and the rich architectural heritage of belarus today, our amazing journey will pass through a wonderful city with many different unique places of interest with its amazing atmosphere of architectural monuments. there are only two svislochs, a synagogue and a gymnasium. but there are a whole alley of monuments to heroes, you won’t believe it, but i am now in a real bunker, which has been preserved here since the cold war and on the second floor on the night of november 22-23, 1812. travel with us to belarus 24. generations just to respect.

today is the year of albus, where what else will lose the watchful wheel was a new one. we ourselves do not respect it, we pass the vedas into the experience of calmness. this is our death's hand. just happy moments develop accompanying traditions.

people thought about this question in the most ancient times; it was raised in egyptian indian and chinese treatises, which were found and deciphered today. it ’s just that experiments in this area sometimes ended tragically precisely with such circumstances, for example, the chinese emperor died. you appreciate juanda in the modern world , fortunately, things do not reach such extremes.

although the search for him continues, to this day, in the next half hour, we will join them in order to understand how close science is today, how the discovery of the elixir of youth is about him, because it is possible that she is already very close in the studio of ekaterina beletskaya hello and do not miss in a programme. alchemy and even magic, where ancient thinkers tried to find the elixir of youth does the human body age according to laws? and how these processes can be suspended, we will find out very soon. to reveal the secret of youth and health, the chinese emperor uzi in the second century bc turned to magicians, and the first to alchemists. in the third century, already our eras

devoted their works to the search for a cure for immortality, let's trace all the historical stages right now. in search of the so-called source of eternal youth, the spring, which was used to make legends , the spanish conquistador juan poncede leon went on an expedition he, of course, did not find the spring. but florida was discovered in 1550 by the venetian aristocrat luigi carnara, who published the book the art of longevity, in which he described the basic principles of life that help them stay healthy. the author attributed the sleep to moderate nutrition and the absence of stress. the first scientific study. in this area began at the end of the xix century. in 1882. the german professor august feisman publishes the first theory of aging, and in 1903 the russian scientist ilya

mechnikov introduces the term gerontology, the doctrine of old age, he found out through experiments. nutrition affects life expectancy, after 25 years, also a russian scientist alexander bogdanov creates the world's first institute for blood transfusion. since he believes that it is in this way that the body can be rejuvenated, however, during the next transfusion, scientists die at that time nothing was known about the compatibility of blood types a few years later, a swiss doctor. paul nihon develops a method for injecting stem cells. among his patients, i would like her winston churchill and charles de gaulle during the second world war, almost all research. in this area , they are suspended and resumed only after it ends. today, there are many theories of aging, which can be divided into three main groups. immunological cellular and genetic.

new recipes for slowing down the aging process appear barely on the line every year, but after lengthy research and testing , not all prove their effectiveness. literally at the beginning of 2023, employees at the university of california at san diego developed a way to potentially slow down the process of cellular aging through a fluctuating genetic clock, which is the essence of the previous study of this group of scientists showed cells age as a result of two processes , a decrease in the stability of dna and a decrease in the energy produced by the mitochondria energy centers, the cells scientists came to the conclusion that aging will come later.

if the cells switch between these two processes, the method was tested on yeast cells and obtained excellent results. what about the latest research by a group of scientists from the california university of san diego thinks belarusian scientists and what they are working on in this area , we ourselves will ask our guests in the studio of the program. today, the head of the laboratory of neurophysiology of the institute of physiology of the academy of sciences of belarus svetlana georgievna hello hello so tell me like this in plain language. what is the method of such cell switching, how does it work? there is genetic information, which, let's say , of two varieties will be easier to compare. uh, our processes of forming memory and information at the cellular level with a computer. and here imagine that the genetic information

that is stored in our dna in the genome. it is passed down to us from generation to mouth from our parents to our ancestors. this is the so-called hard drive. this is such a biological device. that's all that represents in the computer. well, where we will load. but the fact that we download the software is epigenetic information - this is our software , the software can be completely different depending on the environmental factors with which it meets a person in life is both internal and external , how we adapt to them. and now all the most successful ones are stored on the hard drive, that is, in our already genius and uh , when scientists began to analyze, uh, what causes aging, aging, the genome wears out, but, because copying errors constantly occur, and uh, how a well-known fact that has been known

since the fifties that every cell, and every day, happens, well, a violation of the structure, here are double-strand breaks in dna from 10 to 50. these are the breaks that it is necessary to restore all the time in order to restore these two. for breaks, for example, or even a violation in dna , information must be requested from the epigenome. and how often we request this information, so the cell gradually changes its essence. that is, it loses its identity. here it was a cell that, uh, performed a certain function. well, for example, it was a muscle cell. she worked beautifully. and suddenly it began to lose these functions and began to turn into a connective one. what does it associate with loss of muscle tissue during aging and replace it with connective tissue, that is, on the one hand. these are dna repair processes on the other hand. in fact, this is the

aging process. that is, this positive moment , which, well, let's say, the cell loses its identity and, accordingly , does not perform its function well, let's not put windows on it. let's put linux, maybe, he will work with it, but it will be a completely different story, however, a completely different interface, of course. and then the somatic cells simply began to reprogram the old somatic cells into others into young ones and they began to live normally and began to work normally. thus, you can take e cells from an old organism, move them to a young organism and it will live for quite a long time, but another moment, if we take cells from a young organism and move them to the old ones, but the meaning will still die the question arose of how the interaction between these two watches

gnome and the epigen takes place and found that there is no direct path? yes? here is a straight line, and sometimes a short line, this is a lightning, yes, that is, a zigzag is always closer, that is, this is the opportunity to maneuver. this information provides, first of all , new challenges for scientists. this means that it is necessary to reveal not only the secrets of our genome and epigenome separately, we interact with them. and this is already, well, a completely new interesting field for the study of all scientists, in which, of course , those people who have a desire will be the winners. e, to scientific research and cheerfulness , so to speak, thoughts are all. it could already be said that there was something directly sensational new, but not perspective. e. in this study. there is every time. uh, each new step, and it is actually quite significant, and although for scientists,

because. they work with it all the time these steps are natural and so we do very often. i think that belarusian geneticists do not always, but appreciate it. what is their their research is at the highest world level, because it seems to them that it was just a small step, but, well, they would write about them in the same vein, and you can imagine how much it would turn out that belarus is even cooler there than harvard california university, and so on, that is, these are all studies. in fact, all this is in the world treasury of knowledge and all this is for the benefit of man. but then i propose, so to speak , to promote our scientists, my colleagues went to the institute of genetics to figure out more in detail in this thread. significance of belarus

the geopolitical significance of belarus significantly exceeds the scale of our country and its resource capabilities that we have been for 30 years. we live in a peaceful, peaceful independent belarus due to the fact that every day we prepare for war, war does not forgive. weakness a-a war does not forgive unwillingness we are peaceful people these are the first lines of our national anthem no one believes in the possibility of war. and why are the poles progressively increasing their military spending, we understand that if we now if we don't finish it here, we'll have to finish it. our children nuclear weapons means of ensuring our security means of deterring those madmen who would like to repeat the forty-first year of the markov project nothing personal only the truth, which is always more interesting than posts, watch on

belarus 24 tv channel. they are passionate about what they love and try to popularize it among the younger generation. here there is usually an egg of a kulik bird called a lapwing. this is a typical egg paint, it was able to detect. to the lapwing's nest, which had a unique the white masonry of their broad outlook and inquisitive mind can only be envied. i am walking along a defective road, the second road from the town of olshany, yakaya, was a laying of the 30s and the duck left will be 100 years old. i've been here from the platform horses rode different waters. well, already all god’s cars are driven by people

who live in the woods and do everything for the development of their small motherland. well, i think i’m not talking about that a little bit, i want the same kind of my san for mercy in this. e, such such e-handiness, i didn’t decrease, so that without a word in the capital, see the project politics on tv channel belarus 24. according to scientists, our beauty and youth are 25 percent dependent on genetics, and some even incurable diseases, the main manifestation of which is early aging, arise precisely because of the breakdown of elements. dna is a well-known progeria

, uh, which is divided into childhood progeria and is caused by eugene mutations that encode lamin, that is, there is a violation of cell division and such children die before the age of 27 and there is adult progeria. uh, caused by another gene, uh, which is responsible for the normal operation and everything is normal in the structure of our dna and causes changes in its active tissue leads to the development of various atherosclerosis and this disease appears at the age of 30-40, too, people look already , in general, quite old, and these diseases, to unfortunately, they are not treated, both in childhood and in adults, and naturally symptomatic treatment. in general, purely genetically, youth is a healthy state of the body. and it depends on this how early the external signs of aging, for example, wrinkles, will appear. in the study of youth by geneticists around the world , several main directions can be distinguished.

the first is the effect of oxidative stress on the body. if we say how it manifests itself, then it manifests itself, first of all, it will be increased fatigue, which, in general, is characteristic. probably for all of us this is an early appearance. ah, holy hair. e, in the early appearance - this means in the summer of 17-18 the first gray hairs already appear. this is the peculiarity of these gray hairs, what if we normalize our work with antioxidant system that copes with letter of credit stress. uh, then uh, these hairs disappear, that is, in the system, hair color is acquired here, of course. these are the enzymes of these oxidant systems. they are encoded. naturally, certain genes and mutations and changes in these genes lead to a balance here and to a violation of the content in our body of these active uh, oxygen biomolecules. at the institute of genetics, we in belarus, such studies were also carried out due to the extremely negative impact, by the way, stress on the body was proven, except

internal damage suffers and our appearance. however, this problem is our scientists. they didn't leave without attention. a new direction that our institute is engaged in is cosmetology. uh, this is the condition of our skin, the condition of our hair, uh, and uh, there is a disease , that is, again, alopecia, that is, hair loss is quite an extensive group of diseases and one of, uh, these diseases is androgenetic alopecia, which is caused by e, precisely has a genetic nature, e by carriage. eh, these are defects. to date, it has been established that every second woman is a carrier of these genes. yes, the disease is more common in men. there you can talk about eight out of ten men, genetically ascertaining the problem of hair loss has become more common in a younger population and can manifest itself as early as the age of 20 years.

the rejuvenation of this disease leads to the fact that they always immediately make the correct diagnosis, the existing methods of prevention and treatment of this disease allow me to stop and slow down hair loss. that yes, if the diagnosis is correctly made, and here, of course, genetics comes to the rescue. that is, if people there in the family have a known case of alopecia, then you can apply for a genetic test, uh, and the doctors select the right increase, that is, the right prophylaxis, uh, and the person remains with his hair. and another area that our geneticists are working on is photoaging. this is generally damage to the skin, which is caused either by sunlight or ultraviolet rays. eh, and no matter how we feel about it skeptical, but it is believed that e in people prone to photoaging e and their physiological age. e, from the external e

differs by 20 years, that is, a person looks 20 years older than he really is. the first sign of this photoaging, which is associated with genetic defects, is hyperpigmentation, that is, an increased content of some kind of freckle moles, this can also be generally determined, if there are certain defects in the gene and after the genetic diagnosis is established, it is assigned care set cosmetics that will protect the skin. you are watching the science series project we will not miss further. why do our cells stop actively dividing as we age? let's take a look at how our brains age. and together we will study the new rule of medical examination. in a vacuum

, there is a need for answers to questions hovering in the air, at least in the world and the main challenges of national interest. belarus in front of the building of the secretary is already reserved. there are many economic processes here that are mutually beneficial. on tv channel belarus 24

management through unforeseen circumstances enter the entire public state of a certain shock now is the main strategy that will use the west and beyond the laws through. through elections. radicals to power. they will never come, the people hate them by military means. now belarus cannot be defeated. so, the stake will be placed on terror. extremism is not before anything the west will not stop, any means will be thrown for belarus in their scenario. one , two, four twenty-fifth years, an attempt at any cost to blow up the situation from within. today, we must be prepared every day for protection of their world, and including the sovereignty project objectively. don't miss the new releases on belarus 24 tv channel

. back to the studio. i remind us at a party. today the head of the laboratory of neurophysiology of the institute of physiology of the academy of sciences of belarus svetlana pashkevich, svetlana dahlia. let's take a look at how our body ages. well, let's just say it's clear that genetics is genetics, but still some processes, they are natural in the body, because we are constantly changing the cellular composition of our blood is renewed. uh, we are renewing the cells of our body. for all of our lives. we can change up to 11 bodies, that is , imagine yourself when you were born. here is your body and imagine yourself. now isn't it the same body fundamentally , colossal changes have taken place and the only cells that have remained with us. all this time. these are the cells of the nervous system and the heart, and everything

else, uh, was re-created by our body and was created and that and food. uh, food from those environmental exposures which were subjected to, and therefore the main attention, of course, in the aging process is given to the aging of the brain and the aging of the heart , one of the theories is that the heart has a finite number of beats. for all time , and the slower it beats, the longer a person lives, and people who live a more measured life, who communicate with each other, who do not have a cognitive deficit, that is. they are well aware of themselves in the environment, their place in this environment, who have procreation, when they see themselves in their children, first of all, they they see their future not in themselves in their personal immortality, but the future in their children , the future in the environment in which they will live

, then this prolongs the life of these people and reliably. we can say that centenarians have just such an outlook on life. what about accumulation? and so on. yes, this happens inevitably, and every time we can say that genetic information can get worse, but in fact, it's not only the genome that really deteriorates, but it's also the epigenome, and epin causes not only and those signs that accidentally fall on us. well, and those that we ourselves program ourselves. that is why people who are engaged in healing practices, who not only lead a healthy lifestyle, but understand what is really useful for the body. and what could be? well , you know, with such a bright wrapper, uh, in order to sell you something, which, well, people just want to earn. yes, on your desire

to be healthy, therefore, awareness of people's awareness of those real processes that are happening to us and the acceptance of old age after all, why do we think that we should be immortal? well, we can be immortal in our children, and most likely, those people who have no descendants die, but those who have children, who have grandchildren, great-grandchildren, but this is already forever true, that is, you already see how far you are generations ahead. this is your information. yes, they are alive, but focus on their own aging. it is necessary only from the point of view to bring maximum benefit and not only to your health to the body. well, society and theory. e aging that exist, they first of all consider, for example, how can we preserve the cognitive functions of the brain and, uh , what we are researching in the laboratory is the possibility of recovery, and in case

of some emergency violations or damage with the help of endogenous resources. uh, it's probably already known stem cells. the so-called process of neurogenesis, which takes place in certain limited areas of the brain, but allows to a greater extent, of course, but to restore our function of orientation in space remembering information, and, uh, storing information. and therefore, if we move, if we get to know a new area, if we learn new languages, get to know new people, then this allows us to preserve the functions of neurogenesis. here in these areas. and the same is the area that is responsible for our organs of the internal sphere. and therefore, if we do exercises in the fine motor skills of the hands, it is directly related to the preservation of cognitive functions, but because this fine motor skills of the hand is our cerebral cortex, which when we sort through the handles like this. we

massage and don't forget that the brain, uh , works only when all its cells are fed, it does not feed idlers, and therefore, if some structures of the brain. for some reason they don't work for a long time. well, for example, uh, you just lie on the couch, look at the tv, well, you didn’t get up and didn’t pass, but be sure to walk around, at least there should be some change in motor activity and intellectual activity and this will massage your brain quite well and will not let those die neurons that once learned to write beautifully at school. many. thank you very much, everything, as usual, is simply accessible and, most importantly, interesting and useful. and we continue. today it is reliably known only, and then the only one or in the power of youth. in fact, this is a healthy lifestyle and no matter how skeptical someone is about it. there are facts according to statistics that people who go in for sports, get enough sleep, eat right and

regularly undergo medical examinations from this year age more slowly. by the way, in our country there are new approaches to clinical examination. what changed and most importantly, why did my colleagues find out? in the rubric checked on myself. so that they don’t get confused and the index signs come to the office in which medical examinations are carried out in clinics, they are even applied on the floor. welcome to dispensary. this procedure begins with a questionnaire, the medical examination begins with the fact that a questionnaire is filled in the questionnaire. there are questions on the answers to which conclusions can be drawn, if a person is at risk of developing the most common socially significant diseases, this is a disease of the respiratory system

circulatory oncology and e, predisposed to diabetes mellitus, and the patient fills out this document, the nursing staff working in these offices evaluates and, depending on this assessment, is already further determined. what examinations yes and do the patient need them? after the patient has filled out the questionnaire, a set of mandatory procedures is carried out with him. this measurement of blood pressure is an eye pressure check of the condition of the oral cavity, and then the medical staff finds out. what is your body mass index, it is calculated by weight and height. another important thing is the waist size, since these indicators are directly related to the state of the endocrine system. yes, and the correct one is more precisely the healthy work of the whole organism. if any of the indicators is not normal. these are already the risks of a variety of diseases, depending on these tourists, he will pass before the examination , tests will be sent, if necessary, a cardiogram to a general practitioner doctor, if