this is bbc news. i'm ben brown with the latest headlines for viewers in the uk and around the world. a warning from the us vice president on a visit to central america — don't come to the united states. i want to be clear, to focus that make two people in this region who think about making the dangerous trek to the united and mexico border, do not come. the first new treatment for alzheimer's for nearly twenty years has been approved by us regulators. this will give hope to the people who have not had any hope for a very long time. there are patients and participants in my trials were desperate to find something that will help. thousands of british holidaymakers are rushing home from portugal — as new covid

restrictions come into force. and from bookseller to astronaut. amazon founderjeff bezos is embarking the us vice president kamala harris, who's visiting guatemala, has urged its citizens not to come to the united states. this is herfirst stop on a regional tour aimed at tackling the undocumented mass migration to america right at the source. ms harris and the biden administration are pledging $310 million in immediate humanitarian aid. in addition, there will be long—term investments worth four—billion dollars to boost development and security

across the region. and it's notjust money — last week the us said it would send 1.5 million vaccines doses to guatemala and mexico. but consider this: one usaid study looking into programmes in guatemala found that from 2006 to 2011, incomes rose less in places that got us funding, than in similar areas that received nothing. and the numbers heading north keep growing. in april, us border agents encountered nearly 180,000 migrants at the border — that's a 20—year high. i want to emphasise that the goal of our work is to help what islands find hope at home. at the same time, i wanted to be clear to folks in this region who are thinking about making that dangerous trek to the united states— mexico border, do not come.

0ur correspondent will grant has been following developments from mexico city, which is where the vice president is heading next. he says there's no guarantee the aid promised will help migrants stay in these countries. there is a lot of discussion of anti—corruption efforts being taken, taking place in guatemala and in the countries of central america more generally to make sure the funds of the recipient and are not as kamala harris put it, into corrupt hands. it was interesting to watch the president it is hard to do in reality than to simply announce. it was interesting to watch the president alejandro giammattei become very defensive when he was questioned about his administration's record in terms of corruption, he said his administration had not meddled with anti—graft prosecutors. it is a lot of money and the record of these countries and the trust of the population in the politicians is very low and very poor. so it is an extremely difficult thing for the administration to do properly if it

intends to put this large amount of money in with the intention of incentives and jobs and so on to make sure that people do not head north. i've been speaking to ariel ruiz soto, policy analyst at the migration policy institute in california. he says the message "don't come" isn't as simple as that. the success for the mission to guatemalan and then afterwards for mexico will be measured by the way the outcomes that follow after the visit. the boy key point in what amal to build enough political motivation and also set up structural systematics drug is for cooperation to make sure that the future plans for the development assistance but also for migration management in mexico and what i'll go through. i think that is what will be the measuring stick here when we think about migration into america. 0bviously migration into america. obviously there are many different barriers in the way. one of them is as the reporter

mentioned, includes trying to understand the programmes but by targeting, better targeting us assistance you can try to get to some of the focus and the population is most likely to migrate. fix, the population is most likely to migrate-— the population is most likely to miarate. �* ., ., , , , to migrate. a of money is being offered as _ to migrate. a of money is being offered as money _ to migrate. a of money is being offered as money the _ to migrate. a of money is being offered as money the answer. offered as money the answer here was to mark money alone is not the answer.— not the answer. problems that come afterwards _ not the answer. problems that come afterwards may - not the answer. problems that come afterwards may be - not the answer. problems that | come afterwards may be telling to shift the flow of migration from certain populations. i mentioned potentially with women or children in specific areas of what a mylar, those programmes can be helpful and the more that we do in the united states and in the region together to make that a core responsibility you can define and have some decrease in regular migration flows. in total, research has shown us that for development to really decrease migration in the long—term it will have to be several years before that will happen. so we must consider our

expectations from the beginning when talking about particular groups and areas.— when talking about particular groups and areas. briefly, what other key factors _ groups and areas. briefly, what other key factors are _ groups and areas. briefly, what other key factors are driving - other key factors are driving these migrants? in what mahler, these migrants? in what mahler, the poverty, malnutrition, insecurity and corruption. in el salvador it tends to be gang violence and more political stability but overall the number one factor for most places is violence and insecurity, especially in places and countries that do not have protection but they do in urban settings. a controversial new treatment for alzheimer's has been approved by regulators in the us. aducanumab targets the underlying cause of the disease rather than just easing symptoms. patient groups have campaigned for its approval — but it's a contentious decision — some experts and the fda's independent advisory committee opposed its approval. our medical editor

fergus walsh reports. this is an historic moment in the battle against alzheimer's. for the first time, a drug has been approved which tackles notjust the symptoms but the underlying cause of this devastating disease. aducanumab is not yet licensed in the uk and available only as part of a clinical trial — like here, at the national hospitalfor neurology, in central london. aldo ceresa, who's 68, was diagnosed with alzheimer's ten years ago and had to stop working as a surgeon. he receives aducanumab every month, via infusion, and is certain it's helped him. i felt that i wasn't getting so mixed up. my cognitive tests were improving quite markedly. two years ago, aducanumab was written off as a failure and the trial aldo was taking part in was abandoned.

but the manufacturers, biogen, analysed more data and concluded those on the highest doses had better cognition, memory and language. this is the brain of someone with early alzheimer's. the red areas show a build—up of amyloid, a protein which can form toxic deposits. this is the same individual after a year of aducanumab — significant amounts of amyloid have been cleared. so, this drug was approved on the basis of this drop in amyloid that you are seeing here. the doctor who is leading the clinical trials of aducanumab in the uk is delighted. this is a pivotal moment for the alzheimer's research community. this will give hope to the people who haven't had any hope for a very long time. there's patients and participants in my trials who are desperate to find something that helps.

in recent years, over 100 promising alzheimer's drugs have flopped, so to now have a medicine that can potentially slow the disease is a huge moment and will encourage scientists to redouble their efforts and find even better treatments. aldo has been back on aducanumab for six months and says he's already beginning to feel the benefits. i've noticed that i'm getting less confused. although it's still there, it's not quite as bad. and i'm just feeling that bit more confident now. aducanumab is suitable only for those with mild alzheimer's, when damage to brain function is still limited. it could take more than a year before uk regulators decide whether to approve the drug. if they do, demand here will be enormous. the us government says it has recovered $2.3 million worth of cryptocurrency, paid to the hackers who shut down

the colonial pipeline's computer systems. investigators seized about 63 bitcoins from the hacker group based in russia. the ransomware attack last month led to massive shortages at gas stations and sparked panic—buying. colonial pipeline said it had paid the hackers nearly $5 million to regain access. but the justice department says now "the tables have turned". thousands of british holidaymakers have been rushing to get home from portugal, before the latest quarantine rules come into force in the early hours of tuesday morning. anyone who doesn't make it back before 4am will have to quarantine for up to ten days on their return, because portugal has now been taken off the green list and is in the amber category — a decision widely criticised by travel companies and tourists alike. 0ur correspondentjenny hill is in albufeira. it's not how they thought

their holiday would end. faro airport in the algarve today, a last chance for those who don't want to quarantine to get home. we had to change our flight from wednesday to today and it cost us £140 each, which is disgusting. for esther and audrey, it's been a stressful weekend. like many, they struggled to secure the test they needed for the flight home. we paid more money getting here than what we actually paid for the holiday. most here thought portugal was a safe bet, until on thursday, the uk government suddenly decided otherwise. a bit of a blow, really, it came out of nowhere. we just had to bring our flight forward by a couple of days. so, we were meant to be coming back on wednesday. i need to go to work. it's not been easy. spent all weekend worrying about how to get back. - there are some 45 flights back to britain today. there were more over the weekend, as holiday—makers scrambled to get home in time. it's orderly today but the overwhelming sense is one of disappointment,

notjust for those who've had to cut their holidays short but perhaps more so for this country's tourism industry. it's just a few weeks since british tourists and hope returned to the algarve after a pandemic year. the uk is portugal's biggest tourism market. so the decision has left this country furious, frustrated and baffled. the algarve is very low in cases. yet in lisbon and maybe porto, but lisbon at the moment, i think there's maybe one area, there's been a little rise but not here. i mean, everybody comes with a negative test, everyone goes home with a negative test, so what is the problem? queueing up for those tests today, alison and herfamily, who'd come to see granny and grandad for the first time in two years. they fly home tomorrow, which means quarantine. yes... quarantine now. six hours after the deadline because we fly at 10:10. how do you feel about that? not happy about it.

well, we're both key workers, actually. i'm a paramedic, amy's a care in the community. they need us out there. making the most of it, rob and betty, who found out portugal was going onto the amber list ten minutes after they'd checked into their algarve hotel. i'm self—employed and i run a business, sojust a bit of panic, really, of what to do. you know there's a risk coming away, itjust... i'd not thought about this risk as much. this country can guarantee sunshine and hospitality but it's no longer sure of its summer season. stay with us on bbc news. still to come, concern of the level of covid—19 deaths in india. fears that the number of fatalities is far higher than

official statistics. the day the british liberated the falklands. and by tonight, british troops had begun the task of disarming the enemy. in the heart of the west german capital, this was gorby—mania at its height. the crowd packed to see the man who, for them, has raised great hopes for an end to the division of europe. it happened as the queen moved towards horse guards parade for the start of trooping the colour. gunshots the queen looks worried but recovers quickly. as long as they'll pay to go and see me. _ i'll get out there _ and kick 'em down the hills. what does it like to be the first man to cross the channel by your own power? it feels pretty neat.

it feel marvellous, really. this is bbc news. the latest headlines: the us vice president kamala harris has warned guatemalans against coming to the united states, saying they would be turned back at the border. the first new treatment for alzheimer's for nearly twenty years has been approved by us regulators. india's second covid—19 wave initially ravaged cities but it soon reached rural parts of the country. many died due to poor or no access to good healthcare. most of them were not even able to get a covid test done. now experts believe that the number of deaths in rural india is much higher than official statistics. the bbc�*s vikas pandey and anshul verma visited

two villages in the northern indian state of uttar pradesh to investigate alleged under—reporting of covid—19 deaths. the visuals you are seeing are from the northern indian city of allahabad. locals there say that these are the graves of people who died of a covid in april. when crematoriums ran out of space, people just buried their dead by the river. we are driving to some villages in uttar pradesh state to see how covid has devastated rural india, and how hundreds of deaths in those areas went unreported. but first let's talk about allahabad. 0fficials there say that seeing shallow graves is not an uncommon sight because many hindu communities follow the practice of burying

their dead by the river. but people and journalists we spoke to told us that the numbers are much higher this year. 0urfirst stop is kushaliya, a village which is barely 100 kilometers from the national capital of delhi. and it has reported dozens of dead. so we are going to talk to people in the village and also members of the village council.

we are going to speak to two people who on a single day, they lost their mother and elder brother to covid.

after hearing those heartbreaking stories in kushaliya village, we are now going to another place called kanauja and we have been told similar things happened there. dozens of people died without getting a covid test done or getting a hospital bed. people in the villages we visited and many others want officials to acknowledge these missing covid deaths. they believe that those who struggled to get a hospital bed or oxygen and even a covid test deserve some dignity in death.

police in london, ontario, say that five family members who were run over by a driver on sunday night were targeted because they were muslim. four members of the family died from their injuries. only a nine—year—old boy survived. officials say the attack was premeditated. police have detained a 20—year—old in connection with the attack. with the new academic yearjust months away, universities are sifting through applications to offer places. last year, the us recorded a drop in student visa applications and this year the number has fallen even further. as sarah toms reports, the pandemic is partly to blame but many students also worry about rising violence against people of asian descent. singapore student dai xiang rong has always dreamed of studying in the usa. he worked hard and got a coveted place at yale university to take computer science and economics.

but the 19—year—old has had second thoughts. for a lot of people, especially asians like myself and my friends, you have seen the recent news of anti—asian racism and attacks, especially in the us and other countries. it's quite a deterrent to our dreams to pursue english education and it might be because of the pandemic, but beyond that i think there was some sort of racism that was already ingrained in a lot of people's minds. foreign student enrolment at us universities has dropped 16% between the autumn of 2019 and 2020. the stats on new international students look even grimmer, with a 43% drop. health concerns are a major reason as the us has been hit hard by covid. but racism and violence against ethnic asians are also causing many applicants to pause. some people directly blame the anti—china rhetoric

of former us president donald trump. kung flu. attacks against asians in the us, including the murders of six women in atlanta, have sent shock waves through asia. many asian students are still very willing to study abroad despite of the racism, so what they do is they tend to segregate, and they tend to segregate in the ethnic communities, so this will to some extent intensify the racism. for universities, foreign students like these ones here in singapore bring in plenty of money by paying higher tuition fees. beyond money, they also bring diversity, fresh ideas, and connections for the future. many experts believe western countries risk losing their competitive edge if foreign students feel unwelcome. missing out on all of that will have repercussions

for not only universities but entire economies. as for xiang rong, he is willing to take the risk to pursue his dreams. sarah toms, bbc news, singapore the founder of amazon, jeff bezos, says he and his brother will travel into space next month on his rocket company's first sub—orbital sightseeing trip. a third seat on the spacecraft is being auctioned off. 0ur science correspondent rebecca morelle reports. heading to the edge of space. this is the new shepard rocket. so far, it's only flown with mannequins. now it's ready for its first real passengers, and jeff bezos, who owns the spacecraft, has announced he will be on board, along with his brother. it changes your relationship with this planet, with humanity. it's one earth. i want to go on this flight because it's a thing

i've wanted to do all my life. the rocket system will reach 100 kilometres above the earth, where passengers will experience about three minutes of weightlessness, and see the blackness of space and earth's covered horizon. in the future, anyone will be able to take a ride for around £150,000 a ticket. and it's not the only company to test if space tourism is commercially viable. sir richard branson's virgin galactic space plane is expected to carry paying customers by the end of the year. spacex. separation confirmed. and seats on elon musk�*s spacex capsule cost millions to go into low earth orbit. for now, these trips are only for the super wealthy, but experts say prices should drop. for the young people today particularly, it will become a reality that they could save up some money and choose to go to space, not every day, but it could be something that you could choose to spend a chunk of your savings on, and experience a few

minutes of weightlessness. mission control: landing gear deployed. the new shepard flight is due to take place injuly. the capsule carrying jeff bezos and his brother will descend back to earth with parachutes, marking the start of a new era in space tourism. rebecca morelle, bbc news. before we go, when the local neighbourhood dog is lost, they are usually found at the nearby park or maybe in the neighbours backyard. but not always. a group of sailors sailing through the arctic found the dog. thankfully, they rescued the pup and brought it on board. they eventually found the owner in a nearby village who said that her dog had been missing for a week. there we.

you can reach me on twitter. thank you for watching. hello there. it's been a warm start to the new week. quite a bit of cloud around on monday, but i think for today, it's looking sunnier across the board. it's going to stay warm for the rest of this week, and in fact, we're going to start to import some tropical air across the country, so it's going to feel quite humid. there will be further patchy cloud and rain across northern and western areas as low pressure will always be nearby. the setup into tuesday, higher pressure to the south, lower pressure to the northwest, so it does mean we'll start off rather grey for much of scotland and northern ireland through this morning with some patchy, light rain and drizzle. but conditions will start to improve for northern ireland — skies brightening up here and across northeast scotland. elsewhere, after a bit of early cloud and miss, it's going to be a sunny day, and it's going to feel

warmer with more sunshine around. we could see 25 degrees across southeast england, 22 or 23 for the northeast of scotland. there could be just the odd shower here and there, but most places will be dry. now, as we head through tuesday night, we'll see further cloud returning to scotland and northern ireland. patchy rain here, some coastal fog, too.

but it'll be a bit breezier across the board. windier in the far northwest of scotland, where we'll have most of the rain. but you can see it is another warm day. low to mid 20s celsius for england and wales. factor in the humidity, of course, it's going to feel warmer than that, and nights are also going to be warm and muggy. could see something a little bit fresher across scotland, northern ireland on friday. otherwise, it's going to remain warm with some sunshine into the weekend.

this is bbc news — the headlines:

the us vice president kamala harris has warned guatemalans against coming to the united states, saying they would be turned back at the border. speaking during a visit to guatemala she said the trip north was extremely dangerous and would mainly benefit people smugglers. the first new treatment for alzheimer's for nearly twenty years has been approved by regulators in the united states. aducanumab targets the underlying cause of alzheimer's. the drug, given as a monthly infusion, targets amyloid — a protein that builds up in the brains of alzheimer's patients. thousands of british holidaymakers have been rushing to get home from portugal — before the latest quarantine rules come into force in the early hours of tuesday morning. anyone who doesn't make it back before four am local time will have to quarantine for up to ten days.

now on bbc news, it's hardtalk.