in many parts of the uk, with a warning of more to come. roads were closed in a number of areas hit by snow, and there's a storm bringing heavy rain over the weekend. a huge blaze during a birthday party at a popular restaurant in mumbai in india kills at least 1a people. the dog who's had pioneering treatment to save a leg from amputation — experts hope to use the same technique soon on people. and rain stops england's push for victory on the fourth day of the fourth ashes test. good evening. snow and ice have led to another day of travel disruption in parts of the uk. passengers at glasgow airport faced delays after heavy snow caused flights to be suspended for a while.

there was snow too across northern england and the southern pennines. the rac has warned that driving conditions will be very difficult, if not impossible, in the worst—affected areas. our correspondent judith moritz reports. grounded at glasgow — flights at the city's airport were suspended after snow settled quickly overnight. the airport reopened by mid—morning, but managers have apologised for the knock—on disruption which was caused. temperatures plummeted to as low as minus 12 celsius in scotland. the ploughs were out, shovelling industrial quantities of snow on the m90 motorway near dunfermline, though it wasn't enough to keep all drivers on the road. in towns and villages nearby, the spades were out to clear the way. she's just come in for a packet of cigarettes, and she's decided to clear my front path away, and that's community spirit for you. people have been helping

pushing cars up the street. heavy snow also fell in the north of england, where a hundred gritters were sent out onto the road network to keep traffic moving. motorways remained free—flowing, but other trans—pennine routes were closed. the flow has been falling steadily all morning across swathes of northern england — as predicted. it's been settling most in areas like this, just outside huddersfield, up here on the higher ground. in cumbria, hazardous conditions left some vehicles stranded on the a590, and there were also delays on other main roads. staff at the highways england control room in wakefield have been monitoring the motorways and a—roads. the next thing we're looking towards is the threat of ice for this evening and overnight, we've got teams of gritters working 21w, traffic officers patrolling the network as well, and obviously a team here in yorkshire and the north east working from the control room

to make sure that that impact‘s not too severe. drivers are advised only to travel if necessary, but traffic is lighter than usual, with schools closed and many off work for the holidays. enjoying extra opportunity for snow—themed entertainment. judith moritz, bbc news, wakefield. our correspondent lisa summers is in edinburgh for us now. describe how conditions have been where you are. well, the worst of the snow has now passed, but the worry overnight is going to be icy conditions, with temperatures dropping rapidly, even here in the city. looking further head, obviously we've got someone in is of heavy rain in the south of england, but here in scotland the concern will be about high winds. we have a warning in place for hogmanay, and edinburgh isa warning in place for hogmanay, and edinburgh is a pretty busy place at this time of year, 150,000 people aren't you to participate in a

three—day hogmanay festival that sta rts three—day hogmanay festival that starts tomorrow, things like a torchlight procession, a street party, a nine minute firework display, everything that depends on it not being too windy. so organisers will have a keen eye on the weather forecast over the next couple of days. i have been told they are expecting the wins to die down during the course of hogmanay, so down during the course of hogmanay, so hopefully we can enjoy new year without too much trouble from the weather. indeed, lisa, many thanks, lisa summers there. anti—government protests have spread to more cities in iran, despite a crackdown by the authorities. thousands of people have taken to the streets to protest over rising prices, corruption, and the cost of iran's military involvement in regional conflicts. wyre davies reports. these are extremely rare sights. cities across iran hit by large and sometimes violent anti—government protests. this is the western city of kermanshah, and despite the repressive action

taken against demonstrators by police, the protests have quickly grown, and spread across the country. iranians have suffered tremendous hardship, with a huge fall in living standards. but what started as a protest against rising prices has grown into much wider anger against strict clerical rule and iran's supreme leader snoke, ayatollah ali khamenei. demonstrators demand in that political prisoners should be freed and the government should stop spending millions on foreign wars. there is seething discontent with iranian spending money on wars abroad, on supporting hezbollah abroad, on supporting hezbollah abroad, and that has changed the character of the demonstration into a political one, undermining the whole clerical regime. iran's relatively moderate president

has, the benefits of economic growth, after an international deal to limit its nuclear activities, but those promises have so far failed to materialise. britain will be watching developments closely. 0n materialise. britain will be watching developments closely. on a recent visit, the foreign secretary, borisjohnson, raised the detention of the british woman nazanin zaghari—ratcliffe, held in an iranianjailfor zaghari—ratcliffe, held in an iranian jail for more than 600 zaghari—ratcliffe, held in an iranianjailfor more than 600 days. it's become a serious issue between london and tehran. it's too early to say if the regime is under serious threat. these are the biggest protests in iran for almost a decade and the government will use greater force if it feels it's losing control. wyre davies, bbc news. a huge fire at an office and restaurant complex in the indian city of mumbai has killed at least 1a people, including young women attending a birthday party. the blaze erupted just after midnight in the popular kamala mills compound and engulfed

the building injust half an hour. sanjoy majumder reports. the fire broke out on a rooftop restaurant in a popular commercial district in the heart of mumbai. within minutes, it spread — first to a bar next door, and then through the entire building. most of the victims were women attending a party at the bar. the bbc‘s gujarati service editor, ankurjain, was at the restaurant when the fire broke out. there was a stampede, and everybody was trying to just rush out. in less than three minutes after the fire started, the whole of the area was engulfed in fire, and before anyone, including us, could reach the staircase, the first place to catch complete fire completely was the fire exit. the blaze was eventually put out early in the morning — the structure completely gutted.

the families and friends of the victims are distraught and raising questions about safety measures. the building was located in a congested neighbourhood that once housed the city's colonial—era textile mills and is now filled with bars, restaurants and offices, some still located in the old factories, others in high—rise glass and steel towers. but many of them lack proper safety standards and emergency exits. an investigation has now been ordered to determine the cause. action has been taken against the restaurant owners, and five city officials have been suspended for negligence. sanjoy majumder, bbc news, delhi. the new york fire department says the blaze that killed 12 people, including four children, in the bronx area of the city appears to have been caused by a child playing with a stove. investigators believe an unattended three—year—old boy accidentally started the blaze, described as the deadliest in the city for at least 25 years. researchers in scotland

who saved the leg of a dog using a new technique to grow bones in a laboratory say they now hope to try it on human beings. the dog, eva, would have had her leg amputated, had it not been for this pioneering treatment. the team at glasgow university say the first human trials are due to take place in three years' time. 0ur science correspondent pallab ghosh has this exclusive report. eva! there's no holding her back, but last year eva's front right leg was broken in a road accident. her vet tried everything, but nothing worked. her entire leg was going to be amputated. well, nine, ten months, she'd been unable to get out and have walks, anything other than go out to the toilet. but to fiona kirkland's delight, her dog was saved by an experimental bone—growing technique. it's absolutely fantastic.

we're just so pleased to have our dog back, fit, active, healthy. eva's vet showed me the problem. the blood supply to the edges of the bones has failed, so it wasn't able to heal the break. the scientists coated the dead areas with their artificial bone, and afterjust six weeks, it was completely mended. the artificial bone mix was made at glasgow university. it consists of sterilised chips that are coated with bone cells and a chemical that make them grow, rather like a fertiliser. well, clearly, we want to look at treating more dogs and possibly even cats who have had broken bones, but also other areas we can help these veterinary patients, so things like joint fusion, where they've had a tendon injury and they need theirjoint held together so they can walk properly. the researchers are so amazed at the success they've had in treating eva they want to try out the technique on people. they plan to be the first

researchers in the world to grow bone in their lab and put it into a patient in three years' time. and these are the people that could be most helped. it's 20 years since princess diana brought the issue of landmine victims to the world's attention. their limbs usually have to be amputated. landmine campaigners are funding the new research so it can be used to grow some of their bone back and attach an artificial leg. well, if they are able to have a prosthetic limb, it would make all the difference to their life, being able to provide for their family, instead of having to be a burden on their family. it's been a happy outcome for eva and her owners. thousands of people could soon benefit from a technology that has put a spring back in her step. pallab ghosh, bbc news, glasgow. the labour peer lord adonis has

stepped down from his role advising the government on major infrastructure projects. in a resignation letter seen by two newspapers, the former transport secretary criticised theresa may's approach to brexit and claimed that she has become the "voice of ukip" within the conservative party. in the city, the 100—share index has finished trading for the year on a record closing high. it ended the day up 7.6% on last year. joe lynam is with me. why has this happened, and what does it signify? well, i think what this shows, reeta, is the disconnect between the real uk economy and these giant uk, needs that may be listed on the london stock exchange but the vast majority of their profits are earned overseas, and overseas is undergoing a boom. the united states, the far east, even the eurozone is having pretty robust growth, so it means that companies that are here can

sell more goods overseas, and a knitting a stronger currency because the pound is that little bit weaker, so they repatriate the property and stronger currencies and that boost their profits. the ftse 100 stronger currencies and that boost their profits. the ftse100 is not a great benchmark for the health of the uk economy, but a pretty good yardstick for the health of the global economy. joe, thank you. the nhs in england is considering the routine use of so—called drunk tanks — dedicated units for people to recover from excess alcohol — in order to reduce hospital admissions. up to 70% of visits to a&e departments on friday and saturday nights are by people who've drunk too much. adina campbell reports. at this time of year, britain's binge thinking culture is exposed with its burden on emergency

services. but having more of these mobile vehicles, or drunk tanks, on a permanent basis could be a solution — an idea now being considered by nhs england. alcohol result —— our coal recovery services are potentially successful in reducing pressure on a&e services, which is potentially important in winter. and so if there are ways that we can safely look after people in alternative settings, then it's really worth looking at these alternatives, and that's what we're doing at the moment. the reality is people who've overindulged with alcohol can be a big problem for the nhs. up to 70% of attendances to a&e departments in the uk at this time of year are alcohol—related. these friends are enjoying their annual festive get—together are divided. i think it's a good idea. i mean, if it helps the nhs and all that. but the thing that annoys me a bit is it seems to be our generation is being targeted. it also costs money. i don't think sitting down

in the van with a bottle of water is going to sober you up that quickly. if you are in that sort of a state, you want to either go home or go to hospital. the uk's first drunk tank was introduced in bristol three years ago, and since then more have been operating in cardiff, newcastle, manchester and belfast. rather than dumping those who have gone way over their limit in a police cell or hospital bed, here they're given a chance to recover. but some doctors say this kind of safety net shouldn't have to be offered in the first place. i think the solution is people understanding that they should not be getting themselves into the state that they need to have a facility to sober up in. people need to take responsibility for getting themselves home safely, making sure that their friends get home safely, that they have a plan