this is bbc news. the headlines at 4:00pm: a libyan man suspected of making the bomb that destroyed pan am flight 103 over the town of lockerbie in 1988, is in us custody. a nursing union leader says a planned strike by nurses could be called off, if the health secretary negotiates "seriously" over pay. the one day of action that nurses are going to take on thursday hasn't created the 7.2 million people sitting on our waiting lists. the job of union leaders is to negotiate on behalf of their members, they do an incredibly important job, but they negotiate with their employers. in this instance, the employer is the nhs. a teenage girl with seemingly incurable leukaemia — is now cancer—free thanks to a revolutionary therapy.

authorities in jersey say they are no longer looking for survivors after a explosion that destroyed a block of flats yesterday. the us space agency nasa is all set to bring home its orion capsule which will splashdown in the pacific ocean — it could deterime if its ready to take astronauts back to the moon later this decade. the us department ofjustice says a man accused of making the bomb — which destroyed pan am flight 103 over lockerbie — will soon make his first appearance at a federal court in washington dc. the bombing attack in december 1988 killed 270 people. bbc scotland's home affairs correspondent david cowan told us more.

0n the 32nd anniversary of the lockerbie bombing in 2020, the outgoing us general attorney william barr, announced the charges against abu agila masud. the americans said that masud had confessed to making the bomb, which was smuggled onto a plane in malta, then transferred onto another plane in frankfurt and then ultimately transferred onto pan am 103 at heathrow. it took off and then exploded in the skies over lockerbie in scotland, killing everybody on board, all 259 passengers, passengers and crew, and another 11 people on the ground in lockerbie when the wreckage fell into their homes. the americans allege that masud had made the bomb, only one person has ever been convicted of actually carrying out this operation. that was abdelbaset al—megrahi, who was convicted after standing trial to scottish court in the netherlands. he was jailed for life, but released on compassionate grounds by the scottish government in 2009 and died in libya in 2012.

but the americans and the scots always said others were involved. they're saying that masud was one of the people involved in that operation and they've been pursuing him now for a number of years. he was serving a prison sentence, a ten year prison sentence, for for bombing activities against people who were rising up against colonel gaddafi. last month, the american ambassador to libya, richard norland, met senior officials from the governments of national unity in tripoli. that was on november the 8th. then on the 21st of november, masud's family reported that he'd been kidnapped in tripoli by armed men. they suggested that the government of national unity might be planning to extradite him to the united states. there was something of a backlash to that possibility in libya. there were people from the gnu's justice ministry and also from human rights officials were saying that the case shouldn't be over and shouldn't be reopened. libya had accepted responsibility

and paid a huge amount of compensation back in 2003. they were saying effectively it had been dealt with. but the americans and scots, of course, have always felt that it hadn't been finished. and today we've had a statement from the crown 0ffice, the prosecution service in scotland, saying that the families of those killed in the lockerbie bombing have been told that abu agila masud is in us custody. scottish prosecutors and police working with uk governments and us colleagues will continue to pursue this investigation, they say, with the sole aim of bringing those who acted along with abdelbaset al—megrahi tojustice. joining me now is the bbc�*s north america correspondent david willis. what more have us authorities said? a fairly brief statement they released, the usjustice department, it says the united states is taking custody of the alleged pan am flight

103 bomb maker, he is expected to make his initial appearance in the us district court for the district of columbia. that is washington, dc. additional details, including information regarding public a access to the initial appearance they say will be forthcoming. no details of their of how this extradition was arranged, or indeed when this man will be appearing in federal court. although it is possible, of course, that could happen as early as first thing on monday morning. this will come as a considerable relief, because most of the relatives of those who died in that bombing were, of course, americans, it was a flight from london to new york. there has been a constant pressure from those relatives, or representatives of them, over the course of what, nearly 3a years, for these people to

be bought, brought tojustice. the representatives of the relatives have been meeting with representatives from the justice department, state department, fbi and it appears that pressure has, to and it appears that pressure has, to a greater or lesser extent, now paid off. we heard in that previous reports that a couple of years ago the us justice departmentjust like the us justice departmentjust like the us justice departmentjust like the us attorney general at the time announced charges against may, in connection with the lockerbie bombing and it has taken until now. that was based, it is thought, on in an interview that had been conducted with him in libya as long ago as ten years following the fall of the gaddafi regime, a lot of unanswered questions and we may, of course, get a lot more details as this man is brought to court in the next few days of. brought to court in the next few da 5 of. . ~ brought to court in the next few da sof. ., ~ brought to court in the next few da sof. . ~' , brought to court in the next few

dasof. . , . the government has said it can't agree to a call by the nursing unions to negotiate with them directly over their 19% pay claim. the royal college of nusing has offered to pause its planned strikes in england — which are due to begin with a walk—out on thursday, in return for direct negotiations with ministers. the foreign secretary james cleverly said the government wanted to resolve the issue — but it was for the nhs employers to negotiate with the unions. 0ur political correspondent helen catt reports. nurses in england, wales and northern ireland are due to walk out twice this month. the strikes will cause disruption, as only care for life—threatening cases has to be provided by law. the royal college of nursing says it is prepared to pause the action if the health secretary will agree to talks on pay. nurses aren't greedy people, they definitely are not, but a nurse £27,000 a year living in central london needs to be able to feed her children, be able to send them to school, look after them in creches so they can go to work and pay their travel to go to work

and also pay their utility bills. the government has said it has had talks with the rcn on making the nhs a better place to work, but on pay it won't go there. the independent review body has made a recommendation, the government has accepted it fully, and that of course means there will be a significant increase in pay, particularly for nurses at the start of their careers on lower salaries, and we recognise how tough it is for everybody. medical professionals included. we have to make sure we do this in a sustainable way. the average pay rise given to nhs staff this year was 4.75%, with the lowest paid guaranteed at least £1,400. but nurses say years of below inflation pay rises have left them in a difficult position and are calling for a rise of 5% above the rpi rate of inflation, which would currently work out at 19%. labour insist it is the government's fault if the strikes go ahead but wouldn't promise a rise on that scale.

i'm not going to make promises i can't keep, plucking things out of thin air, but i would be prepared to negotiate if we were in government today, and i think that's the least we could expect. mr streeting has had his own run—in with a health union, the bma, which accused him of attacking it in the sunday telegraph this morning. he has claimed the doctor's' union treated him like a heretic for saying there should be better standards for patients. all sides say they don't want the nurses' walk—outs to go ahead but without the government agreeing to talk about pay they will be on the picket lines come thursday. this is of course just one of many strikes this month as the country faces a significantly disrupted december. helen catt, bbc news. ben zaranko, senior research economist at the institute for fiscal studies, says the pay claim lodged by the nurses comes at a time when the nhs budget is incredibly stretched. the first thing is that if you were going to give nurses a 19% pay rise you would have to provide additional funding to the nhs to pay for that.

that would mean, probably, higher taxes at some point, that is the thing the government is resting with, it seems to have been bumped up with, it seems to have been bumped up against the limits it is willing to raise the taxes, that is why it is resisting calls for additional spending. it would also add demand to the economy, nurses being able to spend more, could act as a benchmark to which the private sector employers, their workers, to which the private sector employers, theirworkers, might employers, their workers, might start employers, theirworkers, might start demanding something similar to the nurses. it might add somewhat to inflationary pressures towards the economy. of course a lot will depend on the specific. the main thing is what it would mean for the nhs budget. matthew taylor, chief executive of the nhs confederation joins us now. thank you forjoining us. i don't know if you could hear much of the previous casque,— know if you could hear much of the previous casque, what do you make of his words, previous casque, what do you make of his words. that _ previous casque, what do you make of his words, that this _ previous casque, what do you make of his words, that this is _ previous casque, what do you make of his words, that this is something - his words, that this is something

that could potentially affect inflation further and that this is something that would require the government to go beyond what it has previously been prepared to do, in terms of spending? this previously been prepared to do, in terms of spending?— terms of spending? this is a difficult situation _ terms of spending? this is a difficult situation and - terms of spending? this is a difficult situation and there l terms of spending? this is a | difficult situation and there is terms of spending? this is a - difficult situation and there is no question that any way we can try to avoid industrial action will be a good thing. more importantly its impact on patients. i am slightly mystified by the minister's assertion that it is nhs employers who are the ones who didn't their negotiations. yes, we do the negotiations. yes, we do the negotiations but we do them on the basis of mandate set by government and the government has been clear that at the moment it wants to stick to those pay review body recommendations and there is no more money. as the person from the iss said, were we unilateral laterally to increase the offer, which we can't do any way, to nhs staff, then

that would have to come from the nhs which doesn't have any extra money. in the end it does rest on the government and the trade unions, trying to find a way of getting through this very difficult situation, when we move into next year, there may be circumstances to make it a bit easier, pay review body will report earlier, hopefully inflation will be coming down, we are finally at long last, many years too late going to have a workforce strategy for the nhs, so there are reasons to believe that we can negotiate better next year, but now we need the government and the trade unions to try to find a way of resolving this issue, avoiding disruption. resolving this issue, avoiding disruption-— resolving this issue, avoiding disrution. ~ , ., ~ disruption. why do you think the foreian disruption. why do you think the foreign secretary, _ disruption. why do you think the foreign secretary, senior - disruption. why do you think the | foreign secretary, senior minister james cleverly said this morning that it james cleverly said this morning thatitis james cleverly said this morning that it is not the government's role to negotiate pay? i that it is not the government's role to negotiate pay?— that it is not the government's role to negotiate pay? i can only imagine he is a slightly _ to negotiate pay? i can only imagine he is a slightly confused, _ to negotiate pay? i can only imagine he is a slightly confused, because i he is a slightly confused, because it is the government's responsibility in the sense that my

organisation does represent nhs employers and we do it on the basis of a mandate set by the government and the government has been clear that it wants to stick to the pay review recommendations and there isn't any additional money to pay for staff wages, a large proportion of the nhs�*s budget comes in wages, so when you increase salaries, even by a relatively small amount, that has a very direct impact on the money available for patient care. it is up to the government and it is up to the trade unions to move away from rhetoric, to try to get around the table and see if we can find a way of avoiding this industrial action. it is coming at a time when the nhs is under huge amount of pressure, it is becoming colder, we know that is going to have consequences in terms of more patient getting sick and we are talking about a health service already under immense strain. briefly, labour has said this morning to the bbc that labour would be willing to negotiate, but that they would not commit to increasing spending. what is your response to

that? that spending. what is your response to that? �* ., ., ., ., spending. what is your response to that? ., ., ., ., , that? at the moment negotiation is what we want. _ that? at the moment negotiation is what we want, it _ that? at the moment negotiation is what we want, it is _ that? at the moment negotiation is what we want, it is not _ that? at the moment negotiation is what we want, it is not helpful - that? at the moment negotiation is what we want, it is not helpful for l what we want, it is not helpful for me to comment on which side is right, orwrong, it is me to comment on which side is right, or wrong, it is a me to comment on which side is right, orwrong, it is a huge me to comment on which side is right, or wrong, it is a huge gap, at the moment, between the trade unions and the government. but i sense that it is possible to find a way of getting through these next few months and getting into a more positive conversation next year. but it is going to require both sides to take a step forward and to do that urgently, because these start next week. . ~ urgently, because these start next week. ., ~ , ., ., urgently, because these start next week. ., ~ ., ., , a world first now, a teenage girl's incurable cancer has been cleared from her body using a revolutionary new type of medicine. all other treatments for alyssa's leukaemia had failed. the ground—breaking treatment is known as �*base editing' — it involves making genetic changes to donor cells, enabling them to attack her cancer. 0ur medical editor fergus walsh reports. oh, this one's hard.

ididn't i didn't feel like it wanted to give up, the whole experience brought me so much closer to the my family. alyssa is back home in leicester thanks to a pioneering new cancer therapy. all other treatment options for her leukaemia had failed. breathe in and breathe out. thank you. that's a good one. so, in may, she received a world first therapy. i know that i've helped other children as well, it is extremely exciting, but obviously this is a new field in medicine and it is fascinating that we can redirect the immune system to fight cancer and i think that is a revolution in our fields. alyssa's immune system couldn't clear her cancer, so she was given donor cell, which had been tweaked using a new technique called �*base editing'. in the lab, three precise changes were made to the cells' dna and they were then armed

to fight her cancer. base editing is part of a genetic revolution which is transforming our understanding of human biology. it is an incredibly precise tool with huge potential to treat and possibly cure a range of diseases, especially disorders of the blood. ten children with t—cell leukaemia will have the treatment as part of a clinical trial. it's a very fast moving area of science, — it's a very fast moving area of science, enormous amounts going on in terms _ science, enormous amounts going on in terms of— science, enormous amounts going on in terms of how we can use these new tools to _ in terms of how we can use these new tools to manipulate change bits of dna _ tools to manipulate change bits of dna 0ur— tools to manipulate change bits of dna. 0urapplication tools to manipulate change bits of dna. 0ur application is to cure diseases— dna. 0ur application is to cure diseases and i think there is enormous potential to do that. # home—grown alligator. # see you later. # gonna hit the road #. alyssa is still receiving drugs to help herfight infection and she'll have regular hospital checks. for now, cancer is

undetectable in her blood. last year with the dreaded christmas because we thought this is our last christmas with her and to have had this extra year, even to have these last three months when she has been at home, been well and in doing what she wanted, that has been a gift in itself. ., , , ,., she wanted, that has been a gift in itself. ., , , , ., she wanted, that has been a gift in| itself-— yes, itself. you must be so proud? yes, when ou itself. you must be so proud? yes, when you see _ itself. you must be so proud? yes, when you see what _ itself. you must be so proud? yes, when you see what she _ itself. you must be so proud? yes, when you see what she has - itself. you must be so proud? yes, when you see what she has gone i when you see what she has gone through. — when you see what she has gone through, hervitality for when you see what she has gone through, her vitality for life,... it astounding. it�*s through, her vitality for life, . .. it astounding.— through, her vitality for life, . .. it astounding. it's amazing i have been able to _ it astounding. it's amazing i have been able to have _ it astounding. it's amazing i have been able to have this _ it astounding. it's amazing i have l been able to have this opportunity, i am very thankful for it, it has given me another chance and also, it is going to help other children as well.

look at all these beads. there's loads! every one of these beads represents a procedure alyssa has undergone — a collection she's hoping to put away for good. fergus walsh, bbc news. sport and for a full round—up, from the bbc sport centre, here's sarah mulkerrins. england are on their way home from qatar after they were knocked out of the tournament last night, captain harry kane says that they will be mentally and physically stronger for the next challenge while manager gareth southgate he says he will review and reflect. let's head live to 0lly foster who is in doha for us. i wonder what's reflections the

england team will be thinking about, experiencing today as the hours move on from that initial heartbreak last night? i on from that initial heartbreak last niuht? ~' , night? i think when we spoke in the last hour you _ night? i think when we spoke in the last hour you asked _ night? i think when we spoke in the last hour you asked me _ night? i think when we spoke in the last hour you asked me the - last hour you asked me the atmosphere around the place now from an england perspective, used the word flat. england are actually released one of their in—house videos, and interview gareth southgate gave this morning, before they left their base, he said, flat, they left their base, he said, flat, the players simply feel flat, he didn't name names but he said there were a couple of individuals who felt responsible for their defeat against the french, he said to them this is a collective responsibility, we are a group here but he talked about a 32nd period that can turn your world upside down, they felt they had really controlled the match for a long period. they had really controlled the match fora long period. —— they had really controlled the match for a long period. —— like a 32nd period.

that is the fine margin as to how they lost that match. he has been a judge of six years, another two years on his contract, of course after every major tournaments they do have a debrief and to reflect to see if there is any responsibility, why things went wrong. but i think there is generally positivity coming out of this, but yes, gareth southgate will be one of those who will decide what his next move will be. i will decide what his next move will be. ., ., ., ~' be. i want to make the right decision. — be. i want to make the right decision, but _ whatever that is, for the team, for england. _ whatever that is, for the team, for england. for— whatever that is, for the team, for england, for the fa, whatever that is, for the team, for england, forthe fa, and i have to be england, forthe fa, and i have to he sure _ england, forthe fa, and i have to he sure that — england, forthe fa, and i have to be sure that whatever decision i make _ be sure that whatever decision i make is— be sure that whatever decision i make is the right one and i think it is right— make is the right one and i think it is right to — make is the right one and i think it is right to take a bit of time to do that, _ is right to take a bit of time to do that, because i know, in the past, how rny— that, because i know, in the past, how my feelings have fluctuated in the immediate aftermath of tournaments. we

the immediate aftermath of tournaments.— the immediate aftermath of tournaments. ~ ., ., , tournaments. we will wait on his decision. tournaments. we will wait on his decision- i _ tournaments. we will wait on his decision. i am _ tournaments. we will wait on his decision. i am sure _ tournaments. we will wait on his decision. i am sure you - tournaments. we will wait on his decision. i am sure you can - tournaments. we will wait on his decision. i am sure you can tell l tournaments. we will wait on his i decision. i am sure you can tell the players to take much positives from that result last night, they will feel it for a long time, but for a lot of england fans, i am sure some will still feel hopeful about upcoming tournaments, based on this project, that is building? i can bet you there are _ project, that is building? i can bet you there are some _ project, that is building? i can bet you there are some few— project, that is building? i can bet you there are some few hundred l project, that is building? i can bet. you there are some few hundred fans here in qatar feeling you there are some few hundred fans here in qatarfeeling hopeful enough that they will probably vote a semifinal ticket. we will wonder what they will do with those. that core of players, particularly forward line, when you think gareth southgate last night, hurricane has surely got a couple more major tournaments in him, although he does turn 30 next year —— like harry kane. another world cup in four years' time. you would have thought harry kane form and fitness permitting will still be leading england and will by then be england's leading goal—scorer of all

time. their average age is 26.2, it is a fantastic and very exciting group of players, so plenty of reasons for england to be very positive and this is not an england team kicked out of a tournament that will be lambasted on their arrival home, they are due to land in the next two or three hours.— next two or three hours. great stuff, next two or three hours. great stuff. we _ next two or three hours. great stuff, we will _ next two or three hours. great stuff, we will have _ next two or three hours. great stuff, we will have more - next two or three hours. great stuff, we will have more from | next two or three hours. great. stuff, we will have more from you next two or three hours. great - stuff, we will have more from you at 6:30pm. pakistan have given themselves a fighting chance of winning the second test match against england in multan. after enjoying the best of the first two days, england found life much tougher on sunday with the home side needing another 157 runs to level the series — with 6 wickets still in hand. ben croucher has more. debris, england batting, expect entertainment. belted off the bat, wasting little time to get to the second test century, a happy harry for england? well, there is one at

least. batting pakistan out of the series, that was more problematic. good grab said ben stokes, it wasn't wrong, more followed as england lost the reigning four wickets before lunch, to set the home side 3—55 to win, more than to make days to do it as well, challenge accepted, hold the pose, stand and admire. 0rjust a stare in disbelief has not once, not twice, but three times england tickled the timbers, not that pakistan saw the funny side of it, the last laugh, that could still be there is. their players are both made half centuries to chip away to that target. bowling to 60, to leave this one right in the balance. whoever wants to win it will have to work for it, that is what they call it a test. the manchester derby in the women's super league ended

in a 1—1 draw at the etihad stadium in front of more than a4,000 fans. in an entertaining game, united went ahead just before the half hour mark — with leah galton finding the back of the net. but the hosts got back into the game after the break, with this headerfrom laura coombs levelling things up, which means united have still never beaten their city rivals in the wsl — they stay second and city in fourth. rangers have won the scottish women's premier league cup for the first time, beating record holders hibs 2—0 at tynecastle lizzie arnot�*s spectacular strike from the edge of the area gave rangers the lead in the first half. and substitute kirsty howat secured the win for rangers against the seven—time winners, adding this trophy to the league title they won last season. there are two games in the championship today. it's currently goalless between promotion hopefuls watford and struggling hull city at vicarage road. earlierjohann berg gudmundsson's free kick was the pick of the goals as burnley beat queens park rangers 3—0 at loftus road. the win moves the clarets three points clear of sheffield united at the top of the table.

in rugby union's champions cup three time winners saracens are trailing edinburgh, in pool a. earlier in pool b sale ran in six tries as they thrashed ulster by 39 points to nil at the aj bell stadium. the du preez brothers were stars of the show with daniel and robert each scoring tries. elsewhere munster are currently trailing 15—10 to toulouse. that's all the sport for now. i'll have more for you in the next hour. rescuers searching the scene of an explosion injersey in which at least three people died have said they no longer expect to find anyone else alive. specialist teams who spent the night combing the wreckage, their mission was now a recovery operation. a report that the authorities had been warned of a

gas leak the day before. 0ur correspondent danjohnson, who's in the island, says more details about events prior to the explosion are being confirmed. those reports of a fire service attendance at this block of flats on friday have been confirmed by the authorities here on the island, that residents smelled gas, were concerned, called the emergency services and the fire crew did attend that building at about 8:30pm on friday night. now, they've not given any more detail of exactly what checks took place, what action occurred, but the fire crew left that building, presumably declared it safe. no further action was taken, as far as we know. but then, the next morning at 4:00am, there was this huge explosion which completely destroyed that block of six flats, a three storey block of flats, which was completely reduced to rubble. and that is where the search and rescue operation was concluded overnight. there were frantic efforts yesterday to try to save people, but the rescue teams, some of them brought here to the island from england, search dogs and equipment that's

been brought in to assist with that search, they decided overnight that they weren't going to find anybody else alive, and that's why this has now moved into a recovery phase of the operation. well, there was a press conference given here this morning by the chief fire officer for the island and the island's chief of police. here's what he had to say. it is a time to just think briefly about the families. we have deployed family liaison officers to those families. but it's vitally important that we are sensitive to their thoughts, considerations, emotions, as we now begin what is going to be a meticulous and painstaking search of the debris left following the explosion. so, in terms of the forward look, we have now very specialist staff not only in states ofjersey police, but also supported by this colleagues in the uk, to start carefully identifying bodies when and if we find them.

that will take time. so the authority said there were about a dozen people who are unaccounted for. they've recovered three bodies already. the hope is that the death toll won't reach that high, that those people may be accounted for in other ways. but the fear has got to be that as this search continues, through the rubble, it will be further bodies that are recovered now the chief of police was warning the families of those missing that the chief of police was warning the families of those missing that that recovery and identification work needs to be done carefully, delicately, with dignity and that may mean that it takes perhaps weeks, not days, to actually recover all the bodies from this explosion. on top of that, there is now an investigation into exactly what caused this explosion. the theory, the most likely cause, seems to be a gas explosion of some sort at 4:00am yesterday morning. but then also into the background, what was the nature of that call out on friday night?

what action did the fire service and the gas company here take? could this potentially have been prevented? nasa's 0rion space capsule is due to return to earth in just a few hours' time, ending a three week test mission around the moon. the unmanned capsule will splash down in the pacific ocean — off the coast of california. if it goes smoothly, engineers could determine that its ready to take astronauts back to moon later this decade. 0ur science editor rebecca morelle gave me this update. the spacecraft has been on this long journey around the moon, the really perilous part after the taking of his coming back down to earth. the sacecraft his coming back down to earth. the spacecraft is _ his coming back down to earth. iie: spacecraft is travelling his coming back down to earth. tie: spacecraft is travelling at 25,000 miles an hour, as it enters the earth's atmosphere. as it comes into it it will get incredibly hot, the temperatures will reach 3000 celsius, that is half as hot as the surface of the sun. so really hot.

the spacecraft has to go in exactly the right speed and exactly the right angle to break through the atmosphere. if it doesn't, it might bounce back into space or burn up. both of those are not good things, but once it comes through the atmosphere, it will have slowed down, hopefully, to about 350 mph, thenit down, hopefully, to about 350 mph, then it opens up 11 parachutes, in a different sequence, to splash down in the pacific ocean. so a lot that needs to go right with this, there are no people on board, so it's not quite as risky as if you have astronauts inside, but they want to show that this spacecraft works and it has been a success. we show that this spacecraft works and it has been a success.— it has been a success. we will bring ou it has been a success. we will bring you update — it has been a success. we will bring you update live _ it has been a success. we will bring you update live as _ it has been a success. we will bring you update live as it _ it has been a success. we will bring you update live as it happens. - now it's time for a look at the weather with darren bett. hello there. it's been very cold today. some parts of the country staying below freezing all day. and we've got some icy conditions overnight and into tomorrow, where we've seen those showers. large parts of the country may well become dry during this evening. but our focus shifts towards the south—east, where cloud is thickening, bringing some sleet and snow

into the night in south—east england, east anglia —