this is bbc news with the latest headlines for viewers in the uk and around the world. thousands of people in the uk are injected against covid—19 on the first day of a mass immunisation programme — the first for a fully tested vaccine. the mammoth operation to distribute vaccines across the globe, and the obstacles it's already facing. in yet another final attempt to unlock post—brexit trade talks — borisjohnson goes to brussels for dinner on wednesday with the european commission president. why did the players walk off the pitch during a champions league game in paris? we'll have all the details.

hello and welcome if you're watching in the uk or around the world — i'm tim willcox. thousands of vaccinations have taken place on the first day of a mass coronavirus inoculation programme, after britain became the first nation in the world to administer a fully tested jab. a 90—year—old woman was the first to receive the pfizer—biontech shot, which manufacturers say it is up to 95% effective. the government has ordered a0 million doses with 800,000 in the first batch. 0ur health editor hugh pym reports. an early morning hospital appointment. at first glance, nothing out of the ordinary. but this was unlike anything before. margaret, aged 90, was the very first patient to receive the newly—approved coronavirus vaccine. applause there was a well deserved round of applause, and intense

interest amongst media and health officials at this hospital vaccination clinic in coventry. she seemed to take it all in her stride. so, margaret, first of all, tell us, how was it for you? it was fine, it was fine. i wasn't nervous at all. it was really good, yeah. and what do you say to those who might be having second thoughts about having this vaccine? well, i say go for it, go for it, because it's free, and it's the best thing that's ever happened... ..at the moment. so, do please go for it. that's what i say, you know? if i can do it, well, so can you. the matron who administered the historicjab said this significance only sunk in afterwards. i do this all the time. i've done hundreds of vaccinations, but never with such interest, and people, like, wanting to know what's going on and wanting

to actually witness it, so it was really surreal. it's a world first, it represents extraordinary progress by science, but for the nhs, this is a huge achievement, turning research into reality. around the uk, there were similar stories. in glasgow, the vaccine was delivered to the sec centre, with nhs staff among the first to receive the jabs. it's really exciting, it's lovely. you feel like you're a wee bit of history in the making. it's really lovely. in belfast, health staff queued to get theirjabs. the policy is for those doing the vaccinations to be vaccinated first. the health service in general has struggled throughout the fight with covid—19, so it feels like a momentous day. very privileged. at this vaccine centre in cardiff, one of seven in wales, more than 200 people have been booked in every day till friday. we do need people to be patient

for that bit longer. let's get through to the spring. as we work through to the spring, we'll be vaccinating as many people as we can. it's a good day for the whole country. the prime minister, on a visit to a london vaccination centre, wanted to rein in people's expectations. i urge people to contain their impatience. it's a very exciting moment but there's still a lot of work to be done and a lot of discipline to be maintained. the head of nhs england was urging people not to turn up without appointments. wait to hearfrom the nhs. we will make contact with you. the vaccine is being made available to us from the manufacturers on a phased basis, so the bulk of the vaccination is going to be injanuary, february, march and april. the priority groups now include the over—80s. hari and ranjan, who spoke to us yesterday, had their jabs

together in newcastle, with badges to prove it. applause margaret certainly won't forget her vaccination, nor will nhs staff on a dramatic and momentous day which they can only hope marks a turning point. hugh pym, bbc news, coventry. president—electjoe biden has introduced the health team that will lead his administration's fight against the covid—i9 pandemic. he announced a three point plan that will be carried out in his first 100 days in office. the first is mask wearing. itch will start with my assigned order on day one to required masks where i can under the law. like federal buildings, interstate travel on planes, and buses. at the same time donald trump was holding an event to outline america's vaccine roll—out. however, both of the companies behind the top two vaccine candidates declined to attend. pfizer is one of them — its vaccine, developed with biontech is expected to be given emergency approval by us regulators

on thursday and president trump says his administration is on their case. we arejust we are just days away from authorisation from the fda and we are pushing them hard. at which point we will immediately begin mass distribution. there are more than a0 vaccines undergoing human trials around the world. david chapman reports. the vaccine deployed today marks a turning point for the uk, but when will it start to reach the rest of the world, along with all the others that are being developed ? a huge global operation is getting under way. doses of the pfizer/biontech vaccine, which requires extreme cold, are ready to be dispatched as soon as other countries follow the uk in giving approval.

but at the moment, supply can't possibly meet demand. the manufacturing process is complicated, and industry analysts say that production is encountering more hurdles than expected. it's incredibly hard to produce a vaccine. it's like cooking the same soup again and again, night after night, and it has to taste exactly the same. it's very difficult to do at scale. so we will see hurdles and i think the production figures, the big figures that are floating around, they are on the optimistic side. there's no doubt about that. rolling out the vaccines on a global scale is a daunting challenge. the global population stands at 7.8 billion. not everyone needs to be vaccinated to suppress the pandemic, maybe 70% to achieve what's called herd immunity. but that still leaves 5.a billion people, and three leading manufacturers of vaccines say that they hope during the course of the next year to produce enough doses for 2.6 billion people,

so that still leaves more than half the planet waiting for a vaccine, probably in 2022 or even the year after. and when the poorest nations do get the vaccines, there will be the immense task of distribution. this was the journey for an ebola vaccine. there are initiatives to help developing countries, but they're not at the front of the queue. it feels like there is a lot of vaccine nationalism happening. so, that's rich states buying up the vaccines for themselves. now, the issue there is not who gets it, because i think the vaccine will become available to lower and middle—income countries in particular, but when — that's the big problem. meanwhile, russia has started using its own vaccine. but many are wary of it because safety trials are still under way. and china is also producing vaccines, but there are questions about whether enough testing has been carried out. getting this far is the result of some brilliant research conducted under immense pressure.

the job now is to get it out to the billions who are waiting. david shukman, bbc news. despite the great advances on vaccines, a lot of questions remain. for example, we don't how long vaccines will protect people, or whether they stop the virus being transmitted to others. to help us is immunologist dr gigi gromvall, who is a senior scholar atjohns hopkins center for health security. thanks forjoining us on bbc news. well, a wonderful day for the people of britain, it seems to be a wonderful day for other people around the world quite soon as well in terms of the first vaccinations but there is still a what we don't know isn't there? just talk us through that. yes, we just don't know exactly how long protection is going to last like you just said, and we don't know if people are able to transmit the virus to others

after they've been vaccinated. we don't know if they have sterile rising immunity. they didn't look to see if people were perhaps asymptomatic and spending the virus. that is a data gap we need to fill over the coming months. although i think the oxford virus with astrazeneca is explained that an trials or when to start in a few weeks' time about that because there is some indication that it might stop asymptomatic transmission. would that be the sort of holy grail really because once you have that, you are stopping the spread of the infection but again maybe we don't know for how long. right, we are going to be in a situation for a while where people are going to need to wear masks and do social distancing because we just don't have everybody vaccinated but for the individual it's going to be really important to know if you are protected and you are able to stop transmission if you were to encounter the virus. so, transmission if you were to encounterthe virus. so, i transmission if you were to encounter the virus. so, i think we will get to know that in the next

couple of months and i am sure that will be fantastic for the people who get vaccinated. now where you are, pfizer hasn't yet been approved by the regulator. but it is your feeling that it will be rolled up quite soon because you have the vast majority of the doses there, don't you? right so the sages definitely set. the fda, they released their report today their findings about the vaccine and everything looks as good as the data that you have seen. so, there will be a committee meeting, an advisory committee meeting, an advisory committee meeting in a couple of days and they will make a recommendation to the fda commissioner who will decide whether or not this will go to full approval. and how do countries persuade people to have these vaccines? it was interesting in the uk today. a lot of people at the vaccine were out three and came from the generation of the second world war who

the generation of the second world warwho said, the generation of the second world war who said, "why not take it if it can save our lives? " war who said, "why not take it if it can save our lives?" but of course there are the anti—vaxxer movements. how do you think governments should address those movements? first of all they have to make sure that they are providing as much information as they can and to be seen as a trusted source of information because there is going to be a lot of misinformation out there that are going to give people half—truths or make people fearful about the vaccine. so, being upfront about what is the safety data and on the results so far is a big part of that. and also people should be prepared that this is a vaccine that is going to for many people, they are going to know they got a vaccine. so, there's some side effects. some people are going to have some arm soreness, they're going to have headaches. but the vaccine is so proven to be so effective so far. so, you know,

people just need to be aware that they are going to have some side effects. in a word as an academic, and this is a safe, is it and you would take it? i cannot wait to take this vaccine. 0k, thank you. dr gigi gromvall, thank you very much indeed for joining gromvall, thank you very much indeed forjoining us on bbc news. stay with us on bbc news, still to come — why did the players walk off the pitch in paris saint—germain‘s champions league game? john lennon was shot at the entrance to the dakota building in the centre of new york. there's been a crowd here standing in more or less silent vigil, and the flowers have been piling up. the iath cease—fire of this war ended at the walls of the old city of dubrovnik. this morning, witnesses said shells were landing every 20 seconds. people are celebrating

the passing of a man they hold responsible for hundreds of deaths and oppression. elsewhere, people have been gathering tomorrow and his passing. to mourn his imelda marcos, the widow of the former president of the philippines, has gone on trial in manila. she's facing seven charges of tax evasion, estimated at £120 million. she's pleaded not guilty. the prince and princess of wales are to separate. a statement from buckingham palace said the decision had been reached amicably. this is bbc news. the latest headlines. thousands of people in the uk are injected against covid—i9 on the first day of a mass vaccination programme. 90—year—old margaret keenan is the first to get the jab. and us president—electjoe biden pledges mass vaccinations across the united states in his first 100 days in office.

1a leaders of pro—democracy demonstrations in thailand have been charged with insulting king maha vajiralongkorn. critics say it shows the military—backed authorities are once again using the country's strict lese—majeste law — to clamp down on dissent. for months, the mainly youthful protesters have been demanding that the military—backed prime minister, prayut chan—o—cha, stand down, and that the king's role in politics be limited. i'm joined by akkarasorn 0pilan. she's a 16—year—old student who's been taking part in pro—democracy protests. she is the co—founder of choose change, an online platform designed to engage young thais in social and political issues. thank you very much forjoining us. i think you were out demonstrating yesterday as well, and other people have been arrested. you are 16, just

tell us why are you involved in these protests? what are you looking for? so as a 16-year-old, i would just like to initially point out that i am not the only 16—year—old, iam not that i am not the only 16—year—old, i am not the only teenager here in this movement. if we look at the protest we can see more than thousands and hundreds of thousands of young teenagers like me out on the street to protest and the first main reason is we now know that politics interferes with every single aspect of our lives and if the older generations who are sitting in the parliament right now are not going to change, their future is not at stake but it is our futures that are at stake and therefore if we cannot make changes in the parliament as youths, then we can make change out in the streets. 0k, can make change out in the streets. ok, but as you know, thailand is divided. you are protesting but you've got people defending the status quo taking part in big demonstrations as well. so, is this just a generational divide do you

think in thailand? it's as simple as that, it is young versus old?|j think that, it is young versus old?” think it's definitely a generational difference, a generational gap because we can see that in the parliament or in the military or in anywhere that governs the body of the country, they are all how do you say... we have a very big generation gap between us protesters and them but ultimately it boils down to the change of id algae, the lese—majeste are, the passing of the previous king in the current prime minister, we can definitely say it is a generation gap, different in the way we view the monarchy or how we view democracy but it boils down to change or whether or not... sorry to interrupt but do your parents or do your grandparents share your views? yes, my grandparents and my parents are very supportive of me and the democratic movement right now. but it just seems that the powers that

be at the moment are determined to ride this one out. so, what more can you do? i think there was nine arrests today, three of whom had been arrested before. where is this realistically going to lead? if you could, just explain for a review is the significance of the three fingered salute that so many of the protesters are using at the moment. so, the three fingered salute here, it symbolises our hope for the fight for this democracy and we have three demands. so, the first one is for the prime minister to resign. the second one is for the police to stop harassing the people. we have another third demand, which is in terms of the lese—majeste law. in reality we have much more demands than that but these are the three we re than that but these are the three were focusing on the most, and also the change. we need a new constitution. that is quite a long list, isn't it? thank you very much

for joining list, isn't it? thank you very much forjoining us here on bbc news. boris johnson will travel to brussels on wedneday to have dinner with the president of the european commission, ursula von der leyen, to try to unlock a post—brexit trade deal. negotiations remain stuck with only weeks to go before the transition period ends at the end of december. the politicians hope that meeting in person will find a solution. 0ur deputy political editor vicki young has more. reporter: will there be a deal, prime minister? trade talks have run into trouble, and borisjohnson will soon need to take some difficult decisions. everyone is waiting to see if there is a way through. i think the situation at the moment is very tricky. 0urfriends havejust got to understand that the uk has left the eu in order to be able to exercise democratic control over the way we do things, and then there is also the issue of fisheries, where we are a long way apart still, but hope springs eternal.

there has been progress in another very tricky area. to avoid checks along the irish border, northern ireland will continue to follow some eu rules. but that means inspections on certain goods entering northern ireland from the rest of the uk. businesses there have been worried about extra paperwork and the impact on food and medicine supplies. how do you start to unpeel the complexity that is northern ireland and not create any instability? so, i think if they've got some sort of solution today, albeit late, we would welcome it and we would be pleased, and we hope that with the detail coming out, they have listened to our concerns. this has been a hugely complicated and controversial issue where economic considerations have had to be seen in the context of a delicate peace process. positives have been difficult to find in recent days when it comes to brexit negotiations,

but this is most certainly a very important positive for the island of ireland as a whole because what this does now is it provides the guarantees that ireland's place in the single market and the issues around the border are now all settled. hopefully, this is a signal that the british government is in deal—making mood. some see today's agreement as a positive sign for the broader trade talks, but don't forget those arrangements in northern ireland will apply whether there is a deal or not, and eu sources say their chief negotiator, michel barnier, has told european ministers we are now tilting towards no deal. and while politicians talk, the uncertainty affects businesses everywhere. the manager of this sawmill in somerset says he is ready to adapt. we have to be as positive as we possibly can about it and move forward. we employ three, four people and a couple of part—timers, and having to let people go is the worst thing for me,

so my biggest fear is having to let staff members go if there are price increases and we become less efficient and if we go into recession. tomorrow, boris johnson heads to brussels for dinner with the president of the european commission, a last chance to find a breakthrough and a trade deal that both sides can sign up to. vicki young, bbc news, westminster. let's get some of the day's other news. the us supreme court has rejected a last—minute effort by president trump's allies to overturn the election results in pennsylvania. the lawsuit argued that the state's general assembly exceeded its power by allowing universal mail—in voting. the justices offered no reasoning in their order, and there were no noted dissents. the case was just one of many brought by mr trump's supporters as they try to reverse joe biden‘s election victories in a series of key states. prosecutors in the trial of french ex—president nicolas sarkozy have called for him to be sent to prison. they're seeking a term of four years, of which two would be suspended.

mr sarkozy is accused of trying to bribe a judge in exchange for inside information on an inquiry into his campaign finances. a european champions league football match in france will have to be completed on wednesday, after both teams walked off the pitch, accusing a match official of racism. 1a minutes into the game, players from paris st—germain and istanbul basaksehir refused to continue. basa ksehir accused the romanian fourth official of racist behaviour during an argument with their assistant coach, pierre webo, a former cameroon player. let's get more from our sports reporter, tulsen tollett. just talk us through, extraordinary how both teams are walking off. 40 minutes into the game and all of a sudden the match comes to a halt. the assistant coach of istanbul basaksehir accused the assistant coach of istanbul basa ksehir accused and was the assistant coach of istanbul basaksehir accused and was given a red card by the assistant on the

sideline, the fourth official for something he called out. now, other players came over because they did not like the language which was used, this was something that and u efa used, this was something that and uefa have been trying to stamp out of the game in their say no to racism campaign and we normally see this in situations with the fans. now this here is something which is unprecedented, nothing i've ever seen unprecedented, nothing i've ever seen it before, no one has seen it before i don't believe, where a all the players wash off the field. you can see there in the grey, he was remonstrated with the for the official and asking the question which was clear to see on tv which was why he referred to the player is a black player, he was upset with the language that was used in fairness the psg players need to get sunday from this game or manchester united lost in their game to get through to the next round and they drop with the istanbul basaksehir players, there is him on the right there in the middle of the fear of what that fourth official. so the

match will be resuming from the 1ath minute at the park in paris. at 1755 gmt, seems to come out from a simple pressure and president erdogan saying to them to stay strong, he said that he strongly condemns the racist remarks. uefa are going to look at this further and the officials who are being in charge of the match in just officials who are being in charge of the match injust under 2a officials who are being in charge of the match in just under 2a hours' time will be different for officials to those who were in charge of this game here. this will ramble on but paris saint—germain and cribbage are going to go through to the west 16 regardless of this result in the game. tolson toilet, think you very much indeed. —— tolson told it. royal air force has released footage from a flight over the world's biggest iceberg in the south atlantic. the transporter was on a mission to assess the state of the block, which is about 150 kilometres long

and broke off the antarctic in 2017. the pictures reveal multiple cracks and fissures, innumerable icy chunks that have fallen off, and what appear to be tunnels extending under the waterline. for me and the team, bye—bye for 110w. hello there. low pressure will continue to bring more unsettled weather to our shores for the rest of this week and very slowly, those temperatures will be creeping up as we reach the end of the week and into the weekend. now for wednesday, we'll have some showers across eastern areas. some sunshine will develop though behind it is this ridge of high pressure that builds in and then there will be rain pushing tow western areas later on all courtesy of this new frontal system. so we'll start off rather grey, misty, merky conditions with some showery bursts of rain through this morning. they should eventually clear away, it's an improving picture with some sunshine developing though showers holding on across northeastern scotland. later in the day for northern ireland,

western fringes of england, wales and practically into the south west we will see thicker cloud moving in here with outbreaks of rain. temperatures slowly climbing but again it's going to be another chilly day for most, up to 5—7 celsius quite typically. as we head through wednesday night, we will start to see that cloud thickening up across the east as well. it looks like most of the heaviest rain will start to push across wales, the south west england, to the channel islands. elsewhere, we will hold onto quite a bit of cloud, some light and patchy rain and under clearing skies across the north, it will be quite chillier otherwise, less cold than it's been on other nights. on thursday, we are in between weather systems although we have this weather front affecting the northern half of the uk. we've got a slack airflow once again so when‘s will be late rather grey skies for many with some patchy light rain or drizzle, reno little bit heavier across scotland. could see a touch of winteriness over the high grounds. the air is still quite cool with those highs ranging from 5—8 celsius.

but slowly coming up across the south west, 9—10 celsius there for cardiff and for plymouth. as we head on into friday, a more substantial frontal system spreads its way eastwards across the country. this one will bring a bit of a change to the weather, some heavier rain at times will make its way towards the eastern side of the country, winds stronger for a time, and then skies will brighten up so, it's out west where will start to see temperatures lift by the end of friday, 10—11 celsius here. a little bit less cold further east, too. still on the chilly side — with temperatures in single figures. into the weekend, we hold onto a lot of cloud, some rain in northern and western areas. by sunday, we'll see another area of low pressure which will bring windier weather, some milder air, and also outbreaks of rain.

this is bbc world news, the headlines. britain has become the first country to begin a mass coronavirus vaccination programme, with an authorized, fully tested jab. 90 year old margaret keenan, got the first dose of the pfizer biontech jab, outside of the clinical trials. us president—elect, joe biden, aims to get 100 million covid vaccine doses injected into americans in his first 100 days in office. he said that congress would need to push through funding to aid distribution of vaccines. the us supreme court has rejected a last—minute effort by president trump's allies to overturn the election results in pennsylvania. the lawsuit argued that the state's general assembly exceeded its power by allowing universal mail—in voting. the british prime minister and the president