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tv   Shift  Deutsche Welle  February 24, 2024 3:02am-3:16am CET

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is this thing waiting for a new hot for a year? will smart technology revolutionize organ transplants, and all 3 d printed organs anywhere close to becoming the norm? find out on shift a hot made from human cells using a 3 d printer signs this intel, if they've already made this breakthrough back in 2019, the printed hot couldn't be yet, but it was a sign that researches were on the right path. the key here is printing using living cells, so called by printing type d printing. well, the other 23 d printing, also known as additive manufacturing, has been in use an industry for a number of years up yet. it basically means building complex objects layer by layer hiding young and a few years ago. and this trend also made its way into the field of biomedicine put us in all the been the hold up in need it unable to is to print the layers of living materials and that's biological material teeth which have very complex material properties in all 50 lives. and for the whole phone,
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cutting the schedule. and so we now have new possibilities. and file medicine complaint can hopefully print complex oregon structures in the future using 3 d by or printing off the file printing desktop at the bottom printing head system. so scientists can actually print organs using living cells. that's pretty incredible. in 2022, the 1st 3 d printed it was transplanted into a volunteer in the united states. but that was the last we heard. we reached out to the company 3 day by a therapeutic several times for an update on the current clinical trial without any luck, but this much is clear the race to manufacture functioning organs using 3 day printers has been going on for years. first attempts to fly printing artificial organs were made over 2 decades ago. one of the trail blazes is us surgeon, dr. anthony atalla. in 2011 a 3 day printed a kidney does the organ is measured using m r. i scanned the daughters then use to
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create a 3 day model which has been sent to the printer. the printer manufacturer has the model layout by layout, from living cells, all as shown here from plus a race such as noting. and trent university develop basically about using a 3 d printer in 2021. it looks deceptively real, but it's actually made of synthetic materials. it's supposed to help train doctors to recognize live it cancer. in 2020 to 3 day systems and united therapeutics presented a 3 day printed long structure. this synthetic creation should help regulate gas exchange, the way healthy lungs do. animal testing should offer insight into how it functions . it will probably still take some time before 3 de printed organs will actually be able to replace traditional organ donations. but this technology is already proving to be very useful in medical research today. like this 3 d printed broad bought a card made from synthetic material. race such as at the massachusetts institute of
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technology in the united states have developed or wrote bought a car using a 3 d printer. the replica is supposed to emulate the functions of a patient's individual heart researches 1st create a 3 dimensional computer model using data from the patients hot. it's made up of the soft, flexible synthetic materials. the artificial heart is wrapped in slaves that mimic a hot date. h one is controlled separately to ensure that it pumps realistically, this way the robotic caught can mirror a hot date of the patient. researches one to hone in on how the patients hot is contracting. robotics is not meant to be transplanted. instead, it's supposed to help doctors better understand the hot conditions of individual
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patients. and therefore i pinpoint the best treatment very helpful for treating people with hot conditions, but not a solution for patients waiting for an actual hot transplant. still 3 day by printing can be deployed in other ways. lots of patients who need a bypass due to block vessels, researches in northern germany, are testing out this idea of vascular surgeon, dr. riven bands and his team of developing a new procedure who's speaking fees isn't in artificial vessels or an age or dream and surgery from the actual a couple of the cardiovascular surgeons. and you inevitably end up in a situation where you're caring for a patient. but don't have any suitable material to use for to bypass. and for example, i must, i'm for hearts bypass or to bypass and the leg researchers have been working for many decades now. i'm creating by artificial vessels in the land. yep. so standing level view, it would enable us to help perform a bypassing patients that don't have the necessary part of the material. i didn't
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expect them to bypass unbeatable to the research team. so idea, a print, a simple tenuously presses to liquids, to create a flexible, to made of bio materials. that's roughly 30 centimeters long. one of these liquids is circled by a when it's a positive organic. think that's enriched with even investigative cells. it's guys, this is an elgin, a material made from brown out of natural back to the sol genay to start so as country the bind well to it. that's why we add peptides, which are small pieces of proteins that can be found in the human body like college and you need to pay the sounds good. now bind to these peptides cubic even the peptides can also send signals to the sales forces so that they feel comfortable and can survive and reproduce and bianca after and initial phase using standard straight print is. the team is now switching to a robot with a specially developed printed one chain. the in the print head contains the boiling
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. while the other contains calcium, fluoride stabilizes the bypass graft. let's look at selective i'm. this may look relatively simple, but it actually requires fine shooting a lot of different barometers and kind of allow the outside on one challenges that bio into it does not have no technic properties. so here's what's missing. in other words, it behaves differently from typical liquids becomes more solid under pressure. but just means we need to equip the printing resistors here to ensure a uniform flow of the by a wink, mcginnis, who move in suppose to you instead of allies. it's all incredibly delicate and precise look. so it's no surprise that the researches have carried out countless test prints. one challenge, the entire structure needs to have a consistent thickness for this evening. but if you take a look at this bypass and you can see how much it sends out within the site, as long as of yes. and on the other 2 sides, you can see that it's quite sick on the inside, right? so it won't hold up on those are the more symmetric, the structure,
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the stronger the circular structure, the more stable it will ultimately be. what was the source of the artificial bypass cross supposed to be as uniform as possible so that they can function inside the patients the decades of the printing, the new structures must mature in a nutrients solution of 37 degrees. for a few days we usually print type room temperature, but keeping the cells at room temperature for a long time can be detrimental to the cells even selling less than the other women . so we print using these supplements. we on the bike and then we place them in san to bio reactive where the culture is kept at $37.00 degrees. the item is for as many cells to survive the printing process as possible. if everything is going smoothly, numerous green cells become visible under the microscope. in the next lab test
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phase, bypass graft a being tested in animals. clearly a controversial ethical issue, but the scientists say it's necessary. and on that topic, 3 d printing with living cells could actually even help to replace animal testing. for example, when developing new drugs, pharmaceutical labs could use so called organ on a chip models. these devices can emulate how human organs function thanks to buy a chips, the need for animal testing could soon be reduced. the cells on so called organ on a chip systems biologically, mimic human, old and when they come into contact with active agents instead of animal testing, researches are increasingly using these kinds of many labs. it helps them to sun, if substances toxic to the human body or whether they could work as medications. the system basically consists of a microscope slide, at least one cell culture and micro channels. the membrane works as
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a carrier for the cell culture, while the micro channels supplied with f, nutrients and active agent pot live. uh, excuse me, cells can be grown onto the chip or printed on the slide. using boiling sensors allowed assign system monitor the condition of the cells home and ship. many bar chains have also started using coaches from multiple organs on the same chip, reducing the number of tests today that are even chips with complex 3 dimensional cell structures, which allows for more precise testing. 3 d printing using living cells, certainly books, very promising. of course, it would be even better if we could print cells and organs exactly where they needed inside the human body. and scientists are already making big strides. check it out. this is an experimental meaning 38 bio for tool could directly print by material onto opens and one day it could be deployed inside the
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human body. we can directly deliver multiple in the lay on the table inside the main body and quite the coloring, melvin, tennessee. they have to make well material outside the body. and then it'll go to the lady, the material to have to be quiet when says read a bunch and read it in quite as last i fiction. and look last similar to an endo scope. the soft, inflexible robeteck is inserted into the body by the through the mouth and a small, a small skin incision using bio ink. the device can print line material on to organs and tissues, for example, to repair them after an injury. so this is a larger version of our 3 d ball printer. we have this is basically use you to, to live up on materials to the engine side or off of the surgery to facilitate to the healing process. we have a camera located at the tip for the visualization,
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as we can see right here. and we have one channel at the top, 2 for the delivery of the materials. and up to fax, we have the control us to control the bending of the printer. and it doesn't lead print, it can also make incisions and spray water to clean the wounds after an operation in the future. this medical tool could be used for different types of surgeries, including the removal of cancer risk. janice, it basically did defy, can utilize on one set of co device that can before them the, and course a big surgical procedure. and therefore we can do more to sit and tie up kinds of timble inside the bodies. i think actually article on kind of sense, there is so much of groundbreaking research going on right now. but what people who are waiting for an organ transplant need the most is more open donors. would you're doing night your organs or do you say 3 day printed organs as the way of the future?
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let us know. and so you next on the one of mankind's oldest ambitions could be within reach. what is it really is possible to reverse the researches and scientists all over the world for you know, race against time. they are peers and rivals with one daring goals to help smart nature. the
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boy likes watching it on youtube dw documentary ice cold b. c. at the end, just to pass it, got any difficult to access an expedition ventures on to places that no one has the why is the ice melting? the the signage research and the i c d w the the the dr. bismark a for a displeasing the g.

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