tv stolitse will next release today in moscow, and we will continue broadcasting for other regions of central russia. russian scientists have created a unique antibacterial drug that can not only stop the development of infection in the body, but also improve the effect of antibiotics, and sometimes eliminate them altogether. these are the cases when, against the background of long-term use of antibiotics, resistance develops, and not simply. stop working, this is where a new drug is especially needed, for which diseases will the domestic drug help? development, ksenia ignatova found out. an ultrasound check is planned today, if everything goes well, we are preparing to be discharged soon. st. petersburg resident maria has been in the hospital for 2 weeks already, she has chronic pyelenephritis, this is an inflammatory process in which the infection affects the kidneys, and it also returns several times a year, with severe pain in the lower back and high. fever, when

there is an exacerbation, when the temperature rises, i feel very bad, i call a doctor, naturally, antibacterial therapy is prescribed antibiotics, and since i have exacerbation three or four times a year, you can imagine how much i drink them, every time doctors have to change antibacterial drugs and make it more and more difficult, the microbes do not die completely, mutate and turn into superbugs, which don’t care about anything, in the end over time , pathogenic... organisms have been identified that are resistant to most antibiotics, so it is necessary to use quite serious antibiotics, massive ones, antibacterial therapy, and for a long time, in principle, for a long time - the patient is in the hospital. such problems are already commonplace in the urology department of st. george's hospital, so it was not difficult to find volunteers to test the new drug developed by domestic scientists. the studies were carried out immediately in dozens of clinics across the country, and these studies were collected. the birthplace of the new medicine in the azen cake

is the gomaley national research center, where they have been fighting viruses and microbes that plague humanity for more than 100 years. the main task of the drug is overcome antibiotic resistance, and to achieve this, scientists have obtained an active... molecule, which has no analogues in the world. it does not kill bacteria, but weakens them, preventing them from multiplying and taking over the human body. the work on creating the medicine took 12 years. we collected clinical isolates, which are now very relevant in moscow hospitals, which have multiple resistance, which are difficult to treat with antibiotics; they demonstrated that all these isolates are sensitive to the action of the developed drug. last month, the medicine

was registered with the ministry of health and in june it should go into public circulation, for now a small batch of only 400 courses. the first batch has already been put into operation, this is happening right here, at the pilot industrial site of the center, this is a full cycle production from the synthesis of the active substance to the production of ready-made tablets. as scientists explain, the drug will reduce the dose.

it will definitely be visible, which provokes predators to disturb human peace year after year - sergei antsigin found out. you know what i love most is when your eyes light up with that special light. come, fall in love, be surprised, be inspired. your moscow.

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pay with your smile with sberpay. via superstar premieres on sunday at 20:20 on ntv. we will continue with you again. the government will allocate about 4 billion rubles to support small medium-sized businesses in the zaporozhye and kherson regions, as well as in the donbass republics. the head of government announced this at an operational meeting with his deputies.

in addition to the two capitals, there is a subway in nizhny novgorod, novosibirsk, samara, yekaterinburg and kazan. alexey prokin i visited the youngest metro in the country, the easternmost and most difficult to create. and learned about problems and prospects. the metro in the capital of tatarstan today has 11 stations,

the electric transport fleet is considered one of the youngest in the country, in fact, like the metro itself, the trains of which set off on the thousand-year anniversary of kazan. since it is the youngest, it was built on new digital principles, here the first microprocessor principles were applied, and not relay ones, as in other metros, and accordingly we have movement today carries out... which brought out to people is not so easy. the kazan metro now works in conjunction with other modes of transport.

transfer hubs have appeared in the city. these are large passenger-generating points where metro stations, trams, trolleybuses, and bus stops are concentrated, combined with suburban railway stations. the experience of integrating the metro with ground transport is being summarized today in novosibirsk. the local passenger transport department has prepared three dozen volumes, as best as possible. in fact, this is some kind of light metro or light rail transport, as it is called, that is, very flexible technologies that we

believe need to be introduced, it is quite possible that our third metro line, maybe it will no longer look like the classic heavy metro, what are the first two lines, perhaps this is something more light rail. now novosibirsk residents use two subway lines, the metro earns 2.5 billion rubles a year, but, according to the director, being at... self-sufficiency, it spends exactly the same amount on repair of trains and infrastructure. we operate already quite worn-out rolling stock, this is probably the biggest problem. of the 100 four cars today, 76 have already passed their service life. the country's easternmost metro has adapted to its geographic location by opening the only repair shop in siberia, where... they not only reanimate worn-out trains, but also significantly extend their life. the mysterious

inscription of mangazeya on one of the stained glass windows of the rechnoy vokzal station, nothing more than the name the first russian city of zapolyari, whose history goes back to glubpikov in 1601, and today workers of the novosibirsk metro expect that the promising metro scheme will not repeat the fate of the forgotten city, because an expansion is planned to improve the transport accessibility of novosibirsk. two operating and the construction of three new lines, but so far the last time metro builders commissioned a new station was at the beginning of 2010, zolotaya niva, the thirteenth station in novosibirsk, the easternmost station in russia, and experts use its example they tell how it is not easy to build a subway in the siberian climate, calling the local metro the most extreme in the world. confidently, today they talk about the integration of the metro with other modes of transport, perhaps only at the bottom. by 2026 ,

a multimodal network, as it is called here, should appear in the city. raised all powers to manage public transport at the regional level, realizing that the city cannot cope, at some point the municipality’s resources are insufficient. now dear passengers of nizhny novgorod are waiting completion of the construction of three new stations, which, as sergei morozov put it, will allow rebooting traffic flows. tunnel boring mechanized complex vladi.

thus, in namsky, flooding was recorded in 16 settlements, this is more than half the territory of the district, about 500 residential buildings were sunk, the water level exceeded the critical level by almost 30 cm, additional forces of the ministry of emergency situations were sent here, the work of the operational headquarters was organized, and today additional troops arrived in the namsky district group of 35 people, the mobile group of the main directorate of the ministry of emergency situations of russia for the republic of sokha yakutia, five units with

which, despite the winter landscape, came out en masse from berlock, now also typical of the typical phenomenon of northern nature, there they are rolling, playing, waking up. the clubfooted ones seem to have lost their innate fear of humans, every year they increasingly attract attention to themselves, some of them calmly swim in puddles not far from the lined roads, and these connecting rods completely imagine themselves as full-fledged

participants in the road traffic. i'm afraid answer. to suburban villages and residential areas of magad itself. for the last few years, bears have also been coming home, last summer a brown invasion more than once led to tragedy, three local residents died after an attack by predators, the regional ministry of natural resources recognized that measures to combat conflicts with wild animals are insufficient, in the vicinity of magadan and other populated areas for the first time , a kind of sanitary zones were created. for us, the main task is to prevent, of course, the presence of a wild animal within the radius. behind experts monitor the movement of animals in the surrounding forests using drones. they did not save much on models and components; in order to detect a walking threat even in the dark, the drones were additionally equipped with thermal imagers. from a height of 100 m, the main thing is that we can be seen, but if the bear is bigger, it will definitely be visible. the procedure is as follows: if the operator manages

to detect a bear or a whole brown family in the hills using a drone, he promptly transmits the information to the hunting control department. human peace. large beggars who accustomed to receiving food from human hands, often in someone else who provokes bears to violate, they go out onto the country road and test magadan drivers for stress. our people are kind, they try to feed them, which is absolutely forbidden to do, in fact it is a very dangerous predator, scientists do not discount another reason for the massive invasion of bears into populated areas, the population has recently grown significantly, according to census data, the number of clubfooted bears in kolyma has exceeded 17 individuals. this year

officials have opened the official hunting season earlier than ever, but this measure may also be ineffective. in joints without harm to the stomach. rivmoflex helps reduce joint pain without damaging the stomach, and also normalizes the level of uric acid and prevents its deposition in the joints. revmoflex evalar -

movement without pain. if your joints bother you when the weather changes, take rheumoflex. it helps reduce joint pain without damaging the stomach, and also normalizes uric acid levels. revmaflex evalar - movement without pain in any weather. so, there is a changing of the guard on european territory. one anticyclone has gone south, and is being replaced by the next one: from scandinavia. a cold atmospheric front will slide between them. today it crosses the northwest, and tomorrow it will descend to the south of the central region, dotula and kaluga. there may be short showers, even thunderstorms. in the volga region in the chernozem region there are no drops of rain yet, and from bryansk to saratov - 24:26. in the south, the weather is recovering from prolonged bad weather, in krasnodar and rostov-nadon, sunny up to 28 on the sea coast , more modest 22-23 in the baltic resorts in kaliningrad, also 23 with light rain, in the north with wet snow, in burmansk and

naryanmar just above zero. in st. petersburg tomorrow there will be bright sun and +18, in moscow it will be 23:25 and short rains, a thunderstorm is possible, and then calm warm weather again. thank you, that's all, see you later. only in alfabank, spin the reel in the application and receive a supercake up to 100% every month, and up to 30% in categories guaranteed. if you don't have a card, order a free debit card alpha map. not just profitable, alpha profitable! choose your favorite brands at wildbries, discover the world of sports with our collection of products for an active

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you should have gone for a diagnostic, but semyonovich said: don’t get under the hood, woman, men, don’t slow down, get a medical examination, health is important here now, beyond, her weight is 190 kg, but she considers her main problem... her legs, which are constantly increasing in volume, in our studio lyubov sardino, lyubov, hello, hello, how old are you, i’m 42 years old, what’s your height, 175 cm, you know your measurements, yes, bust size 150, waist size 150,

hip size 160 cm. i wear size seventy-four, it’s practically not on sale , sewing to order is beyond my means. olga, what is the normal weight for such a height? in this situation, of course, the weight norm is very much exceeded, more than three times, this is already hyperobesity and is considered the third stage, it is very dangerous because it can lead to death by... in principle quite serious emergency problems of some kind, a stroke, a heart attack can happen, this is the last stage of obesity, yes, this is the last stage of obesity, love, how long ago did you start gaining weight, i started gaining weight in 2020, then my disease was just beginning, they started in 2022, my legs hurt very badly, they grew terribly in size, i became dependent on

people close to me, that is, i could not move without outside help, but at 42 years old, you know, for a woman life is just beginning a second wind opens up, for me, for me, the opposite happened, i became a second group disabled person, i am a hostage to my own legs. and i can’t go out for a walk in winter simply because there are no shoes that i could wear. we see that you have terrible ulcers on your left leg. how long ago did they appear? these ulcers appeared this year in april, it ’s called phlegmon, this is the second time a relapse has happened, my first relapse happened in

the twenty-third year, i... a trophic ulcer formed on the right ecrocnemius muscle, now, thank god, it has decreased slightly in size, this year there was a terrible relapse again, it was terribly painful, it was accompanied by a temperature of 40°, my relatives were very scared, and my little sister contacted your program, novel, and what are the dangers so? ulcers why do they even occur? well, firstly, edema itself occurs for several reasons, they can be divided into general causes and local, general causes - this is fluid retention due to some kind of circulatory disorder, which in people with excess body weight is often heart failure, and local causes are a violation of the outflow of intercellular or lymph fluid or venous fluid due to

blockage or some other reason. obstructions in the vessels in the lymphatic vessels, venous vessels, but as a result of these edemas , the nutrition of the tissues is disrupted and ulcers, trophic ulcers develop, then an infection occurs, this is dangerous because gangrene of the limb may develop, which will require amputation, or generalization of the infection may develop up to sepsis and lethal outcome if treatment is not started on time. tatyana, i see you feel bad from what you saw, i’m just in shock, and... i don’t understand, this is due to the fact that you eat a lot, that is , it is due to overeating, of course, first of all, this is due to excess intake calories and nutrients. maxim, why are the ulcers such a gray-black color, what does this mean? necrosis and tissue rejection occur there, the higher the body mass index, the greater the weight, the greater the likelihood of such skin problems and

probability of occurrence. yasv is also love, do both legs hurt equally or does one hurt more, the other less? when a relapse occurs, both legs hurt equally, at the moment, of course. that is, so that the legs do not leak, so that it is dry, so that the infection does not spread further, but does it help for some period? yes, in november 2023 i was discharged from the hospital, in march the problem

returned, can you no longer walk without a cane? no, do you also use a cane to get around at home? yes, if not leaning on the walls, for example, at home i used to live in the far room, i had a bedroom. the farthest one, now i have moved to my son’s room, which is closer to the bathroom, because it is very difficult for me to walk far, when you sit, the pain subsides, no, when i sit, even bursting pains come from inside, it’s somehow terrible when you lie , you also feel discomfort when i lie on my stomach and lean on my legs or elbows, so that there is less pressure in my legs. pressure, then it’s easier, but you can only lie on your stomach, well, on your stomach, on your side, yes, laris, imagine some kind of torture, constantly to feel such pain, you know, what i see, i see a young woman who is suffering, i have only one thought: well

, out of nowhere, everything was fine, fine, then she woke up in the morning and this terrible tragedy began, i have a hard time imagining it, well, that is, it seems to you that she is directly saying that love has neglected itself, well, we need to figure it out, because medicine has been observing her for 4 years, trying to help her, but apparently there is no qualified medical care that would solve the problem of love, i agree with larisa, who said, on nothing arises out of nowhere, lyuba, you said 4 years ago, yes, you woke up, you had some kind of stress, a nervous shock, what did you have, tell me, here... 4 years ago i suffered from bronchotrachitis, the illness was very long, and at first i was treated for 3 weeks, then there was a week break, i went back to work, then everything worsened again, i was treated again for 2 months. lyuba,

please tell me, before this stress , what was your weight, about 90 kg, and suddenly this glutton has gone, i eat the same thing, as before, but only the weight began to increase, well... did the amount of food increase or the frequency of intake? no, everything is the same, love may think that its diet has not changed, in fact, maybe somewhere there is still an excess in nutrition, and if we return again to the disease, and since love says yes, that you were sick for a long time, were sick for 3 weeks, went back to work for a short period, fell ill again for a long time, the weakening of the body causes all systems to fail, and if, for example, after a long illness we do not if we restore our intestinal microflora, then digestion will be very disturbed, and people complain that after a long period of illness, they suddenly begin to gain weight. roman, what kind of disease was this? trachiobronchitis

is an inflammation first of the upper respiratory tract, which goes down and then inflammation of the lower respiratory tract develops. usually antibiotics are used in the treatment of such a disease, antibiotics disrupt the intestinal microflora, this can... lead to some kind of dysbiosis, syndrome excessive bacterial growth, the second group of drugs that are used in the treatment of long-term trachyobronchitis are hormonal glucorticoids, these drugs also contribute to weight gain and changes in metabolism. lyubov, you said that you were working then, yes, then i was working, are you working now? at the moment, no, i have a second group disability, a large disability pension, 19600. before the health problems started, where did you work? i was working. at a livestock complex, a pig farm, what are you doing there? were engaged in, was it active work? yes, it was a very active job and i loved my job very much, i worked as an assistant foreman, i worked as an accountant, and what

were your responsibilities? assistance with the corral and grazing of adult sows, with the delivery and acceptance of piglets, and the accounting of piglets, the ferring of piglets, and there is work with the team. you say with pain, it can be heard that you want everything to be as before, but are you doing something for this, for example, are you currently on a diet? now i have completely given up... but i haven’t given up dumplings, what does your daily diet consist of? well, in the morning i get up, i drink either a cup of coffee, albeit with sugar, yes, or a cup of tea, without sugar, tea, then at lunch i eat a portion of either the first or the second, one of the two, when i was still working , in the evening i could afford a cutlet there, the second one, because during... the working day i was not able to fully, let’s say, eat,

now in the evening we try to eat simpler, make a salad there or something so that it is not heavy, anastasia, what can you say about nutrition of love, he eats irrationally, especially the previous story was, but here he was 90 kg, it was already obesity, it was beginning, it was the first degree, and - what does he say? the heroine had long breaks between meals, the body, when it overcomes hunger, when it endures it, it turns on the mode of such self-preservation, accumulation, yes, when we do not eat irrationally enough, it really happens that at first glance the patient, he somehow maybe he doesn’t directly eat a huge amount, but there is a carbohydrate-based diet when... lacks other important food components,

such as fiber, these are vegetables, fruits, this is protein, these are good, healthy, complex carbohydrates, for example, these are whole grain cereals, what remains is, let’s say, well, my patients say: i grabbed a bun, therefore, it is fast, it is fast, fast energy, in the end we intercept fast carbohydrates, sweet, starchy, because it gives fast energy, and we don’t notice it, and the metabolic processes change , they slow down, hormonal, secondary disorders appear, it is disrupted in general exchange substances, it slows down, the body goes into some kind of hibernation, now the important point is to establish regular nutrition, good nutrition, but not go into the phase of eating disorders, when a person, without realizing it, enters into a situation of loss of control over food, in ... i would start to eat , i would start to eat adequately, but i start to grab

everything in a row, and this is also preceded by various diets, by the way, and situations when hunger was overcome, and food was eaten in the evening, especially such an uncontrolled one, love, what's in yours what is the worst situation for you, what are you most afraid of? well, most of all i’m afraid of being left without legs and completely dependent. from loved ones, you are afraid that they may simply be amputated for you, maxim, by what indications is it generally determined whether amputation is required or not, when firstly, we tried conservative treatment with compression therapy, medications, and minor operations to remove excess skin, yes, if we applied all this and did not have an effect, and the disease progresses, especially if it also becomes infected, and even this the infection gets into the blood and goes further, then in

this case, unfortunately, it may end, that is, there may be a situation when the doctor has no choice but to prescribe amputation, yes, absolutely right, love, who is helping you cope with difficulties? father, his wife, my sister, my friend, and of course, my only son, you didn’t name your mother, she’s missing. my mother died a long time ago, it was in 2006, and you didn’t name your husband either, are you not married? my husband also died, just recently, what happened to him? he had occupational lung disease, he worked in the oil industry, 28 years, unfortunately, he passed away in december 2023, please accept our condolences, how are you coping with the loss, it’s very difficult for me. besides.