hello and welcome to the latest. on today's programme we hearfrom frontline health workers on their fears of a second wave of covid—19 infections plus how a team of scientists is trying to work out why coronavirus affects different people in such extreme ways. you can always keep up—to—date with the latest information about the pandemic on oui’ information about the pandemic on our website. first, the world health organization has want of a second peak of coronavirus cases. if lockdown restrictions around the world a re lifted lockdown restrictions around the world are lifted too soon. the threat of a pocket —— possible second wave puts healthcare workers underfurther second wave puts healthcare workers under further pressure in second wave puts healthcare workers underfurther pressure in many countries. the bbc has been given

unprecedented access to one hospital in the community in the heart of london who have been coping with the pandemic to hear their fears about the possibility of a second wave. the bbc‘s clive myrie reports in east london. it is in times of crisis we find out who we really are. i felt roque and on many occasion and i think a lot of my collea g u es occasion and i think a lot of my colleagues have. when souls are laid bare. in this time of coronavirus, this hospital and one community reflect on these troubled times. coming upforairto reflect on these troubled times. coming up for air to reveal their souls to us. we saw the fragility of

life. i am going to take out your tube now. we saw strength. how does that feel? and all the while, one fear looms, another peak of infections to rival the first. while many patients inhabit ventilated worlds, the doctors and nurses charged with bringing them back to life inhabit the real world where time moves too quickly. is this cruel disease eats away at human lungs with frightening speed. and we just do a couple more? but the medical staff including consultant pj medical staff including consultant pj have their own nightmares. are you expecting a second wave? yes. i

have to say yes because i think once the lockdown is relaxed, people of course i going to have more contact with each other so that is the way this is going to spread. but if the lockdown completely disappears, then i suspect the cases willjust rapidly rise again. then, as our interview ends, he is called away. his two minutes turn to several agonising hours. we had permission from the patients and their families to film. this man's vital signs have worsened. he isjust 55. the professionalism of the team is dating, years of experience gathered around this bed is the duality of time, the drifting oblivious patient under rush to save his life, merging toa under rush to save his life, merging

to a tableau for our times. how concerned are you? extremely concerned. especially at this late stage. so there is a final role of the dice. this is a last resort, maybe you can force oxygen into his body, it is all you can do. his lungs are getting worse. are you preparing to talk to his family? yes, that's right. sister becky smith, her presence on the covid ward for absent residue —— relatives. we will make a decision

as to whether it is appropriate to continue what we're doing. imagine the stress for the team multiplied every day for weeks. now you understand what the peak of the pandemic was like. sister carlene kelly bore witness to those dark days. i felt broken on many occasion andi days. i felt broken on many occasion and i think a lot of my colleagues have, it consumes you. it is what you think about when you go to bed, when you wake up, you are preparing for your next shift. you are relieved that the previous shift is over, you are sad. it is a huge emotional burden. it is the time of oui’ emotional burden. it is the time of our lives that we will never, ever forget. the peak almost broke minds and according to consultant nick bunker, almost broke the royal london. in normal times bunker, almost broke the royal london. in normaltimes we manage

about 44 patients. at the peak we we re about 44 patients. at the peak we were managing just shy of 90 patients. almost double. almost double. we were 20 beds away from being overrun for. we were keeping people alive. that is what our goal of care was, keep as many people alive as long as we can until we can get back to being able to deliver the quality of care that we always aspire to deliver. sometimes it is ha rd to aspire to deliver. sometimes it is hard to find light in the darkness. but you are about to witness what medicine can do. this is one of the defining moments in and intensive ca re defining moments in and intensive care unit. when a patient‘s ventilator tube is removed. it is a procedure full of expectation and dread. will it work? he is grimacing as the tube inches up his throat.

and finally leaves his chest. everything's ok, you are at the royal london hospital. the heavy breathing of a man given a second chance. it is a victory for everyone, as i said, he is still not out of the woods but he is doing good and we are pleased to where he has come to. there are other defeats. sadly, that evening, krishna died. another soul, lost. as scientists and governments raced to stop a second outbreak, one of the key questions being asked by medics is why some people get more severe symptoms than others. it seems the answers might life in research being carried out by

scientists, clinicians and volu nteers scientists, clinicians and volunteers in cambridge. richard westcott. why does covid—i9 put some people like george gilbert here in hospital, yet others get no symptoms at all? he has volunteered to help find out because part of the answer might lie in his blood. find out because part of the answer might lie in his bloodlj find out because part of the answer might lie in his blood. i didn't think there was any left. once it is sealed up, the bloods passed a volunteer, his manager had to go on hold because the virus big he has set upa hold because the virus big he has set up a team that every day carries covid samples to be analysed. it is quite an odd way to interview someone. how did you get involved in this? i would normally be working in a lab of people with rare lung disease so it is frustrating because i can't do that so i e—mailed my collea g u es i can't do that so i e—mailed my colleagues and asked how could i get involved, how could i help. samples are taken to a brand—new lab just around the count corner in the

biomedical campus. your blood contains cells that play a key role in fighting off the coronavirus. some of them make antibodies, others directly kill infected cells, but do analyse them, first you have to separate them off. allan at the very bottom, the red ones are the heaviest and go to the bottom of the tube and at the top, the plasma, the solution your blood flows in normally. then we are looking at these white small band, that is the white blood cells fighting off the infection. then it gets more complex. there are lots more types of white blood cells or playing different roles. so next door, a machine uses lasers to count how many you have got of each key type. it can then separate millions of them off for more tests. incredibly, each blob here is a droplet of salty water with one cell inside. 260 addenbrookes patients and staff are giving their blood for this

research. some got very sick, some didn't. the key question for scientists, can you see the difference in their blood? we have found a number of severe abnormalities in patients with advanced covid disease and some of those point very clearly to potential therapeutics that might impact on that disease. what we are hoping is that when people develop symptoms that make them suspect they might have covid and get their very first test, when tests become more readily available, at that point we might be able to protect ad predict who might go want to get severe disease. by understanding the science of the disease, it is easier to find drugs to fight it. that is it for now, you can follow me on twitter or head to the bbc news site for the latest information. take you so much for watching. —— thank you. well, friday was a very warm day across the uk.

in fact, the hot spot was scotland. temperatures got up to 28 degrees. and saturday, in most parts of the uk, will be every bit as warm, at least the low to mid 20s in most major towns and cities. it's been so reliable during the lockdown that the spring has ended up being the sunniest one on record. so, this has been confirmed by the met office. now, high pressure is in charge of the weather across a large chunk of europe. it's centred across scandinavia and it's clearing the skies across the uk, ireland, much of western and central europe. these are the 6am temperatures. a little fresh in parts of east anglia. maybe in the rural spots, temperatures could be around 6 degrees, but elsewhere, not quite as nippy. very quickly, the temperatures will rocket during the course of the morning and into the afternoon. let's take a closer look. so, on friday, we had temperatures up to around about 28 in some parts of western scotland. probably not quite so hot on saturday, more like the low to mid 20s.

very warm there in glasgow at 2a celsius. we'll match that in liverpool, in birmingham, and probably the hot spot will be somewhere in the south of england. temperatures will get up to around 25 celsius. now, the sun will be very strong as well. you can see high uv levels pretty much right across the country, so take note if you're planning to enjoy that fine weather outdoors. saturday night's looking absolutely fine, and then sunday, we do it all over again. the winds are light, the skies are clear, the temperatures are going to rise. in fact, in one or two spots, it could reach around 26 or 27 celsius, so a hot day on the way, especially across western parts of england, on sunday. and over the next few days — so this is including the weekend and into next week — that warm plume of air from the southern climes continues to spread across the uk, as far north as scandinavia, even pushing to the arctic circle. so those temperatures are expected to affect peak across the south

of the uk come tuesday. we could see temperatures getting up to around 28 degrees celsius. but after that, a big change on the way. look at that — back into the teens by the time we get to the weekend. in fact, next weekend, we're expecting colder air coming in from the north. that's it for me. goodbye.

this is bbc news. welcome if you're watching here in the uk, on pbs in america or around the globe. i'm lewis vaughan jones. our top stories: live in the city of minneapolis. right and demonstrations continue even though there is a curfew in place. the police officer derek chauvin has been arrested and charged with third—degree murder. this was a scene in boston where hundreds of activists and police have clashed over the death of george floyd. president trump offers his sympathy to the family of the victim and calls

on protesters to obey the law.