today at 6:00pm, the world is "on the highway to climate hell" — the grim warning from the head of the united nations. as leaders gather in egypt for the latest summit, humanity is told to "cooperate or perish" in the fight to save the future of the planet. the clock is ticking. we are in the fight of our lives and we are losing. the measures to combat climate change agreed last year have seen very little progress, but the uk says the goals are still in place. we remain committed to the 11.6 billion that we announced in the last year for international climate finance, and actually today, we are seeing the benefit that that can bring to countries around the world.

we'll have the latest from justin rowlatt at the summit, where the prime minister rishi sunak hasjust been speaking. also on the programme... five years after the fire at grenfell tower, which claimed 72 lives, the official public inquiry is drawing to a close. many rail services are still badly disrupted despite a series of planned strikes being called off. how fast could you run in your slippers when you were a kid? laughter. and, peter kay announces his long—awaited return to stand—up comedy with his first live tour in 12 years. also this hour on bbc london... protests by climate change activists close parts of the m25 this morning, the same day world leaders gather for cop 27.

good evening. the global climate summit known as cop 27 has started in egypt, with the darkest of warnings from the head of the united nations. antonio guterres said the world was on the "highway to climate hell" with no sign of slowing down, and that humanity needed to "cooperate or perish". he declared that the climate crisis was now the defining issue of our times. last year's climate conference in glasgow agreed a number of pledges on cutting emissions, "phasing down" the use of coal, stopping deforestation, and cutting methane emissions. but the un says progress on cutting emissions has been "woefully inadequate". prime minister rishi sunak has started addressing the summit in the past half an hour and we will have more on that in a second. our climate editorjustin rowlatt is at the summit in egypt and sent this report.

we have had some very wet weather in the uk in the last couple of days, but prepare for worse to come. the environment agency is once again warning of more severe rains this winter as it tries to raise awareness of the risks of floods. and this kind of extreme weather will only become more common as our climate continues to change, it says. in the egyptian desert, world leaders have been gathering to try and tackle the climate challenge. among them, the british prime minister rishi sunak. there was a handshake with the un chief. the 120 orso handshake with the un chief. the 120 or so leaders all got one, part of the launch of what are expected to be some of the most difficult discussions in the three decade history of these climate summits. irate history of these climate summits. we are in history of these climate summits. - are in the fight of our lives and we are in the fight of our lives and we are losing. greenhouse gas emissions keep growing. global temperatures keep growing. global temperatures keep rising. and our planet is fast

approaching tipping points that will make climate chaos irreversible. we are on a highway to climate hell with our foot still on the accelerator.— with our foot still on the accelerator. , ,, ., ~ ., with our foot still on the accelerator. , ,, .,~ ., �* accelerator. rishi sunak, who wasn't auoin to accelerator. rishi sunak, who wasn't going to come _ accelerator. rishi sunak, who wasn't going to come to _ accelerator. rishi sunak, who wasn't going to come to egypt _ accelerator. rishi sunak, who wasn't going to come to egypt to _ accelerator. rishi sunak, who wasn't. going to come to egypt to remember, today stressed how important climate change is to his government. i believe we have found room for hope in glasgow _ believe we have found room for hope in glasgow. with one last chance to create _ in glasgow. with one last chance to create a _ in glasgow. with one last chance to create a plan that would limit global— create a plan that would limit global temperature rises to 1.5 degrees — global temperature rises to 1.5 degrees. we made the promise is to keep that _ degrees. we made the promise is to keep that goal within reach. and the question— keep that goal within reach. and the question today is this, can we summon _ question today is this, can we summon the collective will to detiver— summon the collective will to deliver them? summon the collective will to deliverthem? i believe summon the collective will to deliver them? i believe we can. developing nations are in combative form. i developing nations are in combative form. ., �* ., , ., form. i don't need to repeat the horror and _ form. i don't need to repeat the horror and the _ form. i don't need to repeat the horror and the devastation - form. i don't need to repeat the . horror and the devastation wrecked upon this earth over the course of

the last 12 months. but what we do need to do is understand why, why we are not moving any further. its, need to do is understand why, why we are not moving any further.— are not moving any further. a year of weather — are not moving any further. a year of weather extremes _ are not moving any further. a year of weather extremes around - are not moving any further. a year of weather extremes around the l are not moving any further. a year - of weather extremes around the world underscores that lack of progress. dry weather in the north african country of mauritania caused extensive fires last month. at the glasgow climate conference last year, countries agreed to raise their carbon cutting ambitions every year. butjust 29 out of 193 have done so, and only one of them, australia, significantly raised its game. so where does that leave us? take a look at this. this is how much emissions have been growing. they have been increasing steadily. they have been increasing steadily. the un says we need to cut them almost in half by 2030, so injust seven years' time. but this is the direction the world is currently

going. the un says that puts us on track for a temperature rise of almost three celsius. it would be, it says, a catastrophe for humanity. so what progress can we expect? the countries so what progress can we expect? tie: countries that caused so what progress can we expect? ti2 countries that caused the problem over the last 100 years or so owe something to those who are experiencing now. they would like a financial mechanism agreed here. the developed world isn't really keen on that. so it is pretty ugly in there at the moment. it that. so it is pretty ugly in there at the moment.— at the moment. it sounds like a reci -e at the moment. it sounds like a recipe for _ at the moment. it sounds like a recipe for deadlock. _ at the moment. it sounds like a recipe for deadlock. for - at the moment. it sounds like a recipe for deadlock. for the - at the moment. it sounds like a | recipe for deadlock. for the first time in the history of these conferences there is a dedicated youth zone and the young people are anxious. ., ., , , anxious. nothing new has been said. this is the 27th — anxious. nothing new has been said. this is the 27th of— anxious. nothing new has been said. this is the 27th of its _ anxious. nothing new has been said. this is the 27th of its kind _ anxious. nothing new has been said. this is the 27th of its kind held - this is the 27th of its kind held up it is older— this is the 27th of its kind held up it is older than i am. we this is the 27th of its kind held up it is older than i am.— it is older than i am. we are not 'ust it is older than i am. we are not just here _ it is older than i am. we are not just here as _ it is older than i am. we are not just here as symbols _ it is older than i am. we are not just here as symbols of - it is older than i am. we are not just here as symbols of the - it is older than i am. we are not i just here as symbols of the future. we are _ just here as symbols of the future. we are here — just here as symbols of the future. we are here as— just here as symbols of the future. we are here as representatives - just here as symbols of the future. we are here as representatives ofl we are here as representatives of the climate — we are here as representatives of the climate crisis _ we are here as representatives of the climate crisis being _ we are here as representatives of the climate crisis being lived - the climate crisis being lived through— the climate crisis being lived through us _ the climate crisis being lived through us~ my— the climate crisis being lived through us. my hometown . the climate crisis being lived - through us. my hometown flooded in mexico _ through us. my hometown flooded in mexico that's — through us. my hometown flooded in mexico. that's why— through us. my hometown flooded in mexico. that's why i'm _ through us. my hometown flooded in mexico. that's why i'm a _

through us. my hometown flooded in mexico. that's why i'm a climate - mexico. that's why i'm a climate activist — mexico. that's why i'm a climate activist. ~ ~ , ., ., , ,, activist. we keep having to pressure them. activist. we keep having to pressure them- that's — activist. we keep having to pressure them. that's why _ activist. we keep having to pressure them. that's why we _ activist. we keep having to pressure them. that's why we are _ activist. we keep having to pressure them. that's why we are here - activist. we keep having to pressure them. that's why we are here as - them. that's why we are here as young people, applying that pressure and why will not back down because we believe another world is possible and it is possible to make those policy changes. and it is possible to make those policy changes— and it is possible to make those policy changes. and it is possible to make those oli chances. . ., ., . policy changes. what do you want it? climate justice! _ policy changes. what do you want it? climate justice! young _ policy changes. what do you want it? climate justice! young people - policy changes. what do you want it? climate justice! young people here . climate 'ustice! young people here can't climate justice! young people here can't take part _ climate justice! young people here can't take part in _ climate justice! young people here can't take part in the _ climate justice! young people here can't take part in the formal - can't take part in the formal process. they worry their voice isn't being heard. but no question the youth zone is still the noisiest in the conference. justin rowlatt, bbc news, egypt. the prime minister, rishi sunak, has arrived in egypt following his change of mind about attending the summit, and he addressed the meeting a short while ago. he called for a "global mission for clean growth" — a message echoed by his predecessor boris johnson, who's also attending cop 27, who called on leaders not to weaken their commitment to net zero, which means cutting greenhouse gas emissions to as close to zero as possible. 0ur political editor chris mason is in sharm el—sheikh and sent this report.

dramatic music. this is what international diplomacy looks and sounds like, or at least what the egyptian hosts want us to see and hear. ceremony, serenity, smiles, handshakes. inside, in often cramped meeting rooms, it looks rather more like this. here is the prime minister meeting the president of the european commission this morning. after a room and flag change it was the new prime minister of italy next. and, "oh, the camera's running. look energetic." president emmanuel macron of france. a chance to talk climate, but also try to sort other things out, like those risking their lives crossing the channel in small boats. there is an opportunity for us to work closely, notjust with the french but with other countries as well. you'll hear more details about that in the coming weeks, as those conversations happen amongst all our teams,

but i'm actually leaving this with renewed confidence and optimism that working together with our european partners we can make a difference. is not the honest truth that your home secretary, the person you chose to appoint as home secretary, just six days after she'd resigned from that post, has made the situation worse, made it worse at manston, where plenty of people, according to some, have been held unlawfully? look, the home secretary is actually at the moment making sure that we reduce the numbers at manston and we are making very good progress on that. look who's also turned up, the prime minister before last. what on earth is he doing here? i'm worried that because of what's happening in ukraine, because of the pressure on fuel prices, that people are going soft on the idea of tackling climate change. are you back—seat driving? there was no direct answer, but there was a speech. hey! — slow down, immediately! that's it, game over.

i'm here purely as a foot soldier and spear carrier of the conservative... i'm here in a purely supportive role. borisjohnson has said he is here in a purely supportive role. how would you describe it? it's great that the former prime minister is here. really? i think it says something great about the uk, that not only have we got the current prime minister here, we've got a former prime minister here. itjust demonstrates our leadership on this issue globally. as chancellor during the pandemic we got a sense of rishi sunak�*s priorities, but now he is on the world stage as a leader and we wait to see what his instincts are as prime minister, particularly on foreign affairs. his challenge here, fulfilling expensive promises at a time of a squeeze at home. the new prime minister's flying home tonight. his dash to the egyptian sand done. the colossal scale of his

taskjust beginning. chris mason, bbc news, in sharm el—sheikh. live to sharm el—sheikh and our climate editorjustin rowlatt. we can take stock at the end of this day of talks. progress since last year they say is woefully inadequate. is there any sign there that this year they will lay better foundations? i that this year they will lay better foundations?— that this year they will lay better foundations? ithink, look, ithink glasaow foundations? ithink, look, ithink glasgow did _ foundations? ithink, look, ithink glasgow did lay — foundations? ithink, look, ithink glasgow did lay good _ foundations? ithink, look, ithink| glasgow did lay good foundations. what glasgow called forth, if you like, what is ambition, promises of action. the disappointment here in egypt is that those promises have not been fulfilled. the egyptians say their agenda is implementation. it is getting countries to come good on the promises they have made. glasgow has yet to deliver, if you like, and the question is, can egypt get countries to do that. we have emphasised, this is a huge challenge. there is great anxiety here about whether it will be done.

there are interesting discussions alongside the main speeches today, about how that might happen. there could be a restructuring of the architecture of international finance for example. changes to the way institutions like the imf, the world bank, the world trade organization operates, which may 0rganization operates, which may encourage private capital to come into the battle on climate change. we may not see progress from the governments, but progress may comes from the fringe of the conference. so there may yet be hope here from the sands of egypt, as chris mason put it. the sands of egypt, as chris mason ut it. , , ., ., the sands of egypt, as chris mason ut it. , ., ., ., the sands of egypt, as chris mason utit. , ., ., ., . ., put it. justin rowlatt, our climate editor at the _ put it. justin rowlatt, our climate editor at the cop _ put it. justin rowlatt, our climate editor at the cop 27 _ put it. justin rowlatt, our climate editor at the cop 27 summit, - put it. justin rowlatt, our climate i editor at the cop 27 summit, thank you. there are more details on the issues being discussed at cop 27 — what's happened since cop 26 in glasgow last year, and what households and businesses can do to reduce climate emissions, in a special section on our website — that's at bbc.co.uk/news. most train companies are running

a reduced timetable today despite the fact that three days of strikes by the rmt union have been cancelled. the strikes were called off at the end of last week, but that was apparently too late for many services to be reinstated. let's speak to our transport correspondent katy austin, who's at waterloo station in london. what's the latest on the state of the services? 255 what's the latest on the state of the services?— what's the latest on the state of the services? ~ , , ., ., the services? as you say, on friday when the rmt _ the services? as you say, on friday when the rmt called _ the services? as you say, on friday when the rmt called off— the services? as you say, on friday when the rmt called off the - the services? as you say, on friday when the rmt called off the strikes there was nothing that could be done about saturday. there was a very limited service on saturday. today again passengers have faced a lot of disruption with services starting later than normal and finishing earlier as well, despite train companies trying where they can to put on more services on top of the planned strike day timetable. but it is a very complex operation trying to get a full timetable in place. you have to get enough of the right people and trains in the right places at the right times. that's

very complex. you have to get all the software updated as well. network rail says its signal workers have been working again since saturday so the track is open to run trains if the companies can do so. network rail also says that for some train companies it is a challenge to get drivers and again because their rosters had been drawn up for these strike days. for tomorrow morning, again some services will start later than normal in many areas but we are told things will improve as the day goes on. it should be getting back to normal. and for wednesday, most places will be back to normal again. one more thing to remember on thursday, the planned strike on the london underground and overground is still due to go ahead. fiur london underground and overground is still due to go ahead.— still due to go ahead. our transport correspondent _ still due to go ahead. our transport correspondent at _ still due to go ahead. our transport correspondent at london's - still due to go ahead. our transport| correspondent at london's waterloo station, katy austin, thank you. five years after the fire at grenfell tower in west london, in which 72 people lost their lives, the official public inquiry is drawing to a close this week. today lawyers for the bereaved

families made their closing statements after thousands of hours of evidence and cross—examination, which included debate on fire regulations and the type of cladding used on the building. as our home affairs correspondent tom symonds reports, the conduct of the construction industry, council officials, successive governments and global corporations is under scrutiny. grenfell�*s victims and some of its perpetrators come from all over the world. but this disaster was made in britain. what is striking about the british government's handling of these issues is the startling ignorance of those supposedly in charge. over the years, this inquiry has pieced together the details of what went wrong. today was about the big picture. what is it about modern britain that allowed the grave wrongs of industry to take root, for the emergency response to crash, and for its socially housed population to be treated as objects

and problems rather than people with rights worthy of respect? as it tackled the question of who was to blame for grenfell, the inquiry found companies and organisations blamed each other. another barrister for victims of the fire was not surprised. the very structure of the construction industry was one of buckpassing and the buck was being passed between incompetents. the main aim of each individual organisation was to get the buck off their desk and onto someone else's. stephanie barwise kc named three companies responsible for the use of unsafe materials at grenfell. she said arconic manufactured cladding, knowing it had failed to do well in fire safety tests. studio e, the architects were accused of not being aware of the risks of fire safety. and exova. a fire safety consultant gave advice early in the refurbishment

project that it would not adversely affect safety. she said there had to be major reforms. if the inquiry can affect this sea change it will be a turning point in the industry's long history. the inquiry is under pressure to deliver that. some grenfell families are not confident. they are looking for prosecutions of the companies involved. and... it seems to our clients that what is now required from each of them is an unequivocal, unambiguous and forthright apology. there were also calls for a national memorial day to remember the 72 lives lost in this disaster. tom symonds, bbc news. our top story this evening... a warning from the united nations that the world is "on the highway to climate hell", as world leaders gather in egypt for the latest summit. coming up — red blood cells grown in a lab could revolutionise treatment for some patients.

and coming up in london... researching the impact of long covid. the hospital trying to gain a better understanding to help those suffering. plus the late jamal edwards, honoured for his outstanding contribution to music. hundreds of ukrainian fighters who back in the spring defended a steelworks facility in the city of mariupol, are still being held prisoner by russia. some have been released in prisoner swaps in the meantime. the families of those still being held say they fear for their loved ones. bbc panorama has spent six months tracking down and speaking to those affected — including one woman, hanna, whose husband is still believed to be held. our correspondent hilary andersson has more details, some of her report might upset viewers.

hannah, a 25—year—old french teacher, had it all. just before the war she fell in love and got married and they had a child. but in one day her wild turned to chaos as mariupol became the epicentre of the war. her husband joined up. became the epicentre of the war. her husbandjoined up. hannah became the epicentre of the war. her husband joined up. hannah moved into a bunker in the vast steel plant. her husband based on the other side of the steelworks, fighting.

the steelworks became a living hell with russian firepower raining down. hannah's bunker was hit. but many were injured and died here. finally in late april and evacuation was agreed with civilians trapped in the steel plant and hannah with her baby walking out alive.

her husband was still inside and had been wounded. hannah got a call through to him. when russia won the battle hundreds of ukrainian soldiers surrendered and so did her husband who is still and so did her husband who is still a russian prison. hannah dreams of his return.

hilary anderson, bbc news. the panorama special — mariupol: the people's story — will be on bbc one at 9pm tomorrow night, and a feature—length version will be available on iplayer from 6 o'clock tomorrow morning. the trial of manchester city's benjamin mendy continues today footballer mr mendy, 28, denies seven counts of rape against four women, one count of attempted rape and one count of sexual assault. the offences are alleged to have taken place at his mansion between october 2018 and august last year, and relate to six women. our north of england reporter, rowan bridge, was in court.

benjamin mendy has been on trial for more than two and a half months and today was the first time we heard directly from the french international and manchester city player who spoke english with a heavy french accent and began explaining how he started to get attention from women when he joined the french professional club marseille. he said the intention was ten times more when in 2017 he joined manchester city. he said i know i'm not brad pitt and women did not come to me for what it looked like. he was asked about his attitude to having six with women he did not know until the court at the time i was not thinking about how they were feeling and if they might be upset because if i wanted six and they did everything was fine. he said being placed on remand at manchester prison made him think again and he realised his attitude towards women could be seen as disrespectful. he and his co—accused

deny all the charges against him. benjamin mendy will be back in court tomorrow morning. british scientists are taking part in the world's first clinical trial which has seen red blood cells grown in a laboratory transfused into a human. the manufactured blood cells were grown from stem cells from donors. scientists believe manufactured blood cells could revolutionise treatments for those with blood disorders where it's difficult to find enough donated blood — which is well matched to the patient. our health correspondent catherine burns has the story. every time someone donates blood it can save three lives. but now a clinical trial is try to glow, is trying to grow red blood cells in a laboratory. the

trying to grow red blood cells in a laboratory-— trying to grow red blood cells in a laborato . , ., ., laboratory. the vision at some point is warehouses _ laboratory. the vision at some point is warehouses full _ laboratory. the vision at some point is warehouses full of _ laboratory. the vision at some point is warehouses full of machines - is warehouses full of machines growing blood from stem cells. we are not at that stage yet. for growing blood from stem cells. we are not at that stage yet.— are not at that stage yet. for now it has been — are not at that stage yet. for now it has been tested _ are not at that stage yet. for now it has been tested on _ are not at that stage yet. for now it has been tested on healthy - it has been tested on healthy volunteers. some cells are isolated from donor blood and put into the solution for up to three weeks. the nutrients in this liquid encourage stem cells to multiply and grow into red blood cells. it takes 2a litres to make one or two teaspoons. and scientists also want to see if the laboratory grown cells have some advantages over nature. this donation of blood will contain millions and millions of red blood cells and some will be fresh at the start of the life cycle but others will be older and we are at the end of their life—cycle and researchers hope that the lab grown cells will all be new meaning they could survive in the body for longer. the hope is people who need regular transfusions will not need them so often. like linda ryan who has

sickle—cell, a disorder of the red blood cells. she is alive thanks to monthly blood transfusions but they cause side—effects such as a build—up of iron that could be fatal if left untreated. you build-up of iron that could be fatal if left untreated.— if left untreated. you put it in our if left untreated. you put it in your stomach _ if left untreated. you put it in your stomach and _ if left untreated. you put it in your stomach and it - if left untreated. you put it in your stomach and it runs - if left untreated. you put it in - your stomach and it runs through for ten hours. , ., ~ your stomach and it runs through for ten hours. , . ,, ., , ten hours. three nights a week as she sleeps _ ten hours. three nights a week as she sleeps with _ ten hours. three nights a week as she sleeps with a _ ten hours. three nights a week as she sleeps with a device - ten hours. three nights a week as she sleeps with a device that - ten hours. three nights a week as| she sleeps with a device that helps to break it down. i she sleeps with a device that helps to break it down.— to break it down. i was amazed to hear something _ to break it down. i was amazed to hear something like _ to break it down. i was amazed to hear something like this - to break it down. i was amazed to hear something like this could - to break it down. i was amazed to i hear something like this could even exist in my lifetime. it would make such a difference not having to go every four weeks for a blood transfusion at the hospital. mi transfusion at the hospital. all this comes during a blood shortage in england. this is not a solution to that problem.— to that problem. this will not re - lace to that problem. this will not replace blood _ to that problem. this will not replace blood donors - to that problem. this will not replace blood donors for - to that problem. this will not replace blood donors for the | replace blood donors for the majority of patients, we will always have a need for donated blood but we will be in the future see this being a possibility for patients for whom we currently find it difficult to provide much to provide matched blood. or as a vehicle delivered drugs to patients with rare

diseases. drugs to patients with rare diseases-— drugs to patients with rare diseases. ., , ., ., , diseases. the aim is for the lab crown diseases. the aim is for the lab grown cells _ diseases. the aim is for the lab grown cells to _ diseases. the aim is for the lab grown cells to become - diseases. the aim is for the lab grown cells to become a - diseases. the aim is for the lab - grown cells to become a treatment. this trial is a first step but it could take years to turn into reality. catherine burns, bbc news. one of britain's most popular comedians, peter kay, has announced a return to stand—up comedy with his first live tour in 12 years. he achieved a guinness world record for the biggest—selling run of all time , performing in front of more than a million people. our entertainment correspondent colin paterson reports. peter kay announcing his first stand up for 12 years in a very peter kay way. are you back on tour? next month! his last record—breaking tour was seen by more than a million people. but in 2017 plans to go back on the road were cancelled due to unforeseen family circumstances, right after the tour had sold out. the long wait added to the excitement.

in his home town, bolton fm were dedicating their afternoon show to the news. have you heard the news? what news? peter kay! that lad is comedy gold, let me tell you! he represents everything about families, you know, because his comedyjust reaches across all generations. but also as well i think for everyone in the whole of the country who loves peter kay, because he has not been around for so long, everyone has missed him. and also you know, we need a laugh. and in the town centre it was a major talking point. he just has a genuinely down—to—earth way of making people laugh and that is a talent in itself, isn't it? he's coming back, happy with that. he went to my high school and every assembly you looked for him. it's the classic garlic bread line, isn't it? garlic bread! you are joking!

early in his career peter kay played a landmark show here at bolton's albert halls. of course every venue on this tour is an arena. peter kay has acknowledged the cost of living crisis by putting tickets on sale starting at £35. the same price they were when he last toured. and one place the announcement has caused extra excitement is bolton's carpet shops. if it means i'm getting a ticket, i am doing him a deal! definitely! shh, my boss is in there! colin paterson, bbc news. good luck getting a ticket with that, i will certainly be in the queue. time for a look at the weather. here's louise lear. just take a look at what is

happening down in cornwall as we speak. the wind is strengthening. a storm is coming through the night tonight but it should be short. this plume of cloud moving in and behind thatis plume of cloud moving in and behind that is the cold front. quite a sting in its tail and that is the cold front. quite a sting in its tailand it that is the cold front. quite a sting in its tail and it will bring a spell of wet and windy weather just for a few hours. that is why bearing in mind as we have weather warnings out across parts of south—west england, wales and north west england. you can see that heavy rain and gusts in excess of 65 miles an hour. a lot of rain could bring localised flooding for a time. the good news is it rattles through at quite a pace and by dawn will be out in the north sea and then behind that a trail of showers out to the west. very mild start start tomorrow morning, mild is the story as we go through the second half of the week.

but just take a through the second half of the week. butjust take a case of sunny