welcome to bbc news. i'm james reynolds. our top stories: protests continue in myanmar as the un calls for the release of leader aung san suu kyi, who's been charged by police, following monday's military coup. essentially, what people here are saying is they do not want to live or work under the military anymore. future—proofing the covid vaccine — how scientists are already working to make sure the new vaccines can be adapted to deal with any new variant. a 22—year—old american who had the world's face and hand transplant talks about his surgery, saying he feels gratefulfor surgery, saying he feels grateful for a second chance at life. three female directors make history by being nominated

for a golden globe awards — that's the first time more than one has been shortlisted in a single year. welcome to our viewers on pbs in america, and around the world. in myanmar, police have filed criminal charges against the civilian leaders who were deposed in a military this week. there's been no word on the whereabouts of either aung san suu kyi or deposed president win myint since monday. the united nations said the charges just "compounded the undermining of the rule of law in myanmar and the democratic process" — and they called for the immediate release of the leaders. for a second day, protesters banged pots and sounded car horns in the country's largest city.

our reporter nyein chan aye filed this report from yangon. pots banging people are showing their frustration and anger against the military coup. it has taken place on monday. this is the second night in a row people in general have been banging pots and pans and using their car horns in protest against the military coup that took place on monday. essentially, what people here are saying is they don't want to live or work under the military any more. singing translation: we only - respect our elected president, and no—one else. if the president wanted the military to take over, then, we would have accepted that, but this coup is not fair so we're expressing our feelings in a peaceful way. we're the voice of the little people. translation: | witnessedl the coups in 1962 and 1988.

we know about what happens under military takeovers, so we have to do this. if we take to the streets, they will shoot us dead. under these circumstances, i support this kind of protest. we want the elected leaders back. translation: people don't accept the coup. i that's why we want to drive them out by doing this. - pots banging on the other hand, the military is taking total control of the country. the military has installed an 11—memberjunta which they say will rule under a state of emergency. singing

the people of yangon have come out here again in less numbers than yesterday to say they want their vote and voice to be heard. singing nyein chan aye, bbc news, yangon. around the world, vaccines are being produced that might help us return to something like normal. here in the uk, more than 10 million doses have already been given. but at the same time, the virus is mutating. so, scientists are turning their attention to how to adapt vaccines to make sure they work against all new variants. astrazeneca and oxford university say they plan to have a next—generation vaccine ready for the autumn. our medical editor, fergus walsh, reports. the scientists at oxford who created the astrazeneca vaccine are continually monitoring how coronavirus is evolving.

the current vaccine is thought to give good protection against new variants, but they're working on tweaking the jab to make it future—proof. the scientist who's leading the research says it's relatively simple to redesign the vaccine. it's not difficult to put a different antigenic insert into the vaccine. so, we don't want to panic and say that we must have a new version of the vaccine now but on the other hand we are getting prepared, so that if it turns out we do need a new version, we will be ready to start using it. it'sjust going to be a sharp scratch, ok? those on the oxford vaccine trials were shown to have 76% protection from a single dose, which lasted three months, rising to 82% protection, with the second shot. you'll be doing swabs every week at home. it's also the first time a covid vaccine has been shown to reduce transmission of coronavirus. those immunised were much less likely to test positive for infection, cutting the risk of them passing the virus on to others.

that's the vaccine, but what about those who have actually had covid 7 they want to know how long they may be protected against subsequent infection. a study involving nearly 20,000 volunteers may provide at least part of the answer. like the other participants, i was asked to send off a few drops of my blood every month to a lab. scientists at uk biobank found that 88% of participants, nearly 9 in 10, who started off with antibodies, still had them six months later. these findings are really good news, because it does suggest that people who have been infected with the virus may have some degree of protection against another infection for some considerable time. and i think what we would really like to know next is, how long does this natural immunity last for beyond six months? scientists think vaccines are likely to offer much stronger protection than natural infection, so a key message is to get immunised, even if you have

already had covid, to boost your immunity and maybe protect others. fergus walsh, bbc news. let's get some of the day's other news. nancy pelosi, the speaker of the us house of representatives from the democratic party, has confirmed there'll be a full vote on thursday about whether to strip a republican representative of her role on two key congressional committees. marjorie taylor greene, from georgia, is accused of encouraging bogus conspiracy theories and making anti—semitic comments online. the us treasury secretary, janet yellen, has called a meeting of top officials that could result in tougher financial market regulation. mass buying by amateur stock traders — many of them active on reddit forums — has led to volatility in some company share prices, including gamestop and amc entertainment. the issue of farmers' protests in india has attracted the attention of international stars and activists, who have criticised

the response of the government. rihanna, greta thunberg, and meena harris, the niece of kamla harris, have all voiced their solidarity against agricultural reforms. officials running this summer's tokyo olympic have set out how they to plan to keep the games safe during the pandemic. athletes will be tested for covid every four days, must wear masks, and will be discouraged from using public transport. those watching won't be allowed to cheer or shout — only to clap. afghanistan's stalled peace process is facing the "high probability of failure" — that's the stark warning coming from the eu's commissioner for crisis management, who's visiting the country. in addition to that, a bipartisan report to the us congress has strongly urged president biden to delay a trump administration plan to pull all us forces out of afghanistan by may 1st. let's get more on this from professor geoffrey corn, an expert in national security

law at south texas college of law. he served in the us army for 21 years and joins me now from houston. professor, what will the biden administration do? i professor, what will the biden administration do?— professor, what will the biden administration do? i think what ou are administration do? i think what you are going _ administration do? i think what you are going to _ administration do? i think what you are going to see _ administration do? i think what you are going to see is - administration do? i think what you are going to see is a - administration do? i think what you are going to see is a very l you are going to see is a very deliberate and cautious assessment of exactly where we are, what the mission is, and what the requirements from the military are to accomplish that mission. i do not think you are going to see anything hasty, and i think the president is going to take serious consideration of this bipartisan recommendation, because i think he seeks to find bipartisan consensus, particularly in the area of foreign policy.— particularly in the area of foreign policy. will he get it? i think the — foreign policy. will he get it? i think the president - foreign policy. will he get it? i think the president is - foreign policy. will he get it? i think the president is very l i think the president is very likely to retain a more robust presence in afghanistan than president trump suggested he would have, following withdrawing all the troops are. i think the president recognises the interest in supporting nato and eu partners. we know this is another key objective for a

foreign policy for him, to reinvigorate the effectiveness of multilateral action and of the lateral security operations. and if the partners are deeply concerned about the precipitous withdrawal, i think that will also be a substantial influence on his decision. afghanistan has been a huge role in us politics since 9/11. is mr biden willing to stake his presidency on it? after all this time, is afghanistan an afterthought? i this time, is afghanistan an afterthought?— afterthought? i certainly do not think— afterthought? i certainly do not think it _ afterthought? i certainly do not think it is _ afterthought? i certainly do not think it is an _ afterthought? i certainly do l not think it is an afterthought stopping here is what i think. i think president biden wants to allow the national security system that he has created around him to do itsjob. that means he is not going to make a rash decision, and impulsive decision. he is certainly not going to make a decision that is going to catch the pentagon off guard and surprise them. he wants to hearfrom his national security advisor is, secretary of state, he wants to give his secretary of defence the opportunity to assess the

situation and come to him with recommendations, and i do not give the recommendations are that it give the recommendations are thatitis give the recommendations are that it is important for our national security and for original stability to retain a presence in afghanistan, that he will ignore that study from the us perspective, is afghanistan, with the us intervention there, a success orfailure? certainly you can say it is not a success because there is still hostilities there is still hostilities there and a struggle between there and a struggle between the afghan government and the taliban, but how you define success in a situation like thatis success in a situation like that is a difficult question. incapacity building military missions, that is one of the toughest questions the military faces, what is the definition of success? it is not being used as a major staging ground for international terror operations, so in that regard

it is a success. ideally, the afghan government will continue to gain strength and legitimacy, but that is not an easy thing to accomplish and certainly not something you can accomplish just with military force. accomplish 'ust with military force. ., , ., force. professor geoffrey corn, thank you _ force. professor geoffrey corn, thank you very _ force. professor geoffrey corn, thank you very much. - force. professor geoffrey corn, thank you very much. thank i force. professor geoffrey corn, l thank you very much. thank you. stay with us on bbc news. still to come: hollywood pushes ahead through the pandemic with the start of its awards season — we'll tell you why this year's golden globe nominations are making history. this is the moment that millions in iran had been waiting for. after his long years in exile, the first hesitant steps of ayatollah khomeini on iranian soil. south africa's white government has offered its black opponents concessions unparalleled in the history of apartheid. and the anc leader, nelson mandela, is to be set free unconditionally. three, two, one. a countdown - to a critical moment.

the world's most powerful rocket ignited all 27 - of its engines at once. and apart from its power, it's this recycling of the rocket, l slashing the cost of a launch, l that makes this a breakthrough in the business| of space travel. two americans have become the first humans to walk in space without any lifeline to their spaceship. one of them called it "a piece of cake". thousands of people have given the yachtswoman ellen macarthur a spectacular homecoming in the cornish port of falmouth after she smashed the world record for sailing solo around the world non—stop. this is bbc news. the latest headlines: protests continue in myanmar as the un calls for the release of deposed leader aung san suu kyi who has been charged by the police following monday's military coup. scientists at oxford university and astrazeneca say they are working in the next generation

of covid vaccines so that the jab can deal with any new variant. canada has designated the proud boys as a terrorist entity, joining a list that includes al-qaeda and the islamic state group. the all male, anti—immigrant group, which describes itself as "western chauvinist", was founded by a canadian. some members were among the supporters of donald trump who stormed the us capitol last month. ben makuch is the national security correspondent for the canadian tv network vice news. he's currently in new york. then, what threat do proud boys pose inside canada. i then, what threat do proud boys pose inside canada.— pose inside canada. i believe they pose — pose inside canada. i believe they pose quite _ pose inside canada. i believe they pose quite the - pose inside canada. i believe they pose quite the threat, i pose inside canada. i believe| they pose quite the threat, in fact. the way i think about this designation is there were four white supremacist groups included in this list and it includes three groups that are bona fides terrorist organisations and proud boys being among them is something thatis being among them is something that is significant because it shows that the government is determined to combat foreign

terrorism the future almost as seriously as they have taken things like isis or al-qaeda. when you look at proud boys they are unquestionably the biggest number group in canada in terms of far right activism and as well as now one of the biggest terrorist groups in canada. their numbers are in the thousands. in canada. their numbers are in the thousands.— the thousands. in the thousands?! - the thousands. in the thousands?! it - the thousands. in the thousands?! it is - the thousands. in the - thousands?! it is believed to be in the _ thousands?! it is believed to be in the thousands. - thousands?! it is believed to be in the thousands. one - thousands?! it is believed to be in the thousands. one of| be in the thousands. one of their telegram channels, which is an encrypted chart at, think it is close to 4000 people. they have had mass demonstrations in canada in the past. they splintered last year, they were big enough to be cut in half and still be quite numbered. it is something thatis quite numbered. it is something that is a serious concern in canada, notjust for national security and intelligence agencies but local police. what -ractical agencies but local police. what practical consequences - agencies but local police. what practical consequences will. practical consequences will this step have?— this step have? welcome i think, quite _ this step have? welcome i think, quite literally, - this step have? welcome i | think, quite literally, there are financial repercussions to this. in the case of isis and

al-qaeda, some of the members who have been identified in canada have been fairly fast, because many of them are hiding, but when it comes to proud boys of their faces have been out in the opening media reports, and pictures, online and social media. some have even declared it. we're talking about of people who will wake up about of people who will wake up tomorrow and they are going to be on lists that allow banks to be on lists that allow banks to cut ties, cut your bank account, allows the government to seize assets, and also charge you criminally your involvement in the organisation. it adds teeth to legislation, allowing police to go after these groups. we should also say that the proud boys have been very, they have done a lot of terminal things in the past, like street fighting and defeating public properties. there were things on the books the police could get these individuals on, but now it is much easier, just for the membership alone or a picture of a yellow and black fred perry showed at a proud

boys relecom comigel mr levy membership to this group. hour membership to this group. how closely does — membership to this group. how closely does canada _ membership to this group. how closely does canada with the united states on this? extremely closely. the canadian national security establishment is extremely dependent on the united states. friendly, canada as part of the five eyes which includes the united kingdom, new zealand, australia, and the united states. there is a lot of intelligence sharing. when it comes to the fbi the fbi gives information to the rcmp, company national police force in canada, and the fbi's crack down, especially since capitol hill, what happened on the sixth, cracked down very hard on proud boys. i'm sure some of that information stephanie foster the canadian government. ben makuch, thank you so much. —— was passed onto. a 22—year—old american has had the world's first successful face and hands transplant and has been talking about the surgery. joseph dimeo, who suffered 80% burns to his body after a car accident in 2018, said he felt really grateful. mark lobel has this remarkable story which contains images of the patient�*s

original injuries. newjersey and —— newjerseyan joseph dimeo was a fun loving teenager and son, by the 22 —year—olds of his life turned upside down when, after a night shift, he fell asleep at the wheel. his vehicle exploded, his body severely burned. his parents became his carers. his fingertips were amputated, he lost his lips, ears, and eyelids. lost his lips, ears, and eyelids-_ lost his lips, ears, and e elids. , ., eyelids. most people without amount of— eyelids. most people without amount of bones _ eyelids. most people without amount of bones they - eyelids. most people without amount of bones they don't l amount of bones they don't survive. he essentially had a 6% chance of identifying someone that would be a proper donorfor him. someone that would be a proper donor for him.— donor for him. against the odds, donor for him. against the odds. a — donor for him. against the odds, a donor _ donor for him. against the odds, a donor was - donor for him. against the odds, a donor was found l donor for him. against the | odds, a donor was found in august. days later, a medical team of over 140 in new york replaced both joseph's team of over 140 in new york replaced bothjoseph's hands and transplanted his whole face in a 23 hour procedure, the third ever attempt, but the first truly successful one. so

we can let — first truly successful one. sr we can let you look in a mirror. big smile. see how everything is starting to move. isn't that great?— isn't that great? open your mouth real— isn't that great? open your mouth real wide. _ isn't that great? open your mouth realwide. five - isn't that great? open your. mouth realwide. five months mouth real wide. five months on, joseph is responding well to his new face and hands. the rima to his new face and hands. the primary goal — to his new face and hands. the primary goal for— to his new face and hands. iie: primary goal for him to his new face and hands. tie: primary goal for him was to gain his independence. he's doing amazingly well. it is a testament to him as an individual, his commitment to his therapy, and his willingness to not give up. i can e breakfast by myself and work — can e breakfast by myself and work out _ can e breakfast by myself and work out by myself, even on my days _ work out by myself, even on my days of— work out by myself, even on my days of a — work out by myself, even on my days of a still work out. i'm almost _ days of a still work out. i'm almost there to normal living again — almost there to normal living again it's _ almost there to normal living again. it'sjust, you know, my goal— again. it'sjust, you know, my goal is— again. it'sjust, you know, my goal is to— again. it'sjust, you know, my goal is to move out of my parents _ goal is to move out of my parents people's house again. building — parents people's house again. building up his strength and working out how to print, squeeze, blink, and smile again, joseph is waiting to hear back from the donor's family, who he says he doesn't really know how to thank for giving him such a precious second chance at life. mark lobel, bbc news. movie theatres are closed in many parts of the world due to the pandemic, but

the hollywood awards season began in earnest on wednesday, with the announcement of the golden globe nominees. and history was made, with three women nominated in the best director category. among them chloe zhao, who directed the movie nomadland. our entertainment correspondent tom brook has more. i'm not homeless, i'm just... chloe zhao's picture nomadland, starring frances mcdormand, is a contemporary western, the story of a woman who leads a nomadic life in america's heartland. it's been playing at festivals and at their drive—in venues, and it's generated a lot of awards buzz. for 38—year—old zhao, this, her third film, is a major achievement. she's made history by becoming the first woman of asian descent to land a golden globe best director nomination. obviously, she's pleased by the recognition. i think it's great, i think it's very happy. i love what i do, and anything that can help me keep doing what i love to do, i'll take it. last year, the south korean movie parasite won the top best picture trophy at the oscars.

now, with chloe zhao earning a golden globe nomination, it suggests that hollywood is becoming more open to embracing asian storytellers long marginalised by the industry, especially women. tom brook there. shall we get stuck in? we can now speak to piya sinha—roy who's a film critic and former senior film editor at the hollywood reporter. piya, the women, finally, are in charge. piya, the women, finally, are in charge-— in charge. they have come through- — in charge. they have come through. they _ in charge. they have come through. they have - in charge. they have come through. they have to - in charge. they have come j through. they have to say, in charge. they have come - through. they have to say, this is happening three years after natalie portman at the 2018 golden globes made that very pointed "all—male nominees" when she announced he would. it is good to see we have three women out in this category. there is a film that has shed a bit of light on these rather confusing rules about the eligibility or awards. they have tried to read the rules several times and have got

completely lost. can you help me out? from what i understand and this is a problematic issue with awards, is that a film thatis with awards, is that a film that is designated foreign languages one that would have more than 50% of its dialogue in a language other than english. and in the case of minari, the story of a korean family chasing the american gym in 1980s arkansas, most of the dialogue is in korean, so that has been designated a foreign—language film. but it is an american film. so its exclusion in the best picture categories has been particularly devastating for a lot of people, like myself, a lot of people, like myself, a lot of people from asian cultures who live in america, who lived that immigrant life and no the english life and the at home speaking another language life. and so not to be able to see that film representatives, you know, it's disappointing. pym; representatives, you know, it's disappointing-— disappointing. any other big messes. you _

disappointing. any other big messes. you know, - disappointing. any other big messes. you know, this - disappointing. any other big i messes. you know, this thing with the hfpa, _ messes. you know, this thing with the hfpa, who _ messes. you know, this thing with the hfpa, who nominate messes. you know, this thing - with the hfpa, who nominate the golden globes, it is a mixed bag. i think one of the biggest misses, and i am medically devastated with this one, is the tv show i am a destroyer you, created by michaela cole, it was the best reviewed and received show last year. foretz not at all be included in today's nomination is surprising. when fleabag came along it was nominated, so do not see this show recognised is so disappointing and so it feels we have made some steps forward in some categories and we want to celebrate those wins, but there is still somewhat left to be done. were there any nominations _ somewhat left to be done. were there any nominations that - somewhat left to be done. were there any nominations that made you punch the air with joy? i’d you punch the air with “oy? i'd have to you punch the air withjoy? i�*c have to say, there was some really great nominations in there, somewhat perplexing. for me, personally, personally, was so happy to see the best drama nomination lead actor category,

because he is incredible in the sound of metal for top because he is incredible in the sound of metalfor top end dev patelin sound of metalfor top end dev patel in leading mail in comedy category. they have to say, personally, as a british indian myself, that was really exciting to see the two recognised. you mentioned the perplexing nominations. - recognised. you mentioned the perplexing nominations. name| perplexing nominations. name some names. perplexing nominations. name some names-— perplexing nominations. name some names. james corden for the from _ some names. james corden for the prom. not _ some names. james corden for the prom. not entirely - some names. james corden for the prom. not entirely sure - the prom. not entirely sure what is happening there. emily in paris was very... did no-one like that— in paris was very... did no-one like that as _ in paris was very... did no-one like that as a _ in paris was very... did no-one like that as a guilty _ in paris was very... did no-one like that as a guilty pleasure? l like that as a guilty pleasure? this is the thing, how can you leave out a show like i am a destroyer you and then have emily in paris and then bridget and was a big guilty pleasure for many of us over the holidays. meryl streep did not get any nominations and she has been nominated many times by the golden globes before. there

were various perplexing snubs. the key one for me was in the best drama film and comedy categories, and notably left out movies featuring black ensemble casts, we saw some of those actors get individual nominations, but to leave out movies like spike lee's da five bloods regina king's one night in miami and ma rainey�*s black bottom that was perplexing. piya sinha—roy, it was a pleasure speaking to you. thank you very much. before we go, this year's super bowl stadium will be empty than usual due to covid health and safety protocols. the nfl has invited 7500 vaccinated healthcare workers and 14,500 fans to be at the game. but to fill the rest of the seed the league launched the fan any standard cutout programme. it allows people to upload a photograph of themselves or someone else, it will be printed, the cost $100, a portion of the proceeds will be donated to local charities

picked by the fan's home team. lucky to be a lot of those cutouts. do stay with us. —— to be on one of those. hello there. winter is about to ramp up to another gear by the end of this week, certainly into the weekend. it'll be turning much colder with the risk of some disruptive snow in places. so for the next few days, it'll gradually be turning colder for all, and we'll see increasing snow particularly over the hills in the north. now for thursday, we've still got low pressure close by to the uk, it's the weather front across the north bringing further cloud, outbreaks of rain to northern ireland, much of scotland, northern england too, and here we'll see further snow over the scottish hills accumulating and drifting in that strong east—southeast wind. further south, after a bright start to the day, we'll start to see showery bursts of rain moving up from the south. here, it'll tend to be fairly mild, 8—10 celsius, but very cold across the north where we have that snow. through thursday night, it continues with rain

and the snow across scotland — significant accumulations over the grampians and the highlands, very wet weather with a risk of flooding. further south, a drier night to come and clear skies, could see some mist and fog across southern england, and again, a big temperature contrast from north to south. now the snow continues as we head on into friday and saturday — significant accumulations have prompted the met office to issue an amber warning for this heavy, incessant snow. and also, some very heavy rain for lower levels could cause some localised flooding — so a whole host of issues there. further west, we'll have sunny spells, a few showers, tends to stay dry across the far south—east — again, 9—10 celsius, much colder further north where it will also be windy with that drifting snow in the hills. moving on into the weekend, our area of low pressure sinks a bit further southwards, so it means the rain and the hill snow across scotland will drift into parts of northern england at times too, so a whole wintry mix here could be disruptive. further south, quite a bit of cloud around with outbreaks of rain, and temperatures dropping generally across—the—board. still cold in the north and a little bit colder for much of england and wales, too. as we head on into sunday, the very cold air across the east pushes southwards right across the uk, and it'll be very windy,

so the wind making it feel even colder — 2—3 celsius, some snow pushing into northern and eastern areas which could be disruptive. so turning very cold through this weekend for all areas, with the risk of some disruptive snow for some of us.

this is bbc news,

the headlines: protests are continuing in myanmar as the un urges the world to make sure the military to fail. the deposed factor leader has been accused of illegally possessing 2—way radios and breaking election laws. sciences from oxford and astrazeneca say they are working on a generation of vaccines so that the jab can be adapted to work on different strains of the virus. the virus is already mutating, first here in the uk and also with new variants detected in resilient south africa. commission's for crisis management wants the afghan stalled peace protest is facing high possibility of failure. in addition, a bipartisan report of the us congress has strongly urged president biden to delay a trump administration plan to pull out all us forces by may. now on bbc news —

wednesday in parliament.