this is bbc news. the headlines: more than 70 mp5 and peers sign a letter urging the government to ensure julian assange faces authorities in sweden, if they request his extradition. the sudanese general who led a coup to overthrow long—term leader omar al—bashir steps down, just 2a hours after he took charge of the country. doctors celebrate a new treatment — called gene silencing — that's seen major success in treating the crippling pain caused by porphyria. a dutch fertility doctor is found to have used his own sperm to father 49 children, without his patients‘ consent. and shakespeare's works are well known, but where in london did he live? we speak to the historical detective who's tracked him down. and the brexit extention and israeli prime minister

benjamin netanyahu's pledge to annex parts of the west bank are discussed in dateline london with carie gracie, in half an hour here on bbc news. more than 70 politicians have signed a letter urging the government to allow the extradition ofjulian assange to sweden, if officials there make a formal request. swedish prosecutors are deciding whether to reopen an investigation into allegations from two women, who accused the wikileaks founder of rape and sexual assault, which mr assange denies. he was arrested on thursday after seven years in the ecuadorian embassy in london. our political correspondent susana meondoca explains.

a lot of them are labour mps, but we've also mps from other political parties, the independent group, change uk is included in there, and you've got some liberal democrat mps as well. it was posted on social media last night by the walthamstow labour mp stella creasy, and basically in this letter, what it says, it urges the home secretary to stand with the victims of sexual violence to ensure the case, the rape case againstjulian assange is properly investigated. it's basically saying that if sweden does decide to go down the route of calling for an extradition process to get mr assange to head there to face those charges, that britain should give them mr assange first, i suppose, rather than the us which also wants to extradite mr assange for different charges on computer hacking. now, in terms of that case againstjulian assange, on the rape allegations which he denies, these were actually put a few years ago to mr assange. the case was dropped in 2017, and the reason that it was dropped is that the swedish authorities were not able to formally notify him

because he was at that time in the ecuadorian embassy in london, and so that's why it was dropped. now, as far as we know, the swedish authorities are looking at whether or not they want to put the case again. they haven't formally asked for extradition proceedings to begin yet, so, you know, i suppose this these various mps kind of getting ahead of things before perhaps it goes down that route. but essentially you could be in a situation where if you've got the us asking for him to be extradited there and you've got sweden asking for him to be extradited to sweden, then home secretary would be in a position to make the decision as to, you know, which takes of those takes precedence. let's speak now to the labour peer and former lord chancellor, lord falconer. he's in our nottingham studio. what do you make of the dilemma sajid javid faces as home secretary

over the decision over extradition? if the swedish authorities seek extradition ofjulian if the swedish authorities seek extradition of julian assange if the swedish authorities seek extradition ofjulian assange on sexual assault charges than the home secretary must decide which one goes first and the law says in considering, and it is his discretion which comes first, he must have regard to the date on which the request was first made and the severity of the competing to charges. now, the americans have chosen to prosecute or seek extradition on the basis of a conspiracy to hack into computers which carries a maximum sentence of five years. it's a lesser charge than they could otherwise may be have considered bringing because they want to be sure they can get extradition. the sexual offences charges in sweden carry on the face of it much higher penalties and would be regarded as more severe. they are also the charges which... or some of them were the charges

whichjulian or some of them were the charges which julian assange went or some of them were the charges whichjulian assange went into the ecuadorian embassy to try to avoid. it looks to me like the swedish charges, if they are brought, have first claim. do you think there may have been a calculation about the americans that they knew that a lot of the original criticism and concern was that the americans want to get him because of the threat to national security so from the huge embarrassment to the american government and they would basically want to prosecute him on the highest possible charges, locking up and throw away the key, and britain should resist that? but by bringing this proposed charge of hacking there choosing a relatively low level offence and that is designed to offer reassurance? i think they have chosen the lesser charge to increase the chances of extradition but the price they pay for choosing the lesser charge is that when it comes to a comparison

with the swedish charges, the swedish charges are much more severe. there is another point as well which is that there is an absolute time bar in relation to the last possible swedish charge, which is 2020, and the american charges obviously take a lot longer to be dealt with, particularly if you wait until the states, that is another reason for favouring the swedish charges of the american ones. someone said famouslyjustice delayed is justice denied and someone said famouslyjustice delayed isjustice denied and it someone said famouslyjustice delayed is justice denied and it has been difficult for the alleged victims of the offences and arguably for victims of the offences and arguably foer victims of the offences and arguably for mrjulian assange himself. in a sense presumably the pressure on the british would be, look, you must make a decision relatively quickly and there is nojustification make a decision relatively quickly and there is no justification for stringing it out. they definitely must make a decision quickly. the length of time it has taken, particularly in relation to the swedish charges, is very much

down to mrjulian assange, because the extradition process had almost reached an end in the middle of 2012 at the point he sought asylum, and the dropping of both the charges in sweden was because he ran away from facing up to the charges. so although, yes, there has been delay which makes it extremely important for both the british and swedish authorities to move as quickly as possible, that is down to mrjulian assange and not down to either the united kingdom or sweden. pleasure to speak to you. thank you for being with us. the general who led a coup in sudan to overthrow long—time leader omar al—bashir has stepped down, after just 2a hours in charge of the country. general awad ibin auf made the announcement after tens of thousands of protesters demanded a civilian—led transition. caroline rigby reports. car horns beep jubilation on the streets of khartoum. for months now protesters have been demanding change in sudan, an end to the 30—year rule of strongman omar al—bashir, but these celebrations

are not about him. they are because the man who led a military coup to topple the president has also resigned. translation: i announce as the leader of the transitional military council that i am stepping down from this position to select someone whose expertise and competence i can trust and on that basis i have chosen the kind brother lieutenant general abdel fattah abdelrahman burhan in succession to me. taking the oath, this is the country's third leader in just two days, an army general seen as less close to the former president who was indicted by the international criminal court for genocide. the military plans to stay in power for two years before eventual elections. they chant but after enduring years of economic crisis and political corruption, many in sudan want even greater change, and transition to civilian rule. momentum here is with the people, not least women, who have played

a major role in this revolution. change in sudan remains precarious but also full of possibility. caroline rigby, bbc news. let's speak to gill lusk now, a sudan specialist and writer. she has covered this story for many yea rs. she has covered this story for many years. thank you forjoining us. were you surprised by the outcome of events ? you mean today or yesterday? both. yes. no, not really in the sense that the protest movement has been so that the protest movement has been so extraordinary in sudan since december, it has grown and grown and been very peaceful, and the people have been very clear that they wa nted have been very clear that they wanted an end to the regime, not just to the leadership of president omar al—bashir. but the general only 2a hours ago

said this is the situation and of the different elements of the security apparatus of the country had made this decision and got rid of him, and we will give you a transition for two years maximum, and that was not enough to satisfy them but then he meekly appears to have accepted his own fate? i think he has bowed to the inevitable really. it was very clear that the protesters were not going to a cce pt that the protesters were not going to accept him. they thought that this was just the regime reinventing itself, the islamic regime of president omar al—bashir reinventing itself, but there are still worry now that this may be happening again. what about the problems that act as a catalyst for this? there are some very severe problems affecting sudan, its economy and its whole way of life for people their... what do you think is the most important thing that a new government in whatever form will have to tackle? it will have to bring democracy and

the protesters a re it will have to bring democracy and the protesters are going to have to believe that is the case. for example, calling for a ceasefire in the areas where government has been fighting the armed opposition, particularly in da for, there has been no mention of this and that is one of the things worrying people, that the new council under the general has not mentioned this and i have not mentioned changing the laws. people are very hostile to the previous regime and they want a secularist democratic state with justice and proper legal systems. the rule of law again. you must be thrilled in a sense to see change coming to sudan because it seems to have been suppressed for so it seems to have been suppressed for so long in this country, and it has had such an agonising 30 years or so of history. what most impresses you about the country? most impresses me? yes. well, i think the uprising or what the sudanese are calling revolution.

it has been absolutely extraordinary and coordinator and not really by the political parties but which bracket, but they are not coordinating it but the sudanese professionals association and other civil society organisations which have been doing this, doctors, lawyers, academics, teachers and all kinds of ordinary people, as your correspondent side, and women have played a prominent role. so have the young people. thank you very much forjoining us. we will speak again i am sure about sudan and what lies ahead. thank you. i hope so. thank you. a 13—year—old boy has died after being found unconscious in a park in south wales on friday night. he was found in the village of ystrad mynach, and was taken to hospital in cardiff where he was pronounced dead. police say his death is being treated as unexplained, and his family has been told. a new type of medicine called gene silencing has been used to reverse a disease that leaves people in crippling pain. it works by fine—tuning the genetic instructions locked in our dna. experts say it could be used for other conditions including

parkinson's disease and alzheimer's. here's our health and science correspondent james gallagher. and the cows, look, moo! sue has endured pain few can imagine. she used to take strong painkillers every day due to a disease called porphyria. sue needed hospital treatment if she had a severe attack but even morphine didn't stop the pain then. i've had a child, i have done child labour but itjust feels like it's never going to end, it is so, so intense, so strong that it's in your legs, in your back and itjust resonates everywhere. it's really, really unbearable. but sue's life has been transformed by a monthly injection of a new type of medicine called gene silencing. this is how it works. inside our cells are genes. they send out messages containing the instructions for running our body but in porphyria an error leads to a build—up of toxic proteins.

gene silencing intercepts the messenger, disabling it and restoring the correct balance of proteins. the study showed gene silencing cut attacks by 74% and half of patients were completely freed from the attacks needing hospital treatment. british doctors who took part in the clinical trial say the impact was amazing. these are very difficult patients to treat and they've had a very difficult time and i'm surprised, genuinely surprised how well it works in this condition and i think it offers a lot of hope for the future. sue is now enjoying life without pain but the implications of this study go much further than sue and porphyria. experts say gene silencing is an exciting new area of medicine with the potential to work in diseases that are currently untreatable. james gallagher, bbc news. the headlines on bbc news: more than 70 mps and peers sign a letter urging the government to ensure julian assange faces

authorities in sweden, if they request his extradition. the sudanese general who led a coup to overthrow long—term leader omar al—bashir steps down, just 2a hours after he took charge of the country. doctors celebrate a new treatment — called gene silencing — that's seen major success in treating the crippling pain caused by porphyria. a trial which freed up more than half a million hours for nhs patients is being extended for three years. it involved re—directing patients to health care professionals other than gp‘s and reducing paperwork. nhs england said the scheme should be in place in three quarters of gp practices by 2022. i'm joined now via webcam byjaimie kaffash, editor of pulse magazine for gps. thank you forjoining us. how does the scheme work?

this was brought in in 2016, and it was money of £30 million given to general gp practices to implement a load of different ways of bureaucracy and one of them is a different kind of health professional but also ways of bringing an efficient telephone systems and ways of using online consultations more... it was hoped this would save gps time with bureaucracy. now, speaking to gps ourselves, the first reaction we get when we mention this is what is that? although there has seemed to be encouraging results, i think it has not really resonated with the wider gp population as a whole, really. one of the things that you talked about was telephone appointments, and people think, if i have a telephone appointment i can't see my doctor, but it encourages some people who spoke to a doctor and decide they don't really need to see him or herand decide they don't really need to see him or her and that presumably has been quite useful... even though it involves time it is a more efficient

use of time. gp practices have been doing telephone triage for a long time and they will get the gps or nurses to speak to the patient first to see whether an appointment is necessary. it has been going for a long time and not just protein it has been going for a long time and notjust protein here and it helps patients —— it is notjust been brought in here. patients will often been brought in here. patients will ofte n wa nt been brought in here. patients will often want to see the gp and be examined, so there should be online consultations as well as telephone consultations... there is fear over the safety of online consultations and whether agp can really diagnose and whether agp can really diagnose a patient properly if only seeing them online and not face—to—face. but some gp practices... it seems to work for some gp practices. your magazine reported extensively on the pressures on general practitioners, not least the practicalfact practitioners, not least the practical fact that the age of the gp population is ageing and a lot of people are going to retire are not enough people are coming in to fill behind them. how much difference

could these systems make given the biggerfactors on could these systems make given the bigger factors on performance? i think that is the main thing to ta ke i think that is the main thing to take from this, that this is a drop in the ocean and it does not mean your audience's waiting times will drop dramatically. there are two real factors affecting waiting times, the lack of gps and an increase in patient demand. obviously we are becoming a more elderly population, living longer with more conditions. morbidity... you not just with more conditions. morbidity... you notjust going to a gp practice with a simple condition but a lot more. obviously it is hard to cut patient demand but one thing we can doi patient demand but one thing we can do i think is for the government and nhs to stop encouraging patient demand that is not necessary. for example, matt hancock talked about how great it was he had jane testing and he was able to go to the gp and

talk about potential conditions he might have in the future —— genetic testing. we do have bodies which look at the evidence and do decide what kind of thing you should be looking at four in the first place. this is not evidenced, nothing he talks about but increases patient demand. something like that has a negative on waiting times far worse than this is going to save time. thank you, good to speak to you. a dutch fertility doctor accused of using his own sperm to inseminate patients without their consent has been confirmed as the father of 49 children. dna tests revealed that jan karbaat, who died two years ago, impregnated their mothers at his near rotterdam. our correspondent anna holligan is following the story in the netherlands... jan karbaat called himself a pioneer in the field of fertilisation and i was in the courtroom in 2017 sitting among children who were side by side, clearly sharing some of the

doctor's distinctive physical features, but uncertain as to whether they were among brothers and sisters. this has confirmed that suspicions that he was indeed their father. it was the result of paternity tests and they really had to battle to get them because doctor jan karbaat‘s family initially objected, saying it's not what the doctor wanted, but then after his death in 2017, they harvested dna from his hairbrush and toothbrush, and that was then locked in a safe, and that was then locked in a safe, and one of the suns came forward and agreed to give his dna —— one of the daughters and sons. the children call themselves the donor kids and there was a match and then they could check the paternity against the doctor's dna that had been kept safe. one of the young women, young women and men now, one of them told me she thought her father had a god complex and believed he was doing them a favour by passing on what he

saw as his superior genes. obviously, not the way the children saw it but at least now they say they have some form of confirmation. we might be able to hearfrom they have some form of confirmation. we might be able to hear from joey, who is one of the children who fought this case... translation: who is one of the children who fought this case... translatiosz means a lot and at last we can close this chapter in peace and i can carry on with my life now. the search took 11 years. they still don't know how many children may have been fathered by this man. a historian believes he's pinpointed the location of the london home where william shakespeare wrote some of his most popular works, including romeo and juliet and a midsummer night's dream. evidence suggests the bard took up residence in the parish of st helen's bishopgate in the late 1590s. theatre historian, geoffrey marsh, cross—referenced various official records to find the exact location. it had been known since the 1840s that shakespeare lived in this parish. but the company of leather sellers, they bought this huge property in 151t3 and they still own it.

so i started combing through the leases and remarkably they've preserved them and in there is not shakespeare's lease, but the leases of two people who must have lived next door to him. and so we can locate those and from that we can work out pretty closely, not exactly, but really closely — within a few yards — where he was living. an intriguing prospect. now let's look at sport with a round up of a busy sporting weekend at the sports centre. we will start with the formula 1. valtteri bottas will start formula one's one thousandth race from pole position. the championship leader beat his mercedes team mate lewis hamilton byjust two hundredths of a second in qualifying for the chinese grand prix. the ferraris of sebastian vettel and charles leclerc will line up behind them.

saturday is traditionally called moving day at the masters, but the big names in the field could have already made their move. tiger woods is part of a masters leaderboard that's stacked with superstars. the 1a time major winner is just a shot behind the leaders at augusta... there are five of them... they've all won majors too. tiger's in contention on six under par, despite almost being injured by a security guard... andy swiss reports. it was a day which began soggy and was later interrupted by a thunderstorm but although the weather was not great, the gulf certainly was, most notably tiger woods, is 22 years on from his first masters title he was thinking about rolling back the years in spectacularfashion. after struggles with fitness, this was not what he needed — a security guard clattering into his ankle. it hardly seemed to affect him. tiger woods stirred the augusta crowd with stunning golfjust one shot off the lead and hoping to complete what will be the most extraordinary story. others found life far more

difficult. the remark of roy hitting it into a golf buggy at one point, seven of the pace, his chance assuming distant. but ian poulter‘s certainly aren't, another fine display for the englishman with just two points back. european challenge is being led by francesco, the open champion, one of five players at the top with a tightly packed leaderboard. this masters is still very much wide—open. at the halfway point it is intriguingly poised but the big question for many will be, can tiger woods turn his promising position into what would be one of golf‘s most remarkable victories? andy swiss, bbc news, augusta. and remember, you can watch live and uninterrupted coverage of the third round of the masters on bbc two from 7.30 this evening. tiger woods has been paired with ian poulter — they tee offjust after 7pm uk time. anthony crolla sez he's fine despite suffering a brutal knockout

defeat to ukraine's vasyl lomachenko, who retains his wbo and and wba lightweight titles. lomachenko is a double olympic gold medalist and one of the best pound for pound fighters in the world... he dominated the fight in los angeles, and a right hook in the fourth round ended crolla's hopes of becoming a two—time world champion. in the premier league, tottenham will take on already—relegated huddersfield in today's early kick off. a win would move spurs into third, a point ahead chelsea who don't play until tomorrow. last night, newcastle united moved ten points clear of the premier league relegation zone after a much needed win over leicester city. the only goal of the game coming from the spanish striker ayoze perez in the first half. that win pushes newcastle up to 13th in the table. we are we a re really we are really pleased with the one goal away, clean sheet, three points. good points in the table but

all you have to do is enjoy today and be ready for the next one. and we will try to get three points in the next game. the australian horse winx is said to have achieved racing immortality after winning herfinal race to extend a victory run to 33. the mare was described as "an australian icon" and the greatest of all time as she crossed the line to win the queen elizabeth stakes at randwick racecourse this morning in sydney. the eight—year—old mare, ridden byjockey hugh bowman, is unbeaten since april 2015 and is now retiring. that's all the sport for now. hello there. we've got more of the same really through the rest of this weekend. it's going to remain on the cold side and we have got stronger winds as well, east to south—easterly winds are picking up which make it feel colder. most places will be dry, there will be some sunshine around but there will be some more frosty nights and early mornings as well as we had early this morning. a look outside from earlier on, this is the picture in county antrim and it is this part of northern ireland that will probably see the best of the sunshine across the country.

here we are in woking in surrey with some blue skies and probably staying dry here today, though there are some showers coming in across east anglia into the south east of england today, one or two could be heavy, perhaps with some sleet and hail. but away from here it is going to be dry, some lengthy spells of sunshine, some fair weather cloud. sunshine is a bit hazy in northern ireland, west wales and the south—west of england and here we have got some stronger winds as well and it willjust make it feel colder. not so bad if you are in the sunshine but in the shade, those sort of temperatures are pretty chilly for this time of the year, 8, 9,10 celsius, that sort of number. as we head through this evening, those temperatures will drop away fairly quickly underneath the clearing skies, any showers retreating to those north sea coasts. but we do have a weather front approaching northern ireland, so a lot more cloud here, so too across west wales and maybe a little rain in the far south—west of england, so much milder here. but away from here towards central and eastern areas, it will be cold and frosty once again. so, a cold start to the second half of the weekend. still a little rain perhaps over towards cornwall, the isles of scilly and more cloud and still a stronger wind. elsewhere, after a sunny start, we will see

cloud amounts increasing, probably more cloud than we're seeing today and as a result, it is going to feel quite cold once again and those temperatures are struggling up to 9 or 10 celsius, so below parfor this time of the year. as we head into the beginning of next week, well, we've still got the area of high pressure toward scandinavia, drawing in colder air, keeping these weather fronts at bay, but strengthening the wind so a cold and rather blustery start to the new week. we still have high pressure as we move further into the week up towards easter, but the position of the high will change, we'll draw in some slightly warmer airfrom the south—east and temperatures are going to rise, which is good news for the easter holidays and as we head up to easter, it is going to be warming up. that is it from me. goodbye.

hello and welcome to dateline london. i'm carrie gracie. this week — a whole six months for comedians to make brexit trick or treatjokes as the uk wins an eu extension until halloween. but who has a better plan on how to use the time? and benjamin netanyahu on the brink of a 5th term. will the israeli prime minister now annex parts of the west bank? my guests today, israel analyst jonathan sacerdoti, ian martin of the times, italian writer analisa piras, and abdel bari atwan, writer on arab affairs.

welcome to you all. do not waste this time, said european council president donald tusk as the eu granted the uk a 6—month extension. but what constitutes time well spent in the context of brexit? ian, you first. let's look at a timeline for the next six months. we could usefully do that for everyone involved in brexit. they have easter recess. will they use the time to reflect as the prime minister suggested are well they lay in a darkened room garden on easter eggs? the latter i think most of us. it has been like, like we have seen in fawlty towers, this is the next best thing, this british farce. people in westminster are tired and stressed on both sides. when people are tired

and