this is bbc news. i'm clive myrie. the headlines at 11 — china and russia have called for a freeze on north korea's nuclear weapons programme, following claims it's successfully tested a long—range ballistic missile. talks have broken down, to restore the power—sharing executive in northern ireland. sinn fein has blamed the deadlock on theresa may's political deal with the democratic unionists at westminster. the family of the youngest victim of the manchester arena bombing, saffie roussos, has paid tribute to her today, on what would have been her ninth birthday. we've lost everything, we have. life willjust never be the same. most cancer patients should be offered dna tests to help select the best treatments for them, according to england's chief medical officer. britain's mark cavendish pulled out of the tour de france after breaking a shoulder in a crash on stage four. and on newsnight — an extended report from sicily,

on the new wave of migrants are venturing across the mediterreanean, on the anger in italy at those helping recuse them, and on the reaction of locals to the migrants that arrive. good evening and welcome to bbc news. north korea has tested what it says is a missile capable of striking anywhere on the planet. the claim, if confirmed, raises the prospect that pyongyang, may be a step closer to its goal, of having a long—range nuclear strike capacity, and able to target america. the united states has requested an emergency meeting of the united nations security council to discuss the missile launch. meanwhile, china and russia have called for a freeze on north korea's nuclear weapons programme.

here's our diplomatic correspondent james landale. this is the moment that north korea says it came a major power, the launch of a missile which it says can deliver a weapon as far away as the united states. the news was announced on state television with barely constrained joy- the presenter showing the handwritten order given by the country's leader, kim jong—un. he personally supervised the launch of a missile which he believes will secure him in power, protect his people and dismay his opponents to the south. translation: if north korea ignores our military‘s warning and continues provocations, we clearly warn that kim jong—un‘s regime will face destruction. this is the missile that could carry the regime's nuclear weapon.

it was launched from an airfield here in the west of the country. it was sent up at a very deep angle and it rose, it is claimed, to about 1700 miles, thought to be the highest any north korean missile has got to. it then landed 37 minutes later, more than 500 miles away, somewhere in the sea close to japan. the key point is that if this missile were fired at a shallower angle, it might now have the power to reach, potentially, more than 3&00 miles, the minimum defined range for an intercontinental ballistic missile. if so, that could mean reaching as far as alaska on the mainland of the united states. they're so keen on developing more advanced missile capabilities. although right now, the region is targetable, it is about ensuring that they have that level of respect stand up and listen to us.

experts say it is still not clear if north korea has the technology needed to protect a warhead on re—entry and guide it to its target. but the possibility of north korean missiles reaching the us is a significant step forward, which president trump said earlier this year just wouldn't happen. in a tweet, he again urged china to put pressure on north korea to end this nonsense, once and for all, a message echoed by allies. the government will be escalating this at the 620 and the un in the next few days. but the real pressure has got to come from china. but so far, china has been reluctant or unable to turn the screw on north korea. president xi was in russia today. both he and president putin called for a freeze on north korea's

nuclear weapons programme, but also the suspension of us and south korean military exercises. but this supreme leader is enjoying his growing nuclear capability and shows little sign of listening to anyone. the balance of power is shifting in the region, and the outside world seems powerless to stop it. the latest round of talks to restore northern ireland's power sharing executive suspended since january, have ended without agreement. the dup says it wants to continue discussions over the summer. sinn fein has blamed theresa may's deal at westminster with the democratic unionists, for the failure of the talks. what this constitutes is a monumentalfailure in what this constitutes is a monumental failure in behalf what this constitutes is a monumentalfailure in behalf of chorizo may. she has set back decades of work that has been done here throughout the years. —— theresa may. it is a consequence of the dup supporting the prime minister and interned the prime

minister and interned the prime minister supporting the dup. minister and interned the prime minister supporting the dupi minister and interned the prime minister supporting the dup. i want to send the message very firmly to the people that we represent that we are still here, we are still try to find accommodation. what we want to see is an agreement which everybody can buy into whether you are a nationalist or a unionist. i think that's important. michele 0'neil of sinn fein and arlene foster of the dup. the youngest victim was just eight years old, amidst the horror of the manchester bombing in may that killed 22 people. saffie roussos would have been nine today and her family have chosen the occasion to speak to the bbc about what happened that evening at the ariana grande concert. some of those who survived have life—changing injuries — saffie's own mother is still in hospital. judith moritz met the family. singing voiceover: saffie roussos shone. always singing and smiling, she loved music, and couldn't wait to see her idol onstage. you couldn't be out with saffie without having fun. but her dream was to be famous.

it was her everything, and we bought her the tickets for christmas. she was just counting the days, the seconds, and it was just ariana grande ‘til nine, ten o'clock at night, and she would sing and dance every single song. she was ariana grande obsessed, so, to see how happy she was, it wasjust... obviously, i had to go with her. you were watching her watching ariana 7 pretty much, yeah. she kept going, "come on, ashlee, you promised me you would get up and dance!" so we had a little dance. and she wasjust so happy, just elated all night, grinning. saffie was at the concert with her mum, lisa, and sister ashlee. they were all caught in the blast, just as the rest of the family arrived to meet them. i remember i was thrown to the ground, and then my next instinct, ijust sort of rolled over and crawled, because i couldn't walk.

for you that night, andrew — had you come to the arena to collect? what were you doing? we were sitting there, weren't we? forjust a few minutes, and didn't hear anything, butjust... just hell broke loose, just people, children, screaming, crying. and then, as i turned round the corner, i saw ashlee outside injured. and when did you learn about saffie? the detective that i spoke to in the hospital, he went away and he came back about 12, half 12, and told me. and you've all had to cope, haven't you, with saffie's loss and also lisa's recovery? yeah. how is she doing? she's fighting. i mean, she's got that many injuries around her body, just that alone. she's like a soldier. yeah. the world knew what had happened. lisa was not conscious. no. and when she came round, you had to tell her. no. she looked at me and said to me, "saffie's gone, isn't she?"

i was dreading it. she just looked at me and said, "she's gone, isn't she?" and i said, "yeah." she goes, "i knew." do you have thoughts about the person who did this? no. i've not seen pictures, i don't want to know. i'm not interested. it doesn't mean anything to me. no, same here. if i could think about it, analyse it, break it down, sort it out and get saffie back, i'd do it — but i can't. how are you finding it? there's times when you're sad, and times when you're happy, so it's kind of like a mix. you met ariana grande — tell me about that experience. i wanted to meet her to tell her what saffie meant to her, and i wanted to tell her from a father's point of view that she's got nothing to be sorry for. she's got nothing... you know, it wasn't her fault. saffie's family say she'd have

been a star one day. now, her name is known, but for the saddest of reasons. we've lost everything. we have, because life willjust never be the same. judith moritz, bbc news. most cancer patients could be offered genetic tests within five years to help create more effective, personalised treatments. that's the ambition outlined by england's chief medical officer. in her annual report professor dame sally davies says there needs to be a national network of genome testing. here's our medical correspondent fergus walsh on how genetic testing could bring about a change in medicine.his report contains some flashing images. hello, mate. could i have two cappuccinos, please? cancer runs in toby knight's family. both his parents died from it and he was diagnosed with colon cancer four years ago. now, he's one of 31,000 patients who have had their entire genome

mapped by the nhs. i'm very excited about it. for me, hopefully, if my cancer decides to come back, it will benefit me. more importantly, it will benefit a lot of other people, forfuture generations, for better treatments, for quicker treatments, better diagnoses. dame sally davies says genome testing is still a cottage industry. she wants dna analysis to be the norm for cancer patients within five years. patients will benefit if we can offer them the scan of their genome that'll make a difference to their treatment. that's clearly all people with rare diseases, of whom there are three million or more in this country. it's most patients with cancers, and quite a lot of infections. 0ur genome contains the instructions for how our bodies work. errors in the dna code can trigger disease. six out of ten cancer patients who have genome analysis can benefit from targeted treatment — drugs which attack dna faults

in their tumours. this can spare them the more toxic side effects of chemotherapy. it costs £680 to scan a genome, and that price is falling every few months. in some cases, it's now cheaper than existing tests, like invasive biopsies. but what about data confidentiality? the nhs believes it can protect genomic information, but some are concerned about the safeguards. if you're going to take a lot of very sensitive information from people, then you need to make sure that every use of it is consensual, that people have choices and can make choices, that it is handled safely, that you've got security, rules that are applied around who can access it. the more we learn about our dna, the greater the potential for new treatments and even cures. concerns over sharing data will need to be resolved if patients

are to get the full benefits of the genome revolution. fergus walsh, bbc news. britain's mark cavendish pulls out of the tour de france with a fractured shoulder blade after a crash earlier today. cavendish says he was elbowed 150 metres from the finish line by the world champion peter sagan who was disqualified. cavendish finished the stage after receiving medical treatment. the bbc is to spend an extra 3a million on new content for children over the next three years. the corporation says it's facing increased competition from companies such as facebook and netflix and it wants to offer more online choice for young people. it's expected it that will include more video, blogs, podcasts, quizzes, games and apps. now on bbc news it's time for newsnight with evan davies. it's summer, and it is the season for the next wave of desperate

migrants to try and cross the mediterranean to europe. in parts of italy the strain is beginning to show. we want to defend europe from immigration and multiculturalism. the issue now? ngos trying to save migrants from their precarious boats are being accused of facilitating people smuggling. and there's new friction between european countries. if europe couldn't handle migration effectively two years ago, or last year, can we expect it to do so now? we'll ask the italian ambassador. the government promised to rehouse all the grenfell survivors. but are residents accepting the option being offered to them? the second one was near a very busy road and that was not sitting my needs. gay pride has come a long way from this in the ‘70s to pride in 2016. as this weekend's march approaches, we ask a veteran of the lgbt movement what it took to get

from there to here. hello, europe, again, predictably, finds itself enmeshed in arguments over a migrant crisis. it is true that last year, it did manage a deal with turkey, that closed the eastern route from syria to greece and beyond. but that still leaves tens of thousands of people this year, taking the route up from libya into italy. those numbers cause friction in italy itself, and border tensions too. today austria announced that it's ready to deploy troops to stop migrants entering.