the, the, this, the dw news line from the berlin european leaders call for an immediate pause in the fighting in gauze of at a summit in brussels leaders from all 27 team members. and demand of the unconditional release of hostages held by whom awesome, they've urged israel not to launch a major ground defensive in the garden city of bravo. i'll say coming up the us secretary of state anthony blinking says negotiators are making good progress towards a ceasefire after thoughts in egypt and leave. lincoln says that he is confident that a deal between is real and so much as possible. he says the gap between the 2 are

narrow, and doctors in the us perform the world's 1st big to human. she'd be transplant, is the latest experiment, and request to use animal organs in human. the bridge off, we have some breaking news coming in. the european union has just called for an immediate humanitarian pause in the fighting in gauze and for the unconditional release of all hostages being held by a moss. it's the 1st joint is you demand for an end due to the hostilities in god's european union heads of government said that safe and full humanitarian access is essential in order to provide light saving assistance to the civilian population inside the gaza strip. alright, let's get to jag,

paris. now he is at that summit in brussels, jack the u, calling for an immediate humanitarian pause in gaza, leading to a sustainable ceasefire. that's a mouthful there. i mean, it all came as a surprise or wasn't it a surprise? this is not necessarily a surprise we had been hearing from most of the e u countries that this was going to be on the cards. but using the word ceasefire has been politically difficult, especially a few months ago. the idea of cooling for any kind of cease fire was looking impossible, but now what we've seen is that the, you leaders have progressively move that position. the dialogue, the needle on the dial has slowly taken towards this coal, which is for immediate to many, many a humanitarian pause, is this is to allow a lot of agents a gaza with the idea of, of this sustainable sci fi in the future. the context of this as well is that a cypriot plan that the united states has not got behind in the last few weeks to

get a through humanitarian aid card or that goes through cyprus means that your p an asset . so, so now i'm moving towards garza and in order for those assets to get in, that's the you is now looking at this situation is some, some way where they need to be getting the aged and to saw cooling for the fighting to stop. and there's a lot going on to somebody tonight. we understand that a decision has been taken on bosnia herzegovina and its application for joining the european union. what we know. yeah, that's right. there's loads going on this. what we've heard from the european lead is, is that the accession team, so the official negotiations will be opened sometime in the future for bosnia and herzegovina. it's still a very complicated situation. they do have to enact some reforms dots within the document, but it is a very symbolic gesture from the european union. they want to make sure that that sort of galvanizing and keeping the support for those western bulk and countries.

so that progression into the you and there is this thorny issue of using flows in russian assets to boost aid to ukraine. did anything happen with that? really? that was the cabinet was cakes much further down the road. d. you said essentially that the discussions on this, on the proposals that have been put forward should be continued to be looked at. and that is something that they could move forward with. that is the context for this. is that around 210000000000 your all of russian financial assets are an e u. financial institutions accruing in for us. i mean that, and some of the leaders want them to be used to support your crime. but at the moment, this is just a discussion that will be ongoing. they haven't made a decision today, you know, some decisions. and so i'm thinking that can provide that that's on the jack parent and brought subject is always think well the gaps are narrowing. that is how you my

secretary of state anthony blinking is describing is real into moss and the possibility of a ceasefire and gossip league and who have been in egypt for talks and thursday. so that's is real needs to do more to help increase the flow of age and to god. so he signaled some hopes saying that he still believes a ceasefire agreement is possible. we can says the gaps in there between is realism off, over the deal. here's the us secretary of state speaking. there's a clear consensus around a number of shared priorities. first, the need for an immediate sustained cease fire with a release of hostages. that would create space to search more humanitarian assistance to relieve the suffering of many people. and to build something more enduring. now, the ceasefire that we're working on would be the best most immediate way to enable us to search mandatory assistance. but it's not the only way. we agreed today,

all of the ministers that we would get our experts together in the coming days to identify the urgent practical and concrete steps the can, it should be taken to increase the flow of assistance is real nice to do more. so how much pleasure are we to van immediate sustain ceasefire is blinking? put it, i put the question to the journalist kareem alga. hari in kyra what you said? basically this is the main way forward. so he said also that that they are getting closer and, but also if we think that the, there has been a lot of difficulties, i had the, i think one of the best indications that there is something with the paper this worst negotiating is the fact that to tomorrow, and that would be a big meeting in do on costa. and also with the head of it is really most of the intelligence service. so there seems to be enough to continue the bushes and

sibling. it seems to be quite optimistic that if we move forward, the kid is set to that. there is more a coming into the last days, but he says it's by far, not enough. and of course, that is a clear call to what's the is re decides to finally open the board has to really get and must, if amounts of age. i think what the say behind it is really that the we just try to spread that some of these and go from there. what for the program that is wanting of and the minute the famine in the cause of stripper and immune and famine is like this. indicate this, the great, the modification number 2, that folks something how many children for the security for tennessee creative, the gaza strip, which it blinks. it also says in the press conference it is 400 percent of the people because so i think the u. s. doesn't want to be complicit any longer into this situation and why? that's why the pressuring for more a to coming in at the it's an indication also that the negotiations been blinking.

ready is where it tomorrow would be quite tough if he wants to move forward. so that was greenville go, how are you there? forwarding from cairo, egypt. the point of me in mars ro hinge of people is again making headlines. after dozens of refugees were rescued off the coast of indonesia, local fishermen and pulled dozens of people to safety. after their boat capsized, the group was sailing. we understand from bangladesh or more than half a 1000000 venture had been re settled. there were a hinge or a minority, muslim ethnic group. persecuted inside me and more liberal hinge or refugees had been stuck at sea for more than a day. until a search and rescue team found them under the beating sun. they had been travelling in a wooden boat capsized after weeks, etc. there were 69 survivors, and no number of people were unaccounted for. just the car was one of the people

found on the boat last night someone was passing by and i asked if we could get into his boat. he said he would call the police. my thoughts help were consumed. but he never came back. some of the ro hinge on board, see their boat held around a 150 people before it think. the group was sailing from bangladesh. in bangladesh, we left where there was a camp for the hinges. is we have a lot of the hinges, live. my whole family is that, but we didn't have enough money. we didn't have enough food. and i couldn't work that. more than half a 1000000 ro hinge a half led targeted violence in myanmar for bangladesh. they lived there and some

of the world's largest refugee camps. some board boats and sailed to indonesia for better conditions. indonesia has welcomed some ro hinge and the past. but some of these tests really be there because of the spike of arrivals, of people trapped and one of history's largest refugee crises did a medical 1st. the surface in the us have successfully transplanted a genetically modified pig kidney into a living human. a man with in stage kidney disease was given the organ at a hospital in boston last week. the organ was especially modified with the crisper gene editing techniques to remove harmful pig genes and to add human ones to boost its compatibility. until now to get these had only been temporarily transplanted into brain, dead human patients. to man have also received p cards. but both died within months like curtis is president mc over in genesis, where he heads,

development of organ transplants between spaces explained health sciences make to keep these suitable for humans. yes, thank you. and thanks for the interest in this and the story. so our approach is really to improve the compatibility of course i, oregon's with human recipients by making 3 different classes of changes to the course. and you know, the 1st group is to remove by what we call androgens are. the molecule is responsible for a per give rejection. we, we, we knock out the genes responsible for those engines and basically eliminate hyper here rejection. the next class of edits are reintroduce human genes into the parts . and you know, in this case we introduce 7 to regulate coagulation compatibility and the mechanisms of rejection. and then the 3rd group of edits are inactive. a indulgence retrovirus is present and of course on geno. and this is to improve organ safety

and avoid the potential for disease transmission from the part time donor to the patient. so in total, we created a total of $69.00 edits into the port sign genome to produce the donor. that was you can just get the transfer and end of the person who received the kidney transplant. how was this patient chosen? because this is a 1st and do we know how the patients doing? oh, yeah, so depressing. and so this patient was the gentleman who had previously had a human kidney transplant that had fail. so he had this transfer for about 5 years in the united states, if you've had a previous transplant. and then you need a 2nd transplant and you're over say 50 years old. it's unlikely that you're going to get a 2nd transplant. so then you're going to dialysis. this particular patient was losing access to dialysis. so he would, once he loses as dialysis, he can't get a transplant. you would have to go into hospice and he would likely pass away. so

this patient had run out of treatment options. and so he was chosen as a candidate for this person or sign to be transplant. and as of today is doing an incredibly well, the poor assign. sidney is being very well tolerated, he's producing urine, his markers of kidney function have improved, and he's on track of to be discharged from the hospital. wow. and so we're very pleased with his outcome. it was so grateful for his is willingness to participate in the study and well and so far, so good and, and it will this patient and thinking about other types of transplants with, with organs it, will this patient have to take medication the rest of his life to prevent any type of rejection of, of the pick kidney. yeah. so he is, he's on immunosuppression. very similar to what any recipient of this you mentioned the would be a plus we've added an additional immunosuppression drug that we referred to as a, a t. so co stimulation blocker from our partner l as on pharmaceuticals,

is developing that for to improve long term outcomes and to reduce rejection. so because on standard of care suppression plus this additional drugs, i mean this sounds very promising, especially for people who are waiting for an an organ transplant to be i understand there are millions of people in waiting lists around around the world. or is this a game changer in your opinion? so we believe it's the 1st step to a major change and how we treat kidney failure. in united states alone, we're looking at about 600000 patients on the houses about 90000 patients out of the transfer a waiting list. the reality is all of those patients could use a kidney in the us. we do about $25000.00 kidney transplants a year, so way under the number that we need to do. so i do believe that this is the 1st step of changing of that math completely. yeah. well, we certainly wish the patient, well, and we appreciate you, dr. mike curtis for talking with this tonight and exciting story. thank you. thank you. appreciate interest. thanks. you watch. the w 9 is coming up. next, we have

a documentary on life in rio de janeiro was for villas, home to migrant gangsters and the defendants of slaves. i will see you here tomorrow. have a good one of the 1000000 people in what it's in just a 100 days. my power is going to be bunch of my family. what cute. how is this age? i'm on a journey to find out about the routes, so the 19 are to put you on the site, but they expect to see the rhonda. my name is some way to shimmer. i'm afraid it makes sweet shaming history out documentary stuffs. april 6th on dw, the .