theresa may comes out fighting and tells eu leaders — if you don't like my brexit plan, where's yours? in a defiant and strongly—worded speech, she attacks eu leaders for being dismissive of the uk. i have treated the eu with nothing but respect. the uk expects the same. the eu has responded that it does respect britain's decision to leave the eu, and that a compromise which works for everyone is still possible. also tonight... two drugs companies lose their legal bid to stop the nhs using a cheaper medicine for a common eye condition. at least 131 people have drowned after a packed ferry capsized on lake victoria in tanzania. the messaging app used by paedophiles — how police are struggling to prevent grooming. and anthony joshua prepares for the fight which could cost him all his three world titles in one go. and coming up on sportsday on bbc news... englishman ollie fisher lands a moment of golfing

history in portugal — the first round of under 60 on the european tour. good evening. the prime minister has come out of her cornerfighting, after eu leaders comprehensively rejected her brexit plan yesterday. in a defiant speech, she has told them it's time to start treating the uk with some respect, and that it's "not acceptable" at this "late stage of negotiations" for eu leaders to reject her plan with no alternative. the two main stumbling blocks remain trade and the border with northern ireland. the eu council president donald tusk has responded this evening — saying that mrs may has known for weeks and in detail what the eu thinks of her plan — but that a compromise is still possible. our deputy political editor

john pienaar reports. theresa may's in a hurry, some say getting nowhere fast landing a brexit deal. so, how to come back from her diplomatic battering — the chorus of eu leaders telling her her brexit plan wouldn't fly. her answer in downing street? defiance — their turn to compromise. britain had rejected the eu's basic demands. uncontrolled immigration from the eu would continue. and we couldn't do trade deals we want with other countries. that would make a mockery of the referendum we had two years ago. she was prime minister of great britain and northern ireland. on no customs border with ireland or on the mainland, there would be no backing down. it is something i will never agree to. indeed, in myjudgement, it is something no british prime minister would ever agree to. if the eu believe i will, they are making a fundamental mistake.

mrs may was prepared to walk away from negotiations, though eu citizens settled here would have rights guaranteed. but after the headlines reporting the prime minister's rejection and humiliation, she came back with her own final demand. throughout this process, i have treated the eu with nothing but respect. the uk expects the same. a good relationship at the end of this process depends on it. european leaders lined up against her this week. now she was keen to show she'd face them down. but there are potential dangers behind her, at home. brexiteer tories demanding no compromise. they are campaigning to adopt the so—called chequers plan, which leaves the uk tied to some eu rules and standards. —— they are complaining took dump the so—called chequers plan. it was making it apparent that no

deal remains better than a bad deal, and that she is not going to give in to the bullying by the european union, and that's very important. however, it's a mistake to persevere with chequers — that's not really brexit. the eu doesn't like it because it leaves us too tied in to their rules but without respecting their institutions. from my point of view and from the brexiteers' point of view, it isn't properly leaving the european union. the irish border and how to avoid border checks after brexit is still a barrier to a deal. british proposals need more work and more negotiation, the eu council president donald tusk said in a statement tonight. he also called britain's brexit position this week surprisingly tough and uncompromising, though he shared the view of ireland's leader that agreement was still possible. i think we can have a deal, we're entering into a rocky patch over the next couple of weeks, but i'm determined to keep working and secure the deal that we need. in parliament they say your enemies are behind you, but here, mrs may's labour opponents are also preparing to defeat any deal she comes up with. their wish list — an early election, maybe another referendum.

to them, every bad day for mrs may is an opportunity to make it worse if they can. the prime minister's negotiating strategy is collapsing around her, and now the country is staring down the barrel of no deal. the prime minister's chequers proposal was never going to be accepted either in the eu or by her own party, and so she's in denial. the prime minister's back on her berkshire constituency. it won't count as an escape. she couldn't get away from her troubles over brexit if she tried. john pienaar, bbc news, westminster. we'll talk to john in a moment in downing street, but first our europe editor katya adler is in munich this evening. the president of the eu council, donald tusk, has responded to the prime minister's speech in a statement this evening. what did he say? well, the whole statement came across as partly

defiant and defensive, and partly just wanting to be friends again with theresa may. donald tusk is far from the only eu leader to be really taken aback at how the salzburg is it was interpreted in the uk. they say they are absolutely did not go out to ambush the prime minister or to humiliate her, but donald tusk was the only eu leader to be name checked by theresa may in her brexit statement this afternoon. as the president of the european council, the representative of all eu countries who publicly dismissed key parts of her chequers brexit proposal as unworkable. now, parts of her chequers brexit proposalas unworkable. now, he parts of her chequers brexit proposal as unworkable. now, he said in his statement he was simply matching strident tone for strident tone, he described theresa may as surprisingly tough and uncompromising at the salzburg summit. but it is clear now that both of them misjudged the mood and the political sensitivities of the other. there haven't been any other official reactions from eu leaders

to theresa may's statement this afternoon. they basically see it is directed more at a domestic audience and trying to bolster her political position at home, but eu leaders wa nt position at home, but eu leaders want a deal and donald tusk said in his statement he still thinks a compromise deal, good for both sides, is possible, and he's signed off isa sides, is possible, and he's signed off is a close friend of the uk and a true admirer of theresa may. i couldn't help but wondering, what herfacial couldn't help but wondering, what her facial expression might have been as she read that this evening. we will never know! john pienaar in downing street, the prime minister, it was a very bruising day yesterday for the prime minister. today, she's determined to show she's down but not out. what was your assessment of what she was trying to achieve in her speech? theresa may's defiant today clearly was meant to tie in with the feeling of brexiteers in her party at a very crucial stage. it was also an assertion of authority and of credibility after a painfully difficult eu summit and the even more difficult that will

stop she does get some credit, some respect, for the way that she soldiers on against the odds but i don't think that ultimately cuts that much ice with the brexiteers, who want her to drop the brexit compromises that have already cost her two cabinet ministers and could conceivably cost more in the future. we are expecting more british proposals on the irish border now but they'd have to be something quite unforeseen to successfully break that deadlock, without upsetting the democratic unionist party m ps upsetting the democratic unionist party mps theresa may and relies on for her majority in parliament. where does this lead her? in a tight corner with no root real political wriggle room, no deal in sight, with time running out and no clear majority in parliament for any outcome. no one can rule out some kind of agreement in the time that remains, but equally i think no one can be truly confident of that happening, listening to theresa may's defiant, unyielding tone today, the way that was echoed from brussels, and knowing as i think we

surely do that there will be more of the same from theresa may when she goes to what will be for her difficult annual party conference in just over a week's time. john pienaar in downing street, thank you. two major drugs companies have failed in an attempt to prevent nhs doctors prescribing a cheaper treatment for a serious eye condition, in a ruling that could save the nhs "hundreds of millions" a year. avastin is just as effective as the two more expensive treatments for wet age—related macular degeneration — a common eye condition which can lead to sight loss — but the drug isn't licensed to be used for it here in the uk, as dominic hughes reports. come and have a seat on the chair here, stanley. for more than three years, stan nelson has been treated at sunderland's specialist eye hospital for what's known as wet age—related macular degeneration. it's a condition that can lead to rapid sight loss. just checking that it's the right eye that we're doing. a drug is injected into stan's eye. a little bit of pressure. helping to save his vision and preserve the independence of this 87—year—old. at the moment, patients like stan are offered one of two possible

treatments to help with this debilitating eye condition, wet amd, that affects around 26,000 people in the uk. but at the heart of today's legal case is the right for doctors to offer a third option, avastin — a cancer drug that is just as effective, but is much cheaper. after receiving his treatment, stan told me he'd be happy to have the cheaper avastin. i can't have any objection to it at all, really. as long as it works, as long as it does the same job or better, that's fair enough. these are the two drugs currently licensed for treating the eye condition in the uk. lucentis costs £56! per injection. eylea costs even more, at £816. avastin, currently only licensed to treat cancer, is far cheaper, at £28. switching to avastin could save the nhs up to £500 million a year. when pharmaceutical companies are prepared to put their shareholders' profits

above absolutely anything else, then that does put us in a position of conflict that we didn't really want, but we've had to take on that challenge on behalf of our patients. 0k, look straight ahead...and blink. doctors are now likely to be looking at other treatments that could take the place of more expensive drugs. the two pharmaceutical companies involved in today's case, novartis and bayer, say this judgement marks a bad day for the nhs, undermining the regulations set up to protect patients, and they‘ re considering an appeal. dominic hughes, bbc news, sunderland. let's take a look at some of today's other news stories. a male model has beenjailed for at least 2a years for murdering a rival model in a row about a girlfriend. george koh stabbed harry uzoka outside his house in shepherd's bush in west london injanuary. a third man, who was convicted of manslaughter, will serve 11! years in prison. the coroner overseeing the inquests into the grenfell disaster has said people exposed to smoke and dust should be seen by nhs specialists. dr fiona wilcox warned that those

who survived the fire — including residents and emergency responders — may have inhaled asbestos, which causes cancer. nhs england says it will respond in the next couple of months. the metropolitan police have admitted for the first time that a sexual relationship between an undercover officer and an environmental activist was known about by senior officers and allowed to continue. until now the police had denied that such relationships would ever be authorised. a woman dubbed the "snapchat queen" has been jailed for 11! years for manslaughter, after posting a video of her boyfriend dying in a pool of blood on the social media platform. the old bailey heard fatima khan had grown tired of her boyfriend khalid safi — an afghan asylum seeker. she plotted with another man — raza khan — who carried out the knife attack in december 2016. he is still on the run. a bbc news investigation has found that police are struggling to combat

child grooming taking place on a smartphone messaging app called kik, which is popular with teenagers. kik has played a part in over 1100 police investigations into child sex offences over the past five years. but officers say the company won't help identify predators unless they overcome major bureaucratic hurdles. angus crawford reports. mark, you're wanted. not the wake—up call he was expecting. hello, are you all right? mark kirby is about to be arrested. under his duvet, two phones — from his bed, he's been sexually grooming children using kik, a messaging app — free to download and popular with teenagers. you're under arrest... he was sent to prison for more than three years, but kik‘s users are often anonymous, so police can't trace and help his victims without help from the company. there's a child that is probably going to be abused for another 12 months before we know who that is.

and kirby's case is not the only one. look — these diagrams show other offenders northampton police need to track down. so each one of these could be a predator? yes. abusing children? yes. but kik won't help unless officers start a formal international legal process, taking months and costing money the force doesn't have. so when you ask kik, you get an automated response? yes. so you, the police, get an automated response, saying we can't provide that information? yes. it's a bureaucratic nightmare. it was abuse, yeah, sexual abuse — the worst form of hurting a person, really, is hurting a child. vulnerable and lonely, taylor was first groomed on kik at the age of 13. it started in moments, but lasted years. it started with a lot of selfies, but then, yeah, it would escalate to underwear photos, like naked photos, and videos, yeah, bad — they ask you to perform sexual acts,

film them and send that. how many men do you think may have tried to groom you? over 100, possibly up to 200, yeah. that's shocking. yeah. and it's still rife. posing as a child, within seconds we get this message from a 42—year—old man. then this. and there's more. we also find sexualised images of children, and users offering to share them. our research found kik featured in more than 1100 police investigations into child sex offences across the uk in the last five years. kik refused our request

for an interview, but in a statement said, "we take online safety very seriously, and we're constantly assessing and improving our trust and safety measures. " it says it will continue to, "provide resources to parents and strengthen relationships with law enforcement and safety focused organisations." safety focused organisations — what do you think of that? i think if that was the case, i probably wouldn't be sitting here talking to you now, because there's clearly a problem. i've clearly got cases, as any other police officer, that we're banging our heads against a brick wall. leaving offenders at large and victims unprotected. it's all going on behind closed doors, but there you can see it, that they're not doing anything about it, because at the end of the day it makes them money. angus crawford, bbc news. at least 131 people have drowned after a packed ferry capsized on lake victoria in tanzania.

it was sailing between two islands when the accident happened. tanzania's president said negligence had contributed to the disaster. from nairobi in neighbouring kenya, anne soy reports. they stand and watch, helpless. just a few hundred meters away, the upturned hull of the mv nyerere. rescuers who arrived by boat recovered bodies from around the capsized vessel. back on shore, relatives waited anxiously for news. translation: i was told that i lost my aunt, my father and my younger sibling. it's a huge cost to us. translation: my nephew is on the island. he told me the news that his father, my brother, was on the ferry. it's unclear how many people were on board the mv nyerere. witnesses say it could be as many as 400, four times its official capacity. translation: when the captain was trying to slow down

and about to dock, the passengers were already running to the other side, ready to get off. so, now, the weight was too much on one side of the ferry. so, it capsized and sank. although accidents aren't uncommon on africa's biggest lake, this latest sinking was particularly deadly. the country's president said he was deeply saddened by what had happened and said several arrests had been made, including the captain, who apparently wasn't on board at the time of the sinking. anne soy, bbc news. the deal to avert an all—out battle in idlib in syria hangs now on the reaction of the 10,000 or so extremists, including foreign fighters, who are still fighting the assad regime there. on monday turkey and russia agreed to set up a demilitarised zone in the region to try to avoid further bloodshed. a deadline has been set for what russia insists are terrorists to leave idlib by the middle of next month.

but will they? the bbc has spoken exclusively to a group of british extremists in idlib who have lived and fought in syria for years. our middle east correspondent quentin sommerville reports from the turkey syria border. these are two of the last british armed jihadists still fighting in syria. they have allied themselves with some of the most notorious extremist groups. this is idlib and one of them is from brighton. he turned his back on britain for good five years ago. there is a relief in idlib that an onslaught has been averted. he's taking a break to go shopping. in britain, he's a wanted man. in syria, he is free. he came here to wage holy war, in the meantime got married and had a daughter.

i've been speaking to them via skype for months. no longer wanted back home in britain, they are increasingly unwelcome in syria too. you and your foreign islamists friends say that you went to syria to help? a lot of syrians would say you've only made things worse and it's time for you to go? nobody has asked me to leave or say that i've made it worse, to be honest with you. but it sounds like there aren't many options left and it sounds like the only options left for you and other foreign fighters are death or capture, is there a third option? if i believed what you said i would have been gone a long time ago. for me, in syria there is always changes, always obstacles, there's always difficulty. but the difference between me and you is i have belief. a fundamentalist belief is what still powers these men, even as they are losing the war.

but these men won't give up support for the al-qaeda linked hts nusra. abu yusuf says he'll never leave syria but he still wants his identity disguised. isn't it the case though that you and other foreign fighters should just reconcile with the regime, put down your weapons and leave? so if i lay down my weapons now, you know, what kind of insurance i have that the regime, they are not going to continue raping, killing and... of course there's no insurance. no superpower is going to come in to save the dayjust because i put my weapon down. you say even if we die here, we are happy. that's fine for you, that's your choice to make that sacrifice. but what about the civilians, what if you are sacrificing them? that's not their choice. if you can assure me that they are not going to be slaughtered and raped and oppressed, by me disappearing, you can't give me that assurance. here, they balance family

life and armed jihad. they have married syrian women, but still they don't truly belong. on the hills outside idlib, yet another british fighter is on patrol. some foreign fighters have cut their ties and fled syria in the last few weeks. others are secretly making preparations for their families. he says he's staying. these may be the last moments of what counts for ordinary life for british armed jihadists, but they have never been more isolated. their next move and that of their extremist allies, has never been more important. the fate of 3 million people trapped in idlib may depend on it. quentin somerville, bbc news. the ukip leader, gerard batten, has said the party plans to contest every seat at the next general election and that they'd be targeting remain—supporting mps. speaking at ukip's annual conference in birmingham,

he said he wanted the party to become more populist. britain's world heavyweight boxing champion anthonyjoshua admits he's facing a tough challenge from his latest opponent, russia's alexander povetkin. the two men weighed in today — ahead of their fight at wembley stadium. for the first time all three ofjoshua's world titles will be on the line. our sports correspondent david ornstein reports. anthonyjoshua... he's a man mountain of british sport. the biggest draw in global boxing about to pack a major stadium for the fourth time injust 17 months. with each anthonyjoshua fight, the anticipation grows and so too a feeling that the best may yet be to come. i still feel like i've got everything to gain. you know, there are stages that you think well, we've come this far and it's been great and you've enjoyed it, but at the same time you think, hang on a minute, imagine another

five years of this at staying on top of your game? so you still feel like you've got everything to gain so the pressure, 100%. but then again, you get used to it as well so it becomes the norm. this isjoshua's final public appearance before the bell rings tomorrow night. his three world titles on the line for the first time, even if this isn't the contest many wanted to see. his two main rivals are britain's tyson fury and deontay wilder of the usa. but for now, the focus is on alexander povetkin, a fellow olympic champion but with a chequered past, having twice committed doping offences. myjob in this issue is to show that a non—drug cheat is a stronger and better fighter. if they were so you know, concerned about drug cheats, then he wouldn't be in a position to fight me saturday night. cleared to compete, povetkin has nothing to lose. the onus, the expectation is onjoshua. david ornstein, bbc news, wembley. back to our top story and with the eu and the prime minister at stalemate over brexit, what are the different options now for the uk?

there are just six months left until we leave the eu and our deputy political editorjohn pienaar has been to paignton in devon to look at where we could go from here. how will trade work after brexit? will we be richer or poorer? why haven't we left yet? will it definitely happen? where's the brexitjourney leading? the leaver‘s slogan was about taking back control, so the promise is a return trip to the way things used to be, a more british way. whistle. but from here, britain's post brexit journey could take any number of directions. there is the spoke trade deal that theresa may wants, or a free trade agreement, maybe like the deal the eu has with canada. or talks could end with no deal at all. and the truth is, the prime minister can't know where we'll end up. her plan for a common rule book

for trading goods and a free—market in services goes against the eu system of a single market and brussels is saying no. it's too close to the eu for tory brexiteers like borisjohnson, who quit the cabinet right after david davis and others could go too. for former tory remainers, they'd like a closer relationship with the eu. the fact is, there is no majority in parliament for any outcome. just now, no one is sure where the country will be or where we will be heading when the uk ends the eu journey that started when britainjoined in 1973. it's maybe likely the prime minister's own future depends on reaching some destination, as the country stepping off the eu train on schedule, as she pledged on march the 29th, next year. could britain somehow walk away from the eu and put off the really big decisions about the future until after brexit day? kick the can down the road again, something that's possible. and britain's long brexitjourney

faces another big obstacle. thank you. thank you very much. on the island of ireland, all sides are committed to avoiding a hard irish border when the uk leaves. there is no agreement on how to do that. and there's no clear way to fudge that question just to keep brexit moving. in the end, there will be more big decisions to take at westminster by our politicians. the pm needs to win a vote here on any deal, if there is one in october, or likely later. lose it and anything could happen. mrs may might have to go, so an immediate tory battle for number ten. supporters of an eu referendum are hoping deadlock could lead to what they're calling people's vote and mrs may and brexiteers say would be a betrayal of democracy. the labour leader is not convinced it could ignite fury among brexit supporters and as for reversing brexit, the cries of betrayal would be deafening.

but some mps on both sides are hoping for even that. this row has the capacity to split the tory party and labour too. and who knows, deadlock and crisis could conceivably lead to an early general election. brexit is the biggest question facing britain since world war ii. if no clear way through is found, you might just end where it started — with the people. john pienaar, bbc news, westminster. you can find all of our pieces from this week looking at the key questions about brexit online. go to the bbc iplayer and click on news, then scroll down. that's it from us for this evening. now on bbc one, it's time for the news where you are. bye— bye. hello and welcome to sportsday, i'm steven wyeth. fisher lands golf‘s magic number as he goes sub—60 on the european tour. two new openers for england, rory burns gets a call—up for the test squad, along withjoe denly. weighing up the opposition. anthonyjoshua puts his belts

on the line as he takes on alexander povetkin. tough fight, everything is on the line, you want to become champions. u nfortu nately line, you want to become champions. unfortunately he has this beat me andi unfortunately he has this beat me and i have to defend it, i've got nothing to lose and everything to gain. hello and welcome to sportsday. certain numbers in sport motivate like no other. in snooker it's a 147 break. in running it was the four minute mile. and in golf it's the sub—60 round. until today that had been beyond reach on the european tour. many had come close, but until oli fisher signed his second round card at the portugal masters, none had written 59 as their total, more from ben croucher. just two feet from