the first human trials in the uk for a coronavirus vaccine are expected to get underway. scientists at oxford university plan to test it on 500 volunteers by mid—may — if successful, it would then be given to thousands more. i benefit too, you know. it's not a selfless act. i am part of the community. and if we find a vaccine, then we all benefit. but england's chief medical officer has said a drug is unlikely to be available this year. also this lunchtime: 20,000 households in england are being contacted from today, to take part in a study tracking coronavirus in the general population. scotland's first minister sets out how the lockdown might be eased — but says now is not the right time.

0ur steps, when we take them, will need to be careful, gradual, incremental and probably quite small to start with. the economic impact of coronavirus — government borrowing could jump to its highest level in peacetime history. and one of the nurses thanked by boris johnson for watching over him in intensive care, says her team was just doing itsjob. he was just another patient that we were trying to do our best for. so, it was business as usual. and coming up on bbc news, phil neville will leave his role as england women's manager when his current contract expires next summer.

good afternoon and welcome to the bbc news at one. scientists at oxford university are expected to begin the first trial on humans of a possible vaccine for coronavirus. the team says if all goes well, they hope to have a million doses ready by september. yesterday, the government's chief medical adviser warned that it was unlikely a vaccine would be ready this year, and social distancing measures would have to remain until one was found. in other developments, 20,000 households in england are being asked to take part in a study to track covid—19 in the general population. scientific advisers are expected to tell the government they don't think people should be obliged to wear face masks to help combat the virus. business output has fallen at its fastest rate on record — and new figures about government borrowing have underlined the scale of the damage done to the public finances. and scotland's first minister,

nicola sturgeon, has set out her strategy for exiting the lockdown. we'll have more on this in a moment. but first, here's our health correspondent, jane dreaper. the faces of lives lost in this medical emergency. more than 18,000 people in the uk who had coronavirus have now died. the virus is still a new one but scientists at oxford university have worked quickly to get to the point where they hope to start testing a potential vaccine on 500 people. developing and producing any successful vaccine will take many months. we are not going to see a vaccine available and proven and tested and ready to go in the next few weeks. it is going to be somewhere down the line before it starts. it is good news it is happening but we have to continue to focus on what is working in terms of flattening the curve and are dealing with this virus right now. half of

the volunteers received the potential coronavirus vaccine while the other half will be given a job that protects against meningitis. they will be told which they will be getting what they are happy to be pa rt getting what they are happy to be part of this crucial research. this virus is affecting everybody in society. it is affecting my parents. i benefit too. it is not a selfless act. i i benefit too. it is not a selfless act. lam i benefit too. it is not a selfless act. i am part of the community. and if we find a vaccine then we all benefit. so it's a small, well—managed, benefit. so it's a small, well— managed, well—regulated risk that i feel able to take. everyone is facing some worry and anxiety at the moment, be at the household finance, be it worrying about their family or health or friends. some people are more at risk than others. god forbid about bereavement and loss. i don't think the risks of the trial are significantly greater than any of the reality is we all face. there has been heated debate about whether the public should wear face masks. scientists advising government will tell ministers later what they think. they're not

expected to recommend the widespread use of medical masks and doctors point out that other face coverings have drawbacks. we think it potentially means that people are touching their mouth and their face more often. the masks may become contaminated with other people's coughs and sneezes. and also when people take them on and off again. ata time people take them on and off again. at a time when we are relying heavily on science we have to be honest and say that sometimes the science does not give us perfect a nswe i’s , science does not give us perfect answers, and this is probably one of those times. 25,000 people will provide nose and throat swabs to find out more about the spread of coronavirus. this will help researchers working on new tests and treatments. lockdown continues in the meantime. and we're being warned that any move away from the current restrictions will be very gradual. if people are hoping that it suddenly going to move from where we are now in lockdown, suddenly into everything is gone, that is a wholly unrealistic expectation. we are going to have to do a lot of things

for a long period of time. the question is, what is the best package? this is what we are trying to work out. the government says it needs to be confident of the rate of infection has gone down to a manageable level before ordinary life can begin to resume. this could mean more widespread testing and also a system for tracking who people with the virus have come into contact with. jane draper, bbc news. 0ur health correspondent, nick triggle, is here. in particular tell us more about the surveillance programme launched today? well, if you remember, the start of april the government announced its testing strategy and they were five pillars to that. the surveillance testing programme is one of those pillars. as mentioned, 25,000 volunteers one of those pillars. as mentioned, 25, 000 volunteers have one of those pillars. as mentioned, 25,000 volunteers have been recruited to be tested regularly, to see if they have the infection. eventually that will increase to 300,000. the importance of that is to work out how much of the virus is circulating in the community, and

crucially, if the rate of infection is increasing. at the moment we are reliant on using hospital admissions and estimated back from their how much viruses in the community. now, if we can detect it earlier, it will help us get out of lockdown, gradually easing those restrictions and seeing what the impact of that will have. but we also need to have widespread testing in the community for the general public too. that will be to help contain any local outbreaks, to identify cases, trace contacts and isolate them if need be. the government have set a target to achieve 100,000 tests by the end of the month, that is next week. currently there are only 40,000 tests available. we're only testing half of that. there is still some way to go. we will hear more about that every daily televised briefing later today. for now, thank you. nick triggle. scotland's first minister nicola sturgeon has set out her strategy for exiting the lockdown. she said any easing of restrictions

would be done in phases, and warned that life wouldn't return to normal soon. let's speak to our scotland correspondent, alexandra mackenzie. and nicola sturgeon has only been speaking in the last few minutes. bring us up to date with everything she has outlined ? bring us up to date with everything she has outlined? yes, she has outlined quite a few things. she has said we need to find a way of living with this virus and the way out is going to be slow and it is going to be fazed. she said that we can't return to the way life was before coronavirus. but she has acknowledged that we can stay incomplete lockdown indefinitely. she acknowledged that lockdown also brings about damaging consequences to mental health and also to the economy. and she said that this is a framework and it's not going to be timed —— time to relax restrictions any time soon. social distancing and limiting our contacts with others will be a fact of life for a long time to come, certainly until treatments and ultimately a vaccine offer different solutions. so that means possibly for the rest

of this year and maybe even beyond. and that's why talk of lifting the lockdown, as if it's a flick of a switch moment, is misguided. 0ur steps, when we take them, will need to be careful, gradual, incremental, and probably quite small to start with. she has talked about baby steps. possibly we will see different parts of the economy and different parts of the economy and different parts of the economy and different parts of the country easing restrictions at different times. now this is going to have a huge impact on how schools go back and how businesses go back. but we're likely to hear a bit more about that a bit further down the road. she has also mentioned large gatherings. she says we are not likely to have large gatherings for a long time. places like pubs and restaurants may not open again for some time. see also made the point that if we do ease restrictions and the virus does

start to come back, these restrictions may have to go back in place at very short notice. alexander mackenzie, thank you. let's speak to our chief political correspondent, vicki young, at westminster. it's really striking hearing all of that from nicola sturgeon, even though she is saying don't expect anything to change swiftly, she is putting it out there, she is addressing the topic? yeah, what is fascinating is that the four nations of the united kingdom have been working together on all of this. but when it comes to communication there have been some differences. i think nicola sturgeon standing there saying she wants to have a grown—up conversation with people is inevitably going to put pressure on the uk government, because they are publicly very much sticking to the stay—at—home message. they don't wa nt to stay—at—home message. they don't want to delete that in any way. they are very worried, as everybody is, about the second wave of infections. nicola sturgeon standing there and saying that in giving some more detail is going to add to the pressure. that pressure has been coming from within government as well. some cabinet ministers have said more needs to be done. some conservative mps saying that you

have to give people some hope. you have to give people some hope. you have to give businesses some hope that there is light at the end of the tunnel. but you also have to prepare people for what is going to come. the fact that things are not going to go back to normal. 0n come. the fact that things are not going to go back to normal. on a practical level if you are looking at schools go back, and nicola sturgeon spoke about this, maybe having to reconfigure classrooms because all children cannot go in the same classroom at the same time. those kind of things will need to be planned for. yes, definitely adding pressure to the ministers here in london to say more publicly. and of course in the end, yes, following scientific advice is one thing. but it can't just scientific advice is one thing. but it can'tjust be a scientific decision. this will ultimately be a very balanced and complex political decision. vicki young. government borrowing could jump to its highest level in peacetime history because of the coronavirus lockdown. 0ur economics correspondent andy verity has been looking at the figures, from the office for national statistics. andy, we knew of course the government would have to borrow a lot. but this is the first time we

have been looking at strong numbers here? well, that's right. we did have what we call a scenario from the office for budget responsibility, the official independent forecaster, forecast that the amount the government needed to borrow to plug this huge and widening gap between the money gets in on taxes, and the money it is spending, would be about five times what they predicted just before the budget last month. so now we see the actual concrete numbers. this is the debt management office saying in the next few months this is the money we are going to have to borrow. they revealed that in april alone the government had to borrow £45 billion. that's rather more than we spend on police and safety, more than we spend on primary schools, for example. in may tojuly they will have to borrow £180 billion. 0ver will have to borrow £180 billion. over the course of four months they will end up borrowing £225 billion. that is a mind—boggling sum of money to borrow in such a short space of

time. about a quarter of £1 trillion, about an eighth of the value of the entire economy. that's if the lockdown only lasts as long as predicted. if it goes on for six months the resolution foundation predict it could be half £1 trillion. a £500 billion that the public sector has to borrow. andy verity. thank you. one of the nurses who was thanked by the prime minister for looking after him in intensive care, has said borisjohnson wasjust another patient the team was trying to do their best for. jenny mcgee, who's from invercargill in new zealand, has been speaking about the huge number of messages she's received since being namechecked by mrjohnson, including some from her own prime minister, jacinda ardern. jenny mcgee has been talking to tv new zealand: there was a lot of media interest about him being in hospital. to be honest, that probably was the toughest thing of the lot. as a unit, he was just another patient we were trying

to do our best for, so it was business as usual. see you weren't even a little bit nervous? no, i honestly don't think i was. when i got in the car after work each night, and i could hear things about borisjohnson on the news, that was very surreal because i thought, wow, i've just been looking after him. but i really wasn't fazed by looking after borisjohnson. and what about in terms of icu, do you think they lowered the bar just because of who he is? no, everyone — we take it very seriously when people come into intensive care. these patients who come in to us, it's a very scary thing for them. so we don't take it lightly. and he absolutely needed to be there. talk to us about how he found out you werejenny from new zealand? we just chatted away and it naturally came up. yeah, he was interested in where i came from, what my story was. we spent a lot of time together.

yeah, we talked away about new zealand. you have been lauded notjust by britain's prime minister, but also new zealand prime minister, jacinda ardern. what went through your mind? so, on the night it all happened i actually had to turn my phone off because it was just so overwhelming. and when i turned my phone back on in the morning, people were like, "jenny, you need to look at your facebook." i was being called a snob for not responding to jacinda ardern! but it's very surreal to have a message from jacinda. she's a hero of mine. i think she's amazing. and she just said how proud she was of me, and that the the country was so proud. it's so heart—warming and something i will never forget. did you respond to the prime minister? yes, i responded and she messaged back immediately. a little bit of banter, which was again surreal. a couple of emojis.

so, yeah, just a very, very surreal experience. what are the biggest challenges or issues that nurses are facing today? right now in the pandemic? it is so tough out there at the moment. we are being asked to look after more patients than we normally do. and it's tough. these patients are quite complex when they come in. covid's notjust affecting the lungs, it's affecting many systems in the body. so they're complex, very, very unwell patients that are coming through. we're overwhelmed by patients. we're just doing our best to save as many lives as we can. the intensive care nurse, jenny mcgee. our top story this lunchtime... the first human trials in the uk for a coronavirus vaccine are expected to get under way at oxford university today. but the government's

chief medical adviser has warned it's highly unlikely a vaccine will be available this year. coming up — children in need and comic relief come together for the first time for the big night in, to raise money for people most affected by the coronavirus outbreak. coming up on bbc news... premier league matches could be shown on free to air television once the season resumes — most likely behind closed doors — after talks with the government. eu leaders will meet — virtually — in the next hour to discuss the bloc‘s response to the pandemic, and there's expected to be bitter division over the huge aid package being set up to help economies recover. there's been criticism of the eu's handling of the crisis, particularly from italy, the worst affected country. 0ur rome correspondent mark lowen reports. italy has lived through hell. the first in europe to fall to the virus, the first to call for help.

but in its hour of greatest need, italy says it was abandoned by an eu that hoarded safety equipment, closed borders, failed to come together as one. germany did eventually airlift italian patients and sent in supplies, but others, like russia, were louder, dispatching aid and medics here — seizing the chance to fill the vacuum. it even prompted a mea culpa from the head of the european commission. too many were not there on time when italy needed a helping hand at the very beginning, and yes, for that, it is right that europe as a whole offers a heartfelt apology. in 1957 the treaty of rome was signed right here inside this building establishing the european economic community — the forerunner of the european union — by its six founding members, one of which was italy. this country has always been proud at being at the heart of the european idea, and now many here feel let down

by the project it helped to form. the crisis in relations has played into the hands of the extreme right. some of its members making a public display of hostility, feeding anti—european sentiment, now at its highest ever here. but italy's hard right leader says europe made italians fall out of love with it. translation: what provokes anti—european feeling is the eu's inadequacy to respond, or the idea the eu gives of italy as a beggar needing to be helped, wasting its money. in the bookshops reopened this week, italy's historical ties with europe are on show, but as are its current battles too, with a disease that has shaken the roots of european cooperation. i was pro—european and i have changed my mind. i don't believe any more in the union because i don't think there is solidarity. we felt betrayed. i feel european so i hope everything will change.

this country has fought many battles in its long history, but now one with its allies to help it emerge, recover, rise up again. mark lowen, bbc news, rome. our correspondent, gavin lee, is in brussels. what might this gathering achieve, gavin? welcome in 40 minutes, 27 eu leaders plus the head of the european commission behind me and the council will log onto their video conference summit. they are calling at the road map to recovery summit. two fairly straight forward, they will digitally sign it off after an hour or two. one is something finance ministers have spent 18 hours on, a huge package, 540 billion euros, about £470 billion, a recovery package for a short term for workers and businesses, for governments, that's higher than the gdp for example for

poland and that pretty much the sign off. a road mac is also a physical thing, a guidance for countries on how to step—by—step get out of the lockdown and things like making sure that i see you unit beds are low enough to cope with what is expected to bea enough to cope with what is expected to be a second spike, but the big issueis to be a second spike, but the big issue is the idea of helping italy and spain as we heard from that piece financially in the long term. an idea of a mutual debt sharing programme, the northern european countries very, well, backing away from that now for two weeks. we expect, we've had a letterfrom from that now for two weeks. we expect, we've had a letter from the president of the european council saying they will look to analyse this further, so i expect there will bea this further, so i expect there will be a second emergency summit after whatever happens today. gavin lee, thank you. president trump has played down the risk of a second wave of the virus in the us, as some states start to lift their restrictions. mr trump told a white house briefing that the country had flattened the curve, and the disease might not come back at all. he was contradicted by his top adviser on infectious diseases, anthony fauci — who said there is no doubt the virus

will return, but the country will be better prepared. as muslims prepare to begin the holy month of ramadan, some doctors are expressing concern that the official advice about social distancing isn't reaching many in the community. our religion editor martin bashir has been speaking to one gp in greater manchester, to hear her views about fasting, faith, and whether public health messages are cutting through. with afternoon surgery over, dr siema iqbal is on the school run. she and her husband are key workers, and at the start of ramadan she says she's concerned about whether the government's message on the coronavirus is getting through. i don't understand how it would get through to the muslim community. a lot of the messaging coming out from the government is in english. it's on radio stations and on tv channels that they may not necessarily be listening to or watching. even the letters that we send out advising patients

to shield themselves, they are all in english. these are real specific challenges that this community in particular is facing. 46% of that this community in particular is facing. 4696 of the muslim community lives in the 10% of the most deprived parts of the uk. that surely plays a part. we also have increasing rates of poverty, ill—health, and we have a lot of the community doing more of the precarious roles. they may be working as cleaners, bus drivers, front line workers. a promotional video prepares british muslims for ramadan during the pandemic. no prayers at the mosque. and without communal meals, iftars, like this one held in london last year, that break the daily fast. how significant is the gathering of muslims together at that time? we find that actually people's perception of muslims in this

country has improved through simply coming together to have a meal. for us, seeing the many thousands of stories we've heard from people who have come to events and have left feeling more optimistic, feeling a sense of belonging, it's incredibly difficult to accept the fact that we will not be able to reach out to those in the same way. but the challenges of ramadan this year may yet present an opportunity. i'm always apprehensive about fasting. will i be able to get through the day? how angry will i get when i'm hungry? you know, how much am i going to shout at the children? i think the pandemic has actually brought me closer to religion and made me more spiritual. i can't imagine how awful it must be to do iftar on your own. but i think it will bring us back to the true essence of fasting. martin bashir, bbc news. people living in care homes are among the most

vulnerable to the virus, and the staff looking after them are doing their best to keep the illness at bay. our correspondent ben moore has been to one home on the isle of wight, where staff have moved in with the residents — to try to keep everyone safe. this isn't the sort of accommodation you'd expect to find in a care home. you all right? yeah, i had a good sleep. good. morning! but these tents are for the care staff, who now call this home. i decided to completely lock the home down by asking the staff to move in, so no one in, no one out, at all. if i didn't lock down the home, then it would literally be a case of when coronavirus comes into the care home. that would be absolutely devastating. right...

so staff at the victoria house care home on the isle of wight have put their lives on hold to protect the most vulnerable in their care. i've left my family, i've lived with my grandparents, my parents and my brother. i didn't want any of the virus here at all, you know, the oldest resident here is 103. i love them all to bits and wouldn't want it here at all. i have left my husband at home to keep this house safe. we are happy to stay here and follow this through until it's safe to go out again. it wasn't an easy decision to make, to decide to lock down and to leave all our commitments, our partners, our families, our children, at home, to come and live in a care home. to live in these facilities that we share with our residents — it's incredibly challenging and very difficult.

this is a small care home — just 20 residents, all aged between 82 and 103. i feel for them. giving up all their home comforts. saying thanks is not enough. i think it's a wonderful idea. it's lovely to see it from my window. and you've been round to see the tents, haven't you? yes, i have, they're lovely. they've been really kind and caring and more concerned to ensure that we are safe and we have everything that we need as well. this is one place where staff and residents are certainly all in it together. they're completely giving up absolutely everything, they're giving up their families, their children, they're giving up their down time to come and give their all to victoria house, and for that i am so grateful. ben moore with that report.

tonight, children in need and comic relief come together for the first time, to raise money for people most affected by the outbreak. the big night in features celebrities including lenny henry, peter kay and dawn french, and it's all on bbc one this evening. here's our entertainment correspondent, lizo mzimba. each year, children in need and comic relief... £63 million! ..raise huge amounts for good causes. tonight's event will be put together a little differently, with many well—known names performing sketches from their homes. # the lord is my shepherd # i shall not want!# last night, i had the 1st meeting of the dibley parish council, conducted via an app called zoom! and i have to tell you, it was the best parish council meeting i have ever had! largely because none of the other

councillors know how to get onto zoom. for one night only, children in need and comic relief get together to celebrate our nation's kindness and resolve with an evening of star—studded entertainment to lift our spirits! it has all come together in just a few weeks, in less than straightforward circumstances. we are calling it the big night in. children in need and red nose day usually take months of meetings and planning. it's only been challenging that we have had to do it quickly. what has made it so extraordinary is the absolute passion of people to help. i think it is harder because it is less time, but easier because everyone is so aware of how much difference the money is going to make. the money raised will go to organisations like fareshare, which sources surplus food and redistributes it to community groups, so that vulnerable people can receive good quality meals. ijust thought i would show you some of the donations that we have

received today. we have got all these pallets here that have come from suppliers' donations. these were all public donations. and it's notjust celebrities getting involved. peter kay will be recreating his famous amarillo video, using clips sent in by key workers from around the uk. lizo mzimba, bbc news. the duke and duchess of cambridge's son louis has been photographed to mark his second birthday — making a rainbow tribute poster. a series of images has been released by the family to mark the occasion, including pictures of the prince showing off his brightly painted hands. children across the uk have been creating rainbow pictures as a symbol of hope during the lockdown. time for a look at the weather. here's ben rich. thank you. i think they are the only rainbows we are going to see today

because there isn't