it isa it is a good question, but i today? it is a good question, but i chose to make _ today? it is a good question, but i chose to make one _ today? it is a good question, but i chose to make one episode - today? it is a good question, but i chose to make one episode out i today? it is a good question, but i chose to make one episode out of| today? it is a good question, but i i chose to make one episode out of six about party gait. what happened last year with all the other things that were going on, the war in europe, the end of cobit, the cost of living crisis on set, they really impacted people's lives. 99% of the coverage was about party gait and it has become a national obsession and people can't let it go. the rest are desperate to talk about anything else, the things that really affect their lives. i else, the things that really affect their lives. ., ., ., their lives. i wonder if the ongoing inabili of their lives. i wonder if the ongoing inability of number _ their lives. i wonder if the ongoing inability of number ten _ their lives. i wonder if the ongoing inability of number ten to - their lives. i wonder if the ongoing inability of number ten to focus . their lives. i wonder if the ongoing inability of number ten to focus on i inability of number ten to focus on the business of government, which you have raised, is perhaps because you have raised, is perhaps because you are constantly firefighting crisis about the prime minister's capacity to tell the truth. i crisis about the prime minister's capacity to tell the truth.- capacity to tell the truth. i was not there _ capacity to tell the truth. i was not there when _ capacity to tell the truth. i was not there when these - capacity to tell the truth. i was not there when these events i capacity to tell the truth. i was i not there when these events took place, i was not there when the prime minister said what he did to the house of commons. he followed

uuidance. the house of commons. he followed guidance- yes- _ the house of commons. he followed guidance. yes. i— the house of commons. he followed guidance. yes. ijoined _ the house of commons. he followed guidance. yes. ijoined when - the house of commons. he followed guidance. yes. i joined when thingsl guidance. yes. i “oined when things are re guidance. yes. ijoined when things are pretty traumatic _ guidance. yes. ijoined when things are pretty traumatic and _ guidance. yes. ijoined when things are pretty traumatic and people i guidance. yes. i joined when things i are pretty traumatic and people were traumatised. the government was preoccupied with incoming attacks all the time and throughout this there was war in europe, the cost of living crisis, a massive debate about economic policy, so i am trying to do now is to invite people to think about those things because it is important we get them right. people are able to think about more than one thing at the same time. literally pa rtygate than one thing at the same time. literally partygate took up so much airtime and so much energy and it was almost impossible to get people interested, and the press interested, and the press interested, in what we could do now to avoid the next cost of living crisis, what we could do now to avoid people dying unnecessarily of cancer and heart disease. back avoid people dying unnecessarily of cancer and heart disease.— cancer and heart disease. back in march 2016, — cancer and heart disease. back in march 2016, you _ cancer and heart disease. back in march 2016, you try _ cancer and heart disease. back in march 2016, you try to _ cancer and heart disease. back in march 2016, you try to persuade | march 2016, you try to persuade borisjohnson on the phone not to submit his i am going to go for

brexit, i am going to submit the article to the daily telegraph. he had written a remaining article and a brexit article and was weighing up which want to submit. how much did he not believe in brexit? it is which want to submit. how much did he not believe in brexit?— he not believe in brexit? it is a really tough — he not believe in brexit? it is a really tough question. - he not believe in brexit? it is a really tough question. i - he not believe in brexit? it is a really tough question. i was i really tough question. i was astonished, i had known him for decades and had worked in the office next to his for four years, i thought he was culturally european, he speaks a languages, which not many people do in this country, and he had grown up in brussels. i thought he was as culturally and is intellectually pro—european as it is possible to be in the conservative party. i was astonished. i tried my very best, the reporters were already outside his house, he said he was still weighing up the odd, but you are at and confirmed it. all i can say is whatever doubts he had, he did then persuade himself there was a massive, exciting opportunity for britain to be unleashed, unshackled if you like. what about

how he saw _ unshackled if you like. what about how he saw it _ unshackled if you like. what about how he saw it as _ unshackled if you like. what about how he saw it as affecting - unshackled if you like. what about how he saw it as affecting his i how he saw it as affecting his career? he didn't see a downside? i thought boris was going to be prime minister one day anyway and so what brexit did was take him on a short cut, but a short cut that sowed the seeds of his ultimate demise because, to get back to your first question, he feels there are people in the establishment, whether it is the media, the city, the civil service, who will never forgive him for brexit because they thought it was a disastrous decision for the united kingdom. iwas was a disastrous decision for the united kingdom. i was remain, was a disastrous decision for the united kingdom. iwas remain, as was a disastrous decision for the united kingdom. i was remain, as you say and i think it is a bad decision and i have always thought so, but we have taken that decision and we are stuck with it and we have got to make it work. we stuck with it and we have got to make it work.— stuck with it and we have got to make it work. we are out of time, thank you — make it work. we are out of time, thank you very _ make it work. we are out of time, thank you very much _ make it work. we are out of time, thank you very much for _ make it work. we are out of time, thank you very much for coming . make it work. we are out of time, | thank you very much for coming on the programme. that's all from us tonight. remember you can get in touch at newsnight@bbc.co.uk. i'm back tomorrow. till then enjoy the rest of your evening. goodnight.

this is bbc news. the police recovery vehicle arrived and lifted up recovery vehicle arrived and lifted up and it was then taken away, moved in westminster and everything very much back to normal now this evening. scientists have used artificial intelligence to develop a new antibiotic that can kill a deadly superbug. the ai helped narrow down thousands of potential drugs to a handful that could be tested in the laboratory. nicky schiller explains. recently, we've read about

artificial intelligence when it comes to things like chat bots and creating essays for you. this takes ai creating essays for you. this takes al to a whole creating essays for you. this takes alto a whole different creating essays for you. this takes al to a whole different level. identifying a new antibiotic that can kill one of the worlds most deadliest superbugs. how did the team of researchers in the united states and canada do it? they focused this bacteria, the colour public enemy number one. it is resistant to nearly every known antibiotic in the world. another clever part, they had to train the artificial intelligence. they did by feeding it a list of compounds that they knew could slow down or kill they knew could slow down or kill the superbug. that then created a list of 6680 compounds that they did not know whether it would work or not. look at this. the artificial intelligence to just 90 minutes to come up with a short list. and then 240 were tested in the lab. that then produced nine potential antibiotics. in particular, when thatis antibiotics. in particular, when that is very potent in the test they

killed the superbug and associated infections in mice. doctorjonathan stokes is one of the team behind it and they were two clinical trials and they were two clinical trials and although he does not think it will be until the 2030 that we might have the first artificial intelligence strokes on prescription. but it is important because worldwide, they are estimated to be i because worldwide, they are estimated to bei million because worldwide, they are estimated to be 1 million deaths from infections that cannot be treated by antibiotics. around the world and across the uk. this is bbc news. police scotland's chief constable has responded to a review of his force's culture by saying it is — institutionally — racist, sexist and discriminatory. sir iain livingstone said this didn't mean officers were prejudiced, but that acknowledging the issues was vital for change. scotland's first minister, humza yousaf, has said an admission is "monumental". the latest search in the hunt

for missing british girl madeleine mccann appears to have drawn to a close in portugal. briefing tents have been taken down and heavy machinery removed from the site at a reservoir in the algarve. officers spent three days searching the remote location, after information about the case was given to german prosecutors. british airways said that it had to cancel a number of flights at london's heathrow airport due to a technical issue. ba has suffered a series of reputation—damaging it failures in the past couple of years. you're live with bbc news. turning to another big story in the uk. new figures show net migration hit a record high in 2022. net migration is the difference between the number of people coming to live in the uk and the number leaving. our uk political editor, chris mason, has more.

migration, who we are, who and how many we welcome, from where, and for how long. this is great yarmouth, in norfolk, a community and region highly dependent on immigration. a town which overwhelmingly backed brexit. for years and years politicians have made bold promises about immigration and for years and years they've broken them. the political conversation from successive conservative prime ministers sounded like this. net migration to this country will be in the order of tens of thousands each year, no ifs, no buts. it's important we have net migration that is in sustainable numbers. we believe sustainable numbers are the tens of thousands. the numbers will come down because we'll be able - to control the system. the pledges of yesterday washed away by reality as those of today are spelt out.

there's been various factors and you will read the report, whether it's welcoming people here from hong kong and ukraine, that's had an impact, as we saw after the pandemic more people came back to study here who hadn't been here during the pandemic years. look, but fundamentally the numbers are high. i want to bring them down. today's extraordinary figures, including doubling the number of work visas since the pandemic, show that the conservatives have no plan and no grip on immigration. in the kings arms in caistor on sea, members of the local social club are having a lunchtime pint. so, is immigration too high? i myself have my grandmother who came up from estonia when the russians invaded, so i'm a product of that. i do think it's important that we take people in, people in need, but i think we've got to the point where we need to ease off a little. that fairness seems to be lost, it seems an influx of those who wish to come here to literally sponge off

us and not contribute. i think we need a certain influx to help us work this country, . in my opinion, so i don't think. you will ever get it down to zero. country after brexit, now that the government sancho neither government has control of it —— now that the government has control of the? -- now that the government has control of the ?_ -- now that the government has control of the ?— -- now that the government has control of the?_ a l control of the? they haven't. a desire to _ control of the? they haven't. a desire to be — control of the? they haven't. a desire to be a _ control of the? they haven't. a desire to be a century - control of the? they haven't. a desire to be a century for i control of the? they haven't. a desire to be a century for the l desire to be a century for the desperate for an ongoing desire for control too is the nature of emigration changes. how is my christian changed since brexit? i christian changed since brexit? i think since brexit, obviously free movement has been switched off so we are seeing _ movement has been switched off so we are seeing less than pre—brexit and what we _ are seeing less than pre—brexit and what we have seen in its place is that there — what we have seen in its place is that there are not some temporary

visa schemes in place. most migrants but may— visa schemes in place. most migrants but may he _ visa schemes in place. most migrants but may be different nationalities are being — but may be different nationalities are being able to move here because these _ are being able to move here because these visa _ are being able to move here because these visa routes are open to eu and non-eu _ these visa routes are open to eu and non-eu communities.— non-eu communities. video arrived decades ago — non-eu communities. video arrived decades ago as _ non-eu communities. video arrived decades ago as an _ non-eu communities. video arrived decades ago as an 18-year-old. i non-eu communities. video arrived l decades ago as an 18-year-old. when i looked in decades ago as an 18-year-old. when i looked in the — decades ago as an 18-year-old. when i looked in the train _ decades ago as an 18-year-old. when i looked in the train was _ decades ago as an 18—year—old. when i looked in the train was coming, i never_ i looked in the train was coming, i never saw— i looked in the train was coming, i never saw the _ i looked in the train was coming, i never saw the houses _ i looked in the train was coming, i never saw the houses looked i i looked in the train was coming, i never saw the houses looked like. j never saw the houses looked like. she now _ never saw the houses looked like. she now runs— never saw the houses looked like. she now runs a _ never saw the houses looked like. she now runs a care _ never saw the houses looked like. she now runs a care home - never saw the houses looked like. she now runs a care home in- never saw the houses looked like. | she now runs a care home in great yarmouth. their 42 residency here and 76 staff. yarmouth. their 42 residency here and 76 staff-— yarmouth. their 42 residency here and 76 staff. without india, we will not be and 76 staff. without india, we will rrot be here- _ and 76 staff. without india, we will not be here. and _ and 76 staff. without india, we will not be here. and without _ and 76 staff. without india, we will not be here. and without us, i and 76 staff. without india, we will not be here. and without us, the i not be here. and without us, the hospital— not be here. and without us, the hospital we — not be here. and without us, the hospital we have, _ not be here. and without us, the hospital we have, they— not be here. and without us, the hospital we have, they want i not be here. and without us, the hospital we have, they want us l not be here. and without us, thei hospital we have, they want us to take the _ hospital we have, they want us to take the patient's _ hospital we have, they want us to take the patient's and _ hospital we have, they want us to take the patient's and provide i hospital we have, they want us to take the patient's and provide our community— take the patient's and provide our community the _ take the patient's and provide our community the service _ take the patient's and provide our community the service when i take the patient's and provide our community the service when they| take the patient's and provide our- community the service when they want to -o community the service when they want to go on— community the service when they want to go on holiday— community the service when they want to go on holiday and _ community the service when they want to go on holiday and place _ community the service when they want to go on holiday and place the - to go on holiday and place the parent— to go on holiday and place the parent in— to go on holiday and place the parent in here _ to go on holiday and place the parent in here for— to go on holiday and place the parent in here for a _ to go on holiday and place the parent in here for a couple i to go on holiday and place the i parent in here for a couple weeks. sancho and hajit arrived from india two years ago. here they are caring for robert. migration promises people and places in our ongoing conflicted conversation over

what to do about it. chris mason, bbc news, on the norfolk coast. let's take a look at some other stories in the headlines. a fourth person has died after a stabbing and shooting attack in centraljapan. police were called to reports of a man who chased and stabbed a woman in the city of nakano. local media say the man then shot two officers with a rifle. the suspect has now been apprehended. the us state department has warned that china was capable of launching cyber attacks against critical infrastructure. a multi—nation alert recently revealed a chinese cyber espionage campaign aimed at military and government targets in the united states. beijing denies the accusations. tributes continue to be paid to the singer tina turner who died at the age of 83.

dire straits front man mark knopfler, wrote private dancer, the title track of her hugely successful comeback album in 1984. he then worked with her on her next two albums. he's been speaking with our entertainment correspondent colin paterson. # i'm your private dancer # a dancer for money # i'll do what you want me to do.# mark knopfler. what was it about tina turner that made her so special? absolute life force, a human dynamo. i'd never met anybody like tina. # i want to make $1 million # i wanna live out by the sea...# how did your track private dancer end up on her album? i'd written private dancer as a signal for respect being accorded to everybody in society, and tina made it the song it is. i wasjust mumbling along. you know, mine was a kind of smoky club style of an approach, but tina's was just fists and,

you know, seismic. it ends up being a triumphant cry for people with diminished rights everywhere. # i'm your private dancer # a dancer for money # i'll do what you want me to do...# because the way private dancer and the making of the album is described is that she was given two weeks to assemble this album by capital, and it sounds like a rally cry went around the record industry, like who can help tina turner. is that how you remember it? yes, that is how i remember it. there really was. private dancer was looking for a home. you've talked about the way how she made songs her own. i think a lot of people are onlyjust realising that what's love got to do with it was first done by bucks fizz. # what's love got to do...# # what's love but a second—hand emotion...#

she had a way of transforming songs so that she owned them. they were hers, increasing the resonance of it so that it was resonating with millions of people. so finally, how will you remember tina turner? 0h, i'lljust always remember, in spite of all the things that happened to her. pure happiness. joy — pure, unadulterated joy at life. mark knopfler, thank you very much for speaking to us about your memories of tina turner. my pleasure. and a big surprise for a high school class in florida, superstar ed sheeran turned up at the music department at middleton high school. the band are so focused, they don't even stop playing. ed gave them guitars, tickets to his show, and then treated them to a special classroom concert. i'm going to play a tiny concert now if that's ok. # for me

# darling just dive right in # follow my lead...# that's all for now — stay with bbc world news. hello there. from a blue sky, sonny started for the yorkshire area and as soon as we had 17 because these cumulus clouds as the air started to rise in this area of warm air in the atmosphere, the cloud started to spread out and ljy the cloud started to spread out and by the time we got to the early afternoon, it turned pretty cloudy. and that kind of thing you can see happening here on the satellite picture from thursday look at this area of cloud just expanding it to the course of the afternoon. and we are probably going to see the sort of thing happening on friday as well. and a few patches of cloud

still in areas of lincolnshire otherwise most of us, we've got clear skies around seven to nine celsius. on friday, for many of us it is going to be a sunny start to the day with blue skies with us first thing in the morning. late morning, that's what we had 17 degrees and that's mr the clouds develop in parts of yorkshire prone to seeing some of those clouds spreading across the skies and northwest and having a bit more cloud in if your brakes in northern ireland and for most it is a dry day with sunny spells and spirits of the low 205 and spots with 5unny spells and spirits of the low 205 and spots will be pleasant. on to the weekend, we do have a court from desk is quickly running into our area of high—pressure defect in northern areas and so, expect more the way of scotland to be a for the highlands. and going into northern scotland and temperatures ju5t into northern scotland and temperatures just two to the afternoon on saturday for the south,

more 5un5hine it'5 afternoon on saturday for the south, more 5un5hine it's going be a warmer day with temperatures in the low 205. to yet about 23 or 24 degrees. heading into sunday, the high—pressure i5 heading into sunday, the high—pressure is still there in the ki55er 5unny 5pell5 coming and going but the cloud. the highest interest continues to be across western area5 continues to be across western areas in the southeast of wales and simplest england, i skated around 26 or 27 degrees. turning glib equipment across northern and eastern areas that's the case of the bank holiday with temperatures down a few degrees but still feeling warm and that strong may sunshine. that is your latest weather.

this is bbc news. we'll have the headlines and all the main news stories for you at the top of the hour, as newsday continues straight after hardtalk. welcome to hardtalk, from south africa. i'm stephen sackur, and this is the south african parliament in cape town, dominated since 1994 by the african national congress. but could the anc�*s grip on power be loosened? well, the once unthinkable mayjust be possible.

the anc has been damaged by economic stagnation,