welcome to bbc news — i'm lewis vaughanjones. our top stories: south africa pulls the oxford—astrazeneca jab from its upcoming vaccine programme after a study shows disappointing results against the country's coronavirus variant. protests against myanmar�*s military coup continue, now becoming the country's largest in over a decade. former us secretary of state george shultz, whose negotiating helped end the cold war, has died. a breakaway glacier washes away a dam in northern india. the flooding kills at least nine people — more than a hundred are missing. and brady brilliant — tom brady wins his seventh super bowl as

his buccaneers terrorise the kansas city chiefs. hello, welcome to the program. we start in south africa which is to delay and review its use of the oxford—astrazeneca vaccine after a study showed disappointing results against the local variant of coronavirus. it comes less than a week after the country's president and senior ministers greeted the arrival of a million doses of the jab as they landed atjohannesburg airport — and is a setback for innoculation efforts which had been due to start in the coming days. south africa's health minister had this to say. our scientists must quickly sit together and figure out what approach we are going to use in order to effectively deploy the astrazeneca vaccines.

it must be clear when that can be done, what conditions need to be fulfilled, what we need to do about all of that. so that basically is the assignment that has been given to our scientists all together. they'll figure it out, they'll come back to us and say, this is the proposal on the astrazeneca. so it's a temporary issue that we have to hold onto astrazeneca, it is temporary until we figure out these issues, what are the next steps supposed to be. when we know those steps, then of course we'll bring it back. scientists behind the oxford astrazeneca vaccine say it should still prevent people needing hospital treatment or dying, if infected with the south african variant. around 100 cases of the variant have been identified in the uk. our medical editor fergus walsh reports on the latest research and the ongoing effort to combat emerging strains of the coronavirus. snow and ice did not stop the vaccination drive in ipswich today. there is now a road, albeit a difficult one, out of the pandemic.

but there's concern that current vaccines being used at thousands of centres across the uk might eventually lose some of their potency as coronavirus evolves. the oxford astrazeneca jab works well against the kent variant first seen in september and now dominant in the uk. but a small study of 2,000 young adults in south africa suggests it gives minimal protection against mild and moderate disease caused by the variant there. even so, scientists in oxford are confident that it would still prevent serious covid disease. maybe we won't be reducing the number of cases as much, but we still won't be seeing the deaths, the hospitalisations and the severe disease, and that's really important for health care systems. even if we are having mild and asymptomatic infections, to prevent people from going to hospital with covid would have a major effect. coronavirus is constantly mutating. most changes aren't a worry.

vaccines use the gene from the spike protein to train the immune system, so if this code mutates, as it has in the variants from south africa, brazil and kent, it may make the virus less visible to antibodies. thankfully, t cells, another part of our immune system, look like they can spot infection, meaning existing vaccines should protect against severe disease. more than 100 cases of the south africa variant has been found in the uk, and house—to—house testing in affected areas is under way in a bid to suppress its spread. but it's inevitable that more variants will emerge. the oxford team are creating prototype vaccines against several variants and say they'll be ready, if needed, by the autumn. coronavirus immunisation may become an annual event.

we see very much probably an annual or a booster in the autumn, the way we do with flu vaccinations, where you look at what variant of virus is spreading round the world, you rapidly produce a variant of vaccine and then begin to vaccinate and protect the nation. the more coronavirus mutates, the less likely it is that transmission can be stopped. it means covid will probably be a permanent threat. but like other diseases, mostly preventable by vaccination. fergus walsh, bbc news. the latest on the military coup in myanmar now. a nationwide strike is expected today in protest against last week's military coup. sunday saw the largest protests in the country in more than a decade, with tens of thousands of people demanding the release of the elected leader aung san suu kyi. from bangkok our correspondent jonathan head reports. they started marching

in the morning, and the numbers just kept growing. if the soldiers who unseated myanmar�*s elected government on monday thought their coup would be unopposed, thousands came out to prove them wrong, filling the streets. chanting. "democracy is our right", they chanted, "ending dictatorship, ourwill". horns honk. the traffic was forced to a crawl and cars sounded their horns, not in anger, but in support, and in defiance of the police, who mutely watched as yangon city centre was taken over. many wore or carried the colour red of the national league for democracy, the deposed party of aung san suu kyi. and everywhere, herface. she's still in military custody, but very much the symbol of this growing resistance movement. chanting. translation: we don't want

to go back to military rule. i we don't want to live in fear. we want mother suu to be freed from being under detention unjustly. translation: they can block the internet and other - communications, but they can't block people's ears, their mouths and their brains. the security forces made no attempt to break up the massive crowd. some traffic police even handed out water. just for a moment, you could forget that a popular leader had been overthrown at the point of a gun. but the momentum behind this movement must worry myanmar�*s military rulers. there were similar protests across the country — in the second city, mandalay, a surprisingly big march in remote and mountainous chin state, and even in the military�*s own citadel, the fortress—like capital naypidaw, a noisy rally of protesting motorbike riders. the military may hold all the levers of government, but for now, the streets belong to the people. after an anxious and

dispiriting week, there was relief and enjoyment in these protests. but the army has killed thousands before to shore up its power. it may do so again. jonathan head, bbc news. police say at least a hundred people are missing and several dad after a glacier burst in northern india. a sabre so quickly there was no time to sound the alarm. rescue operations have been taking place and survivors are being pulled from the pub and rubble. it happened in the district of chamoli. our deli correspondent has the latest.

this dramatic footage shows when the nanda devi glacier in the himalayas burst on sunday morning. as water gushed down the valley, damage and destruction. translation: about 50-100 people were running - for their lives, but couldn't be saved, and they were engulfed by the river. the situation here is still dangerous. people are leaving their homes and are fleeing towards the forest. with floodwaters rising and roads and homes destroyed, an urgent rescue operation was under way. hundreds of members of the indian military and disaster response units have been deployed to the area. translation: approximately 125 people could be missing - as per the estimates, but it could rise because the power company is unable to give the exact figures. everyone is busy in the rescue operations. cheering. a moment of hope, as workers rescued one man from this tunnel, but dozens more

are still feared trapped. officials say two power plants, employing more than 150 people, were also hit. many of the workers remain unaccounted for. hospitals are on standby. in a tweet, india's prime minister's, narendra modi, said he was constantly monitoring the situation. "india stands with uttarakhand," he said. rajini vaidyanathan, bbc news, delhi. president ronald reagan's long—time secretary of state, george shultz, has died aged 100. mr shultz spent most of the 1980s trying to improve relations with the soviet union and forging a course for peace in the middle east. paul hawkins looks back at his life. he is widely credited with helping to end the cold war. thank you very much, mr president and my friend. george shultz served for 6.5 years under ronald reagan. during that time he helped improve relations with the soviet union, striking

relationships with gorbachev and his foreign minister, eduard shevardnadze. in negotiations, he refused to make concessions in advance, waiting for them to blink and they usually did. it will help us to remove some misunderstanding... because as he well knew, they had become more concerned with problems at home than interference abroad. in 1987, both countries signed a landmark arms control agreement. he was involved in talks with iran in the 1980s. the iranians are known as great rug merchants, not for nothing. the iranians are good at this business of smiling and encouraging you on, and then cutting your throat. in total, he served three presidents, dwight eisenhower and richard nixon here. his public service following an impressive academic career which saw him become a distinguished fellow of the hoover institution. its director, condoleeza rice, a former secretary of state

herself, called him a "great american statesman and a true patriot." while the current secretary of state said he was a "legend and an ardent champion of diplomacy." george shultz chose words instead of weapons to end the cold war. last december, to celebrate his 100th birthday, he wrote in the washington post, "trust is the coin of the realm. when trust was in the room, good things happened. when trust wasn't, good things did not". george shultz who has died aged 100. stay with us on bbc news, still to come: making history again — tom brady wins his seventh super bowl, this time with the tampa bay buccaneers. there's mr mandela, mr nelson mandela, a free man, taking his first steps into a new south africa.

iran's spiritual leader ayatollah khamenei has said he has passed a death sentence on salman rushdie, the british author of a book which many muslims say is blasphemous. the people of haiti havej flocked to church to give thanks for the ousting - of their former president, ba by doc duvalier. because of his considerable value as a stallion, shergar was kept in a special secure box in the stud farm's central block. shergar was driven away in a horse box the thieves had brought with them. there stepped down from the plane a figure in mourning. elizabeth ii, queen of this realm, and of all her other realms and territories, head of the commonwealth, defender of the faith. the headlines. south africa

pulls the oxford astrazeneca jab from its upcoming vaccine programme after the study shows disappointing results against the country was my coronavirus variant. their protests in myanmar after last week's military coup. in sierra leone, sex workers are often shunned. the bbc has been uncovered a world where many are abused and even killed. long before covid—19, many in the city were struggling to survive, but for the sex workers, the coronavirus has made the struggle even harder.

there are more than 1000 sex workers in makinu. even though theirjob is legal, they get no government aid during the pandemic and the risks they face have not diminished. many like this woman have children to provide for and no man around to help. she shows me the injuries she sees are inflicted on her by clients.

a few weeks later, when i go back to see how she has doing, she has disappeared. two months pass with no word from aysata. then out of the blue, i get a call from a number in mali. it is aysata and another sex worker. we are taken there. aysata says they were trafficked to mali where they were abandoned in the small mining village. we pinpoint

their location. it's one hours�* drive their location. it�*s one hours�* drive from the town kenieba. we organise their rescue. international organisation for migration, a un body which aids trafficked people, organised their return to sierra leone. we are all here ready, outside, they are waiting for their daughters, they can�*t wait. it's daughters, they can�*t wait. it�*s a joy, you know? it�*s a celebration for me in my mind and my heart because i was not thinking it�*s going to turn out this way. we are happy that these girls are finally coming back. these lives that were almost lost, we regained them. today, the mothers have their daughters on the daughters have their mothers back. the question is, what kind of life awaits them now?

the president of haiti says an attempt to kill him and overthrow the government has been foiled, amid a dispute over when his term ends. at least 23 people were arrested, including a topjudge and a senior police officer for the alleged �*coup attempt�*. the president insists his term in office ends in february 2022. but opponents say it finished on sunday. protesters took to the streets of the capital port—au—prince and other towns over his refusal to step down. translation: today, we do not recognise jovenel moise - as president because his mandate is over. according to the constitution and electoral law, jovenel�*s mandate is over. haiti prime ministerjoseph jouthe has called for calm and dialogue.

translation: let's call for calm, dialogue. - i�*m not violent and i don�*t like violence. violence makes no sense. participate in the next elections. talk to the people and participate in the elections. that way, you can take power. american football — and another chapter has been added to the legendary career of tom brady. at the age of 43 he�*s led the tampa bay buccaneers to victory in the super bowl. they beat the kansas city chiefs by 31 points to 9 in florida. it�*s the seventh time he�*s won the title — melissa jacobs — who�*s written for the guardian and sports illustrated amongst others — and is managing editor of �*the football girl�*. we have run out of adjectives to describe brady. maybe we�*ll start to consider him as a future hall of famer. he isjust gold. for this franchise as well,

in one year, they did have a lot of pieces in place, mind you, but to see how they evolved over the course of the year, and to win seven super bowl rings is just beyond incredible. and there are so many good young quarterbacks in the league at the moment, we can�*t look far past his opponent today, patrick mahon �*s, who won the super bowl last year, they all seem to have such athleticism, strong, powerful arms, and tom brady doesn�*t have any of that he would like to say he has some semblance of athleticism, but he has lasted so long by basically any time anyone pressures him, he just falls to the ground and doesn�*t try to scramble. he is definitely an old relic, but it�*s working! the thing that tom brady really brings that some of these other guys, including patrick mccombs, who is phenomenal and can read the field as well as anyone, tom brady has seen every kind of defence. he knows how to react to any kind of situation, and someone can

win a race against him, but you can�*t quantify how important that is. some people were saying it wasn�*t the greatest game of american football ever, it wasn�*t the best advert for the sport particularly, butjust tell us what it means to the culture and psyche of america. there was a lot of hype surrounding this game but the spectacle of the super bowl transcends the football itself, and their... 7500 vaccinated healthcare workers that were in the stands and honorary captains who were community heroes during covid, there was a lot of honouring of those types of people, so a lot of good fuzzy feelings, no matter who you are rooting for in this game.

they say laughter is the best medicine and during the pandemic, the leicester festival is on line. laughter. there�*s nothing like a good lockdown laugh. in what has been a miserable year, the chance to chortle is being leapt at by these comedy fans who would fill theatres pre—pandemic to see comics like felicity ward. you had to be in the room, they�*d say. yes, this is an adventurous choice of trouser. well, now, you have to be in the zoom. welcome to the first night of the leicester comedy festival 2021! the leicester comedy festival is normally a mixed—bill, multi—venue event.

now it�*s a purely online experience. i know what i have to do, i like to engage with the audience, that�*s what i used to do in olden times. hey, how is everybody doing? there�*s even a sense ofjeopardy that somebody might at home might leave their mic on while shouting at a family member. shouting. bring it to me, please! this is how i dress. i am from an area called millwall. prince abadi also performed on opening night from his makeshift stage at home, all alone, no audience energy to work with. it can�*t be easy. it�*s a bit strange performing to people at home, and you see how well some people live, like, idid a gig to the other day to two people in a hot tub. so it�*s a bit odd for the performers, but what about the audience? what you can�*t see is, i�*ve got my pyjama bottoms on. i felt a bit self—conscious at the beginning because you don�*t have the cover of darkness.

i wish we could all be in the same room. as close as being at a real gig as it can be, especially when they let you interact and they talk to you and you can hear other people laughing. i love it. can you see that, bbc? experienced comics have adapted their acts for a domestic setting, but is the popularity of live streamed gigs a quick counter—covid fix or a game changer? it will absolutely change the landscape of comedy and what it has done already, it�*s included a bunch of people that often have to assess whether they can go to a gig, people with physical disabilities, people with social anxiety. i think that what it will allow is, people will start to think internationally now when they�*re doing a live gig. laughter. there are downsides to this technology that we all know about. she�*s frozen. but that�*s perfectly fine. the one big advantage is, if you want to quietly leave the room, you can do so without fear of being picked on or humiliated. will gompertz, bbc news.

london�*s tiniest house is for sale forjust under £1 million, or1.3 million us dollars. it measures just 1.7 metres in with. estate agents describe the five floor house as a bit of london magic. it was a victorian hat shop originally. we can go live to myanmar main city of yangon. this is the third day of protests, this after the military coup of course last week where the defect or elected leader aung san suu kyi was seized along with others. they were due to convene a new parliament and in the military stepped in another people have stepped out onto the streets, protesting against that military coup. that is it

from me. hello. we have a particularly cold week ahead across the uk, as we are set to sit in arctic air with biting easterly winds, particularly for today and tomorrow. subzero wind chill in all parts during the first half of the week. that�*s going to bring hit and miss snow showers. many in the west will avoid them. hard overnight frosts return this week as the winds feel lighter. but later less cold air will try to push its way as you can see, we�*ve got the easterly winds dominating the cold air for much of the week. but as milder atlantic air tries to push in, that boundary line could bring some snow into the west, but the question mark is how far that boundary gets in? it looks like the cold air will, by and large, win out. and certainly on sunday the cold air brought the snow showers across kent and parts of east anglia. it�*s these areas right until midday on monday the met office amber

weather warning remains in place. there will be a covering of snow elsewhere in eastern parts of england. eastern scotland as we start the day from snow showers through the night. fewer in the west, all starts with subzero temperatures and of course the chance of some ice. now into monday, snow showers in the west are few and far between. there will be a few light flurries here and there. eastern areas are most prone, but even here some will stay dry. but we will see those snow showers form into core doors, one through lincolnshire to the peak district, and another one aberdeenshire through to kinross. snow could mount up. 5—15cm of snow blown along by some pretty strong winds. strongest winds to the south and east with a big impact on temperature. on the thermometers it has zero to 3 degrees potentially. the wind could feel as cold as around —7 or —8 through the afternoon in east anglia and the southeast. that cold wind—chill then continues into tuesday. further snow flurries coming in. the winds subtly

shifting direction, could be a different line particularly for the central belt of scotland. one through east anglia and towards the home counties. and we also have got to watch for a weather system just getting close to cornwall and also across into parts of the channel islands, that could bring some sleet and snow here. but another day of subzero wind—chill for all of us. as you go through into wednesday, the winds will ease. notice how the isobars opening out a little bit. that means we will see a very cold start with lighter winds, particularly across the snowfields of scotland we could see temperatures as low as around —13 or —14. the snow showers that we do see want to be driven as far west either. many towards the eastern areas, most though on wednesday will have a dry and bright day. still pretty cold but with less of a wind—chill out there. bye for now.

this is bbc news, the headlines: south africa is to delay and review its use of the oxford astrazeneca vaccine after a study showed is appointing results against the local variant of coronavirus. it comes less than a week after the countries received 1 million doses and just days before its inoculation programme was set to begin. a third day of protests has taken place in myanmar, a week after the military seized power in a coup. more than 1000 are set to be on the main city gang gone, calling for the restoration of democracy and the release of the leader aung san suu kyi. tom brady has extended his record of super bowl bins —— wins with a seventh title. now on bbc news, it�*s time for hardtalk.