this is bbc news — these are the latest headlines in the uk and around the world. just five months old and making history — a baby with a devastating genetic disorder has become one of the first patients to get a potentially life—saving gene therapy in the uk. the heads of global bodies including the world health organisation urge the g7 to give extra vaccines to third world countries, to halt the spread of variants. peru announces the real number of coronavirus deaths is more than double the figure previously reported. 180,000 people are said to have died. in england, as thousands rush for a jab in west london, there are further warnings that a rise in case numbers could delay the lifting of all

restrictions later this month. i think at the moment, the data does suggest that we need to be cautious, we mustn't lose all the gains that have been made over the last few months by premature and hasty, non—evidence—based loosening of restrictions. how will you be affected if the 21st june unlocking is pushed back? i'd love to hearfrom you this morning — you can tweet me @annita—mcveigh and using the hashtag #bbcyourquestions. london's heathrow airport opens a terminal for passengers arriving from the uk's red list countries. the system is design to keep travellers from high—risk coronavirus destinations from mixing with other arrivals. a two—week delay to birmingham's clean air zone. high—polluting vehicles will be charged to drive into the centre of the english city, but payments won't start today as originally planned. and coming up this hour, naomi 0saka pulls out of the french open saying she's suffered from depression since winning herfirst

grand slam title in 2018. hello and welcome if you re watching in the uk or around the world. a five—month—old boy from london has become one of the first children in the uk to be treated with a ground—breaking new gene therapy. arthur morgan, who has spinal muscular atrophy, is being treated with zolgensma. at a cost of £1.79 million per patient it is the world's most expensive drug. the nhs has negotiated a confidential discount for the treatment, which can increase life expectancy

by as much as a0 years. the development means that potentially dozens of infants could be treated by the nhs. around a0 children are born with the most severe form of the disorder every year. and the sma uk charity says newborns in britain should be screened for sma, as happens in other countries. the charity says early diagnosis and treatment is vital. 0ur medical editor, fergus walsh, explains. this is the world's most expensive medicine. the list price of zolgensma is almost £1.8 million, though the nhs has negotiated a confidential discount, which will enable dozens of affected infants to be treated each year. five—month—old arthur is one of the first to benefit. he has spinal muscular atrophy, sma, a genetic condition which causes progressive muscle weakness. without treatment, those affected rarely live beyond the age of two. arthur is unable to lift his head, and struggles to move his arms and legs, but this single infusion

should prevent further loss of nerve cells. it's been massive, massive ups and downs, but being able to now have the treatment is just going to be a game—changerfor us and give arthur the best possible life he could have. around one in every 10,000 babies is born with spinal muscular atrophy. what is remarkable is that this one—off treatment may permanently stop any further decline in arthur's muscle function. so how does zolgensma work? it contains a healthy copy of a missing orfaulty gene called smn—i. this is inserted into a harmless virus. in the body, the virus delivers the replacement gene into the nucleus of motor neuron cells. this is essential to prevent those cells from gradually dying. the now healthy motor neuron cells start producing the missing smn protein,

which is vital for muscle function. how's arthur? evelina children's hospital in london is one of a handful of centres in the uk which will offer this ground—breaking gene therapy. 20 years ago, a baby born with a severe form of sma would have a very shortened life expectancy. we can now offer treatment that can really alter the outlook for these children. some other infants treated with zolgensma have seen their condition notjust stabilise, but improve. arthur's parents say they know it's not a cure, and they're simply delighted that he's being treated. fergus walsh, bbc news. the british medical association has joined calls for the uk government to delay a decision on lifting all remaining lockdown restrictions which is due to take place in england on 21stjune. some government scientific advisers

continue to warn that while the uk's vaccination programme has been successful, it does not mean the battle against coronavirus is over. they suggest that even a short delay to the government's current road map could have a significant impact on the spread of the virus. world leaders have been told coronavirus vaccines must be shared with poorer nations to prevent richer countries from being hit by imported variants of the virus. in an open letter, the heads of four major global bodies warned of a dangerous gap in the availability of jabs, with low—income nations receiving less than i% of vaccines administered so far. meanwhile the world health organization has announced a new naming system for covid—i9 variants using letters of the greek alphabet. global health leaders say the move is to help simplify discussions and also to remove stigma from the names. earlier this month, the indian government criticised the naming of a variant first detected in the country as "the indian variant". the variants are a key concern of those advising against a total easing

of restrictions later this month. here's the chair of the british medical association, dr chaand nagpaul. when you look at the conditions for coming out of...the road map conditions, one of those criteria was to make sure there were no concerns about new variants. so i think, at the moment, the data does suggest that we need to be cautious. we mustn't lose all the gains that we've made in the last few months by premature and hasty, non—evidence based loosening of restrictions. malaysia has begun a tough nationwide lockdown to curb a surge in coronavirus infections. it's the latest country in south east asia to strengthen restrictions as more transmissible variants of the virus sweep the region, where vaccination rates remain low. from tuesday, only essential businesses such as supermarkets and clinics can open, people can only go out for necessities, and most schools are closed. almost half of the country's 2,800 confirmed covid deaths since the pandemic began

occurred last month. malaysia has reported more than 7,000 new infections in the past 2a hours. 0ur south east asia correspondent jonathan head explains why malaysia has to take drastic actions having handled the virus comparitely efficiently earlier in the pandemic. better than certainly the rest of the world but that is applied to the whole of this region, where i am in thailand also did remarkably well last year in keeping covid numbers so low and effectively pushed it down to zero. now, malaysia didn't do that well but they were still able to have quite short lockdowns, open up the economy quite a bit, their health system was never threatened. all these countries, and it is happening in thailand too, are now facing much faster rises in covid numbers. to give you an idea, malaysia's total number of infections has risen by five—fold since the start of the year. it saw 1,000 deaths last year,

again, not big compared to some other countries but much bigger than they are used to, and they are at the stage now where their health systems are threatened, their intensive care units are near capacity. this lockdown in malaysia, it is a strict lockdown, they have a very strict what they call movement control order, it means people simply can't travel very far from their own homes, they are only allowing two people to leave only for essential things they need. most essential services will stay open but any kind of public activities, aside from basic services, are being shut down. the government was reluctant to do it, as all governments are, because of the huge impact on the economy. it said only two weeks but the way these numbers are going up and the fact you have got much more infectious variants of the disease spells real trouble and the real reason is in malaysia, here in thailand, in vietnam which had one of the best records of all last year, none of these countries have been able to get their vaccine programme going. malaysia has only vaccinated around, fully vaccinated around 3.5% of the population and they are struggling, as many countries are, to get vaccines, so they don't have vaccination as an option for bringing these infections down at the moment.

they have got to use these strict lockdowns and they are facing much bigger numbers than they used to. they did so well last year. the highest daily rate we had in thailand last year was 188 cases in one day, and that was exceptional. we are now getting thousands in a day, 3,000 to 4,000. those numbers mean that the methods they have used in these countries, which is mostly very good contact tracing with short lockdowns, may not work this time, and it is going to take them a long time to get the vaccines they need to vaccinate sufficient portions of their population that that will have an impact on the infection rates. we don't think they are going to be reaching levels where you will see an impact on the infection rates of vaccination until the end of the year, so you could see much longer lockdowns. and in all these countries, there are lots of people who fall between the cracks, who don't have stable jobs, they don't get a lot of government support, large numbers people in the informal economy need to get out, they can't cope with these restrictions, so the dilemmas facing the governments of this region,

which were able to deal with covid with just short lockdowns last year, they are much bigger dilemmas now because the lockdowns may have to be longer, there may need to be more of them, the effects on the economies are going to be absolutely devastating. peru has announced the country's real number of coronavirus deaths is more than double what was previously thought. according to the new official figures, 180,000 people have died of covid in peru. that's now the world's highest death rate per head of population. sara monetta reports. families have been decimated by the coronavirus in peru's capital, lima. the second wave of the pandemic is ravaging the country, and the death toll is rising. on monday, the government announced what most people already knew, that the actual number of covid—related deaths is much higher than previously acknowledged. the prime minister said it was the government's duty to make the revised data public, for transparency�*s sake.

until now, the official statistics had the death toll at slightly over 69,000. the revised data put the number at more than 180,000. for months, frontline doctors and relatives had lamented that official numbers were not reflecting the reality they were living. translation: the dead are being taken out of the hospital every day. people are admitted to the hospital every day and we know nothing. relatives wake up here in the cold and sometimes we don't get the full report, that's the truth. experts say that the discrepancy was mostly due to the fact that a death would be recorded as covid—related only if the patient had been tested. the problem is that peru doesn't test that much, a lot of antibody tests and other quick tests have been used, and sensibility has been very low. the new death toll could help understand better how the virus has spread in the country and how

to prepare for future waves. but for frontline workers, the emergency is now, and they feel like they are losing this battle. translation: our health system does not meet the necessary conditions to care for patients. there has been no government support with oxygen, with intensive care beds. we do not have enough vaccines at the moment. the first line of care has not been reactivated. all this makes us the first country in the world in terms of mortality. a grim record for such a small country. sara monetta, bbc news. world leaders have been told coronavirus vaccines must be shared with poorer nations to prevent richer countries from being hit by imported variants of the virus. in an open letter, the heads of four major global bodies warned of a dangerous gap in the availability of jabs, with low—income nations receiving less than 1% of vaccines administered so far.

they said countries could see fresh lockdowns if people in developing nations are not vaccinated at a faster rate. herejoining me is rob yates, executive director of the centre for universal health at chatham house. thank you very much for your time. really, this appeal is to the richer countries�* sense of self interest? news no totally. and it isjust astonishing that we have got to this point and this isn�*t happening already. since the g7 leaders met in february, 1 million people have died of covid and they�*ve done practically nothing. and likewise the 620 practically nothing. and likewise the g20 leaders have done very little, too. so, as your previous piece said, the emergency is now, and all these falls are ramping up the pressure for the g7 to do something properly now. fire the pressure for the g7 to do something properly now. are you sa in: something properly now. are you saying that _ something properly now. are you saying that all — something properly now. are you saying that all this _ something properly now. are you saying that all this talk _ something properly now. are you saying that all this talk of - something properly now. are you saying that all this talk of vaccine equity is just rhetoric? it is

equity isjust rhetoric? it is tokenistic, _ equity isjust rhetoric? it is tokenistic, i— equity isjust rhetoric? it is tokenistic, i think, - equity isjust rhetoric? it is tokenistic, ithink, a - equity isjust rhetoric? it is tokenistic, ithink, a lot. equity isjust rhetoric? it is tokenistic, ithink, a lot of| equity isjust rhetoric? it 3 tokenistic, i think, a lot of it. you are seeing a lot of vague promises about freeing up vaccines, once we�*ve been vaccinated, and good words, but it is not really being matched up with action. and we are going to be soon sitting on enormous stockpiles of vaccines, and potentially talking about booster vaccines in the uk, so, i would be having my third shot potentially in september. and really, this is outrageous, that this is happening, when frontline health workers in places like peru and malaysia are not being protected. 50. places like peru and malaysia are not being protected.— places like peru and malaysia are not being protected. so, from every ara ument, not being protected. so, from every argument. from _ not being protected. so, from every argument, from the _ not being protected. so, from every argument, from the health, - argument, from the health, scientific, the economic perspective, you�*re saying that it makes sense to get initial doses and then second doses to poorer nations first rather than give wealthier nations booster doses or vaccinate children in those wealthier nations?

niche no absolutely. and it�*s all about saving lives. the priority should be about saving lives. and if we are serious about society and mankind, we should be looking to save as many lives as possible. and it is just not right that my kids would get vaccinated before health workers in india, for example. talk to me about— workers in india, for example. talk to me about the _ workers in india, for example. talk to me about the logistics around this, are there any particular barriers that you can see at the moment to getting extra doses, spare doses, to these countries which just haven�*t managed to make strides with their vaccine rollouts? hot haven't managed to make strides with their vaccine rollouts?— their vaccine rollouts? not really. i think a lot _ their vaccine rollouts? not really. i think a lot of _ their vaccine rollouts? not really. i think a lot of it _ their vaccine rollouts? not really. i think a lot of it has _ their vaccine rollouts? not really. i think a lot of it has been - their vaccine rollouts? not really. i think a lot of it has been made l i think a lot of it has been made about that, but we have seen some countries, a number of african countries, a number of african countries, who have done extremely well, with the amount of vaccines they have had, they have got out to they have had, they have got out to the right people very quickly, countries like rwanda have done that. so, there are mechanisms set

“p that. so, there are mechanisms set up to do this now. you have the covax facility which is designed specifically to do this and to allocate vaccines equitably and fairly. i think much better that than wealthy countries pick who their friends are and then ship a load of vaccines out there, because then you have the potential for a number of countries potentially having to much, and some having none. so this is where you need a multilateral approach and the who i think have been doing a fantastic job of doing this, but we just have not been giving them the resources to do the job properly. not been giving them the resources to do thejob properly. 50. not been giving them the resources to do the job properly.— not been giving them the resources to do the job properly. to do the 'ob properly. so, what can g7 to do the job properly. so, what can g7 leaders, — to do the job properly. so, what can g7 leaders, when _ to do the job properly. so, what can g7 leaders, when they _ to do the job properly. so, what can g7 leaders, when they meet - to do the job properly. so, what can g7 leaders, when they meet next, l to do the job properly. so, what can. g7 leaders, when they meet next, do to really drive this forward? there are three things. _ to really drive this forward? there are three things. and _ to really drive this forward? there are three things. and all- to really drive this forward? there are three things. and all these - are three things. and all these reviews are saying the same thing, so it is not as if they are giving conflicting messages. the first is freeing up lots of vaccines common right now, not waiting until your population is vaccinated, to say to some of these manufacturers, you should be donating into covax, or supplying into covax, immediately. secondly, providing significant

extra funding for covax this year and next year, and the imf are coming up with this ballpark figure of about $50 billion which is required. the savings for the world economy would be $9 trillion, so it is just incredible that we are pennypinching over this at the moment. and the third is to speed up technology transfer, so to enable more countries, particularly in sub—saharan africa, to make their own vaccines, and this is where things like the waving of patents is important but also the sharing of expertise and technology to enable countries like south africa and rewind and senegal potentially to make vaccines for the continent of africa. it�*s very simple but you feel that the g7 are looking at other things, to distract from what are the big elephants in the room. —— lou and dan. are the big elephants in the room. -- lou and dam— -- lou and dan. robert gates, executive _ -- lou and dan. robert gates, executive director _ -- lou and dan. robert gates, executive director of _ -- lou and dan. robert gates, executive director of the - -- lou and dan. robert gates, | executive director of the centre -- lou and dan. robert gates, - executive director of the centre for universal health at chatham house, thank you. —— rwanda.

a dedicated terminal for anyone arriving on a flight from any of the 43 nations on the government�*s red list has opened at heathrow airport. the move follows criticism that passengers returning to the uk from either red, amber or green list countries were being forced to queue together on arrival. heathrow said its priority was protecting the public and reducing the risk of new coronavirus variants. to talk about this is lisa minot, the travel editor at the sun. lisa joins us now. there has been a dispute between the government and heathrow over who should pay for all of this, which is why this is just should pay for all of this, which is why this isjust happening now, but do you think this is going to effectively separate separate out most people coming from the red list countries from other passengers? i think it is a good start, definitely. but also you have to remind yourself that people aren�*t always coming on direct flights, you are still going to have people coming on indirect flights, flying in via another country that might be on our amber list, and they have still come from a red list country but they will be coming into the

terminal is designated ok for embellished travellers. so although it is a good start, it is not going to take every single person who will be having to quarantine in a hotel on arrival out of those cues. all we can hope is that they manage to keep the social distancing in place and border force has enough staff in place to process people quickly. {lin place to process people quickly. on a practical level do you think it is possible to separate passengers out any further than this? i possible to separate passengers out any further than this?— any further than this? i think it would be very _ any further than this? i think it would be very difficult - any further than this? i think it would be very difficult because any further than this? i think it - would be very difficult because with the number of people who are going to be going via indirect flights, this is the best they can do in terms of, they know these flights are from areas of concern, so it makes sense to at least with those to have them going into a dedicated terminal so those people can be directly taken straight to hotel quarantine. i5 directly taken straight to hotel quarantine-— directly taken straight to hotel quarantine. is it going to mean really long _ quarantine. is it going to mean really long queues, _ quarantine. is it going to mean really long queues, i— quarantine. is it going to mean really long queues, i wonder? | quarantine. is it going to mean . really long queues, i wonder? the pcs union says this has been poorly planned, it says it is going to rely on volunteers to do overtime to

avoid huge queues. so, what are you hearing about staffing, border force staffing at the airport? weill. hearing about staffing, border force staffing at the airport?— staffing at the airport? well, we've been hearing _ staffing at the airport? well, we've been hearing that _ staffing at the airport? well, we've been hearing that really _ staffing at the airport? well, we've been hearing that really it - staffing at the airport? well, we've been hearing that really it is - staffing at the airport? well, we've been hearing that really it is not. been hearing that really it is not until august that we are going to see the levels of people on those border force desks that are actually required to have any large number of people travelling over the next months, few and it is going to be a concern. but we haven�*t seen any large queues in this first slice of countries, green list countries. that did significantly increase the number of flights coming into the uk and so far we haven�*t seen really bad delays. it remains to be seen if any of the more countries which we are going to put onto our green list, the likes of spain or greece, once they go onto the list, we are going to have a far greater number of people travelling for leisure purposes and then there could be an issue with the number of border for staff that we have available. thank ou ve staff that we have available. thank you very much _ staff that we have available. thank you very much for _ staff that we have available. thank you very much for that. _

in the uk, a clean air zone has been introduced in birmingham. drivers of older, more polluting vehicles, could be liable to pay an eight pound charge to enter the city from today, although the council has now said it will not take payments for two weeks while motorists get used to the system. our correspondent phil mackie has been following this. phil, hello to you, a change of plan, rather last—minute, explain what�*s going on? plan, rather last-minute, explain what's going on?— what's going on? yes, incredibly last-minute- _ what's going on? yes, incredibly last-minute. the _ what's going on? yes, incredibly last-minute. the launch - what's going on? yes, incredibly| last-minute. the launch officially last—minute. the launch officially took place at seven o�*clock in birmingham outside the library this morning. they pumped out some smoke from the roof of the library to symbolise the pollution that they were hoping to end. two hours later, after we heard that there had been some problems with people going to the government website to pay the fee and being redirected to bath�*s clean air zone, we learned that birmingham was pausing payments for two weeks. that means those people who have those older, more polluting vehicles that don�*t meet emissions targets, will not have to pay an e8

daily fee for driving the car, £50 for a coach or a lorry, for at least another fortnight. for a coach or a lorry, for at least anotherfortnight. it is for a coach or a lorry, for at least another fortnight. it is a little unclear as to why there was such a last—minute change of heart but there are two suggestions that i have managed to get from birmingham city council as to why it might have happened. the first is that with the payment scheme, the onus is very much on the driver, you don�*t drive into their zone and get an alert to tell you you have to pay a fee, it is on you to know that it is there and then to go online and pay it, and then to go online and pay it, and so they felt a bit more time was needed for people to get used to the idea. and secondly, there are exemptions for people who earn less than £30,000 a year and businesses based inside the zone and they had a huge amount of applications for exemptions that came in at the very last minute, last week and over the weekend, which they will need time to process. and they say that there are lots of people, other people, who they think would qualify for an exemption who they would like to

hear from over the next couple of weeks. so it has been paused for two weeks, it was the big launch this morning, we�*ve been trailing it for weeks, massive signs across the city centre, everywhere that you would enter that charging zone, but i guess it is probably a bit embarrassing for birmingham, they will deny that and tell you that it was all planned all along, and i�*m sure that is true but it does look a little bit awkward considering they had this big launch at seven o�*clock, and by nine o�*clock, things had gone completely on the other direction. , ., ., ., direction. things not quite going to ian direction. things not quite going to plan there. — direction. things not quite going to plan there, phil, _ direction. things not quite going to plan there, phil, thank— direction. things not quite going to plan there, phil, thank you - direction. things not quite going to plan there, phil, thank you very - plan there, phil, thank you very much. the first international athletes have arrived injapan for the tokyo olympics, which open onjuly the 23rd after being postponed last year. the australian softball team landed at narita airport. they were immediately ushered off for coronavirus testing.

their arrival marks a major milestone for the pandemic—postponed games which continue to face controversy. here�*s our tokyo correspondent rupert wingfield—hayes�* reaction. i have to say it is still, i think, uncertain, and certainly the feeling here is one of uncertainty. obviously, a team arriving is a big moment, especially when it�*s the first team arriving. all of the indications are, certainly from the ioc and the tokyo organising committee, that they are now determined to push ahead. we spoke to the organising committee again earlier this week and they repeated over and over that the games are going ahead and they will be safe and secure. this has become the mantra now of the tokyo olympics. safe and secure, we hear from everybody. so it certainly does seem like it is going ahead. i have to say, the australian softball team are a little bit of an anomaly because they come here more than 50 days before the olympics. they have come to actually take part in some matches with japanese teams including the national team ofjapan so that they can get themselves in practice

because back in australia, they basically didn�*t have any opportunities to play real matches. and so that is why they had decided to come here so early. we don�*t expect to see most of the teams turning up here for some weeks yet, indeed, some teams have cancelled their training camps, more than 100 training camps have been cancelled and those teams will be coming to the olympics literally days before they are due to open, so still some time to go until we will see large numbers of teams arriving here injapan. japanese tennis star and world number two noami osaka has withdrawn from the french open. the player has been in the spotlight for days after her decision to boycott post—match media duties at the grand slam tournament. she has released a statement on twitter saying... "i think now the best thing for the tournament, other players and my wellbeing is that i withdraw so that everyone can get back to focussing on the tennis." courtney bembridge has the latest.

after five days of back and forth, naomi osaka has withdrawn from the french open. it started when the 23—year—old announced she wouldn�*t take part in press conferences at roland garros due to their effects on her mental health. she said expecting players to answer questions after a defeat amounted to kicking a person while they�*re down. the organisers responded, writing in a statement, a core element of the grand slam regulations is the responsibility of the players to engage with the media, whatever the result of their match. a responsibility which players take for the benefit of the sport, the fans and for themselves. naomi osaka hit back on twitter, writing... she was fined £15,000 for not doing the post—match media after this win in her opening match, and then came the news that she had decided to withdraw completely. in a long statement posted to twitter, she said she never wanted to be a

distraction... in 2018, she beat serena williams in a controversial final, and on monday, serena williams was asked about naomi osaka�*s decision. i williams was asked about naomi osaka's decision.— williams was asked about naomi osaka's decision. i feel for naomi, i feel like osaka's decision. i feel for naomi, i feel like i — osaka's decision. i feel for naomi, i feel like i wish _ osaka's decision. i feel for naomi, i feel like i wish i _ osaka's decision. i feel for naomi, i feel like i wish i could _ osaka's decision. i feel for naomi, i feel like i wish i could give - osaka's decision. i feel for naomi, i feel like i wish i could give her i ifeel like i wish i could give her a hug because i know what it�*s like. i�*ve been in those positions. everyone is different and everyone handles things differently. so, you just have to let her handle it the way she wants to and the best way that she thinks she can.— that she thinks she can. british former number— that she thinks she can. british former number one _ that she thinks she can. british former number one and - that she thinks she can. british - former number one and commentator annabel croft says the tennis world is reeling but will have to find a path forward together. it is is reeling but will have to find a path forward together.- path forward together. it is a difficult balance _ path forward together. it is a difficult balance for- path forward together. it is a difficult balance for the - path forward together. it is a | difficult balance for the grand slams, — difficult balance for the grand slams, because we can't treat her differently — slams, because we can't treat her differently. no sportsperson can be bigger— differently. no sportsperson can be bigger than the sport and they need to make _ bigger than the sport and they need to make those commitments to the media, _ to make those commitments to the media, so_ to make those commitments to the media, so that these events can take place _ media, so that these events can take lace. , , ., . place. this is how the french federation _ place. this is how the french federation of _ place. this is how the french federation of tennis - place. this is how the french federation of tennis has - place. this is how the french - federation of tennis has responded. we are sorry and sad for naomi

osaka. the outcome of naomi withdrawing from roland garros is unfortunate. we wish her the best and the quickest possible recovery. we remain very committed to all athletes�* well—being and to continually improving every aspect of players�* experience in our tournament. of players' experience in our tournament.— of players' experience in our tournament. .,., , , tournament. naomi osaka has surgery is auoin to tournament. naomi osaka has surgery is going to take _ tournament. naomi osaka has surgery is going to take some _ tournament. naomi osaka has surgery is going to take some time _ tournament. naomi osaka has surgery is going to take some time away - tournament. naomi osaka has surgery is going to take some time away from | is going to take some time away from the court, casting doubt over whether she will be at wimbledon later this month. courtney bembridge, bbc news. the london design biennale opens today at somerset house in london and it is one of the first large scale public events to be held in the city since the start of the pandemic. one of the big attractions to the festival will be the forest for change global goals pavillion, which will see 400 trees installed into the courtyard, with the aim of raising awareness of the united nations global goals for sustainable development. the forest has been designed by leading international artist and designer es devlin and has been created in partnership

with project everyone, a not—for—profit agency co—founded by the writer and director richard curtis. hejoins me now. lovely to have you with us on bbc news today, richard. in my imagination, i have you telling us all about this while wandering through the trees, but technicalities mean you have to used a there with the trees behind you. it does look really lovely, so, explain a bit more, yf forrest, what is the symbolism here?— is the symbolism here? there's so much symbolism, _ is the symbolism here? there's so much symbolism, i _ is the symbolism here? there's so much symbolism, i can't _ is the symbolism here? there's so much symbolism, i can't tell- is the symbolism here? there's so much symbolism, i can't tell you. | much symbolism, i can�*t tell you. one of the things is that actually it was in the original rules of this amazing building never to have a tree planted, at a time when man thought we could conquer nature and exploit it. and in fact, so, this is an explosion of disobedience, that we have planted an entire forest here, to show that if we don�*t take care of nature, nature won�*t take care of nature, nature won�*t take care of nature, nature won�*t take care of us. then, also, it is kind of a forest of doubt, like all of us

i wondering what we can do in our life to make things better, and you move through the forest and come to these amazing pillars, which represent each of the sustainable development goals, because they are the to—do list for the planet. so, it�*s a complicated but beautiful symbol of how all of us can actually get stuff done to fight climate change and all the other problem is that we have in the world. is change and all the other problem is that we have in the world.— that we have in the world. is that the idea, to _ that we have in the world. is that the idea, to get _ that we have in the world. is that the idea, to get everyone - that we have in the world. is that the idea, to get everyone of- that we have in the world. is that the idea, to get everyone of us, | the idea, to get everyone of us, everyone who comes along and sees this, to think, i need to take ownership on an individual level of these global goals, not to get overwhelmed by the scale? it tells ou the overwhelmed by the scale? it tells you the government _ overwhelmed by the scale? it tells you the government is _ overwhelmed by the scale? it tells you the government is committed | overwhelmed by the scale? it tells i you the government is committed to things you want them to do. every person who works for a company can bend that companies behaviour, everyone who runs a company and make sure the company is behaving properly, all of us have the right to say to our politicians, you said you would do something urgent about

climate change last year, we are trying to inspire people with the sense that there is a to—do list, there are solutions and that they can take responsibility for them. tell us about project everyone and its involvement in this. it tell us about project everyone and its involvement in this.— its involvement in this. it was set u - , the its involvement in this. it was set up. the original— its involvement in this. it was set up, the original sustainable - up, the original sustainable development goals, quite a chunky document, and we helped design the grid that really simplified and let people know, made something that even children could understand. what we have been trying to do is make the as famous as we can, because you cannot fight for your rights if you do not know what they are, it is another effort so that everyone in the world will see, ok, how do i solve the problem? wait a minute, the solutions and all the beautiful trees, what happens to them once the comes to an end? we happens to them once the comes to an end? ~ . ~ happens to them once the comes to an end? ., ~ , ., _ happens to them once the comes to an end? . ., ~' , ., ,, end? we are thinking seriously about sustainability — end? we are thinking seriously about

sustainability so _ end? we are thinking seriously about sustainability so they _ end? we are thinking seriously about sustainability so they are _ end? we are thinking seriously about sustainability so they are going - sustainability so they are going into certain london boroughs where there are going to be planted in dark corners to bring nature to the people they are and we are giving some to a children�*s hospice as well. all the trees will be redistributed after this month of this beautiful exhibition. bud redistributed after this month of this beautiful exhibition. and what has been happening _ this beautiful exhibition. and what has been happening around - this beautiful exhibition. and what has been happening around the i this beautiful exhibition. and what. has been happening around the world for the last year, the last year and a half, your involvement in this project, is that inspiring new in terms of your creative work, writing and directing?— and directing? mainly in this direction. — and directing? mainly in this direction, it _ and directing? mainly in this direction, it makes - and directing? mainly in this direction, it makes me - and directing? mainly in this direction, it makes me think and directing? mainly in this - direction, it makes me think that the love life of hugh grant is increasingly unimportant. we have to solve the world�*s problems. there is a quote that says thousands have lived without love, not one without water. it has recalibrated my interest into trying to do things and do things urgently and i think so many people are feeling that. there is a consumer revolution going

on, people die, food and the way we travel, and we all realise it is up to all of us, we cannot leave it to the politicians.— the politicians. lovely to talk to ou and the politicians. lovely to talk to you and great — the politicians. lovely to talk to you and great to _ the politicians. lovely to talk to you and great to see _ the politicians. lovely to talk to you and great to see the - the politicians. lovely to talk to i you and great to see the exhibition will be a wonderful success. thank you very much. the headlines on bbc news... just five months old and making history — a baby with a devastating genetic disorder has become one of the first patients to get a potentially life—saving gene therapy in the uk. the heads of global bodies including the world health organisation, urge the g7 to give extra vaccines to third world countries, to halt the spread of variants. peru announces the real number of coronavirus deaths is more than double the figure previously reported ——180,000 people are said to have died. in england, as thousands rush for a jab in west london, there are further warnings that a rise in case numbers could delay the lifting of all restrictions later this month.

i think at the moment the data does suggest that we need to be cautious. we must not lose all the gains that we have made in the last few months by premature and hasty non—evidence based loosening of restrictions. london�*s heathrow airport opens a terminal for passengers arriving from the uk�*s "red list" countries. the system is design to keep travellers from high risk coronavirus destinations from mixing with other arrivals. a two week delay to birmingham�*s �*clean air zone�*. high polluting vehicles will be charged to drive into the centre of the english city, but payments won�*t start today as originally planned. let�*s get more now on a story we briefly touched on earlier — world leaders have been told coronavirus vaccines must be shared with poorer nations to prevent richer countries from being hit by imported variants of the virus. in an open letter, the heads of four major global bodies warned

of a �*dangerous gap�* in the availability ofjabs, with low—income nations receiving less than 1% of vaccines administered so far. they said countries could see fresh lockdowns if people in developing nations are not vaccinated at a faster rate. our global affairs correspondent naomi grimley is with me. good morning. the wealthier nations have been asked for quite some time now to donate extra vaccinations to developing nations and there is the covax programme and various leaders have said they will do it. but now it sounds as if they are not going fast enough and they are being told, if you will not do it for other countries, do it in your own self interest. , ., ., ., interest. there is a lot of frustration _ interest. there is a lot of frustration if _ interest. there is a lot of frustration if read - interest. there is a lot of i frustration if read between the lines of theirs that has gone into newspapers around the world that developed countries have talked the talk twin sharing doses but have not

come up with specific and —— and no amount is that they will donate. the has said that it will donate the majority of its surplus through the world which is through covax the programme to get vaccines out to developing countries but they have not put numbers or a timetable on it. we have some vague pledges, the usa at 80 million doses by the end of the year, and the european union has said 100 million by the end of this year, but still very few specifics about the end of this year it sounds like a long time when other nations are rushing to get their population is vaccinated within a matter of weeks. there is a crisis at the moment an apricot because what happened was those countries were being supplied by the india institute but they had to divert those doses domestically to divert those doses domestically to help deal with the surge they

are, so we actually are now seeing many countries cannot give their second dose to health care workers in africa and the who says they need 20 million in the next few weeks to fill that what is it going to take close this dangerous gap to quote the freeze between the promises made by the wealthier countries and the need in the developing countries? the g7 leaders are meeting soon. what can they actively do to try and speed this up? idale they actively do to try and speed this u? ~ , they actively do to try and speed this u-? . , ., they actively do to try and speed thisu? , ., , ,, this up? we will see more pressure on countries _ this up? we will see more pressure on countries like _ this up? we will see more pressure on countries like canada, _ this up? we will see more pressure on countries like canada, japan, i this up? we will see more pressure| on countries like canada, japan, the uk to come up with specific timetables and numbers of doses they are going to contribute but also the institutions like the world health organization, the world bank want $50 billion in funding upfront for countries. this is to do things like make sure their infrastructure, their health infrastructure is there because obviously the kind of crowds

we saw at twickenham yesterday with younger people being vaccinated, you cannot replicate that if you do not have a strong central health care system to administer the doses, so there is a lot of training that needs to take place on the ground to make that happen in developing countries. police in england are hunting for a 29—year—old man in connection with the deaths of a woman and child.members of the public have been warned not to approach daniel boulton, whom detectives want to trace following the deaths in the lincolnshire market town of louth. officers were called to an address on the town�*s high holme road at around half past eight last night — a woman and a child were found dead at the property. police are searching for up to seven people after a 14—year—old boy was stabbed to death in birmingham. officers say the teenager was attacked in college road, in the kingstanding area of the city, at about seven—thirty last night. indigenous groups in canada have demanded a nationwide search for mass graves after the discovery

of the remains of 215 children. the remains were found at a former residential school set up to assimilate indigenous people. the discovery has sparked outrage, prompting some in canada to lay out tiny shoes at makeshift memorials. a member of the first nations, lua mondor, said the discovery wasn�*t surprising: certainly no surprise at all. everybody in the first nations community knew that there were mass graves. we have been calling it for years. we have been telling the government for years that there are mass graves in every single residential school, but they didn�*t listen to us. canadian prime minister, justin trudeau, has pledged help but without giving details. at a news conference, he said he was horrified by what had happened. as a dad, i can�*t imagine what it would feel like to have my kids taken away from me. and as prime minister, i am appalled by this shameful policy that stole indigenous children from their communities.

a charity supporting disadvantaged young people into the arts has completed a project which saw 30 families record their experiences of lockdown. hvh arts was founded by debbi clark and the late actress helen mccrory, who at the age of 52 died from cancer earlier this year. as well as setting up a special award in her memory, the charity hopes projects such as the filming of the isolation documentaries will continue the work she was heavily involved in and continue to grow the charity to be able to support even more of the young people. with me is debbi clark, ceo and founder, hvh arts and to actor sadie frost, who is an ambassador to the charity and mentored the young people in the lockdown film project. both of you, thank you very much for joining us, i will begin by asking you what it was like to mentor the young people in this project. had

young people in this project. had you done this before? i�*ee young people in this pro'ect. had you done this before?_ you done this before? i've been involved with _ you done this before? i've been involved with a _ you done this before? i've been involved with a lot _ you done this before? i've been involved with a lot of _ you done this before? i've been involved with a lot of charities l you done this before? i've been i involved with a lot of charities and i have been involved with this charity for a while, and i love mentoring young people. when you have experienced people giving you things as a child, you want to give it back. i had those opportunities. i am from this area, chalk farm, queens crescent, camden, it was an amazing experience, they inspired me so much, they are wonderful young people. it feeds the soul to be with them and teaching them, tell us more about the documentaries, the perspectives that you were trying to get across with these films. the you were trying to get across with these films-— you were trying to get across with these films. the documentary was filmed during _ these films. the documentary was filmed during the _ these films. the documentary was filmed during the end _ these films. the documentary was filmed during the end of _ these films. the documentary was filmed during the end of the i these films. the documentary was filmed during the end of the first | filmed during the end of the first lockdown, second lockdown. we were sponsored _ lockdown, second lockdown. we were sponsored. we sent out cameras and

resources _ sponsored. we sent out cameras and resources and it was funded by local cornrnunity— resources and it was funded by local community charities as well. we supported — community charities as well. we supported over 30 young people and their families and supported over 30 young people and theirfamilies and our supported over 30 young people and their families and our aim was to -ive their families and our aim was to give them— their families and our aim was to give them mentoring, they fell in with us— give them mentoring, they fell in with us a — give them mentoring, they fell in with us a lot, we support them photography and film. sadie has been with us— photography and film. sadie has been with us a _ photography and film. sadie has been with us a long time and she supported us on zoom. the purpose was to— supported us on zoom. the purpose was to make — supported us on zoom. the purpose was to make an historical moment in their lives— was to make an historical moment in their lives and give them creativity that supported their families as welt _ that supported their families as welt it— that supported their families as well. it bonded families as well as collaborating with each other. many of the _ collaborating with each other. many of the families connected during and after and _ of the families connected during and after and family friendships. it was after and family friendships. it was a hugely— after and family friendships. it was a hugely important piece of work and i am a hugely important piece of work and lam really— a hugely important piece of work and i am really proud of what we did and the children— i am really proud of what we did and the children are being supported by this project. it and more poignant because this is carrying on the work that your friend, your co—founder the late

helen mccrory started with you, something that she was passionate about, getting young people involved in the arts and giving them that opportunity. it in the arts and giving them that opportunity-— in the arts and giving them that ouortuni . , ., opportunity. it was hugely important to me. she opportunity. it was hugely important to me- she was _ opportunity. it was hugely important to me. she was a _ opportunity. it was hugely important to me. she was a dear _ opportunity. it was hugely important to me. she was a dear friend - opportunity. it was hugely important to me. she was a dear friend of- to me. she was a dear friend of mine _ to me. she was a dear friend of mine she _ to me. she was a dear friend of mine. she was extremely passionate about— mine. she was extremely passionate about the _ mine. she was extremely passionate about the work we do here. as well as supporting us, she obviously helped — as supporting us, she obviously helped us— as supporting us, she obviously helped us with fundraising and supporting the children. this is in memory— supporting the children. this is in memory of— supporting the children. this is in memory of helen mccrory and we set ”p memory of helen mccrory and we set up the _ memory of helen mccrory and we set up the helen mccrory award as well to bring _ up the helen mccrory award as well to bring more projects like this together— to bring more projects like this together as we are a grassroots charity— together as we are a grassroots charity and it is important to support— charity and it is important to support all disadvantaged children in the _ support all disadvantaged children in the estates of queens crescent which _ in the estates of queens crescent which is _ in the estates of queens crescent which is a — in the estates of queens crescent which is a huge area of young people living _ which is a huge area of young people living in_ which is a huge area of young people living in confined spaces. it is really— living in confined spaces. it is really important that they have creativity and the work that we have done, _ creativity and the work that we have done, sadie — creativity and the work that we have done, sadie is a huge help to us and we are _

done, sadie is a huge help to us and we are very— done, sadie is a huge help to us and we are very grateful for the support she has— we are very grateful for the support she has been giving us especially over the — she has been giving us especially over the last few months. losing helen— over the last few months. losing helen was— over the last few months. losing helen was a tragedy. the helen mccrory— helen was a tragedy. the helen mccrory award is important to carry on her— mccrory award is important to carry on her legacy and support the young people _ on her legacy and support the young people going forward because they really— people going forward because they really need the work that we do. what _ really need the work that we do. what impressed you most about the films these young people made? thea;r films these young people made? they are unbelievable. _ films these young people made? iie: are unbelievable. we films these young people made? tie: are unbelievable. we had films these young people made? tiez1: are unbelievable. we had a screening, we all sat round in the space that we have, we had some snacks and drinks and ijust love the humour as well. the way they were so articulate and expressive and talking to camera, it was an insight into their resilience, they are amazing, how the edited act. it gives them a way to... a vision and an expression. for me, just seeing this work being done i saw how important it was for them and how

brilliant their heart and want to be more and more involved. let�*s do another programme. let�*s do a weekend where i want to do some acting with them. it is amazing. i have never seen anything so hands—on or anything like it. and the children are brilliant and funny. they are like from seven up until 16. and they are all characters. i love them all. it 16. and they are all characters. i love them all.— 16. and they are all characters. i love them all. it sounds incredible. how do you — love them all. it sounds incredible. how do you ensure, _ love them all. it sounds incredible. how do you ensure, you _ love them all. it sounds incredible. how do you ensure, you talk- love them all. it sounds incredible. how do you ensure, you talk so i how do you ensure, you talk so enthusiastically, it was lovely to see the smiles on your face is, what impressed you about the films, loads of things you are thinking about, how do you keep on making sure that those opportunities are there because obviously you have got the arts charity but you could reach out to many more children if had the resources. i would love a thought from both of you on that. it is resources. i would love a thought from both of you on that.- from both of you on that. it is a aood

from both of you on that. it is a good model. — from both of you on that. it is a good model, it _ from both of you on that. it is a good model, it can _ from both of you on that. it is a good model, it can be - from both of you on that. it is a good model, it can be run i from both of you on that. it is a good model, it can be run quite easily and we bring an a lot of other people from the community. my friend who is a graffiti artist at a weekend. my daughter who is studying fashion did some stuff as well. with fashion did some stuff as well. with fashion and sewing and knitting. there are so many people in the local community that can give back to the young people. it works as a model. debbie works 24 hours a day on it but it is important for everyone around to put back in. there are many people who can help. everybody can... some people might think there isn�*t much they could to teach young people certain aspects of creativity but there are so many things that can be done. and they love it. they love being involved. we are almost out of time, your

thoughts on that, the creativity out of the extraordinary circumstances of the extraordinary circumstances of the extraordinary circumstances of the pandemic. igrate of the extraordinary circumstances of the pandemic.— of the extraordinary circumstances of the pandemic. we would love you to look at our— of the pandemic. we would love you to look at our website, _ of the pandemic. we would love you to look at our website, we _ of the pandemic. we would love you to look at our website, we have i to look at our website, we have damian— to look at our website, we have damian lewis supporting us, taking over helen's uat. it is important to keep— over helen's uat. it is important to keep up— over helen's uat. it is important to keep up theirwork over helen's uat. it is important to keep up their work with the young children — keep up their work with the young children. we have got resources that need supporting all the time. any help. _ need supporting all the time. any help. take — need supporting all the time. any help, take a look at the work we do. we support— help, take a look at the work we do. we support 300 young people in that square _ we support 300 young people in that square area of queens crescent which is much _ square area of queens crescent which is much needed for disadvantaged children — is much needed for disadvantaged children. it is really, really important and i thank you all at the bbc for— important and i thank you all at the bbc for listening to us because the work that— bbc for listening to us because the work that we do so important. it is ureat work that we do so important. it is treat to work that we do so important. it is great to hear— work that we do so important. it 3 great to hear about the project. you very much. the delayed sequel to the thriller a quiet place has become the biggest hit at north american box offices since the start of

the covid—19 pandemic. a quiet place part ii made an estimated 34 million pounds between friday and sunday. one of its stars, london—born actor noahjupe, has been speaking to louise minchin. she began by asking him about his famous mum. lots of people know your mum, as well, because she wasjulie in coronation street. yeah, i mean, i�*m so lucky to have my mum, you know, so to have her, you know, when i was growing up, going on sets at nine and stuff, to have her there supporting me was always very special. yeah, so nine�*s pretty young. do you remember that — that was your first, what, tv orfilm role, was it? which one was it? it was a tv film role, actually — it was a song forjenny, about the 7/7 bombings. is jenny dead? i remember when it finished, i... i cried all the way home in the car. 0h! because you were going to miss them? yeah, i loved it. it was like a second home to me because everyone was so... it was such a community on set that

when i got in the car and i realised that i wasn�*t going to get to go back to that community ever again, it was really kind of heartbreaking for me. and that�*s when i kind of knew that this job would be something that i would be passionate about and, you know, something that i would love doing. there are people out there. people worth saving. and for fans of a quiet place... so we prepare ourselves for scares. you�*re alongside emily blunt again. and just give us a quick insight — you know, it starts where? it basically follows straight on from the events of the end of the last one. the safety has just gone out the window in this movie so you�*re just on number ten the whole time. oh, it�*s scary! what�*s it like being in it? the scariest thing about a quiet place is the fact... the jump scares. yeah.

like, you know, when you think everything�*s ok, and suddenly this happens, right? and for us, because we�*ve read the script, we know what�*s happening, we know that something�*s coming. so it defeats the aspect of surprise. i have to say, filming it wasn�*t scary, but then when i went to the cinema and watched the first one, i was... i was so scared, i was like... even though you know what�*s going to happen. even though i know what�*s happening! iwas... iwas, like, closing my eyes like this when i was watching it because i was so scared, so, yeah. for a quiet place, did you learn... did you learn actual sign language, as well? i mean, milli, who is also one of my best friends... millicent simmonds, who stars alongside you, yeah. millicent simmonds is, you know, i... immediately, we started emailing over the first —

before the first a quiet place. and then once i met her, i was like, i need to speak to her, i need to talk to her. and obviously, there was a interpreter there so i could, but i wanted it to be just between us. so then i started to learn the alphabet of sign language and i�*d spell out the word that i wanted to say and she�*d sign it back to me. so it would take us an hour — it would take, like, half an hourfor me to say, "how are you?" because i�*d be like, how...are you? that�*s a lovely skill to have, because you�*ll meet people in your life who you�*ll be able to talk to that you wouldn�*t, you know, wouldn�*t be able to sign to before. i was on a plane with this old woman who was deaf and we were flying back to england or something, and she needed help. and this guy couldn�*t communicate with her. he was like, you know, trying to talk to her. and i rememberjust going over and saying, like, "do you know american sign language?" she was like, "yes." and then kind of talking to her and finding out what she needed and stuff, and helping the guy that was trying to help her.

so, yeah, i mean, it�*sjust really cool to know and, you know, it�*s a different language, which is always exciting. i�*m just looking at some of the people you�*ve worked with, and it literally is the who�*s who of hollywood. so they think you killed her? no! so why else all of this, then? i don't know. sandy and caroline will probably be there, won't they? _ hey, jack, come sit here. in a sec. is it ok ifjack comes over? those men killed mum. we've decided it'd be best if your auntie margaret came and stayed with us. nicky needs a mother. we'll be strong. you can�*tjust push the car hard. just amazing. craziness. yeah. some of them, um, you know, for example, cillian, who i�*ve recently worked with — i didn�*t actually really know a lot about him.

the people that are left...what they've become. after the shoot, obviously, i was like, "right, i�*ve got to watch peaky blinders." now i�*m the biggest fan. ithink... i think i wouldn�*t have been able to speak to him, knowing some of the stuff he�*s done. you know, he�*s definitely now... i very much look up to him as an actor. i watched back today, the night manager, some of the night manager, when you star alongside lots of superstars, but not least tom hiddleston. thank you very much, sir, for rescuing me. i never actually got to see the whole thing. i�*ve just seen my episodes because obviously, until recently, i wouldn�*t have understood it and understood what was happening. he probably won�*t remember me. it would be interesting if i ever meet him again to be like, "oh, yeah, i was on a beach with you, throwing stones in the water." not only do you have this extraordinarily and hugely successful career — you, like anyone else, have to do exams. you need to get some gcses. how�*s that been? um... it�*s annoying and painful

and...| haven�*t got much sleep recently, but, you know, i�*m...in it to win it. i�*m excited. 0k. it�*s been a real — listen — a real pleasure to talk to you. thank you very much indeed, noah. thank you. it�*s been very warm here in the uk for the past few days, so let�*s take a look at how some people were cooling down yesterday — over a hundred feet above the streets of london. this sky pool is near the us embassy in nine elms — just south of the thames — and is believed to be the world�*s first transparent pool — built between two skyscrapers.

it looks really spectacular, swimmers can enjoy views of parliament and the london eye — and the london eye — while they swim their lengths of the 25 metre pool. the catch is, you have to be a resident to use it. you�*re watching bbc news. now it�*s time for a look at the weather, with nick miller. hello. highland scotland is the current holder of the uk�*s highest temperature of the year so far, after hitting 25.1 yesterday in kinlochewe. now, today, that temperature may be surpassed, and more probably in parts of england and wales, which will be a little warmer than yesterday. whilst most have the sunshine, this weather front close to northern ireland and western scotland is providing more cloud, and we have already today seen a little rain across western parts of northern ireland. that will clear away and it will brighten up, but for the western isles, we will continue with cloud and patchy rain. elsewhere, plenty of sunshine but some misty low cloud on some of the eastern coasts,

keeping it much cooler. elsewhere, temperatures will be in the rage of 20—25, may be up to 26. tonight, the low cloud and mist in eastern scotland and the northern isles becomes a bit more widespread. whilst most areas are dry and clear, we will have some thundery showers edging across the channel islands and into south—west england as the night goes on. for many of us, temperatures will be holding up in double figures. tomorrow, most areas will continue to see the sunshine but there will be more cloud across southern england into wales and the midlands later and northern ireland as we start to bring a weather system with some outbreaks of showery rain that could be thundery very gradually further north. and there will still be parts of the coast of north—east england and eastern scotland will some low cloud and mist keeping it cooler. inland, it will be another warm to very warm day, but a bit breezier.

this area of low pressure overnight and into thursday, with uncertain progress, takes the thicker cloud and chance of thundery rain further north. on thursday, whilst by no means certain exactly where that will be, whereas elsewhere, variable cloud, sunny spells, not as warm as it has been, but it will still feel warm in the sunshine. by friday it looks as if that system will have cleared away eastwards and we are left with variable cloud, sunny spells, most places with a dry day, but another weather system with thicker cloud and a chance of showery rain coming into northern ireland.

this is bbc news. the headlines at 11am. just five months old and making history — a baby with a devastating genetic disorder has become one of the first patients to get a potentially life—saving gene therapy in the uk. a high—rise apartment block in east london, where a fire broke out last month, had serious fire safety issues including a faulty smoke ventilation system, an investigation finds. the heads of global bodies including the world health organization, urge the g7 to give extra vaccines to third world countries, to halt the spread of variants. london�*s heathrow airport opens a terminal for passengers arriving from the uk�*s "red list" countries. the system is designed to keep travellers from high—risk coronavirus destinations from mixing with other arrivals.

peru announces the real number of coronavirus deaths is more than double the figure previously reported, 180,000 people are said to have died. in england, as thousands rush for a jab in west london, there are further warnings that a rise in case numbers could delay the lifting of all restrictions later this month. i think at the moment, the data suggests that we need to be cautious, we mustn�*t lose all the gains that have been made over the last few months by a mature and hasty, —— premature and hasty —— premature and non—evidence—based loosening of restrictions. a two—week delay to birmingham�*s clean air zone. high—polluting vehicles will be charged to drive into the centre of the english city, but payments won�*t start today as originally planned. and coming up this hour: naomi osaka pulls out of the french open, saying she�*s suffered from depression since winning herfirst grand slam title in 2018.

a five—month—old boy from london has become one of the first children in the uk to be treated with a ground—breaking new gene therapy. arthur morgan, who has spinal muscular atrophy, is being treated with zolgensma. at a cost of £1.79 million per patient, it is the world�*s most expensive drug. the nhs has negotiated a confidential discount for the treatment, which can increase life expectancy by as much as 40 years. the development means that potentially dozens of infants could be treated by the nhs. around 40 children are born with the most severe form of the disorder every year. and the sma uk charity says newborns in britain should be screened for sma, as happens in other countries.

the charity says early diagnosis and treatment is vitalour medical editor fergus walsh explains. this is the world�*s most expensive medicine. the list price of zolgensma is almost £1.8 million, though the nhs has negotiated a confidential discount, which will enable dozens of affected infants to be treated each year. five—month—old arthur is one of the first to benefit. he has spinal muscular atrophy — sma — a genetic condition which causes progressive muscle weakness. without treatment, those affected rarely live beyond the age of two. arthur is unable to lift his head, and struggles to move his arms and legs, but this single infusion should prevent further loss of nerve cells. it�*s been massive, massive ups and downs, but being able to now have the treatment is just

going to be a game—changerfor us and give arthur the best possible life he could have. around one in every 10,000 babies is born with spinal muscular atrophy. what is remarkable is that this one—off treatment may permanently stop any further decline in arthur�*s muscle function. so how does zolgensma work? it contains a healthy copy of a missing orfaulty gene called smn—1. this is inserted into a harmless virus. in the body, the virus delivers the replacement gene into the nucleus of motor neuron cells. this is essential to prevent those cells from gradually dying. the now healthy motor neuron cells start producing the missing smn protein, which is vital for muscle function. how�*s arthur? evelina children�*s hospital in london is one of a handful of centres in the uk which will offer this ground—breaking gene therapy.

20 years ago, a baby born with a severe form of sma would have a very shortened life expectancy. we can now offer treatment that can really alter the outlook for these children. some other infants treated with zolgensma have seen their condition notjust stabilise, but improve. arthur�*s parents say they know it�*s not a cure, and they�*re simply delighted that he�*s being treated. fergus walsh, bbc news. let�*s hear now about a little girl called toya who has had this —— torah. gene therapy treatment. tora was able to have the treatment while her family were living in new york. herfamily are now back in the uk. her dad rajdeep patgiri joins us from south west london. it's it�*s extraordinary he is getting this treatment. i know you had to go through hoops for your daughter. tell us about her and how you

managed to get the treatment. 50. managed to get the treatment. so, she was managed to get the treatment. srr, she was diagnosed managed to get the treatment. 557, she was diagnosed around the same age as arthur, she was diagnosed at five and a half months in february 2019 and at the time, there was no treatment available for her in the uk. so we tried to look to the us to get her the treatment of their and we saw zolgensma in 2019, two years ago. at the time, she could only sit with support but had no mobility and she couldn�*t do anything for herself. since then, it�*s been almost two years and she has set independently, she can stand and she is able to take steps and we are hoping that one day she will be able to walk independently. she can have a life on her own and not depending on other people or her parents throughout her life. it

on other people or her parents throughout her life.— on other people or her parents throughout her life. it must be so nice to be — throughout her life. it must be so nice to be on _ throughout her life. it must be so nice to be on the _ throughout her life. it must be so nice to be on the side _ throughout her life. it must be so nice to be on the side of - throughout her life. it must be so nice to be on the side of that i throughout her life. it must be so nice to be on the side of that you | nice to be on the side of that you are now and seeing the impact that the treatment had on your daughter. if you hadn�*t been able to get it, as you said, you moved to the states, you managed to get it through your health insurance in the states, so you must have felt extremely lucky to be able to do that. what would the prognosis have been if you hadn�*t been able to get that? been if you hadn't been able to get that? ~ ., ., , ., been if you hadn't been able to get that? . ., , .,, that? with a diagnosis two years auo, we that? with a diagnosis two years ago. we clearly _ that? with a diagnosis two years ago, we clearly remember i that? with a diagnosis two years ago, we clearly remember the l ago, we clearly remember the prognosis was that the life expectancy was three years. and we should hold a day till then. but we knew there were treatments on the right horizon. there was also another treatment and that eventually got approved in the uk after we moved to the us, so i mean, life for us and for people with this

disease is awful. we shouldn�*t look at it is a fickle diagnosis any more or a fatal diagnosis, it is a. i don�*t know how much it�*s going to improve, but they can give people a life with happy memories. tell improve, but they can give people a life with happy memories.— life with happy memories. tell me about her- — life with happy memories. tell me about her. you _ life with happy memories. tell me about her. you say _ life with happy memories. tell me about her. you say she _ life with happy memories. tell me about her. you say she was - life with happy memories. tell me about her. you say she was not i about her. you say she was not moving around and now she is developing, tellest what extent there is any sign of what she had. yes, she eats normally like normal children breathes and eats, but the only drawback is that her movements are still slow and she cannot react as fast as she is not able to take steps on her own. she was supposed to be on this call but she was throwing a tantrum, and for most parents, there will be a stressful

situation but we are happy that she is able to throw tantrums. filth. situation but we are happy that she is able to throw tantrums.- is able to throw tantrums. oh, my cosh, if is able to throw tantrums. oh, my gosh. if she _ is able to throw tantrums. oh, my gosh, if she wanders _ is able to throw tantrums. oh, my gosh, if she wanders into - is able to throw tantrums. oh, my gosh, if she wanders into the i is able to throw tantrums. oh, my| gosh, if she wanders into the room we would love to welcome her and see her. going forward, what are the expectations? we her. going forward, what are the expectations?— her. going forward, what are the exectations? ~ ., �* ~ ., ~ expectations? we don't know. medical science is evolving _ expectations? we don't know. medical science is evolving all _ expectations? we don't know. medical science is evolving all the _ expectations? we don't know. medical science is evolving all the time, - science is evolving all the time, how this treatment landscape will change over the next 5—10 years, it still to be seen. we have the luxury that now we can wait and see and not every day we are, now we look for improvement, but if some happens, that we can have a cure fully ten years down the road, then i thought were hoping for. you years down the road, then i thought were hoping for-— were hoping for. you 'ust use the word miracle h were hoping for. you 'ust use the word miracle and i were hoping for. you 'ust use the word miracle and a i were hoping for. you just use the word miracle and a store - were hoping for. you just use the word miracle and a store that i were hoping for. you just use the l word miracle and a store that came into my mind is a look at you and practically feel the energy radiating from you and your happiness at what you have

experienced. obviously, you do go to throw something traumatic to something that does not feel like a miracle. , , ., ., , ., miracle. yes, it is already a miracle- — miracle. yes, it is already a miracle- i — miracle. yes, it is already a miracle. i mean, _ miracle. yes, it is already a miracle. i mean, it's- miracle. yes, it is already a miracle. i mean, it's not i miracle. yes, it is already a miracle. i mean, it's not a l miracle. yes, it is already a i miracle. i mean, it's not a cure, miracle. i mean, it�*s not a cure, but it is the closest thing that there is to a cure. once it is lost, it will be impossible to regain but she has progressed with whatever was left with her motor neurons and we are hoping that this progress continues in the future as well. there are calls for there to be screening for sma and it happens in other countries.— other countries. what are your thou . hts other countries. what are your thoughts on — other countries. what are your thoughts on that? _ other countries. what are your thoughts on that? it's - other countries. what are your| thoughts on that? it's probably other countries. what are your i thoughts on that? it's probably the thoughts on that? it�*s probably the most uncontroversial topic on the planet. it�*s good for the children because most children who are diagnosed just after birth are treated immediately, they have a normal life, so, when i say is not a cure, is the closest thing, is

possibly most applicable to those who are treated in the first month of their life. so, there is no argument against doing that. finally, do you have a message for arthur and his family? you are part of a small community so i guess you will meet sunday but i wonder what you�*re thinking of this morning. i you're thinking of this morning. i hope i will get to meet arthur and his family and other families were waiting for this treatment are across the sma community. the only thing i can say is be patient, be persistent, it�*s a long road but it�*s a road full of hope. it�*s persistent, it's a long road but it's a road full of hope. it's great to talk to you. _ it's a road full of hope. it's great to talk to you. thank _ it's a road full of hope. it's great to talk to you. thank you - it's a road full of hope. it's great to talk to you. thank you very i it's a road full of hope. it's great i to talk to you. thank you very much indeed and say hi to herfor us. i�*m sorry we could meet her but may be another time. sorry we could meet her but may be another time-— a high—rise apartment block where a fire broke out last month had serious fire safety issues including a faulty smoke ventilation system. 35 people had to be rescued from new providence wharf in east london after an electrical

failure resulted in a fire which spread three floors. a provisional investigation by the london fire brigade has discovered a detector failed to activate an automatic ventilation system and smoke poured into a corridor. the british medical association has joined calls for the government to delay a decision on lifting all remaining lockdown restrictions, which is due to take place in england on the 21st ofjune. some government scientific advisers continue to warn that while the uk�*s vaccination programme has been successful, it does not mean the battle against coronavirus is over. they suggest that even a short delay to the government�*s current road map could have a significant impact on the spread of the virus. world leaders have been told coronavirus vaccines must be shared with poorer nations to prevent richer countries from being hit by imported variants of the virus. in an open letter, the heads of four major global bodies warned of a "dangerous gap" in the availability ofjabs, with low—income nations receiving less than 1% of vaccines

administered so far. meanwhile, the world health organization has announced a new naming system for covid—19 variants using letters of the greek alphabet. global health leaders say the move is to help simplify discussions and also to remove stigma from the names. earlier this month, the indian government criticised the naming of a variant first detected in the country as "the indian variant." the variants are of course a key concern of those advising against a total easing of restrictions later this month. here�*s the chair of the british medical association, dr chaand nagpaul. when you look at the conditions for coming out of...the road map conditions, one of those criteria was to make sure there were no concerns about new variants. so i think, at the moment, the data does suggest that we need to be cautious. we mustn�*t lose all the gains that we�*ve made in the last few months by premature and hasty, non—evidence based loosening of restrictions. one of the sectors which will be

affected by the delay to lockdown easing is the late night economy — michael kill is the ceo of the night time industries association. welcome and thank you forjoining us. we are hearing a 50—50 about whether it will happen in the 21st ofjune. what are your thoughts? hugely concerning for us. many of these businesses are now preparing to open for the 21st, they can�*t wait for the 14, it very clear that 95% of these businesses are already starting to making financial commitments to the opening on the zist, commitments to the opening on the 21st, so there is a real concern if we don�*t get clarity from government that many of these businesses will be compromised financially. they have also stated that many of them, nine out of ten night—time businesses have veered off the road map, if they have done this, it would threaten their survival and so it�*s a massive level of concern, not just for the late—night sector but

also the hospitality sector in general because they are reliant on this date of the 21st. as you can appreciate, there are a lot of people panicking out there that have committed too far and now you�*re sat with this position which could compromise them.— with this position which could compromise them. with this position which could comromise them. . ., ., ., compromise them. what about a delay of a few weeks? _ compromise them. what about a delay of a few weeks? the _ compromise them. what about a delay of a few weeks? the argument - compromise them. what about a delay of a few weeks? the argument is i compromise them. what about a delay of a few weeks? the argument is that l of a few weeks? the argument is that if all over 50s are vaccinated by the 21st ofjune, you would still need to add three weeks in four the full immunity to actually kicking and three weeks and then is better than running the risk of the new variant continuing to spread and causing problems and perhaps a further worse lockdown later. this causing problems and perhaps a further worse lockdown later. as you can understand. _ further worse lockdown later. as you can understand, the _ further worse lockdown later. as you can understand, the late-night i can understand, the late—night economy has been really the hardest hit and as you can understand, last year, when we were sat in march and said we were going to be locked down for six weeks, and then it escalates and now you�*re here today and the concern is that any delays would cause quite a bit of anxiety across

the sector and i think the government needs to be very clear that any delay or any further lockdown would compromise these businesses massively. the only other option would be to give them proportionate support to see them through, but we need to hear that i�*m soon and we need to understand exactly what the government�*s plan is. exactly what the government's plan is. ., ., ., exactly what the government's plan is. you have said that 95% of businesses — is. you have said that 95% of businesses in _ is. you have said that 95% of businesses in the _ is. you have said that 95% of businesses in the night-timej is. you have said that 95% of - businesses in the night-time economy businesses in the night—time economy have already started making financial commitments and readiness for opening on the 21st ofjune. what is the level of those commitments?— what is the level of those commitments? , ., ., commitments? well, severalthousand -ounds commitments? well, severalthousand ounds for commitments? well, severalthousand pounds for the — commitments? well, severalthousand pounds for the smallest _ commitments? well, severalthousand pounds for the smallest business i commitments? well, severalthousand pounds for the smallest business to i pounds for the smallest business to potentially, 50 or £60,000 in terms of the businesses that haven�*t been open since last year and so if you�*re a nightclub or an event space that hasn�*t been open, you�*re going to have to look at your systems, staff, looking entertainments etc but also on the other side in terms of hospitality, they are looking at expanding and so they�*re going to

have to at some point bring their staff back. there is a huge range of financial commitment from the smallest all the to the biggest and of this industry as a cumulative total have invested millions into getting to a point where they can reopen and so the concern is this last—minute delay could cause some real hard hitting economic impact on these businesses and it needs to be really looked at because itjust creates a level of anxiety and panic among people. creates a level of anxiety and panic among people-— creates a level of anxiety and panic among people. thank you for “oining us. world leaders have been told coronavirus vaccines must be shared with poorer nations to prevent richer countries from being hit by imported variants of the virus. in an open letter, the heads of four major global bodies warned of a �*dangerous gap�* in the availability ofjabs, with low—income nations receiving less than 1% of vaccines administered so far. they said countries could see fresh lockdowns if people in developing nations are not vaccinated

at a faster rate. our global affairs correspondent davis us this update.— davis us this update. there is certainly a — davis us this update. there is certainly a lot _ davis us this update. there is certainly a lot of— davis us this update. there is certainly a lot of frustration i davis us this update. there is i certainly a lot of frustration that if you read between the lines of this head that spun into newspapers around the world that developed countries have talked to the talk when a cop comes to sharing doses but they haven�*t come up with specific amounts that they will donate and that includes the uk, which has broadly said that they will donate the majority of its surplus to the developing world through covax, the global programme to get vaccines out to poorer countries and yet they haven�*t actually put numbers on it or even a timetable. we have had vague pledges, the us says it wants to get 80 million doses out to developing countries by the end of this year and also at the european union has said 100 million by the end of this year, but still very few specifics about how that will happen. and there is a real crisis in the moment

and africa because what happened was those countries were being supplied by india�*s sarum institute and in india had to divert those doses domestically to help deal with the surge there and we actually are now seeing many countries not being able to give a second doses to health care workers in africa and the who says they need 20 million in the next few weeks to fill that gap on second doses. rob yates, executive director of the centre for universal health at chatham house, says there�*s been a lot of talk, but not much action so far.... we are seeing a lot of vague promises about freeing up vaccines once we are vaccinated and good words, but it�*s not really being matched up with action and we are going to be sound sitting on the enormous sucks top as vaccines and potentially talking about booster vaccines in the uk, so i would be

having my third shot potentially in september and really this is outrageous that this is happening when front line health workers in places like peru and malaysia are not being protected. a dedicated terminal for anyone arriving on a flight from any of the 43 nations on the uk government�*s red list, has opened at heathrow airport. it follows criticism that passengers returning to britain from either red, amber or green list countries were being forced to queue in arrival halls together. our transport correspondent caroline davies reports. when international travel restarted last month, some couldn�*t wait to get away. but while this was the view in departures, in arrivals, passengers from green list, low risk countries, queued up in the same hall as arrivals from high—risk, red list countries. since mid—february, all arrivals from red list countries have had to stay in quarantine hotels for ten days to stop the spread of variants of concern. but before they go into isolation, some spent hours queued up alongside other, lower risk passengers.

despite the separate queues, some passengers felt very uncomfortable being so close for so long. from today, any arrivals coming in on direct flights from red list countries will be processed at terminal three. the terminal has been brought back to operation after being closed during the pandemic. while neither side will confirm who is paying for the reopening and running of the terminal, it is understood that the government is picking up a large part of the cost. but one of the biggest unions representing border force employees, the pcs, has said they are concerned the decision was taken out short the decision was taken at short notice, meaning that key social distancing procedures are not in place and that the terminal would be understaffed. the home office have said that border force is mobilising additional staff to help minimise queueing times for compliant passengers. whilst a government spokesperson said the new dedicated terminal at heathrow for arrivals from red list countries will enable passengers to be processed as safely and as efficiently as possible. international travel is likely

to remain very different for a while to come, and heathrow have said they expect to have a dedicated red list terminalfor some time. caroline davies, bbc news. rowland kao is professor of epidemeology at the university of edinburgh. welcome and thank you forjoining us. it�*s not a straightforward thing to do, to open a terminal specifically for passengers coming from red list countries, but how important is to do that? it�*s important is to do that? it's obviously — important is to do that? it's obviously that _ important is to do that? it�*s obviously that people coming directly from low risk country are going to have the highest chance of being infected already, high—risk countries, but they were coming from other locations is going to be critical and airports are fortunately really good —— but unfortunately good prices for it to transmit, they doors, insulation is not necessarily good and separation is welcome. we not necessarily good and separation is welcome-— not necessarily good and separation is welcome. ~ ., ., , is welcome. we have had the red list for three and —

is welcome. we have had the red list for three and a _ is welcome. we have had the red list for three and a half— is welcome. we have had the red list for three and a half months - is welcome. we have had the red list for three and a half months since i for three and a half months since quarantine hotels were introduced and it is only happening now. obviously, better late than never i guess, but is it a bit like closing the stable door after the horse has bolted this point?— bolted this point? yes, certainly s-ueakin bolted this point? yes, certainly speaking from — bolted this point? yes, certainly speaking from an _ bolted this point? yes, certainly. speaking from an epidemiological point of view, the risks have been known and they have been known for a long time. i am certainly not party to decisions as to why these things haven�*t been done before, but it�*s always been an issue and it�*s something that we have been aware of. is something that we have been aware of. , . ., ., something that we have been aware of. ., of. is it clear how many people cominu of. is it clear how many people coming into — of. is it clear how many people coming into this _ of. is it clear how many people coming into this country - of. is it clear how many people coming into this country from i of. is it clear how many people i coming into this country from red list countries are actually testing positive? list countries are actually testing ositive? ., ., , ., �* positive? unfortunately, i don't have that data _ positive? unfortunately, i don't have that data directly, - positive? unfortunately, i don't have that data directly, we i positive? unfortunately, i don't have that data directly, we do l positive? unfortunately, i don't i have that data directly, we do know certainly that in the period where the cases were particularly low, at the cases were particularly low, at the end of the lockdown period, the vast majority of cases of infection was coming from overseas and so travel is critically important. the exportation of the red list

countries would be a major risk of infection but on the other hand, keepin infection but on the other hand, keep in mind that the number coming from red list countries is relatively low.— from red list countries is relatively low. we are in a situation _ relatively low. we are in a situation where _ relatively low. we are in a situation where the indian relatively low. we are in a - situation where the indian variant, now called the delta variant, is accounting for 75% of new cases. presumably, it came into this country from a traveller coming from abroad. how has it got to this point? we have track and trace, we have been in lockdown, we have the restrictions on the borders. yes. have been in lockdown, we have the restrictions on the borders.- restrictions on the borders. yes, so the first thing _ restrictions on the borders. yes, so the first thing to _ restrictions on the borders. yes, so the first thing to keep _ restrictions on the borders. yes, so the first thing to keep in _ restrictions on the borders. yes, so the first thing to keep in mind i restrictions on the borders. yes, so the first thing to keep in mind is i the first thing to keep in mind is that it isn�*t —— is more than one person and one person can start things off, but certainly, as the point of introduction of the delta variant, there were lots of people coming from overseas and in particular, before people from the

primary areas of concern had the red list restrictions put on them. going backin list restrictions put on them. going back in a more general point, every single system has a leakage in every single system has a leakage in every single stage. the tests are not perfect. test and trace is not perfect, quarantine and none of the things are perfect and as you increase the volume of people coming through, the chances of some leakage will increase and so, really, the primary thing to do if you want to keeping things done is to keep the number of people travelling down to the minimum that we can afford to do. ~ . the minimum that we can afford to do. . ., ., , ., the minimum that we can afford to do. ~ ., ., i. ., , ., do. what are your thoughts then on lockdown easing _ do. what are your thoughts then on lockdown easing on _ do. what are your thoughts then on lockdown easing on the _ do. what are your thoughts then on lockdown easing on the 21st - do. what are your thoughts then on lockdown easing on the 21st of i do. what are your thoughts then on | lockdown easing on the 21st ofjune? well, it would certainly seem to have risks associated with it. we are at this criticaljuncture where the number of the vaccinated are high and so it�*s been a fantastic success story, but the number of people with single jabs are still quite high and unfortunately they tend to be clustered in certain groups and certain ethnic groups,

areas of deprivation still have an issue where they may have higher numbers and there�*s all sorts of reasons why that may be. it would be from an epidemiological point of view that official if we could delay longer, while keeping in mind that there are all sons of other things going on where there pushing in both terms of economics and other things for getting those restrictions to be eased. . ~ for getting those restrictions to be eased. ., ~' , ., , for getting those restrictions to be eased. ., ~' ,, , . police in england are hunting for a 29—year—old man in connection with the deaths of a woman and child. members of the public have been warned not to approach daniel boulton, whom detectives want to trace following the deaths in the lincolnshire market town of louth. officers were called to an address on the town�*s high holme road at around half past eight last night — a woman and a child were found dead at the property. police are searching for up to seven people after a 14—year—old boy was stabbed to death in birmingham. officers say the teenager was attacked in college road,

in the kingstanding area of the city, at about seven—thirty last night. more now on the news we brought you earlier — an investigation has found that a high rise apartment block, where a fire broke out last month, had serious fire safety issues including a faulty smoke ventilation system. 35 people had to be rescued from new providence wharf in east london after an electrical failure resulted in a fire which spread three floors. let�*s speak to our correspondent sean dilley. tell us more. we have to understand what happened _ tell us more. we have to understand what happened with _ tell us more. we have to understand what happened with the _ tell us more. we have to understand what happened with the fire - tell us more. we have to understand what happened with the fire itself i what happened with the fire itself in there was a fault in the fuse box on the eighth floor flat and what happened is that when the fire broke out, the fire itself had escaped a window that was opened and a balcony and smoke had bellowed out the door to the flat but had been left open. if the sensors had been working, that would have track triggered the ventilation system and that seems that was not the case, but what

happened is that when that smoke filled the hallway, it filled the only escape route. there were concerns at the time and you may remember this in terms of the cladding that was on the outside of the building, the preliminary investigation said that was not a significant cause to the external fire, but they do say that this should serve as a warning to any high rise building owner. there still needs to be a culture change, it�*s too late to see what the work after a fire has happened in of the london fire brigade are assigned a culture that still needs to happen. thank you very much. hello. anotherfine, very warm day in the sunshine for many of us today. there is a weather front close to the west of northern ireland. it has produced a bit of rain so far today, but that clearing, brightening up in northern ireland, especially in the east. patchy rain into the western isles. especially in the east. elsewhere, though, it�*s dry but some low cloud and mist keeping parts of the coast of north—east england, eastern scotland and it will be elsewhere, of course, in the sunshine, with temperatures

up to 25, 20 six celsius in the warmest spots today. further low cloud and mist in the northern isles, eastern scotland overnight. have a look at this. some showers, perhaps thundery rain into the channel islands and south—west england later in the night, and a night which for many of us has temperatures into double figures. now, tomorrow, this area of cloud with showers, perhaps thundery rain gradually extends across more of southern england into wales, parts of the midlands and northern ireland as the day goes on. some low cloud and mist, parts of the coast of north—east england, eastern scotland keeping it cooler than it will be elsewhere where you get to see some of that very warm sunshine.

hello, this is bbc news with joanna gosling. the headlines: just five—months old—and making history — a baby with a devastating genetic disorder has become one of the first nhs patients to get a potentially life—saving gene therapy. a high—rise apartment block in east london where a fire broke out last month had serious fire safety issues including a faulty smoke ventilation system, an investigation finds. the heads of global bodies, including the world health organisation, urge the g7 to give extra vaccines to third world countries to halt the spread of variants. heathrow airport opens a terminal for passengers arriving from �*red list�* countries. the system is design to keep travellers from high—risk coronavirus destinations from mixing

with other arrivals. peru announces the real number of coronavirus deaths is more than double the figure previously reported —180,000 people are said to have died. in england, as thousands rush for a jab in west london, there are further warnings that a rise in case numbers could delay the lifting of all restrictions later this month. i think at the moment, the data suggests that we need to be cautious, we mustn�*t lose all the gains that have been made over the last few months by a mature and hasty, non—evidence—based loosening of restrictions. a two week delay to birmingham�*s �*clean air zone�* — high—polluting vehicles will be charged to drive into the city centre, but payments won�*t start today, as originally planned. sport now and, for a full round—up from the bbc sport centre, here�*s austin halewood. hi,joanna. good morning.

we�*ll look ahead to gareth southgate�*s england squad announcement in a moment, but first organisers of the french open say they feel "sorry and sad" that naomi osaka felt she had to withdraw from the tournament to protect her mental health. the world number two had been fined for refusing to speak to the media after her matches. she said she wanted to protect herself after suffering "long bouts of depression" since winning herfirst grand slam title in 2018. joe lynskey reports. naomi osaka called it a situation she never imagined. at this french open she�*s taken a stance, refusing to speak to the press after matches. now she�*s pulled out of the tournament. osaka won her first match on sunday, but 24 hours later wrote this on twitter: "the best thing for the tournament is that i withdraw. i never wanted to be a distraction." osaka says she�*s suffered long bouts of depression since winning the us open three years ago, and she gets huge waves of anxiety before speaking to the media. now she says she�*s taking time away.

osaka chose not to speak to the press, she said, to preserve her mental health. tennis authorities had fined her and threatened disqualification. now some feel the sport could learn lessons. had the organisers known that she was suffering from depression, would they have gone out so strongly with a statement? probably not. i think saying that she was potentially going to be defaulted was always quite strong and maybe unnecessary. but here we are. and i think it�*s a real disappointment for the tournament that she�*s had to withdraw, but also for herself that she�*s been dealing with this for so long and no—one knew. last night, serena williams spoke out. she�*s just won the tournament�*s first night match. but she feels this has cast a shadow. i feel for naomi. i feel like, i wish i could give her a hug because i know what it's like. like i said, i've been in those positions. everyone is different and everyone handles things differently. so, you know, you just have

to let her handle it the way she wants to. the french tennis federation said they were sorry and sad for naomi osaka, and that they�*re committed to athletes�* well—being. this came about from osaka not wanting to talk. but now her and the sport will look for dialogue, as tennis tries to repair things with one of its greatest stars. joe lynskey, bbc news. meanwhile, afterjust two days, cameron norrie is the only brit left in the singles draw at roland garros. he has been in great form on clay this year and eased through his first round match in straight sets. but not much luck for the women. british number onejohanna konta could now be unseeded at wimbledon later this month after her first round exit. defeat to sorana cirstea extended her poor run. she has only won three matches all year. disappoinment too for heather watson, who also lost.

gareth southgate will name his england squad for this month�*s european championship at 5.00pm this afternoon, but manchester united forward mason greenwood won�*t be taking any part. the 19—year—old has ruled himself out because of an "underlying injury". he was expected to be in the 26—man squad after scoring 12 goals in 52 games for manchester united this season. meanwhile, the bbc understands that greenwood�*s united team—matejesse lingaard, who impressed this season on loan at west ham, has not been selected. that means there are five other players that will have to be trimmed. one of them could be a right—back, afterfour were named in the 33 last week. so trent alexander—arnold is competing with kieran tripper, reece james and kyle walker to be selected. england could also be concerned about harry maguire, who missed wednesday�*s europa league final through injury. jordan henderson as well hasn�*t played for liverpool since february because of injury,

but he too is aiming to make the final 26. it will be announced in a few hours�* time at 5pm. jadejones could make history at the tokyo olympics this summer as the taekwondo fighter goes for a third gold after being named in the team gb line—up. the 28—year—old won the title in both london and rio and will arrive in tokyo as the number one seed. she will be joined by world gold medallists bianca walkden and bradley sinden, as well as lauren williams and mahama cho. but there was disappointment for lutalo muhammed. having won bronze in 2012 and silver four years later, he missed out on a place in the team. that�*s all your sport for now. i�*ll have more in the next hour, joanna. nicola sturgeon will confirm "whether and to what extent" plans to further ease coronavirus restrictions can take place next week.

under the scottish government�*s covid route map, scotland was scheduled to move into level one restrictions from 7th june, but a recent spike in infections has forced ministers to keep the entire glasgow city council area under level three restrictions, meaning bars and restaurants can not serve alcohol indoors and get—togethers inside people�*s homes are also barred. an announcement from the first minister is expected later today. graham stewart reports. nothing says a bank holiday monday like a real replacement bus service. travel in and out of glasgow city is still forbidden under current restrictions, but that hasn�*t deterred people from heading out to enjoy one of the hottest days of the year so far. ministers are optimistic that

by the end of this week, the people of glasgow will finally be allowed to visit other households and drink inside pubs and restaurants. the further easing in the rest of mainland scotland might not apply immediately to all areas. we�*re looking very, very carefully at the data, right up until the day. i mean, you can imagine we like to see every bit of detail right up until we make a final decision on these matters. but of course, there are parts of the country, notjust glasgow, because it has been a lot of focus on glasgow, understandably so, but notjust glasgow, that gives us some cause for concern. and it may be that the whole country doesn�*t quite move to level one at the pace that was previously envisaged. i've said, and the scottish conservatives have said, from june 7th, when the country's expected to move to level one, that the whole country should go together. we've seen spikes in cases, and we've seen how they can be dealt with, with ensuring the testing and vaccinations are rapidly introduced to these areas. but a spike in certain postcodes in a major city shouldn't see the whole city or council area held back in tougher restrictions. a move down to level one would see soft play centres able to reopen. one business owner we spoke to said any delay to easing wouldn�*t be acceptable.

with soft play and glasgow, because of the guidance we�*ll only be allowed 30 children in it. so you�*re trying to tell me, scottish government, that 30 children can�*t go to a soft play, but 6,000 people can go outdoors into a... ..you know, drinking to watch the football. how quickly the country can move out of restrictions depends on the vaccine roll—out. at the hydro in glasgow, people complained of waiting up to three hours for a vaccine. the health board says the uptake has been higher than expected, but admits staffing numbers have been slightly less than usual due to the bank holiday. graeme stewart, reporting scotland. peru has announced the country�*s real number of coronavirus deaths is more than double what was previously thought. according to the new official figures, 180,000 people have died of covid in peru. that�*s now the world�*s highest death rate per head of population. sara monetta reports. families have been decimated by the coronavirus in peru�*s capital, lima. the second wave of the pandemic

is ravaging the country, and the death toll is rising. on monday, the government announced what most people already knew, that the actual number of covid—related deaths is much higher than previously acknowledged. the prime minister said it was the government�*s duty to make the revised data public, for transparency�*s sake. until now, the official statistics had the death toll at slightly over 69,000. the revised data put the number at more than 180,000. for months, frontline doctors and relatives had lamented that official numbers were not reflecting the reality they were leaving. translation: the dead are being taken out of the hospital every day. people are admitted to the hospital every day and we know nothing. relatives wake up here in the cold and sometimes we don�*t get the full report, that�*s the truth. experts say that the discrepancy was mostly due to the fact that

a death would be recorded as covid—related only if the patient had been tested. the problem is that peru doesn�*t test that much, a lot of antibody tests and other quick tests have been used, and sensibility has been very low. the new death toll could help understand better how the virus has spread in the country and how to prepare for future waves. but for frontline workers, the emergency is now, and they feel like they are losing this battle. translation: our health system does not meet the necessary conditions to care for patients. there has been no government support with oxygen, with intensive care beds. we do not have enough vaccines at the moment. the first line of care has not been reactivated. all this makes us the first country in the world in terms of mortality. a grim record for such a small country. sara monetta, bbc news.

birmingham city council says it won t be taking any payments in its new city centre clean air zone for another two weeks, even though it could charge older, more polluting vehicles from today. the decision was announced this morning just as the new charging regime was due to begin operation. our correspondent phil mackie gave us this update. the launch officially took place in birmingham this morning outside the library. two hours later, after we had heard there had been some problems with people going to the government website to pay 30 and had been redirected to baftas my clean air zone, we learned that birmingham was posing payments for two weeks, so that means that those people who do have to shoulder more polluting vehicles don�*t have to pay the fee

for the car for at least another fortnight. it is a little unclear as to why there was such a last—minute change of heart, but there are two suggestions that i have managed to get from birmingham city council as to why that might have happened. the first is that with the payment scheme the onus is very much on the driver. you don�*t drive into the zone and get an alert. it is very much on you to know that that is there and to then go online and pay it, so they felt a bit more time was needed for people to get used to that idea. the second reason is that there are exemptions for people who earn less than £30,000 a year and businesses based inside the zone, and they had a huge amount of applications for exemptions that came in at the very last minute last week and over the weekend, which they will need time to process. they say there are lots of other people that they think will qualify for an exemption who they would like to hear from over the next couple of

weeks. it has been posed for two weeks. it has been posed for two weeks. it has been posed for two weeks. it was a big lodge this morning, lots of people there, we have been trailing it for weeks, there are massive signs across the city centre whether you would enter the charging zone, but i guess it is probably a little bit —— embarrassing for birmingham, although they will tell you that it was planned all along, but it does look a little bit awkward considering they had this big lodge at seven o�*clock and by nine o�*clock things had gone completely on other direction. a vigil was held in north london last night for a flower seller who was stabbed to death close to his stall on saturday. described as "the flower man of islington", tony eastlake was a well—known face in his local community, and sold flowers in the same area for 40 years. leigh milner has more. flowers for the florist they all once knew. last night, dozens gathered to pay their respects to who they call the loveliest man to ever sell them flowers. applause.

tony eastlake started selling flowers more than 40 years ago at his stall in islington. now it�*s covered in messages from friends and family, after he was fatally stabbed on saturday afternoon. it�*s horrific. he was just, as everyone said, a localfixture. i buy my christmas wreath from him every year. a really nice, warm, friendly guy. we'd walk by him virtually every day, and just very, very sad because it was a nice place to get some flowers, and very sad to lose somebody like that so tragically and so unnecessarily. claire, who�*s lived here for 30 years, remembers him well. she came with a card for mr eastlake�*s family. you know, it�*s heartbreaking, because you could see from his whole demeanor and posture that he was just a lovely human being. well, this is where mr eastlake was found dead on saturday, just a short walk away from where his stall is. and witnesses say he was involved in an altercation with another man just before he was stabbed. now, in a statement, his family have said, "our hearts are broken forever at the loss of such a very special man.

we ask you now for your support in helping us to find the person, or people, who did this to our family, who took away a life so violently and unnecessarily." while the murder investigation continues, police are urging anyone who might know what happened on the day tony eastlake died, to come forward. leigh milner, bbc news. the headlines on bbc news: just five months old and making history — a baby with a devastating genetic disorder has become one of the first nhs patients to get a potentially life—saving gene therapy. a high—rise apartment block in east london where a fire broke out last month had serious fire safety issues including a faulty smoke ventilation system, an investigation finds. the heads of global bodies, including the world health organisation, urge the g7 to give extra vaccines

to third world countries, to halt the spread of variants. more migrants have crossed the channel by boat this morning, and been picked up by the border force. more than 3,700 people have made the crossing so far this year — that s double the figure for the same period last year. the government has once again pledged to crack down on the people smugglers organising the crossings, but human rights groups are warning that tough talking simply doesn�*t work. simonjones reports from dover. it has been an incredibly busy few days on the channel with the improved weather. we days on the channel with the improved weather.— days on the channel with the improved weather. days on the channel with the imroved weather. ~ ., , ., improved weather. we are seeing an increase in unaccompanied _ improved weather. we are seeing an increase in unaccompanied young i increase in unaccompanied young women and girls who are coming to the country through this route. that is worrying because they are coming in from what are known to be the

eritrean and vietnamese roots that are closely associated with modern slavery and sex trafficking. it is an issue that _ slavery and sex trafficking. it is an issue that divides the pic —— division. so far this year, more than 3500 migrants have reached the uk by boat. that figure is double the number we saw in the first five months of last year, for a bit of context, the people arriving this way are very visible, you can see them coming in here, but overall in them coming in here, but overall in the past year the number of people claiming asylum here fell by around a quarter. one of the brooches to make the crossing. the government says its new clapper immigration will break the business model of the people smugglers behind them, but one organisation working with the referee says this the desire for many migrants to cross the channel. we think we need to be approaching this from a totally different perspective. we have tried making it more and more difficult for people

but it doesn�*t stop people coming and risk people drowning at sea. we have to be working to find safer, legal ways for them to claim asylum so they don�*t have to make the choice to use people smugglers. the government has warned there is no quick fix, but if the crossings continue, so does the pressure on them to find solutions. the delayed sequel to the thriller a quiet place has become the biggest hit at north american box offices since the start of the covid—19 pandemic. a quiet place part ii made an estimated £34 million between friday and sunday. one of its stars, london—born actor noahjupe, has been speaking to louise minchin. she began by asking him about his famous mum. lots of people know your mum, as well, because she wasjulie in coronation street. yeah, i mean, i�*m so lucky to have my mum, you know, so to have her, you know, when i was growing up, going on sets at nine and stuff, to have her there supporting me was always very special. yeah, so nine�*s pretty young.

do you remember that — that was your first, what, tv orfilm role, was it? which one was it? it was a tv film role, actually — it was a song forjenny, about the 7/7 bombings. is jenny dead? i remember when it finished, i... i cried all the way home in the car. 0h! because you were going to miss them? yeah, i loved it. it was like a second home to me because everyone was so... it was such a community on set that when i got in the car and i realised that i wasn�*t going to get to go back to that community ever again, it was really kind of heartbreaking for me. and that�*s when i kind of knew that this job would be something that i would be passionate about and, you know, something that i would love doing. there are people out there. people worth saving. and for fans of a quiet place... so we prepare ourselves for scares. you�*re alongside emily blunt again. and just give us a quick insight — you know, it starts where?

it basically follows straight on from the events of the end of the last one. the safety has just gone out the window in this movie so you�*re just on number ten the whole time. oh, it�*s scary! what�*s it like being in it? the scariest thing about a quiet place is the fact... the jump scares. yeah. like, you know, when you think everything�*s ok, and suddenly this happens, right? and for us, because we�*ve read the script, we know what�*s happening, we know that something�*s coming. so it defeats the aspect of surprise. i have to say, filming it wasn�*t scary, but then when i went to the cinema and watched the first one, i was... i was so scared, i was like... even though you know what�*s going to happen. even though i know what�*s happening! iwas...

iwas, like, closing my eyes like this when i was watching it because i was so scared, so, yeah. for a quiet place, did you learn... did you learn actual sign language, as well? i mean, milli, who is also one of my best friends... millicent simmonds, who stars alongside you, yeah. millicent simmonds is, you know, i... immediately, we started emailing over the first — before the first a quiet place. and then once i met her, i was like, i need to speak to her, i need to talk to her. and obviously, there was a interpreter there so i could, but i wanted it to be just between us. so then i started to learn the alphabet of sign language and i�*d spell out the word that i wanted to say and she�*d sign it back to me. so it would take us an hour — it would take, like, half an hour for me to say, "how are you?" because i�*d be like, how...are you? that�*s a lovely skill to have, because you�*ll meet people in your life who you�*ll be able to talk to that you wouldn�*t,

you know, wouldn�*t be able to sign to before. i was on a plane with this old woman who was deaf and we were flying back to england or something, and she needed help. and this guy couldn�*t communicate with her. he was like, you know, trying to talk to her. and i rememberjust going over and saying, like, "do you know american sign language?" she was like, "yes." and then kind of talking to her and finding out what she needed and stuff, and helping the guy that was trying to help her. so, yeah, i mean, it�*sjust really cool to know and, you know, it�*s a different language, which is always exciting. i�*m just looking at some of the people you�*ve worked with, and it literally is the who�*s who of hollywood. so they think you killed her? no! so why else all of this, then? i don't know. sandy and caroline will probably be there, won�*t they? hey, jack, come sit here. in a sec. is it ok ifjack comes over? those men killed mom.

we've decided it'd be best if your auntie margaret i came and stayed with us. nicky needs a mother. we'll be strong. you can'tjust push the car hard. just amazing. craziness. yeah. some of them, um, you know, for example, cillian, who i�*ve recently worked with — i didn�*t actually really know a lot about him. the people that are left...what they've become. after the shoot, obviously, i was like, "right, i�*ve got to watch peaky blinders." now i�*m the biggest fan. ithink... i think i wouldn�*t have been able to speak to him, knowing some of the stuff he�*s done. you know, he�*s definitely now... i very much look up to him as an actor. i watched back today the night manager, some of the night manager, when you star alongside lots of superstars, but not least tom hiddleston. thank you very much, sir, for rescuing me. i never actually got to see the whole thing. i�*ve just seen my episodes because obviously, until recently,

i wouldn�*t have understood it and understood what was happening. he probably won�*t remember me. it would be interesting if i ever meet him again to be like, "oh, yeah, i was on a beach with you, throwing stones in the water." not only do you have this extraordinarily and hugely successful career — you, like anyone else, have to do exams. you need to get some gcses. how�*s that been? um... it�*s annoying and painful and...| haven�*t got much sleep recently, but, you know, i�*m...in it to win it. i�*m excited. 0k. it�*s been a real — listen — a real pleasure to talk to you. thank you very much indeed, noah. thank you. we are hearing that an off duty police officers is believed to have been injured by 29—year—old man sought in the connection with the death of a woman and child. people

have been to not go to the hopper�*s hill area of louth. lincolnshire police have issued a photograph of him and have said in a statement we are currently responding to an incident in hopper�*s hills where an off duty police officer has been injured. as injuries are not thought to be life—threatening. it is thought the individual responsible may be daniel bolton who is wanted in connection with the murder in the town last night. do not approach if you see him, instead, call 999. and avoid the hopper�*s hills area of the town. hello. highland scotland is the current holder of the uk�*s highest temperature of the year so far, after hitting 25.1 yesterday in kinlochewe. now, today, that temperature may be surpassed, and more probably in parts of england and wales, which will be a little warmer than yesterday. whilst most have the sunshine, this weather front close to northern ireland and western scotland is providing more cloud,

and we have already today seen a little rain across western parts of northern ireland. that will clear away and it will brighten up, but for the western isles, we will continue with cloud and patchy rain. elsewhere, plenty of sunshine but some misty low cloud on some of the eastern coasts, keeping it much cooler. elsewhere, temperatures will be in the rage of 20—25, may be up to 26. tonight, the low cloud and mist in eastern scotland and the northern isles becomes a bit more widespread. whilst most areas are dry and clear, we will have some thundery showers edging across the channel islands and into south—west england as the night goes on. for many of us, temperatures will be holding up in double figures. tomorrow, most areas will continue to see the sunshine but there will be more cloud across southern england into wales and the midlands later and northern ireland as we start to bring a weather system with some outbreaks of showery rain that could be thundery very gradually further north.

and there will still be parts of the coast of north—east england and eastern scotland will some low cloud and mist keeping it cooler. inland, it will be another warm to very warm day, but a bit breezier. this area of low pressure overnight and into thursday, with uncertain progress, takes the thicker cloud and chance of thundery rain further north. on thursday, whilst by no means certain exactly where that will be, whereas elsewhere, variable cloud, sunny spells, not as warm as it has been, but it will still feel warm in the sunshine. by friday it looks as if that system will have cleared away eastwards and we are left with variable cloud, sunny spells, most places with a dry day, but another weather system with thicker cloud and a chance of showery rain coming into northern ireland.

this is bbc news. the headlines just five months old and making history — a baby with a devastating genetic disorder has become one of the first nhs patients to get a potentially life—saving gene therapy. lincolnshire police say an off—duty police officer is believed to have been injured by daniel boulton. the 29 year old is wanted in connection with the murders of a woman and child in louth — and members of the public have been warned not to approach him. the heads of global bodies including the world health organization, urge the g7 to give extra vaccines to third world countries, to halt the spread of variants. heathrow airport opens a terminal for passengers arriving from "red list" countries. the system is design to keep travellers from high risk coronavirus destinations from mixing with other arrivals. in england, as thousands rush for a jab in west london,

there are further warnings that a rise in case numbers could delay the lifting of all restrictions later this month. i think at the moment, the data suggests that we need to be cautious, we mustn�*t lose all the gains that have been made over the last few months by a premature and hasty non—evidence—based loosening of restrictions. a high—rise apartment block in east london, where a fire broke out last month, had serious fire safety issues including a faulty smoke ventilation system, an investigation finds. a two—week delay to birmingham�*s clean air zone. high polluting vehicles will be charged to drive into the city centre, but payments won�*t start today as originally planned. and coming up this hour: naomi osaka pulls out of the french open saying she�*s suffered from depression since winning herfirst grand slam title in 2018.

a five—month—old boy from london has become one of the first children in the uk to be treated with a ground—breaking new gene therapy. arthur morgan, who has spinal muscular atrophy, is being treated with zolgensma. at a cost of £1.79 million pounds per patient it is the world�*s most expensive drug the nhs has negotiated a confidential discount for the treatment — which can increase life expectancy by as much as 40 years. the development means that potentially dozens of infants could be treated by the nhs. around 40 children are born with the most severe form of the disorder every year. the sma uk charity says newborns in britain should be screened for sma, as happens in other countries. the charity says early diagnosis

and treatment is vitalour medical our medical editor fergus walsh explains. this is the world�*s most expensive medicine. the list price of zolgensma is almost £1.8 million, though the nhs has negotiated a confidential discount, which will enable dozens of affected infants to be treated each year. five—month—old arthur is one of the first to benefit. he has spinal muscular atrophy — sma — a genetic condition which causes progressive muscle weakness. without treatment, those affected rarely live beyond the age of two. arthur is unable to lift his head, and struggles to move his arms and legs, but this single infusion should prevent further loss of nerve cells. it�*s been massive, massive ups and downs, but being able to now have the treatment is just going to be a game—changerfor us and give arthur the best

possible life he could have. around one in every 10,000 babies is born with spinal muscular atrophy. what is remarkable is that this one—off treatment may permanently stop any further decline in arthur�*s muscle function. so how does zolgensma work? it contains a healthy copy of a missing orfaulty gene called smn—1. this is inserted into a harmless virus. in the body, the virus delivers the replacement gene into the nucleus of motor neuron cells. this is essential to prevent those cells from gradually dying. the now healthy motor neuron cells start producing the missing smn protein, which is vital for muscle function. how's arthur? evelina children�*s hospital in london is one of a handful of centres in the uk which will offer this ground—breaking gene therapy. 20 years ago, a baby born with a severe form

of sma would have a very shortened life expectancy. we can now offer treatment that can really alter the outlook for these children. some other infants treated with zolgensma have seen their condition notjust stabilise, but improve. arthur�*s parents say they know it�*s not a cure, and they�*re simply delighted that he�*s being treated. fergus walsh, bbc news. we�*rejoined now by professor simon waddington who is professor of gene therapy at university college london. welcome and thank you forjoining us. talk through a bit more about the expectations of what this gene therapy can deliver because we were hearing there in the report that it�*s not a cure, but some people have seen the condition notjust stabilising but improving. i have seen the condition not 'ust stabilising but improving. i think fer us stabilising but improving. i think fergus made — stabilising but improving. i think fergus made an _ stabilising but improving. i think fergus made an excellent i stabilising but improving. i think. fergus made an excellent summary stabilising but improving. i think- fergus made an excellent summary of how the therapy works. the first

experiments were done in mice and the mice wouldn�*t lift more than about... after a single injection of this gene therapy, they were living for months or even a year or more. and so then ultimately then clinical trials were done where in the clinical trials we can see the injection at one in seven months of age and remember this is a single injection, three years later, many of these infants were achieving milestones that would never be achieved by infants with this disease that had received palliative care. so i think is worth bearing in mind that this is still very early days and very experimental medicine because we simply haven�*t seen infants that have survived so long with this therapy and so every single day is a milestone for us in

seeing how effective this therapy is. we hope it will actually last for many, many years, but as of yet, we simply don�*t know. 50. for many, many years, but as of yet, we simply don't know.— we simply don't know. so, this is obviously amazing _ we simply don't know. so, this is obviously amazing for— we simply don't know. so, this is obviously amazing for arter i we simply don't know. so, this is obviously amazing for arter and i we simply don't know. so, this is i obviously amazing for arter and his family that he is getting this treatment on the nhs, a six incredibly expensive, £1.79 million per patient. they have a confidential discount on that, but how viable is it that it gets rolled out for the approximately 40 kids who are born in this country every year with the most severe form of sna or i think there are probably three points that we should consider here in terms of cost. i three points that we should consider here in terms of cost.— here in terms of cost. i think we all aaree here in terms of cost. i think we all agree that — here in terms of cost. i think we all agree that way _ here in terms of cost. i think we all agree that way it _ here in terms of cost. i think we all agree that way it incredibly l all agree that way it incredibly expensive. the first point is worth balancing against the costs of current care because infants with this disease will require

round—the—clock care, obviously very intense care because they will never walk or crawl and will ultimately require ventilation and then they will not be able to eat for example. and so therefore, this intense care for their short lives is in itself incredibly expensive, totalling tens of hundreds of thousands of pounds for their lives and so actually, if you�*re thinking about therapy which possibly gives them a good quality of life for more than ten years, one has to bring this into consideration. the second point is that this is a single shot medicine, so it�*s quite unlike many of the drugs that have been given to people these days in that they would have to take it every day or every week for the rest of their lives, whereas this is actually the cost of the

drug for one single injection and of course, for the pharmaceutical companies to want to progress these sort of therapies, they of course have to have a return on their investments and so they have to choose a pricing somehow in this new world were a single injection will be this. so that health economics of this are new areas for us and then, the whole point is that this is a transformative medicine and there has been nothing before were a single injection can actually have such a profound difference to these infants who would otherwise not survive beyond the age of three or four years old. 50. survive beyond the age of three or four years old-— four years old. so, in terms of future development _ four years old. so, in terms of future development then i four years old. so, in terms of future development then and l four years old. so, in terms of- future development then and further applications for this sort of gene therapy, where are we actually are

and what is the potential? i therapy, where are we actually are and what is the potential?- and what is the potential? i think that another _ and what is the potential? i think that another thing _ and what is the potential? i think that another thing that _ and what is the potential? i think that another thing that relates i and what is the potential? i think i that another thing that relates back to the treatment is that, although this is a qualitative transformative medicine, it is still quite inefficient that they are receiving quite high doses of this therapy intravenously to be able to deliver working copies of the gene to the nervous system and so we are still quite early in the technology of gene therapies in terms of efficiency of delivery and you know, we would hope that the technological advances are such, and i know that we see these things are progressing all the time of the field, that we would hope that will be able to improve the gene vectors so that they will be ten or 100 times more efficient, which of course then would bring the cost down. but in terms of the entire field, this is

incredibly exciting and this was quite a watershed moment in gene therapy because this was an intravenous delivery to treat severe neurological disease and in fact, there are now many clinical trials across the world that have been started to treat other inherited genetic diseases were previously not only has not been a cure but in some cases there hasn't even been treatments and so it's an incredibly exciting time. flan treatments and so it's an incredibly exciting time-— exciting time. can it be used, is it onl for exciting time. can it be used, is it only for inherited _ exciting time. can it be used, is it only for inherited diseases? - only for inherited diseases? obviously, you can understand that it is about that? but is there a way of which the mechanism by which a primes the body to effectively cure itself, cannot be used for everything that goes wrong with our bodies? , . ., , , everything that goes wrong with our bodies? , . ., _ , ., ., bodies? genetic therapy is a whole field of technology _ bodies? genetic therapy is a whole field of technology and _ bodies? genetic therapy is a whole field of technology and medicine. i bodies? genetic therapy is a whole | field of technology and medicine. it actually, we have on the look in the

field a little wry smile about the fact that hundreds of thousands of people that receive the genetic therapy in the form of genetic vaccinations against coronavirus, so genetic therapies have been used and developed for a whole variety of conditions, so you may have reported on the genetic therapy of t cells for treating cancer and so that is using technologies of genetic modifier for our using technologies of genetic modifierfor our immune using technologies of genetic modifier for our immune system and it is being used to generate viral vectors to treat, to treat solid tumours and cancers. it is being used to treat cardiovascular diseases and so i think that actually, we are very much at the foothills of genetic therapies and we are going to see a lot of acquired diseases, coronavirus notwithstanding. it’s

acquired diseases, coronavirus notwithstanding. it's fascinating to talk to ou notwithstanding. it's fascinating to talk to you and _ notwithstanding. it's fascinating to talk to you and thank _ notwithstanding. it's fascinating to talk to you and thank you - notwithstanding. it's fascinating to talk to you and thank you indeed i notwithstanding. it's fascinating to l talk to you and thank you indeed for joining us on this day that arthur morgan has got that treatment on the nhs. some breaking news. we are hearing that the postmortem examination into the death of sarah everard who disappeared on the 3rd of march while walking home in south london has given her cause of death as compression of the neck. the metropolitan police have just put out that brief bit of news. you may well remember that she went missing on the 3rd of march after leaving a friend's house near clapham common to walk home and she was a 33—year—old marketing executive and she had been living at the time in brixton and she had been visiting a friend and went missing on her way home. on the 9th of march, when cousins, a police officer with the parliamentary and diplomatic ape permit detection unit was arrested

in kent on suspicion of her kidnapping and later on suspicion of her murder. and her remains were found in woodland near ashford in kent on the 10th of march. when cousins has been charged with kidnapping and murder. just to go back to that development that we are hearing. a postmortem examination has given her cause of death as compression of the neck. an off duty police officer is believed to have been injured by a 29—year—old man, who's wanted in connection with the deaths of a woman and child. members of the public have been warned not to approach daniel boulton, whom detectives want to trace following the deaths in the lincolnshire market town of louth. officers were called to an address on the town's high holme road police say there responding to an incident. last night they were called to address and the town were 26—year—old woman and a

nine—year—old son was found dead and we are hoping to speak to a reporter for a update shortly. the british medical association has joined calls for the government to delay a decision on lifting all remaining lockdown restrictions — which is due to take place in england on the 21st ofjune. some government scientific advisers continue to warn that while the uk's vaccination programme has been successful, it does not mean the battle against coronavirus is over. they suggest that even a short delay to the government's current road map could have a significant impact on the spread of the virus. world leaders have been told coronavirus vaccines must be shared with poorer nations to prevent richer countries from being hit by imported variants of the virus. in an open letter, the heads of four major global bodies warned of a "dangerous gap" in the availability ofjabs, with low—income nations receiving less than 1% of vaccines administered so far. meanwhile the world health organization has announced a new naming system for covid—19 variants using letters of the greek alphabet. global health leaders say the move

is to help simplify discussions and also to remove stigma from the names. earlier this month, the indian government criticised the naming of a variant first detected in the country as "the indian variant. " it's now known as the delta variant. the variants are of course a key concern of those advising against a total easing of restrictions later this month. here's the chair of the british medical association, dr chaand nagpaul. when you look at the conditions for coming out of...the road map conditions, one of those criteria was to make sure there were no concerns about new variants. so i think, at the moment, the data does suggest that we need to be cautious. we mustn't lose all the gains that we've made in the last few months by premature and hasty, non—evidence based loosening of restrictions. tony sophoclides is strategic affairs director at uk hospitality — the trade association for the hospitality sector. welcome and thank you forjoining

us. what you think about the prospect of another delay in easing the lockdown? firfit prospect of another delay in easing the lockdown?— the lockdown? first and foremost, the lockdown? first and foremost, the ublic the lockdown? first and foremost, the public health _ the lockdown? first and foremost, the public health agenda _ the lockdown? first and foremost, the public health agenda and - the public health agenda and objective has to become first and the government continues to stick with science and data as promised, but of course, any delay in the road map would have a devastating effect on an already fragile hospitality sector with a quarter of a million, i'm sorry, a quarter of hospitality venues still shot and those are opening and not able to turn a profit. a delay would inevitably push many businesses close to the cliff edge of failure and that would meanjob cliff edge of failure and that would mean job losses also.— cliff edge of failure and that would mean job losses also. what, i mean, obviously there _ mean job losses also. what, i mean, obviously there has _ mean job losses also. what, i mean, obviously there has been _ mean job losses also. what, i mean, obviously there has been a _ mean job losses also. what, i mean, obviously there has been a lot - mean job losses also. what, i mean, obviously there has been a lot of - obviously there has been a lot of support for businesses, but tell us more about the state of some of those businesses that you're talking about. $5 those businesses that you're talking about. �* , those businesses that you're talking about. a ., , ., those businesses that you're talking about. a ., , _ those businesses that you're talking about. a ., , ,, ., about. as i say, many are simply not

0 en. about. as i say, many are simply not onen- others — about. as i say, many are simply not open. others are, _ about. as i say, many are simply not open. others are, obviously - about. as i say, many are simply not open. others are, obviously running| open. others are, obviously running at trading levels that at best, 60% of 2019 equivalent and when margins were already tied then and so it is very difficult to make a business viable, let alone profitable and that's not least because of the fact that's not least because of the fact that social distancing restrictions are in place and that massively affects the capacity of venues as well as requiring extra staff for table service and to make sure the test and trace procedures are complied with and so, there's all of these different pressures which have amounted to make life difficult to say the least for the hospitality. as things start to settle and rebalance and sometimes people go back tojobs rebalance and sometimes people go back to jobs that they were unable to do for a while and leave a vacancies in other areas, also people leaving hospitality, what's your assessment of the job situation in the hospitality industry, because there has been some talk of

difficulty for people and for companies finding staff to fill positions?— companies finding staff to fill ositions? , ., ., companies finding staff to fill ositions? , . ., ., ., positions? yes, we have heard a lot of that, positions? yes, we have heard a lot of that. we — positions? yes, we have heard a lot of that, we know _ positions? yes, we have heard a lot of that, we know that _ positions? yes, we have heard a lot of that, we know that 8096 - positions? yes, we have heard a lot of that, we know that 8096 of - of that, we know that 80% of businesses that we surveyed were reporting vacancies for front of house roles such as waiting on bar staff, 85% for chefs and i think there are a number of factors that were coming into play as to why there are shortages there and many people went to different sectors during the lockdown and hospitality was first into lockdown and last out of lockdown and people havejust moved onto other things and aren't prepared yet to come back and we need to persuade them to come back but there are others that are more difficult to persuade such as those from non—british workers who returned back to their countries of origin during the crisis and either are finding it difficult to back because of the new immigration restrictions or because of the travel restrictions generally and

the cost for example from india to have to come back and have to quarantine etc. there is a lot of uncertainty that are putting many other former workers. yesterday, fi . ures other former workers. yesterday, figures for — other former workers. yesterday, figures for economic _ other former workers. yesterday, figures for economic growth - other former workers. yesterday, l figures for economic growth pushed up figures for economic growth pushed up the growth forecast for this year from 5.1% to just over 7% and there is a sort of sense that once the lockdown measures ease, things could potentiallyjust bounce back. but obviously, there will be companies that will be laden with death as a result of what they have been through —— debt. how do you predict the future for businesses in the hospitality sectors as they navigate their way out of this? it is their way out of this? it is interesting _ their way out of this? it is interesting that _ their way out of this? it is interesting that you - their way out of this? it 3 interesting that you should start with a point on growth because our part of the 2018 financial crisis —— my 2008 financial crisis showed that our sector could grow faster and would be in a good conditions should conditions be right and it could be

a catalyst in recovery and make recovery faster. but, there is a lot of debt there and so we need support to continue on finding a resolution for the wrench crisis which represents about two and a half billion pounds of rent debt in hospitality and so it would need what is the slippage of the 21st of june, will need an extension of the moratorium on rents but also many of those companies will be facing business rates bills at the beginning ofjuly and many of them without being able to get the business rate relief fund from their venues. they will be facing a great deal of of cost pressures and that is it if the 21st ofjune goes ahead, but there is still a great number of employees on furlough with increased contributions from the

businesses which we would hope that if there was a delay they would be addressed as well.— if there was a delay they would be addressed as well. thank you very much. sport and for a full round—up, from the bbc sport centre, here's austin halewood. inafew in a few hours' time will note the england squad for the european championships. gareth southgate makes his final selection of 5pm this afternoon but manages unity forward mason greenwood won't be taking part in the competition. the 19—year—old has ruled himself out because of an underlying injury and he was expected to be in the final 26 man squad after scoring 12 goals in 52 games for manchester united this season. meanwhile, the bbc understands that greenwood's united team—mate jesse lingard understands that greenwood's united team—matejesse lingard who impressed at west ham has not been selected as well and that means that there are five other players that will have to be trimmed from that initial squad. will have to be trimmed from that initialsquad. one will have to be trimmed from that initial squad. one of them could be

a right back after four were initial squad. one of them could be a right back afterfour were named in the 33 last week and so trent alexander arnold is competing with kieran trippier, rhys james and kyle walker to be selected and england may also be concerned about harry maguire who missed the europa league final through injury and jordan henderson there hasn't played for liverpool since february due to injury, but he also is aiming to make the final 26. and that's announced at five o'clock this afternoon. meanwhile, organisers of the french open said they feel sorry and sad that naomi osaka felt she had to withdraw from the tournament to protect her mental health. the world number two was fined for refusing to speak to the media after her matches. she said she wanted to protect yourself after suffering long bouts of depression since winning herfirst grand slam in 2018. osaka will now take time away from the game and she said she hopes to work with the sports's organises in the future about how to make things better for the players,

in the future about how to make things betterfor the players, press and fans. i things better for the players, press and fans. ., ., ., and fans. i feelfor naomi, i feel like i and fans. i feelfor naomi, i feel like i wish _ and fans. i feelfor naomi, i feel like i wish i _ and fans. i feelfor naomi, i feel like i wish i could _ and fans. i feelfor naomi, i feel like i wish i could give _ and fans. i feelfor naomi, i feel like i wish i could give her- and fans. i feelfor naomi, i feel like i wish i could give her a - and fans. i feelfor naomi, i feel like i wish i could give her a hug| like i wish i could give her a hug because i know what it's like. i said i have been in those positions. everyone is different and everyone handles things differently so you just have to let her handle it the way she wants to. jade just have to let her handle it the way she wants to.— just have to let her handle it the way she wants to. jade jones could taste history _ way she wants to. jade jones could taste history at _ way she wants to. jade jones could taste history at the _ way she wants to. jade jones could taste history at the olympics - way she wants to. jade jones could taste history at the olympics this l taste history at the olympics this year as a tae kwon do fighter goes for a third gold in the team gb team. she won in london and rio and will arrive injapan as the number one seed and she will be joined by compatriots as well as lauren williams. but there was disappointment for taylor muhammad as he won bronze in 2012 and silver four years later but he has a list missed out on selection. and that's all your support for now. and have won 30 more sport.

a dedicated terminal for anyone arriving on a flight from any of the 43 nations on the uk government's red list, has opened at heathrow airport. it follows criticism that passengers returning to britain from either red, amber or green list countries were being forced to queue in arrival halls together. our transport correspondent caroline davies reports. when international travel restarted last month, some couldn't wait to get away. but while this was the view in departures, in arrivals, passengers from green list, low risk countries, queued up in the same hall as arrivals from high—risk, red list countries. since mid—february, all arrivals from red list countries have had to stay in quarantine hotels for ten days to stop the spread of variants of concern. but before they go into isolation, some spent hours queued up alongside other, lower risk passengers. despite the separate queues, some passengers felt very uncomfortable being so close for so long. from today, any arrivals coming in on direct flights from red list

countries will be processed at terminal three. the terminal has been brought back to operation after being closed during the pandemic. while neither side will confirm who is paying for the reopening and running of the terminal, it is understood that the government is picking up a large part of the cost. but one of the biggest unions representing border force employees, the pcs, has said they are concerned the decision was taken out short notice, meaning that key social distancing procedures are not in place and that the terminal would be understaffed. the home office have said that border force is mobilising additional staff to help minimise queueing times for compliant passengers. whilst a government spokesperson said the new dedicated terminal at heathrow for arrivals from red list countries will enable passengers to be processed as safely and as efficiently as possible. international travel is likely to remain very different for a while to come, and heathrow have said they expect to have a dedicated red list terminalfor some time. caroline davies, bbc news.

kevin mills is the assistant group secretary for border force staff within the pcs union. thank you forjoining us. how is it going so far today? to thank you forjoining us. how is it going so far today?— going so far today? to be very honest, going so far today? to be very honest. we — going so far today? to be very honest, we haven't _ going so far today? to be very honest, we haven't heard - going so far today? to be very| honest, we haven't heard much going so far today? to be very - honest, we haven't heard much so i would take no news is good news and so we will wait and see. the numbers in reality should be fairly low because people are only travelling of they're british, irish or have residency here and you shouldn't be talking vast numbers. we have to say that the designated red zone is a step in the right direction, it is something that we have been arguing about but sadly seven —— or in several months now as people have been mixing together. our concern is it has taken three and a half months for somebody to pay for it and whoever is paying for it is not mentioning that but taxpayers are paying the lion's share and the fact

that we should have been going through management and being engaged to discuss south systems at work. will man the controls as we have done throughout the pandemic but this is a move now where we are dealing with people from the red zone and the government themselves have decided that these are high—risk passengers and therefore to some extent, we should had more dialogue and i am advised nationally that we have had no discussions nationally about safe systems of work at terminal three and that is where some of our real concerns are. what are your concerns and bad for your staff? indie what are your concerns and bad for our staff? ~ ., ., what are your concerns and bad for your staff?— your staff? we want to make sure, it's not just — your staff? we want to make sure, it's notjust our _ your staff? we want to make sure, it's notjust our staff, _ your staff? we want to make sure, it's notjust our staff, we _ your staff? we want to make sure, it's notjust our staff, we have - your staff? we want to make sure, it's notjust our staff, we have the | it's notjust our staff, we have the passengers arriving and anybody else employed on the planes we want to make sure that we are mitigation there to hopefully stop any form of contamination and disease and also, the safe distances, we are maintaining social distance as they come through controls and it's as

seamless as possible passing through immigration, through customs and event all of those coming into us into the hotel is in quarantine and it is to make sure the welfare of everybody involved in that area, but particularly our members is paramount when any are taken. indie particularly our members is paramount when any are taken. we are lookin: at paramount when any are taken. we are looking at pictures _ paramount when any are taken. we are looking at pictures of _ paramount when any are taken. we are looking at pictures of people _ looking at pictures of people looking at pictures of people looking pretty cramped in at heathrow, queueing pretty close together in large numbers. and there have been concerns around long queues and the risks of that. who's fault is that? and what is that? and fault is that? and what is that? and was it fault is that? and what is that? fific was it unavoidable? the fault is that? and what is that? air. was it unavoidable? the moment you introduce 100% checks on locator forms and predeparture testing, there are going to be queues. even if you only have a couple of minutes to question everybody in arrival, it will lead to queues of large numbers because the reality is that we have still seen significant numbers arriving in the united kingdom

throughout the pandemic, yes, it has nosedived significantly at airports, but there are still people travelling and have been throughout. queues were going to happen and sadly, i think queues are going to be with us going forward. what we have now done... passengers may be cleared a lot quicker and taken off to the hotels, but queues and designated terminals are probably going to be with us now for several months and possibly longer going forward. i don't think it will be just for now the other airports will look at it. this now it's time for a look at the weather with nick miller. hello. anotherfine, very warm day in the sunshine for many of us today. there is a weather front close to the west of northern ireland. it has produced a bit of rain so far today, but that clearing, brightening up in northern ireland, especially in the east. patchy rain into the western isles. elsewhere, though, it's dry but some low cloud and mist keeping parts

of the coast of north—east england, eastern scotland and it will be elsewhere, of course, in the sunshine, with temperatures up to 25, 26 celsius in the warmest spots today. further low cloud and mist in the northern isles, eastern scotland overnight. have a look at this. some showers, perhaps thundery rain into the channel islands and south—west england later in the night, and a night which for many of us has temperatures into double figures. now, tomorrow, this area of cloud with showers, perhaps thundery rain, gradually extends across more of southern england into wales, parts of the midlands and northern ireland as the day goes on. some low cloud and mist, parts of the coast of north—east england, eastern scotland keeping it cooler than it will be elsewhere where you get to see some of that very warm sunshine.

hello, this is bbc news with joanna gosling. the headlines: just five—months—old and making history — a baby with a devastating genetic disorder has become one of the first nhs patients to get a potentially life—saving gene therapy. lincolnshire police say an off—duty police officer is believed to have been injured by daniel boulton. the 29—year—old is wanted in connection with the murders of a woman and child in louth and members of the public have been warned not to approach him. the heads of global bodies, including the world health organization, urge the g7 to give extra vaccines to third world countries to halt the spread of variants. heathrow airport opens a terminal

for passengers arriving from �*red list�* countries. the system is design to keep travellers from high—risk coronavirus destinations from mixing with other arrivals. in england, as thousands rush for a jab in west london, there are further warnings that a rise in case numbers could delay the lifting of all restrictions later this month. i think at the moment, the data suggests that we need to be cautious, we mustn't lose all the gains that have been made over the last few months by a mature and hasty, non—evidence—based loosening of restrictions. a post—mortem has found sarah everard died from compression of the neck. the metropolitan police say the 33 year old's family ave been informed of the examination's findings and are being supported. a high—rise apartment block in east london where a fire broke out last month had serious fire safety issues, including a faulty smoke ventilation system, an investigation finds. a two—week delay to birmingham's clean air zone — high—polluting vehicles will be

charged to drive into the city centre, but payments won't start today as originally planned. a high—rise apartment block in east london, where a fire broke out last month, had serious fire safety issues including a faulty smoke ventilation system. 35 people had to be rescued from new providence wharf after an electrical failure resulted in a fire which spread three floors. a provisional investigation by the london fire brigade has discovered a detector failed to activate an automatic ventilation system and smoke poured into a corridor. our correspondent sean dilley has more. yes, sean dilley has more. we have to understand what happened yes, we have to understand what happened with the fire itself. it seems that there was a fault in the fused blocks —— box on an a4 flat. in the fire broke out, the paris get out of the window and smoke had

bellowed out the door to the flat that had been left open. if the censors had been working, that would have triggered the ventilation system, but it seems that was not the case. what happens when that smooth felt that whole way, it filled with smoke, the only escape route. there were concerns at the time in terms of the cladding that was on the outside of the building. the preliminary investigation said there was in a significant cost to there was in a significant cost to the external fire, there was in a significant cost to the externalfire, but there was in a significant cost to the external fire, but they do say that this should serve as a warning to any high rise building owner. there still needs to be a culture change. it is too late to see whether systems work after the fires have happened. the london fire brigade are saying that culture still needs to happen. police in lincolnshire are searching for a 29—year—old man in connection with the deaths of a woman and child in the market town of louth.

they say they have made an arrest of daniel boulton. our reporter harry parkhill is at the scene. you mentioned hubbard's hills. the sun is baking hot here today at basically a cherished location out in the lincolnshire walls. today, police have descended on it in force. a number of police guards and officers arrived here. to my left you can see an air ambulance. lots has been happening here in the last half an hour. a man has been seen being loaded into a police van by officers pursuing 29—year—old daniel boulton, who is wanted in connection with the deaths of a mother and son here in the town. a 26—year—old woman and a nine—year—old boy was

found stabbed to death over nights in the town. and now also believed to have been found used in the stabbing was found in the town centre. another young child also pointed the house earlier on is being looked after by police. this is a tourist destination, a number of families here gathering, police telling people to stay away from the area is not too long ago, but now i am being reassured by some of the officers here that it is safe to wander around. they have confirmed they have arrested some —— arrested someone in connection with this murder investigation. police are searching for teenage boys after a stabbing in birmingham at 7:30pm last night. world leaders have been told coronavirus vaccines must be shared with poorer nations to prevent richer countries from being hit by imported variants of the virus.

in an open letter, the heads of four major global bodies warned of a "dangerous gap" in the availability ofjabs, with low—income nations receiving less than 1% of vaccines administered so far. they said countries could see fresh lockdowns if people in developing nations are not vaccinated at a faster rate. earlier, our global affairs correspondent naomi grimley gave us this update. there is certainly a lot of frustration, i think, if you read between the lines of this op—ed that has gone into newspapers around the world, that developed countries have talked the talk when it comes to sharing doses, but did not actually come up with specific amounts that they will donate. that includes the uk, which has said, broadly, that it will donate the majority of its surplus to the developing world through covax, which is the global programme to try and get vaccines out to poorer countries, and yet they haven't actually put numbers on it or even a timetable. we have had some vague pledges. the us said it wants to get 80 million doses out to developing countries by the end of this year, and also the european union has said

100 million by the end of this year, but still very few specifics about how that will happen. there is a real crisis at the moment in africa because what happened was those countries were being supplied by india's serum institute. india then had to divert those doses domestically to help deal with the surge there. so we actually are now seeing many countries can't give their second doses to healthcare workers in africa and the who says they need 20 million in the next few weeks to fill that gap on second doses. rob yates, executive director of the centre for universal health at chatham house, says there's been a lot of talk, but not much action so far. we are seeing a lot of vague promises about freeing up vaccines once we've been vaccinated and good words, but it's not really being matched—up with action. we are going to be soon sitting on enormous stockpiles of vaccines

and potentially talking about booster vaccines in the uk, so i would be having my third shot potentially in september. really, this is outrageous that this is happening when frontline health workers in places like peru and malaysia are not being protected. john fleck has tested positive for covid at the scottish squad's pre—euro 2021 camp in spain. the scottish fa say that sheffield united player will not self—isolate and will travel to portugal with the rest of the squad for the friendly in portugal. the rest of the squad have been tested and they have all returned negative results. i am not a sports fan, and i have been told,

even though it is 2021, it is still euro 2020 because it was delayed. john fleck has tested positive, so he will not be joining john fleck has tested positive, so he will not bejoining in. peru has announced the country's real number of coronavirus deaths is more than double what was previously thought. according to the new official figures, 180,000 people have died of covid in peru. that's now the world's highest death rate per head of population. sara monetta reports. families have been decimated by the coronavirus in peru's capital, lima. the second wave of the pandemic is ravaging the country, and the death toll is rising. on monday, the government announced what most people already knew, that the actual number of covid—related deaths is much higher than previously acknowledged. the prime minister said it was the government's duty to make the revised data public, for transparency�*s sake. until now, the official statistics had the death toll at slightly over 69,000.

the revised data put the number at more than 180,000. for months, frontline doctors and relatives had lamented that official numbers were not reflecting the reality they were leaving. the reality they were living. translation: the dead are being taken out of the hospital every day. people are admitted to the hospital every day and we know nothing. relatives wake up here in the cold and sometimes we don't get the full report, that's the truth. experts say that the discrepancy was mostly due to the fact that a death would be recorded as covid—related only if the patient had been tested. the problem is that peru doesn't test that much, a lot of antibody tests and other quick tests have been used, and sensitivity has been very low. the new death toll could help understand better how the virus has spread in the country and how to prepare for future waves. but for frontline workers, the emergency is now, and they feel like they are losing this battle.

translation: our health system does not meet the necessary conditions to care for patients. there has been no government support with oxygen, with intensive care beds. we do not have enough vaccines at the moment. the first line of care has not been reactivated. all this makes us the first country in the world in terms of mortality. a grim record for such a small country. sara monetta, bbc news. more migrants have crossed the channel by boat this morning and been picked up by the border force. more than 3,700 people have made the crossing so far this year — that 5 double the figure for the same period last year. the government has once again pledged to crack down on the people smugglers organising the crossings, but human rights groups are warning that tough talking simply doesn't work. simonjones reports from dover. the latest arrivals. these migrants

were given life jackets and trotted over by the border force after they reached uk waters. it has been an extremely busy few days in the channel with calm seas in the channel with calm seas in the channel with calm seas in the channel with calm seas and warm weather. in channel with calm seas and warm weather. . . weather. in recent weeks we have seen not only _ weather. in recent weeks we have seen not only an _ weather. in recent weeks we have seen not only an increase - weather. in recent weeks we have seen not only an increase in - weather. in recent weeks we have i seen not only an increase in numbers overall, but an increase in the number of unaccompanied young women and girls who have come into the country through this route. that is worrying because they are coming in from what are known to beat the eritrean and vietnamese roots that are closely associated with modern slavery and soft —— sex trafficking. it is an issue that divides opinion. a protest against a number of people arriving was held at the weekend while at the previous weekend a group supporting migrants gather to air their views. group supporting migrants gather to airtheirviews. so group supporting migrants gather to air their views. so far group supporting migrants gather to airtheirviews. so farthis group supporting migrants gather to air their views. so far this year 3500 migrants reach the uk by boat. that figure is double the number we saw in the first five months of last year. the people arriving this way are very visible. you can see them coming in from here on the white cliffs, but overall in the past year

the number of people claiming asylum here fell by around a quarter. one of the boats used to make the crossing. the government says its new plan for emigration will break the business model of the people smugglers behind it, but one organisation working with refugees says this. the desire of many migrants to cross the channel. indie migrants to cross the channel. we think we migrants to cross the channel. 7 think we need to see approach this from a totally different perspective. we try to make it more and more difficult for people, but it doesn't stop people coming every rest people drowning at sea. we have to be working to find safe and legal ways for them to claim asylum so they don't have to make the choice to use people smugglers. the government — to use people smugglers. the government has _ to use people smugglers. the government has warned there is no quick fix, but as the crossings continue, so does the pressure on it to find solutions. the headlines on bbc news: just five—months—old and making history — a baby with a devastating genetic disorder has become one of the first nhs patients to get a potentially life—saving gene therapy. lincolnshire police say they have arrested a man wanted in connection

with the deaths of a woman and child in louth last night and the injuring of a police officer earlier today. a post—mortem has found sarah everard died from compression of the neck. the metropolitan police say the 33—year—old's family ave been informed of the examination's findings and are being supported. two serving members of the army have been charged with firearms offences after being accused of trying to sell ammunition. kirtland gill, 40, and rajon graham, 32, both from berkshire, were arrested following an investigation by the metropolitan police's flying squad. birmingham city council says it won't be taking any payments in its new city centre clean air zone for another two weeks, even though it could charge older, more polluting vehicles from today. the decision was announced this morning just as the new charging regime was due to begin operation. our correspondent phil mackie gave us this update. the launch officially took place at seven o'clock this morning

outside the library. they pumped out some smoke from the roof of the library to sort of symbolise the pollution that they were hoping to end. two hours later, after we had heard that there had been some problems with people going to the government website to pay the fee and been redirected to bath's clean air zone, we learned that birmingham was pausing payments for two weeks. so that means those people who have those older, more polluting vehicles that don't meet emission targets don't have to pay an e8 daily fee if they are driving a car or a van, £50 for a coach or a lorry, for at least another fortnight. it is a little unclear as to why there was such a last—minute change of heart, but there are two suggestions that i have managed to get from birmingham city council as to why that might have happened. the first is that, with the payment scheme, the onus is very much on the driver. you don't drive into the zone and get an alert to tell you have entered it and you have to pay a fee, it is very much

on you to know that that is there and to then go online and pay it, so they felt a little bit more time was needed for people to get used to that idea. the second reason is that there are exemptions for people who earn less than £30,000 a year and businesses based inside the zone and they had a huge amount of applications for exemptions that came in at the very last minute, last week and over the weekend, which they will need time to process. they actually say that there are lots of other people they think would qualify for an exemption who they would like to hear from over the next couple of weeks, so it has been paused for two weeks. it was a big launch this morning, lots of people there. we have been trailing it for weeks. there are massive signs across the city centre, everywhere that you would enter that charging zone. i guess it is probably a little bit embarrassing for birmingham. they will deny that. they will tell you that it was all planned all along and they didn't want to charge anybody, and i'm sure that's true, but it does look a little bit awkward considering they had this big launch at seven o'clock and by nine o'clock things had sort of gone completely

in the other direction. events having ta ken events having taken place in tulsa to commemorate an event were up to 300 black people were killed. joe biden has called on america to get rid of systemic racism. a vigil was held in north london last night for a flower seller who was stabbed to death close to his stall on saturday.described as "the flower man of islington", tony eastlake was a well—known face in his local community, and had sold flowers in the same area for a0 years. police are treating his death as murder. the delayed sequel to the thriller �*a quiet place' has become the biggest hit at north american box offices since the start of the covid—19 pandemic. �*a quiet place part ii' made an estimated £34 million between friday and sunday. one of its stars, london—born actor noahjupe, has been speaking to louise minchin. she began by asking him

about his famous mum. lots of people know your mum, as well, because she wasjulie in coronation street. yeah, i mean, i'm so lucky to have my mum, you know, so to have her, you know, when i was growing up, going on sets at nine and stuff, to have her there supporting me was always very special. yeah, so nine's pretty young. do you remember that — that was your first, what, tv orfilm role, was it? which one was it? it was a tv film role, actually — it was a song forjenny, about the 7/7 bombings. is jenny dead? i remember when it finished, i... i cried all the way home in the car. 0h! because you were going to miss them? yeah, i loved it. it was like a second home to me because everyone was so... it was such a community on set that when i got in the car and i realised that i wasn't going to get to go back to that community ever again, it was really kind of heartbreaking for me. and that's when i kind of knew that this job would be something that i would be passionate

about and, you know, something that i would love doing. there are people out there. people worth saving. and for fans of a quiet place... so we prepare ourselves for scares. you're alongside emily blunt again. and just give us a quick insight — you know, it starts where? it basically follows straight on from the events of the end of the last one. the safety has just gone out the window in this movie so you're just on number ten the whole time. oh, it's scary! what's it like being in it? the scariest thing about a quiet place is the fact... the jump scares. yeah. like, you know, when you think everything's ok, and suddenly this happens, right? and for us, because we've read the script, we know what's happening, we know that something's coming. so it defeats the

aspect of surprise. i have to say, filming it wasn't scary, but then when i went to the cinema and watched the first one, i was... i was so scared, i was like... even though you know what's going to happen. even though i know what's happening! iwas... iwas, like, closing my eyes like this when i was watching it because i was so scared, so, yeah. for a quiet place, did you learn... did you learn actual sign language, as well? i mean, milli, who is also one of my best friends... millicent simmonds, who stars alongside you, yeah. millicent simmonds is, you know, i... immediately, we started emailing over the first — before the first a quiet place. and then once i met her, i was like, i need to speak to her, i need to talk to her. and obviously, there was a interpreter there so i could, but i wanted it to be just between us. so then i started to learn

the alphabet of sign language and i'd spell out the word that i wanted to say and she'd sign it back to me. so it would take us an hour — it would take, like, half an hour for me to say, "how are you?" because i'd be like, how...are you? that's a lovely skill to have, because you'll meet people in your life who you'll be able to talk to that you wouldn't, you know, wouldn't be able to sign to before. i was on a plane with this old woman who was deaf and we were flying back to england or something, and she needed help. and this guy couldn't communicate with her. he was like, you know, trying to talk to her. and i rememberjust going over and saying, like, "do you know american sign language?" she was like, "yes." and then kind of talking to her and finding out what she needed and stuff, and helping the guy that was trying to help her. so, yeah, i mean, it'sjust really cool to know and, you know, it's a different language, which is always exciting. i'm just looking at some of the people you've worked with,

and it literally is the who's who of hollywood. so they think you killed her? no! so why else all of this, then? i don't know. sandy and caroline will probably be there, won't they? hey, jack, come sit here. in a sec. is it ok ifjack comes over? those men killed mom. we've decided it'd be best if your auntie margaret. came and stayed with us. nicky needs a mother. we'll be strong. you can'tjust push the car hard. just amazing. craziness. yeah. some of them, um, you know, for example, cillian, who i've recently worked with — i didn't actually really know a lot about him. the people that are left...what they've become. after the shoot, obviously, i was like, "right, i've got to watch peaky blinders." now i'm the biggest fan. ithink... i think i wouldn't have been able to speak to him, knowing some of the stuff he's done.

you know, he's definitely now... i very much look up to him as an actor. i watched back today, the night manager, some of the night manager, when you star alongside lots of superstars, but not least tom hiddleston. thank you very much, sir, for rescuing me. i never actually got to see the whole thing. i've just seen my episodes because obviously, until recently, i wouldn't have understood it and understood what was happening. he probably won't remember me. it would be interesting if i ever meet him again to be like, "oh, yeah, i was on a beach with you, throwing stones in the water." not only do you have this extraordinarily and hugely successful career — you, like anyone else, have to do exams. you need to get some gcses. how's that been? um... it's annoying and painful and...| haven't got much sleep recently, but, you know, i'm...in it to win it. i'm excited. 0k. it's been a real — listen —

a real pleasure to talk to you. thank you very much indeed, noah. thank you. it's been very warm for the past few days, so let's take a look at how some people were cooling down yesterday over 100 feet above the streets of london. this sky pool is near the us embassy in nine elms, just south of the thames, and is believed to be the world's first transparent pool built between two skyscrapers. swimmers can enjoy views of parliament and the london eye while they swim their lengths of the 25—metre pool. the one catch is you have to be a resident to use it. in a moment ben brown will be here with the news at one, but first it's time for a look at the weather with darren bett hello, there. it is another warm and sunny day for most of us today. on the satellite picture we can see more cloud in the far north of scotland, northern ireland. that is

moving away. a great deal of that low cloud coming onto the north—east coast. generally, dry and sunny with temperatures getting up to 26 degrees. the highland is not expected to be the hot spot today, there is a bit more cloud there and there is a bit more cloud there and there could be a few showers this evening, which will fade away overnight. continuing to see low cloud in the northern isles, moving into the central belt of scotland as well. showers in the first south—west of england and the channel islands tonight. for many it will be a dry, clear and warm nights. showers developing in the south—west, pushing their way up to wales, they could be happy country, they will eventually move into the west midlands, as well. ahead of that, lots of sunshine to come and the highest temperature shall be ahead of them showers across north—west england, the midlands come into the site is dependent before we get some showers in the evening. killer on the north sea coast and with a stronger wind. we

do have the sunshine it will be strong with high uv levels once again. wednesday sees the peak of the temperatures. this weather and continues to bring some showers northwards during the evening and overnight. still some heavy ones leftover first on thursday, but before they become lighter and drift further northwards into scotland. it may well be cloudy further south for england and northern ireland with some sunshine coming through. temperatures will be as high on thursday but still a pleasantly warm day for the south—east of england and east anglia in particular. by the evening we could start to see some showers developing in the far south of england. this could contain some thunder as they develop and spread today —— their way northwards into the midlands by friday morning. briefly into eastern scotland before moving away to the north sea. then more sunshine arrives on friday. it clouds over more in the west, particularly in northern ireland.

those temperatures a bit lower than today, but nearer normal for this time of year.

a revolutionary gene therapy is given to a baby at a hospital in london. atjust five months old, arthur morgan makes history after being treated for a spinal disorder with the world's most expensive drug. being able to now have the treatment is just going to be a game—changer for us, and give arthur the best possible life he could have. we'll hear from our medical editor on the implications of this groundbreaking treatment. also this lunchtime... heathrow airport opens a terminal specially for people arriving from red list countries, after concerns they had been too close to other passengers the doctors' union — the bma — urges caution over the full lifting of covid restrictions in england later this month.