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tv   Click  BBC News  October 3, 2021 4:30am-5:01am BST

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holding demonstrations across the united states. they are opposed to a new law in texas that severely limits access to abortions in the state. there are also wider fears the supreme court will soon rule abortions nationwide are illegal. a fire has destroyed hundreds of homes in ireland and honduras. —— on the resort island of guanaja. hundreds were forced to evacuate with the honduran air force sent to help contain the fire. at least four people were injured before it was brought under control. demonstrations against the brazilian presidentjair bolsonaro are taking place in dozens of towns and cities across the country. many brazilians are unhappy with the right wing present�*s handling of the pandemic which has killed nearly 600,000 people in brazil. those are your headlines here on bbc news. now on bbc news,
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time for click. this week, we're all about genetics. should your dna decide your dinner? how does it shape your personality? and can it be used to track down a murderer? it's the most personal data that you own. it literally defines you. it is your dna. ever since the human genome was decoded, researchers have been peering deeper into what makes us us,
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and more and more companies have been able to build services around what they've found so far. here's what lara has to say on the subject. excuse me. it's not disgusting, it's science. mmm — i think it's both, actually. i look forward to finding out what's got lara spitting feathers later. but first, a story that will make your blood run cold. i'm in iceland, revisiting the freezers at decode genetics in reykjavik, where robots working in temperatures of —26 celsius look after the blood of iceland. over the last quarter of a century icelanders have donated nearly 2 million samples, all in the name of genetic research. if you want to know what —26 celsius feels like, it's very painful on the ears, you really don't feel like breathing very hard at all, and weirdly my nostril hairs are freezing up.
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every time i do that, they're cracking. iceland has been scrupulously recording ancestry records for hundreds of years, so it kind of makes sense that it's also now at the forefront of research to try and identify the specific genes responsible for particular genetic diseases. and what's amazing is the foresight. they gathered a lot of these blood samples before the science became possible to do the things they're now doing. so by gathering it and keeping it for 20 years they can call back, they can go back to be older blood samples, if they have new research techniques available. by doing this they have been able to identify genetic variations associated with many kinds of cancers, and they're now even able
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to estimate how long you have left to live based on levels of particular proteins in your blood. the other fun thing about coming out of this temperature into normal temperature is what happens on cold glass. condensation — lots and lots of condensation. and it doesn't stop forming. so that's it — the camera is written off for about an hour now. and a bit later, once we've dried off and warmed up, i am going to blow your mind with a discovery researchers here have made that links your body shape to the way your mind works. in the meantime, in the us, james clayton has been uncovering a different way in which ancestry data and dna is now being combined to solve murders. the suburbs of fort worth in texas are quiet, sleepy. i'm here to visit the brother of carla walker, a teenager who was abducted and brutally
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murdered in 1974, over four decades ago. i have memories especially of carla sitting out here, talking to girlfriends. she and my sister cindy shared this large room on the second floor. and that's where she lived when she was abducted. that is correct, yeah. her younger brotherjim remembers the day clearly. carla had her pretty dress on, and rodney was looking quite nice in a suit, and we took pictures in front of the fireplace and off they went. we searched for the three days, we searched and searched. hundreds and hundreds of law enforcement, probably near a thousand volunteers were searching everywhere. and i remember a news reporter coming to the house and saying, "mr walker, what are your feelings now that they've found your daughter dead?" that was the first
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we heard about it. carla was severely beaten in the face, brutally raped, and she was choked to death. for over a0 years carla's case remained unsolved, one of an estimated 200,000 cold—case murders in the us — murders that, up until now, we thought would never be solved. we had a lot of really wonderful detectives working on it, trying to move it forward. but, you know, four decades — 44 years before it really got moving again. the breakthrough came not in carla's case but in a case in 2018 on the west coast of america, a stunning investigation that threatens
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to revolutionise cold—case murders across america using ancestry websites. the golden state killer wore a ski mask... the golden state killer was a serial murderer and rapist that terrorised california in the late �*70s and early �*80s. the police had plenty of dna of the killer. however, it didn't match to any dna profiles in the fbi's database. 0ne enterprising officer decided to run the dna found at the murder scenes against dna collected by an ancestry website. these sites are usually designed for people to find genetic relatives through dna links, but the police realised that if they put the killer's dna into the database, they might be able to find the murderer�*s relatives — a crucial clue. most ancestry websites don't allow law enforcement checks, but a few do.
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the website the police chose to use was a company called gedmatch. so effectively what they're doing is building family trees. so you have to build back far enough until you reach what they call a most recent common ancestor, and then figure out where the trees came together, and then build forward from there. so, by doing that, you're able to zero in on who the potential suspect is. the capture of the golden state killer was a proof—of—concept moment — the technique worked. so could it be used to solve carla's case? you want to find hits that are within third cousins to make the case tractable, so we definitely had some that were within third—cousin range. 0thram was founded shortly after the golden state killer was identified, with a mission to solve unsolvable cases. the company's ceo, david mittelman, says the first step in the process is to clean up the dna, which is often degraded. in carla's case, it was
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more than a0 years old. the company then sequences that dna, looking at thousands of distinctive markers on the genome. and in the traditional forensic dna testing framework, like for coders, there's about 20 of these positions in the dna that you're measuring. and that information can be used to confirm that you were at a crime scene or that someone closely related to you as a sibling, parent or child was at a crime scene. that's the extent of what you can do with 20 markers. what we do our 0thram is we look at tens of thousands to hundreds of thousands of markers, and with that information we can detect more distant relationships. every time you test for dna, you lose a bit of the sample in the process. in carla's case, there was little of the killer's dna left. it was likely this was the last roll of the dice. we had to ask ourselves, have we seen enough dna that is of this kind of quality and property to really feel confident that there's a good chance we'll have a positive outcome? otherwise we don't want to do
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it, because when you test dna you're consuming it, and so you're destroying evidence. 0nce they'd sequenced to killer's dna, they ran it through several genealogy websites. from there they created a family tree of the killer, and then began to look for possible suspects — the right age, male, who lived in texas at the time of the murder. they developed a theory that the dna found at the scene belonged to a man called glen mccurley, a man who lived close to carla, a man who had previously been a suspect. i know that he had had to drive up and down the road in front of this house thousands of times, probably had even stopped here. they knew who it was, but they had to do their due diligence as law enforcement to confirm.
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and that's what they did, and about two weeks later i got a phone call — we know exactly who it is, we're going to be arresting him. last month mccurley pleaded guilty to the murder of carla walker. some people, however, simply don't believe that ethically this technique should be used — worried that opening up people's dna to law enforcement, people who are not known criminals, could have worrying consequences. genetics isn'tjust any old tool for law enforcement. it's a particular and a potent tool, because it's not like a phone number that you just change when you get too many spam calls, or even a social security number that you might have reissued if somebody takes yours. it's a technology that's in its infancy. we don't know yet what it will tell us, how well it will tell us things about people. the big criticism of this technology is around consent. so after i get my dna tested, i can go on to gedmatch and i can upload my raw dna
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files to the website. but here is the problem with that. i share dna with my relatives, and critics argue that once i've uploaded my dna and agreed to law enforcement checks, i am by association also opting in my entire extended family. and using my dna the police can link hundreds, perhaps even thousands, of my genetic relatives to a crime, potentially none of whom have consented to be on a database used by the police. i think the thing that people have to make their mind up — you have two competing priorities here. the first priority is, you have an absolute right to privacy. but on the same token you have a competing priority, which is, we have a right to not get murdered and raped. what amount of privacy are you willing to give up versus getting, you know, the increased safety in society? we hear about a serial rape, we hear about serial murders. but less prominent are going to be cases that there might be more controversy about,
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whether it's using it in an immigration context or using it in a less serious crime context. we structure our society with suspicion—based reasons to intrude on people's privacy because we felt as a community that that was the right thing to do — even when it means that occasionally some crimes go unsolved. i think it is incredibly hard to say this. i don't mean to minimise or be dismissive of the claim. but we don't make policies about the civil liberties of our whole society based on the personal feelings of single victims, or the needs of single victims. after the apprehension and arrest was made, i started to feel peace — p—e—a—c—e. you know, i didn't realise for almost 4.5 decades i had
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been geared up for a fight. we're not going to go away. we're going to find you, we're not going away. and thank god that day came. hello, it's time for your weekly tech news round—up. it was the week google claimed it is bing's most popular search term, while appealing against antitrust fines from the european union. youtube is now removing videos containing vaccine misinformation for all currently approved vaccines, not just covid—i9. and california has passed a new law to stop workers being fired if they are not meeting productivity targets set by algorithms. it has had ears for a long time. now it has eyes. it is amazon's new robot, astro. the family—themed robot can be controlled remotely and features a periscope to see in high places. however, some critics have raised privacy concerns. facebook has delayed releasing a version of instagram for children after parents and experts raised safety concerns. this comes as recent research
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has increasingly shown how use of social media can affect the mental health of young people, with many under—135 already using instagram. and finally, as china announces a complete ban on cryptocurrency, one hamster is busy raking in profits from its cage. mr goxx is currently outperforming the s&p 500, with a portfolio up by nearly 24% sincejune. the german rodent�*s crypto—rigged office lets him perform exercises that execute trades. gives a whole new meaning to "wheeling and dealing". we've seen the power dna can have in solving crime and the ethical dilemmas around that, yet many are willing to give up a little saliva to get to know themselves better. dnanudge assesses customers' propensity for certain conditions, guiding them away
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from the foods that would also increase their risk. if you've got the genes for hypertension, then salt is something you should be careful of. if you've got the genes for type 2 diabetes, saturated fat and sugar are your problem. so what we do is we relate those conditions or those genetic risks to those macronutrients in food. time to hand over my dna, which i've been assured will be destroyed straight after it's been analysed. and we load that into the cartridge, and then we load the cartridge into one of the nudge boxes. it looks like a coffee machine. an hour later, i have my results. it looks like i really shouldn't be having salt or much saturated fat. dangerfrom fat medium, calories medium. these aren't actually the results i expected. chris, i'm glad you're to hand. obviously you don't have the obesity risk, but saturated fat and salt
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are indicators much more of cardiovascular, so obviously these are things that you can't see on the surface. my data is then loaded onto a pod that can be worn to help track my exercise and shape my shopping habits. you can scan the foods to see if you can eat them. ok, i shouldn't have that. i can also try it on here, which are also salted peanuts, but it says they're fine to have. 0.39 grams per serving there, 0.6 grams per serving in that, so it's almost double as much salt. i wouldn't have expected that. here you've got the same brand of peanut butter, and just changing from one to the other could apparently save you this much saturated fat over the course of a year — although of course this does all depend on how much you're consuming. so obviously lifestyle does have a big effect on this. what is the percentage balance, then, do you think, between dna and lifestyle? i would say it's roughly 30—70.
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dna is around 30, lifestyle is around 70. dnanudge is not the only company in the dna nutrition and fitness space, and many post kits home. neda gharani tried one after reacting to dairy and bread. once i did the test, i saw that i am actually lactose intolerant, which made sense, and also i am at a slight increased risk for coeliac disease. just that knowledge that there is an increased risk for me really helped me — pushed me to that step of reducing the amount of wheat that i eat. but neda, who is also a research scientist, raised red flags about simplified genetic reports. it's understandable for the general population, but maybe someone who doesn't really understand genetics may take the results as being — having a greater effect than they actually do.
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i took the test myself as well, but the diet recommendations contradicted those of dnanudge. so, a little confused, i took a trip to a nutrition genetics lab. what do you keep in the fridge? it's full of saliva. it is full of saliva. dr yiannis mavrommatis specialises in nutrition genomics here, and instead of offering me a coffee, decided to test my genes as to whether i should have one or not. you can deposit your sample and just return it back to me. it takes longer than you would think to fill a container with saliva. i've only got to get it up to there. done. the problem is not this part, we can do this part quite well. the challenge is to find an area that is meaningful and we have a lot of science behind it. so there is no consensus as to which dna areas we need to analyse, so company a may have their own genes
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that they believe are the most important ones and company b may have a different set of genes. we need to be able to communicate possibilities and probabilities to the public, and that's not always an easy thing to do. even when scientists do agree on genes and their impact, more data is needed for a full picture. genetics can actually be quite meaningful if you combine it with other parameters of the person — their individual dietary inta ke, lifestyle, physical activities, sleep patterns and whatnot. if you just use genetics, it's not going to work. but whilst our dna can't offer every answer, at least dr yiannis later confirmed that i'm free to drink coffee whilst i mull over my need for any diet change — or not. spencer: i tell you, she'd never have given it up anyway. back at decode genetics in iceland, founder kari stefansson has been looking at a similar and possibly controversial topic — how our genes shape our bodies, our minds
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and our personalities. i can tell you how we can use genetics to explore, in a way, the nature of man. his most recent scientific paper has been looking at how that relates to one of the developed world's biggest health problems. if there is one condition that predisposes to more diseases than anything else, it is obesity. 0besity predisposes to heart failure, to liver diseases, to osteoarthritis, to type 2 diabetes. it predisposes to an incredible number of all cancer diseases. now, some people are genetically predisposed to become obese. their genetic make—up means that they'rejust more likely to overeat. not all of these people do become obese, it's just more likely. and, of the people who don't have those genes, well,
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some of those will also become obese for other reasons. so decode set about trying to answer the question: which is it that makes these diseases more likely? is it obesity itself, or is it the genetic tendency for obesity? and it turns out that you are not simply cursed by your genes to get ill. and that genetic tendency has no impact on these diseases, so it is purely the obesity itself that predisposes to the disease. and then we asked the question: what is it, then, that this genetic tendency has an impact on? which part of our biology, which part of our being, is being influenced by this genetic score for obesity? and indeed, we showed that the greater your genetic tendency to become obese is, the worse you perform on all kinds of tests of cognitive function. your verbal iq is less, your performance iq is less, your trail—making test is worse, your education is less. 0besity itself has no impact on cognitive function,
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so you don't become stupid by becoming obese. but the genetic aberration that makes you lose control of eating behaviour has an impact on many other functions of your brain. so obesity makes you susceptible to other diseases regardless of your genes, but the gene which makes obesity more likely does affect your intelligence. the researchers then looked at the data from the other direction and asked: does your personality, and specifically your ability to solve problems, tell you anything about how your physical body might develop? and here they found that the better your visual and spatial ability, the more likely you are to have the genetic tendency for obesity — and all those obesity—related diseases.
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you're also less likely to be curious and creative, but also less likely to suffer from psychiatric conditions like schizophrenia. however, if you score higher on verbal ability, you'll have less risk of obesity and related diseases. you are more likely to be curious and creative, but also you'll have a greater risk of schizophrenia. and what fascinates me about this is that the way in which you are genetically hardwired to solve problems has an impact on the composition of your body. just give me a minute. i'm working it out for myself at the moment. i hope we all are. i know where i am on that, or at least i think i... oh, my god. wow — amazing the secrets that our bodies can hold. and that's it for this week's show. as ever, you can keep up
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with the team throughout the week on social media. find us on youtube, instagram, facebook and twitter @bbcclick, and of course we'll be back next week. thanks for watching, bye—bye. hello. saturday was a soaker where you are. sunday will be a much brighter day. there'll still be showers around, it's still going to be windy, but there will also be some spells of sunshine to be had as well. of course, low pressure responsible for the soaking rain which affected some parts of the uk on saturday. for sunday it's close to northern scotland. this is where we'll start the day with the strongest winds, in the northern isles, especially shetland, gusting 60—70 mph. starting temperatures —
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coldest areas will be across the north of mainland scotland, some spots close to freezing as the day begins. most of the early showers are going to be in western areas. they will travel gradually further east as we go on through the day, and by the afternoon many of the showers are going to be reasonably hit and miss, though a longer spell of rain pushing back across northern scotland and the northern isles. these are average wind speeds. there'll be gusts up to around 35—45 mph. those very strong winds in the northern isles ease a little but it remains very windy here, with gales. and as for temperatures, mostly in the range of around 12 or 13 to 17 degrees celsius. as for the london marathon, it looks like there'll be plenty of sunshine around during the morning. into the afternoon, increasing cloud, and there will be the chance of catching a shower moving through for those who take a little longer, perhaps, to complete the course. now, as we go on into the evening the showers will continue, particularly across western areas. 0vernight and into monday morning there'll be a few more pushing in across south wales and southern parts of england. and as for temperatures, we may just start the day
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on monday a degree or so higher than on sunday morning. and monday will be another day of sunshine and showers. whilst many will be focused across western areas, some again will travel further east during the day. but it's across eastern parts you're most likely to stay dry, with some sunshine. rain gathering to the south—west as monday comes to an end, a bit of uncertainty about how quickly it's wanting to move in. but that's tied in with more weather fronts and another area of low pressure. something to play for in the detail and the position of this going into tuesday, but it's likely to bring another spell of heavy rain and strong winds, particular into wales and england. although maybe some towards the west and the south—west clear up as the day goes on, there'll still be some strong winds and gales around. northern ireland may miss most of it. some of the rain could well push in towards the south and east of scotland. yet more wet and windy weather on the way.
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set by algorithms. this is bbc world news. i'm rich preston. 0ur this is bbc world news. i'm rich preston. our top stories: thousands much for abortion rights across the united states as pro—choice supporters via the supreme court could impose further restrictions.— further restrictions. nobody wakes up — further restrictions. nobody wakes up in _ further restrictions. nobody wakes up in the _ further restrictions. nobody wakes up in the morning . further restrictions. nobody | wakes up in the morning and says, i want to get an abortion today, it is the hardest decision a woman will have to make in her entire life and we should trust women to make that decision for themselves. hundreds forced to evacuate a resort island in honduras is fire destroys dozens of homes. thousands demonstrated across was ill as president —— across presentjair was ill as president —— across present jair bolsonaro's handling of the pandemic. after days of giving at petrol stations, the army will begin delivering fuel across the uk on monday. and this is the live
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