during their fights, the coldest heroes will share unbelievable prague, even though everything worked out for me here, and i don’t regret a bit that i stayed in this wonderful place. i, for example, uh, polished i'm proud, i stop by minsk, i say, yes, yes, i

'm a damned look at the poleshuka project on belarus 204 tv channel. non-random. name god's wok, in spite of the lake otrymalo dyakuyu with its obrysam ikea they drive a wolf into lake maya, the shape of the correct circle, which does not change for a long time, i eat on the far, that the wok sorches behind the right of people from heaven and shmatevshi of such choral chandeliers in belarus people thought about this question from the most ancient times, it was raised in egyptian

indian and chinese treatises , which managed to be found and deciphered in our days. it ’s just that experiments in this area sometimes ended tragically under such circumstances, for example, the chinese emperor qin shihunde died in the modern world before fortunately, things do not reach such extremes, although the search for it continues, to this day in the next half hour we will join them in order to understand how close science is today to the discovery of the elixir of youth, and it is about him that it is not excluded that it is already very close in the court of ekaterina meretskaya hello and do not miss the program. alchemy and even magic, where ancient thinkers tried to find the elixir of youth, according to what laws does

the human body age? and how these processes can be suspended, we will find out very soon. to reveal the secret of youth and health, the chinese emperor uzi in the second century bc turned to magicians, and the first to alchemists. in the third century, already our eras devoted their works precisely to the search for a cure for immortality, let's trace all the historical stages , right now in search of the so-called source of eternal youth, the spring, about which the legends went on an expedition, the spanish conquistador juan ponce de leon the spring, of course, have not found. but he discovered florida in 1550, the venetian

aristocrat luigi carnara published a book the art of longevity, which described the basic principles of life, helping to stay healthy for them. the author attributed sleep, moderate nutrition and lack of stress to the first scientific ones. not in this area began at the end of the 19th century in 1882, the german professor august feisman published the first theory of aging, and in 1903 the russian scientist ilya mechnikov introduced the term gerontology, the doctrine of old age. through experiments, he found out that nutrition affects life expectancy, after 25 years, also a russian scientist alexander bogdanov creates the world's first institute for blood transfusion. since he believes that it is in this way that the body can be rejuvenated, however, during the next transfusion, scientists die at that time nothing was known about the compatibility of blood types a few years later, a swiss

doctor. paul nihon develops a method for injecting stem cells. among his patients would be churchill and charles de gaulle during the second world war, almost all research in this area is suspended and resumed. only after it ends today there is many theories of aging, which can be conditionally divided into three main groups, immunological cellular and genetic. new recipes for slowing down the aging process appear almost every year, but after lengthy research studies , far from all prove their effectiveness. literally at the beginning of 2023, employees

at the university of california at san diego developed a way to potentially slow down the cellular aging process using a fluctuating genetic clock, which is the essence of the previous ones. studies by this group of scientists showed that cells age as a result of two processes , a decrease in the stability of dna and a decrease in the energy produced by mitochondria as energy centers, cell scientists came to the conclusion that aging will come later. if the cells switch between these two processes, the method was tested on yeast cells and obtained excellent results. what belarusian scientists think about the latest research of a group of scientists from the university of california san diego and what they are working on in this area we ourselves will ask our guests in the studio of the program. today, the head of the laboratory

of neurophysiology of the institute of physiology of the academy of sciences of belarus svetlana georgievna hello hello so tell me like this in plain language. what is the method of such cell switching, how does it work? there is genetic information, which, let's say , of two varieties will be easier to compare. uh, our processes of forming memory and information at the cellular level with a computer. but imagine that the genetic information that is stored in our dna in the genome. she passed down to us from generation to mouth from our parents from our ancestors. this is the so-called hard drive. this is such a biological device. that's all that represents in the computer. well, where we will load. but the fact that we download the software is epigenetic information. this is our software software can be completely different depending on the environmental factors that

a person encounters in life, this is both internal and external , how we adapt to them. and that's all the most successful they are stored on the hard drive, that is, in our gene already, and er, when scientists began to analyze. uh, what causes aging, aging, the genome wears out, but, because copying errors constantly occur and, uh, as a well-known fact that has been known since the fifties that in every cell, and every day, there are, well, a violation of the structure here are double-strand breaks, dna from 10 to 50. these are the breaks that need to be repaired all the time in order to restore these two. on breaks, for example, or a general disruption in dna , require information to be requested from the epigenome. and how often we request this information, so the cell gradually changes its essence. that is, it loses its identity. that was a cell. hmm, which, uh,

had a certain function. well , for example, it was a muscle cell. she worked beautifully. and suddenly it began to lose these functions and began to turn into a connective one. what is it associated with the loss of muscle tissue during aging and the replacement of connective tissue, that is on the one side. these are dna repair processes on the other hand. in fact, this is the aging process. that is, this positive moment, which , well, let's say, the cell loses its identity and, accordingly , does not perform its function well, let's not put windows on it let's put linux, maybe it will work with it, but that will be a completely different story, though, a completely different interface, of course, and then the somatic cells simply began to reprogram

the old somatic cells into others into young ones, and they began to live normally and began to work normally , so you can take these cells from the old organism, move them to the young organism and it will live quite a long time, but another point, if we take this young cell of the organism and move it to the old ones, but it still dies its time, the question arose of how the interaction between these two clocks, the gene and the epigyn, occurs, and found that there is no direct path? yes? here is a straight line, and sometimes a short line, this is a lightning, yes, that is, a zigzag is always closer, that is, this is the opportunity to maneuver. this information provides, first of all , new challenges for scientists. this means that it is necessary to reveal not only the secrets of our genome and epigenome separately, we interact with them. and this is already, well, a completely new interesting field for the study of all scientists, in which, of

course, those people who have a desire will win. e, to scientific search and with the vivacity of your thoughts, so to speak, all this could already be said that there is nothing directly sensational new, but there are prospects, and in this study there is every time. uh, each new step, and it is actually quite significant, and although for scientists, because. they work with it all the time these steps are natural and so we do very often. i think that belarusian geneticists do not always, but appreciate it. that their research is at the highest world level, because it seems to them that it was just a small step, but, well, they would write about them here in in the same vein, and you can imagine how much it would turn out that in belarus there, well, even cooler than anyone there, harvard californian , and so on, that is, all these

studies. in fact, all this is in the world treasury of knowledge and all this is for the benefit of man. but then i propose, so to speak , to promote our scientists, my colleagues went to the institute of genetics to understand this topic in more detail. let's go on an expedition to the cups of our crown . blow. you do not say hello, lie and rust pears history for a whole breath on the walls subdued to walk. i have made kuchera people come to this day, after i get out of two factories. what are the first sent to the young great traditions of the son, i do not have a woman , the khan is no longer coming. new aunt.

you will be sorry for you alone, we will raise the project to fifth on the tv channel, belarus 204 at once

. according to scientists, our beauty and youth are 25 percent dependent on genetics and some even incurable diseases, mainly the manifestation of which is early aging arise precisely because of the breakdown of the elements. dna is the well-known progeria , uh, which is divided into progeria of childhood and is caused by mutations of eugene that encode lamin, that is, there is a violation of cell division and such children die before the age of 27 and there is progeria of adults. e, is caused by another gene, e, which is responsible for the normal functioning and normal

structure of our dna and causes changes in the medial tissues leading to development. various atherosclerosis and such a disease appears at the age of 30-40, too, people already look , in general, rather elderly, and these diseases, unfortunately, are not treated, both in childhood and in adults and naturally symptomatic treatment. in general, purely genetically, youth is a healthy state of the body. and it depends on this how early the external signs of aging will appear, for example, wrinkles in the study of youth by geneticists around the world , several main directions can be distinguished. the first is the effect of oxidative stress on the body. if we talk like this manifests itself, then it manifests itself, first of all, it will be increased fatigue, which, in general, is characteristic. probably for all of us this is an early appearance. ah, holy hair. uh, early appearance - this means the first seeds are already appearing in the summer of 17-18. and hair. this is the peculiarity of these gray hairs, what if we normalize our work of the antioxidant

system, which copes with ex-dative stress. uh, then uh, these hairs disappear, that is, naturally, hair color is acquired here, of course. these are the enzymes etioxidant system. they are encoded. naturally, certain genes and mutations and changes in these genes lead to an imbalance and a violation of the increased content in our body of these active e-e, bio-oxygen molecules, at the institute of genetics, we in belarus, such studies also conducted a connection of extremely negative influence. and by the way, it has been proven on the body that, in addition to internal damage , our appearance also suffers. however, our scientists also have this problem. they didn't leave without attention. a new direction that our institute is engaged in this is cosmetology. uh, this is the condition of our skin, the condition of our hair, uh, and uh, there is a disease, that is, again, alopecia, that is, hair loss is quite a large group of diseases, and

one of these diseases is androgenetic alopecia, which is caused by er, it has a genetic nature, e. eh, these are the defects. to date, it has been established that every second woman is a carrier of these genes. yes, the disease is more common in men. there you can talk about eight out of ten men, genetically stated hair loss problem has become more common in a younger population and can manifest itself as early as the age of 20 years. the rejuvenation of this disease leads to the fact that the correct diagnosis, existing methods of prevention and treatment of this disease are not always immediately put. they allow you to set to slow hair loss. that is, if the diagnosis is made correctly, and here, of course, genetics comes to the rescue. that is, if people there in the family have a known case of alopecia, then you can apply to do a physical test, er, and the doctors

select the correct increase, that is , the correct prophylaxis, er, and the person remains with his hair. and one more direction on which our geneticists are working. this photoaging is basically damage to the skin, uh, that's caused by either the sun's rays or ultraviolet rays. uh, and as much as we are skeptical about this, it is believed that uh in people prone to photoaging. e their physiological age differs from the external one by 20 years, that is, a person looks 20 years older than he is. yes, in fact, the first sign of this photoaging, which is associated with genetic defects, is hyperpigmentation, that is, an increased content of moles there, do not listen, too , this can be generally determined, uh, in the presence of certain defects of the gene and after a genetic diagnosis a set of care cosmetics is installed, which

will protect the skin. you are watching the science project nearby and don't miss any further. why do our cells stop actively dividing as we age? let's take a look at how our brains age. and together we will study the new rule of medical examination. oblivion is the very first step towards distortion . the average belarus will always figure out provocative details and answers to the challenges of the time in society now. there is a request very much justice. no need to make excuses. do you know why? because when a person has learned the four basic rules of management, yes, then in general it doesn’t

matter what he manages. he just has to have his head on his shoulders, they serve in three structures. it's in the army in the church. and all in the theater, so let's just say not very far, but there is a concept, operational artificiality, theatrical art. how do you stand not to become an actor in someone else's game? the main thing was not to wait for the command, you should not be afraid to take responsibility. i'll probably re -emphasize two things that are taken advantage of. i liked them, the decency of the name of the project. nothing personal just the truth, which is always interesting. her conjectures, look at the tv channel belarus 24. from me, some problems have not yet begun. that's when everyone will know there will be a disaster. mukhin is needed . there are no vacancies yet. so i can

offer you a job around the clock loading for a few days, working, highly paid. i'll explain everything to my husband, if it becomes known that you feel bankruptcy.

we return to the studio. i remind us at a party. today the head of the laboratory of neurophysiology of the institute of physiology of the academy of sciences of belarus svetlana pashkevich, svetlana dahlia. let's take a look at how our body ages. well, let's just say it's clear that genetics is genetics, but still some processes, they are natural in the body, because that we change the cellular composition , our blood is constantly updated. uh, we are renewing the cells of our body. for all of our lives. we can change up to 11 bodies, that is , imagine yourself when you were born. here is your body and imagine yourself. now is this one and the same body fundamentally changes have taken place in the colossal and only cells that have remained with us. all this time. these are the cells of the nervous system and the heart, and everything else, uh, was re-created by our body and was created and that and food. uh, food from those environmental

influences, and therefore the main focus, of course, in the aging process is on the aging of the brain and the aging of the heart is one of the theories that the heart has a finite number of beats. for all time , and the slower it beats, the longer a person lives, and people who live a more measured life, who communicate with each other, who do not have a cognitive deficit, that is. they are perfectly aware of themselves in the environment, their place in this environment, who have procreation when they they see themselves in their children, first of all, and they see their future not in themselves in their personal immortality, but the future in their children , the future in the environment in which they will live, then this prolongs the life of these people and reliably. we can say that centenarians have just such an outlook on life. what about accumulation? and so on. yes, this

is inevitable and every time you can say that the genetic information can get worse, but in fact, it's not only the genome that really gets worse, but it's also epigene, and epigyn determines not only, but those signs that accidentally fall on us. well, and those that we ourselves program ourselves. that is why people who are engaged in healing practices, who not only lead a healthy lifestyle, but understand what is really useful for the body. and what could be? well , you know, with such a bright wrapper, uh, in order to sell you something, which, well, people just want to earn. yes, on your desire to be healthy, therefore, awareness of people's awareness of those real processes that happen to us and the acceptance of old age, after all, why do we think

that we should be immortal? well, we can be immortal in our children, and most likely, those people who have no descendants die, but those who have children, who have grandchildren, great-grandchildren, but this is already forever true, that is, you already see how far you are generations ahead. this is your information. yes, they are alive, but focus on their own aging. it is necessary only from the point of view to bring maximum benefit and not only, uh, to your the health of the body. well, society and theory. e aging that exist they primarily consider, for example. and how can we preserve the cognitive functions of the brain and e, what we are studying in the laboratory is the possibility of recovery, and in case of some emergency violations or damage with the help of endogenous resources. uh, it's probably already known stem cells.

the so-called process of neurogenesis, which takes place in certain limited areas of the brain, but allows to a greater extent, of course, to restore our functions of orientation in the space of storing information, and, uh, storing information. and therefore, if we move, if we get to know a new area, if we learn a new language, get to know new people, then this allows us to preserve the functions of neurogenesis. here in these areas. and the same is the area that is responsible for our internal organs. and therefore, if we do exercises in the fine motor cortex , it is directly related to the preservation of cognitive functions, but because this fine motor skills of the hand is our cerebral cortex, which when we sort and massage with our hands like this. and ah, do not forget that the brain, uh, works only when all its cells are fed, it does not feed idlers, and therefore, if some structures of the brain

do not work for some reason for a long time. well, for example, you just lie on the couch, look at tv, well, you didn’t get up and didn’t pass, but be sure to walk around, at least there should be some kind of change, motor activity and intellectual activity, and this will massage your brain quite well and prevent those neurons from dying , which once in school they learned to write beautifully. many dahlias. thank you very much, everything, as usual, is simply accessible and, most importantly , interesting and useful. and we continue. today, only one single elixir of youth is reliably known, in fact, it is a healthy lifestyle and no matter how skeptical someone might be about it, there are facts according to statistics that age slower those people who play sports get enough sleep eat right and regularly undergo medical examinations with this year, by the way, in our country there is a new medical examination approaches, what has changed and most importantly, why

did my colleagues find out in the section tested on themselves. so that they don’t get confused and the index signs come to the office in which medical examinations are carried out in clinics , they are even applied on the floor. welcome to dispensary. and this procedure begins with a questionnaire, the medical examination begins with the fact that the questionnaire is filled in the questionnaire there are questions on the answers to which conclusions can be drawn, if a person has a sharp development of the most common diseases, socially significant ones are diseases of the respiratory organs, circulatory system, oncology, and e , predisposition to diabetes mellitus, and the percentage fills in this document , the nursing staff working in these offices evaluates and, depending on this

assessment, is already further determined. what yes surveys. are they needed by the patient? after the patient has filled out the questionnaire, a set of mandatory procedures is carried out with him. this measurement of blood pressure is an eye pressure check of the condition of the oral cavity, and then the medical staff finds out. what is your body mass index is calculated by weight and height. another important thing is the waist size, since these indicators are directly related to the state of the endocrine system. yes, and correct, or rather healthy work of the whole organism. if any of the indicators is not normal. these are already the risks of a variety of diseases, depending on these risks, and he will pass before the examination , tests will be sent, if necessary, to a general practitioner for a cardiogram. if necessary, then to a narrow specialist, and analyzes are given even in the same day and a cardiogram can be done, and then the patient can make an appointment at a convenient time for him to see a doctor. there they will explain the results to him and then, depending on

what is revealed, he will need to be examined, or they will tell you how to behave . what lifestyle and when to come next time? the medical examination procedure itself takes no more than 15 minutes and you have specific recommendations and directions in your hands. based on the results of the questionnaire, uh, you will need to undergo a cardiogram, pass cholesterol and visit a general practitioner medical examination from the age of 18. everyone will need all the citizens of our country. according to the latest decree, which was issued on august 9 , the twenty-second year, number 83, the conditionally adult population is divided into two groups. the first group is from 18 to 39 years old, the second is from 40 and older, the first group is patients. they undergo medical examination once every three years, the second time a year, but if a person has a disease, then it does not matter. how old will he be examined?