this is bbc news, i'm lewis vaughanjones with the latest headlines for viewers in the uk and around the world... gun shots are heard after a huge fire breaks out at a prison in iran's capital, tehran. state media reports at least eight people injured. as the uk's prime minister fights for herjob — the new chancellor signals he'll make major changes to her economic policy. we have some very difficult decisions ahead, difficult decisions on spending, which is not going to rise as much as people hope and i am going to be asking all government departments to find additional efficiency savings. in northern turkey — at least 41 coal miners have been killed in an underground explosion.

president erdogan promises an investigation. translation: of course we will find out how- this explosion happened, and if there are any people responsible for it with the prosecutions, which have already started. and the husband and wife team behind one of the most successful covid vaccines believe the same technology could help transform cancer treatment. there's been more unrest in iran, including at evin prison in tehran, which houses hundreds of political prisoners and dozens of dual nationals. iranian state media says a fire broke out in the jail after clashes, but that it's

now under control. 8 people were reportedly injured. it follows another day of anti—government protests in several cities. demonstrations began last month in response to the death in custody of a young woman detained for allegedly not wearing her hijab correctly. the bbc�*s, duncan kennedy reports. this is ardabil, north—west of tehran, where protesters have started using rocks to take on the authorities. some are shouting, "death to the supreme leader." a slogan heard a lot in recent weeks. this is also believed to be ardabil, but this time the authorities appear to have the upper hand. the iranian government has brutal control of the media, but using a variety of techniques, the bbc has now named a total of 45 people, including children, who have died since the protests began. many of the demonstrations

are still being driven by young women and schoolchildren. it's nearly a month since these protests began following the death in police custody of a 22—year—old woman. speaking in california yesterday, president biden said the death of mahsa amini has aroused deep feelings in iran. it stunned me, what it awakened in iran. it's awakened something i don't think will be quieted in a long, long time. in another development tonight, shots have been heard in tehran�*s evin prison, after what state media say has been a riot. the jail has been set on fire. hundreds of political prisoners and journalists are held at the prison. duncan kennedy, bbc news. i'm joined now by our reporter azadeh moshiri. let's ta ke let's take a close look at what has been happening today

starting with the events at in the prison what do we know if any more about what his on there? , . , �* there? the picture isn't completely _ there? the picture isn't completely clear - there? the picture isn't completely clear yet i there? the picture isn't| completely clear yet but there? the picture isn't- completely clear yet but what state media is reporting that the fire is under control, no one is killed in that at this point about eight people were injured. authorities also reporting that it was clashes between inmates but separately the fire department is saying they are investigating the cause. so the picture is not clear as well as we are getting reports that there are clashes around the prison and that perhaps the fire is not completely out yet. again none of this is clear yet. what is concerning is when you are looking at a big comp like evin prison engulfed in flames, seeing riot police rushing to the scene traffic around the prison is going to be alarming especially because this is a prison that hold somebody political prisoners, hundreds and dozens of dual nationals. that's why the state department and the us has released a

statement saying that they are holding iran responsible for their wrongfully detained citizens who are in the prison and they hope that no harm will come to them. now of course this is also going to worry a lot of iranians within the country. people rushing to the prison partly that is why they are so much traffic apparently. trying to see that their loved ones are safe. in trying to see that their loved ones are safe.— ones are safe. in the dual nationals _ ones are safe. in the dual nationals in _ ones are safe. in the dual nationals in the _ ones are safe. in the dual nationals in the prison - nationals in the prison increases the likelihood international scrutiny clearly on what is happening, many in the regime will be looking to avoid. we will get more details as we cover them. let's look at the pictures of the protest today on saturday what is your assessment today?— today on saturday what is your assessment today? protests are still widespread. _ assessment today? protests are still widespread. now _ assessment today? protests are still widespread. now more - assessment today? protests are | still widespread. now more than four weeks entering the fifth week of protests that is going to be extremely concerning to the government. there have been these widespread protests like in 2009 or 2019 the last two

big mass protest, they have used a method that has worked every time. combining a brutal crackdown on the people of iran with internet blackouts. that doesn't seem to be working here. that's partly because there are other protests have been about political reforms, electoral issues, fuel prices, so they have not been as widespread in terms of the people involved. here it is led by women in schoolgirls as well, people from all walks of life in all ages. so special when it comes to the internet blackouts, there is such a force behind this movement that these videos are still getting sent to people like other media organisations include yet to limit including bbc persia and using vpns. so the government is not able to quash that global scrutiny as you say. i remember in 2019, the last one and just when the crackdown was getting especially violent there was this deathly silence.

nothing was coming out of the country. that is not happening here. these videos are still coming outjust like this prison but right now. absolutely saturday was was to be an internet blackouts and we are still seeing videos online and there is a great deconstruction on exactly the bbc news is going about verify those videos i do recommend anyone to take a look at that. the key very much. the uk's new finance minister, jeremy hunt, has indicated there'll be major changes to liz truss' entire economic strategy. mr hunt said mistakes had been made by the government and warned of what he called �*very difficult decisions' ahead. he suggested taxes could rise to help restore market confidence and also talked about spending cuts. mr hunt was appointed on friday after the prime minister sacked his predecessor, kwasi kwarteng. here's our political correspondent, ben wright. congratulations, mr chancellor. the fourth chancellor in as many months. jeremy hunt'sjob now is to try and urgently

calm financial markets. he has just two weeks to write a budget that looks set to junk many of the prime minister's signature policies. on wednesday, liz truss said she was absolutely not planning public spending cuts. but listen to this. we have some very difficult decisions ahead, decisions on spending, which is not going to rise as much as people hope, and i'm going to be asking all government departments to find additional efficiency savings. one person's efficiency savings is another person's cuts. yes. during the tory leadership contest, liz truss said the country couldn't tax its way to economic growth, but now... we are also going to have pressure on the tax side. taxes are not going to come down by as much as people hoped, and some taxes will have logo up~ — then there was the prime minister's pledged to boost defence spending to 3% of national income by 2030. but the defence department too is going to have to help find efficiencies. the long—term ability to fund an increase in defence spending

will depend on stability in the economic situation and a healthily growing economy. spending cuts and tax rises is not what liz truss planned when she entered number ten last month but the economic and political turmoil that followed her first chancellor's mini budget has forced a fundamental rethink, plunging her premiership into chaos. yesterday, the smiles had gone and the prime minister's appearance in number ten did little to convince her tory party critics that she is up to the job. some believe herfuture now hinges on the chancellor's budget at the end of this month. if that package doesn't work and the markets are still reacting all over the place, then i think she is in considerable trouble. she has admitted mistakes and if she admits those mistakes and puts them right then i think she could conceivably get beyond this.

but i emphasise could, because i think it all depends on that financial statement on the 31st of october. the opposition said the prime minister's government was now clinging on. they didn'tjust tank the british economy, they also clung on. clung on as they made the pound sink, clung on as they took our pensions to the brink of collapse, clung on as they pushed the mortgages and bills of the british public through the roof. they did all of this. liz truss clearly wants to battle on, hoping this turmoil will subside, but behind her in parliament sits a fractious, even mutinous party. some think it would be mad to try and oust the prime minister already, others say keeping her in place would be worse. rebuilding her political credibility will not be easy. ben wright, bbc news. the governor of the bank of england, andrew bailey, spoke to the new chancellor on friday — and he said there

was a �*clear meeting of minds' on the importance of stability. at the imf in washington, mr bailey also warned of the possibility of higher interest rates ahead — more than previously expected. our business correspondent, marc ashdown, has this analysis. all smiles launching the mini budget at the end of september. and with it a new political phrase — trussonomics, describing liz truss's vision fora high growth, high wage, low tax economy. butjust three weeks later, her new chancellor has buried it. have you been given a clean slate? can you change elements of the mini budget if you want to? yes. and the fundamental thing the prime minister wants me to do and i need to do is to be completely honest with the country. trussonomics reversed, then. tax cuts likely replaced with tax rises, huge investment replaced with a spending slowdown. this rethink has largely been driven by the turmoil

in the financial markets since the mini budget was announced. the pound has had a torrid time. the effective cost of government borrowing has soared and the bank of england had to step in with an emergency programme — buying up government bonds to stabilise the pension sector. there is a pressing need, then, to restore some confidence and credibility. bank of england governor andrew bailey said he spoke to the new chancellor yesterday and had an immediate meeting of minds. but in a speech in washington dc, he had this warning on interest rates. we will not hesitate to raise interest rates to meet the inflation target. and as things stand today, my best guess is that inflationary pressures will require a stronger response than we perhaps thought in august. the current base rate is 2.25%. investors are expecting a rise of up to one percentage point in november to 3.25%. most mortgage offers are currently already around 6%, but a bigger rise in the base rate will affect the economy elsewhere.

and even with a change of approach, the government's problems remain the same — how to find tens of billions of pounds to help people with their energy bills and make the sums add up. we're certainly looking at a really tough couple of years. we've got a very tough economic environment. we've got very stretched public finances. i think we're going to see some even further reversal of the tax cuts that we've had and, in addition, probably some very tight spending rounds. the first verdict will come when financial i don't expect a dramatic reversal, because the devil will be in the detail. and when we find out the detail of the budget on the 31st of october, that will be perhaps a more holisticjudgment being made by financial markets. that's a fortnight away — a long time in the life of a chancellor. marc ashdown, bbc news. to turkey now — and the latest on the explosion in a mine on friday.

earlier, whilst on a visit of the scene of the disaster, president erdogan confirmed that 41 people had died. it's believed a build—up of methane gas caused the explosion at the coal mine in the northern city of amasra on the black sea coast. the bbc�*s, anjana gadgil, reports. a funeral for one of the miners killed in the blast in the black sea costal town of amasra. other families waited outside the morgue where their relatives' bodies lay. it's one of turkey's deadliest industrial accidents in years, and left smoke billowing into the sky. over 100 people were working there at the time. more than 70 workers took part in rescue efforts, which went on throughout the night. crowds gathered around the head of the mineshaft. many were family members of the dead and injured. it's believed methane ignited at a depth of 300 metres, causing a fire in one of the tunnels. president erdogan made a visit

to the scene and said he hoped no more lives would be lost. translation: of course we will find out how- this explosion happened and if there any people are responsible for it with the prosecutions which already started. turkey suffered its deadliest coal mining disaster in 2014, when 301 workers died in a blast in the western town of soma. the local prosecutor's office said it was treating this incident at the state—owned coal mine as an accident and has begun an investigation. anjana gadgil, bbc news. ayla jean yackley, a journalist based in istanbul, told me some of president erdogan�*s comments received a mixed response. he acknowledged that they might be controversial before he uttered them. this is a part of the country that is very much part of his base all along the black sea.

erdogan himself, his family, comes from the black sea and this is a province in turkey that has long supported his government that's been in power since 2002, so it's hard to say at this early stage whether it would have any impact on his support there. and he was referring to this as a matter of faith, that as people of faith, there's belief that fate plays an important role. his critics, however, are pointing out that as there has been in previous disasters after investigations into those, that negligence could play a factor, and one report that is circulating now on social media comes from a 2019 inspection that revealed that there were risks of sudden gas discharges at the depths that these miners were working at, so it's, as i said, very early to say, but there are concerns that there may have been risks that were not taken as seriously as they should have been.

this is bbc news — a reminder of the headlines... gun shots are heard after a huge fire breaks out at a prison in iran's capital — tehran. state media reports at least eight people injured. as the uk's prime minister fights for herjob — the new chancellor signals he'll make major changes to her economic policy. the leader of china, xijinping, is set to be given an historic third term in power, as the communist party congress gets under way in a few hours. and the effort to boost his image and popularity is in full swing across the country. state media has headlined stories about how poorer towns have been transformed after visits from the president. celia hatton, looks at the rise to power of xi jinping. applause.

when he strode onto the stage ten years ago, signalling he'd become china's new leader, he was a relative unknown. he was supposed to rule alongside these six other officials. but now it's clear that he's reshaped the communist party, the military, and the government, so that he's at the top of it all. some call him the chairman of everything. so, how did he do it? how did he become so powerful? he started out with a bold vision — the china dream. it unleashed big projects to build things like high speed rail networks and new global trading routes that aimed to revitalise the whole country. and through viral incidents like this, a visit to a beijing steamed bun shop. he cultivated a different image for himself, making sure everyone in china knew his story and saw him as the top leader. he reorganised the military, too. by ousting hundreds of generals and replacing them with his allies,

he's firmly in control. and let's not forget the ongoing anti—corru ption crackdown. this man, zhou yongkang, is the former top security chief now in prison for amassing $14 billion in ill—gotten gains. more than a million party officials have been punished under xi, silencing all rivals. the campaign's popular with the public, but it's also bred fear. xi is at the top of his game, but he faces serious challenges. china's economy is suffering under tight covid restrictions, and he's made quite a few enemies behind the scenes. china watchers will be looking to see if he begins to delegate any responsibilities, sharing the power and also the blame. celia hatton, bbc news. earlier i spoke to xiaobo lu, professor of political science at barnard college in new york. i began by asking how significant this event is in chinese politics.

it is significant in a number of ways. usually party congress which is held every five years, would decide major policy directions sometimes a new policy directions, sometimes can reiterate existing policies. also every ten years which is this 20th party congress will be at usually, the department leaders would be decided including the very top leader. howeverthis decided including the very top leader. however this time of course, xij—mac is going to have secured his third term. still this round of party officials will be selected at this congress. that is around 100 top and mid—level party

officials. and they are the key executive team of the chinese communist party. they are the ministers, governors, deputy governors. ministers, governors, deputy governm— ministers, governors, deputy covernors. ., . governors. how much power will those people _ governors. how much power will those people have _ governors. how much power will those people have if _ governors. how much power will those people have if the - governors. how much power will those people have if the power l those people have if the power is continually centralised on the man himself?— is continually centralised on the man himself? certainly they are still playing _ the man himself? certainly they are still playing a _ the man himself? certainly they are still playing a key _ the man himself? certainly they are still playing a key role - the man himself? certainly they are still playing a key role in - are still playing a key role in executing the central policies. certainly china is a big country and when the centre has a policy say zero cobit policy. the mid—level officials have their own way of implementing and the lower you go the many different officials will have a hand in executing those policies and the chances of deviating from the policy are great. so there is always that principle agent problems, monitoring the lower, because

the system only has vertical accountability and monitoring without horizontal and that is sometimes policy can be distorted. let's get some of the day's other news. one man has died and two others are missing in greece after torrential rain caused flash flooding on the island of crete. emergency workers say the victim had become trapped in his car. local media are repoting extensive damage in seaside villages, where streets have been inundated with water. residents have been urged to limit their movements. uganda's government has imposed overnight curfews and closed entertainment venues as it tries to stop the spread of ebola. the measures — which will last for three weeks initially, also include the closing of churches and prohibiting movement into and out of the areas affected. 19 people have so far died of the disease

there've been large protests in the tunisian capital against president kais saied — denouncing him as an autocrat who's reversing the democratic progress in the country. mr saied took on full executive power last year but protestors say there's been no improvement in living standards firefighters in the british city of leeds are battling a large blaze in the city centre. the fire broke out on the top floors of a high—rise building earlier on saturday evening, prompting the evacuation of several nearby pubs and restaurants. the husband and wife team behind one of the most successful covid vaccines, say they believe the same technology could help transform cancer treatment. the founders of the german company biontech, added they would fight claims by a rival company, that they infringed patents in their covid jab. our medical editor, fergus walsh reports.

if you have a covid booster this autumn, whether it is the pfizer biontech or moderna jabs, they both rely on a new type of vaccine technology known as mrna. among the pioneers were husband and wife team professors ugur sahin and ozlem tureci. who founded biontech. speaking to sunday with laura kuenssberg the doctor said, mrna is showing promise in cancer studies. where patients receive a personalised vaccine to prompt their immune system to attack their disease. every step, every patient we treat in our cancer trials helps us to find out more about what we are against and how to address that. therefore as scientists, we are always hesitant to say we will have have a cure for cancer. we have a number of breakthroughs and we will

continue to work on them. but it may be several years before we know if trials in bowel cancer, melanoma and other tumour types really do live up to the hype. covid vaccines have been highly successful and made billions for biontech. but rivalfirm moderna has started legal action for patent infringement. in essence claiming key elements of their mrna technology were copied. biontech says it will vigorously defend against the allegations. our innovations are original. we have spent 20 years of research in developing this type of treatment and of course we will fight for our intellectual property. these patent disputes won't stop the roll—out of covid vaccines. mrna technology came of age in the pandemic. the question now is can

it take on cancer? and this is bbc news bye—bye. hello. the weekend started with plenty of showers, some heavy and thundery in places, gusty winds. as one area of low pressure begins to pull away from the uk, there'll be fewer showers around for part two of the weekend. for much of the uk, for much of the day, it'll stay dry. this is that area of low pressure pulling away. however, this is another one moving in towards the southwest later in the day, so there will be some wetter weather pushing north again by sunday evening. let's look at how sunday begins. and still some showers around, especially in scotland, some heavy ones in the west. temperatures a little lower than this in rural parts. a cooler night across southern areas of the uk. the showers in scotland will tend to fade away and they'll still be around the northern isles in the afternoon. but as you can see, though, elsewhere in the afternoon, for most places, it'll be dry, there'll be some sunny spells.

cloud increasing in northern ireland and indeed southern england, south wales, so you could see a few showery bursts of rain heading in later in the afternoon. and by evening, it'll be turning much wetter in northern ireland as this moves north. temperatures pretty much where they're going to be over the next few days, around 12 degrees in glasgow, 18 in london. very wet on sunday evening in northern ireland. we'll see some wet and windy weather pushing north across the uk overnight and into monday morning. the winds picking up again through irish sea and adjacent coasts and into western scotland, with gales in places. a much milder night, especially across wales and england. closer to that area of low pressure on monday, it's northern ireland and northern england that could well see some showers, but it'll be scotland bearing the brunt of some heavy downpours once again. for much of england and wales in the afternoon, actually, it'll be dry, broken cloud and sunny spells and not as windy as it still will be across the northern half of the uk. temperatures on monday

may well be a degree or so higher in places. as we go into tuesday, this latest area of low pressure pulls away. then there's a ridge of high pressure settling things down. there is another area of low pressure, though, sitting to our southwest. and whilst on tuesday, most places are looking dry, just the odd shower here and there, cloud mayjust start to increase across eastern scotland, northeast england. the breeze will pick up later towards the southwest, closer to that next area of low pressure, which will gradually on wednesday start to feed some outbreaks of rain in from the southwest, whereas many places will actually have another dry day. but wetter weather becoming more widespread again towards the end of the week. that's your forecast. bye for now.

this is bbc news. the headlines: a big fire has broken out at evin prison in the iranian capital tehran, where hundreds of political prisoners and dozens of dual nationals are held. in videos posted online, gunfire and sirens can be heard. roads to the prison have been closed off. britain's new chancellor of the exchequer, jeremy hunt, has admitted the government made mistakes when announcing unfunded tax cuts last month and that very difficult economic decisions would now have to be taken. he's promised to restore certainty and predictability to public finances — after weeks of turmoil.