entrance inside the consulate a saudi official went out with close of tomorrow. and this video was provided by the c.c. cameras in the surrounding buildings according to high level turkish official i have spoken so there is no way out for saudi arabia but now they have to show us where jamal is bodies buried or kept it will be the key indicator of course now his family is upset we have been speaking to his close friends who have been following who have been the defender of his case since the beginning it took the sure out media platform and they acknowledged to us that they will be f. in a row in istanbul and within one or two days depending on the developments also there will be a common ration in the united states and in the funeral in istanbul many journalists and politicians around the world are expected along with damascus family but now of course the question is whether mr mohammad will be able to get away with the slings

or not let's go now to pass the car in joins us live from washington d.c. some considerable skepticism over the latest saudi narrative what happened to jim marshall job for the u.s. president has already announced that he thinks the statement is credible why. well i think that's the question everybody in washington and probably in all the world capitals are asking democrats have raised the possibility that it's because president donald trump has personal financial ties to saudi arabia but that can't be known because the president didn't release his tax returns and it's unlikely democrats are and he will push that narrow since they don't have control of either house and they don't have subpoena power. there you hear the president say it it's all about money he says this is about arms deals and he keeps inflating the number does seem every day that this scandal has gone on the number of equipment and weapons and where the president put it things that they are ordering and continues to grow from one hundred ten billion to four hundred fifty billion was the comment

he said today along with creating six hundred thousand u.s. jobs i think it's important to point out that that's the white house cannot say where that number is coming from no expert has been able to verify that figure in fact most say that it's a tiny fraction of that amount still the president is trying to make this about an economic issue it's definitely said in the message that he's willing to give saudi arabia the benefit of the doubt so far at least a few here look to the public statements of politicians he's really in the minority on that one important senator senator tim kaine crean out that this is insulting but the president really very much doubling down on exactly where he sees this as of now. u.s. president donald trump spent the day checking out america's most advanced weapons of war and as he sat down to talk to defense contractors this is what mattered most even as saudi arabia admitted killing u.s. resident and journalist jamal khashoggi they wanted four hundred fifty billion

dollars there's never been anything like you know just the last thing i want to do was say we're not going to you know we're not going to supply you with those numbers are actually not true the white house cannot point to any evidence that saudi arabia is actually spending anywhere close to that amount of money for many members of congress they say it's not about the money they say the saudi story just doesn't add up their story doesn't pass the smell test and i think it's high time for congress to recalibrate our relationship with saudi arabia close advisor to the president to senator lindsey graham seemed to point the finger at mohammed bin solomon in this tweet writing first we were told mr khashoggi supposedly left the consulate and there was a blanket denial of any saudi involvement now a fight breaks out and he's killed in the consulate all without knowledge of crown prince the president has made clear he wants to talk to the crown prince he wants

to wait for more facts many in congress say it's time to act the outrage in the united states is mounting the circumstances here are horrifying and the pressure from congress is going to be very great particularly now with the election coming up members of congress going to fall over each other trying to be the toughest in the loudest in saying we have got to do something we've got to punish the saudis the president is reluctant to do that but he may be cornered the president has signaled that he wants to wait would rather not punish saudi arabia with severe sanctions but if congress disagrees it's likely the president will not have the final say. so what's possibly next well there's been a bipartisan group of senators that if the vote what's called the magnitsky act that basically sends a notice to the white house they have four months one hundred twenty days to look into whether or not mr g.'s human rights were violated if so by whom and what sanctions are they going to put in place they don't have to wait those four months they could put together a bill we've already heard senator say they personally were going to block any

future arms sales and senators have that ability and there's also growing talk that there might be legislation that would forbid the u.s. military from being involved in the saudi coalition in the war in yemen we know the u.s. is providing crucial services are such as targeting and also refueling of the bombers it's not at all clear that the saudi coalition to keep up the pace of its bombing campaign in yemen without those assets there's been a move in the past to try and get the u.s. out but with congressional action if fell just short but i can tell you that there is a whole lot of anger in this town over this story if saudi arabia thought that this was going to make it better it might have with the president but not with many other people had to call him that from washington d.c. still ahead on al jazeera police in india calling it of accidents speeding claim plows into a crowd watching the burning of an effigy. hello

there missing a fair amount of unsettled weather across the middle east at the moment our charts shows a fair amount of cloud just in the far northeast this area gradually pulling its way away but there's more cloud out towards the west over parts of iraq and this is going to stick around so i do expect this cloud to give us a few showers during the day on saturday and on sunday we'll see more of that wet weather and it looks like it will turn heavier so particularly for say for parts of northern iraq and through parts of turkey it does look fairly wet during the day at times a bit further towards the south and there's been quite a few rumbles of thunder in qatar recently yet more are expected as we head through the next couple of days to be a good deal of cloud further towards the southwest say for the western parts of yemen and up through parts of saudi arabia will see that cloud and a fair few breaks of rain and those will be stretching across the red sea at times

to further towards the south and for many of us here with a fair amount of weather to you we've got this main weather system here that's working its way through the eastern parts of southern africa and then we've also got this other weather system here that strings its way along and enough into the northern part of our map there this is going to stick around as we head through the day on sunday but in the east should clear and then we'll have a dry day on sunday at ninety. discover new developments in surgery i'm talking about them when i am in hiroshima japan to meet the surgeon pioneering new techniques in regenerating on. a breakthrough medical trial provide some much needed to cystic fibrosis sufferers based on all the evidence but the. least one hundred five might get past.

the cure revisited on al-jazeera. they're watching out to see a time to recap our headlines now saudi arabia has confirmed that journalist and critic jamal khashoggi was killed inside its consulate in istanbul on october the second it says his death was the result of a brawl inside the building we are eighteen saudi nationals have been arrested. two senior saudi officials have been sacked one of them in the last cd was the deputy chief of intelligence and the advisor to the saudi prince prince behind the

man the other man who was. danny was an advisor to the wall. us president donald trump says saudi arabia is announcements of. death is a good first step trump admits that what happened to the journalist was unacceptable thinks the saudi version of events is credible. let's bring you some other news now polls have opened a couple of hours ago for afghanistan's parliamentary elections but it's already been marred with violence and taliban have attacked polling stations in multiple provinces in the southern province of kandahar voters will have to wait an extra week to cast their ballots it follows an attack in the region which killed two senior officials on thursday it happened at a meeting between the most senior u.s. military officer in the country and the afghan commanders among the dead is police chief general of the razak of the taliban has claimed responsibility in this very

ng to derail the election and target anyone who votes it's a crucial poll because saturday's election has already been delayed for three years due to security concerns and voter registration reforms scott live now to charlotte better as she joins us from the afghan capital kabul so are people getting out to vote despite the violence. yes some people but there are logistical challenges so a lot of polling stations haven't actually opened and there are long lines we've heard that there are protests outside some polling stations as people wait for them to open items in the observer this morning who confirmed yes some of these polling stations have an open because the materials inside the polling seem to us has a system that by mitch machines aren't working and that also some of his observers haven't been allowed and so not a smooth start polls opened just under three hours ago on top of that as you say

the security issues as well the taleban say that they would try to disrupt these elections like see them as an extension of american influence in afghanistan and they want to put a stop to them they want people over and over again do not go to vote because we will launch attacks on election day and we are starting to see that just the last few hours so we have confirmed attacks in four separate provinces across the country and unconfirmed reports of attacks and another five in kabul with it she had explosion in the city although casualties are confirmed as another explosion just north of kabul city in gaza need province polling stations close and seemed to have the city you may remember was taken over by the taliban in august they have been to a polling station the can do is mortar rounds of hit two schools and eighty six of two hundred twenty polling stations remain open all those others have been closed because of the techs so across the country the taliban really doing the obese try to disrupt this president gunning on the other hand trying to instill confidence in

my colleague hushmail of our has just been to a polling seem to say that yes it is very tense but there were long lines of people and security was incredibly high so two different two different narratives here. to talk to some candidates and filed a report about from the candidates perspective here it is the popular. i was a journalist before she decided to become a politician a former member of the kabul provincial council she's running for a seat in parliament afghanistan remains a deeply conservative society where women say they are discriminated against but harvey seems hopeful this could be the best chance for women to make their mark in politics. than people even means they don't turn to me. this is the last time you trust me but brokaw and i did broke our

trust and oh really never trust again i mean this is the first time in afghan elections that most of the candidates are young independent and determined to change political lives people like her and say afghan institutions have been crippled by warlords and corrupt officials and that this election is the woman to defeat we want to clean parliament for all these. representatives they misuse their authorities they misused the concept of parliament so first of all we need to bring young educated people with plan how can they build their country. in the past afghans largely voted along ethnic and regional lines but the main political parties are losing their influence and the traditional elite is losing its appeal people here say they are eager to see change there are no job opportunities for us

our people are well educated and the parliament should help create jobs for two teams pull the afghan people on a level so how was the security is getting worse and has to be improved passed parliament's did nothing m.p.'s make all sorts of promises and must deliver once elected. there's been widespread fraud in previous elections so the international community has been pushing for genuine political reforms for them their representative parliament would be the first step towards political stability and reconciliation it's been seventeen years since the fall of the taliban government here in the capital people have been electing their leaders hoping for a better and prosperous country but many appear their dreams won't come true because of the continuing war and the growing disillusionment that may affect voter turnout at a crucial moment. has about about al-jazeera. for charlotte from

security to reform issues. will these elections be seen as credible and how important is that for the future of the government. i've just got to let you know that while that package was playing we actually heard the sound of a rocket being five we believe it's a rocket as opposed to an explosion here in kabul and then multiple sirens over the my right shoulder a lot of embassies we've heard in siren go off in the u.s. embassy in sirens going off from the cities we'll bring you that as soon as we get it confirmed as to what that was going to maybe have to let go and take over at this point we want to keep you in any kind of. you know i think it's more of an alert towards the green zone but in terms of what this election means in general when the americans came in here in two thousand and one that pumped so much money entire international community pumped so much money into

creating sustainable democracy in this country and today is really the taste for the afghan government is can they deliver on this in this climate i mean the taliban minute military analysts say the taliban controls or contests sixty three percent of districts in this country which is higher the highest it's been since the americans came and two thousand and one so in that climate can the afghan government deliver on credible elections today all right sean about a staff in kabul. hi train rather traveling at high speed in the indian state of punjab was plowed into a large crowd killing at least fifty nine people those killed had gathered for a religious festival in the city of amritsar paul chana jan reports. police in india are calling this a freak accident a train plows into a large crowd watching the burning of an effigy at

a religious celebration. the witnesses say the overflow of people pushed some on to the railway track the noise from fireworks prevented people from hearing the approaching train. program. it was a major hindu festival the railway track is close to it and the crowd was huge suddenly some movement happened and the train crossed at that time the. survivors covered the body parts of their loved ones others waited for those injured to be treated at nearby hospitals thanks to crowd was at a hindu festival called celebrating the triumph of good over evil they had just set ablaze the effigy of a ten headed demon from the hindu epic aroma ya know i am at the moment not aware of the reason. being built next to the invitation but the administration should have had a look at it and we were intrigued when i got eduardo and as the investigation

begins the chief minister of the state has declared a day of mourning he has ordered all stated situations to be closed in his real system house a record of safety. twenty three million people use the network the system was build during colonial rule but it is underfunded potsherd urging on al-jazeera . and let's take you through some of the headlines here now does iran now saudi arabia has confirmed that journalist and critic jamal khashoggi was killed inside its consulate in istanbul on her the second it says his death was the result of a brawl inside the building riyadh says eighteen saudi nationals have been arrested and two senior saudi officials have been sacked one of them in the last city was the deputy chief of intelligence and then advisers to the saudi crown prince

mohammed bin sandman the other man who was fired this hour that he was an adviser to the royal court saying of course all has more on the next stages of the investigations. definitely the leaks from the turkish official sources to media really helped to put pressure international pressure over saudi arabia to confess to death. inside general counsel h.b.o. think and has stumbled a turkish prosecutor's office is still following the case very closely and they say since the incident occurred in turkey despite an independent investigation is ongoing in saudi arabia they will be continuing chasing this case and they say they will continue until they find a body because finding the body of jamal is the key indicator in this inquiry us president don't drop those saudi arabia's announcement of death and the arrest made was a good first step i think ohio has more from washington d.c.

from the beginning of this it is than all about the weapons deals he's talking about saudi arabia being a strong ally and thinks that this investigation is a good first step that they're getting close to having a resolution that they need saudi arabia in the region but then he keeps coming back to the deals and i think it's important to point out he is extremely in the minority here if you look at the cable news channels of you look at twitter and all the politicians feeds pretty much every member of congress that is talking about this or saying this story is insane it doesn't make sense it doesn't seem to add up on its face and the knob the news parliamentary elections in afghanistan have opened with a wave of attacks by the taliban across several polling stations in the southern province of kandahar voters will have to wait an extra week to cast their ballots because of last thursday's explosions in the region which killed two senior officials. those are your headlines the news continues here now

dizzier after the cure stay with us. one simple mistake could be fatal. fishing as a deep sea diver carries immense risk to the lives of those willing to take the chance but for a former north korean soldier the opportunity for a prosperous new life in the south with his family was an even bigger risk to take . old marine boy a witness documentary on al-jazeera. it

. was some trick of nature these stem cells like this one are on. which this whole procedure is a bad joke like cupping but it's more sophisticated insight into what our team is sad about your body american like isolation. it does mater that worldwide three hundred fifty million people are affected by genetic disorders closed by faulty d.n.a. these genetic defects can lead to a variety of conditions like cystic fibrosis which leads to conic and also cite a long sections and at the moment the system of cure i'm dr elizabeth healy in the u.k.

to see how groundbreaking developments in gene therapy could one day transform the lives of people living with genetic disorders. that may l.l.s. but not marry bond on a is sixteen years old and was diagnosed with cystic fibrosis at the age of one. america tell me from your perspective what is your day like living with cystic fibrosis. arum when i asked that i guess op take my interview rises office. and then harass again my x. tears. and i asked you i know you guys are failing. and they're nasty my physio and. i do spiral a.j. and they're going to go out and cheerfully in their helping me. and then often ask to do another nebulizer. and there are still more passes.

and then yeah i will need space for city of about an hour or so alone. and an hour a night. but mary was first diagnosed doctors thought she would only live until the age before. i decided i was dazed and not ready until marriage or. unknown house to turn around i thought i'd take them on occasion then of ok. there's never a day goes by either and taught everybody forget the whole thing you know i was up to no so was. married to use me to the children that cystic fibrosis no mark on this of ys if i me one of them they want to pos i just want to me or long passage i'm going to em. so now it's a question isolating condition to near yet there's always knows for sure now is not so you're haitian now right. so and we used to send your letters

to each other or. because they couldn't me face to face on the fly now last night at the moment mary is not really understanding everything about c.f. she she does now know that it is life show me that she doesn't know that it cannot be kids. but things could be about to change scientists have proven for the first time ever that an experimental technique called gene therapy can improve the health of those with cystic fibrosis i've come into central london to meet the doctors and the clinicians involved in the gene therapy trial and desisted fibrosis . the rest of it in fact i'm. adding literature. to stick fibrosis is as you know a genetically inherited disease parents who pass those copies on to their child and they have cystic fibrosis during the first year of life most babies will experience

and lung problems and those relates to the build up of sticky mucus within the airways and that sticky mucus attracts bacterial infections and the bacteria infections become chronic and they eventually cause quite significant lung scarring in the u.k. they're around ten thousand people with cystic fibrosis at the moment on a registry about one in twenty two of us is a carrier mutated gene most of us won't realise and about one in two thousand babies are born with cystic fibrosis the genetic nature of this and other conditions mean that treatment has focused on managing the symptoms as best as possible but a new and experimental technique called gene therapy has sort replaced the faulty gene with a functioning one this is the largest and the longest duration gene therapy trial using a liquid formulation for cystic fibrosis that has ever happened in. two hundred sixteen patients completed the protocol and took at least nine dose is over the course of a year and it was in that group which was defined as being the group we were going

to look at that we saw a significant impact on lung function at the end of the year we can thank the patients and their families in the because with patients like mary and her mother we just couldn't have completed this trial so we're really grateful. these results would not have been possible without the perseverance of scientists who spent years developing the genes and. we started this program and it's thought it would be very easy for patients to just hand the gene research and if it gets to the right area into the right cells in the lung it turned out that was much more difficult so how are you getting these healthy muji into the areas and to do the job of the some teaching. but the try that has just finished it actually using a very simple minded cure it's a fat lip but we did just use the chin and we mixed it with this. this form smaller complex that complex then into the lungs of cystic fibrosis patients the

dose of gene therapy that the trial participants received does not terminate correct the faulty cystic fibrosis d.n.a. but scientists are working on finding a longer lasting solution clinical trial results have been very encouraging but they're not quite good enough to turn them into a treatment yet so we have plans for and as a trial where we get more there is some gene complexes and more frequently basically in addition to that we have to developed by wrists just very very efficient in getting genes into the lungs do you think you see the fires might be more efficient than using the fatty possibly using them and we certainly think so based on noise. the evidence we have the virus is at least one hundred forty more effective fighting very frightening.

these success stories represent a huge step forward that people might match did you notice any changes cheering the course of the treatment i thought i had no more injury i didn't need well those charity more k. . were christian traditions around back so i prayed still going up just getting a little lot done. and how does that make you feel when you suddenly cheating so mean that a mission where you get to know i could die die could do that and i know i can do the hope is that one day gene therapy will be approved for use and widely available to those with cystic fibrosis holders people that are studying and working to get this drug to work even better than it did let's just hope and pray they can get it done and they can get the funding and if it doesn't come soon enough mary she's helped other faithful if it's not to be the next generation of children born with

cystic fibrosis in a city some are. going to begin. by south korea how corning it speaks for seniors. is that really. alan are back again. things can stay there. by the age of eighty five nearly half of us will suffer from oxygen damage to the name which can lead to chronic pain and disability or perhaps because unlike other tissues doesn't have its own blood supply. so heals very slowly. when i'm in hiroshima japan to meet the surgeon pioneering new techniques in regenerating on the he's. professor mitchell or she is one of the world's

leading nice surgeons and a revered figure in the world of regenerative medicine. and the professor to be here selfies way ok thank you. jay tech is an enterprise focusing on tissue engineering and has spent over ten years commercializing professor archies research. and. sourcing. a lot right nice to see how you very welcome things are back. in one thousand nine hundred for my dad's on

paper was published by swedish group the swedish team had developed a way of regenerating cottage in a lab and then re injecting it in liquid form directly into the knee however there was a weak point all with their technique. in order to solve this problem i started to use their the same scale for the. yes you can imagine that. the foot would be here coming up yes if that. meniscus has no blood supply if injury is. a song we are the light to resect so what you can do with this regenerative medicine is to take the patient's own cotton sheets from the same joint yes all the chain the confidence is essential company i see it does she engineer the cuts.

and that's why we're here yeah just half a gram of healthy cartilage is harvested it is then broken down with enzymes and then planted on a college in scaffold designed by professor at chase after just four weeks the cells will have multiplied to form a four square centimeter disk. the surgeon then makes a template of the lesion and uses that to harvest some perry all still tissue from the shin bone. this will be the cover used to hold the new cartilage in place so this is a model of someone's potentially regenerated cartilage but the beauty of it being the patient's own cells here is that it's not rejected you don't need any medicine from the viewpoint i mean you know roger reaction told in a state issue is a topic today this method has an almost ninety percent success rate and is considered a leading treatment fanie cartilage d. fax.