the open flags you made said den livelihoods and bring life to watch your senses. this is just the early days, then of the month and a prediction vol. that'd be god of the effect of climate change focused on once again, maybe in the eye of the stall come out of the data, the whole, the, this is out a 0. these you top stories, the foreign ministers of tennessee and libya have discussed what they call the regular migration of the 1200 migrants have been left stranded. the middle food was so shelter all around it, up into mizzi and box to the border, and they've been bought a gods of refusing to let them in human rights watch of jesus to this. he is not lacing international by collective expulsion supplies, migrants the representative in the west bank and gaza has told out to 0 that

israel's assault on jeanine this week that killed 12 palestinians was this proportionate on a breach of international and international delegation is assessing the damage cost of homes and infrastructure. it's a very dramatic military invasion. we have seen of between the 3rd and the 5th of july and invasion, which was not a, an attempt to restore law and order. it was actually an attempt to massively destroy the areas suspected of how bring some of the elements by foot disregards of the proportionality of the immediate reaction in relation to the objective, a raleigh's going ahead in paris to own it, the death of

a black man who died in police custody in 2016. but as despite being bound by french officials, another protest is being held in law say of the police coming of the teenage at night owl 2 weeks ago. his death spunk purchase of rights across from the governor . if you questions don't you ask region says that at least 7 people have been killed in a russian broken attack. russia struck a residential area in the city of 9 on the dutch probably minutes. democracy has handed in his resignation to the king. villain alexander, step down off to his coalition. government failed to agree on a new migration package. right, those are you headlines as always the website as is there a dot com to check it out for lots more. stay to the stream coming up next of july on i just thing goes to the post office, the local election, sort of shift to the right click the country with nice another here with the in

fall, right? government 11 piece meets the indian women, breaking down gender barriers as they fight to become champions. features the coast african need is from across the continent as well. so seeks to strengthen relations with the region. people in power focuses on somalia as a fight for survival. as years of drafton hom conflict have combined to create a humanitarian disaster. as to security becomes increasing global concerns. the united nations launch is a report examining food crises and tongue around the world to live on a jersey to the high us any okay. sites are watching the stream. that is a wholesale to say you a and biotech research that is dedicated to i've a slowing all stuff in aging. what would you like free? like if we didn't age, is that even at the cool?

we have a panel of experts. so that's kind of what scientists you are going to be here to answer your questions and your concerns. you can put your comments right here in the comment section, and i'm currently agent. i'm really starting to get ready for the year. i a 277. that is to get like october, november, december, free. for the month i do age. the progress is to reimburse the page that has happened so that i can be to stay in bylaw until age. we all know how much money that our bank account we know how much we weigh. we know how many social media follow early on. we don't know our speed of aging, but how fast are you a in a solvent? if you had an aging point, like your bank account would, you spend a certain way is if we have aging points, we have an a bank account, then society could shift instead of us saying we're going to be a martyr for wealth or status or whatever would it change in that balance a little more be about human. so maybe coming to fast about when he becomes this b c's acknowledging that was brian johnson. he has, he's 45 years old,

but he really wants to achieve of my logical body of 18 years old. is it possible to stop aging or with us aging? joining us to discuss this, we have mingo, as a physician, scientists and directors, the aging center university of california, los angeles, with us from bell, great sab, yet peter fetish of founder and chief science officer at jerad. i'm joining us from berlin. andrew, still scientists right to an over the age of the new science of getting older without getting old. is that possible? i'm good. always chasing somebody that actually is it possible with phone we live a certain amount of time with age of with fortunate enough to live long enough and then we die. how can you disrupt? i think the most important message i want people to come away with tonight is this isn't science fiction that can sound like science fiction. and i think the best way

to demonstrate that as well, let's think about what aging is best. if you're a human being your risk of death doubles about every 8 years. this is because of the increasing risk of diseases like cancer and heart disease and stroke, leaving killers in the modern world. as that means that may at the age of 37, i've got i won a 1000 chance of dying this year and i quite like the results. but unfortunately carry on doubling and doubling and doubling a number. it can eventually get very big very quickly. so if i'm lucky enough to live into my ninety's, i'm lucky enough that we haven't made any breakthroughs, nation biology, in the intervening time, my risk of death and one of those years will be one in 6 months of life and death that the roll, the dice on so it is to, to stickle definition of agent is doubling of mortality, right? every 8 years. that's one way of understanding the aging process. but if we look around the animal kingdom, there are the most, he's risk of death. it doesn't change them out a whole day all around a most like tortoises, certain kinds of paste certain kinds of liquids like solomon this, these aren't capable of living, but they apparently don't get old. they can literally get older without getting old . and so i think there's no reason biologically, according to those of physics,

where we couldn't apply the same piece to watch to we age name. that's certain questions that come up in this conversation that we don't need to ask ourselves. we just accepted. what do we age? what is the scientific reason the humans aging? well, there are many ways. it's just that, oh, pick out i'll come, i'll come right back to me. i'm going to get, let me go 1st and you go 2nd fax. this me? yes. so there are multiple reasons that we would potentially when it gets aged. so one is biological reason, so there are machinery in our body, no longer works so well, because we pay attention to for taylor t. so from a lucian already standpoint too, we humans as a speech, these are the most important, it's activities of life to propagate. after certain propagation that

are there is no strong evolutionary drive to keep us. wow, because historically we live, you roughly about thirty's to forty's and then we pass because then the resources can be said for your generation. however, right now, life has changed due to technology advancement. we have the resources to support more people. so this is sort of a philosophical argument as well as biological argument. so. so usually we, yeah, i strongly believe that we could reverse aging because this is obviously reverse aging or expand live. yeah. is a long dream over several centuries, but we in the past we failed. but however, when i was a ph. d student at university of california, san francisco,

one of my favorite professors, cynthia, came in, wanted to expand, extend the life spam starting from a little worm known as c elegans. so these worms lived for 2 weeks. and then what she did is she asked if she could extend the life span of these worms when she introduced gene mutations. as you could imagine, i was skeptical at 1st. however, shockingly, she did it, she and other colleagues of the other scientific field found that she and they were able to double the worms, maximum life span. interesting. they this extension is full for life span and how span not only do squirms flip twice as long. the 2 weeks old worms, which wouldn't be dead now appear useful and robust with robust movement. so

and then install that would normally leaves a brain degenerative disease no longer did so. so then that would be the equivalent of a 160 years old in schumann. yes. right. it would be a really but healthy. well, let me bring in pizza for one low, and i'll come back to guess. this is free to own on twitter. and i want you to understand what he's mission is coming over here to twitter on a mission to significantly extend huffy human life span. sadie is really important the the, the was, it jumped out to me was healthy human life. i pay the what do you want to add also, so 1st of all, i will probably close out of option less thumb is increasing the depo a life changing the cost might be a 1000 years ago. okay? probably expandable after 30 years old. but now it takes 30 to 40 years old, just social nice a way of each of the goals of our profession, spine,

40 years old. when houses are we are starting to, to, to, to decrease, excuse by apply or the last or how many peers i would watch from almost doubling. it's not because too much decided to come along for all my life fun is because i have to call gen social changes. it takes longer for us to develop to socialize, and that's why i would use some i will combine it in such a way that we do like all in development on waste time. but we're life amount of completeness. just knowledge of groups that are a life, some even more. so you're asking about vision. important things here is that humans too much company page can be young can for you, or they can be open for help with this plan with them that is age. so age is kind of normal, so nobody, you know, don't stop the gymnast agencies like that. but if you have diseases, you'll have medical interventions. so i think the data context that does it cutting right now is that people start to get aging prior to it until the disease unplugged to home to, to everyone you're supposed to. so agent before does it stop purchasing us?

they bought some features that policies for we function, regular sites all we, we unfortunately, she is a lack of moment, easiest, most, mostly in physics, as colton. topic is mostly not the deductible, is where they have to go to my uncle bill, which is pretty low century concerns for any most important thing is like a jumpstart page. as someone, most of my interests are stopping. i think somebody will stop aging and maybe a few minutes here. i just want to make your revolution. i must apologize for now. i have to use all day reliable biotechnology and i'll just will stop agent right now on to the doors about this topic right before she use it. let me just bring in a voice from out poor to community. this is aubrey. the grey. as she talks about what one of our biggest challenges right now as a human race is this is aubrey told us that yeah, more than 100000 people die of aging every day. and they do so after a long period of debilitation and decline. and now that is the number one problem

across the world, even in the poorest countries of the world, because every country has an average life span of at least 50 now. so we absolutely must address it with that i can say, and i'd like to say, but we're all making progress, but we need to make progress much more rapidly. we're getting some really interesting questions angel unusual. i can also take on this one, and one of of us says a key part of a healthy life is being able to accept via thanks show ality of death. trying to take her away into a tunnel you for being a multiple is a waste of time, a fast and a waste of us trying to maybe be a see a spiritual power rosalyn accepting that with me humans that sub created is i know i'm sure you're nothing, so i'm going to choose a very, very quickly to have that conversation with,

with some of our peers i'm doing. he stopped putting you guys 2nd. yeah, i think that this is a very common question like actually, and i can completely understand where people are coming from when they ask this. but the challenge is that when you're thinking about treating aging, most of us on super interested in and we'll tell it to you and i go over some generally sweat off and ask about actually what we care about as this, with me mentioned earlier, it's health spine it's about the amount of your life that you can spend free from disease. so going to come so as a disease essentially caused by the aging process, heart disease is essentially caused by aging. stroke out time is dementia. all of these diseases, the leading candice, the leading causes of suffering as it will be mentioned in the modern world are caused by this process as biology that we call aging. and so we want to tackle the aging process to remove that suffering. and people will live longer because they don't hang on well as a result. and she necessarily think that's a bad thing. i think you know, death is a tragedy. there is, um, you know, you never go to a funeral and say, oh my god on go have they died. it really gave that life. meaning. i said just to so a story that we tell ourselves to try and justify the fact that we do, you know,

we do eventually golden die. and i think that as we, you know, we do have to accept that human beings. but we shouldn't accept the suffering that comes along with it. and that's what aging biologists really care about. basic i had, i was just, uh, think about the world in which uh, national, just uh can i start the quote on those quote uh, leave for another 10 years more display stories i ended up in europe. another modem to me, i think today would be fine too much already. justin gmc time of booking about 1005 extension to well think about the world where steve jobs probably for another 10 years. i think what the agent essentially uh, did you say out the most successful or professional uh from us uh, those guys have own change. so total complete value traditionals, which means. busy agent, uh, thank solid commercials for you. don't want your life trip and just on the wall it's not true. the under the personal decisions also huge economic things. and also

guys, look, we don't die. so i'm kind of your wrestling. this is just as much as you would, you'd, reason will die from jumpstart, as, as much as we used to have as the you're, you're still do. but think about dimension. and then just think what happens if it don't stop agent kind of what would be the amount of truth on some software at all . let's towards this fantastic african problem that whenever someone dies, a library buttons, i just really kind of just the fact that, you know, all of his knowledge is wisdom is accumulated in life experience or the social connections, everything just up in smoke. i mean, not really to crystallize is what people are saying or what is human tragedy of aging. and yeah, because of the oil tradition of some traditional societies. well that hopefully you pass that on to the next generation. so your library lives on the, in a younger generation being let's be very specific about what is being done right now. that is relevant to us aging in terms of drug technologies and research. what

he told us about the one getting an extra, like doubling life span, but when not once, so was going to help us write now. hi. oh, great question. so what i was trying to say is to stop 18 or extend my span is possible, this work was done 30 years ago. and as my colleagues have already told you about, there is a lot of work that has been done to extend healthy spend in animals. there is no reason to believe that humans, we don't work that way because in many other circumstances, we humans just use the same kind of tools and more. that is to say, right, but what is the actual research that's being done? so we understand that there's certain animals that get older, but they don't age a well, you've managed to double it sliced by. well,

what about us right now as an aging population around the world? what is best for us right now? so they are better let me get, let me, let me have a little chat with me and then i'll come back to you. so of course, there are several ways to answer these questions. there a potential medication interventions. there are also a lifestyle interventions. so with a common goal to reduce the disease of aging, the burden of disease of aging. so which are heart disease, cancer stroke, dementia frailty, also preserve per process and increase propensity for infection and so on, so forth. right now, the medications potentially that are not necessarily approved or anything and then more work needs to be done. the intriguing, intriguing possibilities are related to an event medication known as met foreman,

which is antibiotic medication. by certain retrospect, to studies in the literature, it appears that it would potentially reduce the propensity to develop heart disease, cancer, and so on, so forth. currently, there is a large truck back to clinical trials that is being planned on to formally address if this medication can be really reversing. h of other studies including medication. no that's from mice in which has being shown to affect aging in animal models. so those are just, are we talking about mice? thing are we talking about next to mice can become, i'm sorry, was none of these makes no perfect. what can we, i to be formally proven to delay aging in humans. yeah, those are interesting. be that the research community following through our piece

out, what do we have right now? what are you working on right now to extend a healthy human life span? oh, i just, i wanted to bring up this edition study month, which is called part of yours is where it was full and the picture can connect us up ration system. so if you don't come to the mice will trap a situation where they're able to march to get the younger and the unfortunately, the younger marshes, just molder. so that clearly factors are someplace in practice in my block of mice, at least that could be associated as agent question. do you want control age which i've been using, right. you. busy sense of humor, of blood samples. and we identified the fact that they should have moved from the shop collision naturally stand slash from the mice and forget to just television victory on monday. or don't have to have a pool that this was for consumers as well. but essentially what impact or engage

was a mattress and one big crowd to share of the younger, blocked, at least. so we're looking for electrical solutions that are going to do what are some punch getting staging quickly, sweating late in life. all right, pete says you were to, hey, andrew was making a face out. it was a good face or 5 face. articulate your face, andrew guide. there was a good face. i'm very excited by this stuff because we have literally thousands of ideas on the table. and the way the i often try and write these down is to think about something called the whole marks of the aging process. i know it's because biologists finally have some really strong ideas for the on, depending. so you not my life cannot biological mechanisms because us to grow old. these changes in our biology that happened as we age on the pin. the whole gamma of age we like to change is not just the cancer with heart disease of the story from the dementia, but also the ring cause the grey had frailty, the incontinence. all of these different things that happened to us as we get older, are fundamentally caused by some collection of biological changes. so to give them a concrete example, one of these hallmarks is accumulation of what i called the semester so semester. it's just a so technical term for old and these are cells i've been speaking with the current

of your body for a long time. and as a result they've stopped dividing. yeah, i want to still, i'm always on task sticker, 100 nation. can you, can i show it it's about so that yes, all right, hold tight and that one good piece of pick up of the back of this video. this video came from a bio take organization. they're trying to make a book on drugs to stop senescence. and andrew is just about to explain what some essence is. but next let the animation do that as i've look. you may not feeling that as your body ages, it can be an accumulation of malfunctioning so school semester, which is likely to many common age related diseases. seasons head cells, they begin to a nice, large quantities of full protein causing inflammation. tissue. a differential worsening of underlying conditions, et cetera, rate tissue damages disease. so i'm really proud of. i know it's an essence,

is andrew, please continue to select the yes and the animation shows you what's going on inside all of our bodies. all of the time the semester is how it's coming to being mnemonic. it's weird why the cells not potty imaging. this talks it comp time with molecules if you now think excellent. all right, smart truth might be, oh that the aging process. the answer is, according to the mean system to assign higher, hey, i'm a dysfunctional, wholesale can you come and, you know, clean me up and then a young person, do you mean system is very effective? it comes in, clears out the sinister cells. there's no problem as we get older, the cells accumulate more and more quickly. and also one of the other hallmarks of aging is a reduction in the efficiency of our immune systems. and we've all seen already, you know, tremendously powerful example of this in the last few years when we saw how much older people were much greater deceptive of de, from a disease like carrying a virus. because our main system is a week or less able to find that often unfortunately. but the immune system is also i, i could sort of a police force within our own bodies as well clearing out the scent sense house. and this might be a very depressing story. sondra so identified some cause of aging. but the good news is scientists of also identified something that we can do about it. which is

that we can give these things called the senate electric trucks, these and drugs that kill this. and i some cells believe the rest of the sounds of the body intact uncertainty. so given these to mice industry and what they found was they basically made these mice biological younger site base a bit longer, which i guess is a good start if you're trying to site on the aging process, but not stretching out the frailty at the end of life, these animals that they get us disease, they get less cardiovascular disease because most of that comes to fuel cataracts, of that less frail and a healthy a. so if you stick them on a treadmill and then the mice and this time you must always treatments or using the experiment can run further in foster on this treadmill, often by taking the drug that appears to slide on cognitive aging. and frankly, it's worth doing a web search, or some of these are some pictures of these animals because you do not have to be an expert to see that the animals i've had this in essence how treatment i just looked fantastic because take effect, i got this great physical part of the skin based this looks like how do we order, fantastic looking mice running around. all right, i and i want to bring in the voice of charles brenda because we've been talking

about how are we able to look at as was anti aging. what is that out there? and charles wanted to make this point. let's bring him in and then we can talk about it personally. aging is it normally process required to convert fertilize a to a mature reproductively capable. adult agent is not a disease. you're going to eat better with good nutrition being mentally and physically active. and basically, following mom's advice, you can age worse by whole reading, drinking smoking, taking non prescribed drugs being violent situations. unfortunately, there's an incentive structure in science that has rewarded height in the anti aging space. and it is not at all clear that one can directly target the aging process as a drug approach, despite what's your viewers may have heard. so is that is tells contradicting

everything we've been talking about the drugs conte help us. just, i'm just going to get you to do to also read it briefly cuz i've got some questions as well, from my view as me. but yes, what charles has been mentioning is a very good point in the sense they are some pharmacological interventions. but most probably more importantly would be lifestyle interventions. and so what i'm seeing here is about certain diet, certain size activities, not no talk sense, including smokes, better, sleep, a good amount of stress, but not bad stress. yeah. social functions and so on. and so for okay, may or i've already made as long as i think some questions for my views and they really came to talk because you've read in spots and thoughts. this one is for you piece and it can very quickly on youtube. how much will this cost? is this kind of technology available only for the wealthy pizza incident reaction?

go ahead as well. it did not the. busy cost to launch the cost, you'll have to make the customer then they don't customers. think about that. quite honestly, for 20 years, 10 years is required to do your clinical trials. 10 years plus these will be a genetic buck with no cost. okay. all right, this one i know 1st question andrea, what are the possible psychological and emotional effects of living longer on? definitely bulletin anxiety depression. this one is going to andrew, i'm just going to say 30 seconds being all types 100. i think this is so he just dramatically ever played actually because we think it's going to be this huge transformation of the human condition. but i just want you to think about how you conduct to your everyday life. how many of your plans are predicated on the fact you're going to die in 20 or 30, or 40 years in the future? people to obviously cited for time and i've got pension, i think mostly we live, i live some day today. if we happen to be healthier for longer, our friends and family were healthier for longer. this would be a fantastic thing. we've just carry on living our lives as we do now. and i bridge,

i think this idea are getting bored holes much water. all right, you've made me so here's my me saw piece of we are out of time, but it's over us from was conversation as so much more to talk about much more research to take and really appreciate you being pita, andrew and view as on youtube for your excellent questions, i'll say next time, take care of your body, the the mediocre, you know,

as the correct can call me this revel only to be disappear of families. tragedy entwined with a violent chapter in the country's history. when you see the, let's say, is that going to be my blood on that was to a knife long search for answers and close finding salon. witness on out his ear showing you here is coming over our heads from russian positions and new cranium. positions familiar with the been sending about how they were directly targeted as they were trying to sleep. we've seen some of the residents come out of the building with that possessions in suitcases by substantial safe anymore. what happens on that day is a war crime shows how many regions across the lines and the level of destruction here, food just how fits the fighting has been in recent weeks,

this russian or don't some on a street has been a place of pilgrimage for centuries. the . ready ready on the hello, i'm signed these i them, this has been use our lives from del, coming up to the next 60 minutes. we'll have the latest live from tyrese's product test as plans and latest out fridays police findings. and from an easier accused of rounding up hundreds of black african migrants and leaving them stranded on the border with olivia and the u. delegation is in the occupied westbank to assess the damage pools via as well as assault. im jeanine monsoon rains trigger floods and lance lives in.