there was a function called the share a local function and the fireworks will be the accident took place as actually. in the city area where the dollar figure was was born near the track it was average year appear and the people around the gathering would be around five thousand to seven thousand people but. the people who was standing at on the tracks on the railroad tracks actually at the same time and the fireworks was born immediately that they're all coming the. one in from local jail and two hundred first circularly going from research to luck you know what the crossfire at the train and the people did not notice that by the time same to them though the announcers were continuously were given from the state to the people to not come near the fire place so there was a small stamp. for the increase causes the accident and

clearly this is a festival that where people had gathered some thousands of people as you describe that gathered for a celebration and it ended in the most horrific way in this train accident what has been the response how are people reacting there. as of now bald again i must say more than ten thousand people are there that they brag but the bodies already been taken out to endanger or taken out to the hospitals the people those who was standing here now they are educating and they are protesting against the local briar local minutes firm of joe thing to do. right i was there in the function to attend which he was the t.v. at there the people are protesting against her and the minister all fall for the reigning gold functionary without digging for

a reason that is what the people alleging here. well thank you very much for taking the time to speak to us about this story rather than the saying a local journalist joining us there from rights. with al-jazeera life from london much more still ahead more than a hundred people injured in protest this tension flag along the gaza israel border and why a hundred and eight hundred thousand syrian families in lebanon alluding monthly support from the united nations. hello there is mostly dry forests in the southeast and parts of china we've got a good deal of bright weather coming through so shanghai will be at around twenty two degrees to the west there is a little bit more in the way of cloud and rain here and for some of us in the yanks

province i think we're going to have some particularly heavy downpours and they could be a few issues with flooding here toward the south there's also some heavy rain making it towards the northern parts of vietnam if we head out towards the west it looks like the pollution is going to become more of an issue over the next few days because of the season we're in it is stubble burning season and so all of that smoke does cause a major issue and at this time of year new delhi where we see some of the worst conditions that you see not a great deal going on in the weather here and that means the calm situation is just going to exacerbate the problem so for us in new delhi then thirty three degrees will be our maximum but it will be fairly murky as we head through the next couple of weeks over the towards the south that's where the showers are over the fall so the parts of india and through sri lanka more showers are expected here even as we head through the day on sunday for the arabian peninsula we've seen some welcome thunderstorms here in doha there's the risk of seeing a few more over the next few days there's also more in the way of clouds for the western parts of yemen and stretching up into the southwestern parts of saudi.

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welcome back a quick look at the top stories turkish staf working in the saudi consulate in istanbul have been questioned over what happened to journalist jamal khashoggi who disappeared seventeen days ago. turkish security sources say investigators based their search of the consulate on what they heard in those audio recordings. and our other top story this hour more than fifty people have died off to a train plowed into a crowd in india's northern punjab state just outside the capital. where we go to afghanistan now where the elections have been in the southern kandahar province the vote for a new parliament will go ahead in the rest of the country on saturday three years ofter it was scheduled but in kandahar voting has been pushed back a week after a major taliban attack on thursday the delays reportedly to allow for mourning because people would be too scared to vote in the attack a gunman disguised as

a security guard killed kandahar's police chief general abdul razak and its intelligence chief the province's governor was wounded it was just the latest in a wave of almost daily taliban and i still attacks targeting the elections. at least ten candidates are amongst the victims shot at us reports from kabul because after. the military precision for one of the most well known police chiefs in afghanistan general abdel rizieq was overpowered roger general rizzi was a powerful and very respected man and his death is a big loss for us we the people of kandahar all united i will say the achievements made by general abizaid in the past years. as a kid survived many assess a nation of tapes is close to the rank of general but he was also regarded as being tough on the taliban human rights watch it described him as kandahar as torture and

truth in the aging he was involved in human rights abuses of suspected taliban detainees regardless he was well respected by the u.s. and afghan leadership if the loss of a patriot but we remain absolutely committed. to an afghan led afghan reconsolidation. we need to find who's done this. but right now. we are going toward elections and we will continue to defend the camp people the attack happened after this meeting of top u.s. commanders in kandahar provincial it is not long after these pictures were recorded the gunman launched a surprise attack the provincial intelligence chief was killed until americans wounded general miller the man in charge of all u.s. and nato forces in afghanistan escaped unharmed when he returned to kabul image security forces to boost morale he said today's parliamentary elections revealed only this about the attack my assessment is that i was not the target it was

a very close confined space but i don't i don't assess that i was a target the taliban has promised to disrupt the elections and in kandahar it has succeeded. called the by they could out of after the tragic incident in come to harbor took place the afghan independent election commission has decided to delay the election for a week in the come to have province. but for the rest of afghanistan the show goes on all the materials have been distributed under armed guard to more than five thousand seemed his nation wide poll scheduled to open its seven am local on the eve of a much delayed vote afghans must ask themselves what democracy means to them the taliban has promised to attack polling centers afghan and nato forces have promised to prevent such attacks turn out on saturday or tell whoever believed charlotte bellus al jazeera a couple. at least a hundred fifteen people have been injured in gaza with kill him in

a critical condition as protests continue along the border fence with israel seventy seven of the injured protesters were hit by live israeli fire demonstrators have been setting tires alight and throwing stones at israeli troops during friday protests and egyptian delegation has met both israeli and how mass officials hoping to mediate a lasting ceasefire are a force that has the latest for us now from gaza. this friday protest is now winding down you can see hundreds of people streaming along these pathways back towards the main roads here east of gaza city the ambulances though have been going up and down shuttling along these lanes at the same time the whole build up to this protest was in course increased in its delicacy and stakes because of what happened on wednesday the early hours of wednesday morning when there was a rocket strike from gaza in territory which hit and damaged a residential home in the israeli town of. the mother and three children living in that property escaped unharmed but israel has threatened hamas with increased

military action if these border protests proceeded in the way that they have in recent weeks in terms of the number of people approaching the fence breaching the fence lighting and launching in century kites and balloons we did see snipers targeting some of those balloons as they were sent on their way towards israeli territory as for the protests themselves well hamas has called on people had called on people to come out again in force it doesn't want to simply give up on these protests having invested so much in them over so many months and so far having little to show for them however it does seem that there was a call for restraint there weren't so many people getting so close to the fence the center of gravity of these protests remained a long way short of where it has in recent weeks. financial support from the united nations provides a vital lifeline for many of the almost one million syrian refugees living in lebanon but due to limited resources only the most vulnerable people qualify for

assistance programs even some refugees in the position of having their support cut off so hard reports from lebanon's bekaa valley. of the fatah hold myself and his wife hadija have survived the last four years with the help of the united nations they benefited from a cash assistance program for syrian refugees in lebanon but they were recently told they will no longer receive the one hundred seventy five dollars monthly payment so they are victims of what the international organization says is its limited resources. we are in need of assistance from the united nations because we are in deep and i can't work for health reasons i have a heart problem every year the un conducts an assessment to find out who needs help the most the most are always are among one hundred eighty thousand syrian families who will no longer be eligible for the aid which will now be given to the same number of families who have been recently identified as the most vulnerable.

will now be given priority for the first time since her family moved to lebanon a year ago she will be given money to pay for food and other needs. my daughters are working so that we can each that they barely make enough money if they don't work will die from hunger almost a million syrian refugees are registered with the un in lebanon but only thirty percent are eligible for the cash assistance program because of the lack of money. it is our responsibility to make sure that the families receiving this is are really those who need it the most the bottom line is that this program really targets the poorest of the poor and sadly it doesn't even reach the percentage of the families live under the. poverty. now it's a year the conflict in neighboring syria has made millions dependent on assistance . limited funding means many refugees have to rely on themselves and that is not

easy in lebanon where they are not welcome the suffering is immense u.n. statistics show more than eighty percent of syrian refugees have at least one family member living with a chronic health condition. and most organizations provide only basic health care and even the ferries family didn't get that when they lost a child not too long ago they say they have a benefitted from the u.n. cash program during their four years in lebanon the twenty six year old father earns three dollars a day but that is only when he finds work harder nationally she says that came from syria i haven't been able to find a steady job whatever i earn is not enough i have been dead i owe people three and a half thousand dollars the u.s. warns the humanitarian crisis is not going to go away anytime soon and so many continue to appeal for help seven hundred because. mexico's foreign minister is an advise members of

a migrant caravan moving towards the united states to proceed individually if they decide to enter mexico thousands of migrants from guatemala honduras and el salvador have massed in the guatemalan border town of money they expect to cross into mexico shortly as they move north on thursday u.s. president donald trump threatened to deploy troops in close mexico's southern border to stop the migrants crossing into the u.s. . well now thousands of people in crimea have gathered in the central square of the city of at a memorial service for the victims from wednesday's school shooting twenty people were killed when a student detonated a bomb and opened fire at coach polytechnic a suspected attacker was found dead from a self-inflicted wound russian president vladimir putin has blamed the mass shooting on globalisation the use top court has ruled that poland most immediately stop applying a new law which for some supreme court judges into early retirement more than

twenty judges were forced out of their jobs off to poland introduced an age gap of sixty five triggering international condemnation and widespread protests european court of justice ruled that all the judges must be reinstated to that positions forced retirements were part of sweeping reforms introduced by the country's conservative government. when asked the us for thousands of prisoners in california could seek parole under a new system focusing on nonviolent offenders seven life sentences the controversial so-called three strikes law in place in twenty eight states means many people convicted of three relatively minor crimes of automatic jailed for life but as rob reynolds reports the kind that has changed since the mill was brought in twenty four years ago. three strikes and you're out the term taken from the american sport of baseball has been the life behind bars for thousands of nonviolent repeat offenders in california studies indicate nonviolent inmates

imprisoned under the law which was enacted in one nine hundred ninety four are disproportionately black and many are mentally ill some are serving life sentences for offenses as trivial as shoplifting stealing a bottle of liquor or possessing small amounts of narcotics now california plans to allow approximately four thousand third strike inmates to seek parole none are guaranteed release and a corrections department spokeswoman said they will undergo rigorous public safety screening before parole board decisions are made california voters approved changing the three strikes law two years ago but the state's governor jerry brown has challenged the changes in court brown has agreed to drop further legal action lawyers representing nonviolent offenders sentenced under the law called the decision monumental what this really does is it recognizes that some of these people are the lowest risk prisoners in the california state prison system they

have. done it immense amount of programming they've done amends about of education work while they're in prison by by the prison systems own risk assessment these people are disproportionately low risk to re-offend once they're released in the community. state records show that no. third strike prisoners released in an earlier round of paroles were much less likely to commit additional crimes once they were back in society. twenty seven u.s. states besides california have three strikes and you're out laws they were in acted during a time when it was very politically popular to appear tough on crime there had been epidemic of violence due to crack cocaine in many american cities in the late one nine hundred eighty s. and early one nine hundred ninety s. and these laws were passed at that time since then of course the crime rate

nationwide has dropped very significantly in social sciences and criminologist are still trying to figure out the reasons for that decline robert oulds al jazeera los angeles. and just some economic news from china the country's reported its weakest growth since the global financial crisis economy grew six and a half percent in the third quarter down from six point seven percent in the second quarter and that slump is being blamed on a yearlong campaign to tackle debt and the trade for when the united states. just a quick look at top stories for you now turkish staff working in the saudi consulate in istanbul have been questioned over what happened to missing journalist jamal khashoggi turkish security sources have told our investigators listened to already have recordings of his mudda before entering the consulate also says told

al-jazeera that the recordings confirm the washington post writer was attacked by several people moments after he entered the consul's row and they then say khashoggi was immediately dismembered by saudi forensics experts jamal the shell has more. it's important to remember that jamal herschel q when he entered on the tuesday never to be see him again that was not the first time he entered the consulate in istanbul several days earlier he had gone in to process his paperwork he was told by the consul general himself to return a few days later and in our other headlines more than fifty people have died after a train plowed into a crowd in india's northern punjab province just outside the state's largest city. victims was standing on the railway track watching a fireworks display during a religious festival. voting in afghanistan's election will go ahead on saturday but not in kandahar where it's been disposed for a week after thursday's taliban attack a gunman disguised as

a security guard killed kandahar's billie's chief general abdul razak at least one hundred thirty people have been injured in gaza with two of those in a critical condition as protests continue along the fence with israel it comes after an egyptian delegation met both israeli officials and representatives from hamas with hopes of mediating a lasting cease fire mexico's foreign ministers advise members of a migrant caravan moving towards the u.s. to proceed individually if they decide to enter mexico u.s. president trump has threatened to deploy troops to stop the migrants crossing into the u.s. and thousands of people in crimea have gathered in the central square of the city of a memorial service for the victims of wednesday's shooting twenty people were killed when a student detonated a bomb and opened fire at curch polytechnic those are the top stories more news coming up later on now the cure we visited explores a range of medical breakthroughs from bolivia to japan if you stay with us more

news a bit later on by for now. for

some trick of nature these stem cells and white swan are on. which this whole procedure is a bad joke like cupping but it's more sophisticated inside in the reality is that by your body american like isolation. it does mater that worldwide three hundred fifty million people are affected by genetic disorders closed by faulty d.n.a. these genetic defects can lead to a variety of conditions like cystic fibrosis which leads to conic and also cite a long sections and at the moment the system and here i am dr elizabeth healy in the u.k. to see how groundbreaking developments in gene therapy could one day transform the lives of people living with genetic disorders. that may l.l.s.

but not marry bond on a is sixteen years old and was diagnosed with cystic fibrosis at the age of one. america tell me from your perspective what is your day like living with cystic fibrosis. aaron when i asked so i guess op take my interview arises off eyes. and then harass again my x. tears. and i asked you i know now you guys are failing. and they're nasty my physio and. i do spiral a.j. and i'm going to go out and just plain that help me. and then after that ask to do another not be lies well. there are still more process. and then yeah i will need space also you have all known so i learned. that our night.

mary was first diagnosed doctors thought she would only live until the age before. i decided i was dazed and not ready until marriage or. unknown house turned on i thought i'd take the medication the knob ok. there's never a day goes by either and taught everybody forget the whole thing you know live it up so i know it's always there. married to use me to the children that have cystic fibrosis. mark on this our voice if i meet one of them there were no pos i just want to me or on one particular one to em. now you see quite an isolating condition to near yet there's always enough so i now was never so you're haitian now right. so i only used to send your letters to each other or. because they couldn't me face to face on the fly now it's annoying at the moment

mary is not really understanding everything about c.f. she she does now know that it is life show me that she doesn't know that it cannot be kids. but things could be about to change scientists have proven for the first time ever that an experimental technique called gene therapy can improve the health of those with cystic fibrosis i've come into central london to meet the doctors and the clinicians involved in the gene therapy trial and to cystic fibrosis. the rest of it when they come. out english. to stick fibrosis is as you know a genetically inherited disease parents who pass those copies on to their child and they have cystic fibrosis during the first year of life most babies will experience and lung problems and those relate to the buildup of sticky mucus within the airways and that sticky mucus attracts bacterial infections and the bacteria infections become chronic and they eventually cause quite significant lung scarring

in the u.k. around ten thousand people with cystic fibrosis at the moment on a registry about one in twenty two of us is a carrier of the mutated gene most of us won't realise and about one in two thousand babies are born with cystic fibrosis the genetic nature of this and other conditions mean that treatment has focused on managing the symptoms as best as possible but a new and experimental technique called gene therapy replace the faulty gene with a functioning one this is the largest and the longest duration gene therapy trial using a liquid formulation for cystic fibrosis that has ever happened in. two hundred sixteen patients completed the protocol and took at least nine over the course of a year and it was in that group which was defined as being the group we were going to look at that we saw a significant impact on lung function at the end of the year we can thank the patients and their families in the because with patients like mary and her mother

we just couldn't have completed this trial so we're really grateful. these results would not have been possible without the perseverance of scientists who spent years developing the genes and. we started this program and it's thought it would be very easy for patients to just pay out the gene research and if it gets to the right area into the right cells in that lung it turned out that was much more difficult so how are you getting this healthy new gene into the areas in the to do the job of the song teaching. for the try that is just finished but actually using a very simple minded cure it's a pet but we did just use the chin and we mixed it with this chick in this form smaller complex that complex then into the lungs of cystic fibrosis patients the dose of gene therapy that the trial participants received does not determine the correct the faulty cystic fibrosis d.n.a.

but scientists are working on finding a longer lasting solution clinical trial results have been very encouraging but they're not quite good enough to turn them into a treatment yet so we have plans for and as a trial where we get more in depth on gene complexes and more frequently basically in addition to that we have to developed by wrists that this is very very efficient in getting genes into the lungs do you think using fires might be more efficient than using the static possibly using them and we certainly think so based on oil. evidence we have the virus is at least one hundred forty more effective. very frightening. these success stories represent a huge step forward that people might match did you notice any changes cheering the course of the treatment i thought i had no more injury i didn't need well those

charity more k. . were christian traditions back so i prayed still going up just getting a little lot done. and how does that make you feel when you suddenly cheating so mean that a mission where you get to know i could die i die i could do that and i know i can do the hope is that one day gene therapy will be approved for use and widely available to those with cystic fibrosis holders people that are studying and working to get this drug to work even better than it did let's just hope and pray they can get it done and they can get the funding and if it doesn't come soon enough mary she's helped other faithful if it's not to be the next generation of children born with cystic fibrosis. in a city some are. going to begin. by south korea how corning it

speaks for seniors. is that really the sermonize. alymer back again. things can stay there. by the age of eighty five nearly half of us will suffer from oxygen damage to the name which can lead to chronic pain and disability or perhaps because cartilage unlike other tissues doesn't have its own blood supply. so heals very slowly. when i'm in hiroshima japan to meet the surgeon pioneering new techniques in regenerating on the he's. professor mitchell or she is one of the world's leading nice surgeons and a revered figure in the world we generated medicine.

professor to be here selfies way ok thank you. jay tech is an enterprise focusing on tissue engineering and has spent over ten years commercializing professor archies research. and. sourcing. a lot right nice to see you how you very welcome things are paramount. in one thousand one thousand for my dance on paper was published by swedish group the swedish team had developed a way of regenerating cottage in a lab and then re injecting it in liquid form directly into the knee however there

was a weak point all with their technique. in order to solve this problem i started to use very safe. yes you can imagine that. the foot would be here coming up yes exactly. meniscus has no blood supply if injury is the. song we are the light to resect so what you can do with this regenerative medicine is to take the patient's own cartilage from the same joint yes all the change of confidence is essential company i see it does she engineer the cuts. and that's why we're here yeah just half a gram of healthy cartilage is harvested it is then broken down with enzymes and then planted on

a college in scaffold designed by professor ought to after just four weeks the cells will have multiplied to form a four square centimeter disk. the surgeon then makes a template of the lesion and uses that to harvest some perry all still tissue from the shin bone. this will be the cover used to hold the new cottage in place so this is a model of someone's potentially regenerated cartilage but the beauty of it being the patient's own cells here is that it's not rejected you don't need any medicine from the viewpoint i mean you know roger reaction told in a state issue is a topic today this method has an almost ninety percent success rate and is considered a leading treatment fanie cartilage d. fax. what are the limitations of this can it be done better we need a larger scheme. that is in.