what difference does the little ones also need ? well, today their dream will come true, respectively. today, the smell will already be put in the apartment. well, uh, artificial spruce, but still it is artificial, and the holiday is a real holiday, not artificial, not invented, the cost of new year trees. the most advantageous offer will vary from nurseries and on clearings in the regions, centers and cities, a christmas tree can be purchased from 15 rubles. and do not miss today the factors that will swirl the audience of the hebrew mahdiscotheques of youth in the columns of millions of televisions in the country, the hits of the nineties and zero , precisely those who continue to fight for a place under the spotlights of show business. now on your screens i will remind you that in the teams the neighboring seryogi already have two finalists. without changes. today we will hear from the wards of ruslan akhmal and olga buzova whose life on the project will be cut short today or will the viewers be allowed to

vote live on the air? a must-see for every participant your support some kind of melody i have everything until a meeting at 19:00. in our program, the most active schoolchildren from all over belarus, alexandra, i answered option b in the fourth, since 5 meet, 1254 is what 25. i know that the middle ages are divided into three periods - this is the early middle and later, so i answered. yes, they will find answers to all questions, the musical time is three times, two, three, to be honest, i answered no, because i am more inclined in this they are ready to surprise and win with two letters to do, and because here

there is a word inadvertently entertainment show better understand what to do in real life. i will explain the author of the project propaganda in detail consider widely. discussed topics analyzes the facts , gives arguments and refutes rumors, any important decision at the state level should have a clear goal, why we are doing this, and the end result should be better for people. my name is igor tur. it was my propaganda watch the new releases on belarus 24 tv channel.

choking with a leather word for all manifestations in a person creatively the most marvelous and suitable respect. it is books in books that live in the past, reports to different people. everything that a man trunk hawked on the sides of books to be the son of charisma, a person is experiencing from where the reeling bringing together the generation appreciate bypassing our dry belarus

siberian ulcer scabies rabies hepatitis diabetes mellitus all these diseases can still affect animals and our pets. and speaking with the language of animal specialists agricultural, but the main enemy remains a viral infection, which our veterinarians successfully fight only as in everything. first, the work is carried out by scientists, the virus is isolated, grown, studied, and then vaccines are created. however, let's not get ahead of ourselves and start to understand the topic in order. my name is ekaterina

beretskaya. hello. today in the new company. we will study the recipes of modern aibolites. don't miss the next half an hour. recombinant vector and dna vaccines new generation of vaccines for animals so that the bees do not get sick. what drugs scientists create for insects and solve the issue on the spot, how scientists save animals on farms in the program very soon. the institute of experimental veterinary medicine of the academy of sciences of belarus was established back in the twenties of the last century, and in the past, present and future, of course, my colleagues asked all those involved right at the solemn event dedicated to the centennial anniversary of the institute. for a whole

century, the institute of experimental veterinary medicine in belarus has been developing new methods for diagnosing and treatment of animal diseases. the institute of experimental veterinary medicine named after vasilevsky is a fairly significant scientific institution of the enterprise for a long period of time has been quite effectively developing the production of veterinary preparations, sera vaccines in some other areas, and they are constantly improving and interacting with our universities. first of all, local veterinary preparations are being developed and practically ensure the biological safety of our country. vaccines are sold abroad for various diseases we produce on an industrial scale, for example, the countries of central asia buy. and as soon as there is a new virus that infects

animals. our scientists are trying to find a new way to protect a vaccine or antidote. questions appeared, like uh new topical infections. it's, uh, african swine fever, it's supra-bovine dermatitis . uh, other infections. in particular, there are problems now with the 8th pathogenic influenza in the bird world. this is a disease that, in particular, is transmitted to humans and exists the danger of infecting people, so all these problems at our institute are naturally studied and we are working on these problems. plus. uh, we are doing some fundamental research for the future. here in particular. right there in our department. uh, new promising drugs that will be directed to the treatment of exactly the place that is sick, that is, pointwise they do not harm the entire

body of the animal. and this is a real breakthrough in veterinary medicine. dmitry sergeevich borisovets, head of the department of viral infections, institute of experimental veterinarians of the national academy of sciences of belarus candidate of veterinary sciences associate professor. i understand correctly that this is the same collection of deadly viruses in order to make it convenient for you to find these viruses in our animals. yes, absolutely everything to work. yes, of course at work. now i know you are creating a new

generation. please tell us about combined vector and even dna vaccines, what is it for, what is the department of viral infections of the institute of experimental veterinary medicine. for over 50 years. e working on the development of vaccines for veterinary medicine during this time, more than 80 different drugs have been created for animals, the technology that is used to create these prices. this is classic technology. that is, when we isolate a viral pathogen, we accumulate it on the cell culture, and then inactivate it, if you are a killed vaccine, it further introduces auxiliary components to form the final product, but naturally science does not stand still and new directions are developing, including for technologies. genetic engineering, we are also moving in the same direction, and in this regard, we are also developing the development of new generation vaccines, this is a recombinant vaccine, a vector vaccine, a dna rna vaccine, in this regard, we work

closely with the institute of biophysics and cell engineering of the national academy of sciences of belarus and , the main two directions. this is the development of vector vaccines - this is a vaccine that is being developed against viruses that are difficult to accumulate and difficult to culture. in particular. it's a virus respiratory syncytial infections and the second direction is a marker vaccine, when a specific marker. we insert a virus into the genome and such vaccines allow us to distinguish the vaccinated animal. here are those who have been ill, this is dna yes, but no, this is not a dna vaccine. this is a marker vaccine, they are being developed. mainly for diseases such as infectious rhinotracheitis, classical plague, swine fever, travel sickness virus. as for the dna of vaccines, i would like to note that not always from all technologies that work in medicine, they acceptable for veterinary use. that is, for example, as the covid-19 pandemic showed, the developed dna vaccine should be stored under conditions e, at -80 °. that is, the availability of specialized

equipment is required, that is, to supply our livestock enterprises with such equipment. quite problematic, therefore, given these features of the storage of this vaccine. there are a lot of difficulties here, okay. we haven't yet explained what vaccine recommendations are, a recombinant vaccine is when we cut out part of the nucleic acid of the virus, which is responsible for the production of specific proteins, immobino. and this area. we embed in some kind of viral vector. that is, as a rule, it is a safe virus that does not cause disease in animals, but it is a carrier of nucleic acid that embeds into the cell and thus provides a whole cascade of immunological reactions that contribute to the development. relevant immune response know that wild boar pigs found a new disease hepatitis. e. in our country it is fixed and worth should we be afraid of people, we detected cases of hepatitis during the period of the afghan war, cases

of illness of our military personnel were noted and hepatitis was diagnosed. and later, in 1981, academicians balayan was isolated from the virus from a soldier and self-infected , as a result of which he became the discoverer of this virus. and in principle it was believed that this disease was viral hepatitis. e. it is more typical for climate countries when using, for example, poor-quality water. subsequently, in 2003 it was it has been established that this disease can be transmitted from animal to person, namely, when using thermally poorly processed meat and liver from wild boars from domestic pigs. and this deer and was subsequently established. what exactly is the use of termi. and poorly processed meat is one of the causes of this disease can be prevented in animals here is the story. i know that you are actually working on the development of 2016 merphylaxis, and we are participating in an international project within the framework of the union

states in the implementation of this project, we have developed diagnostic t-systems for diagnostics for the purpose of monitoring - this is one of the tasks in the enzyme immunoassay of a polymet of a different chain reaction. there was also development. ah, systems. uh, preventive measures - this also applies to agricultural medicine, that is, for humans. this is more about personal hygiene. this is eating well thermally processed meat and liver. and also for example, if a person travels abroad it is recommended to use bottled water, as far as agriculture is concerned, but this is to a greater extent compliance with safety rules on farms, and timely cleaning and disposal of manure, as well as disinfection and quarantine of animals when they enter the farm. how about a virus. uh, in an animal you find. well, as i understand it, here are these test systems. yes, some, well, just again, an animal, you won’t take it to the

veterinarian to find out, and he won’t say there, something hurts me. look yes definitely a feature this disease lies in the fact that pigs, as a rule, are ill with asymptomatic and it is very difficult to detect clinical e, the signs of this disease are very difficult ; which will allow laboratory conditions to determine e, diseased animals, as well as after the infection has been recovered. that's just in the laboratory of your institute. my colleagues have gone. let's let's see what they saw there. 16 best teams and 48 favorites from all over the country, what will win strong nerves or emotions? no one here knows

what will happen in the next minute. this makes the four elements even more interesting, with which the participants must cope. i like the element of air and flight. in general, in competitions, wings of chaos grow in me, so i will find chaos on the track, and we will show what the firefighters and the decisive stage of conquering the tower are capable of, the team that will rise to the main crystal will become the winner of this level and it was very difficult to continue his struggle for a place in the final. entertaining show heroes on belarus 24 tv channel hello, we are probably the only ones in the republic of belarus who still produce the

good old tasty moscow sausage exactly according to the gost recipe . cis is even better. yes? it's just, what a rare story a woman fucks, right? this same says not forging. it's lightly hammered. but no, the second leg, she hid under and she, as it were, there is absolutely no rus with svetlana borovskaya on our tv channel. what is even possible?

why would you? well, after she left, we did not contact her. flew in remember, 24 karpenko avenue, apartment 60, she is there watching the series crossroads this weekend on belarus 24 tv channel. in one of the laboratories of the institute of experimental veterinary medicine in belarus, scientists are studying bee diseases, the most important problem in this direction

today. it's literally an attack on honey bees all over the world, starting from the seventies of the last century, the parasitic varoro mite, according to scientists, this pest poses a real threat to the existence of beekeeping, as such it complicates the episodic situation with more than 7,000 viruses, which are currently known, more than 24 viruses are isolated in common and honey. that is, uh, the call itself is a parasite. uh, besides the fact that he himself, uh , directly causes a lot of damage. an entire branch of beekeeping, however, it delivers families directly, feeding on the fat body and direct contact, are obtained with viruses, that is, the bees are additionally infected with viruses in this way. for example, according to the latest data, such a disease as the wing deformation virus is

actually widespread in russia and belarus is also recorded in the case of this disease. to be more visual , the mite represents such a flaxseed species. here you can see a large amount collected in this jar. uh mite, to slightly compare the size of the bee mite. i would tell you that a tick that parasitizes on the body is actually for a person. well, a backpack measuring somewhere around 20-24 kg on the shoulders. in pupae and adult bees, a severe disease of the gate wasps , most drugs for this disease are toxic. in some cases, even bees are brought to death, our scientist managed to create an environmentally friendly , safe and mild preparations. to date, the scientific project has been completed, within the framework of which, together with the institute of fruit growing. ah

an industry laboratory of beekeeping has developed a veterinary drug crowd here is a sample of a veterinary drug. the effectiveness of the use of drugs, depending on the time of year, was more than 95%. now scientists are working on the creation of new equally effective drugs. what other viruses do dmitry study, or maybe there are some directly relevant work being done in four main areas. these are cattle viruses, swine viruses, small cattle and carnivorous viruses. if to list all of these, for example rabies virus animal viruses and sheep virus infectious rhinotherapy. this viral diarrhea reproductive porcine respiratory syndrome virus is a classic. why pigs and many others are only about 20 viruses that we work with. well, somehow it's all treated. if anything, if there is

some kind of bad story going on somewhere in agriculture. as a rule, we develop complex preparations. we have a separate line. this is the development of environmentally friendly drugs, as alternatives to antibiotics, the development of antiviral drugs. these are drugs based on immunoglobulins. we need particles of lactoferrin bioelements, that is, i cannot but ask such a plan of the drug, but recently we often hear that it is on one farm on another. uh, if you go livestock, the reasons may be different, but you can contact you, uh, somehow this problem can, well, at least stop this process with one of the services provided by the institute for livestock farms. this is a scientific and practical help. livestock farms often turn to us on various problematic issues. in response to these appeals, the institute sends specialists who oversee various areas. this is an infectious profile or and parasitic disease

obstetric gynecological disease metabolic disease of the extremities and e, to establish the causes of non-productive being. our specialists assess the exotic situation, look at the state of feeding of the animals on the farm and, in accordance with this, are carried out. yard biological material laboratory test to confirm the diagnosis and have already received. uh, some results, then we give appropriate recommendations, adjust the vaccination schemes for therapeutic and prophylactic treatments. that is, act here in this problem according to the situation , i understand correctly, of course, each time the situation is different, so a creative approach is needed here. and there are some. well, let's say the issues that are relevant are their permanent accounts. well decide annually. so i constantly have questions, and you know, in general, a viral infection. she uh, let's say so strives to constantly circulate in the animal population, and for this

nature has developed various mechanisms. that is, the virus can become chronic and then become more active periodically outbreaks of the disease. that's the way. we must adapt to these mechanisms, study them and develop, accordingly, preventive and treatment measures that will ensure the well-being of the country, and seasonal ones. animals have some kind of history, here are the people there in the fall, standard sars influenza. yah covid. now, yes, in the spring the same story, but with animals it is the same. yes? of course, all diseases are seasonal. it is usually rather the beginning of spring. uh, the end of autumn also activates various viral infections , bacterial infections are layered, a and animals naturally fall ill and already appear, uh, clinical symptoms, on which we must already respond. thank you very much. very interesting. we don't say goodbye, i remind you. you

alkama. thread today learning how to work modern aibolites and see below. in a good mood with a smile on your face. the main rule for creating cells. and viruses sounds and animals. why are scientists increasingly using cellular material for experiments? and new research in the field of veterinary medicine will tell about them very soon. the hottest event in the world of sports for the number one game in the small gulf country has been built from the ground up by hard training and exciting competition. that is, there will be an uncompromising struggle, an interesting game and my career for my story. it will be great. an event, if we can achieve this result , such, the most turning point, probably

begins somewhere around the thirty-fifth kilometer, when the body is already one-sided, you already switch to such moral and volitional qualities of victory and defeat, i was glad for myself that everything -i was able to climb, strength appeared inside myself to start all over again, try, a chic base of 16.4. yes, his manner of execution and stability they allow us to count on the highest place. watch in sports projects on the tv channel belarus 24. ancestors are real male crafts and myths and legends are nearby popular culture in all its glory watch every week the

culture fashion project on belarus 24 tv channel. why the same events and circumstances are treated differently, who creates new ethics and new informational trends, and who benefits from it, no matter how strange it may sound to someone, but there is documentary evidence of this and these plans for many years were hatched secretly and were not voiced aloud. and these are proven facts. or is it different ksenia lebedeva will tell you in detail about the phenomenon of double standards. and how they work in the project. this is different, do not miss it on belarus 24 tv channel. studying

animal viruses is now almost impossible without creating cells, this method does not violate ethical standards and gives accurate results. experimental veterinarian natalya ivanovna good afternoon. good afternoon natalya ivanovna kostyuk head of the cell culture department and nutrients of the institute of experimental veterinary medicine of the national academy of sciences of belarus candidate of veterinary sciences associate professor natalya ivanovna well, for starters. tell us how you grow cells in general, what biomaterial you use, and how it all looks like. that is, this is a test tube laboratory. as a cell culture, these are cells of multicellular organisms that live and multiply in artificial conditions . cell culture can be obtained from almost any organ or tissue and grown separately in a test tube.

paints. as the principle itself occurs, most often it happens in the conditions of the meat processing plant, we get the organ that we need. there's a piece of liver skin and so on. well, for this there is no need to kill animals. all this is done under very aseptic sterile conditions, it is brought to the laboratory, the tissue is crushed and there is a special solution, under the action of which the cells leave the organs and pass into the solution. this is a very long monotonous process, very complex, but , in principle, master it. any person can. if you like it, such work is further for these cells. it is necessary to create conditions. the main thing is the substrate to which the cells must attach, where they will grow and multiply, a nutrient medium and heat are required in order to grow cell cultures, i have a special medium, for example, medium 199. it contains more than 60 components. there are all vitamins, 17 amino acids, proteins, minerals. this is a rather very

complex medium in its composition, which in this nutrient medium and in warmth is always the temperature is needed 37-37 °. well, the same as the animals we have with you. we work at the institute. mostly with pererevaniya cell lines. they are also called immortals, that is, these cells were once received from organs long ago. they are late for special storage conditions when they extract from these storage conditions. they feel great and move on. we have cells of 78 years received in their bank. eighties ninety-six and we are successfully extracting them from cryostorage and working with these cells. here cryostorage. you said that one of the conditions is a low temperature. i'm right, this is a bank in general e cells, what is it and what are the conditions? here, in addition to the low temperature, we have quite a lot of vessels with dura, in which

liquid nitrogen is poured, the temperature of which is -196 ° and the cells are stored there in such a frozen state, and they are stored for a very long time they are also called immortal, that is, you can extract them at any time from the bank you create special conditions, and they feel great and live come alive. yes, we recently raised the line of 1986, and it still feels great with us and the present moment is growing. you said to grow a cell. uh, maybe everyone. the main thing is to like working, but i know that there must be a good mood. or is it a myth, really, she feels that when we go to work with cells, we leave all the sorrows behind the doors of our boxes. and when you sit down to work laminate, you really forget about a bad mood, well-being, and so on, in general, this is not very good, of course, it’s like quite a myth there were cases when here we have