this is bbc news broadcasting in the uk and around the globe i'm rebecca jones. our top stories: heartbreak for england fans as a missed penalty sends harry kane's team packing, losing 2—1 to the reigning champions france. the team are now on their way home. meanwhile, morocco becomes the first african and arab country to reach the semi—finals of the football world cup. authorities in jersey say they are no longer looking for survivors after a explosion that destroyed a block of flats yesterday. they have recovered three bodies so far. a teenage girl with seemingly incurable leukaemia — now cancer—free thanks to a revolutionary therapy. we have a special report on the woman ordained

in secret to become a catholic priest — despite the vatican not allowing it. hello and welcome to bbc news. england's footballers are expected to arrive back in the country later today, after their 2—1 world cup quarter—final defeat against france in qatar. the reigning champions will now face morocco for a place in the final. let's speak to our sports reporterjohn watson who's in qatar. most england fans will feel this defeat painfully, because england played well, but they didn't play well enough against a really good

team? it well enough against a really good team? , ., ., well enough against a really good team? , . ., ., ., team? it is the familiar range of emotions. _ team? it is the familiar range of emotions, the _ team? it is the familiar range of emotions, the disappointment, | team? it is the familiar range of. emotions, the disappointment, the frustration the bitterness, but a lot of england fans will be pleased with what they have seen. when england have gone out in the past, there is sometimes a disappointment with the level of performance, sometimes england not seemingly producing their best. but i don't think that was the case last night and the fans showed that, as they stayed on to applaud the players off the pitch, despite harry kane's penalty miss that would have levelled the match late on and who knows what would have come with extra time in the offing. to go toe to toe with the holder france says a lot of the progress they have made. there was for a long time a disconnect between the players and fans, but there has been real signs

of progress. you think about the run to the semi—finals at the last world cup. there was that defeat to italy at the last european championship. there was a sense that perhaps this was going to be the tournament at last where they could produce that big step, that final step. there is a feeling that still perhaps in the big moments, the really big matches, they can't find that extra gear as it played out last night. but something for gareth southgate to reflect on and we wait to see what will he do. he said himself after that defeat, managing a team like england in a major tournament, it takes a lot out of him physically and mentally. he said he will take some time to decide what he is going to do next. a lot of good will and strong feelings from the england fans that they would like to see him carry on in his position and lead the team into the next european championships to come in germany in 18 months�* time. france, we know

about their quality and they showed it again. they�*re hoping to become the first nation to successfully retain the world cup, the first team to do so in 60 years. they fa morocco, who are one of the stories of world cup and they continue to produce upsets and what a performance to get past portugal, knocking out cristiano ronaldo�*s portugal up with nil. for harry kane he said he has accepted responsibility for the miss. he will be disappointed to have missed that penalty that would have levelled last night�*s quarter—final. but they know this squad, with so many young players, the likes of 19—year—old jude bellingham, phil foden, these players that are not shackled by the

disappointments of the past that england fans carry with them, they will draw upon their run to the quarter—finals and the semi—finals of previous world cup and the final appearance at the european championships. they know they�*re knocking on the door in the biggest matches of all. they�*re yet to take that next step, but i think the confidence will be high and they leave here with their heads held high after another impressive showing, albeitjust falling short against france yesterday.- showing, albeitjust falling short against france yesterday. in the last few minutes — we�*ve had news of the audience figures for last night�*s match — and an average audience of 19.1; million tv viewers watched england�*s 1—2 defeat to france on itv.

in their world cup quarter final between 1900 — 2100, according to barb overnights. the five minute peak was 21.31 million for the end of the match. it�*s the most watched single channel tv moment of 2022 so far. let�*s cross to paris and speak to our correspondent hugh schofield. good to talk to you, victory for france, joy for france, yet there were riot police using tear glass in paris last night. tell us what was going on. paris last night. tell us what was auoin on. ., , paris last night. tell us what was auoin on. ., paris last night. tell us what was uuoinon. ., . ., going on. there was riot police on the champs-elysees _ going on. there was riot police on the champs-elysees quite - going on. there was riot police on i the champs-elysees quite regularly, the champs—elysees quite regularly, because they�*re always on the ready in case there are crowds that turn violent. yesterday, there were probably 10, 20,000 people, violent. yesterday, there were probably10, 20,000 people, most violent. yesterday, there were probably 10, 20,000 people, most of it perfectly good tempered, but and this is quite a regular phenomenon in france, there were elements to

decided to take it out on the police and started throwing stones and setting fires. there were 70 or 80 arrests. it sounds a lot, but sadly it is common in france. it mean there is will be a big security presence on wednesday, when morocco/france will be one big game. for all sorts of reasons. of course the semi—final, but the fact there is a moroccan community in france, the history, colonial memories, this will be a tense moment and the security forces will be alive to the potential for trouble.— security forces will be alive to the potential for trouble. what has been the reaction — potential for trouble. what has been the reaction across _ potential for trouble. what has been the reaction across france _ potential for trouble. what has been the reaction across france more - the reaction across france more widely to the match last night and the win? ~ ., ., ,

the win? well, i mean, it goes without saying _ the win? well, i mean, it goes without saying everyone - the win? well, i mean, it goes without saying everyone is - the win? well, i mean, it goes - without saying everyone is delighted and everyone was watching, the figures were 17 million were watching it, it was an exciting match. i think there is a good of respect for the english team and le monde almost implied that england were the better team and that france was lucky to have got away with it, not taking away from the french performance that was in many ways very good as well. there is a feeling that without that failed kick by harry kane towards the end, this could have gone easily the other way. mbappe was an important player, as always, but not the most important player. what is encouraging is this was a game in which he did not sort of solely leave his mark. the goals were scored by others. he was contained up scored by others. he was contained up to a point by the english

defence. and that is encouraging in the sense it shows that it is not just about mbappe and it is a team with plenty of depth as well. good to talk to yom _ with plenty of depth as well. good to talk to you. thank _ with plenty of depth as well. good to talk to you. thank you. - in a world first, a teenage girl�*s incurable cancer has been cleared from her body using of a revolutionary new type of medicine. all other treatments for alyssa�*s leukaemia had failed. the groundbreaking treatment is known as �*base editing�* — it involves making genetic changes to donor cells, enabling them to attack her cancer. 0ur medical editor fergus walsh reports. oh, this one�*s hard. the whole experience has brought me so much closer with my family. alyssa is back home in leicester thanks to a pioneering new cancer therapy. all other treatment options for her leukaemia had failed. breathe in and breathe out. thank you. that's a good one. so, in may, she received a world first therapy.

i know that i�*ve helped other children as well, that other children might be able to get cured because of the research that i�*ve been part in. it is extremely exciting. so, obviously, this is a new field in medicine and it's fascinating that we can redirect the immune system to fight cancer. alyssa�*s immune system couldn�*t clear her cancer, so she was given donor cell, which had been tweaked using a new technique called �*base editing�*. in the lab, three precise changes were made to the cells�* dna and they were then armed to fight her cancer. base editing is part of a genetic revolution which is transforming our understanding of human biology. it is an incredibly precise tool with huge potential to treat and possibly cure a range of diseases, especially disorders of the blood.

ten children with t—cell leukaemia will have the treatment as part of a clinical trial. there�*s enormous amounts of innovation going on in terms of how we can use these new tools to manipulate and change bits of dna and our applications are to cure diseases, and i think there�*s enormous potential to do that across the board. # home—grown alligator. # see you later. # gonna hit the road #. alyssa is still receiving drugs to help herfight infection and she�*ll have regular hospital checks. for now, cancer is undetectable in her blood. to have had this extra year, even to have this last three months where she�*s been well and she�*s been at home and she�*s been doing what she�*s wanted, has been... that�*s like a gift in itself. when you see what she's gone through and the vitality for life that she's brought to every situation is astounding. and she�*s got a lot to look forward to.

christmas, definitely. my auntie's wedding — - i'm going to be her bridesmaid. to go back to school. to hang out with my friends. i want to start riding my bike again, things like that. - look at all these beads. there's loads! every one of these beads represents a procedure alyssa has undergone — a collection she�*s hoping to put away for good. fergus walsh, bbc news. the authorities in the channel island ofjersey say they are no longer looking for survivors after the explosion that destroyed a block of flats on saturday. three bodies have been found so far. there were at least nine known residents at the time of the blast, but authorities say as many as twelve could have been killed, as the number of visitors is not clear. the bbc�*s meghan 0wen reports. candles to mark the lives of those lost, and hope for those still missing. the explosion had funded over

st helier in the early hours of yesterday morning stop emergency services were at the scene within minutes. they found a three story block of flats completely flattened. it is a scene of utter devastation. i mean, the building has completely collapsed. it is, it is that it doesn�*t even look like a building was. smoke stained the skyline of st helier as fire crews helped people from neighbouring buildings. we heard an explosion about four o'clock this morning, 3:30am or4z30am. we got up, we found that in our flat, all the windows had been put in, the staircase had been damaged. and there was fire everywhere. all available emergency vehicles were sent to the scene. throughout the day and into the night, underfloodlights and in freezing conditions, research has continued. local fire crews working alongside specialists flown in from the uk. beyond the rescue, the island has pulled together to help all those affected.

jersey is a very close community, it sounds like a cliche, but it is an island community and everybody knows each other here. the team, i have been on the phone a great deal of time today working with various groups of people both in the community, with the police and clergy and others, just trying to co—ordinate an appropriate and helpful response. this is the second tragedy to hitjersey this week, after a ferry collided with a fishing boat on thursday. three men are presumed dead after their vessel sank. just two weeks before christmas, the island is grieving. let�*s cross to st helier and speak to our reporter meghan 0wen who�*s on the island. this has moved from a rescue to a recovery operation now. what more can you tell us?— can you tell us? well, there is a ress can you tell us? well, there is a press conference _ can you tell us? well, there is a press conference at _ can you tell us? well, there is a press conference at 11 _ can you tell us? well, there is a press conference at 11 in - can you tell us? well, there is a press conference at 11 in the - press conference at 11 in the building behind us, which i understand we will be live streaming. we help to hearfrom the

chief minister and the chiefs of emergency services. so far we know nine known residents lived in the block. we know three bodies have been recoveried. six are being searched for, but there may be additional bodies, as the number of visitors in the block is unknown. it is the news no one wanted to hear. families are getting support and the community are rally together. there are shops opening and and offering warm clothes as the search continues. jerseys is a small island and something like this has shocked the community, to have two incidents like this in the space of a few days is devastating. there will be a lot of questions over what happened yesterday, what made the explosion happen. we know that emergency services were called hours before the explosion happened, due to

reports of the smell of gas. there is an ongoing police investigation. for now the attention is being focussed top bereaved families in the lead up to christmas.- focussed top bereaved families in the lead up to christmas. here in the uk, the health secretary, steve barclay, is being offered the chance to avoid strikes by members of the royal college of nursing in england if he agrees to meet for pay talks. the rcn is due to walk out on the 15th and 20th of december. let�*s speak to our political correspondent helen catt. i think it is worth by starting, please remind us why nurses are going on strike in the first place, because this is unpress depted action. , , , ., ., ., ., action. yes this is not a union that strikes often. _ action. yes this is not a union that strikes often. it _ action. yes this is not a union that strikes often. it is _ action. yes this is not a union that strikes often. it is in _ action. yes this is not a union that strikes often. it is in a _ action. yes this is not a union that strikes often. it is in a dispute - strikes often. it is in a dispute largely about pay. now, nhs staff

this year were given 4.75%. now that varies across, the government said it would mean a newly qualified nurse got 5.5%. but the nurses�* union said they have had many years of below inflation increases and it has left a lot of their members in difficult circumstances. so they are calling for a much bigger rise of 5% over the rpi rate of inflation, which is 14% scotland. sof that that would be a pay rise of 19%. what pat cullen of the rcn has done today is say we will press pause on this action this week if the health secretary will come to the table and talk about pay. this is what she said. ,.,, ., .,, ., talk about pay. this is what she said. ., ., . ., said. our position has not changed, absolutely not, _ said. our position has not changed, absolutely not, but _ said. our position has not changed,

absolutely not, but what _ said. our position has not changed, absolutely not, but what i'm - said. our position has not changed, absolutely not, but what i'm saying | absolutely not, but what i'm saying is the _ absolutely not, but what i'm saying is the health secretary can choose negotiation over picket lines. my door is_ negotiation over picket lines. my door is open. if he doesn't want to speak— door is open. if he doesn't want to speak to _ door is open. if he doesn't want to speak to me — door is open. if he doesn't want to speak to me in a one—to—one, i'm offering _ speak to me in a one—to—one, i'm offering him — speak to me in a one—to—one, i'm offering him conciliation through acas— offering him conciliation through acas and we can start to do that tomorrow— acas and we can start to do that tomorrow morning at whatever time he wants_ tomorrow morning at whatever time he wants to _ tomorrow morning at whatever time he wants to be _ tomorrow morning at whatever time he wants to be available. that is really — wants to be available. that is really important. 30 wants to be available. that is really important.— wants to be available. that is really important. so that was pat cullen calling _ really important. so that was pat cullen calling for _ really important. so that was pat cullen calling for talks. _ really important. so that was pat cullen calling for talks. the - cullen calling for talks. the question is, how likely is the government to agree to talks? at question is, how likely is the government to agree to talks? at the moment it doesn't _ government to agree to talks? at the moment it doesn't sound _ government to agree to talks? at the moment it doesn't sound like - government to agree to talks? at the moment it doesn't sound like that. government to agree to talks? at the moment it doesn't sound like that is l moment it doesn�*t sound like that is the likely. the health secretary has had talks with the rcn about improving conditions for nhs staff, but on pay it doesn�*t look like they�*re going to go there. james cleverley, the foreign secretary, told laura keunssberg why that was. thejob told laura keunssberg why that was. the job of union leaders is to negotiate _ the job of union leaders is to negotiate on _ the job of union leaders is to negotiate on behalf- the job of union leaders is to negotiate on behalf of - the job of union leaders is to negotiate on behalf of their. negotiate on behalf of their members. _ negotiate on behalf of their members, they— negotiate on behalf of their members, they do - negotiate on behalf of their members, they do an - negotiate on behalf of their- members, they do an important job b-s members, they do an important job bus irui— members, they do an important job bus but they— members, they do an important job

bgs but they negotiate _ members, they do an important job bgs but they negotiate with - members, they do an important job bgs but they negotiate with their i bgs but they negotiate with their employers — bgs but they negotiate with their employers and _ bgs but they negotiate with their employers and in _ bgs but they negotiate with their employers and in this _ bgs but they negotiate with their employers and in this instance . bgs but they negotiate with their i employers and in this instance the employer— employers and in this instance the employer is— employers and in this instance the employer is the _ employers and in this instance the employer is the nhs. _ employers and in this instance the employer is the nhs. now, - employers and in this instance the employer is the nhs. now, the... | employer is the nhs. now, the... throughout— employer is the nhs. now, the... throughout my _ employer is the nhs. now, the... throughout my time _ employer is the nhs. now, the... throughout my time in _ employer is the nhs. now, the... throughout my time in politics- employer is the nhs. now, the... throughout my time in politics i. throughout my time in politics i have _ throughout my time in politics i have always _ throughout my time in politics i have always been _ throughout my time in politics i have always been told - throughout my time in politics i have always been told with - throughout my time in politics i. have always been told with things like the _ have always been told with things like the nhs _ have always been told with things like the nhs and _ have always been told with things like the nhs and these _ have always been told with things like the nhs and these kind - have always been told with things like the nhs and these kind of. like the nhs and these kind of things. — like the nhs and these kind of things. people _ like the nhs and these kind of things, people want _ like the nhs and these kind of things, people want to - like the nhs and these kind of things, people want to take i like the nhs and these kind of. things, people want to take the politics— things, people want to take the politics out, _ things, people want to take the politics out, why _ things, people want to take the politics out, why is _ things, people want to take the politics out, why is why- things, people want to take the politics out, why is why we i things, people want to take the | politics out, why is why we have things, people want to take the i politics out, why is why we have the independent — politics out, why is why we have the independent pay— politics out, why is why we have the independent pay review— politics out, why is why we have the independent pay review body. i politics out, why is why we have the independent pay review body. nowl independent pay review body. now people _ independent pay review body. now people want — independent pay review body. now people want to _ independent pay review body. now people want to bring _ independent pay review body. now people want to bring the _ independent pay review body. now people want to bring the politics i people want to bring the politics back people want to bring the politics hack in — people want to bring the politics back in. g . , , ., back in. james cleverley mentioned the independent _ back in. james cleverley mentioned the independent pay _ back in. james cleverley mentioned the independent pay review- back in. james cleverley mentioned the independent pay review body, l the independent pay review body, there are those for a number of areas and they recommend to the government what the pay rise should be. the government say we have accepted their recommendation and we won�*t get involved in talks. labour are saying, hang on, the rcn is putting this offer on the table to stop the action, it is an open goal for the government to do that. labour�*s shadow health secretary wes streeting was pressed on whether or not if labour were in power they would be agreeing to a 19% pay rise.

we would be prepared to talk about pay, we would be prepared to talk about pay. terms — we would be prepared to talk about pay, terms and conditions and the way the _ pay, terms and conditions and the way the pa — pay, terms and conditions and the way the pa rebody works. the staff who are _ way the pa rebody works. the staff who are going on strike feel their backs _ who are going on strike feel their backs are — who are going on strike feel their backs are against the wall. would ou rive backs are against the wall. would you give them — backs are against the wall. would you give them more _ backs are against the wall. would you give them more money. i backs are against the wall. would you give them more money. we i backs are against the wall. would i you give them more money. we would be willin: you give them more money. we would be willing to — you give them more money. we would be willing to talk, _ you give them more money. we would be willing to talk, but _ you give them more money. we would be willing to talk, but i _ you give them more money. we would be willing to talk, but i would - you give them more money. we would be willing to talk, but i would not i be willing to talk, but i would not create _ be willing to talk, but i would not create a — be willing to talk, but i would not create a hostage to fortune to a labour — create a hostage to fortune to a labour government, the worse thing i could _ labour government, the worse thing i could do— labour government, the worse thing i could do is— labour government, the worse thing i could do is make promises i can't keep _ could do is make promises i can't keep when — could do is make promises i can't keep. when i come on programmes and say we _ keep. when i come on programmes and say we are _ keep. when i come on programmes and say we are going to deliver the biggest — say we are going to deliver the biggest expansion of staff in nhs history— biggest expansion of staff in nhs history r— biggest expansion of staff in nhs history r it is because i'm confident of keeping it. i would be prepared — confident of keeping it. i would be prepared to negotiate if we were in government today. and prepared to negotiate if we were in government today.— government today. and in the newspapers — government today. and in the newspapers he _ government today. and in the newspapers he indicated i government today. and in the newspapers he indicated the i government today. and in the i newspapers he indicated the labour party couldn�*t afford that rise and found himself in a clash with the

health union, the doctors�* union, in the newspaper, he is quoted as saying the nhs shouldn�*t be treated like a shrine and he criticised the bma for his response when he said the nhs needed retomorrow. tomorrow —— reform. the nhs needed retomorrow. tomorrow -- reform. . ~ the nhs needed retomorrow. tomorrow -- reform. ., ,, i. now it�*s time to turn to our 100 women series — and the role offered to women in the catholic church. the vatican has never allowed women to be ordained as priests. but the bbc has met one woman who took part in a secret ordination service — despite knowing she faces excommunication. georgina pearce has more. here i am, i am ready. in a church in new mexico, anne trapiano fulfils a long—held dream. i present to you our newly ordained priest! cheering and applause. but it�*s an unofficial ceremony and one that won�*t be recognised by the roman catholic church.

because the institutional church does not allow women to be priests. the teaching is grounded in scripture thatjesus was male and that he chose 12 men to be his apostles. and that those men chose men to be their apostles. that�*s kind of it in a nutshell. over the past 20 years more than 200 women have gone through unofficial ordinations to priesthood, despite the consequences. a woman who is ordained as a priest is automatically, automatically excommunicated. it�*s treated as one of the most serious crimes in the church. what it does mean is we are not able to receive any of the is to receive any of the sacraments, so i can�*t receive communion or confession or sadly i�*m not going to bible to receive a christian burial. groups of women have been lobbying the vatican for

decades to overturn the ban on women priests and while it remains in place more women have been appointed to other senior roles in the church under pope francis. like sister natalie bequah, the first woman to be appointed to a body which advises the pope and the only woman voting rights in the vatican. what i see is very interesting, what pope francis is doing now you know is opening more ways to disconnect leaderedship is doing now you know is opening more ways to disconnect leadership role from ordination. during so many centuries it has been only men have been ordained as priests and there was a statement byjohn paul ii to say, well, this discussion is closed high why in to say, well, this discussion is closed. that's why in the catholic church at the moment, from an official point of view,

it's not an open... ..an open question. when asked about ordaining women as priests in 2016, pope francis said john paul ii�*s declaration would stand. but the women who feel called to priesthood say they will continue to fight for inclusion. the whole of scripture and the whole of the life ofjesus teaches us that god desires love and justice and equality. so by the church teaching, through its actions, excluding women from ordination, it�*s teaching that women are inferior. the church will not be able to fulfil its mission unless women have equal participation. a change anne sees as essential to the future of the church. much more from the 100 women series on our website. you can find all of the films from the series — just take your pick — by logging on to bbc.com/news

or going via the bbc app. in the last few moments a japanese company has launched a spacecraft destined for the moon. the i—space m1 has taken off from cape canaveral in florida, aboard a space x rocket. the japanese start up are hoping to become the first private company to land on the moon. if the mission is successful then the space—craft will deploy two robotic rovers on the lunar surface, as well as a nasa satellite into lunar orbit. a reminder of our top story — england�*s footballers are expected to arrive back in the country later today, after their 2—1 world cup quarter—final defeat against france in qatar. we�*ve heard an average audience of 19.1; million tv viewers in the uk watched the match. the game is the most watched single

channel tv moment of 2022 so far. and you are watching bbc news. hello, parts of the midlands, east wales awoke to the first dusting of snow of the season. for many it was foggy. this is london and big ben there, it was dense in the capital. some of the freezing fog will linger through the day, with ice and further snow showers. the snow showers will continue for northern scotland and some sunshine in between and for northern ireland a few wintry flurries. we have had snow in the central belt and northern england. still some wintriness left and he heavy showers pose annish you for later. —— an

issue for later. some areas could hang below freezing, because of the freezing fog and where we have the snow in the north. the frost becomes more widespread after dark. temperatures down to minus 12 in the snow fields in scotland. minus one or two widely in the towns and cities further south. but the other issueis cities further south. but the other issue is that potential showery weather in the channel turning into something wintry in kent and sussex. but it pushes towards the london region, west to the midlands and up into east anglia and we could in the south and east have the first snow of the season as well. some uncertainty, but it does look as if we will see some around. the freezing fog returns and it will be cold and gloomy tomorrow morning. where the fog lingers, it will stay

gloomy. some sunshine and a scattering of wintry showers in northern scotland. temperatures around the coast three or four, but bitterly cold for most of us. that bitterly cold for most of us. that bitterly cold for most of us. that bitterly cold air stays us with through monday and into tuesday and wednesday. by that stage we will drawn down the arctic wind, which we had last week that brought showers to northern parts of scotland, down the east coast and in the west. but many inland areas had sunshine. a lot of warnings on the web—site.

this is bbc news. the headlines: heartbreak for england fans as a missed penalty sends harry kane�*s team packing, losing 2—1 to the reigning champions, france. the team are now on their way home. meanwhile, morocco becomes the first

african and arab country to reach the semifinals of the football world cup. authorities in jersey say they are no longer looking for survivors after a explosion that destroyed a block of flats yesterday. they have recovered three bodies so far. a teenage girl with seemingly incurable leukaemia is now cancer—free thanks to a revolutionary therapy. now on bbc news, unspun world withjohn simpson. hello and welcome to unspun world, the programme where the bbc�*s experts explain in detail what�*s really going on and where we�*re heading.