tonight at ten, the government's legal advice on brexit is published in full, as the prime minister denies misleading mps. have you lost control of brexit, prime minister? mrs may was warned that measures to avoid a hard border on the island of ireland could last indefinitely, prompting claims that she hid this from mps. is it time that the prime minister took responsibility? responsibility for concealing the facts on her brexit deal from members of this house and the public. the legal position that was set out on monday in the 34—page document, together with the statement made and the answers to questions given by the attorney general on monday, very clearly set out the legal position. we'll have reaction to the legal advice, and we'll be considering the range of options open to the government if they lose the big brexit vote next week. also tonight. major improvements in medical treatments, after scientists complete a gene sequencing project. we'll have the details. we report on the damage caused by new synthetic drugs,

including monkey dust, and we talk to some of the victims. it's destroying your insides, it's a psychoactive drug that's destroying you mentally. and people know nothing about it. a bbc investigation has found that a student from bath set up an extreme neo—nazi group which urged attacks on public figures. and in washington, a state funeral for george bush snr, the former us president, with a family tribute from one of his successors. a great and noble man. the best father a son or daughter could have. and coming up on sportsday on bbc news, reaction from old trafford as manchester united host arsenal, who are unbeaten in 19. that's one of six premier league matches this evening. good evening.

the prime minister has been accused of misleading mps, following the publication of the government's full legal advice on brexit. the document, which ministers were forced to publish after a vote by mps yesterday, includes legal opinion on the so—called backstop. that's the guarantee of no checks on the irish border in the event of no trade deal between the uk and the eu. the attorney general, in his legal opinion, warns that despite the intention to make the backstop temporary, it could "endure indefinitely", and he warns that the uk could be involved in "protracted and repeating rounds of negotiations" with brussels. our first report is by our political editor laura kuenssberg. grimly carrying on.

after three defeats in parliament yesterday, now a legal mess, on the most contentious part of the brexit compromise, that so—called backstop. have you lost control of brexit, prime minister? after number ten was forced to publish its private lawyer's advice on how northern ireland would be more tangled up with the eu than the rest of the country. questions to the prime minister. we have seen the facts that the government tried to hide. mr speaker, this government is giving northern ireland permanent membership of the single market and the customs union. the prime minister has been misleading the house, inadvertently or otherwise. a serious charge to lay around here. the prime minister says there is nothing new. there is indeed no unilateral right to pull out of the backstop. what i have also said is that it is not the intention of either party that the backstop should be used in the first place or if it is used, to be anything

other than temporary. but there was more. those northern irish mps who were meant to be the prime minister's friends, sounding more and more like her enemies. does the prime minister agree that at this last moment that the entire premise of the backstop has been based on a false assertion? yet the legal advice spells out in more gory detail what the government had tried to gloss. the attorney general writes that the so—called backstop will apply differently in great britain to northern ireland, two parts of the uk with separate rules. and that the european courts will continue to have jurisdiction over northern ireland. the legal advice also states this relationship would endure indefinitely, until another agreement takes its place. that could take a long time. the advice makes clear though that neither side wants it to happen. it is not a comfortable resting place for the eu, either.

the prime minister is trying to persuade people to vote for her deal. what this document shows is the weaknesses of her deal, and she didn't want to tell people what they were. and remember, unhappiness over the backstop is what makes the overall backdrop for the government so gloomy. dozens of tories loudly swearing they will reject the brexit compromise because of it. well, it shows the very predatory nature of the eu's claim to northern ireland. it's very extraordinary that there will be a different relationship between northern ireland and the eu. is it realistic to imagine you can get rid of the backstop now? of course it's possible. it's not essential for the negotiations. is there any way you can see yourself voting for this as it stands?

no, there is no point in having a mishmash of remain and leave when the result is so bad. if its that bad, is there any point in leaving? let's throw the deal out. as for whether this deal is better than remain, i'd have to admit it's a pretty finely balanced question. it might feel like it but this is not a rerun of the referendum. in less than a week, mps will vote not on in or out, but on the prime minister's compromise, and there is a minority ready to grin and bear it. i think people should be thinking carefully before they vote it down because we would be in unprecedented territory and i think mps have got to rise to this occasion, step up to the plate and sort it out, to show we can do that without having to spend too many more months arguing about it. this could move fast but right now, there's no sign of enough support for the prime minister's plan. that's why in private, conversations are starting to swirl about the kind of extra promises theresa may may have to make to get

this done. but so far, there is nothing firm on the horizon that would really change the equation. after more than two years of argument, there is now an agreement. in less than a week, mps will give their verdict on it. but don't hold your breath for a sudden outbreak of goodwill. laura kuenssberg, bbc news, westminster. as the debate at westminster continues until the vote next tuesday, there are a number of uncertainties. will the prime minister's deal get through? could there eventually be a second referendum, or could the uk leave the eu with no deal at all? our deputy politcial editorjohn pienaar looks at what could happen next. despite all the setbacks and all the defeats, theresa may is battling on, standing by her plan for brexit, maybe against all the odds. but what happens next? let's say mrs may wins. that may look unlikelyjust now, but if parliament approves her plan, britain leaves on schedule on march 29th, an unexpected triumph for mrs may.

at this stage, it seems more probable that she loses. her conservative critics may then try, again, to force a vote of confidence in her and either way, labour will look at tabling a vote of confidence in the government. that would be hard to win. tories and the dup would have to vote for it. meanwhile, unless mrs may manages to somehow get a better deal in brussels, the uk would be on course to leave the eu with no deal at all. but the idea of what brexiteers sometimes called a "clean brexit" is just not that simple any more. mps voted yesterday to give themselves power to decide the country's next steps if mrs may is defeated, and there's no majority in parliament for a no—deal brexit. so, what then? there is support, within both main parties, for negotiating a new deal, outside the eu but close to it, a norway—style brexit, though brexiteers call that brexit in name only, "brino", taking eu rules

without shaping them, continuing free movement of people in and out of britain. in the end, could parliament simply fail to approve any solution and turn back to the people? a general election is one way and it's labour's first choice. it's hard to imagine, but even that can't be entirely ruled out. otherwise, the idea that seemed all but impossible until recently may be gaining ground among mps, as a potential way to break the deadlock. campaigners call it a people's vote. to most people, it's the idea of a fresh referendum. john pienaar, there. our political editor laura kuenssberg joins us. after this very perbet and 24—hour is, how do you read the options for the prime minister question but —— very turbulent 24—hour is. the prime minister question but —— very turbulent 24-hour is. the options are limited and at the centre of government, they are still trying, may be against hope but they are still trying to win the vote or reduce the numbers in what seems like a very likely defeat but of course there are conversations going

on about what might be the way out. a lot of suggestions today in westminster about a potential amendment, tweeting the legislation that mps have to vote on the straight. —— tweaking the legislation. but in terms of what might be acceptable or make a difference, there's nothing concrete on the table as i understand it and remember, brussels at this stage has no intention of reopening the deal so no intention of reopening the deal so if mps decide they can come around to something different, how would that fly with the eu? probably not at this stage. then there's the nuclear option, delaying the vote which is absolutely not something downing street wants to countenance right now. but it is something senior mps have been suggesting internally, saying, if you are heading for a massive defeat, for goodness' sake, stop that happening and then look at other options. but it is very hard to imagine that the prime minister at this stage will be open to that kind of idea. what you are open to that kind of idea. what you a re left open to that kind of idea. what you are left with is the prime minister's personnel ability to change minds, one by one. she's been

trying to do that in the last couple of days. she will be doing it again tomorrow, the next day and the next and the day after that but there are only six days until the vote and so far, it does not seem as though that process is going very well. one senior mp said to me today, "she doesn't listen to anyone so why should we listen to her?" at the same time, we may find over the course of the next week that the core of tory mps who just want to get on with this in the end grows and i'm not suggesting it is set for this vote to be some kind of victory but at least the scale of the defeat that some people talk about right now might narrow down for the prime minister, which gives her more options at least, the day after that. laura, many thanks again. laura kuenssberg, our political editor, with the latest on westminster‘s brexit story. turning to other news now. in a world first, british scientists have completed the largest gene sequencing project in health care. 85,000 people took part,

people with rare diseases, their family members, and patients with cancer. 100,000 genomes were mapped. the genome contains all a person's dna and is the blueprint for life. errors can trigger a vast range of disorders. many of those who took part in project have already benefited from a diagnosis or treatment for their condition. our medical correspondent fergus walsh reports. the faces behind the numbers. these are some of the people who volunteered to have their entire genetic codes sequenced, visiting the laboratories near cambridge where it was done. some are affected by cancer, others by rare diseases. sometimes, what we have to do is go back to the dna sample and do another library preparation... all are helping to improve our understanding of how genes influence our health from cradle to grave. inside nearly every one of our cells is a copy of our genome.

made up of 3 billion pairs of dna code and 20,000 genes, it is the instruction manual for how our bodies work. sequencing the first human genome took 13 years. now, a genome's worth of dna can be done in 30 minutes. that dramatic acceleration has enabled scientists here to sequence 100,000 genomes of people affected by rare diseases or cancer. every genome mapped by these machines yields vast amounts of data. so, how is that helping individuals and society? karen carter has contributed two genomes. first, the genes she was born with. then the dna from her breast tumour, containing the faulty genes that triggered her cancer. by comparing her dna with that of other cancer patients, it may explain why she and several

members of her family have developed cancer at a young age. knowledge is power and we need to find ways forward, because once you've had cancer, the worry is always there. good girl. mummy's turn. six—year—old tilly has a rare brain and muscle disorder that used to cause seizures, meant she lost the ability to walk, and made her aggressive around other children, like her brother arlo. it was not until tilly and mum hannah joined the 100,000 gemone project that scientists were able to compare their dna and finally found the cause of her condition, and an effective medicine. she has been treated now since march and the difference is amazing. her epilepsy is gone. she's developing every day, she's communicating. she's just full of life and she's not violent any more. she can be around her brother without attacking him. the 100,000 genomes project

is just the start. the ambition is to sequence a further1 million genomes over the next five years, as genomics rapidly becomes embedded in the fabric of healthcare. well, it's transformational, in terms of what it means to society and humanity. the vision is that your health record will eventually have a genomic backbone to it and, therefore, a more accurate diagnosis or more accurate treatment will be available to you. olivia is three weeks old. it is her generation that has the most to benefit from genomic medicine, as the growth of dna data gives more insights to enable us all to stay healthier, longer. fergus walsh, bbc news, cambridge. the head of hs2 and crossrail, sir terry morgan, has

announced he's resigning. sir terry has been at the head of crossrail, a new east—west rail link across london, for almost a decade. concerns were raised recently about his dual role with hsz, after crossrail‘s opening was delayed from this month, until autumn next year. the home office failed to act on repeated warnings about how its immigration measures would hit the windrush generation. that's the finding from the government's spending watchdog. the windrush generation are people from caribbean countries who arrived legally after the second world war until 1971. yet the national audit office accused the home office of failing to protect their rights and also warned the full scale of the scandal has still not been established. global carbon emissions are set to hit an all—time high in 2018, according to a new study. researchers at the university of east anglia and the global carbon project say a projected rise of more than 2% has been driven

by a growth in coal use, for the second year in a row. a booming global market for cars has also helped drive co2 emissions to a new high. money for council services is "running out fast", according to the local government association, which represents councils in england. it says local communities will "suffer the consequences", if the government doesn't address the crisis in funding. between 2010 and 2020, councils will have had their overall government grant cut by 60%. next year, almost half of all councils in england will receive no core government grant at all, and will have to rely instead on funding streams such as retaining more in business rates. and there'll be a 5.2 billion funding gap, between the money councils have, and what they need, to provide all the services they currently offer. our political correspondent alex forsyth has been to north yorkshire, where increasing demand for adult social care is putting a strain

on the local council's budget. north yorkshire, a mix of historic towns and sweeping countryside. with miles of rural road and a large elderly population, running services here is expensive and they've had to be squeezed. life was really active previously. when andrew was diagnosed with ms, ten years ago, it drastically changed his active life. now in a wheelchair, he needs support for the most basic tasks and is having to pay more for his care. you don't ever want to think about how you are going to get up in the morning, how are you going to get dressed, whether you're going to get dressed on time. it is a hugely different way of life, a hugely different way. so you don't want the worry of how you're going to get your care. you don't want that question over your head. this charity—run accommodation helps older people live independently. they work with north yorkshire county council, which tries to prevent people of all ages relying on long—term

support where possible, so it goes to those who need it most. so when michelle had a fall in the summer, the council helped settle her back home with her husband. they came and had a look at the house and got it all prepared for us and that enabled me to go back to work. and michelle got her independence from that. i don't think i'd be like i am now if it wasn't for them. ann morgan'sjob is to help people regain and keep their independence. i think it pays dividends in the end because further down the line, they won't need us, which means hopefully they won't need any care. the council here is like many across england, struggling to balance budget cuts with growing demand, not just for adult care but children's, too. the government gave councils an extra £1 billion in this year's budget and says there will be further support when it announces funding plans for next year. councils like north yorkshire will now have to wait longerfor that detail, after the planned

announcement was delayed. they say a long—term solution is urgently needed. we have welcomed the short—term money. it has helped us through winter pressures and things like that. but we need a real, comprehensive reform of adult social care in this country and that includes a long—term funding settlement. we have protected our budgets as much as possible but they can only go so far. with more people needing these vital services, finding a way to maintain them has become a national challenge. alex forsyth, bbc news, north yorkshire. a synthetic drug known as monkey dust has emerged as one of the greatest concerns among police in stoke—on—trent, a drug which is very cheap, and can lead to paranoia and violent behaviour. police across the uk are increasingly worried about the impact of new synthetic drugs, but monkey dust is emerging as one of the most dangerous. our correspondentjeremy cooke has this extended report. when you're on monkey dust, anything can happen. that man, oh, my god, that man.

get out of the way! kevin eagles is up on the roof, out of control. after a few hours, he is talked down into safety and into police custody. he is starting a prison sentence. he was on the roof, chucking tiles. his mum is back at his flat, counting the cost. it's fair to call this a mess. yeah. a mess? it's just devastation. i mean, what's happened here? i've not got a clue. he's just lost his head somewhere, hasn't he? you know, i've invited you here to come and see what a destruction it can do because it is so dangerous. hard to believe the rage and fury that has caused this. i don't know. there's no answer, is there? but then we find the answer. what is this stuff? that is what they call monkey dust. that must be it. £2. what has it done to his life? i'd say it's ruined it.

0k, stay still. your bone is sticking out of your arm. you really need to relax, 0k? this is the reality of monkey dust. stay still for me, fella. he's badly injured. i'm high as a crackerjack. but still raging. just like spice, monkey dust was a legal high. now it is a class b drug and in stoke, a class a problem. why are people taking it? i take it for the buzz, i do. do you want some as well, man? no, thanks. do you see it a lot, monkey dust? it's all over here. what does it feel like when you take it? you feel hot, you feel nice and... like that. have you had any today? yes. every day? yeah. why not? this is why not. rio bailey was a promising young

athlete, a junior champion. but that was then. now rio is on the monkey dust. to see what this drug has done to him and itjust absolutely breaks my heart. rio's dad lives with the constant fear of what happens next. he keeps doing it. he keeps going back to it. he's on the streets, looking out for his son, looking to help anyone on monkey dust. my worst fear is that rio will die from taking the substance, you know, and that's... it's heartbreaking for me to even think about, to even consider that. in this world, rio's not easy to track down but finally, we catch up with him. a few quick words to reflect on monkey dust and the destruction it brings. i cut my wristsjumping through a window. i've also got a cut on my elbow here. they both got infected. i was having to take antibiotics. mentally... i was damaged. what i was seeing was...

was it real or wasn't it real? this synthetic monkey dust is destroying your insides. it's a psychoactive drug. it's destroying you mentally and people know nothing about it. the police are closely monitoring stoke, the impact of monkey dust, and its potential to do still more harm. what we are seeing is, the issue of synthetic drugs is still having a massive effect as well, not as big as heroin and crack cocaine, but clearly there's an issue. is it growing? and that's the point. so you use the example, in staffordshire at the minute, they will still say, despite all their hard work all the joined up work they are doing within the partnership, they are still getting calls every day where people are taking that drug. drugs probation. in stoke, they are fighting back. at the community drug and alcohol service, everyone is battling addiction. some have been on monkey dust. all have seen what it's doing to their town. i had to go away for about 18 months and then i came back to stoke. when i came back, it

had just swallowed up people and spat them out the other end, really. what's going on? i think i've taken something... for years, monkey dust has been ruining lives here, burning through police resources. the fear is that all of this could be heading to a town near you. screaming. jeremy cooke, bbc news, stoke—on—trent. the bbc has seen evidence that a student from bath has set up an extreme neo—nazi group that suggested prince harry should be shot. andrew dymock is believed to have set up the group, as an affiliate of a us group, linked to five deaths already. the bbc team carrying out the investigation obtained extensive evidence of the group discussing its violent ideology. this report by our home affairs correspondent daniel sandford contains some disturbing images from the start. some of the shocking imagery produced by the sonnenkrieg division, the most extreme of britain's new neo—nazi groups.

the violent propaganda, the worst of which we are not showing, includes this picture implying that prince harry should be killed for marrying someone of mixed race. the bbc has infiltrated sonnenkrieg's secret online conversations, reading hundreds of messages including one where the leader of the group, blitz or blitzy, says "kill all police officers." after an investigation lasting several months, the bbc has seen evidence that blitz, the founder of the group, is andrew dymock, a 21—year—old student from bath whose father is a professor of dentistry. he based the group's ideology on a group in the us called atomwaffen division. atomwaffen, which organised what it called hate camps, has been linked to five deaths in america. those include the killing of blaze bernstein, a gayjewish student. the man charged with his murder was a suspected atomwaffen member. at their home near los angeles,

blaze bernstein's parents told the bbc that britain should be very wary of atomwaffen spin—offs. it's like a disease. this group is a disease. and the only way to eradicate it is to figure out where it is and root it out. the uk group, the sonnenkrieg division, was set up this year and believes society needs to be destroyed before being rebuilt as a nazi state. one of the unusual things about sonnenkrieg division is they like to harm teenage girls. we've seen an image, which we have completely blurred, posted by blitzy of what seems to be a teenager in a bedroom at the university. the teenager is naked and has a swastika and runic symbols carved in herflesh. one of the groups main propagandists, who made this video,

was also only 17 years old. this man, according to a source, produced the prince harry poster, we put the evidence from our investigation to him, but he did not respond. andrew dymock said through his lawyer, all the allegations were wholly incorrect and that he was not a member of these groups and any interest he had was associated with his university studies. we went to his home in bath to ask for more detailed explanations of his actions. but he has refused all requests for an interview. daniel sandford, bbc news, bath. world leaders, including president trump and four of his predecessors, have paid their respects at the state funeral of the late president george bush sr, who served as the 41st president of the united states. he died last week at the age of 94 and will buried in his home state of texas tomorrow. the congregation at the national cathedral in washington dc heard tributes to his sense of duty and public service, as our north america

editorjon sopel reports. a nation prepares to bid farewell to the last of the greatest generation, those political leaders who fought in the second world war and then served their country with distinction. the extended bush family looked on as his flag draped coffin was moved to the national cathedral. among the mourners, prince charles, representing the queen, and sirjohn major, prime minister during the first gulf war and close friend of george hw bush. the german chancellor angela merkel had come, ever gratefulfor the role that president bush had played in the reunification of her country. and in the front pew, all of the living former us presidents were there. and of course, the serving president, donald trump, too, who, until george hw bush's death, had been so disdainful of the bush family. but on this day of national mourning, it was also a rare day of national unity for a divided country.

unity there may have been. warmth, there wasn't. the body language as chilly as the december day outside. the eulogy was delivered by his son, the former president george w bush. it was pitch perfect, mixing humour and pathos. i said, "dad, i love you and you've been a wonderful father". and the last words he would ever say on earth were, "i love you, too". to us, he was close to perfect. but not totally perfect. his short game was lousy. chuckles. he wasn't exactly fred astaire on the dance floor. the man couldn't stomach vegetables. chuckles. especially broccoli.