hello, welcome to bbc news. palestinian health workers have started vaccinating some babies in gaza against polio, a day before a mass immunisation programme is due to start. palestinian health workers carried out the vaccinations in nasser hospital in khan younis. unicef says the official campaign will start on sunday at 7.30 in the morning local time in deir al—balah. it says the vaccinations will take place for six and a half hours each day until wednesday. israel and hamas have agreed to three localised pauses in fighting to enable more than 600,000 palestinian children to be vaccinated. let's get more on this with our correspondent in jerusalem jon donnison. tell us about the logistics of this vaccination programme.

they have got a lot of young children to vaccinate. 6a0,000. and with the polio vaccination it comes in two rounds, so more thani million it comes in two rounds, so more than 1 million vaccinations are already in gaza, the first round of vaccinations will start tomorrow as part of this campaign, and then in three weeks those children will have to have another vaccination. so, a lot of the logistics around this have actually been about keeping the vaccination is cool because obviously it is very hot in gaza at the moment and they have got to be refrigerated, and for the most part it is local doctors who would be administering it, but with so many people to be vaccinated it is obviously going to be challenging. let's turn our attention to israel �*s military operation in the west bank, what is the latest on that? well, this intensified

israeli military operation has now been going on for several days, and it has continued today, as you say specifically in jenin. my today, as you say specifically injenin. my colleagues there say they have been loud explosions coming from the urban refugee camp in the centre ofjenin, as well as bursts of gunfire. israeli helicopter gunships have been spotted overhead. israel says it is pursuing its counterterrorism operations, its foreign minister has said there is, in effect, a war in there is, in effect, a war in the west bank, and it is a war that israel is determined to win, but it is having a huge impact on civilians living in palestinian cities in the north of the west bank. many of them have been shuttered up in their homes for many days. i was in ozempic this week and it was deserted on the streets. my colleagues injenin say they have seen a number of women and children being brought out in a

group from the refugee camp, but it is an ongoing situation. and there has also been an attack on an aid convoy in gaza. what is the update on that? ~ , gaza. what is the update on that? ~ a, , that? well, this actually happened _ that? well, this actually happened on _ that? well, this actually happened on thursday l that? well, this actually i happened on thursday and that? well, this actually - happened on thursday and it was a convoy from a us aid group that was taking medical supplies to a hospital in rafah, in the south of gaza. what they say is that the convoy was hit by an air strike. the first vehicle in the convoy was hit, and that for people, palestinians, who were escorting the convoy as a security to protect it from looting, died in that air strike. the charity involved says that they were not actually their employees, but they had been recruited

locally. israel has said that they were militants travelling as part of this convoy �*s cover. as part of this convoy 's cover. ., ., ., ~ cover. for the moment, thank ou. we're joined now we'rejoined now a local reporter and we can speak to her now injenin. we had a little bit there about the situation in the occupied west bank but what happened specifically where you are today? yes, there is a block to all the main roads leading tojenin main camp and to the city, and to the west of that there have been strikes injenin also. thus they started to bomb all the electricity generators. they started to destroy all the

infrastructure here injenin. infrastructure here in jenin. they infrastructure here injenin. theyjust infrastructure here injenin. they just cut all the water lines, the connections and internet lines sojenin city and camp, it is like they cut all their connections for people who live there. also they killed 12 people, one of them is an 80—year—old man, so theyjust them is an 80—year—old man, so they just want us to them is an 80—year—old man, so theyjust want us to be afraid. they want civilian people to be afraid. they want to destroy them and stop them from defending here injenin. but defending here in jenin. but israel says— defending here in jenin. but israel says this _ defending here in jenin. but israel says this is _ defending here injenin. but israel says this is very much a counterterrorism operation. what efforts are made to protect civilians from this operation? protect civilians from this operation?—

protect civilians from this oeration? , , ., ., operation? yes, they do not rotect operation? yes, they do not protect the _ operation? yes, they do not protect the civilians. - operation? yes, they do not protect the civilians. they i protect the civilians. they just go to their homes, take them from their homes, prevent them from their homes, prevent them from their homes, prevent them from using their mobile to call an ambulance or anyone to take them back, orjust to take into people also. they started to shoot people in their houses. also they said there is 1000 people in their houses, but they move from one house to another and they do not say anything if there are people there or resistant people there, they start to arrest them. they are lying. until now, or people that have been killed are civilians.— killed are civilians. from jenin, thank _ killed are civilians. from jenin, thank you - killed are civilians. from jenin, thank you for - killed are civilians. from i jenin, thank you for talking killed are civilians. from - jenin, thank you for talking to jenin, thank you for talking to us. brazil has begun implementing a block on elon musk�*s social media platform, x, in a dispute

about the spread of disinformation. the ruling was made after the company missed a deadline to name a new legal representative there. a supreme courtjudge ordered the "immediate and complete suspension" of x until it complies with all court orders and pays existing fines. x removed its legal representative from brazil, claiming thejudge had threatened her with arrest. elon musk says: "free speech is the bedrock of democracy and an unelected pseudo—judge in brazil, is destroying it for political purposes." let's speak now to our colleague daniel gallas from bbc brazil. how is this being seen in brazil? well, this is seen as a huge political issue in brazil. even the president said that the sovereignty of brazil must be respected and he criticised elon musk for his stance on this issue. the wider thing is that there is an issue about

fake news and how it should be dealt with by social media companies like x. basically what the brazilian authorities are demanding is that x takes down a few profiles that they say are spreading fake news. all sorts of issues like election issues, political issues in brazil, health issues as well. x has said it is about freedom of speech and that people should be entitled to say what they want. this escalated a lot when elon musk decided to remove all representatives from x from brazil and close down the officer said that the company would not have a legal representative to answer to the brazilian supreme court ruling. so the answer to that, in reply to that now the supreme court has blocked x across brazil, and their is this division between people who support elon musk and those who support the

justice system. tell musk and those who support the justice system.— justice system. tell us a little bit _ justice system. tell us a little bit about _ justice system. tell us a little bit about the - justice system. tell us a | little bit about the history justice system. tell us a - little bit about the history of this dispute between elon musk and the courts in brazil. elon musk has used some fairly intemperate language about it. yes, elon musk has been criticising this supreme court judge who has made these decisions and there is also a link between elon musk and the former brazilian president bolsonaro, they have been sympathetic between each other, and the judge sympathetic between each other, and thejudge is sympathetic between each other, and the judge is seen as a huge enemy of bolsonaro, and that is how the bolsonaro camp or chase him. in the past, thisjudge has ruled that many times against bolsonaro when he accused the brazilian elections being rigged. so there's this ongoing dispute and this past history that has divided the political spectrum, conservatives in brazil, they

tend to hate this judge. conservatives in brazil, they tend to hate thisjudge. elon musk is gathering a lot of support from these political sympathisers of bolsonaro and the right wing.— the right wing. daniel, thank ou for the right wing. daniel, thank you for talking _ the right wing. daniel, thank you for talking to _ the right wing. daniel, thank you for talking to us. - researchers say they believe a drug used to treat obesity and type—2 diabetes could also help slow the ageing process. studies on the effectiveness of semaglutide, which is sold under the brand names ozempic and wegovy, found that the drug could be used to treat a wide range of illnesses linked to heart failure, arthritis, alzheimer's and even cancer. researchers say that by improving people's health this way, the drug could help slow ageing. we are joined now by professor bryan williams, chief scientific and medical officer at the british heart foundation. thank you very much forjoining us. it sounds almost too good to be true. how does it work, how does it slow down ageing? well, i think what they were really getting at is if you

look at many of the diseases and conditions that are associated with ageing, the common ones are heart disease, stroke, dementia, cancer etc, and when these drugs are being given to patients who are obese or have diabetes, or both of those conditions, and they produce significant weight loss, the evidence now suggests that many of those conditions are prevented to a significant degree and obviously we are excited at the british heart foundation that we see a significant reduction in heart attacks and strokes and hospitalisation for heart failure. when we are talking about significant, we are saying about a third of the cases that would otherwise have occurred are being prevented. so, that's what they mean by the ageing process itself. going beyond that, there has been an argument at the meeting, ora been an argument at the meeting, or a discussion, about whether all the benefit associated with the weight loss generated by these treatments

if that is the main cause of the benefits, or if there are other effects of the treatments themselves. does it produce other benefits independent of weight loss? they come to the conclusion because when they look at patients who don't lose as much weight as other patients, many of those patients, many of those patients are still seeing the same level of benefit, particularly in terms of reducing heart disease and stroke. so, why is it happening if it looks like even in some cases the weight is not coming down very much? i think there are a number of reasons for that. we know that when you are overweight, and if you lose weight, particularly if you lose weight with these drugs, they modify your appetite, not only for food, but it seems like you may reduce your intake of alcohol, and if you smoke you may reduce your smoking habit. so that's a fascinating observation that has come out of many of the trials. 0bviously they would have a major impact on reducing risk.

there is also evidence being presented at the meeting that these injections that induce weight loss also produce significant reductions in blood pressure, and as a consequence of weight loss we see reductions in cholesterol, with the reduced risk of getting diabetes so patients become more mobile and more active. so there are many facets, all of those things such as stopping smoking, reducing alcohol intake, reducing weight, taking more exercise and often those cells will help reduce the burden of cardiovascular disease. the message it reinforces is what we have been saying for a long time, try and maintain a healthy body weight and if you are overweight, try to lose weight ideally naturally by taking more exercise and modifying your diet, but it is exciting that for those patients who tried that and have not been able to get the weight loss they desire, then we do now have a treatment option that looks highly effective at reducing weight, but also reducing the

patient �*s risk of going on to get heart disease or strokes, which are devastating things to happen. that's why there are so much excitement.— much excitement. very briefly, isn't this just _ much excitement. very briefly, isn't this just going _ much excitement. very briefly, isn't thisjust going to - much excitement. very briefly, isn't thisjust going to drive - isn't this just going to drive up isn't this just going to drive up demand, critically for people who don't need it as much as some patients whose health really is compromised? well, that has always been the issue with these treatments because some people like to use them simply to try to lose weight to improve their appearance, as opposed to needing to lose weight because they are at risk of heart disease, stroke, kidney disease and other diseases that are caused by weight gain. in some way we must try and target these therapies to those patients who are genuinely overweight above levels that are recommended, or have diabetes, or both. not only is it going to be more effective at reducing weight in those patients, it will be more effective at reducing their risk because they will be the people at risk, and they other people at risk, and they other people who are going to benefit most in terms of reducing heart

disease and stroke.— disease and stroke. professor brian williams _ disease and stroke. professor brian williams from _ disease and stroke. professor brian williams from the - disease and stroke. professor| brian williams from the british heart foundation, thank you for your time. heart foundation, thank you for your time-— now it's time for a look at today's sport. hello from the bbc sport centre. we'll start with football and after a flurry of late activity in friday's transfer window, the attention is back on to the pitch. arsenal announced the signing of raheem sterling on a season long loan from chelsea last night. they're now hosting brighton in the premier league's early kick off. both sides came into the match with two wins out of two from their opening games. it's approaching full—time at the emirates where it's i—i. kai havertz gave arsenal the lead late in the first half — but they've had declan rice sent off and soon after joao pedro equalised. a few minutes to go. manchester city continue the defence of their title with a trip to west ham in the late kick off. west ham already had a really

good squad and this transfer this summer brought new players and especially up front they have an incredible strong team. we know about the quality of the city — we know about the quality of the city players and of the coach, _ the city players and of the coach, and the style and their strengths, but we are going to aim to — strengths, but we are going to aim to he _ strengths, but we are going to aim to be able to overcome this very— aim to be able to overcome this very good — aim to be able to overcome this very good team. now at the us open tennis, jannick sinner and iga swiatek are among the players in action later as well as these two britain's jack draper and dan evans. if they progress they won't have to face, the four—time winner in new york, novak djokovic, because he is out. it was the australian alexei popyrin who upset the defending champion, winning their third—round match, in four sets in new york. and novak wasn't happy

with himself afterwards. i have played some of the worst tennis i have ever played, honestly serving by far the worst ever. so yes, playing on a quick service, without the serve and without the ability to win points, many double faults, you can't win. it's the first calendar year since 2017 that he has not won a major. next to the paralympics in paris — with more medals won on the track on saturday in the women's 5000 metres, t54 final, catherine de brunner of switzerland, took the gold, in a parlympic record time of 10:a3.62, ahead of her american and australian rivals. while in the men's 1500 t46 final, the defending champion alezander iaremchuk was the winner. originally from st petersberg in russia, he's in paris competing under a neutralflag, finishing ahead of athletes from australia and france.

mercedes' lewis hamilton led a closely packed field to finish fastest in final practice ahead of the italian grand prix in monza. hamilton led a mercedes one—two just edging out team—mate george russell. earlier on it was announced that 18—year—old andrea kimi antonelli will be hamilton's replacement at mercedes next year. the italian�*s debut for the team in friday's first practice didn't go to plan for as he crashed george russell's car. he wasn't injured, but it meant russell missed almost half an hour of second practice because the team were repairing the damage. and england's cricketers have extended their lead beyond 400 runs against sri lanka on the third day of their second test against sri lanka at lord's. joe root�*s hit a half century. that's all the sport for now.

some breaking news to bring you now regarding the notting hill carnival, which took place last weekend. the metropolitan police are saying that a young woman who was stabbed at the carnival that she was attending with her young child has now died. she was 32 and she had been taken to hospital for treatment for those injuries following the incident at the carnival. there were a number of stabbings at the event and a great many arrests, it has to be said. some of the people who were injured suffered very serious injuries, as we now are seeing with this 32—year—old now having died after attending the notting hill carnival with her young child where she was stabbed. we will bring you more

details when we have them. websites selling tickets to 0asis' first tour in 15 years are warning the hundreds of thousands of fans still queueing that availability is now "limited". tickets went on sale on saturday morning and people have been reporting technical problems. some fans reported being kicked out of line, meaning they had to rejoin at the end of the queue. one of the providers, ticketmaster, says the queues are still moving. have you got a ticket, christine? yes, we were really lucky to get a ticket last night in the ballot so we are going to the wednesday wembley gig- going to the wednesday wembley . i ., . ., . going to the wednesday wembley ~|~.~ ., ., i going to the wednesday wembley ~'~.~ ., ., lam gig. who are you taking? i am takin: gig. who are you taking? i am taking my _ gig. who are you taking? i am taking my daughter. _ gig. who are you taking? i am taking my daughter. she - gig. who are you taking? i am taking my daughter. she has. taking my daughter. she has never seen them before which is really exciting, and a friend

who is from university, we both went to see them at knebworth in 1996 so it will be a stroll down memory lane for the two of us. it down memory lane for the two of us. , ., down memory lane for the two of us, , ., , ., down memory lane for the two of us. , ., , ., ., us. it will be a stroll down memory _ us. it will be a stroll down memory lane. _ us. it will be a stroll down memory lane, but - us. it will be a stroll down memory lane, but it's - us. it will be a stroll down| memory lane, but it's also going to be a rather different experience. take us back to the previous time you saw them. i have seen a race is quite a few times between 1994 and 1996, —— 0asis, but my first ever gig was at a small venue in leicester, the prince charlotte. i interviewed noel gallagher before the gig, and i had to get out of the gate pretty quickly because it all went mad. it is a cake that he cites as being his second most memorable gig of his entire career because he realised that they were going to be making it big that night, and it was an incredible night. very small, £4 a ticket in those days as well. , ~' ., £4 a ticket in those days as well. , ,, ., . ,, well. yes, i know the princess charlotte _ well. yes, i know the princess charlotte from _ well. yes, i know the princess charlotte from my _ well. yes, i know the princess charlotte from my time - well. yes, i know the princess charlotte from my time at - well. yes, i know the princess| charlotte from my time at bbc radio leicester. it was great for watching up and coming bands. this is going to be very

different. to what extent do you think it will be better or worse in a giant venue with so many people around you? i saw them at knebworth, _ many people around you? i saw them at knebworth, 22,000 - them at knebworth, 22,000 people. the intimacy of a small gig. people. the intimacy of a small gig, for me you can't really beat that. you know, a two foot tall stage really close to the band, and that intimacy is fantastic but i think it's going to be really interesting this time because we are going to see a lot of new fans at the different venues they are going to be playing at, a much wider demographic, and a sharing of people so an experience that people so an experience that people thought we might not experience again. i’m people thought we might not experience again.— people thought we might not experience again. i'm going to ask ou experience again. i'm going to ask you a _ experience again. i'm going to ask you a terribly _ experience again. i'm going to ask you a terribly un-british i ask you a terribly un—british question. ask you a terribly un-british question-— ask you a terribly un-british question. ask you a terribly un-british cuestion. ., . , ., , question. how much did you pay? we were 0k. _ question. how much did you pay? we were 0k, £100 _ question. how much did you pay? we were 0k, £100 a _ question. how much did you pay? we were 0k, £100 a ticket. - we were 0k, £100 a ticket. having said that, that's the first ever 0asis gig i have paid to see because i was a journalist before but i don't mind paying £100 at this time.

i suppose it is time, and they are hot tickets. so your daughter is 26. how long has she been interested in 0asis? she loves all music. i have been playing it to her since she was very small. she has often got on her playlist when we are in the car, so she's listening to them since she was small. she has seen noel gallagher �*s high flying birds with me, and now she will get the expense of the two brothers on stage as well and i'm looking forward to it more for her than me.— looking forward to it more for her than me. great to see her reaction- _ her than me. great to see her reaction. have _ her than me. great to see her reaction. have a _ her than me. great to see her reaction. have a wonderful. reaction. have a wonderful time. thank you for talking to us and well done for getting a ticket. really pleased, thank you. a doctor charged in connection with the death of the actor matthew perry has appeared in court in los angeles after agreeing to plead guilty to one count of conspiracy to distribute ketamine. mark chavez was granted bail but has been barred from practising medicine. his lawyer said he was incredibly remorseful. matthew perry died in october

from a ketamine overdose. another doctor and the alleged supplier of the drug are due to go on trial in the coming months. you might have heard the story this week of a four—year—old boy who accidentally smashed an ancient vase during a trip to a museum. here's how the 3,500—year old pottery looked after ariel geller tipped it over at the hecht museum, in the israeli city of haifa. well, you might not believe this but they've invited him back. ariel, seen here in a blue cap, with his hand being firmly held by mum, was given a guided tour with his family. the museum's curators, who try to display artefacts as openly as possible, wanted to reassure ariel that they understand he didn't do it on purpose. that is one very patient

museum! just before we go, let me bring you some more breaking news regarding the notting hill carnival story that we were telling you about. we already told you that a 32—year—old woman, who was at the carnival with her three—year—old daughter, had died following a stabbing at the carnival last week. the metropolitan police are now also saying that another person has died following a stabbing in the injuries they sustained. this is a chef who used to work under gordon ramsay. he was 41 and he was found unconscious with a head injury outside a restaurant in notting hill in west london. a restaurant on queensway. it was about 11:20pm on bank holiday monday night.

the metropolitan police say both of these people have died from their injuries. there were several others who were stabbed and suffered injuries that meant they had to be treated in hospital, of course, but two people have now confirmed to have died as a result of the injuries they sustained. hello there. it's been a glorious sunny start for most of us to begin this weekend. however, it's not the same for everyone. we do have more cloud around southern and eastern areas, and through the weekend i think we'll start to see increasing chance of heavy showers and thunderstorms, particularly across england and wales. but it's been a glorious start today, like i mentioned. here's a beautiful scene from conwy in north wales. big contrast, though, to cloudier, leaden skies across east anglia and the south east. it's because we're drawing this cloud off the north sea on a fairly brisk easterly breeze across southern areas, whereas further north, we're into the sunny blue skies. so for the rest of the day it does look like it's going to stay rather cloudy across the south and southeast.

maybe a few showers starting to push up from the near continent later in the day. but a warm one to come further north with all the sunshine, low 20s for glasgow. low 20s as well for parts of wales, northwest england. now, through this evening and overnight the cloud starts to drift northwards, start to import some humid air from southern areas and that will increase the chance of some heavy showers or thunderstorm — hit and miss showers, not everyone will get them. but you can see we're importing this warm and humid air from the near continent. so quite a muggy night to come for england and wales to start. sunday could be no lower than 16 or 17 degrees in the southeast. so we start off with a bit more cloud across england and wales for sunday. best of the sunshine towards the north west. but even here the cloud tends to build. there's a chance of seeing some heavy showers and thunderstorms becoming more widespread across parts of england and wales. hit and miss showers, not everyone will get one and there's a question mark to the extent of these showers could be a bit further north, could be a bit further westwards. a warm and humid day to come across central and southern and eastern areas, a little bit fresher further north. for monday, we have a weak

area of low pressure across the country. a couple of weather fronts that will enhance shower and thunderstorm activity, could see some showers and storms across eastern areas. another one in towards the west. again, a bit of a question mark, some uncertainty to the details of monday. have to stay tuned, but could see some sunny spells across the southeast corner and again across the far east, we could be into the high 20s. so again, quite warm here, but generally high teens, low 20s elsewhere with more cloud and showers around. i think as we run through the week, though, conditions begin to improve. we lose the shower and thunderstorms early on, and then high pressure might build back in for the end of the week to settle things down with increasing amounts of sunshine. but stay tuned.

this is bbc news, the headlines... a mother and a chef who were attacked in separate incidents while attending the notting hill carnival weekend have died. the metropolitan police said cher maximen and swedish national mussie imnetudied from their injuries. palestinian health workers start vaccinating some babies in gaza against polio a day before a mass immunisation programme is due to begin. israel and hamas agree to three localised pauses in fighting to enable children the delivery of vaccines. brazil begins implementing a block on elon musk�*s social media platform, x, in a dispute about the spread of disinformation.

a supreme courtjudge ordered the suspension. some brazilians report that their access