this is bbc news: i'm sally bundock with the latest headlines for viewers in the uk and around the world. us and european authorities pause the rollout of the johnson & johnson jab — it's now the latest covid vaccine linked to blood clots. you are much more likely to have a severe adverse outcome if you catch covid. this is a thing that is much more likely to cause plots. calls a major uk trial into mixing covid vaccines is being expanded. calls for an end to rising violence in the us following the shooting of a black man by police on sunday.

rising tensions over russia's military build—up next to ukaine — president biden suggests a summit to russia's president putin. lockdown legends — a rolling stone and a foo fighter call for some optimism as the pandemic eases in the uk. hello and welcome. the us, south africa and the european union are to temporarily suspend the rollout of thejohnson & johnson covid jab, after reports of rare blood clotting. the american health authority, the fda, said six cases were detected among more than six million americans who received the single dose vaccine. johnson &johnson said it has paused its eu rollout.

here's our medical editor fergus walsh. an abundance of caution was cited by us health officials as the reason why they paused the use of the single—shotjohnson &johnson covid jab. the vaccine, which in europe is branded as janssen, was approved in the us in late—february. since then, there have been six incidents of very rare clots in the brain, out of 6.8 million doses. so less than one case per million people immunised. all were women under 50, one of them died and one is critically ill. i think this is an unusual occurrence of a serious adverse event that you want to make sure before you go forward, you investigate it thoroughly. and that's exactly what they're doing. they're pausing, so that they can look at it more carefully. similar very rare clots have occurred with the oxford—astrazeneca jab and scientists are investigating whether this type of vaccine

technology could be implicated. 30 technology could be implicated. million doses ofjs are 30 million doses ofj&j vaccine are on the way for the uk although it is yet to be approved. it is hoped the delay in the roll—out will not slow the vaccine drive here. in the roll-out will not slow the vaccine drive here. they are global — the vaccine drive here. they are global workhorses - the vaccine drive here. they are global workhorses of. the vaccine drive here. they| are global workhorses of the vaccination programme. it is a lot of vaccine that potentially may not be used. i think that would be tragic because you are much much more likely to have a severe adverse outcome if you catch covid. this is the thing which is much more likely to cause plots than the vaccine. the biggest concern is globally. the plan was to immunise 1 billion people worldwide immunisei billion people worldwide with the vaccine this year to do if that is disrupted, it will slow efforts to finally bring the pandemic under control.

a major uk trial looking at whether covid vaccines can be mixed, with different ones used for first and second doses, is being expanded. adults over 50 who have had a first dose of pfizer or astrazeneca can apply to take part in the com—cov study. their second dose could be the same again or a shot of moderna or novavax. health reporter michelle roberts has more. currently the nhs offers people an identical covid—19 vaccination for their first and second doses. but some experts believe switching to a different brand of vaccine for the second may give a broader and longer lasting protection against the pandemic virus and new variants of it as well as more flexibility in the vaccine rollout. more than 800 people have been helping researchers investigate is in a trial. they received two doses of either pfizer, astrazeneca or a

combination of both to see which works best for immunity. results from the first stage are expected next month but the investigators now hope to recruit around 1000 people aged 50 or older to take part and test more vaccines in different combinations. that includes the new moderna vaccine and the novavax one expected to be approved soon in the uk. those with one and — approved soon in the uk. those with one and then _ approved soon in the uk. those with one and then with - approved soon in the uk. those with one and then with the - with one and then with the other and then that gives more flexibility with issues such as supply or a change in recommendations for different age groups. it also means the not locked into getting the same vaccine for a second dose. we will test those combinations against the new variants as they come through. we will test they come through. we will test the blood test against new variants to see if they offer any broader protection against multiple different strains. volunteers need to have already had one covid jab on the nhs in the past few months and be willing to travel to original

nhs hospital trust site england to take part. they will have blood taken to check how well the vaccine immune response is triggered. this study will run for one year but there should be reportable findings byjune orjuly to shape how the uk and the world continues to protect populations against this virus. in the minneapolis suburb of brooklyn center, demonstrators are filling the streets for a third night of protest against the fatal shooting of daunte wright — a 20—year—old black man — at the hands of police. the authorities have delcared the situation an unlawful assembly. these are the live pictures from the scene. crowds have defied the curfew to congregate outside the police headquarters. earlier, the policewoman who shot daunte wright resigned — as did the police chief. tensions are high in minneapolis as the trial

of the ex—officer accused of killing george floyd continues. let's speak to our north america correspondent peter bowes. peter, a third night. what happened? and there is clearly still a tremendous amount of anger and frustration on the streets which is why we see these protests, as you say, for a third night running in this area close to where daunte wright was shot dead by a female officer who, it was said, by the police, accidentally drew her gun and fired the shot instead of grabbing her taser. she has resigned as has the police chief for the area and the mayor a little earlier was saying that he at least hope it would calm things down a little bit and bring some peace to the streets. that clearly has not happened because this area has been thronging with people and protesters clashing with the

police and once again the area and the gathering declared an unlawful assembly and the police using bull horns to warn people of they did not immediately go home that they would be arrested and indeed quite a few people have been arrested and led off. and all this comes as the trial that you mentioned, the murder trial is drawing to an end. it is quite possible that both sides will rest by next week and it will rest by next week and it will be in the hands of the jury. will be in the hands of the 'u . �* will be in the hands of the jury. after the fatal shooting on sunday. _ jury. after the fatal shooting on sunday, the _ jury. after the fatal shooting on sunday, the police - on sunday, the police department issued body camera footage quite quickly and explained what happened quickly. the officer has resigned and the police chief has ruined designed and they are trying to show that things are trying to show that things are changing. —— the police chief has resigned to they are trying to show transparency in relation to this particular tragedy by releasing that video footage very quickly. the reason i _ footage very quickly. the

reason i think _ footage very quickly. the reason i think many - footage very quickly. tue: reason i think many people footage very quickly. tte: reason i think many people are still angry and frustrated about is is because they do not yet have answers. they do not have a reason nor an explanation as to why the police officer acted in the way that she did. clearly there is an investigation under way and thatis an investigation under way and that is continuing to president biden has spoken about this as well and he is also waiting for that investigation to play out before it can be determined whether she deliberately shot to kill, and it is a real possibility, if that is the conclusion, she will face charges to but for now she has left the fourth anterosuperior has left the force as well and the city remains on edge. thank ou, the city remains on edge. thank you. peter— the city remains on edge. thank you. peter and _ the city remains on edge. thank you, peter and we _ the city remains on edge. thank you, peter and we will- the city remains on edge. thank you, peter and we will speak . the city remains on edge. thank you, peter and we will speak to | you, peter and we will speak to you, peter and we will speak to you again soon. us presidentjoe biden has urged russian president vladimir putin to ease tensions on the ukrainian border and suggested they hold their first summit. this comes as tensions rise over russia's military build—up next to ukraine. the bbc�*s north america correspondent aleem maqbool

reports. it is the biggest russian troop movement in seven years to over recent weeks, mobile phone footage started to emerge of long columns of military vehicles heading towards the ukrainian border. and the other russian defence ministry is proudly releasing footage of military aircraft and boats heading that way as well. a few days ago the ukrainian president made a dramatic visit to the front lines where his country's army has been fighting russian backed rebels. part of an appeal for help from the outside world. and others are now seeing a need for urgency. in brussels, the us secretary of state met a ukrainian delegation to discuss theissue ukrainian delegation to discuss the issue with a promise that the issue with a promise that the us will increase its military presence in the region. and nato has called the

russian buildup of troops unjustified and unacceptable and want moscow to withdraw them. ~ them. we are seriously concerned _ them. we are seriously concerned by _ them. we are seriously concerned by ongoing l concerned by ongoing developments and nato is monitoring the situation very closely. in recent weeks, russia has moved thousands of combat ready troops to the borders of ukraine. the largest massing of russian troops since the illegal annexation of crimea in 2014.- the illegal annexation of crimea in 2014. more than 13,000 crimea in 2014. more than 13.000 people _ crimea in 2014. more than 13,000 people have - crimea in 2014. more than 13,000 people have been| crimea in 2014. more than - 13,000 people have been killed in the conflict since 2014. that after months of relative calm, things have escalated of late with ukraine reporting troops being killed with increasing regularity. but why now? many believe this is about vladimir putin reacting to tougher language from washington and attempting to assert dominance over the new biden administration. t assert dominance over the new biden administration.— biden administration. i think putin believes _ biden administration. i think putin believes that - biden administration. i think putin believes that the - biden administration. i think

putin believes that the west j putin believes that the west actually is a paper tiger, that they have tough language but not willing to step up militarily or in any other way to confront russia. so he is trying to prove the hollowness of the western position as he sees it. , ., ., sees it. does he have a point, to an extent? _ sees it. does he have a point, to an extent? i _ sees it. does he have a point, to an extent? i think - sees it. does he have a point, to an extent? i think that. - sees it. does he have a point, to an extent? i think that. i i to an extent? i think that. i think it is — to an extent? i think that. i think it is conflict _ to an extent? i think that. i think it is conflict with - think it is conflict with russia about ukraine. no—one is going to go to war over that. for its part, vladimir putin says there is nothing wrong with moving troops and it been responding to aggression from the west. translation: interest bonds to the latest military action that threatens russia we have taken appropriate measures as part of the control measures and exercises during the winter training period, a check of the combat readiness of the troops if the western and military districts was carried out. for

ears, districts was carried out. for years, ukraine _ districts was carried out. for years, ukraine has - districts was carried out. for years, ukraine has been pushing tojoin nato to years, ukraine has been pushing to join nato to the annoyance of the kremlin. even if it happens, and there are no it will take years. and there is a nagging fear for some that this troop buildup, president putin may be doing more than just posturing. stay with us here on bbc news. so much more to come. all the latest sports news including holders bayern bowing out of the champions league. pol pot, one of the century's greatest mass murderers, has reported to have died of natural causes. he and the khmer rouge movement he led were responsible for the deaths of an estimated 1.7 million cambodians. there have been violent protests in indonesia, where playboy has gone

on sale for the first time. traditionalist muslim leaders have expressed disgust. the magazine's offices have been attacked and its editorial staff have gone into hiding. it was clear that paula's only contest was with the clock. and as for her sporting legacy, paula radcliffe's competitors will be chasing her new world best time for years to come. shouting. quite quietly but quicker and quicker, she seemed tojust slide away under the surface and disappear. this is bbc news, the latest headlines: us and european authorities pause the rollout of the johnson & johnson jab. it's now the latest covid vaccine linked to blood clots. a major uk trial into mixing covid vaccines is being expanded.

let's stay with that story now: dr mati hlatshwayo davis is an infectious disease physician at thejohn cochran veterans medical center as well as a st louis board of health member. starting with thejohnson & johnson back then, what you think about the stopping of the vaccine and implications of the blood clots?— blood clots? frankly, it rocked all of us in _ blood clots? frankly, it rocked all of us in the _ blood clots? frankly, it rocked all of us in the scientific- blood clots? frankly, it rocked all of us in the scientific and i all of us in the scientific and medical community in the united states but for me, personally, i was absolutely thrilled to see this administration be so transparent, with news that could have been a setback for vaccine confidence overall. but

that transparency is exactly what is needed to regain trust in the communities of colour that have been particularly hard hit and for him to historically the transparency and respect for their lives and dignity has not always been there. for me, i believe you transparency is key. moving past that, however, from a medical standpoint, past that, however, from a medicalstandpoint, it past that, however, from a medical standpoint, it is the responsible thing to do. once you see a signal, even a signal this rare, it is important to pause, take a look at the data and really understand the context in which it exists. while these numbers are again exceedingly rare, compared to the general risk of getting blood clots without a vaccine, and certainly much lower than the risk that women have for example, women taking birth control pills, it's like to be clear about how it will impact women and to what degree so

that they and their providers can make the best available choice for them, informed consent, before making a decision. consent, before making a decision-— consent, before making a decision. ~ ., ., decision. do you know and can ou decision. do you know and can you exolain — decision. do you know and can you explain how _ decision. do you know and can you explain how the _ decision. do you know and can i you explain how the astrazeneca and johnson & johnson vaccines are and johnson &johnson vaccines are similar because that is what is being looked into, isn't it, the way the vaccines are formulated, there could be are formulated, there could be a key as to why blood clots are a key as to why blood clots are a possible side effect. figs a key as to why blood clots are a possible side effect.- a possible side effect. as you know, a possible side effect. as you know. the — a possible side effect. as you know, the two _ a possible side effect. as you know, the two main - a possible side effect. as you know, the two main vaccine l know, the two main vaccine product that came on the market where from pfizer and moderna and they used an nrma vaccine technology which really relies on genes —— nrma, which provides a protein to stimulate antibodies, and these vaccine is different in that they use another family of viruses as the backbone for again being able to develop immunity within ourselves. it will be the task

of researchers both he and internationally to understand what it is about this particular technology that may be causing the blood clots, however, like asset, these are exceedingly rare and throughout the of vaccines, even with the covid vaccine if we are being honest, there will always be a signal toward side—effects that needs to be taking a closer look at. for me, this is less about leaning into today a definitive concern that the signal will cause widespread morbidity or mortality, but it is more about preparation and understanding because, again, healthcare systems need to be prepared. communities need to understand the best context to use and not use these vaccines. for me, this is about an appropriate public health concern than anything else at

this stage until we have more information.— information. sorry to interrupt, _ information. sorry to interrupt, but - information. sorry to interrupt, but i - information. sorry to | interrupt, but i would information. sorry to - interrupt, but i would like to ask you briefly on your thoughts about mixing vaccines, the getting a dose of one and a different dose for your second dosage. what do you think about that? tn dosage. what do you think about that? ., dosage. what do you think about that? . ., ., �* , that? in an idealworld, it's not something _ that? in an idealworld, it's not something we - that? in an idealworld, it's i not something we recommend because the phase three clinical trials done have been done with one vaccine and following in that way. until we know for sure if mixing doses will have efficacy, the efficacy that we hope to protect people, i would not lean into this at this stage. all right, thank you so much for sharing your expertise on the bbc. very much appreciated. now it's time for the latest sport from the bbc sports centre. hello, i'm austin halewood with your latest sports news. we start with football because the champions league holders, bayern munich, are out of this year's competition. they were beaten on away—goals by paris saint germain.

eric maxim choupo—moting scored the only goal of the second leg to give bayern a 1—nil win, but it wasn't enough, after psg won last week's first—leg 3—2. the victory takes mauricio pochettino's side into the semi—finals, but despite already knocking out barcelona, and now bayern, he doesn't believe they're the favourites. no. translation: ., ~ translation: no, i don't think so, we translation: n0, i don't think so, we knocked _ translation: n0, i don't think so, we knocked barcelona - translation: no, i don't think so, we knocked barcelona out i so, we knocked barcelona out over the round of 16 x two legs and our bayern munich and i think we deserve to win both games but i do not think paris saint—germain other favourites to win the champions league, there are still tough opponents. chelsea are also through to the last four, after a 2—1win on aggregate against porto. a spectacular late goal from mehdi taremi gave the portuguese side the victory on the night, but chelsea did enough to protect their lead from the first leg, and reach theirfirst champions league semi—final

for seven years. it isa it is a big step to be in the semi—final and this is a very very big achievement and to see when chelsea has been in the semifinals so we are not used to being there and once you are there, you play for the final. the other two quarterfinals conclude later on wednesday, with manchester city still on the hunt for what would be an historic quadruple. city are 2—1 up after the first leg of their tie with borussia dortmund and this is the competition manager pep guardiola was brought in to win, having lifted the title with barcelona. this is a business, and the business is business and business is business and business is business and business is to win. if you do not win, i will be a failure. if we win, then it will be how goodis if we win, then it will be how good is pep! in the other game,

jurgen klopp's liverpool have a 2—goal deficit to overturn against real madrid at anfield if they're to set up an all—english semi—final against chelsea. the spanish side lead 3—1 after last week's first leg in madrid. liverpool will be looking to recreate their heroics of two years ago, when they turned around a 3—nil first—leg defeat to knock—out barcelona at anfield. now to tennis and stefanos tsitsipas's clay court season is up and running. he's through to the third round of the monte carlo masters after a straight sets win over the in—form russian aslan karatsev, who'd recently just won his first atp title in dubai. but the fourth seed tsitsipas was just too strong, in the end winning 6—3, 6—4. he'll face eitherjohn millman or christian garin in the last 16. and 19—year—old jannik sinner will face world number one and top seed novak djokovic in the second round on wednesday. the italian, who reached the final at the recent miami masters, beat spain's albert ramos—vinolas 6—3, 6—4.

you can get all the latest sports news at our website — that's bbc.com/sport. but from me, austin halewood, and the rest of the sport team, goodbye. as difficult as lockdown may have been, for some it's been an opportunity to flex their creative muscles. many took up painting, others began writing that novel they'd always had in mind. but if you're a legendary rock star like sir mick jagger, you're only going to express yourself in one way, as the bbc�*s tim allman explains. he was once an �*exile on main st.�* now, he is a legend in lockdown. sir mickjagger, stuck at home like the rest of us, decided to turn his experience into song: eazy sleazy, a tale about zoom calls, tiktok videos

and too much television. it's a transatlantic coproduction made with another rock god of a younger vintage. sirmick said: dave's fulsome response: it's actually been quite a busy period for the rolling stones' lead singer. last year the band launched their first store in london's carnaby street. now, a rocker celebrating a hopeful return to normality. "we are heading back to paradise," he sings. some satisfaction at last! tim allman, bbc news.

80 french officer cadets got some strange assistance when they took part in drills. various combat were reproduced with cadets using robots for reconnaissance and support including the famous boston dynamic spot robot and equipment produced by a french hardware firm. see, we are all going to be replaced sooner or later! residents in florida and the bahamas got an unexpected meteoric visitor! a striking trial of light could be seen by eyewitnesses and security cameras across the sunshine state as the lump of rock bent up state as the lump of rock bent up and disintegrated. i will be backin up and disintegrated. i will be back in a moment with all the top business stories including

travel talk. see you in a moment. hello. april so far has been colder and drier than average, and the weather for now is in no mood to change that pattern. so, plenty of dry weather continuing for the next few days, but of course the thing which has got most of us talking is just how chilly it feels. there's more of that to come as well and more of those frosty nights. it is high pressure. whenever you see this, you think, "well, it's dry." however, as we saw on tuesday, there were showers around. and there will still be a few in the day ahead, though most will stay dry after what is another widespread frost to start the day, another hard frost in parts of scotland — down to —6, for example, in the north—east. one or two mist and fog patches. they will clear and we're left with quite bit of sunshine. just some areas of patchy cloud around and, you canjust see it here, one or two showers

developing, more especially towards the western side of the uk. now, the winds for the most part are light, but look at the arrows here pushing in towards that north sea coast of scotland and down the eastern side of england, coming in from the sea, which is quite chilly at this time of year, and that's why these temperatures are just showing seven, eight or nine celsius. so with the onset of that north—easterly breeze, eastern areas will actually be colder, whereas we're 13 in cardiff and plymouth and 13 probably towards western parts of northern ireland. any showers that have popped up will fade away as we get on into the evening. we have another largely clear and cold night to come into thursday morning, and again one or two mist and fog patches around. and there will be another widespread frost, although we're not expecting it to be quite as hard as it's been over recent nights. how's thursday shaping up? most dry with sunny spells, but on that north—easterly breeze, we will bring in a few showers to parts of eastern england, into the southeast, perhaps the east midlands

as well. if anything, that breeze will be a touch fresher, too. for the most part, though, elsewhere, the winds are light. there is warmth in the sunshine if you get some of that. you certainly feel it as temperatures, away from the chilly east, will be close to the average for the time of year. big picture going friday into the weekend, there are weather fronts trying to move in from the atlantic towards northern ireland and scotland, initially perhaps just bringing a bit more cloud. but deeper on into the weekend, more especially on sunday, there is a chance that, here, we could see a bit of rain, whereas elsewhere it stays dry.

this is bbc news with the latest business headlines for viewers in the uk and around the world. aviation bosses react to the uk government's internation travel plans. we speak to the boss of trivago to find out if he gives it the green light? the boss of toshiba steps down, after controversy over a $20 billion buyout bid from his former employer, cvc capital partners. and have you heard of loot boxes — where gamers only find out what they've bought after spending their money. critics warn it's acclimatising children to gambling.