this is the briefing. i'm tim willcox. our top story: senatorjohn mccain's body arrives at andrews air force base in maryland. he'll now lie in state at the us congress before being laid to rest. after two days of violence, more far—right protests stoke fears in eastern germany. migrants say racism is on the rise. and new hope for children with a severe muscle wasting condition. researchers discover that gene editing will correct it in dogs. in business, he called it the worst deal in history. now president trump is closing in on a new north america free trade agreement, as talks with canada approach a deadline today. also coming up in the business briefing. desperate measures. argentina says it will talk to the imf on monday, after it raises interest rates to 60%, only to see the peso plunge further. a warm welcome to the programme.

briefing you on all you need to know in global news, business and sport. and you can be part of the conversation. tell us what you think, just use the hashtag #bbcthebriefing. the casket carrying the late senator john mccain has arrived in washington where he will lie in state ahead of a funeral service at washington's national cathedral on saturday. former presidents george w bush and barack obama, each of whom defeated mccain in their races for the white house, will offer their tributes. earlierfamily, friends and political rivals held a memorial service in arizona, as chris buckler reports.

people lined the streets in arizona to pay tribute to a senator who represented the state for more than three decades. # amazing grace...# as his grieving family watched, an honour guard carried john mccain into the baptist church where his funeral began with a much—loved traditional hymn. # that saved a wretch like me...# members of the public, arizona dignitaries and nationalfigures from both political parties were there. the speakers were eclectic, showing john mccain's extraordinary life. i'm black, he was white. a star arizona football player

reflected on the bond he had with his senator. he didn'tjudge individuals based on the colour of their skin, their gender, their backgrounds, their political affiliations or their bank accounts. he valued them on the merits of their character and the contents of their hearts. navajo musicians paid their own tribute that, john mccain himself ahd planned. my name's joe biden. i'm a democrat. and i lovejohn mccain. and for this former vice president and political opponent, his mattered more than their differences. —— his character. john's story is the american story. not hyperbole. it sounds like it. it's the american story. grounded in respect and decency. basic fairness. the intolerance for the abuse of power. # and now the end is near...# but this was not the end of the

tributes. from arizona, john mccain's body was flown to washington, a trip he made countless times through his lifetime. he has been given the rarer honour of having his body lie in state at the us capitol, out of a service at the washing machine shall —— washington national cathedral later this month. donald trump is not in invited to. precedence iraq obama, and george w bush will give eulogies. a sign that he crossed the political divide often to game respect of others. around 2,000 far—right, anti—immigra nt protestors have demonstrated in the city of chemnitz in eastern germany, for the third time this week. tensions have been raised by the killing of a german man early on sunday, blamed on an iraqi and a syrian

immigrant, who are now in custody. the bbc‘sjenny hill reports. it is not what angela merkel wanted. extremists on the streets, nazi slogans in the air. "lugenpresse", they shout — lying press. this city is caught between grief and anger. this is where a german man was fatally stabbed by, it is believed, by a syrian and an iraqi man in a street fight at the weekend. even the police admit they have been overwhelmed by the subsequent violence. it has horrified germany, terrified chemnitz‘s migrant population. abdul told us he was attacked on sunday. translation: a group of 15 men abused us, then beat us. i ran, but one punched me in the stomach. i fell and he took his foot

and stepped on the side of my face. and mara told us she locked herself and her children in theirflat for two days, too afraid, she said, to leave. but she is frightened too. "go down to town", she says, "see what happens to you as a woman!" there is only one person here speaking up for migrants. "open your eyes, wake up", they tell her. tense times then, for this troubled city. local politicians tonight appealed for calm, but few here trust them to keep chemnitz safe. angela merkel wanted to put the migrant crisis behind her. chemnitz may not let her. let's brief you on some

of the other stories making the news. astronauts onboard the international space station are having to deal with a leak most likely caused by a collision with a fragment from a meteorite. one of the astronauts, germany's alexander gerst, plugged the hole temporarily with his finger, before it could be covered with thermal sealant and tape. engineers on the ground are now working on a more durable repair, but they say the crew is in no real danger. american scientists say insects are likely to damage more food crops, as temperatures rise. their research suggests that in a hotter world, the metabolism of insects would increase, leading them to eat and breed more. cooler regions could be the worst affected, with maize and wheat yields falling significantly. worldwide, about two hundred million tonnes of grain a year are expected to be lost to pests. at least four people have been killed in a collision betweeen

a bus and a truck on a freeway in new mexico, according to local police. around 50 people were on the bus, travelling from st louis to los angeles. let's turn to our top business story. talks have continued into the night between the us and canada over the reform of nafta, the north american free trade agreement, ahead of a deadline today. president trump famously called nafta ‘the worst trade deal in the history of our country', blaming it for the loss of millions of usjobs, and made renegotiating it a campaign pledge. earlier this week he made good on part of that by striking a new deal with the other member, mexico. priya lakhani is the chief executive of century tech. lovely to see you. so, the worst

trade deal at the. he seems to have pulled a blinder on this one because he has done the bilateral with mexico and canada is scrambling to get on—board. mexico and canada is scrambling to get on-board. i wondered if that had decided to do with his relationship with justin trudeau. decided to do with his relationship withjustin trudeau. this is unusual, they raised a tequila over it and now canada has until the end of today to try and join this agreement to. there is lots of negotiation going on about the chapter 19 dispute resolution in the old nafta and obviously canada is try to protect its dairy farmers because in nafta there is up to 300% of tariffs. said the us wants to reduce those. it is milk on the dairy products. unfiltered milk has been blocked in the past from the us going into canada. the us and canada are they try to protect their own farmers. this is donald trump's whole america first policy, but this is not the first agreement that he

has threatened to pull out of. that seems to be a trend. i will pull out, sit at the table and re— negotiate. will come to the wto in a moment. in terms of nafta, he has one in terms of wages for car workers. $16 and hour is the minimum for a certain percentage. this benefits the us and canada in terms of raising those wages. is also about taking trade away from china and taking elements of car manufacturing and buying parts from china. i think a lot of this is shifting because of donald trump's policies with china. there are certain things that obviously and that canada and the us. just briefly, wto. in an interview with bloomberg, trump describing and other trade deal as the worst deal ever. the wto was obviously established to provide global trade

dispute relief. they have money that they want it had potentially impose against china, china has been lodging complaints, retaliating but have filed complaints. trump complains that they lose much all of the cases and are treated unfairly. actually, the usa have one more than 90% of the cases that they have initiated, but have also lost 90% that other members have wrought in. they bring in more cases than any other members of existing complaining about the specific. other members of existing complaining about the specificli forgot that they were only created in 1994. and led by the us. this is him saying, paris climate change, nafta, i want to walk away, bring the members back together to renegotiate. thank you very much indeed. you are watching the briefing. scientists in london and texas believe they've made a significant step towards an effective treatment for the fatal muscle—wasting disorder, duchenne muscular dystrophy. using the technique known as gene

editing, researchers found they could correct the dna of a small group of dogs with the condition. this from our medical correspondent fergus walsh. part beagle, part king charles spaniel, these young dogs all have duchenne muscular dystrophy. the condition mostly affects males in both dogs and humans, and it gets progressively worse as they age. now look at the contrast with these females, who carry the faulty gene but are unaffected. the dogs are part of a groundbreaking project published in the journal science involving the royal veterinary college and the university of texas. this research involved editing the dogs‘ genome, the recipe book for life. a faulty gene in the dna causes their disease, duchenne muscular dystrophy. the gene editing system known

as crispr was injected into the dogs. it scans the genome, making a single cut at a precise point. this prompted a natural repair and enabled the dogs to produce the dystophin protein which is crucial for muscle strength. these dogs normally do not produce any dystophin protein or effectively no dystophin protein. and by modifying the dna in their muscle cells and their heart we have gone from effectively zero, to up to 92% levels of protein, and that is widely predicted to be life—changing in human beings if we can get to that amount. you have to press that. and that really could be life—changing for felix. he's six and his muscles are already beginning to weaken. early treatment is vital for him because time is running out. the prognosis for the duchenne kids is very, very bad. they deteriorate very quickly from the age of sort of seven and eight, and normally lose

the ability to walk by the time they are 10, 11, 12. and then it's a very rapid decline from then. we trade in hope. so, you know, to hear about something like this is absolutely fantastic. these animals are all descended from one dog, whose owners brought it to the vet with the muscle wasting condition. and scientists found it had the same gene defect as in humans. these dogs are playing a key role in the search for an effective treatment for duchenne muscular dystrophy. a devastating illness. but longer term studies are needed to show whether it actually improves muscle strength and is safe. only then would it be tested on humans. it is early days, but this research could ultimately benefit both humans and dogs, affected by one of the most severe of all genetic conditions. stay with us on bbc news.

she received the nobel peace prize for her work with the poor and the dying in india's slums. the head of the catholic church said mother teresa was a wonderful example of how to help people in need. we have to identify the bodies then arrange the coffins and take them back home. parents are waiting and wives are waiting, so... hostages appeared, some carried, some running, trying to escape the nightmare behind them. britain lost princess today, described by all to whom she reached out as irreplaceable. an early—morning car crash in a paris underpass ended a life with more than its share of pain

and courage, warmth and compassion. you're watching the briefing. 0ur headlines: there's been another anti—immigrant protest in the city of chemnitz in eastern germany, after the killing of a german citizen on sunday. senatorjohn mccain's body has arrived at andrews air force base in maryland. he's set to lie in state in washington, before being laid to rest. brazil the resident is now saying it would be unthinkable to close the border to venezuelans fleeing economic turmoil. —— president.

michel temer has said little might start limiting the number of venezuelans start limiting the number of venezuela ns allowed start limiting the number of venezuelans allowed in. the venezuelans allowed in. the venezuelan exodus is threatening to over one neighbouring states. this was not what they had hoped for when they left the chaos of venezuela looking for a better life. sleeping rough on the streets of brazil's border strait of roraima, it's thought that hundreds of venezuelan migrants arrive here every day. the mayor's office says around 3,000 are now homeless. translation: i came to get ahead, to get a job and take things back for my children. but all i have now is exhaustion from sleeping outdoors. the influx of people has strained resources and cause conflicts between locals and newcomers. earlier this month, a migrant camp was attacked and set on fire. and yet the people still continue to come. on tuesday, soldiers were deployed to the state to re—establish law and order. brazil's president, michel temer, says it is for the safety and security of brazilians and venezuela ns alike, but he later caused

concern when he suggested brazil might cap the numbers allowed in to between 100 and 200 each day. on thursday he clarified, saying the border would remain open. translation: it would be, i repeat, unthinkable to close the borders. i do not understand how people could say that president temer now wants to close the borders. it will not happen, this will not happen. and still, the economic meltdown in venezuela continues unabated, with electricity blackouts, food shortages, and hyperinflation. venezuela's government says the situation is the work of foreign enemies, but one thing is clear. what started as a crisis in just one country is now fast becoming one for an entire region. phil mercer is in sydney and joins us how. phil mercer is in sydney and joins us now. so, the catholic church says this relationship is akin to a sort of client— lawyer relationship? that's right. the church says it has

no intention of changing the rules of secrecy surrounding the confessional. the catholic bishops conference here in australia says it is one of the main tenets of their faith and that to change it would go against everything they believe in. you have to say there could well be a collision looming between the catholic authorities. this is the biggest religious faith here in australia, and the state and federal authorities, given that two australian states have made it a crime for priests who failed to report child abuse that they hear on the confessional is. on the one hand you have the authorities who say that priests must give up this information, and on the other hand you have the catholic church saying, no, these secrecy rules are the fundamentals of our fate. what is the church's argument? that this would undermine the confidence and faith people have in terms of their confession? 0r faith people have in terms of their confession? or what? well, one of

the catholic bishops speaking here in sydney a few hours ago was saying there is a plaque will side of this, he said most confessions are anonymous, and if somebody came into the confessional booth and described being the victim while perpetrator of the abuse the priest listening to that would have no idea who that person was talking about. so from the catholic should's point of view there is a practical side of this, and also there is a religious side to this as well. the catholic bishops saying that it is a fundamental part of their religious freedom to have the secrecy in place. they have offered certain conditions around celibacy of priests, perhaps changing that, and also making child abuse not covered under canonised wall, but those changes probably won't help all convinced the governments here in

australia that no more change is needed. confrontation here between the church and the state and federal governments seems likely. you're watching the briefing. now it is time to all the latest sports news. hello, i'm chetan pathak. coming up on your friday sport briefing, the greatest sister act of all time takes centre stage at the us open. bolt swaps spikes for studs and vettel comes a cropper in milan. serena meets her big sister venus williams in the third round of the us open on friday. it'll be the 30th contest between the two. serena, looking to win a record equalling 24th grand slam title, currently leads the head to head 17—12. friday could be the day we see one of the great olympic athletes of modern times playing a completely different sport, because usain bolt is tipped to make his football debut in australia later.

bolt‘s been training with the central coast mariners, who play in australia's top flight, as he looks to persuade them to give him a professional contract. the side play a pre—season match in the next few hours, with bolt expected to play the last 20 minutes or so. around 10,000 fans are expected to watch. roger federer‘s run for a sixth us open title continues after he beat france's benoit paire to book his place in the third round at flushing meadows. federer struggled with his serve at times but came through 7—5, 6—4, 6—4 and faces australia's nick kyrigios next. it is always tricky against ben wyatt pair because they think against one another, there is a lot of tactics going on. —— benoit

paire. sometimes he will play deep in the court, then up in the court. that is maybe why you draw errors out of each other, and then the match maybe doesn't look as good. plus, he covers the court to very well. so sometimes you have a tendency to over players well. at overall, i'm happy. in the women's singles, angelique kerber was among the early winners on day 4. the numberfour seed is bidding to win back—to—back majors following her victory at wimbledon, but she was made to work hard for her win overjohanna larsson. kerber took the first set 6—2, but the swede, who's ranked 82 in the world, levelled by taking the second set 7—5. in a match punctuated by long rallies, kerber, who won the us open title two years ago, took the deciding set 6—4 to seal her place in the third round. the queen of soul, aretha franklin, will be laid to rest in her beloved hometown of detroit later today following her death two weeks ago.

the funeral service will be a private affair following a huge tribute concert which finished in the last hour. tickets for that event went in just six minutes as thousands gathered to pay their last respects to a musical legend. so we will end the programme with a snippet of that concert, and the song synonmous with her, respect. # what you want baby # i got it what you need # do you know i got it? # all i'm askin' is for a little respect # r—e—s—p—e—c—t .just part of . just part of a tribute concert to

aretha franklin. we will be back in a few minutes with the business briefing. and we will have more on what you think about the talking points about president trump's decision to talk about the wto, now threatening the wto, the world trade 0rganization, saying it was the worst deal everfor the 0rganization, saying it was the worst deal ever for the country, that comes after the renegotiation of nafta. see you soon. hello. let's get a check on the weather front. technically speaking, friday marks the last day of summer. according to meteorologists, it technically becomes autumn. in the short term there is a bit of cloud to the west of us that will bring a few spots of rain, possibly to some western areas in the short term. as far as the night is concerned, the

end of the night and into the morning, it will be pretty nippy first thing in the morning. immigrants of scotland and parts of northern england it may only be a few degrees above freezing, but that is way out of town. this is what it looks like during the course of friday morning. lots of sunshine across the country and through the course of the morning and into the afternoon, clouds will be building up afternoon, clouds will be building up in some areas. just the risk of a shower in the south—east. in london, and even in the lowlands of scotland, temperatures will be around 20 or so. a weather front will be approaching the uk during the course of friday and two saturday. so there is a chance of a little bit of rain. across some western and north—western areas. but it won't be an awful lot. we are talking about a few spots around the irish sea and maybe western parts of scotland, and to the east and south it is going to be dry. 0n scotland, and to the east and south it is going to be dry. on saturday, a really present day on the way. temperatures will rise a little bit to about 22 degrees in london. maybe 22 in yorkshire as well. in the

lowla nds 22 in yorkshire as well. in the lowlands of scotland, a shade cooler, 18 degrees or so. on saturday and his sunday, we will see warmeraircoming saturday and his sunday, we will see warmer air coming out of the southern parts of france, and with high pressure very close by to the uk, it does mean that the weather is going to be settled. so the high pressure is here and the low pressure is here and the low pressure is here and the low pressure is just behind pressure is here and the low pressure isjust behind me there, would that weather front. the weather front cannot march in because this high pressure system is stopping it from progressing any further towards us. i think it. somewhere around western areas of the uk and the winds will be pretty light as well. so with sunshine and is light winds it is actually going to feel pleasant. as we go through the course of sunday and the rest of the course of sunday and the rest of the weekend it is just going to be warming up and up and up. by the time we get to sunday, temperatures could get to 25 degrees, 24 or 25, in the south—east, i think. not to bad this time of year. this is the business briefing. i'm tim willcox. he called it the worst deal in history. now president trump is closing in on a new north america free trade agreement — as talks with canada approach a deadline today.

plus — desperate measures. argentina says it will talk to the imf on monday, after it raises interest rates to 60% — only to see the peso plunge further. and on the markets, investors are rattled as president trump tells bloomberg news he could step up the trade war on china next week,