hello this is bbc news. the headlines: people in areas where the indian variant of coronavirus is spreading are urged to get a covid vaccination. testing and vaccination are really important measures that we have in the tool box for controlling outbreaks. the tool box for controlling outbreaks. a tower block in gaza, housing the offices of the associated press and aljazeera news outlets, has collapsed after being hit by an israeli airstrike.

how hamas was using that building and it was part of the hamas war machine. meanwhile in london thousands of pro—palestinian protesters have marched to the gates of the israeli embassy. wreath laying services have been held across the uk and around the world — to mark the centenary of the royal british legion. leicester city have beaten chelsea at the english football association cup final at wembley stadium in london. 21,000 fans attended the match, as part of the government's pilot scheme to test the safety of mass events.

welcome to click. we're outside again. great to see you in the flesh again. and you. i can't believe it. no matter how long it is since i've seen people, as soon as i see friends and family again, it's like we've never been apart! yep, too right. although this time round, i think everybody�*s really gone for it with their hair, since the hairdresser�*s reopened. i don't know what you're talking about. i tell you what, though, it is true that we've spent so much time apart in the last year that when we do see people in the reals, you really notice the difference. my parents can't believe how much my kids have grown since they last saw them. and that's kind of what we're talking about today — the fact that even though we're all getting older on the outside, there are ways to stay younger on the inside by hacking our health. now, if you're anything like me you may be using an activity tracker to log your exercise. but at the moment, we're just

scratching the surface of the data that's hidden inside our bodies. aside from exercise, there's genetics, sleep, diet — so many other lifestyle factors that can really make a difference. and there are some people who believe that if we can unlock this complete picture of our health, then we might be able to stop or even reverse the ageing process. instead of talking about lifespan, we're now talking about health span — the desire to stay as fit and healthy as possible for as long as possible, even though the years are ticking on by. though the years have been clocking up on this fine frame, my chronological age, therefore, is 47 but there is something else called a biological age, which is the age that you are inside. now, i've had that checked. have a guess at the results. um, 21? now she is just is taking the mickey. let's find out. king's genomics centre — part of a world—leading research university in london, and where i'm discovering

the secrets in my dna. so james, a few weeks ago, i spat into a tube and posted it to you. you're welcome. my epigenetic age is... 44.1. not too bad! yeah, so your biological age, it's basically seeing how your cells are ageing, the various things such as your diet, how much stress you're under, how much sleep you're getting. it's a nice barometer to predict your future health. my genes didn'tjust deliver one age though. muhdo uses artificial intelligence to trawl through 850,000 different biological markers to deliver different ages for different body parts. for example, my eye age is 53 but my hearing age is 43.7. and the key thing that scientists now know is that although your genes do set you on your life's course, they are not set in stone. your genetics will underpin most of your predispositions, so they'll give you a positive or a negative. whether that actually comes into fruition is up to you, really, because you flick

on these genes with your lifestyle and environment. the company has run tests with some 2,500 people, but more research will be needed to take some of its advice from anecdotal evidence to scientific fact. if you want to reduce your memory age then dancing is quite good, apparently. i've got old eyes? carrots. we're always being told that carrots are quite good for us and that's actually true. have you ever seen a rabbit wearing glasses? now, whether you go the full bugs bunny or whether you samba your way to better brain health, this is about building a personalised picture of health. what works for me will not work for you and vice—versa, but we'll be able to actually pinpoint what your diet needs to look like, how much stress you can be exposed to, what pharmaceuticals you can and cannot take. we can pinpoint them exactly, specifically, to you. ok, i'm going to try to go

to bed maybe an hour earlier. i'm going to go for a walk in the morning. what's that going to do to my biological age? so it gamifies genetics. muhdo has partnered with king's college london, where experts say that our biological age isn't fixed. and in fact, it doesn't have to progress in just one direction. the ageing, or biological score, is malleable. the risk of getting an age—related disease, such as diabetes, can be increased or decreased based on your lifestyle. and that's led some people who i've met in the past to suggest that we might be able to stop the ageing process altogether. most notably aubrey de gray, who famously suggested that within the next century, we might be able to extend our lifespan by hundreds of years. we develop ways at the molecular and cellular level

to repair the damage that the body does to itself throughout life. there's a lot of talk about stopping the ageing process or even reversing the ageing process. towards the end of my lifetime, probably, i think we can have immortality, if you're willing to pay for it. now, genetic trackers are not the only testing tool to help counter ageing. another company has analysed things called glycans in my blood. these have given me an idea of the age of my immune system. in this case, we're looking at sugars on immunoglobulin, which is the most abundant antibodies, so it's a key weapon in our arsenal in our immune system. now, you've measured my biological age at 20. i was flattered for a few seconds and i thought "no, that can't be right." a 40— 50—year—old can have a much younger glycan age, and that's really good for you. if you're talking about grey hairs or skin, then i would use a different clock for that. now, all of these different numbers attached to different

bits of my body are leading me to think that we are using the wrong word here. a biological score would be a more sensible way of thinking about your age. and the fact that you can change your biological score is very positive. it's not all doom and gloom — "i'm set to be old and decrepit at a certain time in my life". this can be slowed down or even reversed. whatever your personal measurement is, scores like this could flag impending ill—health with studies spotting that a change in your glycans could signal coming arthritis, cardiovascular disease or diabetes up to a decade before onset. 0ur dataset is really good, so it's 150,000 people that some which we've followed for 20—30 years. it's a warning where you can still do something about it

and prevent it. and just a small warning — a good score now doesn't give you a free pass to a healthy future. so it changes — it's not something that's going to stay the same throughout. and this is a way for you to know if something particularly works for you. when it comes to those living with dementia, a new brain analysis tool could help provide earlier diagnosis and even, potentially, assist in creating better drugs to help. jen copestake�*s been finding out more. using tools to monitor patients remotely has become more pressing since the coronavirus pandemic. a collaborative study called radar—ad aims to help see how alzheimer's patients can be monitored in new and improved ways. one of the assessment tools in the study is an

augmented reality app called altoida, which is showing spatial navigation and memory function. it works by asking the person to choose three virtual objects and place them around a room. they then have to remember where they placed the objects, what order it was and what the actual object was. device: go to where you want to place the heart. _ as well as this memory test, off—the—shelf technology like fitbits and cameras are being repurposed too. this is a medallion camera that the participant wears around their neck, and it captures digital photographs on a cyclic basis. so it doesn't take constant footage but it does provide valuable contextual information. while alzheimer's is not a movement disorder, gait analysis trackers can gather useful data points. two go on the instep of each foot and then the final one goes on the right hip. we do know that as cognitive decline worsens it does cause changes in walking patterns, so they might suddenly change direction or stop because they're not sure where they are, they've realised they're going in the wrong direction. in the uk, over 850,000 people are living with dementia. do you want me to run through

the instructions again briefly? normally, dementia is diagnosed through a series of paper memory tests, in person, with a doctor. but these tests lack nuance and can be learned by the patient over time. john hart and his partner richard finder are here in crowborough hospital in east sussex testing a new app called cognetivity which aims to prevent this. so if you see an animal, you're clicking on the right side of the screen. john's recently been diagnosed with alzheimer's disease. there were many verbal tests and number tests. i'm used to people respecting me and not asking silly questions. to be in that position i think was difficult at first, really. instead of lists of questions, the app flashes rapid images. each picture is either an image of an animal or not an animal. the user indicates their choice by pressing the left or right side of the ipad screen. as it cannot be learned, the test gives an objective

analysis of the patient�*s neurological state, even when repeated multiple times. what the test does is use what we call rapid visual categorisation. and it's really looking to see how quickly the brain can process complicated information. is it always an animal or a landscape? it's always an animal or not an animal. and that's actually a very important aspect of the test because the human brain is very finely tuned to be able to pick up on animal stimuli. the use of this will make it easier to assess larger numbers of patients, but more importantly, it speeds the referral process and results in early diagnosis and early treatment for patients which is exceptionally important. another possible way to remotely measure cognitive function is through brainwave analysis. headsets like this one from belfast brainwave bank could be used at home to track changes in brain activity. the eeg scanner connects with a smartphone app to record and analyse data. as subtle changes in brain activity can be observed

up to ten years before symptoms of dementia present, these technologies could all be vital in early diagnosis. and the more individual data that's collected can also feed into bespoke treatment plans and drug development. that's it for the short version of this week's click. the full—length version is available to watch on iplayer. well worth a watch because i've seen it and ifeel youngerjust from watching it. do you? i'm actually feeling like i should have been doing some of those anti—ageing things that i haven't been. i'm hoping it's not too late. come on, if you haven't been doing them, no—one has! that is all we've got time for in this short version, i'm afraid. as ever, you can find the team on social media, on youtube, instagram, facebook and twitter, @bbcclick. thanks for watching and we'll see you soon. bye— bye.

hello and welcome to sportsday — i'm gavin ramjaun. fans are back for the fa cup final — and they almost had something to celebrate at half time. we'll have the latest from chelsea against leicester. an invincible season — rangers see through the whole scottish premiership unbeaten — after thrashing aberdeen in their final game at ibrox. and tom daley and matthew lee take gold at the european diving championships — but they're stil not satisfied.

hello and welcome to sportsday. hello — and welcome to the programme. where leicester city have made history, winning a first ever fa cup. they beat chelsea in the final at wembley. in front 20,000 fans who got see it inside the ground. it's a special win for the club, and manager brendan rodgers. and we cross live now, to wembley, and join our natalie pirks. — this was a fitting final for the fans to be part of again. as you say, for brendan rodgers, his seventh win in seven finals. another momentous day in the history of this football club. they have been to four fa cup finals in the past in the last one was 52 years ago. they have never won it and finally and

how because the goal that