tv Kto khochet stat millionerom 1TV October 21, 2023 8:05pm-9:00pm MSK
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judging by the pace of development of china, the great wall of china was built over 500 years not by the chinese, but by their neighbors. labor lessons, did you know that labor lessons were invented so that children, looking at a trudovik, would see what would happen to them if they did not study well. after the orange revolution , the russian cartoon the little mermaid was banned on television in ukraine, since the name contains the sacred word sa. adjacent to the word russia, what is an american crossword? this is when one line needs to be filled in with x's and the other with o's, but did you know that american police officers go in pairs, because one of them can write, and the other can read, sometimes a third joins, who like to chat with educated people, but in general, you know what will happen, whether on television, i am the first, i often joked about our ruler. and i’ll tell you, i
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’ve been liking our president lately, why? yes, because he develops some kind of sense of pride in young people, well , he says: we’ll take estonia for ourselves now, oh, we’re scared. estonians, by the way, have stopped eating turtles and snails; it’s not good, it’s blasphemy to eat your own kind. in general, i think that everything needs to be approached with humor . treat, don’t worry, especially, but i like it when especially putin is among this big eight, he answers so quickly, the journalist has not yet had time to ask the question, he has already answered, and he has already answered in such a way that the journalist does not want to ask a second question, between other things, and at this time they are still whispering an answer to bush, he has already been put in an awkward position to ours in advance with his answer, and how did he do this, he is the prime minister italian, well, i really am!
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our president, when the new prime minister, who was elected in italy, decided to make a reprimand to ours in st. petersburg, and said that something is not right with the mafia, we screw him, the mafia says the italian word, not ours, he remained silent, everything else, the rest of the remaining summit, the summit in russian is similar, now i like it too, we bulgaria is joining nato, for god’s sake, guys, and we are conducting exercises with china. you can take estonia for yourself, we have india on the way, take bulgaria too, estonia, lithuania, you will all be chinese anyway, but we won’t, but because our winter is such that not a single chinese will survive, they will bypass us on the direct road to you, we will conduct a training together and go there towards you, that’s right, to the east foreign policy, this is very wise, in general, of course they laugh at me
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, they say, they say, zadornov is paranoid, he talks about america all the time, but in reality it ’s not me who is paranoid, it’s television that shows the same concert all the time, actually i have and others there are numbers and stories, but it happened, it happened completely, it happened something paradoxical, people meet me on the streets and say, we were in america , you can’t imagine, they are so stupid, i’m proud, 70 years old, the communists couldn’t explain why they think americans are bad, but they showed me only one concert, the whole the country began to play this game, they even stopped telling jokes about the chukchi, well, what is actually interesting about the chukchi, there is one interesting chukchi, and that one is abramovich, i can now make a new program based on the stories of people who send me letters, emails come, stopped on the streets, two
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young men were spotted on the street, although this happened in latvia, and they said: “we were on an internship in america, an incident that will make you proud now.” and they tell me that they started boiling potatoes, there was one, one of them had a birthday, they invited the americans, the americans asked, why are you boiling potatoes? and then one of our people says, well, it’s cheaper than buying it in a store , and the american asked a brilliant question, how do you know that it’s cooked? i understand, you are already overcome by pride in us, i always said that we have a special understanding , when there, say, i opened, opened the gate to the old believer in the far east, and the gate was difficult to open, and i asked, kupryanovich, why is it so difficult for you to open gate, and he says: but you opened the gate, i have a bucket of water filled, i always say, from the point of view of thinking, we don’t need nuclear
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weapons, we can cope with our imagination, you know, when snow falls in america, they are in a coma the economy is falling, come to my concert no one came to new york because the snow fell... half a centimeter thick, you couldn’t see the dividing strips, how stupid they are, and our air condition is -25, i see three people running after the bus, three, one old guy got there , experienced, with the clang of a knight of the tefton order, he jumped onto the bus , everyone is looking at him where the lass comes from under his feet, ready, dial him. he has graters tied to his feet, now compare their thinking with our thinking. so, our guys taught them how to check potatoes to see if they are cooked, that is, pierce it with a fork. sometimes i
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return to what i was distracted from. the american checked, brought potatoes, why am i smiling, i can imagine what will happen to you now. ready? and then ours began to boil eggs. the american says: i went to check with a fork. russian people have crazy energy, but the program has gone astray, only russian minibus drivers play races with each other when they have a full cabin of passengers. and as they overtake, they stick their tongues out at each other. and only russian passengers. everyone cheers for their driver, and when he overtakes, sticks out their tongues at that salon, no, well, in general, i always say, these people will not live well until logic is restored, when a man
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came to the market with me, spoke on his cell phone and said to his wife: wife, maybe these tomatoes take, in conclusion, in conclusion... our energy, i saw our businessman, an oil worker in tyumen , who was a terrible picture, you can’t imagine at night, he was running for an umbrella in a thunderstorm, shouting to umbrella, stop, you bastard, otherwise i’ll drink, sorry, all. academician vladimir skulachev was called lord of immortality. he was sure that
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he had invented a substance that could slow down the aging of the body, but quite recently, his life was cut short by a tragic accident. this is the first channel, good evening, i’m dmitry borisov, our exclusive, today’s leader. the secret of the scientific invention of a world-famous biochemist, a person has a program in the brain, there is a clock there that ticks, at the hand hour, the clock gives a signal to grow old, the aging hormone appears, or the youth hormone disappears, we cannot choose between these options, bye, and this signal goes into the tissue, all his life academician vladimir skulachev studied the hormones of aging and the hormones of youth, he tried to understand how to slow down the ticking clock in our brain, which measures how long we have left to live, he studied not only the physical capabilities of our body, but thought about mental causes of aging, believed that a person gives himself an attitude toward aging and death; a person, as a rule, dies with the help of his own decision to die. vladimir
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skulachov was born in 1935 in moscow, at the age of twenty-two, graduated faculty of biology and soil science at moscow state university remained to work there. most of his scientific works, works and research would be aimed at defeating the aging of the human body, he persistently searched for a recipe for longevity , argued fiercely with colleagues, and if there is a gradient, what if there is a gradient, what kind of gradient, well, a gradient, let’s say in energy, why a gradient , why, no, no, no, the culmination of his scientific research was the invention of the elixir of longevity, this is the most powerful antioxidant of plants, in general , plants have a much more powerful antioxidant, than in animals. a couple of years ago, elikir skulacheva was approved for sale in pharmacies in the form of eye drops that improve vision, but vladimir petrovich took the elixir orally, i have been taking this substance for almost 2, almost 3 years, this substance is corrosive, and nothing bad happened to me, i am with it
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argued strongly about this, because eye drops are not for you, this is very serious, because they have not been fully tested, to which he said that this is nonsense, he is already 80 years old, so he will not wait for our stupid pharmacists. research will be applied now look at these shots, at over 80 , vladimir skulachov looked 20 years younger, but he felt and worked like a forty-year-old. i was caught up in the fact that, uh, that uh, i worked for 14 hours, went down twice to make coffee, so i worked at about 40 years old, nothing foreshadowed vladimir petrovich’s passing away, he was full of energy and plans for the future, almost every day he came to the belozersky institute of physico-chemical biology at moscow state university, which he heads, can sudden death, death... even be accidental, this is a tragedy, but
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he, it was just an accident that led to his death, if he could choose, maybe he would probably choose something like that. vladimir petrovich was very fond of quoting wolend, saying that not only is man mortal, he is now suddenly mortal. the sons of vladimir skulachev followed in his footsteps. two of them became biologists and two more also came to help their father from other areas. when he invented his unique substance, now they are all not only keepers of his secret knowledge, but also successors of his lifelong experiment. death was invented by evolution for its own acceleration, that death is not necessary for living beings. today, the children and colleagues of vladimir skulachev will talk about his life’s work, about the elixir of longevity. in the studios today there are two sons, the grandson of vladimir skulachev, fedora severin. vladimir petrovich's pasanok, whom he raised from the age of 5, vladimir petrovich became for him not only a second
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father, but also infected fedor with a passion for biology, today fedor fedorovich, doctor of biological sciences, head of the laboratory within their scientific-family project. boris kulachev, vladimir petrovich, is 22 years old, and graduated from the faculty of biology of moscow state university, and is now a master’s student. well, yanaki kulachov, and boris’s dad, in fact, is the youngest son of vladimir petrovich, yes. the youngest of all, chose a different pursuit, yes, yes, he went in, but when his father said he had to, he came to his aid, absolutely right, it started in 2005, and vladimir petrovich gathered us all, he had, this is his scientific idea, but he came up with the idea that it is possible to stop aging at that time, the substance, well, i came up with it in my head, yes, i drew it , as he said on a napkin, we had a kind of dilemma, leave this project within the framework of science, it was going to end, let’s say there were publications of articles in some good scientific journals, yes,
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but this was not enough, in fact, lav petrovich, he wanted to make a medicine, and this is a completely different story, this has to do with science, but it also has more to do with pharmacology, and also science, and also science, of course, i have that the science of biology, the science of biology, here is vladimir petrovich decided that no, we had to make a medicine, that we would work on creating a medicine, based on its fundamental developments, so we needed to synthesize this substance, we needed to make it a pharmaceutical substance, that is, according to certain regulations of the ministry of health, this a huge amount of work, very lengthy, very expensive, within the framework of, let’s say, an ordinary scientific grant, it was simply impossible, that’s why vladi petrovich said that no, we are starting just such a business project aimed at combating seniority diseases, with aging in general and the creation simply within the framework of this project, your dad was afraid of getting old, it seems to me that my father was not afraid of anything, that he had
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a great idea, he was passionate about it, that’s all, that is, that is it seems to me that he didn’t have time for fear, he didn’t grow old in the end, in fact, because unfortunately, leaving life was associated with an accident, and he didn’t have time to build, he was active until the very end. the very end, well , your brother maxim has a different opinion, that there was only one fear, let’s see. vladimir petrovich really didn’t want to become old, his main fear in life was that one day he would have to retire and read klyuchevsky, or something else from history, that he would no longer be able to lead a team, would not be able to write articles, will not be able to drive his sons so that they finally do something sensible, so he will sit on the sidelines and watch it all, it was the most horror and nightmare, he always struggled with it, moreover, all our developments are aimed at the fact that the person didn't get into
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this is a humiliating, unworthy state of a person, when he simply cannot work anymore, and in this sense, in some way, this is a tragedy, and he, this is just an accident that led to his death, in general, if he could choose, maybe he probably chose something like this, he will continue to work for several more years after his death, because these are... ideas and they exist, they are fixed, all this can be done, in in this sense, it didn’t happen at all unexpectedly, well, like any accident, it’s impossible, somehow predict, he vladimir petrovich was very fond of quoting woland that not only is man mortal, he is now suddenly mortal , this is exactly what happened, and what happened was an absolutely banal story, he was walking up the stairs, stumbled and fell , actually
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hit his head, unfortunately, he died 2 days later, so in the end he didn’t age, so in the end he didn’t age, in fact, because he, he led the seminars to the end. he was engaged in science, wrote articles, in fact, one of his most, let’s say, serious articles it came out, it came out after death, you agree with your father, he had a theory that a person dies when either no one needs him, or he no longer needs anything, i agree, well, that’s how you just look at these frames, here he’s already over 80 and somehow, well, 70-80, but he looks, well, that’s what everyone would want, of course, at this time. yes, he looked very, very good, until the end he didn’t have any wrinkles even on his face, towards the end of his life he began to not sit down, turning black again, so we also noticed this was also surprising, we have footage of how vladimir skulachov actually looked, well here right in the last months of life, 2022.
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hello, today is february 21, twenty- two, this is a wonderful holiday for everyone who is involved in aging. i congratulate you on the holiday of february 21, well, it’s a holiday, i’m just a pitiful 87 years old, i went to a seminar, that is, work is in full swing, absolutely, yes, teaching, scientific, yes, he also has a department under his command, he founded faculty at moscow state university, by the way, is now the highest-rated faculty, by the way, it has its own, physics-chemical biology, and well the third, of course, is that our project was headed, this very project is the practical application of yonovachev, we did not come up with this ourselves, the fact is that the class of substances that petrovich invented, then, in my opinion, the dutch named them in his honor,
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yonos kolachev, the whole project, in fact, it is dedicated to the fight against aging, and we are just studying one of the substances that belongs to the class of yalachev substances, this is our sk-1, that is, there are many different substances , the whole class, well, tell us, the whole class, that is, they do this, they for different purposes, how do they work together or, there are substances for medical purposes , there are for research, there are for cosmetics, for cosmetics, yes, they all work, well, those that work, those that work, those that are used. a tricky answer, but an honest one, of course, there are a lot of them synthesized, here are some successful ones, should you use them on yourself? no, somehow i can’t decide yet, but it’s you personally, no, because i know that many people are trying it, yes, yes, i use eye drops, every day, the ointment also works well, i got scratched or burned all over there, that’s it i tried,
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zhelanić himself used it before pharmaceutical approval, that is, everything on himself, he actually drank, a certain solution, well, we call it a pill for old age, not in the form of a tablet, in the form of some kind of elixir, let’s say, a solution, here and he didn’t want to wait for all the permissions that are required, but according to the laws, as the author, he could use it, and he actually conducted an experiment on himself, drank this substance every day, 4 ml, and what is the mechanism of action, well, just sounds like a fairy tale, everyone wants it, but there’s 4 ml a day and there, no, well of course, it doesn’t really look like skiing at 90, but you see , the experiment is fundamentally incorrect, because to do a correct experiment, you need to have not just one academician, but about a thousand, because maybe you’re just lucky so, maybe it’s genetics, well, that’s why the family is big, just in case, so that it could
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be carried out, maybe trained on children, then in principle there are no problems, on grandchildren, and grandchildren too. we still need many, many years to fully understand what petrovich came up with, we have good results there animals, yes, but we need to reach people, while we have results in people, these are our eye drops, this is the same substance that petrovich took, only it is in the form of cool drops, here it is... everything is officially approved, i even bought my own eye drops at the pharmacy, it was interesting to come to the pharmacy to buy, it’s actually such a strange feeling, you come to the pharmacy, by the way, there’s a box, this box, we came up with the design, we came up with the substance, well, we came up with everything, here we are you made it yourself, about two at a time, you think why it’s being sold, and you’re buying
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it, it feels like at first they didn’t believe that you were actually a developer, yes, you said that we’re developing this, yeah, yeah , of course, they said, get out of here, yes, yes, yes, in general, the idea of this project, it was conceived in 2005, of the country, he was still a patriot of moscow state university, he wanted some kind of thing to be born at moscow state university, now it’s fashionable to say, there is technological sovereignty, there is all this, even then he wanted to make a breakthrough technology that would change the world, that is, he actually compared our project, well, like something like gagarin’s flight, let’s say, yes, because if we succeed in the end, then we are what we intended, we will actually open a new one about medicine, and what is the goal, boris, what, well, he started from his theory of aging, in fact, if - in simple words, then the idea is that while we breathe,
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we burn ourselves out very slowly, and thus we age, this happens due to free radicals - oxygen , they are located in mitochondria, these are such small organelles that are in each of our cage, that's the idea that before de. no one thought of creating a substance that would penetrate directly into these mitochondria, namely a medical substance that penetrates targeted - through the second membrane of the mitochondrion and it binds to these radicals and thus we slow down our slow burning, let's say, we slow down in this way, and in this way in any way, it’s possible to stop it altogether, stop it completely, theoretically, theoretically, most likely not, because, well, it also seems to me that this is an excellent first step, we said it, but we still need to move further in the same direction, this
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is not a magic pill yet, you need to go there, but you calculated how long a person can theoretically live, if everything works as planned, there are no accidents there , well, and other circumstances, that’s how complex the human body is, if you connect the right radicals, the right substances like this, it’s very difficult to say in the mice that we have, but they are encouraging, and you can extrapolate to humans, but the mouse lived there about 20 % longer than the mouse that did not consume the substance , the most important thing is that it is not the longevity that increases, but youth itself, that is, this is rather aimed at this, that is, they ended up dying young , young, well, by the way, this is also important, because of course, of course, what maxim said was that we need to get rid of this humiliating old age. here and to the very end on alpine skis, this is the goal, this is life, well, yes, if it increases by 20%, well, by the way, 20% -
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this is actually, well, in the case of a mouse, it lives there for 3 years, 20% is not much there, but in the case of a person who lives 8, 20% is quite good, well , if it’s from 80, then yes, it’s immediately 96, if from 100, and we kind of figure 100, we kind of want 120 years, then 120, yes, yes, who else did you conduct experiments on, which ones? creatures, well, there are a lot of them, these are worms, yeast, yes yeast, infusoria, ciliates, fish, then more, all the fish too, they all lived longer, i didn’t ask about the trembling, that ’s right, by the way, it didn’t start to germinate, for some reason they are too far from a person, there they have a different type of metabolism, then there were plants, so there were mushrooms, they grew a mushroom, which, in general, in the end we did. they didn’t wait until he did, when he died, it turned out best with mushrooms , that’s who is better, on insect mammals in general, where and how it works, insects
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, it turned out well, yes, that’s it, actually, muhidrazophiles, and muhidrazophiles , it’s not clear, really, why extend their life indefinitely, but we studied the mechanism why this happened, of course, yes, what exactly is improving for them, maybe it will work out somehow apply it, but somehow they got eternal ones - they didn’t get it, i don’t remember the magnitude of the effect, but so, good, good for them, this is an idea by the way, that it’s not just life that is extended, but youth that is extended, this is very cool, because this is the main thing, i hear all the time in the gym there from opponents of fitness and everything else, like why now spend so much time on the fact that you will live longer there at 80 or at 90, and now you are wasting your time this means that this is the current situation, when you are 20, 30, 40 there, in general, fitness... fitness is walking correctly, correctly, absolutely correctly, and this prolongs youth, including, yeah, let's watch another unique
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video of family advice. i have news, i was just at the institute of eye diseases in rusalima, there i met with valery petrovich erichev, he has been observing for more than 40 years a woman with glaucoma, which means that one of her voices has been lost, yeah, the second one is breathing, as they say , and it has already happened there. to narrow the field of view, the fact is that now there is definitely a noticeable expansion of the field of vision, when he said something, i asked, but in general, this is how you feel, that this is the only patient like this, the patient, yes it worked, no, he says, there are a number of other cases , parasitic and unprecedented, when cataract disappears, we have more and more data about
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what alzheimer’s disease is treated with, this is the article. in kolusovaya in the journal of alzheimer's disease, in ratsoxis this substance, betaam, a substance of alzheimer's disease , grows with age and this is prevented by iska, some isoxys and wister were lucky, they were fed iskaka from young nails, but they don’t have nails, but like those, that’s how it declined, well, that is, in principle, the floor is not plowed, you can cope with various ailments theoretically, but absolutely true, so yes, eye diseases respond very well, now it’s like this... here’s the section on bad advice, right away with a note not to do this, but here’s the eye shape, it’s somehow different from all the others, there from what’s inside, there for example, vladimir no, well, that is, it just depends on how it depends tube, no, no, no, there is not only a tube, of course, there are also a few other auxiliary substances, all like that, yes, but these, but these substances are like, that is, they are standard, but they work everywhere, yes,
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all the substance is here the same thing, that’s the same thing, i’m galloping alone, just another different concentration, it’s not the same, don’t take eye drops, but yes, no, pointless, pointless, it might not hurt, but they didn’t separate me, what’s not necessary, no, no , just lose money, no, there is, there is a benzoalkonka preservative, which, well, buy it, yes, inside, there will be debutoriasis, but maxim said that he was against what dad used internally, here it is. petrovich also took a systemic drug and - i strongly argued with him about this, because these are not eye drops for you, this is very serious, because they have not been fully tested, i was not very happy, this is called bioavailability, you drink how much - then there is a milligram of the substance, how much enters the blood, this percentage, it is far from 100% in the dosage form that we used, we are now working on it
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improvement, it seemed to me that it was too early, to which he... said that this was nonsense, he should try already, he is already 80 years old, and in general he is already old, and it is not known how much is left, so he will not wait for our of this stupid pharmaceutical research, will apply now, as a result, for almost 88 years, he is absolutely active, runs the institute, heads the faculty, writes articles, sets tasks for us, i don’t know why this is, maybe it’s genetics, and maybe this. .. his commitment to work is known to be prolongs life, prolongs youth, as long as you have something to do, you live longer, or maybe this is in some way the effect of our substance, i would like to think so, but he has been taking it twice a day for 12 years now, i have been using our eye drops , i still read without glasses, and i’m happy with my eyes, well, besides, with these eyes i read the results of clinical studies, i see
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that this... the device really works, it protects the tissues of the eye, and speeds up recovery from all sorts of unpleasant consequences like working on a computer, well sounds like a fairy tale, sounds like a fairy tale, on the one hand, but on the other hand , there’s still a lot here, but if so, here’s what we still need to figure out with the same eye drops, we need to do clinical trials on other diseases, not those that are now included in the instructions, in a few minutes, what else did academician vladimir learn? about the mystery of life of death, who are naked mole rats, unique mammals that are said to never get sick, and the dangerous experiments of predecessors, soon let's come back, beautiful, charming, always young elena prokolova, larisa ivanovna, yes, i adore my numbers, 70 years old and a wonderful age, it makes you sum up some
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results, make plans. ex-husband, yes, beautiful, lena watch him, when she can’t get up , her leg is broken, she has a stroke, and the viewer is waiting, she gets up and walks, i still don’t have gray hair, i can lend it to you, no one has ever given me flowers , this is not a ring, some kind, this is a percy, this is a million, this is a peach, you know, we have it. larisa ivanovna, i want it, see after program time. montechoca cognac, a product
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of the stellar group. i decree, award the title of hero of ukraine with the honors of the order of the power of stepanov. stepan's father. was a ukrainian greek catholic priest, and he, of course, was integrated into the church structure, which was permeated with hostility to russia, he was quite flawed, sickly, short, his hands somehow dragged behind him, and such people, as a rule, they certainly experience inferiority complex, the guys from bandera’s security said with indignation, beat his wife, or even kicked her in the stomach when she was pregnant, when a child grows up in an atmosphere of... violence, this becomes a kind of permission to use violence. as a child in his youth, he had the nickname koshkodav. avver actually took ukrainian nationalists under his wing, and this came directly from bandirakh. on
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august 29 and 30, 1943, i massacred and shot over 15,000 civilians. the german troops were shocked by the cruelty they saw from banderas. bandera's diagnosis premiere, tomorrow on the first. once again everyone , good evening, we are back on the air, how to prolong life and stop aging, vladimir skulachov tested his discovery, which he called immortality, but died by a tragic accident. our exclusive today is his children and grandchildren, who continue to test themselves. there is such a point of view that vladimir petrovich. the last 20 years of his life , he focused on aging, because he was afraid of growing old, and he did this mainly for himself, for some reason they were embarrassed to do this, it is quite dangerous for scientists, the best minds of soviet science were also obsessed
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with searching for a formula for longevity. in the mid-twenties of the last century, the founders, the first director of the institute of blood transfusion, alexander bogdanov, were engaged in experiments on rejuvenation by transfusion of blood from one person to another, they say that in this way bogdanov knows of a case when a blood transfusion was given to lenin’s sister, maria ulyanovova, she suffered from a serious illness, connected with blood, and it is believed that this transfusion greatly extended her life. his experiments were encouraged by stalin, who ordered the creation of a special institute for the scientist’s developments, but as it turned out later, this path turned out to be wrong, and bogdanov himself was a victim. own experiments, died from general intoxication of the body after 12 procedures of blood transfusion of a twenty- one-year-old student who was sick with tuberculosis. and another unpleasant thing became clear: if you add rh positive blood to the blood of a rh negative person,
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then the body will begin to produce such antibodies, if the transfusion is continued and continue, then these antibodies will become more and more, more and more, and eventually the destruction of the blood will occur. in the fifties there were very popular ... physiologist academician pyotr anokhin, he preached the original theory of sleep and wakefulness, hunger saturation. according to his teachings, it is necessary to sleep, be awake and eat at certain times. he was a supporter of therapeutic fasting, but did not live to see 80, dying at 76. another academician-surgeon nikolai emosov, already at an advanced age after a serious heart operation, also decided to defy old age, ron came up with the system, a load-limiting regime, which included three main points: abstinence, the idea of maintaining weight according to the formula growth -100, physical education , mental management, and although he lived to be almost 90 years old, at the end of his life the academician admitted that old age still won him, he died of a heart attack. well, let’s return to vladimir
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petrovich and kulachev, we were joined by his long-term associates in the scientific search for how to defeat old age and prolong life, boris finyuk, biochemist, doctor of science, deputy director of the research institute of physical and chemical biology named after belozersky msu, 12 years yes, i worked under the leadership of vladimir petrovich. i was still in graduate school under his leadership for 12 years. konstantin lemzaev, biochemist, candidate of sciences, leading... researcher at the same institute, i entered graduate school in 2002 and my supervisor was petrovich kulachev, but you were his right hand in all matters and administrative and you know how as it was, he really was obsessed with prolonging his youth, not right away, that is, when we met, in fact, for the first time in 2002, he was certainly already very passionate about this particular science , but i wouldn’t call him obsessed yet, but because further delving into this science, he seemed to gradually... understand what he could do in this area, then,
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probably, it can already be said that his obsession was growing, who were these diggers , why did he need them? when he first learned that there were such animals , extremely unusual, interesting, this is them now, yes this is yes, yes, yes, this is them, and this here is a photograph, when he first saw and held in his hands this unusual animal, such a rather specific species, let’s say, an animal for amateurs, this animal, when he looked into its eyes, he immediately realized that this same animal must be in moscow, and these photographs were taken in the fourteenth year and 2 years later in the next office of vladimir petrovich they equipped a special room, where, in fact , a whole colony of those naked diggers settled, simply because he really thought that i knew that the future lies with these animals, with the revelation of the secrets of their longevity, perhaps the secrets of our longevity lie, so they really don’t get sick with anything, but no, but they don’t... as if they get sick much less than other
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animals, no less than expected , let’s say, from such animals, at one time it was believed that they had no examples of cancer, but then it turned out that there are some, but the truth is again with a blot, that they do not die from them, that is, these are unique animals according to different parameters, and how long they live in general, and i specifically looked, in 2022, and an article was written that one of them is more than 40 years old, please note that this animal is the size of a mouse, a mouse: lives 3 years, 2-3 years, and one of these animals already more. listen, do you know pritorovich wanted to extend a person’s life so many times, 20? as they said before, in fact, vladimir petrovich did not want to extend a person’s life too much, to prolong youth, well, yes, well, everyone agrees on youth, pay attention to what these animals look like, well to be honest, it’s not very nice, let’s be young, was young, but like this, yes, yes, yes, but like this, that is, everyone, everyone has a choice to look at this beast and say, you want to be... forever, eternal,
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but like this, partly yes, this is another discovery of vladimir petrovich, where he compares , let’s say, the signs that allowed this animal to live much longer with the signs of a person, in fact, if we compare us and chimpanzees, then we also live much longer than chimpanzees, these animals also live much longer longer than mice, and there are certain parallels, we visited the laboratory, looked at the barefooted excavators, and by the way, boris aleksandrovich showed us an experiment with them, let’s fast forward. and we’ll see everything with our own eyes, and here are two families of naked mole rats, these are african rodents that are social, they live in families, only one female reproduces, the queen, all the rest are, so to speak, service personnel, soldiers, foragers , nannies and so on, they live in underground labyrinths in africa that they dig,
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and this labyrinth here is simulated by plexiglass tubes, where we actually see these wonderful little ageless animals, it was by looking at them that he probably made one of his last great discoveries, namely, he proposed a theory of how animals can become ageless, this is the so-called theory of neutrality, in other words, speaking in ordinary language, vladimir petrovich noticed that naked mole rats do not look like adult rats, like newborn rats, they are bald, small blind, and even just look at photographs of naked diggers, adults and newborns, they are very similar, and then it occurred to them that maybe their very long life is connected with the fact that the naked digger was stuck in childhood, and then he suggested that perhaps something happened to people - something similar and by all accounts this is really true, because if you look at photographs of a baby
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chimpanzee of an adult chimpanzee, then the baby is anatomically very similar to a person, an adult champagne is completely different, this is the mechanism of prolonging childhood, it allowed both people and naked mole rats live so long, and everything you see here , these enclosures and laboratory animals, is all part of a large project to study the mechanisms of aging, the goal of which is to understand them, in order to then, by intervening, slow down human aging and ensure for people a much longer period: great longevity, a full life, and to save them from this humiliating non-adult senile state, which often occurs much earlier than we would like. listen, well, if naked diggers are stuck in childhood, the concept
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youth is also extensible, we want some kind of youth, eternal, there, well, at least probably twenty years old, well, between twenty and 40, probably, yes, in an ideal world, this is... a period, but otherwise i’m stuck in childhood at 3 years, and what to do about it? no, but here we are still not talking about three years, but about completely functional organisms, and here in the video where we saw, i briefly mentioned, one of probably the last greatest discoveries of vladimir petrovich, this is the theory of non-recurrence, vladimir petrovich was generally obsessed all the time with the concept that aging is a program, he always said, man and living beings grow old. differently than, for example, a car, a horse cart ages differently, and if in the case of a car or cart all sorts of damage simply accumulate over time of operation, something begins to creak, something cracks, then vladimir petrovich believed that living beings age according to some plan that is determined by their genes, and of course he was
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very interested in trying to understand what exactly was happening and how this genetic program specifically... and what he discovered really stunningly beautiful and convincing, he suggested that in the process of evolution , this juvenile period, not a three-year period, but, so to speak, a child-teenage period, it lengthens and organisms get the opportunity to reproduce during this period, so we see a photograph. an adult monkey and a cub, the cub is much more like a human, it turns out that the body continues to think that everything is still ahead and maintains the state of all its systems much better than when it decided that everything, as if i were adults, and then we move on by
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inertia and judging by everyone, this is really true, it was work in one of the most prestigious biological journals, and which is still probably one of the pearls of the publication, moscow university, that is, a long life awaits us after all in the young, reproductive age, which means that this is the idea of skulachor, yes, this is the idea of kulachev and naked diggers, in fact , this is one of the keys, which, if we can decipher, then we will be able to understand how exactly this elongation program is encoded in our genes youth, and having dealt with with this, perhaps we can somehow spur it on the person, so when will you give us the time when you will deal with your fellow countryman? and the work is going on, i hope that within the next 5 - 10 years, if not here then somewhere else, because we will be around, naked mole rats are being studied not only in russia, this is such a very popular topic now, in many laboratories there are colonies, and people are very actively studying these animals, there is another guest in our studio, an expert who
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is professionally involved in investigations and studying the facts, both from precedents known to all, and from some secret experiments, aleksandnov, good evening. good evening. diggers - this is now. what happened before? well, in fact, the history of life extension, actually the science of gerontology, its manifestations, i would say from childhood, probably go back more than one century. you can just mention alexander kaliostrov, city of saint-germain. many others, in fact, a very well-known figure like agasfer, will seem literary to many, but someone may not knows that in the 16th century, a man who presented himself as... a sphere allegedly cursed by christ, the british subjected him to very serious research, philological, humanitarian, at the level of that science, and he showed knowledge of both ancient languages and the geography of the ancient world, in general he was surprised, i would say those, his contemporaries in the 16th century, in general, this is, as they say, the history of science, but if we go back
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to our centuries, then of course the figure of alexander bogdanov in itself, here, it is in front of us, and he is like once was one of the pioneers of the theory that over pouring the blood of his younger self, he really was a unique person, in many respects, although he was probably mistaken in some way, but he further gave respect to our hematology, including gerontology, and alexander bogomolets, was his successor at the institute of blood transfusion , in 208 he took over the legacy, but speaking about bogdanov, firstly , he was a romantic from medicine, so it can also be expressed from big science, in fact, he really did experiment on himself, everything is said correctly here, he most likely died from hemolysis, and this is the dissolution of red blood cells due to an incorrectly chosen factor. but then they didn’t know yet, they just didn’t know, they just didn’t know anything about the resisfact, by the way, bogomolets later studied the fact of the first blood type, his successor, and
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he forbade even stopping the experiment when he was transfused with 900 mils of blood, death occurred , so by the way, the student with whom he had an exchange transfusion recovered from this reason to say that he was a god damn charlatan, no one can, he was an experimenter, he was a scientist, it’s just that everything was not yet open, well, science is developing errors empirical medicine for the incorporation of the empiric now is also again startups appearing here and there, what does it mean to transfuse blood to a younger person, the most famous biohacker, i forgot the name, who transfuses blood into his son, yes, there are followers of bogdanov, in the west there is a company that offers transfusions in the states blood from young people, it costs from 6 to 8,000 dollars, it is believed that it stimulates internal organs, in fact, absolutely, well, i would say it’s a hoax, because before this there were experiments on rats,
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in fact, it all started with rats, from the exchange blood flow, that is, when two rats were connected into one single whole, the effect of some kind of rejuvenation of the fixed organ was actually observed to prolong life, but until the moment when the blood flow remained connected, when they tried to do exchange transfusions, no effect was observed, moreover, if you transfuse old blood, let’s say, to a rat, then even i would say that accelerated fluid-like aging of the body occurs, several years ago i encountered one ladies, the owner of the golden freaks, who in all seriousness suggested that i do, well, in the community, so to speak, of the club, a telomirase injection, that’s what people call it colloquially , in particular from hollywood, who are guilty of this, in fact, an absolute experiment, i’m actually an imam doctor, so here we kind of had a good laugh together, but it’s based on... the next heresy, when you have replication at the cellular level, naturally, not only the error accumulates, the tails are also shortened, but roughly
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speaking, everything becomes, i would say, the cell becomes more and more inappropriate to the basic matrix scheme, so these people believe that using an extract from stem cells, as i understand it, injecting these things into karatida of babies, you can achieve a very good effect, that is, you will not grow old, this lady was proud of the fact that she... seemed to have internal organs at the level of her students, that she had the uterus of a twenty-year-old woman, that she had something else there, i think it’s natural that to believe in all this, that these are pseudoscientific things, but attention, colleagues, according to her, it costs about $20,000 a year. crazy money, so well, the world's backstage is the world's behind the scenes, so you can't count the money, this is another heresy, it will most likely lead to some very bad results, because in fact people for very big money... are worth experimenting on themselves, on whatever the child amuses himself with, they want to let him entertain him, some kind of secret experiments? no, this is completely unofficial, because the american ministry of health absolutely does not
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recommend this, i will not blame them, there is publication in serious journals like nature, but these are scientific journals, aging concerns gernatology, the problems of gerantology nature, everything is clear with it, but the results naturally remain at the level of just all kinds of crustaceans, forgive rats and drusophila, and only then then you can... anything, up to the leveling of, excuse me, organs in the body with biocurrents, treatment with biocurrents , your own, your own organs of the body, that is, when any organ works for you, it generates a certain field, then when the organ falls ill, then according to the theory of a japanese professor, in their fifties, now i won’t torment you with theories, but you change , let’s say, the frequency of radiation of these microbiota emitted by your organ, and if you take some kind of, let’s say, sample pattern , since a healthy organ is working, it means that your organ is irradiated with this purity, then your organ begins to seem
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to adapt to self-healing, but this is once again on the verge of, i think, unproven methods, they also talk about reduction, that is, they don’t talk, they are studying reduction body temperature, because if we allow a solution of a certain sodium with one other active substance to be introduced into the hypothalamus, then we can lower the body temperature, such experiments were carried out with the drug... by 6°, and by lowering the body temperature, we can theoretically extend our century to 200 years, it was precisely these sorts of things that alexander bogomolets was engaged in, at least in a declarative form, who promised stalin that he would live here for 150 years, it is known that when bogomolets died, as far as we know, from plevoritis, then stalin said, he cheated everyone, why this doesn’t work in practice, it means that the northern peoples should live forever, and the southern peoples should die as quickly as possible. but for some reason the countries with the longest life expectancy, they are mainly connected with mountains, so this is precisely due to the fact that there
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the oxygen concentration in the mountains is much lower, on the other hand there is this famous . when there were all sorts of different documentary projects about doping and about the whole story, that athletes supposedly freeze their blood and then return it to themselves and supposedly this helps too, all this needs to be proven using a completely understandable methodology, we need clinical trials, many, many people, a set of statistics, they don’t do esmen for the sake of youth, they simply increase the number of red blood cells so that they can breathe better for the same time, yes, yes, competitions , that is, it is unlikely that it... how can it somehow influence youth. so, we know that borisovishchal after 5 years, in my opinion he said, no, 5-10, from 5 to 10, 7 years and six months. oh, let's see vladim petrovichava himself, who believed that the secret revealed death. the most important idea was that death was invented
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by evolution for its own acceleration, that death is not... necessary for living beings, that is, evolution wants us to change faster, change, yes, to change faster, and for this it invented death, this this is absolutely against the main postulate of darwin, that everything is decided by natural selection , but also by those who are more fit, i was struck by the greatness of this thought, life was taken away by death, first of all it’s just beautiful, why is aging necessary, why is it a mechanism accelerating evolution? ezob once said that a hare will always run away from a fox, since for him it is a matter of life and death, and for the fox it is a matter of dinner. and he was absolutely right, but in relation to young hares, while they are young, of course, they will run away from the fox, but when they become much older, they run about the same as the fox or even a little slower, and now if two hares meet with like a fox, one is smart, the other is stupid, then
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the smart one will run and get away from it, and the stupid one, in a few seconds there will be an orange beast consider, only then he will run and this may cost him his life, as a very simple mathematical calculation showed, if you have enough foxes in the forest, then in five generations the stupid hare will disappear, well, we rely on you, in short, the terms are known, you told us them , we’ll wait, if anything, we know that several years ago scientists who study the secrets of longevity conducted an experiment on who lives long and found out what they all have in common, you know, it turned out that they all have in common - this is a love of life, a good mood, in general, what they smile often, that they have more optimism than pessimism, which means we need to smile more often, enjoy life every day, and scientists , including russian scientists, continue the work of academician vladimir pitovichav
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, they will help us with this, you promise, everything. we caught the word and agreed, hurray, see you on saturday. hello, the program is about the most notable events of this day. our pilots and air defense forces worked on enemy aircraft four times a day. active defense on the ground in footage from the lugansk front.
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