request a huge rally in barcelona as hundreds of thousands demonstrate against independence for catalonia. a week after a vote on breaking away from spain, these protestors say they want the country to remain united. we want to stay together, we don't want to break the country. i am catalan and i am spanish, and i'm here because i'm proud, but i don't want catalonia to go out of spain. we'll be asking how the catalan and madrid governments will act amid spain's worst political crisis for years. theresa may says she's determined to carry on as prime minister as one of her predecessors calls for an end to tory infighting. the new gene test that could mean fewer women having preventive surgery because of their breast cancer risk. and a last minute goal, but heartbreak for scotland as they fail to qualify for next year's world cup finals. good evening.

hundreds of thousands of people were on the streets of barcelona in a huge show of support for the unity of spain and against plans for the independence of catalonia. spain's worst political crisis for decades was sparked a week ago by a referendum on independence for the wealthy north—eastern region. it's home to around seven million people. its government had said it planned to go ahead with a declaration of independence in the wake of the vote. but spain's prime minister has warned of drastic action if that happens. from barcelona, our europe editor katya adler reports. cata la ns

catalans who oppose independence from spain call themselves the silent majority. today they made a lot of noise. we want to stay together. we don't want to break this country. i am catalan. i am spanish. and today i'm here because i'm very proud. and i don't want that catalonia go out of spain. everyone we spoke to here was cata la n everyone we spoke to here was catalan but people came from all over spain, in the name of spanish unity. this crowd is emotional, excitable and passionate because this is all about identity. their identity. whether catalonia remains in or outside spain but the power of emotions aside, today is also all about politics. the question here for the spanish prime minister — will he wait for

the catalan government to declare independence, or act the catalan government to declare independence, oract first. the catalan government to declare independence, or act first. his a nswer independence, or act first. his answer — in a rare televised interview today... translation: be absolutely reassured, the government will prevent any declaration of cata la n will prevent any declaration of catalan independence from turning into something real. spain will continue to be spain. it is what the majority of spaniards want. maybe but catalans remain split fween familiar lanes friends where tensions remain this week. i'm worried independence will happen in 48 or72 i'm worried independence will happen in 48 or 72 hours and i haven't heard have a clear expansion of how things are going to woncht i don't know if i'm going to be in europe, ifi know if i'm going to be in europe, if i will be using the euro. we have two countries, spain and cat lonia. my heart is divided, you know. i'm excited with the idea of creating a new country but i'm worried, too. my

friends are very, very worried. but ardent pro—independence catalans aren't concerned. they're elated. they view the spanish government as oppressive and identify with the cata la n oppressive and identify with the catalan language and culture, not spanish. . we are waiting for a long time. last week catalans held an independence referendum not recognised under spanish law. so now will the catalan government fulfil their response, announcing independence risk a strong response from madrid. talking to an mp from the governing party that seems increasingly unlikely, a kind of "yes. .. but.". we increasingly unlikely, a kind of "yes... but.". we are sure and we have understood that the majority of cata la ns wa nt have understood that the majority of catala ns want this have understood that the majority of catalans want this country to be an independent style. we are ready to

talk, negotiate with the catalan, with the spanish government, in order to make this effective. it does not sound like a unilateral declaration of independence. this is the point. but by now the point from many catala ns, whatever their political persuasion is to avoid deepening divisions, between fathers and sons, colleagues and cousins. after days of colourful flag waving, a heartfelt plea for vile og. —— for dialogue. kata joins us now. what happens now snchlingts the catalan government right now is walking a tight roe. dancing a delicate dance between the promises it's made to pro—independence—minded catalans and the knowledge that if it suddenly declares independence this week it do last for a few hours, because under spanish law the spanish government can take away the

autonomous powers from catalonia and govern this region from madrid. politicians in catalonia are aware that big businesses and banks are unaring scared of the idea of cata la n unaring scared of the idea of catalan independence, if they leave this region, it'll impact the economy. we have to bear nibbed the inside the catalan parliaments, the pro—independence—minded parties are a fractious and disparate bunch. and when it comes to the all—important next step of whether to declare independence, views is fluid and fast changing and full of false rumours. what can seem ioo% certain tonight can change again tomorrow. theresa may says she is not someone who gives up, despite moves against her by some of her mps in the wake of her faltering party conference speech. the former prime minister sirjohn major today accused those conservatives who are seeking to undermine her of being self—absorbed and disloyal. here's our political correspondent chris mason. after a turbulent week, a chance for

quiet contemplation. the prime minister and her husband arrive at church this morning. theresa may wa nts to church this morning. theresa may wants to be seen to be getting on with it. by this afternoon, she'd swapped a pew, for the streets of her berkshire constituency. she told a sunday newspaper her calamitous conference speech was "uncomfortable" but should be kept in proportion. one minute journalists are accusing me of being an ice maiden or report then they claim i'm a weeping woman in dire need of a good night's sleep, she said. the truth s "my feelings can be hurt like everyone else, but i'm pretty resilient." enter next, offering support, this man, sirjohn major, who knows what it is like to bea major, who knows what it is like to be a prime minister under pressure. it is time to put up or shut up. he saw off his internal critics two decades ago. now he wants to help

theresa may do the same. those undermining her, he said, were "undermining notjust undermining her, he said, were "undermining not just their undermining her, he said, were "undermining notjust their party but the government, too." and from a former prime minister, to a future one, at least in the dreams of some tory activists. both with the same message. we've seen some quite unfortune tune ate shenanigans of people trying to push, but the pushbackis people trying to push, but the pushback is strong, we are behind the prime minister, she is the best person to lead us forward. reporter: are you fully behind the prime minister? the foreign secretary, seemed to be perpetually in the running for the top job and mrs may's chief irritant said today those trying to topple here were nutters but could or should the prime minister sack or move him.“ you put back boris on the backbenches he will take to the hustings, all over the country and all over the media. the only way you can avoid leaving him as foreign secretary, with all the difficulties

that's created is to give him a job which is essentially domestic, but you give anyjob to boris and he will still be boris. downing street sources say talk of a ministerial reshuffle is speculation but some say it is time for theresa may to freshen up her team in terms of a reshuffle. because she's staying and because she's going to remain in thatjob and we want her to remain, she has to come out fighting next week. one of the things she will have to do is assert her authority. one of the ways to do that is to have a reshuffle and bring in some of the brilliant talent. tomorrow, mps return here to parliament. the prime minister will be reassured that a series of tory heavy hitters and others have rallied behind her. but, it is an indication, too, of how precarious her position is perceived to be. the row between the white house and american football players who've been kneeling during the national anthem in protest at racial injustice has resurfaced.

the us vice president, mike pence has walked out of a game in indiana because some of the players knelt. president trump tweeted tonight to say he's proud of him. let's get the latest from our washington correspondent, laura bicker. how did events at the game unfold, laura? well, this looks like a very much planned walk—out by the vice—president. it should have come to no surprise to mike pence that the players on the field, the san francisco 49—ers knelt during the national anthem. they have done so for the last three weeks. in fact it was one of those players that started the debate in the first place. so, as the players kneeled during the national anthem, mike spence, stood next to his wife, hand on heart, waited for the anthem to finish and then he walked out. and with that swift walk—out he has reignited the debate between the nfl and the administration. president trump took credit, said it was his idea and that he was proud of his vice—president. he relishes this

row. because it plays to his blue collar, rough belt base, who take pride in the flag, take pride in the national anthem. for pride in the flag, take pride in the nationalanthem. forthem, it comes first. but if it was a sturningts it was a risky one. not only could it stoke further division in this country. it could've been costly. the vice—president took air force 2, which costs hundreds of thousands of dollars, an expensive stunt to basically score points for tap scheme trump. —— team trump. president trump has promised to, in his words, "take care" of iran. in a television interview, mr trump again criticised the agreement, negotiated by his predecessor, president obama, which lifted sanctions on the iranians in return for the country restricting their nuclear activities. i believe they're funding north korea. trading with north korea. i believe they're doing things with north korea that is totally inappropriate that doesn't pertain to the deal. but in my opinion it

does because it's called the spirit of the deal. and you will see what i will be doing in the not too distant future. but iran is a bad player, and they will be taken care of as a bad player. the snp leader nicola sturgeon says she won't think about the timescale for another scottish independence referendum until the brexit deal becomes clear. she had previously talked about holding a second vote as early next autumn. and, as the party gathers in glasgow for its annual conference, some believe its focus should shift to a second referendum on brexit. our political correspondent iain watson reports. the political weather has been changing in scotland's largest city in recent years. once a labour stronghold, the council is now run by the snp. and the majority of voters in glasgow backed independence in 2014. earlier this year, nicola sturgeon suggested there could be another independence vote as early as next autumn, but in this city this morning, her timescale sounded

far more flexible. there are many people i think in scotland who desperately want to see scotland become independent. there are others who are not convinced and who'll never be convinced and there are others who perhapsjust think we need a bit of dust to settle on brexit. what's changed ? well, the small matter of a general election where the snp lost one—third of the seats at westminster and now at this conference, an snp conference, remember, independence isn't even formally on the agenda and privately, some of the most senior figures in the party are saying... don't expect to see a second independence referendum before the next scottish parliament elections in 2021. and here's perhaps the reason why the snp leadership are reflecting on the timescale for independence. is it odd that independence doesn't feature as a formal item on the agenda? well, you know, we are damned if we do and damned if we don't. this is the party of independence. of course we have the brexit bill coming back to parliament.

we need to make sure we are arguing for our national interest in that which is about staying in the single market. so the snp say their immediate priority at westminster will be to work with others to oppose conservative legislation on leaving the eu but some seen area party figures are saying privately that they should go further, that the referendum they shoulding arguing for, isn't won on independence but on brexit. and that seems to reflect the view of pro—independence voters here in glasgow. no, i think she should just hold her horses and kind of wait. i wanted independence. i wanted to stay in the eu. however, i think the people of scotland have kind of spoken. this autumn, expect the snp to continue to put clear blue water between them and the government on brexit. but also expect to see far less focus on a second scottish independence referendum. the man arrested after a car crash outside london's natural history

museum yesterday has been released by police, but remains under investigation. the 47—year—old was one of 11 people hurt when his toyota prius mounted the pavement and hit pedestrians. police said the incident was a traffic accident and not terrorism related. scientists who've developed a new gene test for breast cancer say that it could cut the number of women having surgery in case they develop the disease by a third. the test‘s been developed in manchester — if proved successful, it could be rolled out across the nhs. our health correspondent jenny walrond's report contains flash photography. they have a friendship forged through a fight against cancer. charley and annie were tested for the brca gene mutation after losing family members to breast and ovarian cancer. charley was a carrier and given up to an 87% risk of breast cancer. annie wasn't but was told she had a 50% chance. as a result, both had masectomies.

87% is pretty high, so to me, ijust wanted to get rid of them as soon as i could. had the risk been a bit lower, i would have maybe thought twice about it and been a bit calmer about the situation and perhaps gone for regular screening, as opposed to such drastic surgery. i always thought that they would kill me, so ijust wanted them off. so, it was all to do with that mindset, really. no, it is a big operation and it is something that is life—changing. the women's chances of developing breast cancer could have been much lower, but it wasn't possible to tell. charlie has the same bracajenas angelina jolie who also had her breasts removed after being told she

had a risk of breast dancer. —— breast cancer. this test looks at 18 variants which influences the chances of breast cancer, including other age fact rs including breast density and the age of puberty. some scientists think it could cut the risk by one—third.“ you can get the risk below 50—50 women are much more likely to take chances, have screening and other preventative measures than a mastectomy. scientists believe they'll be able to give a breakdown of any woman's lifetime chances of developing breast cancer, using up to 300 genetic variants. developing breast cancer, using up to 300 genetic variantslj developing breast cancer, using up to 300 genetic variants. i think this new gene test could be a game changer in trying to prevent breast ca ns

changer in trying to prevent breast cans by giving women early warning that they carry a genetic risk. perhaps even if it's never been in theirfamily before. perhaps even if it's never been in their family before. and scientists are also investigating whether this research could also be used to understand the way our genes affect our chances of developing prostate, ovarian, lu and c kol yoen rocketal cancers. “— ovarian, lu and c kol yoen rocketal cancers. —— rectal canners. now, with news of a world cup qualifier which broke scottish hearts and a win for lewis hamilton, let's cross to lizzie greenwood—hughes at the bbc sport centre. thanks very much. good evening. there was heartbreak and hope for two of the home nations trying to reach next yea r‘s football world cup. northern ireland booked their place in the play—offs.

more on that in a minute, but in ljubjana, scotland, knowing only a win would do, couldn't keep alive their dreams of a first major tournament in 20 years. chris mcloughlin reports. wherever they go, there's usually a party. but in terms of the football, they really get their hopes up. skom on scotland. until now. each and every one of these fan has an individual tale of world cup qualifying woe but at the end of a campaign that at one stage looked lost they are daring to dream this time it dobb different. the equation was simple. the task was not. defeat a side who'd yet to lose a single goal at home during the entire campaign but this is a new and improved scotland. a scotland unbeaten in five matches. a scotland with celtic striker, leigh griffiths. i—o. one almighty roar. clinical but will it be crucial. the 4,000 celebrated and dared to believe but it was far from complete. i—i, back to the knife edge. this was the moment yet another world cup dream looked to drift off into the night. the striker‘s second, was it the end?

almost, snodgrass provided hope but no fairy—tale finish. almost, snodgrass provided hope but no fairy-tale finish. it's been an honour to work with these guys. at the moment it is disappointment but my disappointment is nothing compared to the players you saw them at the end. i don't think i have seen a group of players that exhausted and disappointed at the end of a game. for the fans all horribly familiar. 20 years and ten major campaigns without qualification and it hurts just as much every time. well, scotland's downfall meant northern ireland were guaranteed a play off place despite losing to norway. in the end they drew in oslo. meanwhile group winners england used theirfinal game in lithuania as a useful chance to try out the youngsters. our correspondent natalie pirks reports. one home nation's heartbreak was another‘s joy and northern one home nation's heartbreak was another‘sjoy and northern ireland could afford to enjoy themselves in norway but the home side wanted in and when michael mcgovern slapped at and when michael mcgovern slapped at a cross, it gave an own—goal

headache. a sloppy end to a brilliant campaign. the green and white army know urgency will surely return in next month's play—offs. england's place in russia was already guaranteed, so the likes of harry winks and harry maguire were handed debuts but when dele alli was brought down it was harry kane who stepped up again. gareth southgate says his team lacked big players. he can not stop scoring. kane might beg to differ, the 99th—rapged side in the world had their chances and england's i—o the world had their chances and england's 1—0 win followed a tried and tested formula of being deserved yet unconvincing. so this is how group f looks at the end of their campaign. england top, and scotland just missing out to slovakia on goal difference. northern ireland finished second to germany in group c. and they'll be hoping for a favourable play—off draw later this month. lewis hamilton is on the verge of winning his fourth formula one world championship. the briton eased to victory in the japanese grand prix,

while his nearest title rival, sebastian vettel, was forced to retire. hamilton's lead is now 59 points with four races to go. that's the sport. there's of course lots more on the bbc sport website, including news of claudia fragapane's bronze at the world gymnastics. back to you. a look at the papers coming up next on the news channel. this is bbc news. teams from around the world are competing in an 18 hundred mile solar powered car race across australia. the world solar challenge aims to showcase technology that could one day be used in commercially available cars. the race begins in the northern city

of darwin, crosses the country's desert heartland and ends in adelaide. last—minute checks for the 3,000 kilometre race from the top of australia to the bottom. 41 teams, mostly from universities and big business but also some high schools are competing to see who has the best solar—powered vehicle. the field is so far apart. all the cars look different. all we know is we have a good car, we have it running perfectly in the last couple of days and we are confident we'll do everything it takes to win. held every two years, its event organisers want it to inspire the brightest young people on the plan tote help develop sustainable transport. overtaking takes a lot of energy we would otherwise not want to use. we feel very happy to be in third where we don't have to overtake that many cars leaving darwin. it is a gruelling journey from darwin in the north, to adelaide on the south coast, travelling across the dry, hot, unwelcoming outback. the vehicles must almost

entirely use the sun or energy derived their own movement. they are allowed a small battery but it can't be replaced unless the vehicle breaks down. travelling by day only the race is expected to take a week with most cars reaching speeds of 90 to 100 kilometres an hour. the fastest time was in 2009 by a japanese university. the feastest cars are expected to reach adelaide on thursday. now the weather forecast with phil. bot about the benign weather set to continue into the first part of the new week. there has generally been a lot of cloud across the british isles but at least it helps to keep temperatures up overnight. not too much of a system for the new day on monday. temperatures in many towns

and cities will be noe double figures. not the most sparkling the starts. a lot of cloud across a good pa rt starts. a lot of cloud across a good part of scotland with the odd bit and piece of rain as well. for northern ireland, something drier, perhaps, but still the odd spot of rain possible on the breeze. generally speaking across the greater part of england and wales, dry weather around and bright continues, too. that won't necessarily be the case in the far south—western quarter, the air is moister, cloud will sit low on the moors of the south—west and there could be drizzly bursts of rain. i'm hopeful as the day gets going, some cloud and rain will dissipate and it'll brighten up, up into the north of england, parts of scotland too as weather fronts pull away into the north see. i have not forgotten you northern ireland, you started not too badly. the cloud thickens up and into the early part of the evening you see rain which is the moment at which, in wales, away from that rain, we should have a decent evening as wales take on the

republic of ireland in that crucial world cup qualifier. a wet night in store from monday to tuesday, across the northern half of the british isles but the same weather front that brings the cloud and rain as it slumps further south through tuesday, nothing more than a band of cloud with the odd showery burst. following on behind skies brighten nicely, temperatures close to where we have been of late but no escaping the fact more cloud and rain to finish the day and northern ireland, and these weather fronts accompanied by strong winds, notice the isobars, they'll bring heavy rain for the western hills of scotland, cumbrian fells, top end of the pennines and eventually the welsh mountains. not too much in the way of rain for the south and east and east anglia and brighter skies following on behind, setting us up for a decent thursday and friday and into the first part of the weekend we could actually see a return of some warmth after that speu a return of some warmth after that spell of wet and windy weather. this is bbc news. we will be looking at tomorrow's

papers ina we will be looking at tomorrow's papers in a moment. first, the headlines. a huge rally in barcelona as hundreds of thousands demonstrate against independence for barcelona. the spanish prime minister says he would not rule out anything within the law. theresa may insists she's determined to continue as prime minister, despite moves by tory rebels to force her to resign. sirjohn major has called for an end to disloyal behaviour within the party. scotland's first minister, nicola sturgeon, says britain's struggles to chart a way out of the european union are boosting the case for scottish independence, but she wouldn't commit to a date for another referendum vote. scientists develop a new gene test that could mean a third fewer women having preventative therapy because of the risk of getting breast cancer.

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