hello, and i answered no to this question, since am, the main unit of length in si and is a meter is an intellectually entertaining show that motivates you to stretch your brain elena you clicked you clicked answer quickly. wait. i do not know you can not answer the wrong answers - it's minus five, it's okay. i just remind you, watch on belarus 24 tv channel.

the scientific community first heard about this concept relatively recently only in the nineties of the last century. it was then that american

diagnostician. leo golub suggested using a patient -centered approach in the field of diagnosis and treatment of diseases. and now, 30 years later, doctors all over the world are literally on the verge of a real revolution of transition to medicine of a new type and it is called personalized or otherwise personified in the air of science addiction. my name is ekaterina beretskaya. hello. and today we will figure it out. why the future in the field of medicine? so it’s definitely much closer than it seems to us, see the program for an individual approach patient and not only explore the main features of personalized medicine. change dna for health as our geneticists help physicians improve standard therapies and the pill is not for everyone with an emphasis on the personification of pharmacology. the development of personalized medicine is one of the priority areas of our science, what it is in

general and what kind of personalized medicine should be, my colleagues have already asked the director of the institute of physiology of the academy of sciences, it is there that most of the issues of interest are being solved now. us today topic. well, regarding issues related to personalized medical care, we, as scientific organizations, are most of all in this regard, respectively, working with cells. that is, we have a laboratory of cellular technologies, which has e-boxes that have different cultures of e-cells, where it is possible to achieve the effectiveness of the treatment of not only such extensive e-oncological diseases of such cells. we have data in our bank, but from such interesting directions, given that for the institute largely stands up to the clinic. we have learned how to print some variants of cells on a bioprinter and conduct selective tests of already

printed cells not on the living organism itself, and you will have time for certain ones in this regard, because the primary models that we did in 18-19. push, it's not easy. uh, monolayer 3d printers. model of his twenty-first year. we already have 4d printers that make multilayer cell combinations in real time. and this culture and multi-layered it must support your life activity. there are special solutions there that do not allow these cells to lose their viability, and they do not stop dividing and washing with such multilayer cell cultures. we are no longer only dealing with medicines, but also testing some cosmetic products less. uh, some lab animals involved, and more are already involved. yes, the culture of clients in order to move this or that approach for the treatment of some external defects. in general, of course,

infected medicines are the very future, because even the aspirin preparations that some are prescribed. sensitive, so even there special adf aspitest tests are used, which allows you to evaluate the aggregation ability of platelets. and in general, what kind of anti-aggregate, after all, cells react to this, because people over 50 years old who receive, er, after sixty even more aspirin-like drugs, so as not to rush into some complications, in principle. the most common gastric intestinal these must of course be evaluated for specificity. we are doing a p450 fear study in order to evaluate yes, the effectiveness of this chromium quotes on the metabolism of incoming drugs, in addition, the ocean is huge after the epiphany that some treatments,

especially oncological disease. and there are going on, based on the legal code of a particular excellent cool cell, a very important genetics of the genetics of red, but diseases and genetics of patients, so, of course, all cases are difficult, consistent with traditional treatment regimens. they just lie in the field of genetic coding, oncology, in general, or the treatment of any disease is impossible without a preliminary genetic academy, but in some cases, of course, we cannot use such methods for everyone today . enters force or clinical experience intuition? oh

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at home, lie on the sofa, or you can explore our beautiful belarus every week, we lay new routes in the corners of our country, however, centuries-old trees remained not only in helmets. they can be found even today, this particular oak is already 400 years old, and to wrap around its trunk. it takes about four adults, we show historical monuments cultural entertainment alexandra vasilyevich will be with you now. we will conduct a master class in pottery ; as a true fan of potatoes, i ordered pancakes for myself. look in the program the route is built. on tv channel belarus 24

we will continue to study the topic of personalized medicine in the studio with our guest egor hello egor vladimirovich lemeshko head of a multidisciplinary diagnostic laboratory institute of physiology of the national academy of sciences of belarus candidate of medical sciences area of ​​scientific interests instrumental diagnostics medicine telemedicine technologies, legal support of health care cardiology therapy general medical practice human physiology such in general, personalized medicine. then. let's ask you. what is happening in medicine now? what is the name of the one that is still a priority all over the world, including in our state, today's medicine is responsible

the principles of the four paragraphs. yes. this is a forecast. this is a warning. this is exactly the same personalized medicine and partnership, if you analyze each principle, then the forecast, this is mine, we predict accordingly. state development. health, the patient has one of the measures - this is for example. the same vaccinations everyone knows what they are, but also other preventive measures that yes, prevent the development of complications of the state, health, personification. here is what it is about. you just said the theme of our today's program. the point is that we do not treat diseases, but a person was still said by mudrov, somewhere about three centuries ago, then they already came to this term. and today, such a state is being developed as much as possible, when we treat a person with his characteristics. eh, taking into account these features in the first place. this is about psychological characteristics. everyone, in general, has his own type

of personality, his own peculiarities, his reaction to certain stimuli, and so on and the second moment. if a person is exposed to all kinds of microorganisms. any other external irritants. perhaps, some violations on the part of his function already, which he has. all this will cause certain diseases, and the body owes this to five and the first one reacts unconditionally to the autonomic nervous system, and these are the features, how this system reacts in someone, what features of the mental state it has. all this must be taken into account in order for the treatment to be as correct as possible. not to mention the fact that yes, today we have protocols. we all know about them, and they also have certain advantages. doctors treat first of all unconditionally on them. but if the situation calls for it, then there are mechanisms by which the treatment can be refined, maybe something will change dramatically with the advent of personalized or personified differently called medicine. here is what was, what

is, and what will be. here you can. maybe there are some basic criteria about what is there, probably some kind of transitional moment. we have always paid attention to the individual patient, but the protocols set the framework, if possible. will appear, she will most likely appear. uh, when are we going to treat the nepos? here is one on one with the patient and we will take into account all his features. it after all depends not only on the doctor. it depends a lot on the organization. how organized is such a personalized approach. to what extent such conditions are created so that a doctor, for example, can directly pay attention to a particular patient. but this is impossible. we have many patients, but there is only one doctor, so we have to look for some compromises. well, and accordingly we have what we have, as it were, but let's go all the same in the direction of personification of the maximum consideration of individual moments. and what happened before there was less knowledge, respectively, they treated what they understood what they could before, there was

certainly less burden on the doctor. this is also due to a number of factors, and not only because the population there is growing every day, they began to live longer, and there are a lot, but a lot of factors, yes, which also need to be taken into account, and time leaves us no choice. we can't stand still once we stay put. some time is immediately behind. here it is necessary to go forward and keep up and overtake somewhere. this life is such a basis for personalized medicine, according to experts , molecular genetic research will become , including at our institute of genetics and cytology , such are already being transported. let's see the plot. the genetics of a person decides what kind of eyes he will have, what color hair, type of physique, and most diseases are also laid down at birth, genetic doctors call them hereditary studies of these particular pathologies. at

institute of genetics of the national academy of sciences of belarus, if scientists manage to find drugs that meet the individual characteristics of a person, medicine will reach a new level. we are engaged in, if we are talking about science about scientific research, this is the selection of some specific targets for the treatment of oncological diseases, and the second direction is, uh, individual sensitivity to drugs , the same drug, if we are talking, let's say about the treatment of cardiovascular vascular pathology. these are bisoprolls, such as apparatuses, which lower blood pressure. uh, they can use at a dosage of 0.25 mg, then 50 mg and that 's it. it also depends and is determined by the genetic characteristics of metabolism. here are the drugs that researchers are also studying the sensitivity to the chosen treatment. there are results of the treatment strategy or it still needs to be changed. joint research with the institute of

psychiatry, which allows you to choose the right antidepressants for the treatment of various neurological diseases. e, and. hey, probably one of those too. here are some interesting developments - the use of a genetic test in the selection of drugs for the treatment of viral hepatitis c. these drugs are very expensive. that is, they cost a few to this court or thousands of dollars there, and these drugs are prescribed to the patient free of charge, but there are several drugs and 25% may be insensitive to a particular drug and with the help of a genetic test. you can determine the non -responsiveness of the patient to this treatment and replace. e, respectively, the drug. naturally, no pills and doctors working towards personalized medicine is constantly focusing on this, they cannot help if the patient does not change his lifestyle, and doctors, starting from genetic data, kind of direct their wards to people to correct the lifestyle of nutrition,

because it is clear that we all need to be with you physically active to eat right, but most often a person does not think about it , when some problems already appear. and that's it development of personalized medicine using all kinds of tests. it's also genetic. this chemical e, allows a person to correctly adjust his lifestyle. in general, do not put him on the fact that he must change his lifestyle and carry out disease prevention. genetic testing, without which individual medicine cannot do, has been passed by 4,000 belarusians at the institute. the most private clients of the investigators are women who have encountered problems when planning a pregnancy. predicting the risks of developing multifactorial diseases is primarily miscarriage when using this test allows women who have problems with

our pregnancy to carry out the correct treatment during pregnancy and women give birth to a child. well, that is, this is one of these areas, and the second direction, about two years ago, we started new research. these are various pathologies of the kidneys in children, and, first of all, the type of pathology of the kidneys associated with the close development of various syndromes. many studies that literally 10 years ago seemed like science fiction are already on stream, at the institute of genetics and cytology we belarus however, a lot is still ahead for scientists are confident that the future of medicine begins today in this show to athletes. we'll have to relax the muscles and strain the brain. what

is the abbreviation for international football federation? alexander is fifa fifa of course my friends what a surprise? you believe in yourself today, confident in your sports knowledge. i'm sure intellectually entertaining project. heading is very fun and fervent, because we, in principle, all liberated people, went. watch on tv channel belarus 24. for delivery export cargoes in belarus under the sanctions rebuilds logistics and rolls out new routes included ports of the northwestern region of russia as well as port capacity and the black and azov seas quickly. it is also a new logistics for the delivery of domestic goods to china by rail and road, the government of belarus has approved forecast

indicators for 23 years. these are approximate guidelines for socio-economic development and a draft budget. achieve the main goals. next year, belarusians' income growth, while keeping prices down. from skachkov, two drugs for the treatment of oncology are at the final stage of development at the national academy of sciences of belarus, this is part of the process of import substitution of information optics. the first drug, completely created by belarusian scientists, completed clinical trials this summer. watch the program of events on thursdays on our tv channel. on the air of science addiction, we continue to understand personalized medicine and see further new ways of diagnosing monitoring, how informatization will help build a new type of medicine save millions. why personalized

medicine is profitable and what new generation drugs are being developed at the scientific and practical center of oncology and medical radiology you will find out very soon. yegor a at the institute of physiology what research is being done in the direction of personalized medicine? after all, i know that this is one of the key scientific institutions. that's it for this topic. in the structure of the academy of sciences, the institute of physiology is engaged in the biomedical direction. this is the main institution of scientific and e, with regard to direct medicine. without let 's say biological moments, we are developing a computerized system for monitoring the physical state of the patient's location. this system. she is completely personal. that is, each patient has an inserted medical device that registers his physiological parameters in real time, transmits to e, a remote workplace, in turn, a doctor, wherever he is, he can

receive this information, if it is alarming some parameters, this allows you to react in time, and not delay the time until the next appointment. this is just a timely response. it may be simpler than what might follow later, because time has not yet been lost. you can, for example, sit down somewhere, somewhere in time, take a pill that corresponds to some other manipulation, and everything will be fine. this is up to the fact that an ambulance brigade will be called to this place where the person is located . he will be given his time, urgent medical assistance, it is not always possible for a patient to notice such changes in his body. sometimes even life-threatening, and our system is aimed at detecting such things in time and responding to them. now. let's talk about medicines, because many people think that medicine is personalized. this means that

aspirin citramone, which helped everyone, will disappear, and everyone will have their own pill, so the question arises. where are so many? will be and how it will be at all, but in fact in pharmacology yes, the emphasis is also on perstnification, but this is a different situation, i understand correctly, just such a universal pill for a particular patient is very unlikely that we will come to this, maybe someday, but so far it is even very difficult to predict. and in general, uh, somehow imagine how, uh, real, uh, of course , they will develop medical preparations, because the same microorganisms do not stand still. they also improve, too, they have protective mechanisms. it's all necessary to study and accordingly develop new drugs, and they will certainly be made and used in practical public health. while the development of drugs . it will probably be like this, as

we will see it now, in order to have time to overcome the obstacles that we have. in general, in the life of some such universal tablets. well. so far, it is not possible to imagine in general such that research in the direction of personification of pharmacology is already being conducted in the npc, oncology and radiology. i suggest see the plot. previously, it was believed that all malignant tumors have approximately the same components. that is why they tell on the night at the practical center of oncology, radiology and treatment regimens, in fact, were the same. today, the doctor knows the molecular biological characteristics of all people are different, and this is before doctors scientists put a new the task is to create a drug that takes into account the features of tumor development at the genetic level, the tumor is a unique

genetic level, which directly affects on the effectiveness of therapy and on the aggressiveness of her behavior. these characteristics can change during treatment, therefore, initially effective chemotherapy regimens, and may turn out to be ineffective as the disease progresses, a personalized approach does not contradict conventional therapy regimens, but complements them and makes it more effective . physically targeting molecular solutions drugs, therefore not called target-directed or targeted drugs; torgy drugs act more selective. the main thing is to find molecular targets in the tumor, genetic testing copes with this task. the official efficacy of targeted drugs is based on molecular genetic testing. currently. uh, the entire spectrum of molecular genetic research for the selection of targeted therapy for oncological patients, and in the republic the republican

molecular kinetic laboratory is carried out, well-developed logistics allow us to concentrate the issue of prescribing this type of therapy with subsequent genetic testing is being considered, and the methods of genetic testing are quite diverse; the main ones are polymerase chain reaction, molecular sequencing, institutionalization, and other methods. these are very time-consuming methods that also require highly qualified specialists, which makes it just the same expediency to concentrate all research in one laboratory. another example of the treatment of oncological neoplasms in personalized medicine. this is a cell therapy from the name it is already clear that doctors take cells or tissues of the person himself in one of the directions associated with dendritic cells. they regulate the body's immune response in response to a tumor. and