good afternoon. the government has said it can't agree to a call by the nursing unions to negotiate with them directly over their 19 % pay claim. the royal college of nursing has offered to pause its planned strikes in england, which are due to begin with a walk—out on thursday, in return for direct negotiations with ministers. the foreign secretary, james cleverly, said the government wanted to resolve the issue but it was for the nhs employers to negotiate with the unions. our political correspondent

helen catt reports. nurses in england, wales and northern ireland are due to walk out twice this month. the strikes will cause disruption as only care for life—threatening cases has to be provided by law. the royal college of nursing says it is prepared to pause the action if the health secretary will agree to talks on pgy- secretary will agree to talks on .a _ , , ., �* secretary will agree to talks on pay. nurses aren't greedy people, they definitely _ pay. nurses aren't greedy people, they definitely are _ pay. nurses aren't greedy people, they definitely are not, _ pay. nurses aren't greedy people, they definitely are not, but - pay. nurses aren't greedy people, they definitely are not, but i - pay. nurses aren't greedy people, they definitely are not, but i knowi they definitely are not, but i know some £27,000 a year living in central london needs to be able to feed her children, be able to send them to school, look after them in creche so they can go to work and pay the trouble to go to work and also pay their utility bills. the government _ also pay their utility bills. the government has _ also pay their utility bills. the government has said it has had talks with the rcn on making the nhs a better place to work, but on pay it won't go there. the better place to work, but on pay it won't go there-— won't go there. the independent review body _ won't go there. the independent review body has _ won't go there. the independent review body has made _ won't go there. the independent review body has made a - review body has made a recommendation the government has accepted _ recommendation the government has accepted fully, and that of course means _ accepted fully, and that of course means there will be a significant increase — means there will be a significant increase in— means there will be a significant increase in pay, particularly for nurses— increase in pay, particularly for nurses at— increase in pay, particularly for nurses at the start of their careers on lower_ nurses at the start of their careers on lower salaries, and we recognise

how tough— on lower salaries, and we recognise how tough it — on lower salaries, and we recognise how tough it is for everybody. medicai— how tough it is for everybody. medical professionals included. we have to _ medical professionals included. we have to make sure we do this in a sustainable — have to make sure we do this in a sustainable way. the have to make sure we do this in a sustainable way.— sustainable way. the average pay rise riven sustainable way. the average pay rise given to _ sustainable way. the average pay rise given to nhs _ sustainable way. the average pay rise given to nhs staff _ sustainable way. the average pay rise given to nhs staff this - sustainable way. the average pay rise given to nhs staff this year. rise given to nhs staff this year was 4.75%, with the lowest paid guaranteed at least £1400. but nurses say years of below inflation pay rises have left them in a difficult position and are calling for a rise of 5% above the rpi rate of inflation, which would currently work out that 19%. labour insist it is the government's fault if the strikes go ahead but wouldn't promise a rise on that scale. i’m promise a rise on that scale. i'm not to make _ promise a rise on that scale. i“n not to make promises i can't keep, blocking things out of thin air, but i would be prepared to negotiate if we were in government today, and i think that's the least we could expect. mr think that's the least we could exect. ~ ,, ., ., , ., think that's the least we could exect. ~ ,, ., ., , expect. mr street and has had his own run-in _ expect. mr street and has had his own run-in with _ expect. mr street and has had his own run-in with a _ expect. mr street and has had his own run-in with a health - expect. mr street and has had his own run-in with a health union, i expect. mr street and has had his i own run-in with a health union, the own run—in with a health union, the bma, which accused him of attacking it in the sunday telegraph this morning. he has claimed the doctor's' union treated him like a heretic for saying there should be better standards for patients. all sides say they don't want the nurses�* walk—outs

sides say they don�*t want the nurses�* walk—outs to go ahead but without the government agreeing to talk about pay they will be on the picket lines come third stay. this is of course just one of many strikes this month as the country faces are significantly disrupted december. helen kat, bbc news. rescuers searching the scene of an explosion injersey in which at least three people died have said they no longer expect to find anyone else alive. specialist teams who spent the night combing the wreckage in st helier, said their mission is now a "recovery operation". there are reports blame — there had been reports the authoriteis . in the last half hour, the news conference has taken place in jersey. it�*s awful, but islanders can have confidence in their emergency services. islanders can have confidence in the states ofjersey fire and rescue service. what assurance will you give those families who will want to know how this happened and if it could have been prevented? i think the answer is in your question, actually, if you don�*t mind. i think that what those families deserve and what those families will absolutely

receive is openness and transparency from me on behalf of my organisation every step of the way. live now to st helier and our reporter meghan 0wen. bring us up—to—date with the very latest. we�*ve had confirmation from the press conference that they are no longer looking for survivors. the meticulous recovery operation is now under way. meticulous recovery operation is now underway. it meticulous recovery operation is now under way. it is now known that nine residents lived in the block of flats. three bodies have been found, six are being searched for, and extra visitors may have been there as well. this is the news that many were dreading here injersey, and families are being supported. it is a very small island and this is a hugely significant major incident. questions will be asked. we know emergency services were called to the block of flats just hours before the block of flats just hours before the explosion happened. there were reports of the smell of gas. we

heard the fire chiefs say that something has clearly gone horribly wrong, and he promised transparency and cooperation. for now, the efforts continue to help bereaved families in the lead up to christmas. thank you. megan 0wen in st helier. a teenage girl has become the first person in the world to be successfully treated for leukaemia using a new type of cell therapy. alyssa, who�*s 13 and from leicester, is now free from cancer. doctors at great 0rmond street hospital in london used cells from a healthy donor which had been genetically modified to attack the girl�*s cancer. england�*s footballers are on their way home after their 2—1 world cup quarter—final defeat against france in qatar. their captain, harry kane, said it had been a tough defeat to take. england�*s manager gareth southgate insisted that there was a lot to be excited for in future, but said he hadn�*t decided whether he will see out the remaining two

years of his contract. our sports editor dan roan reports from doha. 0ut out of the tournament they believed they could win, england�*s dejected players left their hotel earlier than they had hoped this morning. the journey than they had hoped this morning. thejourney home than they had hoped this morning. the journey home accompanied by all—too—familiar thoughts of what might have been. it was never going to be easy. france showing why they are world champions as they took the lead. england are made of more stern stuff these days and when the brazilian referee finally found in their favour, brazilian referee finally found in theirfavour, harry kane brazilian referee finally found in their favour, harry kane took his chance to equalise.— their favour, harry kane took his chance to equalise. kane scores for encland. chance to equalise. kane scores for england- his _ chance to equalise. kane scores for england. his team _ chance to equalise. kane scores for england. his team were _ chance to equalise. kane scores for england. his team were now- chance to equalise. kane scores for england. his team were now on - chance to equalise. kane scores for| england. his team were now on top, but havin: england. his team were now on top, but having gone _ england. his team were now on top, but having gone so _ england. his team were now on top, but having gone so close _ england. his team were now on top, but having gone so close to - england. his team were now on top, but having gone so close to taking . but having gone so close to taking the lead, it was france who did so. giroud�*s deflected header decisive. england needed to dig deep and with time running out this foul on mason mount presented a chance to rescue themselves, or so they thought. this would have put kane clear as

england�*s record goal—scorer and almost certainly take on this epic into extra time, but instead, the cruellest of twists.— into extra time, but instead, the cruellest of twists. he's missed it. i shell-shocked _ cruellest of twists. he's missed it. i shell-shocked england _ cruellest of twists. he's missed it. i shell-shocked england left - cruellest of twists. he's missed it. i shell-shocked england left to - cruellest of twists. he's missed it. | i shell-shocked england left to rue i shell—shocked england left to rue another missed opportunity. we -la ed another missed opportunity. we played well and created chances, we 'ust played well and created chances, we just didn't _ played well and created chances, we just didn't have the lock. the referee — just didn't have the lock. the referee didn't help us. the ball didn'i— referee didn't help us. the ball didn't bounce our way. of course, they— didn't bounce our way. of course, they missed — didn't bounce our way. of course, they missed a penalty from harry, which _ they missed a penalty from harry, which will— they missed a penalty from harry, which will haunt him for the rest of his life. _ which will haunt him for the rest of his life, unfortunately. we can be proud _ his life, unfortunately. we can be proud of — his life, unfortunately. we can be proud of our achievements, itjust wasn't _ proud of our achievements, itjust wasn't to— proud of our achievements, itjust wasn't to he — proud of our achievements, itjust wasn't to be on the night. amid proud of our achievements, it 'ust wasn't to be on the night. amid the ain of wasn't to be on the night. amid the pain of defeat. _ wasn't to be on the night. amid the pain of defeat, england's _ wasn't to be on the night. amid the pain of defeat, england's 56 - wasn't to be on the night. amid the pain of defeat, england's 56 year. pain of defeat, england�*s 56 year long wait for major silverware continues. the manager who has breathed new life into the side now considering his future.— considering his future. these tournaments _ considering his future. these tournaments take _ considering his future. these tournaments take a - considering his future. these tournaments take a lot - considering his future. these tournaments take a lot out i considering his future. these | tournaments take a lot out of considering his future. these - tournaments take a lot out of you and i need time to reflect, and we have done that after every tournament and i believe it is the right thing to do. 50 tournament and i believe it is the right thing to do.— right thing to do. so it is france who will play — right thing to do. so it is france who will play surprise _ right thing to do. so it is france l who will play surprise semifinalist morocco this week as they bid to become the first team for 60 years to retain the title. england are undoubtedly a growing force in the

game but leave town amid a sense of a missed opportunity. that report from our sports editor in doha. cricket, and pakistan have fought back at the second test match against england in multan. after enjoying the best of the first two days, england found life much tougher today. pakistan are still right in contention, needing another 157 runs with six wickets remaining. ben croucher has more. when england play cricket, the game moves... day three, england batting, expect entertainment and runs. belted off the bat of harry brooke, wasting little time to get his second test century, a happy harry for ringwood. there is one at least. the batting pakistan out of this series, that was more problematic. good grab, said ben stokes. he wasn�*t wrong. five wickets before lunch meant the home side were chasing 355 to win — challenge accepted. hold the pose, stand and admire. 0rjust stare in

disbelief as not once, not twice but three times england tickled the timbers, not that pakistan saw the funny side of it. victory could still be theirs after half centuries for a mammal hack and soldier keel. imam�*s patients meant the last laugh today at least was england�*s. you can see more on all of today�*s stories on the bbc news channel. including all the latest on delete my continuing investigation into the explosion that destroyed a building injersey. the next news on bbc one is at 5.55pm. bye for now.

hello.

you�*re watching the bbc news channel. the authorities injersey have confirmed they are no longer looking for survivors from a block of flats explosion that killed at least three people. it is understood there were nine known residents in the block before the blast in st helier on saturday morning. in the past half an hour they have given an update. jersey chief police officer robin smith outlined the recovery situation. it is vitally important we are sensitive to the families�* it is vitally important we are sensitive to the families�* thou-ht sensitive to the families�* thought and emotions as we begin what will be a meticulous and painstaking search of the debris left following the explosion. in terms of the forward look, we have now very

specialist staff not only in states jersey police but also supported by colleagues in the uk to start carefully identifying bodies when and if we find them. that will take time. a teenage girl�*s incurable cancer has been cleared from her body using a revolutionary new type of medicine. all other treatments for alyssa�*s leukaemia had failed. the ground—breaking treatment is known as "�*base editing�* — it involves making genetic changes to donor cells, enabling them to attack her cancer. 0ur medical editor fergus walsh reports. oh, this one�*s hard. the whole experience has brought me so much closer with my family. alyssa is back home in leicester thanks to a pioneering new cancer therapy. all other treatment options for her leukaemia had failed. breathe in and breathe out. thank you. that�*s a good one. so, in may, she received

a world first therapy. i know that i've helped other children as well, that other children might be able to get cured because of the research that i've been part in. it is extremely exciting. so, obviously, this is a new field in medicine and it�*s fascinating that we can redirect the immune system to fight cancer. alyssa�*s immune system couldn�*t clear her cancer, so she was given donor cell, which had been tweaked using a new technique called �*base editing�*. in the lab, three precise changes were made to the cells�* dna and they were then armed to fight her cancer. base editing is part of a genetic revolution which is transforming our understanding of human biology. it is an incredibly precise tool with huge potential to treat

and possibly cure a range of diseases, especially disorders of the blood. ten children with t—cell leukaemia will have the treatment as part of a clinical trial. there�*s enormous amounts of innovation going on in terms of how we can use these new tools to manipulate and change bits of dna and our applications are to cure diseases, and i think there�*s enormous potential to do that across the board. # home—grown alligator. # see you later. # gonna hit the road #. alyssa is still receiving drugs to help herfight infection and she�*ll have regular hospital checks. for now, cancer is undetectable in her blood. to have had this extra year, even to have this last three months where she�*s been well and she�*s been at home and she�*s been doing what she�*s wanted, has been... that�*s like a gift in itself. when you see what she's gone through and the vitality for life that she's brought to every situation is astounding. -

and she�*s got a lot to look forward to. christmas, definitely. my auntie's wedding — i'm going to be her bridesmaid. to go back to school. to hang out with my friends. i want to start riding my bike again, things like that. look at all these beads. there's loads! every one of these beads represents a procedure alyssa has undergone — a collection she�*s hoping to put away for good. fergus walsh, bbc news. as the temperatures in the uk drop, mountain rescue teams are bracing themselves for a busy few months. every day in winter they walk to the top of helvellyn mountain to provide data about the conditions — warnings which many walkers disregard. jonathan swingler reports. the hills are definitely a lot busier and we are seeing a lot more things that make us wince. seeing something on social media does not necessarily give a whole

picture of what it is like to get to that place, what the conditions could be like when they get there and what could happen if it actually goes wrong. every day from now until easter, the fell top assessors head up helvellyn. we�*re not fell top policeman, but we are providing information to give people information to keep them safe on the fells. it is very deceptive as well, when we set off today from the car park, you can see the tops of the hills, you could see there quite clearly, then we come up here and you look around here, the cloud is very low and the summits themselves are all in the clouds. unfortunately, 2021 was a record—breaking year. the mountain rescue teams were called out almost 700 times. i think it�*s going to get worse before it gets better. i think we will have more call—outs before we can get the education message out there completely. approximately 30% of our call—outs

could be avoidable. we are encouraging people to plan theirjourneys ahead. we do see people scrabbling around on steep icy slopes, without grapples and ice axes. there is a steep slope and then a 200—foot cliff at the bottom, and they're just not... that lack of imagination, about what could happen if things went wrong. we see it all the time. you know, i followed a couple along striding edge in full winter conditions and they were injeans and trainers. a day like this is going to be pretty slick, sort of damp atmosphere. even on christmas day, you will find a fell top assessor making the journey up here. they take vital measurements to give us an idea of what to expect. 0n clear days, at over 3000 feet, they can capture some of these stunning views. i�*m notjust going to get my camera out anywhere to take a photo, because i�*m looking down a lot, i know places where i can get my camera out and do that safely without risk of falling off. last christmas was described

as absolutely chaotic by the mountain rescue teams. know when to turn back. the hill will always be here for another day. if you get into conditions you�*re not comfortable with, always turn back. here in the uk, data shows the number of schoolchildren who take up smoking is declining, but new figures suggest there�*s an increase in those who have started vaping. a recent survey carried out across senior schools in yorkshire found about one in five pupils had tried it. health experts in york are now working with children to help them quit, as michelle lyons reports. we are going to work on vaping and talk about the harmfulness of it.

year ten students in york are being told the facts about vaping. it has become a growing trend among young people in recent years who often tryjust to be social, but some become hooked. like 14—year—old lily. when did you start vaping? the end of year 7, was used to my parents with a vape in their hand. i tried it and it got more addictive, it would have been the start of this year, and towards the end of last year, and then ever since then, i've just had it more or less every day. it�*s a growing habit among schoolchildren, which teachers are trying to stop. we�*ve noticed a huge increase in it, especially since coming back from lockdown, we�*ve had students vaping in the toilets, which we�*ve had to deal with. vaping on the school bus, vaping outside the school. they see each other doing it, so it creates a group mentality of, "oh, well, i�*ll try it then."

now health trainers from the city of york council are helping children to quit. we offer about 12 weeks�* worth of one—to—one support. behavioural change, the actual nicotine addiction from that side, then the social and emotional side, the three sides of the triangle, from addiction to smoking or vaping, we support them through that to hopefully get them off that. in this class, a number of students have already tried e—cigarettes. some just out of curiosity, but others are now regular users. i got into it about, maybe the start of year 8, the end of year 7, i tried it and i liked the flavour of it, i bought one and started doing it, and thenjust got addicted to it. i it sort of almost caters to kids, i because you see all the flavours — i couldn't list any of them, j but they are definitely sort of, you can get sweetsl with the same flavours. if i don�*t have one, someone else will, and thatjust

tempts me to have a go on it. do you wish you never started? yes. because i�*ve wasted a lot of money on them. health experts in north yorkshire have noticed that a lot more children are taking up vaping, and that�*s something they�*re concerned about. for people who are existing smokers, actually using an e—cigarette can be really helpful for them, for quitting. for children and young people thinking about taking up e cigarette use, the message is that it is very addictive. nicotine is as addictive as heroin. so in that sense you probably will get hooked quite easily. and as we are not entirely sure about some of the harms yet, it�*s probably not the best thing to be doing. it�*s illegal for anyone under the age of 18 to buy e—cigarettes, but many young people are still getting hold of them. for some, it�*s just a fleeting fad. for others, it�*s become an expensive habit — one they will hopefully be able to kick with the right support.

michelle lyons reporting there. nasa�*s 0rion space capsule is due to return to earth in just a few hours�* time, ending a three week test mission around the moon. the unmanned capsule will splash down in the pacific ocean, off the coast of california. if it goes smoothly, engineers could determine that its ready to take astronauts back to moon later this decade. i�*m joined now by dr megan argo, who is an astro—physicist at the university of central lancashire. good afternoon. remind us first of all, what was the purpose of this mission? to all, what was the purpose of this mission? ., , ., ., mission? to test a load of the new technologies _ mission? to test a load of the new technologies that _ mission? to test a load of the new technologies that have _ mission? to test a load of the new technologies that have been - technologies that have been developed since the 60s and 70s, the last time we sentiments of the moon, you think how much technology has advanced in that time, rocket technology and electronics and computer systems and human safety

systems, a lot of things need to happen before we put humans into rockets and send them the. has it been a success _ rockets and send them the. has it been a success and _ rockets and send them the. has it been a success and what - rockets and send them the. has it been a success and what have - rockets and send them the. has it been a success and what have we | been a success and what have we learned? . . , , been a success and what have we learned? ., ., , , ., been a success and what have we learned? ., , ., , .. ,, been a success and what have we learned? ., , .. ,, learned? that has been a success so far, we learned? that has been a success so far. we can — learned? that has been a success so far. we can say _ learned? that has been a success so far, we can say 100% _ learned? that has been a success so far, we can say 100% until— learned? that has been a success so far, we can say 10096 until it - far, we can say 100% until it completes the final and arguably most risky aspect of the mission, the re—entry and landing. when you send a spacecraft from the moon back to that hits the atmosphere at about 25,000 mph and happily is a speed before you get into the atmosphere because if you don�*t you can burn up on re—entry and your spacecraft disintegrates and that is not good for any humans on board. the spacecraft has systems and it is designed to slow it down as it comes with austria and it is a heat shield to protect the spacecraft which has to protect the spacecraft which has to stand up to temperature is about 3000 celsius which is half the temperature of the steps of the sun and the parties have to open correctly and that has to come down at the slow enough velocity that that land safe in the ocean and although systems will be tested later this afternoon. i although systems will be tested later this afternoon.— although systems will be tested later this afternoon. i have heard it described _ later this afternoon. i have heard it described like _ later this afternoon. i have heard it described like throwing - later this afternoon. i have heard it described like throwing up - later this afternoon. i have heard

it described like throwing up at i it described like throwing up at about 300 yards and hitting a penny. is it really is complicated is that, it sounds terrifying. it is it really is complicated is that, it sounds terrifying.— it sounds terrifying. it is, you have to be — it sounds terrifying. it is, you have to be really _ it sounds terrifying. it is, you have to be really accurate. it| it sounds terrifying. it is, you i have to be really accurate. it is it sounds terrifying. it is, you . have to be really accurate. it is a very small window you have to hit going back from the moon, you travel quite a long way and hitting a very small target is quite a feat but it is a very narrow window because if you hit the atmosphere to sleep, that an are too high and a rocket risks burning up on re—entry, if you come in shell you can skip off the apathy and go back out into space and then you need a lot of fuel to turn around and come back again. unless you have that feel you are lost, you can come back, so you have to hit that really accurate small target on the earths atmosphere to come back safely.— target on the earths atmosphere to come back safely. some people might think we have — come back safely. some people might think we have had _ come back safely. some people might think we have had astronauts - come back safely. some people might think we have had astronauts on - come back safely. some people might think we have had astronauts on the i think we have had astronauts on the moon, what else is there left to learn, isn�*t it mars and beyond that we should be looking at now? there are a lot of — we should be looking at now? there are a lot of unanswered _ we should be looking at now? ii—urr are a lot of unanswered question still about the lunar surface. we have sent people to several areas of the main fabric of samples from those areas. those are really important because they can let us

give an absolute date to the surfaces, the age of the surfaces on the lunar surface, we can do relative ages from the ground and photographs from the air but to do absolute ageing unido samples from the grants are going back and visiting more areas of the men will give us more of that information and help us understand the evolution of the earth moon system over the last four and a happy one years but getting to mars is a whole level of additional difficulty, a minimum six—monthjourney there additional difficulty, a minimum six—month journey there and you would have to be on the surface for something like 18 months and then a six—monthjourney back something like 18 months and then a six—month journey back again so before we dig it out it makes sense to go back to our nearest neighbour and testing systems and test the rocket technology and human habitation systems at our procedures and whether astronauts can survive with each other on those long duration missions in that sort of harsh environment before we then go on and actually send them to mars for real so there is a lot here that his helping us in that process and getting to mars in the longer term. thank you.

now it�*s time to turn to our 100 women series and meet rita moreno. she�*s an actress from puerto rico who�*s won notjust an oscar, but also an emmy, a grammy and a tony award, making her a member of a very exclusive group. perhaps her best known roll was anita in the 1961 film west side story but now, at the age of 90, she�*s speaking out about racial stereotyping and representation in films and on tv. 0ur correspondent nomia iqbal went to meet her. when i could understand what movies were, i wanted to be a movie star. that was the word, not an actress but a movie star. and i still hear that among very young people and i said to them, oh, let me tell you a few things. you went to hollywood during the golden age of cinema. and you were bigger than life.

when i got my contract at mgm studios, which was the studio of my dreams because that was the studio that made all the great musicals and when i met mr louis, can you imagine what that meant to this 15, 16—year—old girl? the men who produced all of those great mgm musicals and they wanted me to sign a contract with them? it was just unbelievable. unbelievable. they did not know what to do with me because my name was rosita dolores alvario. they changed it to rita moreno. what was that like? because these people have your career in their hands. in their hands, i felt like a prisoner in their hands and it really worried me because i was one of those kids that was just afraid to say no to anything. i�*m sure you�*ve lost count of some

of the racist encounters that you had in the industry, notjust being stereotyped, being puerto rican. tell me what that was like. i was always an island girl. and it seemed just fine at first and then it began to occur to me that that would limit me quite a bit because normally, those kinds of people have accents and almost always the makeup was dark and that went all the way up to west side story. any actress that plays anita is compared to you, how do you feel about that? i can�*t tell you how i feel about that. i suppose it is inevitable. i did win some wonderful awards, i won the oscar, of course. and, yes. you were called the pioneer in the community. la pionera.

i think of other people who have come after you who were as famous and notable as you and they are not a lot. it is better but we are seriously underrepresented in the hispanic community which is shocking to me, i�*m very upset about it. there should be more of you. there should be so many more of me and then some. it is still difficult. and it breaks my heart. i not only feel it, but i see in how i am employed and what kind of films, the quality of the films that are offered to me, i am still in that bind. and it is not in any way that i mind playing a hispanic, it is the kind of hispanic. i would�*ve gotten farther,

which is my deepest regret, had it not been for the fact that i�*m hispanic. i would�*ve had a different career. i know it. much more from the 100 women series on our website. you can find all of the films from the series just take your pick by logging on to bbc.com/news or going via the bbc app. this let�*s bring you some breaking news we�*re getting... a libyan man who has been accused of making accused of making the bomb that brought down the plane over lockerbie is in custody. there is according to scottish prosecutors. the usa announced charges against abu agila masud two years ago saying

that he