this is bbc news with the latest headlines for viewers in the uk and around the world. india's health care system buckles as a record surge in covid cases puts pressure on hospital beds and life—saving supplies. if oxygen runs out, there is no leeway for many patients. there is no leeway, they will die. rescue teams race to find an indonesian submarine with 53 people on board missing off the coast of bali. a new malaria vaccine is hailed as a potential breakthrough as early trials prove it to be 77% effective. the fatal stabbing of a policewoman near paris is investigated as a terrorist offence. the architect of britain's brexit policy, dominic cummings,

turns on his former ally — the prime minister, borisjohnson — saying he lacks integrity. we start in india, where the situation is critical as the health care system struggles to cope with a surge in coronavirus patients. for two days running, the country has seen a record number of new cases. in the past 2a hours alone, 330,000 new infections. hospitals are full, and oxygen is in short supply. 0ur delhi correspondent yogita limaye got access to the emergency ward of one hospital. her report contains distressing scenes from the start.

the front line — an emergency room in a covid hospital, just about standing under the weight of an unfolding disaster. a patient who's hardly breathing is brought in. as nurses try to get him to respond, there's another person, even more critical. this woman rushes to help. so many like her are putting in all they can. they couldn't revive him. to get past the shortage of beds, they've packed in stretchers, wheelchairs, as many as they can. but the first line of treatment against covid—i9 is oxygen. and they've almost run out. at this point, there was just one

hour of supply left. the staff knows how many lives hang in the balance. people are being turned away, but they don't know where they'll find oxygen or a bed. manura bibi was taken in for a short while to stabilise her. "we've already been to five hospitals. "where will poor people like us go?", her nephew asks. but this hospital is so on the brink, they have to leave. the intensive care unit is full, too. there are next to no icu beds in a city of 20 million. these are patients in a critical condition. it's unthinkable, unimaginable, that one would think of them as better off in any way, but it's the reality

of what we're seeing in india. people in an icu have won the first battle, to be here. between seeing his patients, the doctor, constantly on calls. back—up, another couple of hours. so, we are struggling, we are struggling... he's desperately trying to get more oxygen. we are running out of oxygen. the whole country is running out of oxygen, 0k? the city is, we are, everybody is, ok? so, please focus on that, please. you're doing a fantastic job otherwise, 0k? please. 0k, all of you remember that. if oxygen runs out, there is no leeway for many patients. there is no leeway, they will die. day after day, the staff work here, knowing full well that if their families get sick, even they will struggle to find medical care. there is helplessness and anger. the government in some ways has failed in estimating

what was going to happen, the needs that would arise if the numbers started rising. there was a sense of preparation for the earlier surge that seems to have disappeared in between. and they did things which were totally unacceptable, allowing large, huge gatherings, which was totally unacceptable. they believed we had vanquished the virus. some oxygen arrives a bit later, but it can only last a few hours. then the struggle begins again. yogita limaye, bbc news, delhi. dr deepti gurdasani, clinical epidemiologist and senior lecturer at queen mary's university london, joins me now. thank you forjoining us here on bbc news. the first question i would really like to address this to what extent do you think this new variant is behind this surge in cases? i mean, i think there is a link to the

new variant possibly because a lot of the population that we are seeing these surges and are thought to have had a high level of exposure to the virus. in delhi for example about 50-50% of virus. in delhi for example about 50—50% of people had antibodies but this is not equally disputed some communities will have the more than others but to seek a rapid rise of cases in a short period of time in communities that we think had antibodies but this is not equally disputed as some communities will have the more than others but deceived a rapid rise of cases in a short period of time in communities that we think have been exposed widely is really unusual. it’s that we think have been exposed widely is really unusual. it's been described as _ widely is really unusual. it's been described as more _ widely is really unusual. it's been described as more contagious. i widely is really unusual. it's been i described as more contagious. what else can you tell us about itmore deadly? we else can you tell us about itmore deadl ? ~ ., �* ~ ., else can you tell us about itmore deadl? .,�* ~ ., , else can you tell us about itmore deadl? «my ~., deadly? we don't know yet. what would be more _ deadly? we don't know yet. what would be more transmissible - deadly? we don't know yet. what would be more transmissible but| would be more transmissible but again we don't have data on that. we can see is that it is written in frequency particularly in places like maharashtra where places have jumped at the same time. it also has a mutation, with the so—called south african and manaus variant that we associate with possible reduction in vaccine efficacy. we don't know if this is the case yet but it's something that needs to be explored and i might be one of the explanation for why we are seeing

cases rights even in populations that may have been exposed before. do you think the situation could have been avoided? i do you think the situation could have been avoided?— do you think the situation could have been avoided? i think there's no doubt he _ have been avoided? i think there's no doubt he could _ have been avoided? i think there's no doubt he could have _ have been avoided? i think there's no doubt he could have been - have been avoided? i think there's . no doubt he could have been avoided. we have seen cases in india rising since the february in many parts of india since late february, and we know with this financial rises that when cases start doubling in a week's time, what is going to happen. it's a very creditable trajectory so it is very hard to understand why the government did not ask over the last six weeks and rather large gatherings were allowed, election rallies continue and lock downs in many parts of india and really been instituted in the last week. you india and really been instituted in the last week.— india and really been instituted in the last week. ., ., , the last week. you said the worrying word there. — the last week. you said the worrying word there, exponential. _ the last week. you said the worrying word there, exponential. so - the last week. you said the worrying word there, exponential. so i - word there, exponential. so i presume then that we have not seen the peak in cases? ida. presume then that we have not seen the peak in cases?— presume then that we have not seen the peak in cases? no, sadly not. we not seen the — the peak in cases? no, sadly not. we not seen the peak _ the peak in cases? no, sadly not. we not seen the peak in _ the peak in cases? no, sadly not. we not seen the peak in cases _ the peak in cases? no, sadly not. we not seen the peak in cases and - the peak in cases? no, sadly not. we not seen the peak in cases and wouldj not seen the peak in cases and would not seen the peak in cases and would not send the peak in death. and of the deaths we are seeing which are huge underestimates reflect cases three weeks ago probably. so it's very unlikely that deaths will be

speaking anytime soon. there will probably continue to rise at least for the next 3—4 weeks and probably even longer if it takes is —— cases longer to peak. and there is no indication now of this plateauing out. ~ ., indication now of this plateauing out. ~ . ., , indication now of this plateauing out. ~ . , , out. what about vaccines very cuickl . out. what about vaccines very quickly- when _ out. what about vaccines very quickly. when i— out. what about vaccines very quickly. when i ask _ out. what about vaccines very quickly. when i ask you - out. what about vaccines very quickly. when i ask you aboutj out. what about vaccines very - quickly. when i ask you about the variance, you pointed out there is stuff that we just don't know yet. so the obvious question is there is a shortage of vaccines in india but i want to know how the roll—out is going and if we know if vaccines are actually effective against this new variant. 50 actually effective against this new variant. ., �* ~ ., variant. so we don't know where -- whether the — variant. so we don't know where -- whether the vaccines _ variant. so we don't know where -- whether the vaccines are _ variant. so we don't know where -- whether the vaccines are effective i whether the vaccines are effective but generally vaccines intended to protect at least to get cyr to beard disease with variance so far but not always the case. so we hope that they will be effective some anybody was offered a vaccine should definitely take it. in terms of roll—out, about 130 many people have received a vaccine which is about less than 2% of the population of india and there are shortages of

vaccines although vaccines have been opened up to younger age groups as well. there is also a huge problem with cost because example 18 have a 45 euros the cost of vaccine which is quite high which also creates inequities in distribution so i think there are issues with supply right now when there are issues with cost and of course we don't know about the effectiveness of this point in time. everybody should take the precautions that they need to take in any case with masks come distancing, etc.— take in any case with masks come distancing, etc. very quickly under cinnabar that _ distancing, etc. very quickly under cinnabar that anyone _ distancing, etc. very quickly under cinnabar that anyone aged - distancing, etc. very quickly under cinnabar that anyone aged over . distancing, etc. very quickly under cinnabar that anyone aged over 18| distancing, etc. very quickly under i cinnabar that anyone aged over 18 is being invited to registerfor a vaccine. does india have to deal with a vaccine hesitancy at all? yes. there's been a lot of vaccine hesitancy in general and a lot related unfortunately to the way the government managed vaccine relapse. so for several one of the vaccines was rolled out prior to completion of phase three trials and prior to data on the trials even today we don't have published data on trials as it has just been released by a press release. so i think there

needs to be a lot more transparency around this and a lot more engaged with the public around trust which has not happened so far.- has not happened so far. doctor, thank you — has not happened so far. doctor, thank you very — has not happened so far. doctor, thank you very much _ has not happened so far. doctor, thank you very much for - has not happened so far. doctor, thank you very much for that, - has not happened so far. doctor, i thank you very much for that, thank you. there are fears oxygen supplies have run out on an indonesian submarine that went missing off the coast of bali on wednesday. search teams from a number of countries are trying to find the vessel, which has 53 people on board. the indonesian authorities previously warned it had enough oxygen to last until the early hours of saturday morning. but there's still no sign of the submarine. it's thought it may have sunk to a level that it cannot withstand. i'm joined now by bryan clark, a senior fellow at the hudson institute and former us navy officer. he's been following the international rescue efforts. what do we know about the submarine and this particular

what is your gut instinct about this summary in the fate of those on board? ., , ., , summary in the fate of those on board? ~' , . , ,., board? likely at this point the submarine _ board? likely at this point the submarine is _ board? likely at this point the submarine is lost _ board? likely at this point the submarine is lost in _ board? likely at this point the submarine is lost in the i board? likely at this point the submarine is lost in the crew. board? likely at this point the i submarine is lost in the crew would likely incapacitated or potentially lost. normally at this point in a submarine rescue effort, you would have tried to hear some noise from a submarine to indicate the people inside are trying to be found and that they are active and still alive. we are not getting any of that right now. the area in which they are searching for the summary is a relatively large area but is confined enough that with passive sonar that should be able to detect some noise coming from the summary and we have not heard anything yet. what does that tell you then if you are not getting a solar read back? in terms of challenges emma what are they fighting and facing?— they fighting and facing? right, so they fighting and facing? right, so the searchers _ they fighting and facing? right, so the searchers are _ they fighting and facing? right, so the searchers are going _ they fighting and facing? right, so the searchers are going to - they fighting and facing? right, so the searchers are going to be i they fighting and facing? right, so i the searchers are going to be having to look for the submarine using essentially active sonar searches along the bottom like bottom surveys we have done for previous airline disasters. as you know from those, it has taken weeks or months to find any debris on the sea floor so it's any debris on the sea floor so it's a very hard problem. so if the

submarine is not making noise, they are forced into that approach. also the crew only had enough oxygen to get them through the late hours today and also the problem of carbon dioxide removal is an issue as well. so between the measures they have on board as well if the back—up measures they have got with chemical removal systems or oxygenation systems, the probably will have run out of oxygen by the end of today. i wanted you could just tell us how it could have gotten lost because that might help and try to work out what went wrong. what do you know about that? ,, ., , ~ went wrong. what do you know about that? , ~ ., , ,., that? sounds like there was some kind of power— that? sounds like there was some kind of power loss _ that? sounds like there was some kind of power loss on _ that? sounds like there was some kind of power loss on the - that? sounds like there was some i kind of power loss on the submarine that would likely result in a loss of control of the submarine and there are lots of systems in place to the summer and could have used them to lose all power, doing an emergency blow of the ballast tanks to get to the surface to be rescued. so they must�*ve been some other, waiting casualty so in addition to the power loss he must�*ve suffered some kind of flooding or a fire perhaps that cost the crew to be

unable to activate the emergency blow and get back to the surface. so it is unusual and hard to tell what combination of factors led to this submarine being lost or at least sunk to some point that they cannot find it. it is probably some combination of flooding, fire and a power loss that's happened on board. when you expect to be made on this? i dissipate by tomorrow there will probably have made a decision to transition from the rescue operation into a recovery operation. at this point, since they have got no indication the crew is alive or have been able to —— not able to find the summary in the places where it could be able to be rescued by the public to make that transition. at 2000 feet which is the death of the water here, that summary will not be able to survive because he would be crushed at around 1000 feet so likely would have broken up and also the summer and rescue efforts would require the summary to be intact and at least positioned up right on the sea floor and it may not be the case either. so that will be a comment to

make to tradition to recovery operations later tonight or early tomorrow. . ., operations later tonight or early tomorrow. ., ,, , ., operations later tonight or early tomorrow— operations later tonight or early tomorrow. ., ,, , ., , . ., tomorrow. thank you very much for that. tomorrow. thank you very much for that- you're — tomorrow. thank you very much for that. you're welcome, _ tomorrow. thank you very much for that. you're welcome, thank i tomorrow. thank you very much for that. you're welcome, thank you. i a malaria vaccine has proved to be 77% effective in early trials and could be a major breakthrough against the disease. a50 children in burkina faso participated in the trial. the next stage will increase the sample to a800 children. malaria kills at least 400,000 people a year, mostly children in sub—saharan africa. but despite many vaccines being trialled over the years, this is the first to meet the required target. the bbc�*s rhoda 0dhiambo reports. the news out of this lab could save thousands of lives. for the past year, researchers at this institute outside of 0uagadougou have been testing r21, a potential vaccine

against malaria. it is amazing, because in this world, we have never seen a malaria vaccine that is so high—level. so, for me, i think this is really the success story of my life. burkina faso was chosen for the study because of the high number of malaria cases, especially among children. other african countries face similar challenges. there is a lot of investment in malaria control in africa, in burkina faso, everywhere, but so far, cases are still high. and, of course, with the vaccine, that can reduce these cases by 70%. of course, we will be very close to end the malaria in africa. malaria is one of the leading causes

of child mortality in africa, and more than 400,000 people worldwide died from the disease in 2019. african countries and international donors have invested billions into eradicating it, but recent progress has stalled. a previous vaccine released in 2015 took nearly 30 years to develop and is less than 50% effective. r21 is potentially much more effective and could also be cheaper. the cost of a single dose will be pegged at less than $3 us. the new vaccine was developed in conjunction with thejenner institute at oxford university. the team there will move to phase three trials next. thousands of people in burkina faso, mali, kenya and tanzania will participate. traditionally, it would take two or three or four or even five years to get approval after you start your phase three trial. during that time, we know hundreds of thousands of african children

are going to die every year. is there therefore not a case for an emergency use approval of a malaria vaccine in the same way that african regulators have approved emergency use authorisation of the covid vaccines? if approved, roll—out could begin quickly. the world's largest vaccine manufacturer, the serum institute of india, has already agreed to manufacture 200 million doses. it could have a huge impact on malaria across the world. rhoda 0dhiambo, bbc news, nairobi. the french national anti—terrorist prosecutor has taken charge of an inquiry into the fatal stabbing of a policewoman near paris. police officers shot dead the tunisian attacker after he stabbed her in the throat at the entrance of a police station in rambouillet, south—west of the capital. paying tribute to the 49—year—old officer, the prime minister, jean castex, said france had lost one of its everyday heroines

to a barbaric and cowardly act. translation: my first thoughts go to the family of this official - and to all those close to her. i came to the scene immediately with the interior minister to give all our support to the officers and officials of the rambouillet police station, who as you can imagine, have been very hard hit by what's happened. i would like to pay a great tribute to the police officers who managed to immediately neutralise the perpetrator. i want to say to all french people that our determination to fight against terrorism in all its forms is more intact than ever. stay with us on bbc news. still to come, from closest ally to bitter critic — dominic cummings launches an explosive attack on uk leader borisjohnson.

music. the stars and stripes at half—mast outside columbine high — the school sealed off, the bodies of the dead still inside. i never thought that they would actually go through with it. one of the most successful singer—songwriters of all time, the american pop star prince, has died at the age of 57. ijust couldn't believe it. i didn't believe it. he wasjust here saturday. for millions of americans, the death of richard nixon in a new york hospital has meant conflicting emotions — a national day of mourning next wednesday sitting somehow uneasily with the abiding memories of the shame of watergate. and lift—off of the space shuttle discovery, with the hubble space telescope, our window on the universe.

this is bbc news. the latest headlines — india's health care system buckles as a record surge in covid cases puts pressure on hospital beds. rescuers have just hours to find a missing indonesian submarine and its 53 crew members before oxygen runs out. us presidentjoe biden has hailed the carbon—cutting pledges made at the global climate summit, saying that half the world was now committed to the progress needed to limit global warming to 1.5 degrees. however, mr biden emphasised that leaders must live up to their commitments. as he put it, anything else was "just hot air". let's hear some of what he said. we've made great progress in my view so far. i'm grateful to all the leaders who have announced new commitments to help us meet the existential threat of climate change. this summit is a start,

a start of a road that will take us to glasgow for the un climate change conference in november, where we're going to make these commitments real, putting all of our nations on a path to a secure, prosperous and sustainable future. the british socialite ghislaine maxwell has appeared in court in new york on new charges of sex trafficking. it's herfirst appearance in person since her arrest last year. she's accused of helping the convicted paedophile jeffrey epstein recruit, groom and sexually abuse girls. ms maxwell pleaded not guilty. her lawyer said ms maxwell was being treated "horribly" injail, but was looking forward to her trial. the british prime minister's former top adviser, dominic cummings, has launched an attack on his old boss, borisjohnson. dominic cummings, who was one of the architects of brexit, said it was sad to see

the prime minister fall so far below the standards of competence and integrity the country deserves. mr cummings made the comments after he was accused by a government source of leaking damaging text messages between mrjohnson and a businessman, which he denies. 0ur political correspondent greg dawson explains why this story is so explosive and potentially damaging for the british prime minister. this is a denial, but it's a fact that it's such an explosive denial and a personal attack on the prime minister and his office. these two men worked closely together for several years. let's just go through the denial first of all regarding the leak of text messages between borisjohnson and sirjames dyson. this was relating to james dyson's staff coming to the uk to produce ventilators. the bbc reported on that and the information gleaned from those text messages. today, dominic cummings has denied he was part of that leak. he said he does have text messages

relating to dyson's business with the government, but it's much more related to the ventilators and to covid policy. it has nothing to do with the tax issues that the bbc has been reporting on earlier this week. now, there's also a second leaked story that dominic cummings touches on. cast your mind back to november last year, and there was leaked information that borisjohnson was on the verge of announcing a second lockdown in england. that led downing street to launch an inquiry into who was behind that leak. now, mr cummings says he was cleared of that along with the director of communications at the time, but he goes on to say in this blog that the prime minister doesn't want or didn't want an inquiry into the leak because it could cause him great personal difficulty. there is a third issue that dominic cummings raises in this blog, and that is the issue of the renovation of the downing street flat where he resides with his partner, carrie symonds. now, it's been reported for months that carrie symonds wasn't happy

with the decor in this flat and that she hired an expensive interior designer. dominic cummings is claiming that the prime minister planned to have donors secretly pay for the renovation of the flat. mr cummings said the pm stopped talking to him about the issue because dominic cummings told it to him straight. and i am quoting from the blog saying the plans were "unethical, foolish, possibly illegal and almost certainly broke the rules on proper disclosure of political donations if conducted in the way he intended". now, earliertoday, before this statement was released, the government said that the costs of the wider refurbishment of that flat in downing street had been met by the prime minister personally. the reality tv star and transgender activist caitlyn jenner said she intends to run for governor of the us state of california. in a statement posted on social media, the star of the tv series keeping up with the kardashians said she would provide californians with a road map back to prosperity.

the 71—year—old long—time republican is hoping to unseat the democratic governor, gavin newsom, who is facing a recall bid over charges of mishandling the state's coronavirus response. and before we go tonight, rocket company spacex has sent four astronauts bound for the international space station into orbit. lift—off was early this morning. two, one, zero, ignition and lift off! at the kennedy space center in florida, a successful launch. the spacex crew dragon capsule is carrying two american,

one japanese and one french astronaut to the international space station. it's a continuation of the effort by the american space agency nasa to turn over to the private sector the business of taking people into low—earth orbit. hello. wales reached 21 degrees on friday. scotland had its highest temperature of the year so far at 20. and after a warm, sunny start to the weekend, it will turn a little cooler and cloudier as the weekend goes on, especially in eastern areas. it's still largely dry throughout with high pressure here, but the flow of air around that as the weekend goes on will become more of a pronounced easterly across the uk, with that cooler air starting to move in and more cloud, especially by sunday and especially in the east, as we'll see in a moment. another chilly morning to kick off the weekend, but not as cold as recent mornings, though still there will be a patchy, mainly rural frost around

and temperatures head up in the morning sunshine quite quickly. 0nce any early mist and fog patches clear away from eastern england, there will be a bit of patchy cloud for parts of scotland, especially in the east and into north east england. but for most areas, it's a day of unbroken sunshine once again. shetland, though, turning cloudy with a chance of a little light rain. it will be a cooler day along north sea coasts with a breeze off the sea, but in western areas of the sunshine, every bit as warm as friday, 19, perhaps 20 degrees again. and there will be moderate to high pollen levels and moderate to high uv as well. now, we are expecting more cloud to arrive as we go after dark on saturday night. just filtering in here from the east, particularly into parts of england and wales. there could be a few mist and fog patches around, too. although temperatures again are a little bit higher as we start sunday morning, still the odd touch of frost in the countryside can't be ruled out. and then on sunday, don't be surprised to have some cloud, particularly across parts of england and wales and patchy cloud in scotland breaking to allow sunny spells. though parts of eastern england

could stay rather cloudy with a chance of a light shower and an isolated heavy shower in highland scotland can't be ruled out. more of us noticing that easterly breeze, quite gusty through the channel, channel islands and south west england as it's been for the past few days. and quite chilly along that north sea coast, cooler elsewhere but still up to 17 in western counties of northern ireland. into next week, and high pressure giving way to low pressure and that brings a chance anyway of a little rain moving southwards monday into tuesday. doesn't look like it's going to amount to very much, at the start of a week which while likely it'll be cooler than average once again with a chance again for a few showers, but not enough to stop this being one of the driest aprils we've known.

this is bbc world news. the headlines. india's hospitals are reporting dangerously low oxygen levels and no empty beds as coronavirus cases reach record highs. there have been 2,263 deaths in the past 24 hours. the french president, emmanuel macron, has said france will never yield to islamist terrorism. he was speaking after a female officer was stabbed to death inside a police station near paris. there are fears oxygen supplies have run out on an indonesian submarine that went missing off the coast of bali on wednesday. search teams from a number of countries are trying to find the vessel, which has 53 people on board. a new malaria vaccine developed by researchers in britain, has been 77% effective in stopping infection in early clinical trials. the drug was tested on 450 babies and toddlers from burkina faso.