vietnamese families fear their children are among the 39 people who died in the refrigerated lorry in essex. the brother of 26—year—old pham tra my says he last heard from her on tuesday night, when she sent text messages saying she couldn't breathe. tonight, police are asking for help. i would also like to make an appeal to anyone living illegally in this country, who could help our investigation. please come forward and speak to us without fear. it comes as a fourth person was arrested at stansted airport on suspicion of manslaughter and conspiracy to traffic people. we'll explore the issue of criminal gangs trafficking migrants. also tonight... boris johnson tells jeremy corbyn to "man up" and back an election, as the eu agrees to another brexit delay — but won't decide the date until next week.

the teenagers being sold class a drugs on social media. we hearfrom one mother whose 13—year—old son died after taking ecstasy. if they don't start making an example of it, it's just going to go on and on and on, and spiral, and people will get away with it, making money. on what? on families being torn apart. and a huge weekend at the rugby world cup, as england and wales try to make it through to the final. and coming up on sportsday on bbc news, leicester run riot at struggling southampton, scoring five goals in the first half, on their way to second in the premier league table. good evening and welcome

to the bbc news at ten. several vietnamese families have told the bbc they fear their relatives could be among the 39 people found dead in a refrigerated lorry in essex. one of them is 26—year—old pham tra my. her brother says she hasn't been heard from since she sent text messages on tuesday night saying she was dying and couldn't breathe. her last message was sent two hours before the trailer arrived at the purfleet terminalfrom belgium. two other vietnamese nationals have also been reported missing — a 26—year—old man and a 19—year—old woman. police have now arrested a fourth person in connection with the deaths. our special correspondent ed thomas reports. this is pham thi tra my. she's 26 and from vietnam. tonight, she's missing. her family fear she was one of the 39 people to lose their life in the refrigerated container found in essex. at the exact time the container was crossing from zeebrugge, she sent this disturbing message.

" i' m really, really sorry, mum and dad. "my trip to a foreign land has failed. "i am dying, i can't breathe. "i love you very much." her brother wanted to broadcast this appeal on the bbc. translation: my sister went missing on the 23rd of october on the way from vietnam to the uk and we couldn't contact her. we are concerned she may be in that trailer. we are asking the british police to help investigate, so that my sister can be returned to the family. the bbc has also spoken to the family of nguyen dinh luong, a 20—year—old man also missing tonight. the vietnamese embassy in london is now working with uk authorities to identify any victims suspected of being from vietnam. today, this investigation moved to cheshire. police arrested a 38—year—old man and a 38—year—old woman from warrington on suspicion

of conspiracy to traffic people and manslaughter. in essex, detectives are continuing to question the 25—year—old lorry driver, named locally in northern ireland as mo robinson from county armagh. and this evening, police confirmed they'd also arrested a 48—year—old man from northern ireland at stansted airport in connection with the deaths, and made this appeal. i would like to speak directly to anyone who thinks their loved ones may have been in the trailer. i know you may be worried about speaking to the police, and i would like to reassure you that we just want to be able to give the victims' families answers about what has happened. all day, the delicate process continued, private ambulances under police escort removing the bodies from the refrigerated container. one by one, postmortem examinations will be carried out, as police try to find out who they were and how they died. what's this noise, the noise? the fridge working. the fridge working? yes.

that's the sound of the fridge? yes, i show you. wojciech has been transporting refrigerated lorries for two years. it goes 20,21. temperatures can get as low as minus 25. what's inside it? i don't know. you don't know what's inside? i don't know. sealed here, and i can't open this and check. he's not allowed to break the seal, but every move he makes, is followed by a gps tracker. because it's expensive and they show where i am... the trailer has the gps? ..where is this truck. and we've learnt more about the gps movements of the refrigerated container found in essex. sources say tracking gps data shows the container left monaghan in ireland on october the 15th, then made trips to dublin and wales, before crossing from dover to calais on the evening of october the 16th. once in mainland europe, it appears the container travelled between belgium and france,

visiting dunkirk, bruges and lille, before it made its finaljourney from zeebrugge to purfleet. around half an hour later, it had been picked up by a lorry and all 39 bodies discovered inside. for three years, there have been security concerns over purfleet, warnings smuggling gangs were targeting the port. they're dishevelled. some of them have got phones and they're smart. this is now an international investigation, as police search for the truth and answers for all 39 victims. ed thomas, bbc news, tilbury docks. as we've heard, people are willing to pay thousands of pounds to smuggling gangs in an attempt to get into the uk. our correspondent lucy williamson found other vietnamese people at a camp in northern france, who are trying to get across the channel. an hour's drive inland from the french coast, a dozen vietnamese men wait for a phone call from the man

they call the boss. an afghan, they say, who opens trailers in the lorry park nearby and shuts them inside. this man paid 30,000 euros for a prepaid journey from vietnam to london, via russia, poland, germany and france, organised by a vietnamese contact back home. translation: i have some vietnamese friends in the uk who will help me find jobs when i get there. these friends helped me get on lorries or container trucks to go across the border. security is much less tight in the nearby lorry park than around the ports further north, but few people here have managed to get past the border controls. the men in the camp told us that it wasn't easy to reach the uk that way and they'd been stopped several times by border guards. but we're told that for those who've paid more for their passage, this is simply a transit camp before they are taken on the final leg of theirjourney.

a local volunteer told us they'd seen vietnamese and british men visiting migrants here in a mercedes. and that once migrants arrived in the uk some went to work in cannabis farms, after which all communications stopped. the man tells me he needs a job in the uk to pay back the loan for his journey. translation: we can do anything, he says, construction work, nail bars, restaurants, or otherjobs. a report by one of france's biggest charities found that smugglers were telling vietnamese migrants refrigerated lorries gave them more chance of avoiding detection. no one here had heard about the 39 people found dead this week. this journey‘s about freedom, one said. lucy williamson, bbc news, northern france. our home affairs correspondent daniel sandford joins me now. what have we learnt about how

sophisticated this operation is? as we've been investigating this people smuggling route from vietnam over the last 2a hours, what's been so over the last 2a hours, what's been so striking is how incredibly organised it is, relatives and vietnam were very aware of where their young relatives had got two on their young relatives had got two on the journey. they were getting regular updates all along the way, until those stopped on wednesday morning, and that was why they were so morning, and that was why they were so worried that their relatives might have been caught up in this tragedy and why it was they contacted the bbc. some of them had only paid deposits for the journey to britain and they were going to pay the full balance of £30,000 on arrival, and some of the families have actually been given their money back by people smuggling gangs because it's thought that their relatives might have died. the route many of them seem to have taken has been from vietnam, china, and then to get false papers there to fly to europe, and only the last leg of the journey in the back of a lorry to the united kingdom. ii9—year—old girl phoned her parents saying i'm

turning off my phone now, as she went into a container, but they've never heard back from her, and of course there are the tragic texts from pham thi tra my saying, sorry, and goodbye, as she apparently suffocated in the back of the container. this was industrial, organised people smuggling, big profits and big risks, and relatives we re profits and big risks, and relatives were following it all by smartphone, right up to the very tragic end. daniel, thank you. borisjohnson has told jeremy corbyn to "man up" and back a december general election. the labour leader says he'll only agree to one if the prime minister rules out a no—deal brexit. mrjohnson, meanwhile, says he would agree to an extension to allow mps more time to debate the brexit bill — if they supported a poll before christmas. eu leaders are expected to grant britain a further extension early next week after the prime minister was forced by parliament to request one. there is some flash photography in this report from our deputy political editorjohn pienaar.

it looked easy enough. i can't make the scissors work. can't make the scissors work, can't get an early election either. you run the world. i do. no, no, idon‘t. run the world ? as if! he needs labour votes to make a quick election happen, and jeremy corbyn‘s holding back, so... we can have more debates on brexit, if that's what he really wants, but they've got to agree a deadline. time for corbyn — man up, let's have an election on december the 12th. he's campaigning as if the election‘s started. downing street even suggested the government would just ask again and again for an election if mps said no, virtually go on strike from doing anything else. really? isn't that an irresponsible way to go about things? no, no, sorry, ithink you are totally confused here. we are going to be governing in the interests of the country. so maybe no government strike after all.

hello again, welcome back... but what will labour do? the party's split, and jeremy corbyn‘s in no hurry to give the pm the quick election he wants. for now, he's saying no election until there's no chance at all of leaving with no deal. i hope the eu grants an extension. my position is we've got to get no—deal taken off the table first, because it would be catastrophic forjobs and businesses. for brexit, as one door opens, another‘s closed. have a good day. no comment. it was a very good discussion. brussels' chief negotiator was meeting eu ambassadors and keeping the uk guessing. while mps wait to see what kind of extension‘s offered, the eu's waiting to see what westminster decides. westminster already seems paralysed. if an election‘s blocked next week, politics could be reduced to a game of who blinks first. an early contest seems inevitable, but who will yield? the snp want to seem more up for the fight than the others. the lib dems want a contest, too,

but if brexit‘s approved first, how can they campaign as the party to stop brexit? we need to have the extension secured and implemented before we can consider a general election so that borisjohnson does not use the time available to take the country out on no—deal. what i want is the opposition parties to come together with a vote of no confidence to bring this government down to move to a quick election. how long has he got to stay? hopefully, we can have him out at the end of next week... out by next week — the young boy, that is, not the uk. the pm can only wish and wait. john pienaar, bbc news, westminster. the united nations has condemned iraq's security forces for using extreme violence against anti—government protesters. at least 25 people were killed today and almost 2,000 were injured as the demonstrators took to the streets once again.

they're demanding an end to years of civil conflict, political corruption and economic hardship. parents are being warned that they are living in ignorance about the way children and teenagers are being targeted by drug dealers on social media offering cheap class a drugs. since 2017, at least a dozen children under the age of 16 have died in the uk after taking ecstasy. our correspondent hywel griffith has this special report. you do, you think you're invincible as a child, you know? still grieving, still confused. it's six months since tatum lost her little boy. i think i didn't want it to be real. you don't want to believe it or something. i was thinking, no, this is somebody else, it's got to be. it can't be carson. 13—year—old carson price died after taking ecstasy in this park. his mother's been told it was sold to him through a snapchat message on his phone forjust a few pounds. when they told me the cost as well, to know what my son's life,

how much that cost... it was too easy, as easy as going to buy sweets in a sweet shop. you know, it was advertised on snapchat, meet someone openly, in broad daylight... here? and that's how easy it was. carson is one of at least a dozen children who have died in the uk since 2017 after taking ecstasy, in a trade which has passed most adults by. but not these teenagers in cardiff, who tell me children are being targeted by drug dealers online and in the classroom. i've known people take them as young as 12, and it can start off like marijuana, but it can really quickly grow to ecstasy. that person who's in the library who is revising is also a drug dealer part—time, because it's such fast money. you can look outside your window, there's about eight kids running back and forth. you know exactly what they're doing. a lot of drugs are actually sold off snapchat, just simply, so accounts would be made,

they're kind of hard to track, they'll approach you and they'll deliver to you as well. snapchat has told the bbc there is no place on its messaging service for drugs. it encourages users to report illegal activity. when the police carry out raids, this is what they find. ecstasy tablets are now at least double the strength and 80% cheaper than they were in the 1990s, making them more accessible than ever. you don't have to go to an unknown house any more. there are no drug dens. it's almost become respectable. it's a text message, an arrangement made very often by phone for a cost, really visible to the public, often not to the police. what is visible is the harm to young lives and the helplessness some families feel. carson was only 13. it's going to get younger, if they don't start making an example of it. it's just going to go on and on and on and spiral,

and people are going to get away with it, making money. from what? from families being torn apart. the home office says it is concerned by the rise in use of class as. it's awaiting the findings of a major review to understand exactly who is most at risk. hwyel griffith, bbc news. alzhiemer‘s is the most common form of dementia and there's no cure for it. but now, scientists believe they could be on the cusp of a breakthrough, after a drugs company said it had the first treatment to slow alzheimer's. dementia is the single biggest cause of death in the uk. 850,000 people are living with some form of it, and that figure is expected to rise to around two million by 2050. our medical correspondent fergus walsh reports on the alzheimer's drug which was deemed a failure just six months ago. i was there, right there, in the chair. charman was in the middle of receiving biogen‘s experimental alzheimer's drug in march when her consultant ran

in and said the trial was being halted immediately. i was shaking, and this was devastating. yes, it was. and very unexpected news. it was. it was a big shock. biogen said the drug, called aducanumab, simply didn't work, but after analysing more data, it now believes it does slow alzheimer's in higher doses. did you feel it was working? yes... ..yes, idid. if you can you tell me the name of this animal? charman was diagnosed with alzheimer's three years ago. and that's one of those... you know. . .! it affects her language skills and she often struggles to find words. i do know it but i can't say it. her husband philip is relieved her condition has not got significantly worse, maybe because of the drug. i think it made a difference. she's still the person i was married to for 35 years and we're still doing things like this.

i don't know whether the drug worked but what i know is that my wife is still the person i knew. yeah. biogen said patients on a high dose of aducanumab had 23% less cognitive decline after 18 months than those on a dummy drug. it helped them retain life skills, like being able to do household chores. abnormal amyloid, then it will show up as red... aducanumab is designed to clear amyloid, an abnormal protein which ravages the brain, so could it be the wonder drug scientists have spent decades searching for? i have to be cautious here because of what's happened in the past. so, i hope we have the first drug that's going to slow alzheimer's, but i have to see more to be fair to my patients and the people that have got hope. but if we do, it would be enormous? yeah, it would be the biggest thing that's happened in alzheimer's, ever. and medical regulators will be

poring over all of biogen‘s as—yet unpublished trial data before they decide whether to grant it a licence. they'll be very cautious indeed. it's relatively immature data. they'll be looking incredibly closely at that and normally what they would want to see is a second study, to confirm those results. if aducanumab passes all its regulatory hurdles, it's still likely to be another two to three years before it comes on the market here in the uk. it will undoubtedly be expensive, but it could also be transformative for patients, giving them crucial extra years of quality life. and enjoying life together is what matters to charman and philip — living with dementia, not defined by it. fergus walsh, bbc news. all week pressure has been increasing on donald trump over allegations he broke the law by asking ukraine's leader to dig up damaging information on the son of his democratic rival,

joe biden. that's led to president trump being subject to an impeachment inquiry — a process where those in high office are investigated for serious misconduct, which could ultimately lead to them being removed from office. but what impact is this having on voters in the run up to next year's presidential election? nick bryant has been to pennsylvania to find out. # everybody dance now...#. the halloween parade in the working class town of northampton, pennsylvania. a traditionally democratic community that twice voted for barack obama, but which in 2016 helped send donald trump to the white house. his presidency has provided a sugar hit for the local economy. unemployment here has fallen, there's a sense of economic resurgence. so the horror story in the nation's capital comes not from the president, but the democrats trying to remove him from office. donald trump? i like the man! what about the impeachment inquiry, do you think it should go forward? no, i think all that's silly.

it will waste so much of the taxpayers' money and stuff on all this craziness. i think it's a farce. i think they're making up everything that they can. i think that he's not doing a bad job, it'sjust he's not a politician and he's not trying to kiss anybody's bleep. these are the carcass—like old steel mills that provided the cradle for the trump presidency, and the rust belt political terrain that will decide next year's presidential election. if the democrats can't win back pennsylvania, they'll struggle to regain the white house. one of the reasons why donald trump became a working class hero in these blue—collar communities is that he presented himself as a fellow victim of elite sneering and establishment condescension. with impeachment, he's using the same playbook again, claiming the democrats are trying to subvert the democratic will of the people here who voted for him.

so much depends on lifelong democrats, such asjoe and bobby, who last time voted trump. they put him through the dry cleaner with the mueller report and if you can't get anything on him with the mueller report, you're not going to get nothing on him anywhere else. he's done what he said he was going to do. everything hasjust been better and it's tough to unseat president when the economy is as robust as this is right now. it's the loyalty of these rust belt voters that offers donald trump something of an insurance policy from being removed from office. if impeachment ends up in a senate trial, then his fellow republicans will decide his fate and the fear for them is enraging his personal base. nick bryant, bbc news, pennsylvania. rugby now — and it's a huge weekend for both england and wales at the world cup injapan. coach eddiejones has made a number

of changes for england's semifinal against new zealand tomorrow. meanwhile, the welsh have had to deal with injury concerns ahead of their crucial clash against south africa on sunday. from tokyo, our sports editor dan roan reports. they weren't the conditions england would have chosen to train in, but nothing was going to prevent final preparations for the biggest game of their lives. the reign of eddiejones began after the last world cup ended in failure, but having guided this team to the brink of the final, the head coach told me just how much it meant. i'm pleased we've put pride back into english rugby. i'm pleased for this group of players. a lot of them had to endure 2015. it was a tough time for them. they've been exceptional in the way they've attacked this world cup and saturday's a great opportunity for us to attack the new zealanders. 2a years ago, england met the full force of the all blacks in a world cup semifinal. the four tries scored by the late greatjonah lomu giving rugby some

of its most iconic moments and adding to the mystique that surrounds a team known as the greatest in sport. from tv commercials to billboards, the all blacks' popularity here injapan is obvious, as they aim for a third successive world cup triumph. but one of the team who lifted the trophy in 2011 told me the reigning champions have their work cut out. you believe england can win this game, against new zealand? oh, for sure, 100%. i'm nervous! really? i'm nervous, i'm nervous, mate. i've played england before and just seen how quality they are throughout the world cup. yeah, like i said, it's going to be a cracking match. wales also trained at the yokohama stadium earlier, ahead of their semifinal against south africa here on sunday. the six nations champions have struggled with both form and fitness injapan but are intent on giving their legendary coach the perfect send—off in his final tournament. can you just sum up, though, what it would mean to you to get wales to the final for the first time in their history? if we could make the world cup final with the player numbers that we've got,

it will be some hell of an achievement. i'm probably the greatest optimist, in terms of i always go in there and believe something's possible. japan gearing up, meanwhile, to host a defining weekend for british rugby. we've had the bad game, now let's put that behind us and i think we can go all the way to the final. the fact that new zealand are switching their team around, which they didn't do the whole of the last world cup, i think they're on the back foot. japan 2019 was already a very special world cup — the first to be staged here in asia. but now, england and wales have the chance to change the course of rugby history and set up what would be the tournament's first ever all—british final. dan roan, bbc news, tokyo. finally, leicester city created a little bit of premier league history this evening at southampton. james madison to take and he makes

it eight! this stunning free kick put leicester 8—0 ahead — and saw them record the biggest—ever away win in premier league history. thenjamie vardy‘s penalty gave him a hat—trick and the 9—0 final score equals the biggest—ever win. that's it from us. now on bbc one, time for the news where you are. have a very good night. hello and welcome to sportsday. i'm lizzie greenwood—hughes. the headlines tonight... leicester run riot at southampton — equalling the premier league record — scoring 9 goals on their way to second in the table. he's in the eye of the storm but eddiejones is the epitome of calm ahead of their world cup semi—final.

and britain's golden boy of swimming — adam peaty invites us to watch while he has his latest tattoo! so a busy sportsday, all the rugby to come but we're starting with football and leicester's incredible 9 nil victory over southampton. it equals the premier league record and it moves them up to second place in the table — while conversely — the huge scoreline means southampton now drop into the bottom 3. austin halewood reports. a night for the premier league purists, torrential rain on the south coast and a warning of the nightmare about to come, these visiting foxes pack one heck of a bike that my fight and then chilwell

finishing the move for lester and for the saints a double blow, the tackle and the build—up spotted by va are. that fall back shown rad and southhampton down to ten after ten and it only got worse, much worse. the call for that foxes and the hampshire rain and two minutes later they were in again and this time hammering and with the home fans heading home. lesterwade hammering and with the home fans heading home. lester wade determined to get there with a bang and he got his second before of course jamie vardy joined the party. his second before of course jamie vardyjoined the party. the foxes with five before half—time. a second half was just the same with a hat trick, before vardy got his second in the foxes running riot and southhampton. perhaps the pick of the goals came from james mattison with this free cake and before jamie vardy finished his hat trick from the spot and made it nine. the

biggest away when an premier league history. lester could do another lester could they? there's a huge weekend of rugby ahead for both england and wales as they prepare for their world cup semi—finals. england are first up, they play reigning champions new zealand in yokohama tomorrow morning. head copach eddiejones has been speaking to our sports editor dan roan, who asked him how to beat a team that hasn't lost a world cup match in 12 years. new zealand you cannot sit and be a spectator, you have to be on the stage and making the script and we plan to make the script on saturday. only a few months ago, i remember a member of the state six nations showing a good start and then you ta ke showing a good start and then you take the mental block out and how have you address that and a short space of time? a lot of it is experience and you from experience, one of those things where generally

some things you can't take and