live from london, this is bbc news. hezbollah retaliates after reports that at least ten people were killed in an israeli strike on a residential building in lebanon. venezuela's opposition leader tells her supporters she will not give up her protest against president maduro�*s claim to have won the election. matthew perry's death brought medical use of the drug ketamine into the spotlight. we ask an expert what people who use it are hoping to achieve. hello, i'm lauren taylor. we begin in the middle east, where lebanon says at least ten people were killed in an israeli strike on a residential building in the southern city of nabatieh. the lebanese state news

agency says two children were among those killed. israel said it was targeting a his brother weapons depot. lebanese media say they have fired more than a0 rockets into northern israel in retaliation. israel says it was more than 50. also on saturday, hospital officials say an israeli strike in central gaza killed at least 15 people. they say a house and warehouse sheltering displaced people were hit. wyre davies reports from jerusalem. images and reports from across the region show there are still huge obstacles to peace, despite the positive messages coming from talks in qatar. in gaza, an overnight israeli air strike reportedly killed 15 people in the central area of the palestinian territory. although israel said it had eliminated a number of armed fighters, several women and children were also reportedly killed. translation: what happened is that, around 1:00 in the morning, _ three rockets hit directly the house of this man and his family. there were many children and women inside, mainly women, around 20 in total.

to the north, deep inside lebanon, the israeli air force said it had also struck hezbollah targets, including a weapons storage facility. but reports from the scene said at least ten people were killed, many of them syrian refugees, including a woman and her two children. translation: this is an industrial area, a brick factory, _ slaughterhouse, metal factory, aluminium factory and cow farm. it's an industrial and civilian area. there's an urgency for the next round of talks to succeed, amid fears that the conflicts in gaza and either side of israel's northern border could escalate into a much wider regional war. but hamas officials have already dismissed american optimism as an illusion. president biden has welcomed the reported progress in the qatar talks. i'm optimistic. not far from over. just a couple more issues and i think we got a shot. are you more optimistic now than you have been in months past?

yes. why? if i told you that i'd give away what's going on. l his secretary of state, antony blinken, is heading to the region to promote what is being called a final bridging proposal, hopefully leading to a ceasefire in gaza and the release of hostages in exchange for palestinian prisoners being held in israeli jails. wyre davies, bbc news, jerusalem. as the fighting continues, so do ceasefire and hostage release talks. israel's team is reporting cautious optimism. our senior international correspondent, orla guerin, is following developments from beirut in lebanon. she gave us this analysis on the negotiations. a hamas spokesman said that the americans were excessively optimistic and trying to buy time and that the proposals hamas had received four mediators were very disappointing. we know that the two sides have been

given a bridging proposal, an attempt to close the gap between them. antony blinken will come back to the region next week in cairo and will have another round of talks. i think a point is going to come, and possibly quite soon, where all of these frenzied international efforts, frantic efforts to get a deal together, cannot be sustained in the absence of any real, tangible progress. neither israel nor hamas will want to be blamed if there is no ceasefire, but mediators fear we are coming to a cross in the road where it is either a ceasefire is agreed or there is a very real risk of all—out regional war. venezuela's opposition leader, maria corina machado, has called for both nationwide and international demonstrations, urging people to protest against president nicolas maduro's disputed election victory last month. she addressed supporters from the back of a truck in caracas, saying that she would not abandon her protest. a group of united nations experts

said that venezuela's presidential election lacked "basic transparency and integrity". experts have criticised venezuela's national electoral council for declaring the incumbent, president maduro, the winner without publishing detailed voting tallies. on friday, the organisation of american states, meeting in washington, adopted a resolution, calling on venezuela to publish comprehensive details of the results. alfredo romero is a venezuelan human rights lawyer. he spoke to us from caracas about the risks protesters were taking. we have verified more than 1,400 detainees, which are being detained in protests, the mass protests that have happened, in those 15 days before now. and we verified and are identifying different situations happening injails. so it is an important risk because repression is being used effectively,

as you said, to crack down on protests. what recourse do people have if they are arrested? there are many things happening at this point. the problem is that we don't have access to detainees as private lawyers. right now, the families... they have been incommunicado for about 15 days. families have had access and they are reporting things. a guy yesterday, there is a guy in a specific prison centre who has beenjailed there. there are minors, people from 14—17 years old. we have verified 126 minors 14—17 years old.

there is one girl named victoria who is part of the system in venezuela. she is a musician. this massive repression, the results are that everyone that is walking on the street is being detained, even if they don't participate in these protests. people are very scared right now. a lot of relatives of these children are totally scared, i cannot say what the expectation of people are, but i am totally sure that people are waiting for a peaceful solution of this situation. of course, there is a political issue, there is also political expectations, but at this

point our major focus is on solving this humanitarian problem that is going on right now. with people in jail and actually what happened is a reaction to protests, for example there are protest today and the reaction of the government is repression and effectively they have been using repression in order to stop protests, and repression means that people are being killed and jailed, etc. the ukrainian military has released video which it says shows the destruction of a key bridge inside the kursk region of russia. this video shows large explosions on the structure, about 11 kilometres from the border, in an area of kursk that remains under russian control. moscow says a bridge was destroyed on friday. russia says it is pushing back the ukrainian forces, which have captured territory in its kursk region, but ukraine's president zelensky says his forces are strengthening their positions.

the russian authorities are continuing to evacuate civilians in areas near to where the fighting is taking place. according to local officials, more than 3,000 more people have been moved to safer areas in the past 2a hours. the fighting also continues inside ukraine. these pictures show the aftermath of what ukraine says was russian shelling of the city of sumy about 35 kilometres from the border with russia. two people are said to have been injured. and we have one other set of images to share with you. ukraine released these pictures of what it says was the moment its forces crossed into russia into the kursk region on the 6th of august — the beginning of their incursion. they appear to show a heavily damaged border post and no further resistance from russia forces. james waterhouse is in the sumy region with more on the significance of ukraine destroying this key bridge. well, it seems that what ukraine is looking to do, alongside drawing in russian troops, is also control its logistics or frustrate supply lines. so we saw, as you saw there,

in quite spectacular fashion, a major bridge crossing in the north of the kursk region. it goes over a river that flows into belarus, and that had been used by russia's military to previously feed its invasion of ukraine. but ukrainian forces also control a number of major highways from north to south, connecting to the belgorod region of russia further south, which had been used by russian forces as well. and notjust that — the town of sudzha, which ukraine has captured, is on a hill, so it is allowing ukrainian forces to control the battlefield in that respect and force russian forces to react, and that is costing them men and machinery. ukraine will be suffering losses as well, but at the moment it's ukraine doing the dictating. and while its advances are slowing, what kyiv will point out is, look, we might be making a kilometre a day, that is still more than what the russian forces are making in a day

in eastern ukraine. but, crucially, those russian forces are still moving forward. it's not going to be easy, and i think we just need to look at recent history as to why. the same general who came up with this counteroffensive is a guy called 0leksandr syrskyi, he is now the head of ukraine's armed forces. he was responsible for these counteroffensives in 2022, which blindsided russia. he used misdirection by talking up offences elsewhere, and he used the element of surprise. the moment when things turned south, went badly for ukraine, is when the fighting then slowed — it became static and that favoured russia and its greater size. so we've seen that again, haven't we, in the kursk region? they've moved in, they are expanding at quite a rate. they've taken quite a lot of territory very quickly. but russia will gradually divert more and more resources to slowing that advance. and once you have defensive positions firmly in place, which russia has been building, then that really will be a test for ukraine.

and also it will present it with a difficult decision as to when, when or if it should pull out because losing men is something ukraine can especially not afford to do, unlike russia. the un's atomic energy agency says that the nuclear safety situation at ukraine's zaporizhzhia power plant is continuing to deteroriate. the nuclear station has been occupied by russian forces since shortly after the invasion. it has occasionally been damaged by fighting and a un team says there has been intense military activity in the area over the last week. that includes a drone explosion just outside of the plant, near to the essential cooling water sprinkler ponds. the director general of the international atomic energy agency, rafael grossi, said he was extremely concerned that there had been another escalation of security dangers at zaporizhzhia. when friends actor matthew perry was found dead in a hot tub at his los angeles home last year, it seemed to have been an accident.

he had been treating depression with ketamine and no foul play was expected. but the arrest of five people including medical doctors, perry's assistant, and an alleged dealer, shed light on a suspected, underground distribution network — and cast doubt on the use of ketamine to treat depression. rachel feltman — who is a sciencejournalist, specialising in psychedelic drugs and ketamine therapy, i asked about the prevelance of ketamine use in therapy. it is definitely exploded in recent years. back in 2021, i wrote a feature for a couple of science museums about the use of cat men in my own experience using it as a treatment for ptsd, and at that time i estimated there were 75 clinics offering it in the us. 0ne outlet has now estimated it is closer to 750 clinics so there has been in surge the demand in it. explain to

us what it does _ surge the demand in it. explain to us what it does to _ surge the demand in it. explain to us what it does to humans. - surge the demand in it. explain to us what it does to humans. it - surge the demand in it. explain to us what it does to humans. it has| us what it does to humans. it has been used as a sedative for humans as well since at least the 19705, and that it is what it has the approval for. and that it is what it has the approval for-— and that it is what it has the aurovalfor. �* , , ., _ ., approval for. but it is very easy to net it approval for. but it is very easy to get it off label _ approval for. but it is very easy to get it off label as _ approval for. but it is very easy to get it off label as is _ approval for. but it is very easy to get it off label as is the case - get it off label a5 is the case with many drugs, which sometimes it is one of many psychedelic drugs being researched for their potential to treat depression in humans, but in terms of what it does, it is known as a dissociative anaesthetic at a5 a dissociative anaesthetic at very high doses. at lower doses, it can induce anything from relaxation to meditation or transcendent 5ea, into an actual hallucinatory state as well. . , into an actual hallucinatory state aswell. . , , ., ., , as well. clearly, the investigations

have found — as well. clearly, the investigations have found that _ as well. clearly, the investigations have found that their _ as well. clearly, the investigations have found that their investigation j have found that their investigation may have uncovered a broad underground criminal network of drugs 5upplier5 underground criminal network of drugs suppliers who distributed large quantities of ketamine, you said it is used off label, how easy is it to obtain it now? that said it is used off label, how easy is it to obtain it now?— is it to obtain it now? that is an interesting _ is it to obtain it now? that is an interesting question _ is it to obtain it now? that is an interesting question because i is it to obtain it now? that is an - interesting question because people are views ketamine recreationally and illegally for as long as it has been used as an anaesthetic, so the use of ketamine a5 a recreational drug in high quantities and illegally i5 drug in high quantities and illegally is not new, what is new is it is easy to access it through these clinical settings and a5 it is easy to access it through these clinical settings and as you said, these are lower doses than matthew perry had in his system, the doses that matthew perry wa5 matthew perry had in his system, the doses that matthew perry was getting from these people were truly like an order of magnitude, higher than what you see in traditional therapy.

the london fire brigade says a fire that broke out at the historical somerset house is under control and final checks are being made to ensure it doesn't reignite. london fire brigade say 20 fire engines were deployed when plumes of smoke were seen coming from the 18th—century arts centre on the banks of the thames. there were no reports of any injuries. speaking outside somerset house, keeley fo5ter, deputy assistant commissioner of the london fire brigade, provided an update on the fire. just before midday, the brigade took the first of over 30 calls reporting a fire at somerset house. 20 fire engines and around 120 firefighters have been working since then to bring the fire under control and protect this historic landmark. the fire was located in part of the building's roof space. the age and design of the building proved a challenge for crew5 as they initially responded. as a result, four of the aerial

ladders including a 64—metre turntable ladder were deployed to support firefighters as they carried out a complex and technical response. this included creating fire breaks in the roof, which has now limited the spread of flames. 0ur correspondent, noor nanji, was outside somerset house with more. well, the london fire brigade, as we were hearing there, said that they first received reports about this fire at around midday. crews were sent to the scene and have been tackling the blaze ever since then. and as we just heard there, they are still working to extinguish the final pocket of the fire and the cause of the fire is not yet known. now, when i arrived here several hours ago, there were thick clouds of smoke. you could see it several 5everal 5treet5 away and you could also see it in some of the social media videos that have been posted of the fire, including over the river thames. the building itself had been evacuated and there were no reported injuries. we also know that the artwork

is believed to be safe. now, don't forget, somerset house is an historic institution. it dates back centuries. it is now used as an arts venue. it is home to the courtauld gallery, which houses 5everal priceless pieces of art, including by van gogh and monet, amongst others. but we were speaking to the director of the somerset house trust, who told us that the area in which the fire broke out, that was actually different to where the artwork is housed. so those concerns have been allayed. but as you say, the efforts are still going on to contain this fire. and for now, somerset house remains closed to the public. 0pening weekend of the premier league, 5ix 0pening weekend of the premier league, six games on saturday, arsenal have started their campaign with a win at home to wolves, the arsenal manager says they should have scored more at the emirates. kai havertz got the opener. and bukayo saka added a lovely second

after the break, a trademark finish from him, cutting in5ide from the right, beating the wolves keeper at his near po5t. right, beating the wolves keeper at his near post. i right, beating the wolves keeper at his near post-— his near post. i think we should have opened — his near post. i think we should have opened a _ his near post. i think we should have opened a gap _ his near post. i think we should have opened a gap in _ his near post. i think we should have opened a gap in terms - his near post. i think we should have opened a gap in terms ofl his near post. i think we should i have opened a gap in terms of the scoreline much earlier. but then we showed great consistency later. and we had some giveaways which were tricky. we had some giveaways which were tric . �* ., ., we had some giveaways which were tric . 1, ., ., , tricky. bournemouth came from behind to draw 1-1 at — tricky. bournemouth came from behind to draw 1-1 at nottingham _ tricky. bournemouth came from behind to draw 1-1 at nottingham forest, - to draw 1—1 at nottingham forest, chris woods gave forest the lead in the first half. the match was stopped for ten minutes early in the first half with fore5t'5 brazilian danilo treated on the pitch after breaking his ankle. he danilo treated on the pitch after breaking his ankle.— danilo treated on the pitch after breaking his ankle. he has broken his ankle, breaking his ankle. he has broken his ankle. so _ breaking his ankle. he has broken his ankle, so it _ breaking his ankle. he has broken his ankle, so it is _ breaking his ankle. he has broken his ankle, so it is serious, - breaking his ankle. he has broken his ankle, so it is serious, going l his ankle, so it is serious, going to miss him, not only on the pitch but he is a wonderful boy, he is

always smiling, always with joy, wishing the best. i think is leaving the hospital wishing the best. i think is leaving the ho5pitaljust now and then he will be assessed tomorrow and after tomorrow, but it is too serious but the good news is he is stable, he is speaking and aware, so just need time. speaking and aware, so 'ust need time. , ., , ., ., , time. there is a winning start as liverpool's _ time. there is a winning start as liverpool's new _ time. there is a winning start as liverpool's new head _ time. there is a winning start as liverpool's new head coach. - time. there is a winning start as liverpool's new head coach. the time. there is a winning start as - liverpool's new head coach. the new brighton manager also had a win in his first game, 3—0 at everton, a5hley young sent off, newcastle beat southampton, joe linton with the goal, an aston villa one against town. major leagues acro55 the goal, an aston villa one against town. major leagues across europe are getting acro55 under way, psg won on friday while in spain, they have been going a few days now and started the season on thursday. that finished 1—1. barcelona are about to

kick off at valencia, they finished ten points behind real madrid last season. real have strengthened their 5ea5on. real have strengthened their team as well with the arrival of kylian mbappe and barcelona's new boss knows the size of the task. when i signed my contract here, i know it is not so easy, but i totally trust and believe in the club, but at the moment i am happy with this. with what the team shows. when you see all the injured player5 when you see all the injured players we have out, i think we had a really strong team. we have out, i think we had a really strong team-— strong team. that was the opening da , inter strong team. that was the opening day. inter milan — strong team. that was the opening day, inter milan conceded - strong team. that was the opening day, inter milan conceded in - strong team. that was the opening day, inter milan conceded in the i day, inter milan conceded in the 95th minute, drawing genoa, palmer also drew with fiorentino, other two matches are half an hour in, milan losing at home, emboli and monster are goalless at the moment. there is

are goalless at the moment. there is a one—shot lead going into the women's open. she is top of the leaderboard on 12 under, her compatriot a shot behind, the german and england's charley hull are two shots further back. brandon mcnulty has the leader's read jersey at the tour of spain which starts in portugal this year, the america was fastest on the first stage, time trial through the streets of lisbon and leads the race by two 5econd55. lot5 and leads the race by two 5econd55. lots more on the bbc sport website, but that's all for now. india's health ministry has urged doctors to return to work after they caused non—emergency hospital services across the country to be shut down because of a 24—hour 5trike.

the industrial action was part of ongoing prote5t5 following the rape and murder of a colleague in kolkata a week ago. tens of thousands of people have demonstrated in city 5treet5 across the country, demanding justice. the assault on the 31—year—old medic has reignited national outrage at the chronic issue of violence against women. the most recent statistics show 445,000 crimes against women in 2022. on average, that's about 51 crimes every hour. among those, there were 31,000 rape5 reported or, on average, one rape is reported every 16 minutes. 0ur correspondent, archana shukla, has more from mumbai. now the largest doctors' grouping, which is the indian medical association, hasjoined into the protest. so, today, 24 hours of nationwide 5trike. the first such where both government as well as private health care institutions will stop all non—emergency service5. so all your elective surgeries as well as outpatient departments in both government and private

hospitals will be closed today. and that is a mark of protest and literally amping up the protest to put pressure both on the investigative agency as well as the government to do more about safety. we know that the top crime agency is investigating the incident of the rape and murder of the 31—year—old trainee doctor in kolkata, and protester5 are trying to amp up more and demand that a speedy trial and justice is given in that matter. and they are also demanding that the government come up with stricter laws to make it safer at workplace. like we heard from one of the protesters that they spend hours together at the hospital, that's literally like their second home. and if they are not safe even there, then where can women be safe? and, you know, despite laws having come into place, they are not effective on ground. most of the protesters who i have spoken to over the last few days have told me that there are laws, but they are not effective

and hence they are demanding that the government come up with one, a central law that can protect doctors against any violence that is levelled at them and, secondly, is to also make it more saferfor women at workplaces and outside. you know, despite laws, violence against women has only gone up if we go by the government statistics over the last one year, it has gone up by 4%. and this is something that the politicians, the government and the public all need to sit up and take notice of. and finally, a cargo spacecraft has arrived at the international space station to deliverfood, fuel and other supplies for those on board, including two nasa astronauts stuck there for several months. the unpiloted spacecraft successfully transferred about three tonnes of supplies. two nasa astronauts, butch wilmore and suni william, are stuck on the international space station because of safety concerns over the boeing starliner capsule. they were originally expected

to return home after eight days. stay with us here on bbc news. good evening. although the sun wasn't out for all of us today, we did have a good deal of dry weather and that's the way it will continue this evening. if anything, the cloud may break up to reveal a little bit more sunshine and hopefully there'll be a bit more around tomorrow, but there'll still be a few showers. we've had those pushing through on the brisk wind in the north and west. that continues this evening. the odd one elsewhere, even possibly in east anglia and the southeast, where we've had the lion's share of the day's sunshine. the cloud melts, though, through the night, the winds ease further and it'll be another coolish start on sunday morning. perhaps a little bit of fog if you're up early enough because actually the winds are falling lighter through sunday as the azores high ridges closer to our shores, but still that westerly breeze in the north. although a notch down on those of today, the winds, there's still enough to carry a few showers in, possibly the odd one. northern ireland, northern western parts of england and wales.

but after the morning mist, it should be a largely dry, bright day with good spells of sunshine. it will feel pleasantly warm, as it did during the day today. temperatures mightjust be a degree down in the north, but with lighter winds, that will compensate. however, it is all change as we go through the new week, so high pollen levels again through monday, as you can see. but into the new week, we've got wind and rain coming in. monday, i think, mostly fine and dry. so sunday into monday out of the ridge of high pressure producing some mist and fog across central and eastern areas, possibly further west with some sea fog. but that rain coming in looks quite intense, particularly the second part of the day across northern ireland, western scotland, northern scotland as well. there'll be cloud piling in around the irish sea coast, some sea fog here, but further east we've switched our wind direction, picking up more of a southwesterly, so we could again see temperatures nudging above 25 in some spots. it will be warm for all and a warm night monday into tuesday. warm and wet. as you can see, as that weather system carries its way eastwards

behind it on tuesday. lots of showers, heavy thundery showers during monday night and into tuesday as well because its warm air so we'll still see temperatures in towards the mid 205 in the south and the east, but closer to average further north and west following our rain. but if ijust show you that rainfall as it piles up through the week, mostly in the north and west, but, anywhere, really, seeing some rainfall tuesday. but the heaviest falls likely in the north and west, perhaps cumbria and north wales, with some more wet and windy weather midweek on.

this is bbc news, the headlines. israel says hezbollah fired more than 50 rockets over the border — without causing any casualties. earlier hezbollah said an israeli air strike in southern lebanon killed several people in a residential building. an israeli team has said it is cautiously optimistic about the gaza ceasefire talks. but hamas has described suggestions of progress as an illusion. the venezuelan opposition leader maria corina machado has spoken to a protest in the capital caracas. she promised to continue to try to overturn what she said was nicolas maduro's falsely claimed victory in the presidential election. the ukrainian military has released video of what it says is the moment a key strategic bridge in russia's kursk region was destroyed. meanwhile russia has launched a new bombardment in the border region, around sumy.