on a vital brdge, linking russia and crimea. but first, the international reaction to russia's pulling out of an international grain deal has been widespread, and swift. the black sea grain deal let ukraine ship its grain by sea, despite moscow's naval blockaide. despite moscow's naval blockade. the kremlin�*s spokesman says the agreement has been halted until russia's demands are met. but ukrainian president volodymyr zelenskyy remains defiant, saying his ships will sail without russian approval. let's take a quick look at the deal itself — ukraine is one of the world's largest exporters of key crops, including sunflower, maize, wheat and barley. when russia invaded ukraine, in february of 2022, its navy blockaded the country's black sea ports. that trapped 20 million tonnes of grain, sending global food prices skyrocketing. injuly last year, the un and turkey brokered a deal to get grain flowing again. when shipments restarted, world food prices declined by about 20%.

since then, ukraine has exported 32.8 million tonnes of grain and other food. un secretary general anthony guterres sharply criticized russia's move. today's decision by the russian federation will strike a blow to people in need everywhere. the unimpeded access to global markets forfood products and fertilisers from both ukraine and the russian federation. our goal must be continuing to advance global food security and the global food price stability. this will remain the focus of my efforts, taking into account the rise in human suffering that will inevitably result from today's decision. our correspondent nomia iqbal has been covering the un security council meeting in new york. there's been condemnation of russia's decision not to extend the grain initiative. the uk foreign secretary james cleverly, who was heading

the security council meeting, accused vladimir putin of using food as a weapon. earlier today, the un secretary general antonio guterres also expressed disappointment and condemned the decision, and issued dire warnings about the impact that it could have on many countries. russia hit back at the meeting. a spokesperson, to quote, called the west accomplices of the kyiv terrorists and they confirmed that the grain initiative won't be extended until, to quote the spokesperson, that the west meets its demands, so russia's food and fertiliser exports, they say, are being affected as a result of western sanctions, not directly, but indirectly, they say, due to restrictions on payments, logistics and insurance. in terms of what comes next, it's unsure. ukraine's grain association said it had been prepared for this to happen, for the deal to expire, so shipments had fallen,

no new vessels had been initiated. they are looking at some options, such as looking to use ports in the river danube to carry out exports, but as of yet, there is no concrete decision or plan on what comes next. meanwhile, president putin says he'll respond to what he's called a "terrorist act" that crippled the strategically important kerch bridge. it links russia with the annexed region of crimea. the russian president blamed ukraine for the attack. ukrainian media reported military drones were used. our russia editor steve rosenberg reports from moscow. some call it russia's most important bridge, but look, you can see the roads split and sloping. russia says ukrainian naval drones struck at night. two people were killed in the explosion. the bridge, linking mainland russia with annexed crimea, is a vital supply route for moscow. president putin promised to retaliate. translation: this is |

another terrorist attack by the kyiv regime. it was a pointless crime, from a military standpoint, and a brutal one. russia will, of course, respond. the defence ministry is drafting proposals. same bridge — last autumn. russia accused ukraine of carrying out this attack, too. ukraine says the bridge is illegal. the 12 mile long bridge is not only strategically important to the kremlin, it's hugely symbolic. when it opened in 2018, vladimir putin was first to cross, as if to show the world that russia and crimea were now joined for ever. so for the second time in less than a year, the bridge that vladimir putin built, this symbol of russia's annexation of crimea, has come under attack. the kremlin says it will respond by continuing with what it still calls the "special military "operation", russia's war in ukraine.

but what the kremlin won't be continuing, it said today, is with the deal that it kept global food prices stable. brokered by the un, the agreement allowed ukraine to keep exporting grain, via the black sea. moscow, though, says it's not getting what it was promised, and will no longer guarantee the safety of shipping. the kremlin insists its decision isn't connected to the attack on the bridge, but, right now, it appears in no mood for compromise. steve rosenberg, bbc news, moscow. i'm joined byjane harman, president emerita at the wilson center. good evening to you, thank you very much forjoining us on our programme tonight. us on our programme tonight. sources in the ukrainian security services have confirmed to the bbc that it was responsible for this bridge attack. white house spokesperson john kirby was asked about this earlier. here's what he said. crimea is

ukraine. we don't tell them what is or isn't legally a legitimate target. they determine their targets for themselves. do you think it's fair to call this a legitimate military target? yes, i do. supplies for the illegal war effort started by russia against ukraine come over that bridge. it's been attacked twice now by ukraine. they've acknowledged this attack, and i think they may have acknowledged the last attack, and my understanding is russia is blaming the russian military for not being able to protect this bridge into what they call their territory. i think it's fair game. ukraine is trying to end this war with victory. they should. they claim, this is their call, that crimea is still part of ukraine, and i see no evidence that it isn't. it is part of

independent ukraine, and ukraine is trying to defend it and defend its public against and defend its public against an outrageously illegal attack. we know that this is an important logistical supply route for the russians. the kremlin does expected to be fully operational again before the end of the year, so how does damaging this bridge actually change ukraine's counteroffensive?- actually change ukraine's counteroffensive? well, it makes it _ counteroffensive? well, it makes it more _ counteroffensive? well, it makes it more effective i counteroffensive? well, iti makes it more effective at least until the end of the year. i gatherfrom your reporting, which sounds right, that russia's retaliating in part by now going back on this agreement that was brokered by the un and turkey to export ukrainian grain to russia. think about that. what is russia really doing by taking this step? yes, it's punishing ukraine �*s economy, but it's sending a message to africa, which has massive food insecurity, that russia doesn't want to help. i thought russia was trying to build bridges in

africa, no pun intended from the other bridge, the kerch bridge, but i think this is a really unproductive move, and i also think it's an opportunity for president and again to try to —— president erdogan to try to —— president erdogan to try to broker a change. he wasjust in vilnius remember, and he committed, backed up his suggestion to sweden joining nato, and he also wants turkey to be part of the eu, if he is a good citizen here and tries to broker a change in russian behaviour, this might help his case. i behaviour, this might help his case. ., ., ., ., case. i want to ask you about this black — case. i want to ask you about this black sea _ case. i want to ask you about this black sea grain - this black sea grain initiative, because the former nato supreme allied commander tweeted this raises a risk of a direct confrontation between nato, because nato might decide it needs to escort these ships through the black sea. so how should the us and nato respond

to this? ~ ., �* ~ ., to this? well, i don't know what nato _ to this? well, i don't know what nato will _ to this? well, i don't know what nato will do, - to this? well, i don't know what nato will do, it's - to this? well, i don't know what nato will do, it's a i to this? well, i don't know. what nato will do, it's a nato decision. remember, the us is part of nato, and if conversations are going on, they are going on at the moment, not in public. nato could decide to do that, the un could decide to do that, the un could decide to do that, the un could decide to do this. there was a un brokered deal after all, or let's go back to turkey. turkey is a member of nato but nato as the broker of the deal could decide to escort ships. 0ne the deal could decide to escort ships. one of turkey's borders is on the black sea, so can claim that this is international waters and turkey is protecting freedom of the sea next to turkey. sie don't think there _ sea next to turkey. sie don't think there is _ sea next to turkey. sie don't think there is necessarily - sea next to turkey. sie don't think there is necessarily the risk of a direct confrontation here if the us decides with its nato allies to step in? i here if the us decides with its nato allies to step in?- nato allies to step in? i don't know. putin _ nato allies to step in? i don't know. putin can _ nato allies to step in? i don't know. putin can make - nato allies to step in? i don't know. putin can make any . know. putin can make any argument he wants. he can claim right now that because of us sanctions, the us is at war with russia. i think the cost

to him of doing that are very high, and so i don't think he's going to do it. i also think the cost of using nuclear weapons in any form are very high, and he's been warned by china not to do this. so i don't know how much information actually gets through to him, and whether there is anyone telling him how isolated he is, and how poor his decision—making is, but at any rate, i don't think so far as i know, that this decision has been made by nato, and i don't know whether it would provoke a war against nato. i think the state for putin, his army is degraded, his troops are untrained and he has no friends. maybe china, but i don't think china would want to venture into this mess over the black sea exports of grain, because china is starting to make friends with africa, too. so it is certainly complicated, certainly in the geopolitical sense. you are the chair of a commission on the national

defence strategy, which is this bipartisan commission investigating president biden�*s defence strategy, how to implement it, and you co—authored a piece last month saying that,... so, do you think that means that the us is at the moment unable to keep supplying ukraine with what it needs on the battlefield?— ukraine with what it needs on the battlefield? well, yes and no. i the battlefield? well, yes and n0- i mean. — the battlefield? well, yes and no. i mean, there _ the battlefield? well, yes and no. i mean, there are - the battlefield? well, yes and no. i mean, there are still- no. i mean, there are still things that we are producing. certainly cluster munitions, which we are going to provide, and i think it is a close case that we should do that, but we don't have regular ammo to provide, and those munitions would just be used on ukraine �*s soil, and ukraine would hopefully dismantle the after—effects of those munitions, so people wouldn't be had. that's one thing. we also do have these longer range

missiles to provide and we have f-igs, missiles to provide and we have f—igs, which we have said we will provide up to the ukrainian pilots are trained. but is there an issue about the defence industrial base in the us having the ability to produce what we will need for future wars? yes, there is an issue and we are going to point that out in my commission, and on a bipartisan basis, and hopefully we will come up with some very targeted suggestions about how that base can be beefed up, let's understand that future wars will depend much more on advanced technology than past wars, and one goal is to reduce dependence on vulnerable legacy systems, which were good for fighting the last war, and increase our production of technology and technology connected weapons that will win the next war. connected weapons that will win the next war-— the next war. jane harman, thank you — the next war. jane harman, thank you so _ the next war. jane harman, thank you so much - the next war. jane harman, thank you so much for- the next war. jane harman, i thank you so much for sharing your thoughts with us tonight. thank you.

around the world and across the uk, this is bbc news. bbc news, bringing you different stories from across the uk. greater manchester police are searching for illegal cosmetic medicines and treatments, including facial fillers. they suspect there may also be links to money—laundering. also be links to money-laundering. the investigation _ money-laundering. the investigation today - money-laundering. the investigation today is i money—laundering. tie: investigation today is around conspiracy to supply illegal medicines or licences to medicines. we expect them to be imported from korea and china and these individuals are distributing them to names of the community.— distributing them to names of the community. two people at this preperty _ the community. two people at this property were _ the community. two people at this property were arrested . this property were arrested while a third person was arrested in another raid. police found a bag of cash, containing £30,000 and a number of other assets were taken away. including an expensive car. , , ., . , away. including an expensive car. , , ., . away. including an expensive car. , car. these products are sold oane, car. these products are sold online. via _ car. these products are sold online, via an _ car. these products are sold online, via an illegal- car. these products are sold | online, via an illegalwebsite. online, via an illegal website. members_ online, via an illegal website. members of the public unwittingly can go and buy them, _ unwittingly can go and buy them, without realising that them, without realising that the product they are being supplied with is unlicensed. so they— supplied with is unlicensed. so they have _ supplied with is unlicensed. so they have not gone through the rigorous — they have not gone through the rigorous checks of safety,

quality _ rigorous checks of safety, quality and effectiveness. for more stories _ quality and effectiveness. fr?" more stories from across the uk, head to the bbc news website. you're live with bbc news. millions of people around the world are struggling with unrelenting heat across three continents. parts of the us and china have both topped 50—degrees celsius — that's about 122 degrees fahrenheit — and the mercury in europe just keeps rising. in a moment we'll hear from our climate editor justin rowlatt, but first our correspondent nick beake reports on the situation in greece. a thick blanket enveloped the hills outside of athens, wildfires powered by heavy winds, the flames rapidly advancing on homes. there were small victories for those fighting from the air, but it's been a constant battle to contain the pockets of fire jumping up, as temperatures reached 44 celsius in some parts of greece. near the capital, more than 1,000 children were forced to abandon their summer camp.

"there are about 1,500 kids who need to be bused "to safety," a local official explained, saying they'd been found emergency accommodation for the night. as dark plumes ominously filled the horizon, many decided to escape. at these stables, a race against time — disorientated and distressed, but all rescued. there wasn't much in it. this is what they left behind. tonight, firefighters across the athens region are on high alert. greece's first major heatwave for the summer has now ended but another is on the way. nick beake, bbc news. and there are wildfires here in spain, too. 4,000 people had to be evacuated as 300 firefighters fought to control a blaze on la palma, in the canary islands. this man says, if a friend

hadn't phoned to warn him, he would have died in the inferno. it comes as a second blistering heatwave sweeps into europe. temperatures in southern spain are pushing into the 405, 10 celsius hotter than normal, in places. it makes it almost unbearable to work outside. it's been extremely hot this year. like, i normally get up at 8:00 or 9:00 in the morning, but i've been getting up at 5:00 just to get things done by 9:00, because it'sjust harsh. make you feel a bit better. colin runs an animal sanctuary just inland from the tourist beaches of the costa del sol. there you go. hot animals mean more work for him. you've got sweat all over you. they need to be hosed down to keep them cool, and it's too hot for the tourists, too, his main source of donations. the only animals that seem to be enjoying themselves are the meerkats.

so colin has had to close the place and the cash is running out. i think we'lljust have tojust... ..bear with itjust now and just see what happens. this year's just been unbearable, it really has. you get no break from it at all. here's why it's so hot. a high—pressure system, held in place by the jet stream, a rapidly—moving flow of air high in the atmosphere, is funnelling heat up from the deserts of north africa and across southern europe. the climate of southern europe is changing, say local people. it's becoming more and more like north africa. the sahara desert is slowly creeping into europe. the weather is being turbo—charged by climate change, say scientists. humans are 100% to blame for the global trend in high temperatures that we are seeing. so all of the observed global warming is because of our burning of fossil fuels. and it's notjust hot in europe.

china is reckoned to have recorded its highest temperature ever yesterday — 52.2 degrees celsius. and tens of millions of people are under extreme heat warnings in the us, too. scientists are calling it a breakthrough, an enormous moment of hope. trials of a new drug to treat alzheimers show it can slow the progression of the disease by about a third, if patients are treated early enough. it's a disease that gradually destroys key areas of the brain involved in memory and understanding. but there questions about the cost and safety of the new drug. 0ur medical editor fergus walsh spoke exclusively to two of the patients on the trial. hello. are you all right, mr colley? hi, yes. yes. i've got your donanemab here for you... mike colley has alzheimer's disease, yet the 80—year—old feels incredibly fortunate. i'm one of the luckiest people you'll ever meet. just for this.

that's because he's been on the global trial of donanemab for two years. he's come with his son for his monthly infusion at this clinic in london. i seem to get more confident every day. and i'm sure this is going to be successful. they'll get all the rubbish off the top of my brain and i'll be back to normality. i'm very confident about that. i never thought that i would see my dad just so full of life again. you know, now we have hope and, two years ago, we didn't. and, you know, that'sjust an incredible difference. i'd like you to subtract seven from 100, _ and keep subtracting. seven from each answer until i tell you to stop. so what is 100 take away seven? 93. despite mike's optimism, donanemab is not a cure. his memory and ability to process information

are still impaired. 86... but full results of the trial show the drug slowed cognitive decline by about a third, enabling many patients to continue leading independent lives for longer. 60... he chuckles i've - forgotten already now. i've lost the plot, sorry. that's ok. in alzheimer's, a rogue protein called amyloid builds up around neurons, destroying connections. donanemab is an antibody which binds to amyloid. this prompts immune cells to attack and clear amyloid from the brain. so, lots of toxic . amyloid protein... you can see it clearly in these scans. this patient starts with a lot of amyloid — shown in green, yellow and red — but after six months on donanemab, most of the amyloid has been removed. this is really significant. i mean, this is one _ of the biggest breakthroughs, insomuch as this -

disease is a pandemic. it's getting more i and more common. and being able to both - remove the amyloid protein and demonstrate that that. correlates with the slowing, or hopefully steadying - of symptoms, is life—changing. so a moment of hope? a moment of enormous hope. this is fantastic. hello. are you ready to come through? yes. all right. donanemab could be licensed here within a year, butjanet north is hoping to get it sooner, as part of the next stage of trials. could you tell me what year it is? oh, dear. she sighs no. 2004, i was going to say, but it's 2020—something, isn't it? 2024? 0k... janet, who's 76, says alzheimer's means she no longer remembers how to use a computer or how to cook.

i can't make things nice. i can't cook as i want to cook. i have no timing ability, and that's crucial. erm, itjust drives me potty, because i can't do it. but before any patient gets donanemab, they have to have one of these — a pet scan, a specialised type of brain scan. the problem is, there aren't nearly enough scanners. currently, hardly any alzheimer's patient has one. there's another hurdle. donanemab has potentially serious side effects. it can cause swelling and bleeding in the brain, so patients will need to be aware of the risks and be carefully monitored. but despite safety concerns, there will be huge demand for this new drug, which mike will continue to receive as long as it helps him. after decades of failed trials, the era of alzheimer's

treatment is upon us. the first space tourists travelling on sir richard branson�*s virgin galactic will launch next month. among those on board will be a mother and daughter duo, plus an 80—year—old who bought his ticket nearly two decades ago. bbc�*s ellie price reports. the spaceship attached to a mothership... as bucket list dreams go getting into space is a difficult one. when i was two years old, just looking up in the skies, i was like, "how can i get there"? it turns out a raffle ticket will do it. keisha and anastasia from antigua will be the first mother and daughter to blast into orbit together. jon goodwin from newcastle—under—lyme, who's 80, has beaten the odds in another way. he's got parkinson's. i was pretty convinced that they were going to turn round to me and say,

"you're not able to go." but they have been fantastic — the fact that i can defy my parkinson's. three years ago, i climbed kilimanjaro and cycled down just to prove that it wasn't going to get me. and this is the same thing. an olympic canoeist in 1972, he knows a challenge. release, release, release. plane released. but despite this flashy promotional video, john remains pretty down to earth about his trip. even if he did pay $250,000 for a ticket 18 years ago. i think the opportunity to do something that's not been done before by many people at that price is a real bargain. the flight will lift off on august 8. ellie price, bbc news. a sweater with a complicated royal history is up for sale. it's the so—called �*black sheep jumper�* princess diana wore to a polo match in the summer of 1981, one month before

her marriage to then—prince charles. it set off a fury of specualaton over what message she might have tried to send. it is expected to sell for as much as $80,000 at auction later this summer. thanks for watching. stay with us here on bbc news hello. if you're wondering whether any of the heat that's currently affecting southern europe might head our way, well, the answer is a resounding no, but that is good news, i think, when you look at these temperatures. these temperatures which we recorded in the south of europe on monday, are very dangerous indeed. and this heat shows no real sign of letting up. now, we are stuck in a very different type of weather. the jet stream diving to the south of us that's keeping us away from this hot air, instead keeping us in something cooler, and with low pressure in charge, it is quite unsettled. this weather system pushing its way in from the west right now is going to bring some very heavy rain for some through

the day on tuesday. that rain through the morning, across parts of northern ireland, then swinging across the irish sea into wales, the north of england, the south of scotland, southwest scotland could be very wet for a time. bit of rain into the southwest of england. northern scotland seeing sunny spells and the odd sharp shower. the southeast of england should hold on to some hazy sunshine and some warmth, 23—24 degrees, but stuck under cloud and rain. you may well see temperatures no higher than 14—15 degrees. very wet for a time through the evening, particularly across parts of southern scotland. that rain then tries to pull away eastwards. i think cloud and some patchy rain may linger across southeast scotland and northeast england into the first part of wednesday. those are the starting temperatures for wednesday. and then this legacy of cloud still sticking around across parts of northern england, maybe southern scotland, down towards the east of england as well, with the odd spot of rain through wednesday morning. elsewhere, sunny spells and scattered showers. some of those could be on the heavy side. and temperatures of around 18 degrees there for belfast, 23 degrees the high in london.

forthursday, it's the sunshine and showers day. most of the showers are likely to be across the north and the east of the uk. not as many showers further west. and those temperatures again in a range between 16—22 degrees for most of us. so any big changes as we head towards the end of the week? well, not really. various weather systems, various areas of low pressure still featuring in the forecast. bit of uncertainty about where it might be wettest over the weekend, just how windy it's going to be, but certainly staying unsettled and relatively cool and no change in that story into the start of next week.

this is bbc news. this is bbc news. we'll have the headlines and all the main news stories for you at the top of the hour, for you at the top of the hour, straight after this programme. straight after this programme. yes, do you need to...?

take your jacket off.