france has seen some of the biggest recent protests over black lives matter. al-jazeera world goes to some of its least privileged communities. where treatment by the police is still a contentious issue. carries a divided city on al-jazeera. the initial findings of an experimental carone are aspirants vaccine go public researches say it's promotes prompts the expected immune response with no serious side effects. peter w. watching al-jazeera live from doha also coming up day 4 of talks in brussels to

decide how the e.u. will distribute $857000000000.00 in coronavirus bailout money. another single day rise in virus cases in india with another 14000 detection is being reported. in china sees its worst flooding in decades the authorities say 24000000 people have been affected. developing story for you that much awaited report on the results of the 1st human clinical trial of a coronavirus vaccine developed by the university of oxford and astra zeneca he is out it has dropped in the past few minutes live now to oxford and our correspondent paul brennan policy reading the report there tell us more. well struct in the last 20 minutes just been skim reading it and it certainly looks very positive indeed although there are some caveats that the report also has put

on it but let me give you the positive aspects to start with 1st of all the vaccine that is being produced by the university of oxford and the general attitude it says is safe and induces in an immune reaction strong antibody and t. cell immune response up to day $56.00 of the ongoing trial that's important because the period covered in this lancet report only covers the 1st $56.00 days this is an ongoing trial but this is just looking at the 1st $56.00 days it was 1077 adults aged between 18 and 55 spread across 5 hospitals between the 21st of april in the 21st of may say this paper covers those 1st 56 days there was a subgroup study of 10 participants which suggests the responses of those antibody and t. cells may be even stronger after a 2nd dose of this prospective vaccine some on

a side effects which appear to be restricted to things like headaches and some tiredness so that's positive as well that said it's very early 56 days not really enough to have a long term view of its of its safety and the report says further safety test sorry for the testing needed to see whether these lab results can be confirmed as effective protection the current trial it says is too preliminary to confirm whether the new vaccine meets requirements such as an ideal vaccine would be effective after one or 2 doses work in target population such as the elderly or people with existing health conditions and to give protection for a minimum minimum of 6 months so they say the current trial too early to say whether it meets those kind of. aims but at the moment the evidence of the 1st 56 days very very positive indeed what's the next stage in this bull. well this is that this is the outcome of phase one stroke 2 as i say because of the

lack of adverse reactions they've already moved to to face 3 so they're on face to face serious large scale which of them are more than 10000 volunteers that's happening both here in the u.k. it's happening in south africa and it's also happening in brazil as well so so halfrek and brazil important because they they are countries where the incidence of corona virus infection is pretty high. and so the efficacy of a prospective vaccine can really be put to the test in those kind of countries obviously once data is coming once data can be gathered from vat big phase 3 then we really do have a better picture of whether this these preliminary findings from phase one stroke to which are taking place on the lab conditions to be fair here in the u.k. have a wider efficacy that really will provide a proper breakthrough in the search for a vaccine against this global pandemic you are telling us there paul that they don't know yet i mean obviously they can't know yet how long this vaccine will

possibly last how long it will give people immunity for and i guess that's one of the deciding factors or components here when it comes to long term testing because if something lasts for 6 months you test in 6 months time if you wanted to last for a year you test in a year's time and that's one of the things that's sort of in factoring into the entire process. and. there is some data from the lancet article from the from the researches that says for example t. cell response peaked within 14 days and that's pretty good and antibody response was within 28 days of this 56 day trial so you know within a very short period really of the the test vaccination being given to these participants to these volunteers a strong response was being achieved it's important to say that the fact that the prospective vaccine does appear to give or to provoke both types of immune response

is also important. attached themselves to the virus that kind of a you know yahn that the lock in the key the joined together with the virus in order to effectively neutralize it to prevent it from infecting human cells other than through antibodies also sometimes act as a kind of flags red flags that allow other parts of the immune system to attack those infected cells t. cells or certain one particular cell that they're looking at his is a killer cell and so it goes and it attacks the infected cells and basically neutralize them and destroys them so the fact that this perspective vaccine is provoking both parts of the immune system in this way is also very very positive news from the research points of view but as a say you know the other thing is the acceptable safety profile tiredness and headaches these are these are really minus side effects so what they do say is that they don't know how strong an immune response needs to be provoked to effectively

protect against the virus so there's a question mark against the dosage there and that's something that the researchers will have to look at exactly how strong the dosed as a human have to have in order to guess effective protection from the virus but that said you know given the. did the details that have been published in the lancet of these 1st $56.00 days of this test a test which is ongoing very positive indeed paul will come back to i suspect in the coming hours and meantime many things brennan correspondent there with that developing story out of oxford. it was their 1st face to face meeting in brussels since the virus pandemic began and talks between leaders were planned for just 2 days but now 27 e.u. leaders are in their 4th day of trying to agree on a virus recovery plan at stake an unprecedented $857000000000.00 deal to help with the economic fallout of the global pandemic but there's disagreement over how it's to be distributed to member states. and if we do this to not meet

a spirit of compromise and ambition is to take the risk of returning to harder times and for some who are concerned about this in the end it may end up costing us even more so i will continue to fight on these subjects in particular with german chancellor angela merkel since as you know we've worked together a lot over the past days and nights natasha butler joins us live from paris natasha hi there welcome back so does miss your macro believe that they can get a deal by close of debating business i guess. well as a good question i mean i'm sure the french president would like there to be a deal as soon as possible i mean he would have been hoping a deal would be reached a while ago because this summit has gone on much longer than expected 3 nights runs of the 4th day as 27 member states try to agree or back

a recovery plan for the european union economies battered by the coronavirus pandemic emanuel mike ross says that what he wants is for the e.u. to show real ambition and solidarity at the time of an unprecedented health crisis and for emanuel michael this is also about the future because what he's been saying over the past few days over the past few weeks is that unless the e.u. comes together now helps we can member states in this time of crisis then many people across the european union will simply look at the e.u. and think well what's the point of being part of it they may turn their backs on it they may decide to vote against it in the future we already know that and c.e.u. parties are rife in the european union and i know mike rowe is warning that if that anti e.u. sentiment rises even further we could see in the future the disintegration of the european union the end of this european union project so he's taking a really long view but of course it is

a crisis or in front of the european union right now as well because we've seen across several member states resurgence in coronavirus cases we've simply seen some targeted small lock downs in countries like spain germany and italy and france people now have to wear masks is obligatory indoors in public areas so there's real concern for the now that amount of micro is saying is also concerned what it will mean for the e.u. in the future how we reach to do you think that's a kind of an inversion point if you will because people can look in on this and what they use trying to achieve and say look you're not fit for purpose because you've got countries like greece and hungary. they've got a position they are not moving it would appear you know we've heard live reports out of athens we've been hearing from mr all band over the past what 48 hours now and you've got people like angle of merkel emanuel macron having to engage with coming up with some sort of deal that may yet be so diluted as to be a tiny percentage of what the original deal was at the beginning of the last summit

not even this summit. well look i mean that's the story of the european union as i said 27 member states trying to come to some conclusion to some unity because there has to be unity in order for there to be a deal on the table at the end look that's part of the process and the obviously all of the leaders of these e.u. nations would know that everyone's coming in with their own concerns concerns for their countries their perspectives and they're just going to have to find some sort of compromise now always nearly always ends up being some sort of compromise the main sticking points here are the size of the recovery plan how this money is distributed you've got more fiscally conservative countries austria netherlands among some kind of saying look we want to know how this money is going to be given if it's going to be given to a country we prefer loans over grants and we would like those loans to have come

with conditions so that perhaps a country is given money but also also to make certain reforms well other countries are saying that's simply not fair you know how are you going to police that if you like it shows a certain distrust of mistrust of other e.u. member states so there's always going to be very difficult to come to a conclusion that is in essence the e.u. but what about all macro is saying and what the german chancellor has said all along is that there's no reason why at the end of this process of discussions there can't be some sort of ambitious agreement on the table ok we'll leave it there thanks very much natasha butler our correspondent there in paris. well the dutch prime minister is seen as the leader of the so-called frugal for states use facing national elections at home and is unwilling to upset taxpayers a step vast now explains from amsterdam. well i mean this the market is playing hard well for sure he's been called all kinds of names like no no that i.

actually seen as the leader of both or it's he's undeterred so. has the backing of parliament here in the netherlands and also a march part of the population a recent survey showed that 61 percent of the population here in the netherlands is not supporting this mccaffery than it's been for a long time already that many dutch people feel that. european country is the conscience so what mark but it's really pushing for is that he came to rome economic reforms in countries where the money is going to go and that's of course a lot of us but it also has elections i'm not that's not a key element here in this whole fight that's right. next year's elections a big competition the right. and the right thing right here and that very risk they also have said they want you to basically ease the road sat and also when elections

and then vote wait. margaret is nathan's hot ball and also. international growth by its of course gating by. india has begun to human clinical trials for a potential virus vaccine these 40000 people have tested positive there in just 24 hours india's total number of recorded infections is now more than a 1100000 from new delhi here's elizabeth purana. the 1st human clinical trials all of a vaccine called kovacs and begin today with 375 people taking part and the director of the all india institute of medical sciences where a large part of the trial is taking place so that regardless of which country comes up with the vaccine 1st india has the ability to mass produce it given its history the fact that it is the world's largest producer of generic drugs and speaking about the situation in the country he said that some places like in delhi where

cases have been coming down for the last 2 weeks seem to have passed their peak whereas other places especially the southern states are going through their peak now now india did record yet another single highest a rise in cases more than 40000 cases and nearly 700 deaths the state of mind remains the 1st the worst affected and with more than 300000 cases now it's tally has surpassed that of spain's it's adding nearly 10000 new cases every day and. the hot spot has moved from india's financial capital by to less developed areas with less medical resources and that is the situation and the concern around the country as the outbreak moves from the major cities to more less developed areas which have this health care infrastructure so apart from maharashtra the worst affected states are in the south they are not and. there are

a number of lockdowns around the country as state governments try to slow down the rise in cases and they're also increasing testing to better detect infections. still to come here on al-jazeera a leading human rights group says child athletes in japan are facing abuse it took me a long time to get well about 6 weeks before i could count to sort of normal again when uniform 1000 patient from new zealand who tells us what life is like for her today. how the seasonal rains have changed their orientation has been heavy rain recently in north korea that's going through to eastern siberia there's a bit of a break in the lives of pulses running through what was around south korea during

tuesday and on the coast of honshu the city pankhurst of honshu on the whole corridor the korean peninsula otherwise is fairly dry much of china as is well the summer rain developing again along the yangtze but i think it'll develop into a big post back into the yellow river valley once more or pass the south the yangtze look fairly dry of course humid and of course occasionally shiny but only occasionally south of that there's a very obvious place maybe off the satellite picture of the city from the full cross where shotokan quite deep and it's not really the philippines or in the west papua but more sumatra and it's to malaysia sudden thailand's a multitude of dark blue there which means big showers probably thunderstorms stretching across into coaching as well not really covering java so larry of significant write bad news here afraid in bangladesh in northeast india the rains become intense again and he's doing the same in the forecast in fact anywhere from northern pakistan to the northeast of india heavy rain is forecast.

talk to old trees there are we as is the government not taking the necessary action to really address some of the structural issues we listen i still think that air travel is the safest mode of travel and to spend that we meet with global news makers and talk about the stories that matter on the older 0. played important role in protecting human. race.

you're watching al-jazeera i'm peter darby your top stories this half hour researches from oxford university in the u.k. say their experimental coronavirus vaccine prompted an immune response to in the 1st human trials the early stage clinical trial show the vaccine did not have any serious side effects and it did produce antibodies. the readers are in brussels for a 4th day of negotiations for a virus recovery that blocks to william dollar budget includes $857000000000.00 to help countries deal with the economic fallout. india has recorded 40000 new coronavirus infections in the past 24 hours prompting an extension of locked up at least 1100000 people another 2 contracted the virus that. the authorities in hong kong have tightened restrictions to slow the spread of coronavirus it comes after the territory reported $108.00 new infections on sunday

the highest one day increase since the pandemic began a dream brown reports from hong kong. hong kong star ferry is one of the city's famous symbols but as with all other forms of public transport here the wearing of masks is now mandatory on board on monday the measure was extended to indoor markets and other covered public places and for the 2nd time 180000 civil servants began working from home hong kong's chief executive warns the new outbreak of cope with 19 may not be possible to contain a thing farm the situation is really critical and there is no sign that it's being brought under control until 2 weeks ago hong kong. had a relatively low infection rate it chief that without imposing strict containment measures has happened across the border in mainland china at one stage the city was recording 0 transmission rates the moods very different now why we worry that we

are close to the collapse because we got more elderly cases more cases we have long term illness and also we found more cases when their wives emergency room they're ready got some new morning changes they are quite ill but since july the 6 there have been almost 600 new cases experts have yet to trace the source of around 40 percent of those infections some medical experts say the new wave of infections points to a loophole in hong kong's quarantine arrangements arrangements which exempt workers like pilots sailors and the drivers of lorries the bring essential food supplies into hong kong from the mainland every day. china's state controlled media offer another view saying recent protests against a u. national security law helped to spread the virus on sunday for local politicians

were arrested on suspicion of taking part in an illegal assembly they were also fined for breaching social distancing laws laws that now make protests like these unlawful adrian brown al jazeera hong kong. ok let's go back to that developing story out top story this hour that news coming to us out of oxford university in oxfordshire the county bucks which are in the u.k. they've had some pretty positive test results of the back of their plans to develop a vaccine against corona virus this is an online news conference where they're taking us through it with say the developments how significant they are and what they think the direction of travel will be when it comes to developing a full vaccine that offers immunity for perhaps a period of up to 6 months or so let's listen in to what's being set. over to terry's our next phase. thank you and just to reiterate everything that has been

said already and reciprocate sighted to see these results as and where this is one step along the way a long journey we are very grateful for all of back sneeze all in tears clinical and not have enabled us to get this are there's lots more testing to do and we're excited to do that if not a bit tired. i'm finally somebody please thanks very much to. echo the excitement of my colleagues but the with the encouraging results my role in that scene has been leading universities efforts to develop a large scale manufacturing program for the bronx a to make sure that we're able to produce or of as astra zeneca are able to produce large amounts of the vaccine supply if and when we get more radical trial results showing that it protects against disease. saw the

production of vaccine for this trial there was a huge effort done by a group of specialists within the universities that same production so it's easy really made a phenomenal effort to make this possible on this timeline but so future work we obviously need to produce much much more than the thousands of those he's. a leader and obviously in focus for today is on the clinical trials. great thank you very much. i must fear concise remarks we will go over than pleased to journalists for our questions. start with nick mcdermott from the sun please thank you tell me next. so

a computer from yemen yes i am quite results guys are very positive as you might point out this is the 1st hurdle probably several. we've got the right one for a good 10000 people in the u.k. . to be given the vaccine but what point will you see a positive signal that is working so how many people have to test positive for the virus in the placebo arm but you just think actually there's something going on here is a protective effect and would we ever see a chinese trial in the u.k. or is just too unethical. perhaps i'll start and then i'll hand over traitor and took that challenge trials i mean i think the answer to the 1st question a is a statistical one and. the numbers that are required in order to

be able to determine whether or not the vaccine is protective is something which actually at this moment is being debated by the international regulators around the world so i can't completely confirm the answer to that question where we can come up with a a number that from a scientific perspective would make sense that we could be able to see a difference between the 2 arms and it's a relatively small number but a critical question that we're going to have to address going forwards is what is the threshold that the regulators and require for this and this is a matter of it will ongoing discussion to have more this morning will stay with those pictures coming to us i suspect on zoom of the scientists on the research people who are involved in what they've achieved so far one step along the way that's the keynote takeaway point on this lots more testing is to be done on the manufacturing they need to produce very very very big numbers along with their

colleagues at astra zeneca they need much more than just the 1000 doses they used in the campaign so far the gentleman there bottom left of your screen he was asked at what point do they decide yes a success or no it's not and in a statistical sense the issue here is that international regulators excitingly said what numbers should be the numbers moving forward let's talk to paul brennan our correspondent following that story for us at oxford university there right in the heart of england so paul this is good news but we do have to wrap it up in a package of is good news and step change right direction but we're not out of the woods yet not by a long shot. no and that's the message that's been put across by the scientists there involved in this research here in oxford the news conference there are really only just getting underway and looking at the clock it's only been going for less than 10 minutes now and they really don't need just in the 1st stages of being congratulate each other and saying how exciting it is that they've got this

far with such positive results but they are actually affective midst of this perspective vaccine is still to be tested on a much much larger group of participants that would be in the phase 3 trials which are still ongoing at the moment that said as we reiterate the phase one and 2 trials of many phase one trial just over a 1000 participants here in the u.k. very positive results indeed antibody and t. cell immune responses have been provoked by this vaccine that they've been given to the participants the acceptable safety profile was highlighted by the researchers in the lancet tightness and headache seems to be the main side effects that they've found so far and the actual but things like the dosage for example how much does a participant need to be given to actually get an effective protection from the virus very much still up in the air and the subjects of ongoing urgent research paul we'll leave it there thank you very much paul correspondent there in oxford.

ok that's the desired track of the fight against covert 19 what about the reality of covert 19 we've heard about the efforts to combat coronavirus what was it like to actually have the disease joining cross and has recovered from covert 19 she's based in new zealand she told us the impact it had on her. to be honest i don't remember the whole that i think my brain is block some of that because it was quite traumatic. it was very scary i had a lot of anxiety through it i remember feeling very sick but it was so unknown and . the time time heals all wounds as you can imagine and for months on life is moved on from somewhat of new zealand so i feel very very fortunate for where i'm sitting today i was in hospital for 4 days and i was nice lation ward i was one of the 1st hospitalized patients in new zealand i think a lot of that might have been course it was very early days and i was relatively

high profile enough to look after me in the hospital system wasn't i below those but i was i had a terrible. risk terry issue and my chest was just i was really struggling to get enough it through and i couldn't stop the coughing and it was coarse and i'm on 7th and so they were keeping a really close eye on going i took me a long time to get well about 6 weeks before i sort of normal again but the lingering effects have been substantial to the point of i've actually had a situation this wake for him to make sure it's this which i haven't had a flare up in a long time. having had a hysterectomy last year i didn't expect if i had one of the end and there was some research around inflammation in the body and the connection from cocoa trying to make sure cysts courses early days and no one really knows i had to come off a loss and suffered other people i had to use a binge once my lungs i'm so strong as they used to say. that i've noticed that they change i'm certainly had a lot more x.

and pains in my body but to be honest i don't really know how to attribute it drake i mean the lungs are the only thing i can say that are related because i did not have that beforehand and everything else i really don't know how i'm going to have to get those answers and or if i ever will. i've. come if you're just joining us your top stories for searchers at oxford university say their experimental coronavirus vaccine prompted an immune response in the 1st human trial the early stage clinical trials showed the vaccine didn't have any serious side effects and it did produce antibodies india has recorded 40000 new infections in the past 24 hours prompting an extension of locked arms at least 1100000 people and to contracted the virus there the authorities in hong kong have tightened restrictions to stop the spread

of the virus the territories leader carry lamb announced the measures up to 108 new infections were confirmed on sunday the highest one day increase in cases since the pandemic began. e.u. leaders are in brussels for a 4th day of negotiations for a coronavirus recovery plan the blocks 2 trillion dollar budget includes $857000000000.00 to help countries deal with the economic fallout antigovernment protesters in mali have descended on the capital bamako demanding the president's resignation they're blocking roads and their burning tires a day after an opposition coalition rejected a compromise plan from west african mediators to rental rain and rising river water levels of swept across southern and central china at least 140 people are dead or missing nearly 24000000 people are affected by the worst flooding to china in decades those are your headlines up next it's talk to al-jazeera i will see you very soon but i. global pandemic mass protests demanding change

economic recession and geopolitical tensions not to mention the small matter of a looming election join me steve clemons in conversation with leading voices on the bottom line your weekly take on u.s. politics and society on al-jazeera. the all who. would say. he's one of the most divisive figures in american politics today to some he's washington's most famous warmonger to others a fearless defender of u.s. interests john bolton's decades of conservative foreign policy have influenced the position and actions of the united states in conflicts worldwide. from iraq to iran syria and north korea to mention just a few. ever since 1st serving on the president ronald reagan's administration back in the 1980 s. bolten built a career as a solid conservative republican politician.