ampil moving in? as you mention, it's not _ typhoon ampil moving in? as you mention, it's not going _ typhoon ampil moving in? as you mention, it's not going to - mention, it's not going to directly hit tokyo which is probably one of the largest metropolitan areas in the world. but it's coming during the holidays where we have tens of millions of people that are travelling back to the homes and now they are coming back at the end of the week and as you mentioned, over 600 flights have been cancelled and hundreds of bullet trains have been cancelled as well. so those bullet trains over 200 miles an hour between the two main natural areas of a sucker and tokyo and those have been cancelled so people are having to scramble alternatives as well as possibly additional lodging. well as possibly additional loduuin. ., well as possibly additional lod..in_ ., ., , well as possibly additional loduuin. ., , well as possibly additional loduuin. ., ., , ,, lodging. how does this season com are lodging. how does this season compare with _ lodging. how does this season compare with those _ lodging. how does this season compare with those in - lodging. how does this season compare with those in the - lodging. how does this season l compare with those in the past? it looks to be a fairly normal season but one of the issues is

that the sea temperatures are a bit higher in the past few years so there are concerns that even if the frequency is not increasing, the strength of the typhoon is increasing and is current typhoon is considered to be a very strong typhoon on a scale of one to three so we have a possible wind gusts of up to 134 miles an hour and so this is the strongest typhoon that will come close to tokyo in about three years but about five years ago, there was a lot of damage from one of the typhoons that knock down the power transmission towers and so in some parts of the outskirts of tokyo, there were people without power for days. h0??? tokyo, there were people without power for days. how is ja an set without power for days. how is japan set up — without power for days. how is japan set up for _ without power for days. how is japan set up for national - japan set up for national disasters that are not earthquakes? we know the buildings and structural aspects of japan are very well adapted to the earthquake risk and threat, what about things like strong winds? the

typhoons?— like strong winds? the typhoons? like strong winds? the hoons? , , , , typhoons? the biggest issue with the typhoons _ typhoons? the biggest issue with the typhoons is - typhoons? the biggest issue with the typhoons is that - typhoons? the biggest issue with the typhoons is that in i with the typhoons is that in additions to wind damage blowing off rooms, there is flooding and so over the past five or ten years, they've actually changed how they announced the potential for flooding because people were not heeding the warnings and people ended up getting washed away or drowning and there was one incident, about five or six years ago, where air retired person flooding and dozens of people died and so they've actually started to improve the evacuation procedures for people that are at risk and for example, in the current typhoon, the government, east of tokyo, evacuated people because of the flooding. but they've also made the warnings much stronger to ensure people heed warnings of flooding. thank you very much for that. the duke and duchess of sussex have been welcomed to colombia

for a 4—day tour of the south american nation. harry and meghan are being given a full security detail throughout their visit — which has been dubbed a diy royal tour. colombia's vice president, francia marquez, said she was inspired to ask the couple to visit after being moved by their netflix documentary. ione wells has more from bogota. prince harry and meghan markle may not be working royals but they still got a pretty majestic welcome on their first visit to latin america, they are being hosted here in columbia by the vice president, francia marquez, she and a couple seem to have a couple of things in common, both of them have talked a lot about one thing, to protect children from online home, including things like cyber bullying and harassment so a lot of the events that the couple took part in on theirfirst events that the couple took part in on their first day events that the couple took part in on theirfirst day in colombia were various kind of summits, panels, discussions with activist, with experts in

the field of online safety particular protecting children on the internet and protecting children's mental health. now they also did visit a school where they spoke to some primary school children about how social media impacts our lives and they also work and privy to a bit of colombian culture, they were — the audience for the indigenous dance and music performance which they then took part in extensive in the end, they took selfies with some of the performance, this is part of the four day trip entitled to colombia. as i said, there are no longer working royals, that here in their own capacity to promote their own sort of charity work and campaigning to stop but this is the second international visit like this in just a few months, visiting nigeria and it's interesting because they have spoken openly about their fears about doing such high—profile events in the uk because they worry about threats that they received online, they worry about the fact that they are no longer entitled to government funded security a way they were when they were working royals. so,

this international events suggest that perhaps overseas campaigning is where their focus is now turning. stay with us here on bbc news. hello there. the summer holiday season is in full swing, and if you have plans for the weekend, well, it looks likely that the weather is going to behave itself. it will be largely dry, sunny and pretty warm. now, we have got a little bit of rain clearing away from the south and east as we speak and this area of low pressure to the far north—west. that's at risk of driving in a few isolated showers, chiefly to the north—west of the great glen, and here, a brisk wind with it as well. but elsewhere, a lot of sunshine. any early morning residual cloud will ease away from the kent coast. the sunshine break through and temperatures should peak between 15 and 20 degrees in the north, highs of 25 in the south. that comes at a cost if you are

a hay fever sufferer. certainly across england and wales, we are likely to see high pollen levels through friday afternoon. but as we go into the start of the weekend, we'll have clear skies across england and wales. still a bit more of a breeze and a few isolated showers to the far north—west. but that means during the early hours of saturday morning, under those clear skies, temperatures will fall away to single figures in a few spots. so a slightly fresher, more comfortable night for sleeping. but we've got high pressure building in from the south and west, quietening things down. again, that low to the far north could still drive in just one or two isolated showers, but on the whole, it's a dry picture for many of us through the weekend. we will be chasing cloud amounts around, particularly with that south—westerly wind. some cloud lapping onto west—facing coasts. here, not quite as warm, but these temperatures are where they should be really for this time of year, ranging generally from mid—teens in the north to the mid 20s in the south. then on sunday, scattered showers are likely to be continuing into the far north and west,

maybe one or two through the irish sea — very fleeting, few and far between. we keep the sunshine for most. and once again, if you are planning any outdoor activities, the weather should behave itself then into next week. there is a potential for weather fronts to push its way into the far north—west. just how much rain we'll have in the south—east corner is really subject to question. here is where we're likely to see the driest of the weather, but a little more unsettled further north and west, and as a result, not quite as warm. take care. bye— bye.

us democratic presidential nominee kamala harris is set to unveil her economic plan on friday. as the premier league kicks off we take a look at the money generated by the sport. and what do you get if you mix a restaurant and a night club? well, a �*clubstaurant�* of course. we explore the idea that's trying to revive london's nightlife. live from london this is business today. i'm lukwesa burak. the us democratic presidential nominee, kamala harris, is set to unveil her

economic plan on friday. the economy and the high cost of living have been a key issue for voters — something both harris and republican nominee donald trump have addressed in their campaigns. 0ur north america editor sarah smith reports from maryland. along the shore of the chesapeake bay it cost more to eat out than it did before. marilyn's famous scrubs and seafood have increased in price, lowjust about price, low just about everything price, lowjust about everything else in america. so it may look like the living is easy, but people are still worried about inflation. who do you blame for the crisis was loi you blame for the crisis was l0| blame the democrats. yeah? i believe the policies are hurting the workingmen. they get paid by the hour. so to get up get paid by the hour. so to get up and work every day you think you have to do that to get the american dream. just know it is getting harder. american dream. just know it is getting harder-— getting harder. every three da s getting harder. every three days they _ getting harder. every three days they have _ getting harder. every three days they have to - getting harder. every three

days they have to go - getting harder. every three days they have to go to - getting harder. every three days they have to go to the grocery _ days they have to go to the grocery store and