kate forbes, the scottish finance secretary. she's just 32, and she's enjoyed a meteoric rise through the ranks. she is currently on maternity leave. angus robertson was for ten years the westminster leader of the snp. he's now a member of nicola sturgeon�*s cabinet. john swinney, a former party leader, now deputy first minister, is the most experienced snp figure after nicola sturgeon. and humza yousaf, who's 37, is the health secretary and a prominent member of the newer generation of snp leaders. our scotland editor, james cook, joins us again. whoever succeeds will have a hard act to follow.

well, they will, because nicola sturgeon will be remembered as one of the most successful politicians of the most successful politicians of her generation in terms of what she delivered at the ballot box, a string of landslide victories for the snp, and if you take a step back to see where she came from, she talked about the 1980s, growing up in ayrshire, and it could have been pretty lonely in those days to campaign for scottish independence when labour was dominant in scottish politics. to go from there all the way to a scottish parliament and to run the government here for eight years is no small achievement, to say the least. but she has always beenin say the least. but she has always been in politics for one thing above all, and she has not delivered to scottish independence, which leaves her successor with big challenges. first of all, immediately on the issue of gender, what to do about westminster blocking the bill that

was passed to try to make it easy to legally change gender, that is contentious. secondly, on the wider issue of independence itself, what do they do, why do they go? is a de facto referendum in the general election a good idea or not? these are big challenges, difficult challenges, and it may be that we will find out in the days, weeks, months and years to come whether this was a high water mark for independence or a waypoint on the route there. it is independence or a waypoint on the route there-— route there. it is a big day, a very significant — route there. it is a big day, a very significant event. _ route there. it is a big day, a very significant event. james, - route there. it is a big day, a very significant event. james, thanks i significant event. james, thanks very much. that's all from the team in edinburgh, in a moment on bbc one we join our colleagues in the nations and regions. good night. from all of us at the scottish

parliament, i wish you a good night. hello i'm hugh ferris. the premier league has new leaders. manchester city won the battle between first and second, 3—1 at arsenal, to replace them at the top of the table. a position the defending champions haven't been in since august. jane dougall reports. the defending champions may be more decorated but manchester city are second in the table to arsenal. it's almost two decades since they won the premier league, so how significant with this match be? whoever was to die, will they win the title to? i whoever was to die, will they win the title to?— the title to? i think we've still not a the title to? i think we've still got a fight — the title to? i think we've still got a fight to _ the title to? i think we've still got a fight to go. _ the title to? i think we've still got a fight to go. tonight it i the title to? i think we've still. got a fight to go. tonight it can the title to? i think we've still- got a fight to go. tonight it can be tiuht. got a fight to go. tonight it can be tight- arsenal _ got a fight to go. tonight it can be tight. arsenal again _ got a fight to go. tonight it can be tight. arsenal again and _ got a fight to go. tonight it can be tight. arsenal again and make - got a fight to go. tonight it can be tight. arsenal again and make it i got a fight to go. tonight it can be | tight. arsenal again and make it by one goat _ tight. arsenal again and make it by one goat |t— tight. arsenal again and make it by one coal. ., , tight. arsenal again and make it by one coal. . , ., tight. arsenal again and make it by oneaoal. , one goal. it was city who struck 1st. one goal. it was city who struck ist- kevin _ one goal. it was city who struck 1st. kevin de _ one goal. it was city who struck 1st. kevin de bruyne _ one goal. it was city who struck 1st. kevin de bruyne pouncing. | one goal. it was city who struck- 1st. kevin de bruyne pouncing. then in error from

1st. kevin de bruyne pouncing. then in errorfrom edelson 1st. kevin de bruyne pouncing. then in error from edelson and arsenal the penalty for the fans desperate for an intervention. but bukayo saka didn't need it. prayers answered. the second saw city take charge. setting up a translate jack grealish. and they are talisman irling harlan made sure of the win. if finished a convincing 3—1 sending manchester city to the top of the read and arsenal questioning their title chances. read and arsenal questioning their title chances. chelsea have still only won once in 2023 after losing the first leg of their champions league last 16 tie at borussia dortmund. despite having a host of chances in germany, chelsea were beaten by karim adeyemi's solo effort on the counter, getting the better of new record signing enzo fernandez as graham potter's side failed to win for the fourth game in a row. the second leg is next month. there was only one english side involved in the champions league tonight, but two english managers. scott parker has been in charge

of club brugge since new year's eve and he's now only one of five englishmen to take charge of a knockout match in the competition. the belgian side lost 2—0 to benfica in their first ever game at this stage of the competition. a penalty and then a late strike from david neres the difference. wales women beat the phillipines in the first match since being paid the same as the men's side. kayleigh green's penalty on the stroke of half—time was enough to give hem a 1—0 win in their opening match in the pinatarcup in spain. scotland have lost their opening match in the pinatar cup 2—0 to iceland. after largely dominating the first half they went behind when debutant 0lof kristinsdottir opened the scoring five minutes into the second half and less than a minute later she fired in a second. scotland's next match is against the phillippines on saturday. england captain leah williamson says

the squad will continue to promote inclusivity ahead of wearing the 0nelove armband at this month's arnold clark cup. it comes after czech republic internationaljakub jankto announced he is gay. england play south korea tomorrow. we are a squad that promotes inclusivity, equality. we obviously have a number of people that feel very strongly about it and i think it is not even a question for us, really. you know, you havejust seen another men's player step out and be as brave as they can be and potentially changed their whole life. they don't know what is coming, so for us to stand also in solidarity with that is important to us. but yeah, it is something we have always done, to something we will continue to do and yeah, like i say, we're notjust impacting football, we are trying to have a positive impact society. meanwhile, manchester united's ella toone, who was sent off against tottenham in the wsl on sunday has had her red card overturned.

tottenham's eveliina summanen has been charged with deceiving a match officialfor her part in the incident and could face a two match ban if found guilty. in the women's t20 world cup india joined england on two wins from two — with a comfortable victory over west indies. batting first, west indies made just 118—6 from their 20 overs, restricted in part by deepti sharma's three wickets. india then reached their target of 119 with 11 balls to spare. wicketkeeper richa ghosh hit the winning runs and top scored with 44 from just 32 deliveries. pakistan batter muneeba ali struck her country's first hundred as they easily beat ireland. the century was the mainstay of their 165 for 5 from their 20 overs. ireland found the chase hard going and were dismissed forjust 95. sadia iqbal took the final wicket but nashra sandhu was the pick of the bowlers finishing with 4—18.

much more on our website. that's all the sport for now. teddy and marla have an nd for the

children are born apparently healthy but the condition gradually attacks the brain and body. this was her when she was two. now eight years later, she can't walk or talk and it is to be fed. later, she can't walk or talk and it is to be fed-— is to be fed. her body is basically araduall is to be fed. her body is basically gradually shutting _ is to be fed. her body is basically gradually shutting down. - is to be fed. her body is basically gradually shutting down. she - is to be fed. her body is basically gradually shutting down. she will lose her eyesight, she will lose most of her senses, basically comes to a point where there is nothing left for her to lose. her to a point where there is nothing left for her to lose.— left for her to lose. her mld had progressed too _ left for her to lose. her mld had progressed too far _ left for her to lose. her mld had progressed too far for _ left for her to lose. her mld had progressed too far for her - left for her to lose. her mld had progressed too far for her to - left for her to lose. her mld had progressed too far for her to be | progressed too far for her to be treated. but it meant the condition was picked up in her sister teddy before damage was done. she's at royal manchester children's hospital having stem cells removed from her blood. the first stage of a ground—breaking gene therapy. ihelium

ground-breaking gene therapy. when the told us ground-breaking gene therapy. when they told us there _ ground-breaking gene therapy. when they told us there was _ ground—breaking gene therapy. when they told us there was treatment available for teddy it felt like a bit of a bitter pill to swallow. natalie can't be helped. we're extremely grateful in 1's sense and really sat on the other. tum extremely grateful in 1's sense and really sat on the other. two months later teddies _ really sat on the other. two months later teddies personalised - really sat on the other. two months later teddies personalised therapy | later teddies personalised therapy is ready. scientists have added a working copy of the gene which causes mld to teddies cells. it cost more than £2.8 million, though the nhs has agreed a confidential discount. this one off in fusion aims to stop teddies disease in its tracks. teddy will need to set the eight spent several more weeks in hospital while her gene altered cells make their way to her bone marrow and start to produce the

crucial missing enzyme that causes her condition. fewer than ten children a year in the uk are likely to be eligible for libmeldi. one reason why the price tag is so high. teddi's doctors are trialling similar treatments for other rare conditions. i think it will be transformative in genetic diseases. libmeldi shows that we can take their own stem cells, put in the gene that their illness is deficient or faulty in, and correct the condition. teddi can expect a healthy future. but nala is terminally ill. her parents want mld screened for at birth, so it's always picked up early enough for treatment. fergus walsh, bbc news.

this is bbc news. we will have the headlines and all the main news stories for you at the top of the hour, straight after this programme.

lara: when 3d printers first went mainstream, many imagined a world where some households would be creating missing pieces of board games or spare parts to fix their cars. the reality has actually probably been more impressive because we're getting 3d—printed houses and even 3d—printed body parts. and some of the latest trials involve printing bones for people who've had cancer. researchers at king's college london and clinicians at guy's and st thomas' nhs foundation trust are collaborating on a project to help cancer patients like colin. i'd quite a few appointments, first of all. i had several tests and a biopsy, which then diagnosed me with cancer. you've got to look at what the alternative is if you don't have it done, isn't it, really? i mean, everybody says that word, �*cancer,’ so you imagine it can

spread here, there and everywhere. in a number of cases of lung, bone or metastatic breast cancer, removing the area around the tumour means the need to take away some of the chest wall. but here, 3d printing is being used to help create something that can replace what's been removed. the way we reconstruct the chest wall is important to preserve the stability of the chest wall and to preserve the way and the breathing mechanic. before 3d printing, there were several different methods. the first one was to use the methyl methacrylate. it's been used by orthopaedics and thoracic surgeons for many years. this cement was modelled at the time of surgery on the patient, just to create a fixed area, like, to replace the ribs or the sternum removed at the time of surgery. then the 3d—printed started and we started to use the titanium. but prosthetics made from titanium are expensive, so this team has developed a novel

way, using 3d printing. this is the 3d—printed model of the prosthesis. i place that into a box and then mix these two parts together. i pour them over this plastic printed part. then once that silicone — like, the liquid silicon cures after about four to six hours, then i remove the printed part and that leaves a cavity in the exact same shape of the patient's anatomy, and that is then sterilised and taken into theatre. in thoracic surgery, when you are removing this area, rather than having three ribs, you are creating, like, a big square of cement. very good to protect your lung... yeah. ..but there was not a good functional result. so, moving from using the same material, you get the same kind of resistance because, you know, you can break it. but also, you have the flexibility, so when you are breathing,

they can move. to me, it was new, putting something foreign in your body. _ but when he explained it to me, it sounded more or less - the right way to go. so, from then on, i had a ct scan, which obviously gave _ all the measurements for them. to make the part, which they did eventually make and it was implanted in me and i've not been _ looking back since. the technology is helping us a lot to provide better surgery with better results for the patients, not only in terms of cancer resection, but also in terms of quality of life and cosmetic results, which, for me, are equally important for my patients. but there's a cost saving as well of nearly £1,000 per procedure, and the whole process is about to get even smarter. by next year, the aim is to directly 3d—print the ribs or sternum. so, instead of a whole process that requires a mould and everything along the way, it'lljust be made straight away in a material like this polymer,

which is called peek, which can be sterilised and then used inside someone's body. i did ask at the time how long this material they use would last, and i was told it would last at least 200 years, which would seen me out here. but then, i never thought of asking at the time how strong that is compared to bone. but apparently, it's as good as bone, so... time will tell! shiona: being here really reminds me of when i was younger and coming for riding lessons, but i've not been on a horse in a very long time. so i'm interested to see how technology is helping people who are learning to ride a horse today. time to get back on the saddle, i guess.

the team here at scotland's rural college have really embraced new tech, and by doing so, it's hoped it can benefit the riders as well as the horses. meet penny who will help me demonstrate. ok, let's go. first up, there are smart reins — they tell me how much pressure i'm putting on penny as she walks. so what we're using here on this horse is a rein pressure sensor. there is a little box that sits on the top of the horse's head and it has two lights that will indicate your left rein and right rein. so if you take any pressure on either rein or both reins, the colour will change. purple indicates low pressure and blue and red show medium and high pressure. they maybe have a problem where they have maybe one rein

a little bit too higher than the other or one a bit shorter than the other, it can really help them to make those adjustments themselves rather than an instructor sort of having to tell them all the time. i have also tried on the biomechanic jacket, which helps me get my posture right, and makes it more comfortable for penny too. initially, we look for a straight line from the shoulder through the hip down to the rider's heel when they're on the horse. we also look for a nice straight line from a relaxed shoulder and then a line from the rider's elbow through the hand, and right down through the rein to the horse's bit. anything different than that, you can restrict the way the horse is going and it can make it quite uncomfortable for the horse and sort of stops them from travelling forward. and so, how are you monitoring that using these fluorescent lines? so what we do is we use a robot camera. it tracks the rider no matter where they go in the arena, and then they can review their riding position afterwards, discuss it with their instructor and then they can see maybe what is really good and what needs improving. and finally, we have the pressure mat.

this mat sits underneath the horse's saddle. we can use it to help learn about saddle fitting initially, but also, it is great for detecting any abnormalities in position, and that pressure mat will pick that up and then it transmits data to an ipad. these four bits of tech being used together mean students here are getting the most modern way of learning in an industry which has been steeped in tradition. and it looks like the college has their eyes on more tech for the future too. got a question for you. would you like to eat and drink on a moving ride? no — why would anybody do that? good question. well, there's a new ride that's opened at one of europe's largest theme parks, and who do we call on when there's a ride involved? ah, lj rich. exactly — so get ready for eatrenalin. how do you stop this thing?

lj: when i was asked to try out a new theme park dining experience called eatrenalin, i wondered what could possibly be in store. well, i wasn't expecting this. turns out it's less a physical thrill ride and more an emotional and culinary experience. the food is augmented by visuals, lighting and music. meals with feels. i've kind of forgotten that i'm moving, but... ..i've still got this sense of...tranquillity. the story behind eatrenalin follows an ai who just wants to become human, while diners are leisurely transported through themed spaces. earlier in the day, i met

co—founder thomas mack for a behind—the—scenes tour of the ride — or is that experience? so, welcome. here are our floating chairs. it's like they are breathing, they are being charged up. is it rollers or is it a cushion of air? so, the first idea was a cushion of air, but then it was too loud, so that was prototype number one. now it is all electrically driven. you have three different wheels, but also, the wheels we developed, the floating chair can move. the chairs use infrared sensors so they don't bump into anything, and run to a preprogrammed journey through the rooms. here, with this sort of movable chair, you're in complete control of your guests' journey. diners change formations throughout the two—hour experience, so each new course brings a new companion, which may or may not add to the enjoyment.

the main event, though, is the food, which is typical of a high—end restaurant. i love going in the kitchens, because this is where all the real work's getting done. and this is amazing. you don't normally get this number of screens in a restaurant kitchen, but in fact it's telling people everything they need to know about the diners�* food tolerances and even exactly where they are sitting whilst they are having the experience. do you come here often? it's my first time. at nearly 200 euros per person, eatrenalin is definitely priced as a high—end restaurant rather than a ride. europa—park aims to sell the concept to other parks and cities around the world, and it's hoping the experience will be attractive to those outside the amusement park industry. it's a bold ambition, and for a company used to exporting

roller—coaster hardware, it is a very big move into uncharted territory. still not convinced — i think that would give me indigestion. nah, i thought it looked great. i'll take someone else then. fine. that's it for the shortcut of click for this week. the full—length version is waiting for you right now on iplayer. thanks for watching. we'll see you soon. bye— bye. hello there. we've had quite a mixed day of weather, really on wednesday. many of us saw some spells of sunshine, but we also had this band of rain, a very narrow weather front that's worked its way

eastwards across scotland, england and wales through the day with the clear and sunny skies either side of that. we ended the day, though, in northern ireland with some thicker high cloud working in creating this halo around the sun. well, that high cloud is associated with the next weather system, bringing damp weather, then, through wednesday night. and into thursday, we'll still have some outbreaks of rain left over, particularly across parts of england and wales, although some patches of drizzle further north for parts of southern and central scotland and northern ireland too. now with that there'll probably be some mist and fog patches around western coast and hills, but gradually through the day the weather will try to brighten up. the best of the sunshine likely to be across northern areas of scotland. that's where the coolest air is. temperatures about eight in stornoway, but otherwise it's another very mild day, 10 to 1a degrees pretty widely across the uk. now for thursday night, we're going to start to see the winds really pick up in strength, particularly across western scotland as a band of rain works

its way southwards here. the rain also affecting northern ireland through the night. england and wales, well, a lot of cloud around, i think. now looking at the weather picture into friday, this area of low pressure moving just to the north of the uk is going to be bringing a zone of strong winds in association with this occlusion. now those strong winds are going to be going straight across scotland where i think through the day we could get gusts as strong as 75 miles an hour and it will also be very windy indeed across the pennines and to the east of the high ground, north—east england down to about yorkshire. now, the winds this strong have the potential to bring some disruption. now the roads could be affected. for example, the a1, those winds would be blowing across the road and that would mean that high—sided vehicles would be at risk, could even see one or two getting blown over. and a similar story around some of the airports. leeds, bradford, for example, crosswinds here may make for some pretty tricky landing conditions. you might find some cancellations or delays to flights, certainly worth checking before heading out and about, but it stays mild. temperatures around 10 to 1a degrees, england and wales. still with some cloud and drizzle around brighter skies, working into northern ireland

and scotland through the afternoon, but still very blustery. now the weekend sees much lighter winds around, but we've still got the remnants of weather fronts slowly pushing southwards before we see a build of pressure into the second half of the weekend. what does all that mean? well, for saturday, probably quite a cloudy day for many areas with the threat of some rain, most of it would be quite light and patchy. and there could be some areas that miss it altogether, perhaps across northern and eastern areas of scotland. temperatures, well, quite a range, mild for many, but a little bit cooler than recent days in scotland. now, sunday for many looks to be the drier of the two days of the weekend. again, cloud will vary, but there should be some sunny spells coming through at times and our temperatures, well, still above the february averages nine in glasgow to about 12 degrees in london. the forecast remains quite reliable up until tuesday. and so for scotland and northern ireland, probably staying cloudy

still with the threat of outbreaks of rain but still mild, the temperatures generally into double figures. further south across england and wales, we're closer to an area of high pressure and that should mean generally, although there's still quite a bit of cloud around, you've got a better chance of seeing some bright or sunny spells, but in the short term, watching out for those strong winds to come through on friday.

welcome to newsday, reporting live from singapore, i'm karishma vaswani. the headlines. republican — nikki haley — launches her campaign to be the next american president — taking on herformer boss — donald trump. for a strong america, for a proud america, i am running for president of the united states of america. applause. scotland's first minister nicola sturgeon resigns after more than eight years in the role — saying it's what's best for herself, her party and for scotland's independence movement. the 19—year—old gunman who killed 10 people at a grocery store in buffalo, new york, is sentenced to life in prison — without parole. and us actress raquel welch, often credited with paving the way