who is being checked? similar incidents were recorded by the belarusian authorities, the border service and at the end of last year twice in november and early december. the ministry of internal affairs of poland announced the indefinite closure of the bobrovniki border crossing on the border with belarus from our side. this berestovitsa checkpoint confirmed the information to the state border committee, saying that tomorrow, from 12:00 , the polish checkpoint bobrovniki officially suspends the clearance of vehicles and persons following the state border, let me remind you in the fall of 2021. in one way in order, another checkpoint of the smithy belostotskaya from the belarusian side of bruzgi was closed for freight transport to poland . expenses for the destruction of history for operations to erase the sacred memory do not

spare money estonian authorities the ministry of finance of the country is ready to allocate one million 420,000 euros for the dismantling of soviet monuments a request to cover the costs of removing historical objects from public space. the estonian ministry of defense has addressed the request will be satisfied, of course, at the expense of estonian taxpayers. at 19:00 more relevant information see you. if you have n’t come up with your dream trip yet, then we always have a couple of great options. this is the highest mountainous settlement in belarus , which, moreover, became famous, we recall the lessons of history, as the first capital of the grand duchy of lithuania. our country in 1519, thanks to the zealot of orthodoxy konstantin ostrovsky, the temple

acquired the shape of a ship. this photo was taken in 1914. this is how the temple flew out as a cross and was also preserved; interesting tourist routes of the complex are laid out; a mini zoo is located. therefore, i propose to communicate with its residents, who are not afraid of winter, and share their first impressions. on belarus 24

siberian ulcer scabies rabies hepatitis diabetes mellitus all these diseases can still affect animals and our domestic pets and, speaking with the language of agricultural animal specialists, the most important enemy remains a viral infection, which our veterinarians successfully fight only as in everything. first , the work is carried out by scientists, the virus is isolated, grown, studied, and then vaccines are created. however, let's not get ahead of ourselves and start to understand the topic in order. my name is ekaterina beretskaya. hello. today in the new company. we will study the recipes of modern aibolites. don't miss the next half an hour. vaccine dna new

generation of vaccinations for animals so that the bees do not get sick. what drugs scientists create for insects and solve the issue on the spot, how scientists save animals on farms in the program very soon. the institute of experimental veterinary medicine of the academy of sciences of belarus was established back in the twenties of the last century, and in the past, present and future, of course, my colleagues asked all those involved right at the solemn event dedicated to the centennial anniversary of the institute. for a century, the institute of experimental veterinary medicine in belarus has been developing new methods for diagnosing and treating animal diseases. the

vasilevsky institute of experimental veterinary medicine is a fairly significant scientific institution. for a long period of time, the enterprise has been quite effectively developing the production of veterinary vaccines, serum vaccines in some other areas, and they are constantly improving and interacting with our universities. first of all , local veterinary preparations are being developed and practically ensure the biological safety of our country. many of the developments are successfully sold abroad, there is a special demand for vaccines against various diseases. we produce on an industrial scale, for example, the countries of central asia buy a vaccine against sheep pox from belarus, and as soon as a new virus that infects animals appears. our scientists are trying to find a new way to protect a vaccine or antidote. appeared, as it were, uh, new topical infections. it's, uh, african swine fever, it's

supra-bovine dermatitis, uh, other infections. in particular, there is problems. now pathogenic influenza in the world of birds. this is a disease that, in particular, is transmitted to humans, and there is a danger of infecting people, so we have all these problems at the institute. naturally studied we are working on these problems. plus. uh, we are doing some fundamental research for the future. here in particular. right there in our department. uh, new promising drugs that will be aimed at treating exactly the place that is sick, that is, pointwise. that is, the antibiotic will act locally without harming everything the body of an animal, and this is a real breakthrough in veterinary medicine. few people know, but the largest

collection of deadly viruses today is located just in the laboratories of the institute of experimental veterinary medicine of our academy of sciences, we will continue the topic with the first guest of drug addiction dmitry sergeevich hello dmitry sergeevich borisovets, head of the department of viral infections of the institute of experimental veterinary medicine of the national academy of sciences of belarus candidate of veterinary sciences assistant professor. i understand correctly that this is the same collection of deadly viruses in order to make it convenient for you to find these viruses in our animals. yes, absolutely everything to work. yes, of course at work. now, i know, you are engaged in the creation of new generation boxes. please tell us about combined vector and even dna vaccines, what is it for, what is the department of viral infections of the institute of experimental veterinary medicine. for over 50 years. e is working on the

development of vaccines for veterinary medicine during this time, more than 80 different biologics for animals have been created and the technology that is used to create these prices. this is classic technology. that is, when we isolate a viral pathogen, we accumulate it on the cell culture, and then inactivate it, if you are a killed vaccine, it further introduces auxiliary components to form the final product, but naturally science does not stand still and new directions are developing, including biotechnology . genetic engineering, we are also moving in the same direction, and in this regard, we are also developing the direction of developing new generation vaccines, this is a recombinant vaccine vector vaccines dna rna vaccines in this regard, we work closely with the institute of biophysics and cell engineering of the national academy of sciences of belarus and, uh, two main directions. this is the development of vector vaccines - these are vaccines that are developed against viruses that

are difficult to accumulate and difficult to culture. in particular. this is a respiratory sensation virus and the second direction is a marker vaccine, when a specific marker. we integrate the virus into the genome and such vaccines make it possible to distinguish the vaccinated recovered dna yes and no, this is not a dna vaccine. this is a marker vaccine, they are being developed, mainly for diseases such as infectious rhinotrant , classical plague, swine, travel sickness virus. as for dna vaccines, i would like to note that not all technologies that work in medicine are always acceptable for wind farming. that is, for example, as the covid-19 pandemic showed, the developed dna vaccine should be stored under conditions e, at -80 °. that is, specialized equipment is required, that is, to supply our livestock enterprises. quite problematic, therefore, given these features of the storage of this vaccine. there are a lot of difficulties here, okay. we haven't yet explained what vaccine recommendations

are - this is when we cut out a section of the nucleic acid of the virus, which is responsible for the production of specific proteins for it, and this section. we are embedding in some kind of viral vector. that is, as a rule, it is a safe virus that does not cause disease in animals, but it is a carrier. nucleic acid inserts into the cell and thus provide a whole cascade of immunological reactions that contribute to the development. relevant immune response know that wild boar pigs found a new disease hepatitis. e. in our country, it was recorded and is it worth it for people to be afraid, we detected cases of hepatitis during the period of the afghan war, cases of illness of our military personnel were noted and hepatitis was diagnosed. as a result of which he became

the discoverer of this virus. and in principle it was believed that this disease was viral hepatitis. e. it is more typical for countries with a hot climate when drinking, for example, poor-quality water. later in 2003, it was found that this disease can be transmitted from animal to person, namely, when using thermally poorly processed meat and liver from wild boars from domestic pigs. and this deer and was subsequently established. what exactly is the use of termi. and badly crafted meat is one of the causes of this disease can be prevented in animals this story. i know that you are working on the development of preventive measures for 2016 , and we are participating in an international project within the framework of the union state in the implementation of this project, we have developed diagnostic test systems for diagnostics for the purpose of monitoring - this is in the enzyme immunoassay of a polymethine of various chain reactions and one of the tasks. there was also development. ah, systems. uh, preventive

measures - this also applies to rural medicine economy, that is, for man. this is more about personal hygiene. this is eating well thermally processed meat and liver. and also, for example, if a person travels abroad, it is recommended to use bottled water, as far as agriculture is concerned , but this is more about observing safety rules on farms, and timely cleaning and disposal of manure, as well as disinfection and quarantine of animals upon receipt of them to the farm. how about a virus. uh, the animal you discover. well, as i understand it, here are these test systems. yes, some, well, just, again, you won’t take the animal to the veterinarian and you’ll find out, and he won’t say there, something hurts me. look, yes, of course, the peculiarity of this disease is that pigs, as a rule, are ill with asymptomatic and it is very difficult to detect clinical e, the signs of this

disease are very difficult, therefore laboratory research methods help here. systems, which will allow laboratory conditions to determine e, diseased animals, as well as after the infection has been recovered. that's just in the laboratory of your institute. my colleagues have gone. let's see what they saw there. their technologies are our comfort and safety today for any specialist who works, regardless of the sector in which he must have the skills of energy-efficient technologies that save energy every time he comes to work. this is my chess game, because i need to plan and organize the work. so all this equipment worked. they tell complex things in simple terms, and here is the imitation of the sun's rays and the light

that imitates the sun heats the panel, uh, converting the energy of the sun into the energy of heating water for the house is at -20 mark. this is the lowest point of our career. if we compare it with the level of the baltic sea, then we will say 20 m under water and share the intricacies of his work, which he simply loves to drive a car. yes, it looks like a toy, but it carries 90 tons of rock, we are making a start in future to innovate. this is the care of the state about the nation of its education. watch the one day project on belarus 24 tv channel. why do paintings read in the east : painting, calligraphy, ceramics and porcelain , an amazing work that keeps its

history and is full of mysterious meaning? we will visit the exhibition, belarus china cooperation and friendship project fashion for culture, watch this weekend only on our channel. work brought study and love to belarus. my name is alexei verkhoven. first of all, i am a nasiphonic conductor. and i came from russia i want to do an internship already as belarus , and after that i will start working as a doctor. each hero has his own unique story and his own view of belarus, but in fact, the theater is the bolshoi theater of belarus we see from russia in the same way as you see marinka in russia for us it is, well, the bolshoi bolshoi

theater with a history with a reputation, belarusian , people. it takes a very long time even the belarusian anthem begins. we are peaceful people in belarus. very nervous people. very loyal people very calm people. yes, wishfull e hard-working look at the program look at belarus on our tv channel. in one of the laboratories of the institute of experimental veterinary medicine in belarus , scientists are studying bee diseases, the most important problem in this direction today. this is literally an attack on honey bees all over the world, since the seventies of the last century, the parasitic varua mite, according to scientists, this visitor poses a real threat to the existence of beekeeping, as such, this directly complicates the

episodic situation by genus. of the more than 7,000 viruses that are currently day known more than 24 viruses isolated common and medonomous. that is, uh, the call itself is a parasite. uh, besides the fact that he himself, uh, directly causes a lot of damage. at the same time, it delivers to the whole branch of beekeeping the families directly with the chinese prayer, direct contact with the body, it turns out with viruses, that is, the bees are thus additionally depicted. accordingly, such a disease as the wing deformation virus is actually widespread in russia, and cases are also recorded in belarus. to be more a clear mite represents such a flaxseed kind of flaxseed. here you see a large

amount collected in a jar. e tick, to slightly compare the size of the tick and the bee. i would tell you that uh, a tick that parasitizes the body in chile. this is actually for a person, but uh, a backpack the size of somewhere around 20-24 kg on the shoulders. causes bugs, pupae and adult bees a severe disease of the wasp gate, most of the drugs for this disease are toxic. in some cases, they even bring bees to death, our scientist managed to create environmentally friendly safe and mild preparations. to date, the scientific project has been completed, within the framework of which, together with the institute of fruit growing. uh, the branch laboratory of beekeeping has developed a veterinary drug tolpan, here is a sample of a veterinary drug. depending on the season, it was more than 95%. now scientists are working on the creation of new equally effective means. what other

viruses do dmitry study, maybe there are some really relevant ones? work is being done in four main areas. these are viruses bovine porcine viruses, small ruminants and carnivorous viruses, if you list it. for example , animal rabies virus and sheep virus infectious rhinotherapy. this is viral diarrhea. uh, reproductive respiratory syndrome is stronger than the classic virus. why pigs and many others are only about 20 viruses that we work with. well, somehow it's all treated. if anything, if there is some kind of bad story going on somewhere in agriculture. we usually develop complex drugs. we have a separate line. this is the development of environmentally friendly drugs, as alternatives to antibiotics , the development of antiviral drugs. these

are based drugs. uh, immunoglobulins, but nanoparticles of lactoferin bioelements, that is , i can’t help asking such a drug plan, but recently we often hear that it’s on one farm on another. uh, you go cattle, the reasons may be different, but you can contact you, uh, somehow you can this problem, well, at least stop this process of one of the services that provides institute for animal husbandry. this is scientific and practical help. we are often approached by livestock farms on various problematic issues. in response to these requests, the institute sends specialists who oversee various areas. this is an infectious profile or parasitic disease. obstetric gynecological diseases, metabolic disorders, diseases of the limbs, and e, in order to establish the causes of a non -productive event, our specialists evaluate the episodic situation, look at the state of feeding the animals on

farm and in accordance with this, a selection of biological material is carried out, a laboratory test is carried out to confirm the diagnosis and has already received. uh, some results next. we give appropriate recommendations and adjust the vaccination schemes for therapeutic and prophylactic treatments. act here in this problem on a situation correctly i understand. yes, of course, each time the situation is different, so here you need a creative approach. and there are some. well, let's say the questions that are relevant constantly have them. well decide annually. so i there are always questions. and you know, in general, a viral infection. she, let's say, strives to constantly circulate in the animal population, and for this, nature has developed various mechanisms. that is, the virus can become chronic and then become more active periodically outbreaks of the disease. this is how we must adapt to these mechanisms, study them and develop, respectively , preventive and treatment measures that will allow us to

provide. the well-being of the country, and the animals have some kind of seasonal history, here are the people there in the fall, sars flu is standard. yes , covid. now, yes, in the spring the same story, but with animals it is the same. yes? of course , all diseases are seasonal. it is usually rather the beginning of spring. uh, the end of autumn , various viral infections are also activated, bacterial infections are layered, a and animals naturally fall ill and already appear, uh, clinical symptoms, on which we must already respond. thank you very much. very interesting. we don't say goodbye, i remind you look at lukomaniya today, study the methods of work of modern aibolites and see yes next in a good mood with a smile on your face. the main rule for creating cells and animals is a whole. why are scientists increasingly

using cellular material for experiments? and new research in the field of veterinary medicine will tell about them very soon. do you have cows? we are the edge, blow 25-25 and we are berries again, not at all again, but also nothing. here is the heavenly beauty of the red rabbit. yes, what a beauty, but the symbol is the symbol of the new year. yes we are marshmallows we go in pairs, and the herring, as it was to everyone, dear to the heart, is so. how many spoons in the team i already have belarusians, see good differences, belarus with svetlana borovskaya on our tv channel. rules of order and priorities

against a common enemy, how important it is to make a decision based on knowledge of not on the case of distortion. lies and manipulation are those effective methods of influencing people that have been tested for centuries. how to find a reasonable way to balance the conflicting interests of the enemy, it is still better to know in person. and although the world are we preparing for war, or is it something else, ksenia lebedeva's author's view of the policy of double standards in the project is something else, watch belarus 24 tv channel. topics that are difficult not to touch on and questions that cannot be asked. anna has recently become anxious people. more. do not find, downright, a mass epidemic over any person hovers what is called unformulated anxiety.

in general, emotionally human, therefore, at all times it was present in people. well, in the most anxious responsible times. no matter how strangely people are getting kinder to each other comments and recommendations from experts who have studied the essence of the situation, a wonderful technique that i always recommend to clients. it is to keep a diary of feelings and emotions. that is, in a good way, anger is like mothers. that is, if i feel angry, then this is a signal for me, either my needs are frustrated, or someone, uh, has climbed on my border. well, at least you consider the fact verified, because bloggers are one and the other, watch the project concept on belarus 24 tv channel. studying animal viruses now

practically impossible without creating cells, such a method does not violate ethical norms and gives accurate results. i was intrigued, then i won’t do it anymore. there in my studio, the head of the department of cultures, cells and nutrients of the institute of experimental veterinary medicine natalya ivanovna good afternoon. good afternoon natalya ivanovna kostyuk head of the department of cell cultures and nutrients of the institute of experimental veterinary medicine of the national academy of sciences of belarus candidate of veterinary sciences associate professor natalya ivanovna nu to start. tell us how you grow cells in general. what biomaterial do you use and how does it all look like, that is, these are test tube laboratories. as a cell culture, these are cells of multicellular organisms that live and reproduce under artificial conditions, cell culture can be obtained from almost any organ or tissue and grown separately in a mattress test tube. as the principle itself occurs, most often it happens in the conditions of the

meat processing plant, we get the organ that we need. there's a piece of liver skin and so further. well, for this there is no need to kill animals. all this is done under very asymptomatic, sterile conditions , tissues are brought to the laboratory, crushed and a special solution is used, under the action of which the cells leave the organs and pass into the solution. this is a very long monotonous process, very complex, but, in principle, master it. any person can. if you like it, such work is further for these cells. it is necessary to create conditions. the main thing is the substrate to which the cells must attach where they will grow. multiply, be sure to have a nutrient medium and heat in order to grow cell cultures, i have a special medium, for example, medium 199. it is contained in more than 60 components. there are all vitamins, 17 amino acids, proteins, minerals. this is a rather very complex medium in its composition, which in this nutrient medium and in

warmth always needs a third temperature of -37 °. well, the same as the animals we have with you . we work at the institute. mostly with interrupted cell lines. they are also called immortals, that is, these cells once upon a time received from the authorities. they are late for special storage conditions when they extract from these storage conditions. they feel great and live on. we have in the park cells received in '78. eighties ninety-six and we are successfully extracting them from cryostorage and working with these cells. that's cryopreservation. you said that one of the conditions is a low temperature. i'm right, so here's the bank in general e cells, what is it and what are the conditions? here, in addition to the low temperature at we have quite a lot of banks a vessel and a dura, in which liquid nitrogen is poured, the temperature of which is -196 ° and cells are stored there in such a

frozen state, and they are stored for a very long time they are also called immortal, that is, at any moment you take them out of the bank, you create it special conditions, and they feel great and live alive. yes, recently we raised the line of 86, and it still feels great with us and grows in the present moment. you said to grow a cell. uh, maybe everyone the main thing is to work i liked it, but i know that there must be a good mood. or is it a myth, really, she feels that when we work with cells, we leave all the sorrows behind the doors of our boxes. and when you sit down , laminars work, you really forget about a bad mood, well-being, and so on, in general, this is not very, of course, such, as if it were a myth, there were cases when we have, well, a lot of young mothers, that's when the children got sick cell ceased to give a great

harvest, well it was for some period of time. we noticed it. here, each employee has his own favorite cell for one reason or another, someone likes it, outwardly someone that it gives a big harvest for virology. now let's move on to the results of your labors. yes, use now, uh, the issue of bioethics animals is becoming more and more relevant. that is why you work closely, if virologists and now this whole thing also happens at the cellular level, not only. white ethics here, of course, has contributed. back in the fifties, when it began to develop in russology. at the same time, cell culture began to develop, and when the channel realized that it was possible to work on a cell, to see how the virus interacted with the cell. cell culture began to develop and the first vaccine against dust and militia was obtained in 54, thanks to. here is the vaccine.