we talked to so much about women's football, the lionesses are in a different place at the moment, three goals in the first half an hour before they managed to get the game only to lose 4— three so lots of questions for sarina wiegman to answer, being the manager. just eight months out from the euro defence, in the summer. elsewhere, scotland, northern ireland and wales were all playing and trying to join england at next summer's european championship. there were mixed results, asjo currie reports. a chaotic night for england showed a defensive frailty. it was a disastrous start, captain leah williamson gifting the ball away, millie bright put the brakes on but the referee said penalty. julie given striking an early blow. and

things went from bad to worse when kevin got another shot away and hannah hampton bingoalfloundered, hannah hampton bingoal floundered, germany hannah hampton bingoalfloundered, germany 2—0 up inside 11 minutes. and the carnage continued, hampton beaten again, germany in dreamland at wembley. european champions humbled. but hitting rock bottom ignited a fightback in the lionesses. finally. georgia stanway dispatching a penalty awarded for handball. no time to celebrate. she had work to do and just three minutes later the midfielder netted again to sign off her breath was first half. any hope of a comeback was snuffed out after the restart. another penalty with the same outcome. english defence all that seed, germany's wasn't much better, lucy bronze getting the final say on a night that will long in the memory. the england's preparations ahead of begin in dramatic fashion. that, well that will act as a wake—up call. meantime the other home nations are still trying to secure their place in switzerland. in hungary, scotland made hard work

of theirfirst in hungary, scotland made hard work of their first leg but came away with a 1—0 win thanks to martha thomas eventually smashing home her chance. northern ireland chris ketter i—i chance. northern ireland chris ketter 1—1 draw away to croatia, having dominated possession, struggle to find the net and looks like they were headed for defeat until this late own goal. but wales's hopes of reaching the first major women's tournament has been dealt a blow after they suffered a 2-1 dealt a blow after they suffered a 2—1 defeat to slovakia. having found themselves 2—0 down, theo morgan pulled one back late on to give themselves and hope to get of the heimlich next week. —— heimlich. —— home leg. jo currie, bbc news. in the premier league, nottingham forest's impressive start to the season continues after a 3—1 win at rivals leicester city — a result that moves them up to fifth place in the table for now. chris wood scoring twice for the visitors — that's seven goals this season for him — and maintains forest's unbeaten away start to the season. there are five more premier league games today. the champions manchester city are at home to a southampton side with just one point from their first

eight games this season. pep guardiola knows a win will take city top with liverpool away at arsenal tomorrow, but the city boss says nothing can be taken for granted. if you start to change your thoughts from the results, the players will notice. they know you are not a big believer. sooner or later, the results are about discovering after the champions league, i prefer to play against the teams inaudible on the table because you are focused on the table because you are focused on the best we can do is just watching the best we can do is just watching the table. after promotion last season, portsmouth continue to have a tough time of it in the championship after losing 2—1 at home to sheffield wednesday. they led at half—time but wednesday turned the game around in the second half with michael smith scoring a spectacular winner. it moves them up to 11th with portsmouth bottom of the league after 12 games. katie boulter�*s missed out on a place in the final of the japan open after being beaten in straight sets

by sofia kenin in tokyo in their semi this morning 6—4, 6—4. meanwhile, the men's british number one jack draper has a semifinal in vienna to look forward to later today — that's after he beat tomas machac of the czech republic to seal his place in the final four, where he'll play italy's lorenzo musetti later. three games in rugby union's premiership today, including both saracens and bath in action. a win for either could take them top of the table. bristol currently lead the way after beating northampton last night 31—23 at ashton gate. joe batley with bristol's fourth and final try. rugby league's autumn internationals get under way this weekend. tomorrow, england's men take on samoa. this afternoon, england's wheelchair side take on their great rivals france in a repeat of the 2022 world cup final. when you're always battling it out at the sharp end of competitions,

whether it is world cup for european championships or, like, test match series like this one, you inevitably get an affinity for each other and obviously, there are enemy at the end of the day and we want to get one over on them, but we wouldn't have got to the level we've got to without them pushing us all the way and i'm sure they'd say the same to so you know, we are a pether bring the best out of each other and i'm sure it will be the same on saturday. sure it will be the same on saturday-— sure it will be the same on saturda . ~ ., ., ., ., saturday. we look forward to that later today- _ saturday. we look forward to that later today. thank _ saturday. we look forward to that later today. thank you. _ time now for a special programme about the oxford—astrazeneca covid vaccine, which was credited with saving millions of lives during the pandemic. more than three billion doses of the jab were distributed around the world — not for profit — but in rare cases, the vaccine was also responsible for serious side effects. our medical editor fergus walsh has the latest. the astrazeneca covid vaccine played a key role in the pandemic. protecting millions in the uk

against serious infection. the a - roval against serious infection. the approval of — against serious infection. the approval of the _ against serious infection. tue: approval of the austro against serious infection. tte: approval of the austro astrazeneca vaccine, which is a fantastic achievement for british science —— oxford. achievement for british science -- oxford. �* ., ., , ., , oxford. but for the minority, it was the 'ab oxford. but for the minority, it was the jab that — oxford. but for the minority, it was the jab that caused _ oxford. but for the minority, it was the jab that caused devastating - the jab that caused devastating harm. t the jab that caused devastating harm. h, ., the jab that caused devastating harm. ., , ., ., the jab that caused devastating harm. ., ., , harm. i cannot stand, i cannot sit u, i harm. i cannot stand, i cannot sit up: i cannot— harm. i cannot stand, i cannot sit up, i cannot walk. _ harm. i cannot stand, i cannot sit up, i cannot walk. i— harm. i cannot stand, i cannot sit up, i cannot walk. i miss - harm. i cannot stand, i cannot sit up, i cannot walk. i miss the - harm. i cannot stand, i cannot sit up, i cannot walk. i miss the life | harm. i cannot stand, i cannot sit| up, i cannot walk. i miss the life i had before. up, i cannot walk. i miss the life i had before-— up, i cannot walk. i miss the life i had before. ., , ., , had before. the only way to proceed is i'm told roar. _ had before. the only way to proceed is i'm told roar. i _ had before. the only way to proceed is i'm told roar. i think— had before. the only way to proceed is i'm told roar. i think we - had before. the only way to proceed is i'm told roar. i think we thought l is i'm told roar. i think we thought that she _ is i'm told roar. i think we thought that she would be treated and then she would — that she would be treated and then she would get better and she would come _ she would get better and she would come home and that would be that. you are _ come home and that would be that. you are still— come home and that would be that. you are still waiting two years on? is the government scheme designed to support the vaccine injured fit for purpose? tt’s support the vaccine in'ured fit for --urose? fl ., support the vaccine in'ured fit for --urose? �*, ., ., , support the vaccine in'ured fit for --urose? v ., purpose? it's not really responsive to the level _ purpose? it's not really responsive to the level of _ purpose? it's not really responsive to the level of disability _ purpose? it's not really responsive to the level of disability that - to the level of disability that people are experiencing and it's certainly not changing over time as the cost of living rises. find certainly not changing over time as the cost of living rises.— the cost of living rises. and now, those left — the cost of living rises. and now, those left injured _ the cost of living rises. and now, those left injured or _ the cost of living rises. and now, those left injured or bereaved - the cost of living rises. and now, | those left injured or bereaved are fighting for a pay—out. it those left injured or bereaved are fighting for a pay-out.— those left injured or bereaved are fighting for a pay-out. it would not be necessary _ fighting for a pay-out. it would not be necessary to — fighting for a pay-out. it would not be necessary to bring _ fighting for a pay-out. it would not be necessary to bring any - fighting for a pay-out. it would not be necessary to bring any legal- be necessary to bring any legal action whatsoever if the vaccine

damage payment scheme was working properly. the covid pandemic pushed the nhs to the brink. ~ �* ., , ., , the brink. we've got three times as many critically _ the brink. we've got three times as many critically ill _ the brink. we've got three times as many critically ill patients _ the brink. we've got three times as many critically ill patients in - the brink. we've got three times as many critically ill patients in this i many critically ill patients in this hospital than we normally have. this hospital than we normally have. as the uk headed into its first winter with the virus, at the end of 2020, lives and livelihoods remained heavily restricted. but amidst the gloom, there is hope. the vaccine basis by giant astrazeneca. "tte: approval of the vaccine gloom, there is hope. the vaccine rollout begins. first pfizer. and rollout begins. first pfizer. and then, i'm going vaccine is approved, approval of _ the - then, i'm going vaccine is approved, developed at oxford university and developed at oxford university and manufactured on a not—for—profit manufactured on a not—for—profit basis by giant astrazeneca. the basis by giant astrazeneca. the a- roval basis by giant astrazeneca. the a- roval basis by giant astrazeneca. the

approval of _ basis by giant astrazeneca. the approval of the _ basis by giant astrazeneca. t'te: approval of the oscar basis by giant astrazeneca. tt2 approval of the oscar astrazeneca vaccine, which is a fantastic achievement for british science. tt achievement for british science. it is a great day, we very proud. achievement for british science. it| is a great day, we very proud. this is a great day, we very proud. this is a great day, we very proud. this is a really — is a great day, we very proud. this is a really significant moment in the fight — is a really significant moment in the fight this _ is a really significant moment in the fight this pandemic. - is a really significant moment in the fight this pandemic.- is a really significant moment in the fight this pandemic. adam finn has sent the fight this pandemic. adam finn has spent decades _ the fight this pandemic. adam finn has spent decades researching - has spent decades researching infectious diseases and immunisation. a professor of paediatrics, he was a member of the influential committee which advised the uk government on the rollout of covid vaccines. the the uk government on the rollout of covid vaccines.— the uk government on the rollout of covid vaccines. the protection these vaccines were — covid vaccines. the protection these vaccines were able _ covid vaccines. the protection these vaccines were able to _ covid vaccines. the protection these vaccines were able to deliver - vaccines were able to deliver rapidly, evenjust vaccines were able to deliver rapidly, even just after the first dose, really saved a lot of people's lives.

same spirit of gratitude and optimism from those receiving their jab. me included. thank you, bruce. you are welcome. bhd jab. me included. thank you, bruce. you are welcome.— you are welcome. and ultimately, it is science we — you are welcome. and ultimately, it is science we have _ you are welcome. and ultimately, it is science we have to _ you are welcome. and ultimately, it is science we have to thank- you are welcome. and ultimately, it is science we have to thank for- is science we have to thank for giving us this route out of the pandemic. giving us this route out of the pandemic-— giving us this route out of the . pandemic— it's pandemic. done? thank you. it's estimated _ pandemic. done? thank you. it's estimated that _ pandemic. done? thank you. it's estimated that about _ pandemic. done? thank you. it's estimated that about deaths - pandemic. done? thank you. it's| estimated that about deaths were prevented by the uk covid vaccination programme up to september 2021. vaccination programme up to september202i. but vaccination programme up to september 2021. but this film is not about the huge positives that covid vaccines brought. a story that has been told many times. rather, it is about the small minority left injured or bereaved by a rare side effect of the astrazeneca jab. blood clots, usually in the brain. irate clots, usually in the brain. we started clots, usually in the brain. 2 started seeing a cluster of these cases, not only in increase number but also occurring within a

relatively short time, usually the first dose, of astrazeneca vaccine. and so, the moment that that signal became recognised, it was clearly something out of the ordinary and numbers, even though they were very small, were far in excess of what we would have expected to see chance alone. this would have expected to see chance alone. a ,, , would have expected to see chance alone. a , . would have expected to see chance alone. as cases increased, this ex - ert alone. as cases increased, this expert in _ alone. as cases increased, this expert in blood _ alone. as cases increased, this expert in blood disorders - alone. as cases increased, this expert in blood disorders told i alone. as cases increased, this i expert in blood disorders told me doctors were facing an alarming possibility that the vaccine was responsible. t possibility that the vaccine was responsible-— responsible. i was extremely surprised _ responsible. i was extremely surprised about _ responsible. i was extremely surprised about the - responsible. i was extremely surprised about the link - responsible. i was extremely surprised about the link all i responsible. i was extremely i surprised about the link all the potential link between astrazeneca and this new thrombotic syndrome. it was not something any of us had envisaged. all of the patients that we initially identified were previously completely fit and well. they presented very suddenly with unidentified —— with what we identified as having a low platelet count, blood clots either in the brain or in the liver, primarily,

and deteriorated very, very quickly. platelets are tiny cells which stops blood loss by causing clots when you cut yourself. but low levels of platelets, combined with clots, meant these rare cases could be directly attributed to the astrazeneca vaccine. and were given a new medical term, viit, vaccine induced thrombocytopenia and induced arthrosis. before i have the vaccine, i was very independent, active woman. vaccine, i was very independent, active woman-— vaccine, i was very independent, activewoman. ., ., ., ., , active woman. doing half marathons and enjoying — active woman. doing half marathons and enjoying my _ active woman. doing half marathons and enjoying my life _ active woman. doing half marathons and enjoying my life and _ active woman. doing half marathons and enjoying my life and now, - active woman. doing half marathons and enjoying my life and now, i've . and enjoying my life and now, i've lost every bit of independence. i cannot even show it myself. jane wriule cannot even show it myself. jane wrigley had _ cannot even show it myself. jane wrigley had her— cannot even show it myself. jane wrigley had her first _ cannot even show it myself. jane wrigley had her first and only dose of the astrazeneca vaccine on the 16th of march 2021. the first

warning signs came two weeks later. i'd gone to bed with a headache, which is very, very severe headache. and then in the morning, i woke up and then, i really didn't feel very well. t and then, i really didn't feel very well. 2. , and then, i really didn't feel very well. , ., ., well. i called my daughter through because my _ well. i called my daughter through because my aunt _ well. i called my daughter through because my aunt kept _ well. i called my daughter through because my aunt kept falling - well. i called my daughter through because my aunt kept falling off. well. i called my daughter through l because my aunt kept falling off the bed and i said i don't feel very well so she called triple one and they sent an ambulance, didn't they? __my they sent an ambulance, didn't they? ——my arm. t they sent an ambulance, didn't they? --m arm. ., , �* , , --my arm. i wasn't here but they sent an ambulance. _ --my arm. i wasn't here but they sent an ambulance. i _ --my arm. i wasn't here but they sent an ambulance. i had - --my arm. i wasn't here but they sent an ambulance. i had gone i --my arm. i wasn't here but they| sent an ambulance. i had gone to work _ sent an ambulance. i had gone to work i_ sent an ambulance. i had gone to work i got— sent an ambulance. i had gone to work i got a _ sent an ambulance. i had gone to work. i got a call a little bit leter— work. i got a call a little bit later in— work. i got a call a little bit later in the day to say make