alchemy and even magic, where ancient thinkers tried to find the elixir of youth according to what laws does the human body age? and how these processes can be suspended, we will find out very soon. to reveal the secret of youth and health, the chinese emperor uzi in the second century bc turned to magicians, and the first to alchemists. in the third century, already our eras devoted their works to the search for a cure for immortality, let's trace all the historical stages, right now in search of the so-called source of eternal youth of the spring, which

composed legends went on a spanish expedition discovered florida in 1550, the venetian aristocrat luid, carnara, published a book. the art of longevity, which described the basic principles of life that help to stay healthy. the second attributed the dream to moderate nutrition and the absence of stress. the first scientific research in this area began at the end of the 19th century in 1882. the german professor august feisman published the first theory of aging, and in 1903 the russian scientist ilya melnikov introduced the term gerontology, the doctrine of old age. he's way experiments found out that nutrition affects life expectancy, after 25 years, also a russian scientist alexander bogdanov creates the world's first institute for blood transfusion. since he believes that

it is in this way that the body can be rejuvenated, however, during the next transfusion, scientists die at that time nothing was known about the compatibility of blood types a few years later, a swiss doctor. paul nihon develops a method for injecting stem cells. among his patients, i would have taken her out churchill and de gaulle during the second world war, almost all research in this area is suspended and resumed only after its completion today. there are many theories of aging, which can be conditionally divided into three main groups. immunological cellular or genetic new recipes for slowing down the aging process appear in barely a line every year, but after lengthy research and testing proves its effectiveness, far from everyone. literally

at the beginning of 2023, employees of the university of california at san diego developed a method potential slowing down of the cellular aging process with the help of a fluctuating genetic clock, which is the essence of the previous studies of this group of scientists showed that cells age as a result of two processes , a decrease in dna stability and a decrease in the energy produced by mitochondria energy centers, cell scientists came to the conclusion that aging will come later. if the cells switch between these two processes, the method was tested on yeast cells and obtained excellent results. what about the last

research by a group of scientists from the university of california san diego belarusian scientists think and we ourselves will ask our guests in the program studio what they are working on in this area. today, the head of the laboratory of neurophysiology of the institute of physiology of the academy of sciences of belarus svetlana georgievna hello hello so tell me like this in plain language. what is the method of such cell switching, how does it work? there is genetic information, which, let's say , of two varieties will be easier to compare. uh, our processes of forming memory and information on cellular level with a computer. but imagine that the genetic information that is stored in our dna in the genome. it is passed down to us from generation to mouth from our parents to our ancestors. this is the so-called hard drive. this is such a biological device. that's all that represents in the computer. well, where we are already uploading this, but what we are uploading

software is epigenetic information - this is our software software can be completely different depending on those factors the environment that a person encounters in life is both internal and external , how we adapt to them. and now all the most successful ones are stored on the hard drive, that is, in ours already a genius and uh , when scientists began to analyze, uh, what causes aging, the gnome wears out, but, because copying errors constantly occur, and uh, how a well-known fact that has been known since the fifties that every cell, and every day, occurs, well, a violation of the structure, here are double-strand breaks in dna from 10 to 50. these are the breaks that need to be repaired all the time in order to restore these double-strand breaks, for example. or in general

, a violation in dna requires information to be requested from the epigenome. and how often we request this information, so the cell gradually changes its essence. that is, it loses its identity. here it was a cell that, uh, performed a certain function. well, for example, it was a muscle cell. she worked beautifully. and suddenly she began to lose these functions and became turn into a connective. what is it associated with the loss of muscle tissue during aging and replace it with connective tissue, that is, on the one hand. these are dna repair processes on the other hand. in fact, this is the aging process. that is, this positive moment, which , well, let's say, the cell loses its identity and, accordingly , does not perform its function well let's not

put windows on it let's put linux on it, maybe it will work with it , but that will be a completely different story, though, a completely different interface, of course, and then the somatic cells simply began to reprogram the old somatic cells into others into young ones and they became live normally and began to work normally. thus, it is possible to take e cells from an old organism and move them to a young organism and it will live for quite a long time, but another moment, if we take cells from a young organism and move them to the old ones, but the term will die anyway, the question arose of how the interaction between these two watches gnome and epigino takes place and found that there is no direct path? yes? here is a straight line, and sometimes a short line, this is a lightning, yes, that is, a zigzag is always closer, that is, this is the opportunity to maneuver. this information provides, first of all

, new challenges for scientists. this means that it is necessary to reveal not only the secrets of our genome and epigenome separately, we interact with them. and this is already, well, a completely new interesting field for research of all scientists, in which, of course, those people who have a desire will be the winners. e , to scientific search and vigor, so to speak, thoughts, that is, all this could already be said that there is nothing directly sensational new, but there are prospects, and in this study there is every time. uh, each new step, and it is actually quite significant, and although for scientists, because. they work with it all the time these steps are natural and so we do very often. i think that belarusian geneticists are not always but evaluate. that their research is at the highest world level, because it seems to them that it was just a small step, but, well , they would write about them in the same vein, and you

can imagine how much it would turn out that there would be in belarus, well, even cooler than who is there harvard californian, yes, and so on, that is, all these studies. in fact, all this is in the world treasury of knowledge and all this is for the benefit of man. but then i propose, so to speak, to promote our scientists , my colleagues went to the institute of genetics to understand this topic in more detail. we can seize with solicitations. just something to regret, our fronts breathed, we set off on an expedition to purchase our ukraine, having traveled 171 km, we reached the dosha once out the window.

it dawned on me that she was born somewhere on a pawn to lure not from the sixth force, but for 200 people to live a new life. known in perth that minute on our tv channel is the fastest way to win the main prize. it is, of course, to give as many correct answers to the questions as possible. what does prospector do ? as far as i understand, the creative answer will be a wild cat. tower stability. once the participants of one

of the teams answered absolutely correctly all the questions, but the tower fell down anyway. our beauty and youth , according to scientists, is 25 percent dependent on genetics, and some even incurable diseases, the main manifestation of which is early aging, arise precisely

because of the breakdown of elements. dna is the well-known progeria, uh, which divides into childhood progeria and is called eugene mutations that code for lamin, that is, there is a violation of cell division and such children die before the age of 27 years. there is a progeria of adults. e, is caused by another gene, e, which is responsible for the normal work and everything is normal in the structure of our dna and causes changes in its active tissue leading to the development of various atherosclerosis. and such a disease manifests itself at the age of 30-40 , too, people already look, in general, quite elderly, and these diseases, unfortunately, are not treated, both in childhood and in adults and naturally symptomatic treatment. in general, purely genetically, youth is a healthy state of the organism. and it depends on this how early the external signs of aging will appear, for example, wrinkles in the study of youth

by geneticists around the world , several main directions can be distinguished. the first is the effect of oxidative stress on the body. if we say how it manifests itself, then it manifests itself, first of all, it will be increased fatigue, which, in general, is characteristic. probably all of us before appearance. ah, holy hair. e, in the early appearance - this means in the summer of 17-18 the first gray hairs already appear. this is the peculiarity of these gray hairs, what if we normalize our work of the antioxidant system, which copes with letter of credit stress. uh, then uh, these hairs disappear, that is, in the system, hair color is acquired here, of course. these are the enzymes of these oxidant systems. they are encoded, of course, by certain genes and mutations and changes in these genes and leads to a balance here and to an increased violation. the content in our body of these active e-e, oxygen biomolecules. at the institute of genetics, in belarus, such studies

were also carried out due to the extremely negative impact, by the way, dative stress on the body was proven, in addition to internal damage, our appearance also suffers. however , this problem is our scientists. they didn't leave without attention. a new direction that our institute is engaged in is cosmetology. uh, this is the condition of our skin, the condition of our hair, uh, and uh, there is a disease, that is, again, alopecia, that is, loss hair is quite a large group of diseases, and one of these diseases is androgenic-genetic alopecia, which is caused by e.g., it has a genetic nature, e. eh, these are the defects. to date, it has been established that every second woman is a carrier of these genes. uh, in men the disease manifests itself more often, we can talk about eight out of ten men, genetically ascertain the problem of hair loss has become more common in the younger population and can

manifest itself as early as the age of 20 years. rejuvenation this disease leads to the fact that they do not always immediately put the correct diagnosis, existing methods for the prevention and treatment of this disease. they allow you to stop slow hair loss. that is, if the diagnosis is made correctly, and here, of course, genetics comes to the rescue. that is, if people there in the family have a known case of alopecia, then you can apply for a genetic test, uh, and the doctors select the right increase, that is, the right prophylaxis, uh, and the person remains with his hair. and one more direction over which our genetics work. this photoaging is basically damage to the skin, uh, that's caused by either the sun's rays or ultraviolet rays. eh, and no matter how skeptical we are about this, it is believed that people subject to photoaging e and

their physiological age differ from the external one by 20 years, that is, a person looks 20 years older than he really is. the first sign of this photoaging, which is associated with genetic defects, is hyperpigmentation, that is, an increased content of some kind of moles there. freckles, too, this can be generally determined, uh, in the presence of certain defects of the gene and after the genetic diagnosis is established, a set of cosmetics is prescribed that will protect the skin. you are watching the science project nearby and don't miss any further. why do our cells stop actively dividing as we age? let's take a look at how our brains age. and together we will study the new rule of medical examination. management through

contingencies enter the entire public state of a certain shock now is the main strategy that will use the west and beyond laws by way. through elections. radicals to power. they will never come, the people hate them by military means. now belarus cannot be defeated. so, the stake will be placed on terror. extremism is not before anything the west will not stop any means will be thrown for belarus in their scenario of one twenty-fourth twenty-fifth year , an attempt at any cost to blow up the situation from within. today we must be ready every day to defend our world, including the sovereignty project objectively. do not miss new releases on tv channel belarus 24. a show where participants demonstrate speed

ingenuity and test their intellect, which today minsk will oppose entrusted due to which we will win due to speed due to intelligence due to knowledge of sports we will try to win. the most important thing is not to worry, he believes himself in his knowledge of questions that will make even experienced athletes worry. who won the english football league cup 22-23. andrew manchester city sorry mariline manchester united manchester united correct answer the nationality of which state did the footballer renant brisan change to play for the national team of belarus was the first brazil brazil unconditionally? this is the correct answer to everyone good luck. let the strongest win

, watch the intellectual project heading on our tv channel. we return to the studio. i remind us at a party. today the head of the laboratory of neurophysiology of the institute of physiology of the academy of sciences of belarus svetlana pashkevich, svetlana dahlia. let's take a look at how our body ages. well, let's make it clear that genetics is genetics, but still some processes, they are natural in the body, because we change the cellular composition, our blood is constantly updated. uh, we are renewing the cells of our body. for all of our lives. we can change up to 11 bodies, that is , imagine yourself when you were born. here is your body and imagine yourself. now isn't it

the same body fundamentally , colossal changes have taken place and the only cells that have remained with us. all this time. these are the cells of the nervous system and the heart, and that's all. the rest of it, uh, was re-created by our body and was created and that eating food from those environmental influences that we were exposed to, and therefore the main attention, of course, in the aging process is paid to the aging of the brain and the aging of the heart, one of the theories that the heart has a finite number of strokes. for all time, and the slower it beats, the longer a person lives, and people who live a more measured life, who communicate with each other, who do not have a cognitive deficit, that is. they are perfectly aware of themselves in the environment, their place in this environment, who have procreation, when they see themselves in

their children, first of all, and they see their future not in themselves in their personal immortality, but the future in their children, the future in that the environment in which they will live then it prolongs the life of these people and reliably. we can say that centenarians have just such an outlook on life. what about accumulation? and so on. yes, this happens inevitably and every time we can say that the genetic information can get worse, but in fact, it's not only the genome that really deteriorates, but it's also the epigenome, and the epigynome determines not only, but those signs that accidentally fall on us. well, and those that we ourselves program ourselves. that is why people who are engaged in healing practices, who not only lead a healthy lifestyle, but understand what is really useful for the body. and what could be? well

, you know, with such a bright wrapper, uh, in order to sell you something, which, well, just to people want to earn. yes, on your desire to be healthy, therefore , people's awareness of the real processes that happen to us and the acceptance of old age, after all, why do we think that we should be immortal? well, we can be immortal in our children, and most likely, those people who have no descendants die, but those who have children, who have grandchildren, great-grandchildren, but this is already forever true, that is, you already see how far you are generations ahead. this is your information. yeah it's live but accent focus on aging. it is necessary only from the point of view to bring maximum benefit and not only to your health to the body. well, society and theory. e aging that exists, they first of all consider, for example, how do we preserve

the cognitive functions of the brain and, e , what we are studying in the laboratory is the possibility of recovery, and in case of some emergency violations or damage with the help of endogenous resources. uh, it's probably already known stem cells. so called the process of neurogenesis, which takes place in certain limited areas of the brain, but allows to a greater extent, of course, but to restore our functions of orientation in the space of storing information, and, uh, storing information. and therefore, if we move, if we learn a new area, if we learn a new language, get to know new people, then this allows us to preserve the functions of neurogenesis. here in these areas. and the same is the area that is responsible for our organs of the internal sphere. and so if we

doing exercises in the fine motor cortex is directly related to the preservation of cognitive functions, but because this fine motor skills of the hand is our cerebral cortex, which when we touch and massage with the handles like this and do not forget that the brain, uh, works only when when all his cells are fed, he does not feed the loafers, and therefore, if some structures of the brain. for some reason they don't work for a long time. well , for example, you just lie on the sofa, look at the tv, well, you didn’t get up and didn’t pass, but be sure to walk around, at least there must be some kind of change, physical activity and intellectual, and this will massage well enough. uh, your brain will not let those neurons die that once learned to write beautifully at school. many dahlias. thank you very much, everything, as usual, is simply accessible and, most importantly, interesting and useful. and we continue. today it is reliably known only, and then the only elixir of youth.

actually. this is a healthy lifestyle and no matter how skeptical someone is about it. there are facts according to statistics, those people age more slowly who go in for sports, get enough sleep , eat right and regularly undergo medical examinations from this year. by the way, in our country there are new approaches to clinical examination. what has changed and, most importantly, why did my colleagues find out? in the rubric checked on myself. so that they don’t get confused and the index signs come to the office in which medical examinations are carried out in clinics , they are even applied on the floor. welcome to dispensary. and this procedure begins with a questionnaire, the medical examination begins with the fact that the questionnaire is filled in the questionnaire. eat

questions on answers to which conclusions can be drawn, if a person has a sharp development of the most common diseases that are socially significant, these are diseases of the respiratory system, the circulatory system, oncology and e, are predisposed to sugar diameter, the patient fills out this document, the nursing staff working in these offices evaluates and, depending on this evaluation is already further determined. what examinations yes and do the patient need them? after the patient has filled out the questionnaire, a set of mandatory procedures is carried out with him. this dimension blood pressure eye pressure check the condition of the oral cavity, and then the medical staff finds out. what is your body mass index, it is calculated by weight and height. another important thing is the waist size, since these indicators are directly related to the state of the endocrine system. yes, and the correct one is more precisely the healthy work of the whole organism. if any of the indicators is not normal, these are the risks of a variety of diseases. depending on these risks, it

will pass before the examination and will be sent for tests, if necessary, for a cardiogram to a general practitioner. if necessary, then to a russian specialist, and tests are given even on the same day and a cardiogram can be done, and then the patient can make an appointment at a convenient time for him to see a doctor. there they will explain the results to him and then, depending on the results, they will be sent for yes examination, or they will tell him how to behave . what lifestyle and when to come next time? the medical examination procedure itself takes no more than 15 minutes and you have specific recommendations and directions in your hands. based on the results of the survey, you need to pass will take a cardiogram to pass cholesterol and visit a general practitioner to undergo medical examination from the age of 18. all citizens of our country will need it. according to the latest decree, which was issued on august 9

, the twenty-second year, number 83, the conditionally adult population is divided into two groups. the first group is from 18 to 39 years old, the second is from 40 and older, the first group is patients. they undergo medical examination once every three years, the second time a year, but if a person has a disease, then it does not matter. how old will he be examined for this disease, according to clinical protocols, in general , such a practice is a general global trend, because it is much easier to prevent a disease than to treat it. it has long been calculated for state budgets, among other things, it is more profitable to engage in prevention, so that people themselves come. ah, deliberately. with their health, they followed the rules of a healthy lifestyle and got sick less, but because the person himself spends much more money on the treatment of the patient. as a result, you have to buy medicines to go to the doctors. it wastes both time and money to

the convenience of patients in some polyclinics , depending on the number of people visiting it, several rooms are open for medical examinations; you can get to it by appointment or simply on a first come first served basis. the ancient greek sage biant preinsky spoke from youth to old age in the 4th century bc. take away the supply of wisdom, for no, the property is more reliable and indeed become. the older ones are wiser and understand that age is just a number in the passport. the most important thing is the state of mind. and, of course, health. well, in these matters, as we have seen today, science is right next to it.

what secrets are hidden by the greatest shrines of christianity ? well, i don’t think that in spiritual terms this can be a coincidence, does the name affect the character and fate of a person, these softly holy i would call her, but to live like this i to that is you having competition. why does the bible call to be joyful sometimes earthly joy, bodily joy, it’s like that, sometimes it passes very quickly, and the joy that a person receives from communicating with god in the church, then this joy somehow turns out that fills him every day life. why do they ring bells in temples? it is known that the bells?