the hijab correctly in public. and a video message from australias women's football team. as the world cup kicks off this week, the co—hosts demand equal prize money with the men. on bbc london... underdiagnosed and misunderstood. on newsnight at 10:30pm, a disturbing report on how ai is being used to create child sexual abuse imagery. we will speak to the tory peer trying to bring the online safety bill in line with rapid technological advances. good evening. scientists are calling it a breakthrough — an enormous moment of hope. trials of a new drug to treat alzheimer's show it can slow the progression of the disease by about a third — if patients are treated early enough. almosti million people in the uk are estimated to be living with dementia. around two—thirds of

them have alzheimer's. it's a diseaese that gradually destroys key areas of the brain involved in memory and understanding. but there are questions about the cost and safety of the new drug. our medical editor, fergus walsh, spoke exclusively to one of the patients on the trial. hello. are you all right, mr colley? hi, yes, thank you. i've got your donanemab here for you... mike colley has alzheimer's disease, yet the 80—year—old feels incredibly fortunate. i'm one of the luckiest people you'll ever meet. just for this. that's because he's been on the global trial of donanemab for two years. he's come with his son for his monthly infusion, at this clinic in london. i seem to get more confident every day. and i'm sure this is going to be successful. they'll get all the rubbish off the top of my brain and i'll

be back to normality. i'm very confident about that. i never thought that i would see my dad just so full of life again. you know, now we have hope and, two years ago, we didn't. and, you know, that'sjust an incredible difference. i'd like you to subtract seven - from 100, and keep subtracting seven from each answer until i tell you to stop _ so what is 100, take away seven? 93. despite mike's optimism, donanemab is not a cure. his memory and ability to process information are still impaired. 86... but full results of the trial show the drug slowed cognitive decline by about a third, enabling many patients to continue leading independent lives for longer. 60... he chuckles i've forgotten already now. i've lost the plot, sorry. that's ok. in alzheimer's, a rogue protein called amyloid builds up around

neurons, destroying connections. donanemab is an antibody which binds to amyloid. this prompts immune cells to attack and clear amyloid from the brain. so, lots of toxic amyloid protein... you can see it clearly in these scans. this patient starts with a lot of amyloid — shown in green, yellow and red — but after six months on donanemab, most of the amyloid has been removed. this is really significant. i mean, this is one of the biggest breakthroughs, in so much as this disease is a pandemic. it's getting more and more common. and being able to both remove the amyloid protein and demonstrate that that correlates with the slowing, or hopefully steadying of symptoms, is life—changing. so a moment of hope? a moment of enormous hope. this is fantastic. hello. are you ready to come through? yes. all right.

donanemab could be licensed here within a year, butjanet north is hoping to get it sooner, as part of the next stage of trials. could you tell me what year it is? oh, dear. she sighs no. 2004, i was going to say, but it's 2020—something, isn't it? 2024? 0k... janet, who's 76, says alzheimer's means she no longer remembers how to use a computer or how to cook. i can't make things nice. i can't cook as i want to cook. i have no timing ability, and that's crucial. erm, itjust drives me potty, because i can't do it. but before any patient gets donanemab, they have to have one of these — a pet scan, a specialised type of brain scan.

the problem is, there aren't nearly enough scanners. currently, hardly any alzheimer's patient has one. there's another hurdle. donanemab has potentially serious side effects. it can cause swelling and bleeding in the brain, so patients will need to be aware of the risks and be carefully monitored. but despite safety concerns, there will be huge demand for this new drug, which mike will continue to receive as long as it helps him. after decades of failed trials, the era of alzheimer's treatment is upon us. and fergus is here now. it isa it is a very cruel disease, this drug definitely has benefits but what about the risks? just drug definitely has benefits but what about the risks?— drug definitely has benefits but what about the risks? just over 850 atients what about the risks? just over 850 patients received _ what about the risks? just over 850 patients received donanemab - what about the risks? just over 850 patients received donanemab on . what about the risks? just over 850 l patients received donanemab on this trial and of those, three people died as a result of the treatment

due to brain swelling or bleeding. so the risks and benefits will need to be carefully assessed by regulators, who are already looking at donanemab and families will need to make that assessment. but for many, faced with a partner or parent in the early stages of alzheimer's, this drug could help a loved one stay independent for longer and as you saw in my report with mike and his family, it offers hope to those faced with these awful disease. there is a second alzheimer's which works in a similar way which is going through the approval process. it is already licensed in the us, where it costs 21,000 pounds a year. that gives you a ballpark figure for how much these drugs will cost here. worth noting that half the patients on donanemab were able to give up the drug within a year. these drugs are not a cure, the benefits are modest but i predict there will be a clamourfor modest but i predict there will be a clamour for both of them if and when

they are approved. a£111" clamour for both of them if and when they are approved-— they are approved. our medical editor, fergus _ they are approved. our medical editor, fergus walsh. - they are approved. our medical editor, fergus walsh. thank . they are approved. our medical i editor, fergus walsh. thank you. lots more online including a piece featuring interviews with some of those with dementia and their families. they share their tips for living with the condition, how to talk to people with dementia and how they have learned to adjust to their changing brains. that is at... this was greece today as firefighters battled wildfires that forced residents and holiday—makers to flee coastal towns south of athens. more than 1,000 children had to be moved out of holiday camps there. it comes a blistering heatwave is intensifying in various parts of the world including large swathes of europe, where the highest temperatures recorded today were in sicily and southern spain. across the atlantic — in death valley — already one of the hottest places on earth — it reached more than 50 degrees. in china, the country's hottest ever temperature

was recorded in shing jiang — 52.2 degrees. in a moment we'll hear from our climate editor justin rowlatt, but first, nick beake reports on the situation in greece. a thick blanket enveloped the hills outside of athens. wildfires powered by heavy winds. the flames rapidly advancing on homes. there were small victories for those fighting from the air, but it's been a constant battle to contain the pockets of firejumping up, as temperatures reached 44 celsius in some parts of greece. near the capital, more than 1,000 children were forced to abandon their summer camp. "there are about 1,500 kids who need to be bused to safety", a local official explained. saying they'd been found emergency accommodation for the night. as dark plumes ominously filled the horizon, many decided to escape. at these stables,

a race against time — disorientated and distressed, but all rescued. there wasn't much in it. this is what they left behind. tonight, firefighters across the athens region are on high alert. greece's first major heatwave for the summer has now ended but another is on the way. nick beake, bbc news. and there are wildfires here in spain, too. 4,000 people had to be evacuated as 300 firefighters fought to control a blaze on la palma, in the canary islands. this man says if a friend hadn't phoned to warn him, he would have died in the inferno. it comes as a second blistering heat wave sweeps into europe. temperatures in southern spain are pushing into the 40s, 10 celsius hotter than normal in places. it makes it almost

unbearable to work outside. it's been extremely hot this year. like, i normally get up at eight or nine in the morning but i've been getting up at five just to get things done by 9.00 because it's just harsh. make you feel a bit better. colin runs an animal sanctuaryjust inland from the tourist beaches of the costa del sol. there you go. hot animals mean more work for him. you've got sweat all over you. they need to be hosed down to keep them cool and it's too hot for the tourists too — his main source of donations. the only animals that seem to be enjoying themselves are the meerkats. so colin has had to close the place and the cash is running out. i think we'lljust have to just... bear with itjust now and just see what happens. this year's just been unbearable, it really has. you get no break from it at all. here's why it's so hot. a high—pressure system, held in place by thejet stream, a rapidly moving flow of air high

in the atmosphere, is funnelling heat up from the deserts of north africa and across southern europe. the climate of southern europe is changing, say local people. it's becoming more and more like north africa. the sahara desert is slowly creeping into europe. the weather is being turbo—charged by climate change, say scientists. humans are 100% to blame for the global trend in high temperatures that we are seeing. so all of the observed global warming is because of our burning of fossilfuels. and it's notjust hot in europe. china is reckoned to have recorded its highest temperature ever yesterday — 52.2 degrees celsius. and tens of millions of people are under extreme heat warnings in the us too.

it is 11 o'clock at night here in southern spain and there is a temperature reading on the building just over there that says 30 celsius. 30 celsius! night—time temperatures are not something we often discuss when we talk about extreme heat but during the southern european heatwaves it's been in the late 20s or early 30s all night, so there is no respite. that explains why it can take such a terrible toll on human health.— why it can take such a terrible toll on human health. sophie. just thank ou. the head of a public inquiry into the post office scandal, which was caused by a faulty computer system, has called for action to help those involved receive full and fair compensation. between 2000 and 2014, hundreds of sub—postmasters were wrongly prosecuted for theft or false accounting, some were sent to jail. many of the victims say they're still waiting — years later — for proper compensation. our business correspondent, emma simpson, has more. another set of boxes arrive

to pack up their belongings. this former sub—postmistress and her family are about to be evicted. her landlord's selling up. seema misra was wrongly prosecuted for stealing from her post office. she was pregnant when sent to prison in 2010. financially, we lost everything. we lost the business, we lost the property in london. there is no price tag to it. her conviction�*s now quashed, but she's still waiting for her full compensation. it's getting urgent now. i'm scared, to be honest, i'm really, really scared. fighting the post office is torture, and getting compensation is another torture. you don't have any faith left into the way it's been dealt with. the chair of the public inquiry isn't happy how things are going either. what has emerged is a patchwork quilt of compensation schemes. and, unfortunately, it is a patchwork quilt

with some holes in it. sir wyn�*s taking a big interest in compensation here in this inquiry room. some fear it's becoming a scandal within a scandal, from victims being taxed on their awards to money being used to pay bankruptcy debts, to delays, and a looming deadline for the government's new scheme. today's recommendations aim to fix this. sir wyn williams has taken the gloves off, and he has told the post office, the part of the business, that he will tolerate no more delay, obfuscation or obstacles in the path of compensation. | well, let's turn now to the ceo | of the post office, nick read... today, he told the bbc he welcomed today's report, and they're working as fast as they can. i think what has become extremely apparent is the scale and complexity of this is more than we thought, and much more than we thought. seema's just desperate to get what she's owed, to buy her own house and finally put the nightmare behind her.

emma simpson, bbc news, woking. president putin says he'll respond to what he's called a "terrorist act" which crippled the strategically important kerch bridge, which links russia with the annexed region of crimea. the russian president blamed ukraine for the attack. ukrainian media has reported military drones were used. our russia editor, steve rosenberg, reports from moscow. some call it russia's most important bridge, but look, you can see the roads split and sloping. russia says ukrainian naval drones struck at night. two people were killed in the explosion. the bridge, linking mainland russia with annexed crimea, is a vital supply route for moscow. president putin promised to retaliate. translation: this is another - terrorist attack by the kyiv regime. it was a pointless crime,

from a military standpoint, and a brutal one. russia will, of course, respond. the defence ministry is drafting proposals. same bridge — last autumn. russia accused ukraine of carrying out this attack too. ukraine says the bridge is illegal. the 12 mile long bridge is not only strategically important to the kremlin, it's hugely symbolic. when it opened in 2018, vladimir putin was first to cross — as if to show the world that russia and crimea were nowjoined for ever. so for the second time in less than a year, the bridge that vladimir putin built, this symbol of russia's annexation of crimea, has come under attack. the kremlin says it will respond by continuing with what it still calls the "special military operation", russia's war in ukraine. but what the kremlin won't be continuing, it said today, is with the deal that it kept global

food prices stable. brokered by the un, the agreement allowed ukraine to keep exporting grain via the black sea. moscow, though, says it's not getting what it was promised and will no longer guarantee the safety of shipping. the kremlin insists its decision isn't connected to the attack on the bridge, but right now, it appears in no mood for compromise. steve rosenberg, bbc news, moscow. there's been a warning today that artificial intelligence is making it harder to identify children at risk of sexual abuse. we'll hear from the head of the national crime agency in a moment, but first, our technology editor, zoe kleinman, looks at some of the key issues being brought to light in the new age of ai. the world is waking up to the potential and the dangers of the most advanced forms of artificial intelligence. across the globe, countries

are racing to try to both harness and regulate this technology. if we keep feeding these systems more and more computing resource, more and more data, and we keep having stronger and stronger incentives, you know, for the private sector to accelerate this stuff, when do we cross a line when these systems become dangerous in a new way? there is another threat, isn't there, which isjobs? there will be winners and losers on a kind of global basis in terms of where the jobs are as a result of ai. artificial intelligence is developed in a computing system called neural networks, inspired by the complex connections between the cells in human brains which enable us to think. ai systems are rapidly improving as they are trained on increasingly vast datasets — huge libraries of information which allow them to identify patterns and solve problems, and even learn from their own mistakes. it's got huge potential for good. for instance, in health care, spotting cancer and discovering new drugs.

the uk does great when it comes to research and has some brilliant universities, but the oddest truth is that there isn't quite enough of a culture of risk—taking or reward forfailure and encouragement of failure that really enables you to build outside successes. that's why i relocated to palo alto in silicon valley. it's a balancing act that the world can't get wrong. maximising the benefits and minimising the risks of ai while ensuring that no single company, country or the tech itself grows too powerful. zoe kleinman, bbc news. the head of the national crime agency has warned that artificial intelligence is making it harder to identify children at risk of sexual abuse. graeme biggar was speaking in an annual speech, outlining the biggest crime threats facing the uk. obviously artificial intelligence is providing brilliant opportunities for society and indeed for law enforcement as well,

to investigate crime better. but it is also being used by paedophiles to now create hyperrealistic images of children. they have used previous ai products to try and create deep fake videos but not to the same extent as they can now, and this causes a problem for us in two ways. one, it massively increases or gives the potential to massively increase the amount of images that are out there, which mean it's harder for us to identify who are real children that we can find and protect. then by increasing the amount as well, it also further normalises that behaviour and leads to further abuse, as i mentioned. the head of the national crime agency speaking there. angus crawford is here. you reported on thisjust a couple of weeks ago — what did you find? we found three things. first, paedophiles are using ai image generator is to create vast amounts

of photorealistic images of child sexual abuse. second, they are advertising them for sale on social media platforms in groups there. and third, they are selling them on mainstream platforms, offering monthly subscriptions for as little as £3. the authorities are really concerned about this. what is the solution? there are some products out there, programmes that can detect ai imagery but they are not widely deployed or developed, so that leaves the image is still out there, it leaves the means of making them still out there and law enforcement playing catch up. thank ou. in iran, the authorities have announced they'll be restarting patrols by the morality police to ensure women wear the hijab correctly in public. its been ten months since the death of 22—year—old mahsa amini while she was being held by the morality police. huge protests erupted nationwide and many women stopped wearing the headscarf in public places as an act of protest.

our diplomatic correspondent caroline hawley reports this would have been unimaginable in iran before september last year. but growing numbers of women have been defying the regime by not covering their hair in daily acts of rebellion. but, now, a chilling response from the regime. translation: police patrols will be | established throughout the country. j these officers will deal with those who unfortunately ignore the consequences of not wearing a proper hijab and insist on disobeying the rules. video was released today by a news agency affiliated with iran's revolutionary guards with a very clear message. the women in the black chadors are the enforcers, making sure people cover up their hair. over the past few months, some businesses have been closed down when their customers were caught unveiled. but the regime had taken the morality police off the streets as it struggled to contain mass protests that erupted

after the death of mahsa amini. she'd been stopped for allegedly not wearing her hijab properly. witnesses say she was beaten before she went into a coma and died. the unrest that followed was the biggest challenge to the regime since the islamic revolution of 1979. met with a brutal crackdown, the street protests have largely petered out, leaving for many a simmering fury against the authorities. this lady is an iranian women's rights advocate now living in exile. i asked her why she thought the regime was resuming morality police patrols now. they are scared. they know that... they know that the wall that they created, all those oppressive systems that they created in the past 44 years, it's cracked and it's going to fall any moment. so they are trying to do the damage control. for more than four decades, the iranian regime has tried to control how women dress

and behave, but they've been losing the battle. translation: do you think. the morality police can prevent women from not wearing a hijab? they cannot impose it like before. the number of people who do not obey is too high now. they cannot handle all of us. iran is not the same country it was before last september. a new generation is no longer willing to conform. but with morality patrols resuming, what price may they pay? caroline hawley, bbc news. the first space tourists travelling on sir richard branson's virgin galactic will launch next month, with an 80—year—old man and a mother and daughter on board. keisha schahaff, from antigua, won her place in a raffle. her daughter anastatia mayers, a student at aberdeen university, is going with her. and with them will be 80—year—old jon goodwin — an olympian — who bought a ticket for the virgin space mission 18 years ago and has been waiting ever since.

ellie price reports. the spaceship attached to a mothership... as bucket list dreams go getting into space is a difficult one. when i was two years old, just looking up in the skies, i was like, "how can i get there"? it turns out a raffle ticket will do it. keisha and anastatia from antigua will be the first mother and daughter to blast into orbit together. jon goodwin from newcastle under lyme, who's 80, has beaten the odds in another way. he's got parkinson's. i was pretty convinced that they were going to turn round to me and say, "you're not able to go". but they have been fantastic. the fact that i can defy my parkinson's. three years ago, i climbed kilimanjaro and cycled downjust to prove that it wasn't going to get me. and this is the same thing. an olympic canoeist in 1972, he knows a challenge.

release, release, release. plane released. but despite this flashy promotional video, john remains pretty down to earth about his trip. even if he did pay $250,000 for a ticket 18 years ago. i think the opportunity to do something that's not been done before by many people at that price is a real bargain. the flight will lift off on august the eighth. ellie price, bbc news. just days before the women's football world cup kicks off in australia and new zealand , the australian team , known as "the matildas" , have demanded equal prize money with the men's game. around £84 million will be shared out among women's teams competing at this year's tournament, but that's just a quarter of what the men receive. fifa's president says the "ambition" is for equal prize money by 2027. katie silver reports. in 2015, fifa made us play the world cup on artificial pitches. the grass was fake and the disrespect was real.

in 2013, we signed a new deal to make sure we got our laundry done for us. fifa will still only offer women one . quarter as much prize money as men for the same achievement. members of the home team, the matildas, make their appeal to fifa and football's power brokers just days before the world cup kicks off. all: this is our legacy. the soaring popularity of the women's game in australia has been on full display. 2 billion people globally are expected to tune in to watch this world cup, yet the prize money forfemale players is far smaller than the men's. the argument for why we are getting paid so much less is just kind of dwindling, is just kind of dwindling, it's not really much it's not really much of an argument any more. of an argument any more. if you look at the ticket sales if you look at the ticket sales and the interest and the tv and the interest and the tv viewing and all of that, viewing and all of that, there's just not much there's just not much of an argument there any more. of an argument there any more. in 2015, the players were paid 15 million by fifa. in 2019, it was 30, and in 2023

it's gone up to 110. it's improved, but there's room for improvement. equal pay is a real challenge for women in football... - for those that follow the game closely, this world cup is being seen as a watershed moment for women's pay. one of the most exciting parts of the 2019 women's world cup was after the final was won by the usa, there were chants of, "equal pay," that rang around the stadium. so this women's world cup coming up, it's a real, another opportunity to be able to talk about these bigger things and equal pay, it's still something that notjust women footballers are striving for, it's what women everywhere are striving for. this world cup there have been stand—offs between multiple teams and their football associations, including the uk, south africa, nigeria and canada, and these fights are over everything from basic equal pay to bonuses. some teams are even threatening to boycott matches if their demands are not met. it's hoped that with this momentum,

the next—generation's battle will be just on the pitch. katie silver, bbc news, sydney. time for a look at the weather. here's ben rich. an extraordinary weather map. one of the big questions, is any of that heat heading our way? the answer is a resounding no no but thatis the answer is a resounding no no but that is good news because these are the temperatures we saw today, close to 45 in the south of spain. this is dangerous and in some parts of southern europe, they are set to return hotter in the next few days but we are locked away from that heat by the jet stream keeping us in this flow of cooler air and low pressure in charge. things are much cooler, unsettled. today we saw a scattering of heavy showers, many of those fading but we have more cloud scattering of heavy showers, many of those fading but we have more cloud and rain gathering to the west and and rain gathering to the west and as we head through the rest of the as we head through the rest of the

night, some of night, some of that rain will push in across parts of northern ireland,