that has been introduced before some type of legislation and at the moment the house of representatives and indeed the senate is holiday they will not be returning until after the midterm elections but what this is is a warning to president trump that they are going to continue to maintain pressure on his administration to conclude its investigation into exactly what happened in the death of jamal khashoggi in the course of the day two comments from a former director of the cia he had this to say referring to the crown prince by his initials and b.s. whether or not he authorized the dismemberment the truth that can brutal killing and torture of him in the reported dismembering of the battery but i don't know but i have no doubt my mind. was fully aware of what was going to happen to be in had approved and the current director of the cia is on her way back

to the u.s. she will be briefing president trump on her return this is the key issue president trump has said he's waiting for all full information from her g. the hospital has been fully briefed it is reported by her turkish counterpart she will have all the information that president trump needs to take a decision as to how the u.s. should react to the death of jamal khashoggi in the u.s. explosive devices and other suspicious packages were sent to top democratic politicians and offices of c.n.n. bill and hillary clinton former president barack obama and billionaire george soros were among those targeted. at a rally in wisconsin donald trump called for unity and said those responsible for the bombs will be prosecuted. the federal government is conducting an aggressive investigation and we will find those responsible and we will bring them to justice

hopefully very quickly the any actual at threats of political violence are to attack on our democracy itself. no nation can succeed that tolerates violence or the threat of violence as a method of political intimidation coersion or control we all know that such conduct must be fiercely opposed and firmly prosecuted a bill schneider is a political analyst he says president trump needs to tone down his divisive rhetoric to bring americans together. trump is a divider he governs by dividing he was he ran for president as a divider he got elected as a divider and he has governed by creating an even exaggerating division in the united states sometimes using incendiary rhetoric when he tells his supporters that

they should beat up protesters things like that he's a divider and he has exaggerated a lot of division in the united states and that can encourage some unhinged character characters to do some rather dangerous things which is apparent apparently what happened some who are trump supporters are saying this is all a false flag and it's being done with the these devices were sent by liberals by democrats in order to blame republicans before the midterm election things have gotten just that out of hand i think the president's responsibility is to try to tone things down to try to diminish the division in the country i don't know the hill do that we'll see what he does at this rally but certainly this threat of violence that came through the mail this is in an invitation to him and to many others in our political life to try to calm things down all right still ahead on al jazeera fears of a health crisis in one of iraq's biggest cities as the water treatment system

collapses. hello there we got plenty of wet weather over parts of the u.s. at the moment if we take a look at the satellite picture we can see one system moving away but it's only being replaced by yet another one and this one includes the remains of a hurricane that recently hit mexico here it is then on thursday giving us some very heavy downpours and then on friday they'll still be lingering across the southeast so they could be a bit of flooding out of this towards the west it should be quieter by the time we get to friday seattle they will see more in the way of rate of top temperature just of sixteen degrees and the hurricane as i mentioned did hit mexico but it's looking a lot quieter as we head through the next few days but a bit of residual cloud with us at the moment and maybe one or two showers there as we head through thursday but generally

a lot quieter the wetter weather is actually further towards the south i think as you head down through costa rica into panama and into colombia that's where we'll see the wettest of the weather but it wasn't all of them for us in parts of cuba should be largely fine and dry as it will be across to make it an across his pond as well if you see a shower here should move away pretty quickly before the towards the south is quite a bit of what weather over south america at the moment that's over parts of paraguay and now working its way across into parts of brazil as well very heavy downpours here more scattered showers to the north of that but the south cool in-born is always a maximum of twenty. the with. wish the world innovation summit for health one community of two thousand health care experts innovators and policymakers from one hundred countries. one experience sharing best practices and innovative ideas. one goal hopefully

a world through global collaboration. apply now to attend the twenty eighteen wish summit. hello again you're watching i just hear a minder of our top stories this hour and the latest fallout over the murder of journalist jim out several members of the u.s. congress introduce new legislation which could end arm sales and aid to saudi arabia. crown prince mohammed bin man has spoken public for the first time about the killing of the saudi journalist. which he described as painful in riyadh the

crown prince said justice will prevail the washington post is reporting that the head of the cia heard all the oh capturing the moment of murder. in the u.s. explosive devices and other suspicious packages were sent to top democratic politicians and offices of c.n.n. bill and hillary clinton and former president barack obama and billionaire george soros were among those targeted. a u.n. investigators say rahane joe muslims in myanmar are still facing genocide head of the united nations fact finding mission on myanmar told the u.n. security council that up to four hundred thousand ranger who remain in myanmar face severe restrictions and repression diplomatic editor james bass. i think it was the meeting they tried to stop russia china and bolivia voting to attempt to block a briefing by the un zone fact finding mission on myanmar china said it was an internal

issue here were even though over seven hundred thousand people fled the country into bangladesh to escape the violence russia said the report of the mission was biased and unreliable even though it runs to four hundred forty pages of searing testimony as the security council veto doesn't apply to procedural matters the chairman of the fact finding mission was eventually able to give his damning conclusions our report characterizes the recent events in iraq one third as a human rights catastrophe that was foreseeable and plan one that will have severe impact well many generations to come if not for ever. the details of the report clearly had an impact on some i never thought in my diplomatic career that i would hear as briefing to the

security council as compelling detail being such awful treatment of a peoples as we have today the u.k. was one of the european countries suggesting the situation be referred to the international criminal court that won't happen because in that case a security council veto could and almost certainly would be used bartz an investigation into the crime of forced expulsion is a possibility because the country so many people fled to bangladesh has signed up to the court's jurisdiction james bone is al-jazeera at the united nations. mehdi has been sworn in as iraq's new prime minister on what's been voting on maggie's proposed cabinet and m.p.'s have agreed on more than a dozen ministers met has been under pressure to form a diverse government under iraq's constitution she has sunny's kurds and other

minorities must all be represented. a doctor's fear two and a half million iraqis are at risk of disease because water supplies and a sanitation system have collapsed in the southern city of basra the breakdown has been blamed on government corruption in the oil rich region rob mattson reports basra is threaded with waterways along which trade has flowed for generations but not now. pictures from the norwegian refugee council show canals choked by garbage and beneath the piles of trash water is saturated with salt. the second mission or she would have been measured early when the water first became salty my brother got poisoned he stayed in the hospital for two days there are too many cases of poisoning it's not only one or two thousands of people that poisoned. upstream dams in turkey syria and iran are blamed for reducing fresh water supplies to a trickle salt water from the gulf has been edging northwards for decades now

bassos top water is on drink coble it can't even be used for washing schoolchildren are among tens of thousands of iraqis who fall in ill health and now that schools have only one place with toilets we always ask the students to bring their own water from home because we had many poisoning cases i've dealt with five or six cases of extreme vomiting you should say because most of my friends can't come to school because of the salty water they have been poisoned some of them got each a skin and some of them got issues with their hair years of frustration with the struggling water an electrical supply is finally exploded in september. with days of deadly protests against government corruption which residents blame for the city's collapsing infrastructure and widespread unemployment despite a visit by high battle of body the prime minister at the time and parliamentary promises that things would improve little seems to have changed doctors and aid

agencies are worried that as the weather gets cooler the risk from water borne diseases such as cholera is rising in the coming days and in the coming weeks when the temperature will be between thirty two and thirty seven it's just very likely that the route will hear we are expecting rates if nothing is done to rehabilitate her and some additional infrastructure says. sits on top of much of iraq's oil wealth and peace in baghdad last year named the city iraq's economic capital but the people who live here say their water supply needs to stop poisoning them rob matheson al-jazeera. a thousands of central american migrants crossing mexico towards the united states have resumed their long trek to the border as the spied a warning from u.s. president donald trump that they won't be allowed to enter the country illegally the issue is dominating campaigning for november's midterm elections in the u.s.

john homan reports from chap us in southern mexico. they resumed their trek at four in the morning trying to make some headway before the baking midday sun even then it was hard work several thousand men women and children dispersed in a long exhaustive trail their goal is to reach the united states a country where they've now become a political football in a bitter election race. with the ability to. take your camera and search. started going to take you john take the camera go into the middle and you're going to find emissary you're going to find middle eastern you're going to find everything and guess what we're not allowed to them in our because we want to say. too much the week with the caravan i want to syria didn't find anyone from the middle east nor terrorists or isis all of which president trump has hinted at

without proof what we have seen a single men women and many families like that of one half year old to say oh taking a breather by the side of the road with her father and aunt they like others here are aware of donald trump's accusations isn't data it's a lie that's your first reaction you feel bad about the discrimination because benard gang members. but what many in the caravan aunts aware of is that the timing of their march could actually turn into a huge political gift for the u.s. president the caravan has inadvertently come just the right moment for president trump and the republican party and that's because the u.s. midterm elections are just too weak. so way and the images of the all zones of people heading for the u.s. border coupled with president trump's inflammatory and unproven remarks are only going to mobilize his support. the one we talked to denied that some criminals

could be mixed in with the multitude it's almost inevitable given the numbers here but they also said that they were heading to the us to escape the violence i'm poverty of back home and to find work so i don't buy the most we asked to be let through so that we can offer a better future for our children our parents who are already held and our families . ultimately the backlash in the us to this movement of thousands of desperate people could push that dream even further out of reach for them and those who come off the john home and i would visit a chop us. it's been called the biggest bank fraud in south african history more than one hundred thirteen million dollars was stolen from the v b s neutral bank leading to its collapse south africa's finance minister has suggested the bank can be saved but if it isn't it is the poor who end up paying the ultimate price for mina miller has more from limpopo province. corrupt and beyond saving that's the

final word in a reserve bank report on the theft of more than one hundred and thirty million dollars at south africa's v b s mutual bank the only black owned bank in limpopo province it was supposed to have been a vehicle for empowerment but instead it was looted being allegedly by more than fifty people from bank executives to politicians some from within the ruling african national congress nor are on the plus why is one of ninety four employees who's been laid off because the bank has no will money for him but. i'm still shocked i don't have a job now i'm very disappointed because they still haven't explained to us exactly what happened but all we know is we don't have a job at least some were douses she deposited her life savings of almost thirty thousand dollars at the bank the money was meant to pay for her children's education she's only managed to get a quarter of it back so it would be better if alistair you know my children cannot even go to school because of all the money i have lost. it's also alleged that

political influences convince local municipalities to deposit billions of dollars at the bank which is against regulations some of those implicated have said they'll pay back the money if they have to others have promised legal action for defamation some are for the report a lie a political thought but for many south africans there are unanswered questions about how such looting was allowed to happen at an institution that was meant to serve them. the bank is accused of granting anyone. get a loan of more than a half a million dollars to former president jacob zuma and transferring more than a million dollars to the brother of this man through. the deputy president of the opposition party the economic freedom fighters the party and both men have denied any involvement the idea of bribery corruption has become part of the south african

cultural deal. so the mess that is going on in secular studies in v.b. as it solidifies of the thinking on the part of ordinary sort of that feeling and corruption is normal government figures last year showed corruption cost the economy almost two billion dollars a year and more than seventy thousand jobs but for people like lisa this is about more than just numbers it's about the loss of her children's future for me al-jazeera limpopo province of africa. as we seek a let's get a round up of the headlines on al-jazeera in the latest fallout over the murder of journalist jim outer shell g several members of the u.s. congress have introduced new legislation which could end arms sales and aid to saudi arabia. the crown prince mohammed bin sandman has spoken publicly for the

first time about the killing of saudi journalist jim out of shoji which he described as painful in riyadh the crown prince said justice will prevail. it would feel. it had to show it will first of all it's very painful to the saudis to all saudis it is painful to everyone in the world it's a brutal attack not accepted investigations are happening we work with the turkish government to reach results of the perpetrators will be brought to justice this is something that has to be taken by in a government and undoubtedly the cooperation between the turkish and saudi government is good and we know a lot of people are trying to seize these painful situation to create a rift between turkey and saudi arabia and i want this place to send a message that you will never be able to do that as long as you have a king good solid man in. it is a crown prince named mohammed in so many saudi arabia. egypt and

a turkish president named to one of the washington post is reporting that the head of the cia has listened to or yo capturing the moment of g.'s murder she's expected back in washington on thursday after visiting turkey as part of a white house investigation into the killing in the u.s. explosive devices and other suspicious packages were sent to top democratic politicians and the offices of c.n.n. bill and hillary clinton former president barack obama and billionaire george soros were among those targeted u.n. investigators say ranger muslims in myanmar are still facing genocide the head of the u.n. fact finding mission on myanmar told the security council up to four hundred thousand revenger who remain in myanmar face severe restrictions and repression seven hundred thousand others fled to bangladesh last year after a brutal military campaign there. those are the headlines we're back in half an

hour right now it's the cure revisited. state. top us think of this story it's it's. ten. wow.

so this is the explosive yes it's basically a wearable robot. research and development in new medicines is costly and time consuming and almost always profit driven so where disease affects only the poor that market is neglected meaning no new medicines. is one such neglected tropical disease it's the world's second largest processor killer off to malaria killing forty thousand people every year but has had no new drugs developed for decades i'm dr when i mean ethiopia to explore how big pharma mobilized in an unprecedented global initiative to find and fast track a cure for. colors are also known as visceral leishmaniasis is a parasitic disease transmitted through the bites of infected sounds like. when

they feed on humans parasites infect the body and the internalised by microfiche is immune cells designed to protect us from infections. here the parasites multiply and destroy the last infecting other. the parasites that move through the lymphatic and vascular systems infiltrating the bone marrow. liver and spleen. symptoms include fever weight loss enlargement of the liver and spleen anemia and the weakened immune system. the disease affects millions across ninety eight countries. lowland rural if you're just north of the equator here due to the hot climate an agricultural lifestyle colors are as endemic . ethiopia learn has more than four and a half thousand patients every year many of them male migrant farm workers working

long hours in the field. with them it's a three to four hour drive to the nearest treatment center but for those are unable to pay for transport it's a long walk. fortunately their destination is a center for the treatment of color. for the last ten years gondar university hospital has been conducting successful clinical trials involving the combination of two all drugs sodium stupid lucan eight or s.s.g. and para myself. in twenty ten the world health organization officially adopted this combination as the new first line therapy for callous in east africa it's the first movement in half a century and dr aramis deros has been leading the way. our previous regimen was so damn stupid to commit for such a few days with

a combination we're able to shorten that arrangement to seventeen days that's good yes indeed and if you could see was more so many factors and so you managed to cure ninety five percent of patients with the new combination is that much better than before well in terms of. more or less similar. but in terms of. hospital hospital base it tends or spittle base to seventeen that's a big achievement. vist to drug combination therapy is safe and has almost half the hospital stay of the earlier treatment. that's a crucial reduction for both patients eager to return to work and the health sector struggling to accommodate everyone currently all twenty six beds here are full. plate everything is love it must be nice to meet if you're welcome this is it yes listen isis research treatments.

after the heavy demands of this year's high season the hospital has run out of power in my city and despite the new w.h.o. guidelines is forced to return to full thirty day regimen of painful and toxic s.s.g. injections. so this is one of old works. he feels very heart fever how long have you had fever. because you know better but. gosh he has been sick for around six months now right. to have pain in your stomach that i think you. know who was first suspected of having malaria due to the similarity in early symptoms. but after not responding to treatment he was referred to another clinic

which finally diagnosed colors are. now six months after he first fell ill he's in good hands but if it was left any longer he might not have been so lucky. patients three more places not able to find. and subsequently when the really weak and. then they go. and now that you're here in hospital. not working how does that affect your earnings as clinician only time can actually understand it's also that there are times. in which they're standing in. at us a nation can lead to. them but who is likely to normalize within a week still like all colors are patients due to the dangers of s.s.g. hill require around the clock monitoring and toxicity testing for the entire thirty

one days of treatment. the new combination therapy is an improvement but until these toxic drugs are replaced entirely by new safer and more if acacias ones it's still not good enough. as a neglected tropical disease. is desperately in need of a new research and development boost. a few thousand miles away help is at hand through a new global initiative. we're here in geneva not far in fighting the un and the world health organization but over here we're going to meet the n.t.i. the drugs the neglected diseases initiative. d n d i r the nonprofit organization behind the s.s. g.p.m. development. founded in two thousand and three with the help of medicines of frontier nobel prize money they've been rallying commercial pharmaceutical

companies around the world to share their resources. already they've gained access to a limited selection of big pharma drug libraries and now have a portfolio of fifteen promising new drugs in various stages of trial for several neglected diseases but now it's a particularly important time for them to see charlie mowbray head of drug discovery is the architect of the all new n t d drug discovery booster a project is. and to access and speed up new therapies for color well it's a great time to visit is an email i'm just about to center for the world's leading pharmaceutical companies ok so after america. ace high qaeda quickly ok you can see here there's a chemical structure or some information here of different ways of depicting the structure or its activity against the parasite also it happens to kill t. crusie that causation i guess so this compound will kill the parasites that cause disease and leishmaniasis really we will have screened one hundred thousand

compounds maybe to find this one they really precious the parasites are really difficult to kill the properties of this is still quite a long way away from what we need for something or long from really become an oral meds from swallow and it'll kill the parasite so we would normally have to start making compounds my hand one at a time really slow really expensive but the companies that have been working in drug discovery for fifty or a hundred years already have big collections hundreds of thousands or even millions of compounds and they're going to have some good look a bit like this one this is drug discovery. d.n.d. i is essentially on the hunt for a look alike to this compound one that may have even better properties for the purposes of a new drug for colors are. but they can't do it alone that's where the booster comes in participating pharmaceutical company has effectively opened their entire back catalogue and what's more they'll lead the search themselves if you persuaded these companies and it's in their interests to do. what i think was many many

motivations but one of the things i like i'm a scientist i used to work for francois pharmaceutical company the people on the other side of this project and no different from me they're really excited about working on a disease like this because we can all see the appalling need here most people want to help and i hope some other companies are going to join this project quite soon so we really want this to be a global console to really name and shame the ones i have inside. where we're working hard with some other companies where you noticed it. it takes a long time in discussions like this we hope some of the companies will join us are great so you're going to click send well i'm just about to do that so so yeah we can send it. and that will be off the wall cloud as in in the u.k. in japan at the end but drugs will be made available at no cost or low cost to the patients that need them so an exciting time fingers crossed. for pharmaceutical giants have so far signed the booster contract which means

d.n.d. i now gain unlimited access to millions of compounds one of the company's astra zeneca is in the u.k. the other three are in japan she knowingly. and days i have received charlie's e-mail with the seat. we're looking for the man who received the email from d.m.g. i i believe is in here and says she is high or low it's nice to meet she let me through that so you look at structure of molecules on computer models as well as in real life technically sure yes you can use only what you do for us that save look out there. if this morning vessels leaps from the bench our structures are no. biggie for us all these are parts that see the compounds and imagine this is the seed that came from the n.d.i. d.n.d. eyes seed is seventeen parts carbon four parts nitrogen fifteen parts hydrogen and

one part chlorine connected into this unique shape. this combination and shape closely fits and binds to a vulnerable spot on the leash mania parasites interfering with their mechanics by so far unknown mechanism but the fit could be better it's like fitting a key to a lock by intelligent trial and error one point zero if the shop for food arrives this is simple ok this is not a sin but you don't have to be a chemist to say that this doesn't look like that so. i would such a compound based on chemical for an update so dan and i took jan your answer so the fact that it's all screening is out romney oh yes it's generally quick around just style a ninety four percent and you can see two rings three rings trying girls and the next one is eighty five percent and so on and so forth that didn't even take two seconds. after a successful scan for compounds with this.