hmm, a deficiency is observed in the body, hence the main manifestations of which we have already discussed are slowness of movement , stiffness of movements, tremor, impaired gait. here, uh, as if the lack of this dopamine has already been found today. how can it be replenished. these are levodopa-containing drugs or in adobe - this is the precursor of dopamine through a series of chemical reactions, it turns into domino and into some kind of small one. unfortunately, the parts reach all the necessary structures, they are included in the work they need, so it’s precisely the lack of dopamine and the death of these cells of black substances. this is the main mechanism for the development of parkinson's disease . unfortunately, no drugs have yet been found that would help regulate the survival of these cells to stop their death. no such drugs are being developed all over the world and are being searched for. that is, it is a neuroprotective therapy to force the cells to continue to produce dopamine. unfortunately, this. the selection of medications

for the treatment of parkinson's disease depends on the stage of the disease. at the very beginning of the development of the disease, doctors use drugs, which stimulate the synthesis of dopamine, a neurotransmitter, the amount of which decreases with progression, and drugs that stop the breakdown of this neurotransmitter, preventing its reuptake, these drugs are in many ways similar to antidepressants. at the third of the five stages of the development of the disease, a drug with the active substance levodopa is prescribed; if the disease debuted at the age of over 70 years, then, as a rule, a drug based on lyubopa was prescribed immediately, went to bed twice. in the center here are all attractive indications for surgery. at me were positive. so vladimir vladimirovich agreed to have an operation and did and did on october 15 this year, so what changes occurred in the body, how was it implanted? well, you know, three

bitches passed. the number of tablets decreased by half, because i took up to 6 tablets per day of levadopa. yes, now i take three pills, here. well, somehow more, although she has not sat behind the wheel yet. unfortunately the car is something that i really like to really love to get along with the car, but life has become easier. their work is not easy, we work round-the-clock mode, that is, completely disconnected from the production process from work, probably, somewhere it does not work out on the flight. this means that it is now under the responsibility of the airline. every day they have to face different tasks, and

sometimes very non-standard ones. they come up with the most unusual things to take on a trip. well, probably the most unusual thing that happened was a dewar vessel with liquid nitrogen, which was smoking right at the airport, all the characters are completely different, which unites them with a desire. to achieve the best result we export enterprise. uh, 85% of our products come from us, and only 15% is in our domestic market for passenger service and our desire to provide a good service. uh, transfer passengers to maximum safety and comfort. watch project one day on our tv channel. we always cook delicious food from the heart. well, of course, you know what we will cook today. i don't just know what to cook. well, i know

how we will cook, we will share recipes for dishes that are a must. with all your family. today we will have a fish on the table for tomorrow. we have salmon and in addition to fish we will have chips, and this recipe is easy to prepare and i think it will turn out very tasty. stylish male hands are definitely needed here. in the mouth, we will analyze all the subtleties of their preparation cabbage on a steak, you need to cut the back side of the stalk. so that we cut into steaks to the stalk, and throw out the stalk and tell. how to choose vegetables and fruits correctly signs of good apples fruits are not damaged and have no traces of parasites on apples there are no dark spots the aroma is felt even through the skin tv channel.

you are watching the medical secrets program, plus we at the republican scientific and practical center of neurology and neurosurgery are trying to uncover the secrets of parkinson's disease, the disease is more than mysterious, therefore, to reveal all the secrets. we are unlikely to succeed 10 years ago. we have already filmed in the operating clinic doctor. vladimir alekseevets, performed a unique operation, the patients of which this help was vital. we are two steps away from the operating table and we are talking about that. that the victory over parkinson's disease, as well over any other disease is a rather complicated thing to the end in a number of cases, especially in such complex diseases and especially in diseases of the brain, revealing a secret does not mean significance and that is why

such methods as implantation, e-stimulators of chronic stimulation of deep structures have become widespread, after all, in fact, well, roughly speaking theoretically, if a person lost a leg, well, at least in some very complex experiments, they managed to grow new ones on mammals limbs. and, probably, deeply theoretically in some global scientific plan, it is possible for a person to grow. yes, i believe in it, but how would it be easier to manufacture. how much money will be spent on this. and when it will be better, probably, someday it will be more painful, it is now, and therefore the focus has shifted not to the treatment of the disease itself, but to the correction of some mechanisms. moreover, in some cases the mechanisms are genetic. yes, we still don't know. until the end here are the subtleties in these arrangements. yes focus shifted. ok then. we can't do anything about the cause. damn, let's suppress the symptoms in europe, this term is called neuroprosthetics. that is, when certain, uh,

neurological functions of the body are prosthetized, yes, uh, that is. generally. in general, yes, the treatment is symptomatic and today dr. alekseyvets. he says exactly the same, the treatment is symptomatic, but for sick people. this is what is needed today and now progress in treatment and disease is outlined, if we are talking about progress, if we are talking about the future, we can do we expect soon? to improve our knowledge to increase our knowledge to a volume that gives a chance for a normal, adequate, full-fledged social life. well , if here, again, m-m normally adequate full-fledged life. in general, already now we are able to display parkinson's disease symptoms of parkinson's disease to suppress sufficiently that a number of patients occurs. in general, uh, quite a normal life and social domestic adaptation. we have a case where patients even return to work. here, speaking more

globally, that is, there is scientific and technological progress in this area, that is, certain outlines in cell therapy, and in restoring the function of the substance of the game. this is exactly why parkinson's disease arises and dies in any way, which is a black substance that produces endogenous dofamyal cells, which are distributed by auction to various parts of the brain. and when fomin is not enough and signs of parkinson's disease appear, basically now, well, we are talking, uh, about cellular therapy, or there is still such a variant of vector therapy, and while these methods are not widely used in patients with parkinson's disease, there are only two ways of medication and surgery for the latter is called neuroprosthetics or implantation of a nerve stimulator and lasts

almost 6 hours. first, computer planning is carried out, in which the neurosurgeon creates a virtual map , outlines the coordinates of the upcoming interventions , selects the target zones of influence, as well as the entry points to them. the next step is the installation. a special style of toxic apparatus is formed on the head with a structure that is attached to a surgical instrument and with its help the electrodes are immersed in the brain, then. a neurostimulator is implanted in the carnivorous area, a small, long-lasting, working computer. its first switching on and programming is carried out only 2 weeks after the operation. at the same time, experts evaluate both the results achieved and side effects in our heroine, the question of whether or not to do the operation was not. it was the only possible way to return. although would be part of the quality of life that the disease took away. it happened in the twelfth year. my husband got sick. that can be seen on a

nervous basis, because there is no other explanation . my right arm started shaking. right leg. i went to many doctors , went to russia and ukraine, and then, well, there were circumstances that i had to turn here in belarus, so i came here for a consultation. well, they immediately sent me for a consultation, because parkinson’s for my then age. they are very characteristically 46 years old. not no age for parkinson's disease came here for a consultation. uh, they supervised me. and when there was not enough drugs or in hell, and they put me in for an operation. and how threatening you didn't look. this is an operation of a fundamentally different treatment, alas, so far science has not yet come up with. by the way, after such an operation, the patient is approximately. a month later, he comes for re-programming and then shows every six to 12 months. no additional rehab. after surgery needs. no, batteries. you, probably, stimulant me. as needed, the

average is not enough for 4-5 years. the only thing to be afraid of, those who support the intervention window, is the electromagnetic field, and it is not surprising to see how this intervention looks cosmically, so that you feel unusual. crawling goosebumps no necessarily turned off, and now i let go, and there were no such sensations in my hand that, like, my hand was pulled only my cheek. yes , a huge number of such interventions have been made in the world today. this operation can reduce the severity of the main symptoms. diseases. trembling, stiffness and slowness of movements significantly reduces the doses taken by patients of drugs in the postoperative period. unfortunately, electrical stimulation is not always effective in dealing with gait disturbance, stiffness and

unsteadiness. after operation. sometimes the forces of the disorder can be aggravated and the doctors offer patients such an operation on a deployed, by the way, illness, when the prospects for drug therapy worsen, in general, life changes completely when you get sick already. for example, i can't enter a car now. however, that's 2 years ago. i was free to drive. so i can't be in a big company of people me. well, as if i'm scared, it will just lick me and that's it. i can't do something well, although i serve myself i still have such a stage of the disease, when i serve myself, thank god and god forbid that the doctors stop this period. that's what i can do to the end to be independent. well, i would like to. that is why i went for this operation, returning to the prospects of treating diseases, using cells and my own fibroblasts. skin a very promising direction in 2018.

in japan, the first such operation was performed on a sixty-year-old patient with sleep disease implanted with neurons that were created from his own skin cells, it is too early to talk about the benefits of this operation . the duration of observation is short, but the world does not stand still. it is quite possible that these cells will also influence the course of the disease itself, no matter how it is, any method of treatment relies on the cause of the disease, to be sure. why disease occurs parkinson's is impossible, but it is already clear today that it still has a genetic condition, if you are that it hurts protten is genetically determined, so death is programmed, then the so -called vector is introduced, that is, uh, a genetically modified virus. introducing it into the brain already corrects this genetic damage, if such a certain work, but i must say that both e-vector therapy and

cell therapy. they still, in general, have not left the laboratory for wide clinical practice today. we can to talk about high-quality drug therapy and surgery with the help of neuroimplants, that is, with the help of implantation of electrodes, the implantation of an unreality simulator in the brain, returning to the causes of the disease, heredity, apparently, really plays an important role. in some cases, 10-15% of people. with parkin's disease. if there is a close relative with the same disease, it is most likely that the causes of the disease are genetic features if parkinson's disease develops in a person before 50 years of age. there are also some possible risk factors from the external environment most evidence that parkinson's disease is more common in people who consume large amounts of dairy products well. and in people who have been exposed to pesticides, it's not about poorly washed apples, but more serious exposure. our heroine. he sees the cause of the development of his

illness, the next question. why am i why not someone else? why are they someone else? so it means that it was not written in fate. i don't know. although the doctors first asked me if i have such a genetic predisposition, did anyone in my family get sick, but, unfortunately, i don’t know my grandfathers at all, and my mother and father didn’t get sick, so genetics can probably be attributed, but i think it’s just stress like that influenced me, each person is unique in his own way, so it all happened to me, probably due to stress. stress is associated to a lesser extent with the development of parkinson's disease, but given the fact that the exact cause of the disease has not been identified , no one will undertake to deny this connection either. by the way, curious fact parkinson's disease is less commonly diagnosed in women. smokers, drinkers with caffeine and those who take non-steroidal anti- inflammatory drugs. we have

very little time left, and as usual, i asked our heroes a question. how not to become a victim of parkinson's disease that for this we can do right now the fact that a person gets sick, if somewhere in his family there are patients with parkinson's disease, of course , more and possibly such patients, but they usually take care of their sick relatives, as the disease manifests itself. they are perhaps they are more afraid and listen to themselves more to ordinary people. it is difficult to give some special recommendations to give the right regime of work and rest, to find time to relax on the weekends and go on vacation. it's important to take a break from your work. well, the most important thing, as in parkinson's disease and in many of our neurodegenerative diseases, when cognitive functions decrease and over time people understand this very clearly, it has already been formed that physical activity plays an important role. no matter how smart a person was not, and how would he advance his

scientific activity, if he were not physically, er, in any way. uh, even if the outdoors lack of physical activity, his cognitive reserve will decline cognitive reserve to maintain a multi-activity. not only your interest, for example, learn foreign languages ​​at any age. uh, there you do homework with your grandchildren. and that will be the happiness of the surgeon. i had a more specific question. which of the methods of treatment is the future of the future the future is behind them wallpaper here is not, at the present time. i've discussed the perspective, let's say, well, it's still clear uh, vector therapy cell therapy is somehow for example, if we're talking about cell there, how these cells will be delivered there are options. uh, when modified cells. uh, the stems are surgically delivered with a stereo taxus. here are some others, that is,

perhaps it will be a cellular meal using surgical techniques. it's hard to talk about it now, but in any case, it's like a multifactorial the disease is more logical, then it cannot be said that the future belongs to the surgeon or to hurry, most likely, somewhere the truth will be somewhere in the middle, and while scientists in russia are still searching. in vei it will not be found today, so tomorrow, believe, that something will change and something, of course, i believe in no other way. we must believe, we must hope that they will still find some kind of panacea in order to cure this disease, at least to stop it, doctors must believe on this good note, we will pause. we wish good luck to you too. i think that your optimism there is vice. yes, so to speak , perceive life more optimistic than negative. yes, i would like to wish absolutely

optimism in this life parkinson - yes. this is a terrible terrible person, it turns out in general, well, yes, although he is underestimated. i think that now there is no such correct adequate assessment. no, i don't think so either. probably. bye bye bye yes hope it happens.

this is one of the waltzes they once had a period, so he wrote such music. it should be there must be a creative dimension of some completely different dimension. that is, we will not see it. we won't read it, but it creates a i don't know mood.